CA2391071A1 - Multiwell apparatus - Google Patents

Multiwell apparatus Download PDF

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Publication number
CA2391071A1
CA2391071A1 CA002391071A CA2391071A CA2391071A1 CA 2391071 A1 CA2391071 A1 CA 2391071A1 CA 002391071 A CA002391071 A CA 002391071A CA 2391071 A CA2391071 A CA 2391071A CA 2391071 A1 CA2391071 A1 CA 2391071A1
Authority
CA
Canada
Prior art keywords
lid
channel
negative pressure
multiwell plate
plate body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002391071A
Other languages
French (fr)
Other versions
CA2391071C (en
Inventor
John P. Hall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of CA2391071A1 publication Critical patent/CA2391071A1/en
Application granted granted Critical
Publication of CA2391071C publication Critical patent/CA2391071C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method for assembling a multiwell plate assembly, and a multiwell plate assembly prepared thereby, are provided. The method includes providing a lid for a multiwell plate body having at least one channel being formed therethrough;
positioning the lid in proximity to a gasket member; applying sufficient negative pressure to the channel to draw the gasket member towards the lid; positioning the lid above a multiwell plate body, while continuing to apply negative pressure to the channel;
emplacing the lid on the multiwell plate body; and, releasing the negative pressure from the channel.
Advantageously, as will be recognized by those skilled in the art, various gasket members can be used in conjunction with the subject method, without altering the method. In this manner, gaskets can be selected based on their suitability for use with various biological and/or chemical samples which may be used in the bioassays.

Claims (14)

1. A multiwell plate assembly comprising:
a multiwell plate body having a plurality of wells formed therein; and, a lid formed for emplacement on said multiwell plate body, said lid and said plate body encompassing a volume with said lid being emplaced on said plate body, wherein at least one channel is formed through said lid, said at least one channel communicating with said encompassed volume with said lid being emplaced on said body.
2. An assembly as in claim 1 further comprising latchable members formed on said lid for latching onto said multiwell plate body.
3. An assembly as in claim 1 further comprising a gasket member disposed in said encompassed volume.
4. An assembly as in claim 3 wherein said gasket member is in at least a partially compressed state being disposed in said encompassed volume.
5. An assembly as in claim 1 wherein said lid includes a top portion, said at least one channel being defined in said top portion, wherein said top portion being shaped convexly downwardly in a natural state.
6. A method of assembling a multiwell plate assembly, said method comprising:
providing a lid having at least one channel being formed therethrough;
positioning said lid in proximity to a gasket member;

applying sufficient negative pressure to said at least one channel to draw said gasket member towards said lid;
positioning said lid above a multiwell plate body having a plurality of wells defined therein, while continuing to apply negative pressure to said at least one channel;
emplacing said lid on said multiwell plate body; and, releasing the negative pressure from said at least one channel.
7. A method as in claim 6 further comprising positioning a vacuum pick apparatus above said lid, said negative pressure being applied to said at least one channel via said vacuum pick apparatus.
8. A method as in claim 7, wherein said vacuum pick apparatus is partitioned into at least first and second zones, negative pressure being generated in said first and second zones being separately controlled, said negative pressure being applied to said at least one channel via said first zone.
9. A method as in claim 8, wherein said lid is formed solid below said second zone.
10. A method as in claim 6, wherein said emplacing includes latching latchable members formed on said lid onto said multiwell plate body.
11. A method as in claim 6, wherein said lid includes a top portion, said at least one channel being defined in said top portion, wherein said top portion being shaped convexly downwardly in a natural state.
12. A method as in claim 6 further comprising applying a negative pressure to said lid.
13. A method as in claim 12, wherein said negative pressure applied to said lid is separately controlled from said negative pressure applied to said at least one channel.
14
CA2391071A 2001-11-19 2002-06-21 Multiwell apparatus Expired - Fee Related CA2391071C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33273501P 2001-11-19 2001-11-19
US60/332,735 2001-11-19
US10/108,640 2002-03-29
US10/108,640 US7125522B2 (en) 2001-11-19 2002-03-29 Multiwell apparatus

Publications (2)

