CA2391071C - Multiwell apparatus - Google Patents
Multiwell apparatus Download PDFInfo
- Publication number
- CA2391071C CA2391071C CA2391071A CA2391071A CA2391071C CA 2391071 C CA2391071 C CA 2391071C CA 2391071 A CA2391071 A CA 2391071A CA 2391071 A CA2391071 A CA 2391071A CA 2391071 C CA2391071 C CA 2391071C
- Authority
- CA
- Canada
- Prior art keywords
- lid
- channel
- negative pressure
- multiwell plate
- plate body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Abstract
A method for assembling a multiwell plate assembly, and a multiwell plate assembly prepared thereby, are provided. The method includes providing a lid for a multiwell plate body having at least one channel being formed therethrough; positioning the lid in proximity to a gasket member; applying sufficient negative pressure to the channel to draw the gasket member towards the lid; positioning the lid above a multiwell plate body, while continuing to apply negative pressure to the channel; emplacing the lid on the multiwell plate body; and, releasing the negative pressure from the channel. Advantageously, as will be recognized by those skilled in the art, various gasket members can be used in conjunction with the subject method, without altering the method. In this manner, gaskets can be selected based on their suitability for use with various biological and/or chemical samples which may be used in the bioassays.
Claims (14)
1. A multiwell plate assembly comprising:
a multiwell plate body having a plurality of wells formed therein; and, a lid formed for emplacement on said multiwell plate body, said lid and said plate body encompassing a volume with said lid being emplaced on said plate body, wherein at least first and second channels are formed through said lid, said channels communicating with said encompassed volume and with an environment external to said lid with said lid being emplaced on said body, wherein a first opening is formed in said lid to communicate with the external environment, said first channel communicating with said first opening and extending through said lid to a second opening communicating with said encompassed volume, said second channel communicating with said first opening and extending through said lid to a third opening communicating with said encompassed volume, said second and third openings being spaced apart.
a multiwell plate body having a plurality of wells formed therein; and, a lid formed for emplacement on said multiwell plate body, said lid and said plate body encompassing a volume with said lid being emplaced on said plate body, wherein at least first and second channels are formed through said lid, said channels communicating with said encompassed volume and with an environment external to said lid with said lid being emplaced on said body, wherein a first opening is formed in said lid to communicate with the external environment, said first channel communicating with said first opening and extending through said lid to a second opening communicating with said encompassed volume, said second channel communicating with said first opening and extending through said lid to a third opening communicating with said encompassed volume, said second and third openings being spaced apart.
2. An assembly as in claim 1 further comprising latchable members formed on said lid for latching onto said multiwell plate body.
3. An assembly as in claim 1 further comprising a gasket member disposed in said encompassed volume.
4. An assembly as in claim 3 wherein said gasket member is in at least a partially compressed state being disposed in said encompassed volume.
5. An assembly as in claim 1 wherein said lid includes a top portion, said at least one channel being defined in said top portion, wherein said top portion being shaped convexly downwardly in a natural state.
6. A method of assembling a multiwell plate assembly, said method comprising:
providing a lid having at least one channel being formed therethrough;
positioning said lid in proximity to a gasket member;
applying sufficient negative pressure to said at least one channel to draw said gasket member towards said lid;
positioning said lid above a multiwell plate body having a plurality of wells defined therein, while continuing to apply negative pressure to said at least one channel;
emplacing said lid on said multiwell plate body; and, releasing the negative pressure from said at least one channel.
providing a lid having at least one channel being formed therethrough;
positioning said lid in proximity to a gasket member;
applying sufficient negative pressure to said at least one channel to draw said gasket member towards said lid;
positioning said lid above a multiwell plate body having a plurality of wells defined therein, while continuing to apply negative pressure to said at least one channel;
emplacing said lid on said multiwell plate body; and, releasing the negative pressure from said at least one channel.
7. A method as in claim 6 further comprising positioning a vacuum pick apparatus above said lid, said negative pressure being applied to said at least one channel via said vacuum pick apparatus.
8. A method as in claim 7, wherein said vacuum pick apparatus is partitioned into at least first and second zones, negative pressure being generated in said first and second zones being separately controlled, said negative pressure being applied to said at least one channel via said first zone.
9. A method as in claim 8, wherein said lid is formed solid below said second zone.
10. A method as is claim 6, wherein said emplacing includes latching latchable members formed on said lid onto said multiwell plate body.
11. A method as in claim 6, wherein said lid includes a top portion, said at least one channel being defined in said top portion, wherein said top portion being shaped convexly downwardly in a natural state.
12. A method as in claim 6 further comprising applying a negative pressure to said lid.
13. A method as in claim 12, wherein said negative pressure applied to said lid is separately controlled from said negative pressure applied to said at least one channel.
14
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33273501P | 2001-11-19 | 2001-11-19 | |
US60/332,735 | 2001-11-19 | ||
US10/108,640 | 2002-03-29 | ||
US10/108,640 US7125522B2 (en) | 2001-11-19 | 2002-03-29 | Multiwell apparatus |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2391071A1 CA2391071A1 (en) | 2003-05-19 |
CA2391071C true CA2391071C (en) | 2010-06-01 |
Family
ID=26806111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2391071A Expired - Fee Related CA2391071C (en) | 2001-11-19 | 2002-06-21 | Multiwell apparatus |
Country Status (5)
Country | Link |
---|---|
US (2) | US7125522B2 (en) |
EP (1) | EP1312414A3 (en) |
JP (1) | JP4233845B2 (en) |
AU (2) | AU2002301676B2 (en) |
CA (1) | CA2391071C (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7452712B2 (en) | 2002-07-30 | 2008-11-18 | Applied Biosystems Inc. | Sample block apparatus and method of maintaining a microcard on a sample block |
US6970240B2 (en) * | 2003-03-10 | 2005-11-29 | Applera Corporation | Combination reader |
DE10339158A1 (en) * | 2003-08-26 | 2005-04-07 | Evotec Technologies Gmbh | Handling device for closing elements for sample carriers such as titer plates and micro-titer plates comprises holding body for holding closing element on bearing surface, recess in bearing surface, and suction unit |
US20060029948A1 (en) * | 2003-09-19 | 2006-02-09 | Gary Lim | Sealing cover and dye compatibility selection |
US20050226780A1 (