Publication Number Publication Date
CA2391071A1 true CA2391071A1 (en) 2003-05-19
CA2391071C CA2391071C (en) 2010-06-01

Family

ID=26806111

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2391071A Expired - Fee Related CA2391071C (en) 2001-11-19 2002-06-21 Multiwell apparatus

Country Status (5)

Country Link
US (2) US7125522B2 (en)
EP (1) EP1312414A3 (en)
JP (1) JP4233845B2 (en)
AU (2) AU2002301676B2 (en)
CA (1) CA2391071C (en)

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US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
DE10339158A1 (en) * 2003-08-26 2005-04-07 Evotec Technologies Gmbh Handling device for closing elements for sample carriers such as titer plates and micro-titer plates comprises holding body for holding closing element on bearing surface, recess in bearing surface, and suction unit
US20060013984A1 (en) * 2003-09-19 2006-01-19 Donald Sandell Film preparation for seal applicator
US20060011305A1 (en) * 2003-09-19 2006-01-19 Donald Sandell Automated seal applicator
US20050226779A1 (en) 2003-09-19 2005-10-13 Oldham Mark F Vacuum assist for a microplate
US20060029948A1 (en) * 2003-09-19 2006-02-09 Gary Lim Sealing cover and dye compatibility selection
US20050225751A1 (en) * 2003-09-19 2005-10-13 Donald Sandell Two-piece high density plate
US7460223B2 (en) * 2003-09-19 2008-12-02 Applied Biosystems Inc. Inverted orientation for a microplate
US20050232818A1 (en) * 2003-09-19 2005-10-20 Donald Sandell Single sheet seal applicator and cartridge
US20050226780A1 (en) * 2003-09-19 2005-10-13 Donald Sandell Manual seal applicator
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US20050221358A1 (en) * 2003-09-19 2005-10-06 Carrillo Albert L Pressure chamber clamp mechanism
US20050287573A1 (en) * 2004-06-18 2005-12-29 North Dakota State University Lined multi-well plates
US20080006202A1 (en) * 2006-06-26 2008-01-10 Applera Corporation Compressible transparent sealing for open microplates
US20080000892A1 (en) * 2006-06-26 2008-01-03 Applera Corporation Heated cover methods and technology
DE202007002538U1 (en) * 2007-02-21 2007-06-06 Krebs, Torsten Device for gasifying biological tissue and bacterial cultures, comprises a single-piece sample reception block exhibiting fluid supply arrangement, and gasifying head for supplying gasifying medium connected with the reception block
JP5680950B2 (en) * 2009-12-10 2015-03-04 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Multiwell plate and lid
CN103028456B (en) * 2012-08-10 2014-10-08 卢瑾 Detected specimen preserving and processing method and corresponding device
GB2528671B (en) * 2014-07-25 2018-11-14 Rhys Jones Gethin Container handling device
EP3261761B1 (en) 2015-02-27 2022-04-13 Corning Incorporated Fitted lid for multi-well plate
US10227556B2 (en) * 2015-09-04 2019-03-12 Wayne State University Cell culture devices for biomimetic and pathomimetic cell cultures
WO2018144161A1 (en) * 2017-01-31 2018-08-09 Counsyl, Inc. High throughput automatic diagnostic system for removing microplate lids
WO2023141047A1 (en) * 2022-01-20 2023-07-27 Invitae Corporation Device and method for placement and securement of film

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Also Published As

Publication number Publication date
EP1312414A2 (en) 2003-05-21
AU2009200345C1 (en) 2011-09-01
US20060280654A1 (en) 2006-12-14
AU2009200345B2 (en) 2011-03-10
US7572411B2 (en) 2009-08-11
US20030096427A1 (en) 2003-05-22
AU2002301676B2 (en) 2008-12-11
AU2009200345A1 (en) 2009-02-19
CA2391071C (en) 2010-06-01
EP1312414A3 (en) 2004-03-17
JP4233845B2 (en) 2009-03-04
JP2003227839A (en) 2003-08-15
US7125522B2 (en) 2006-10-24

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EEER Examination request
MKLA Lapsed

Effective date: 20180621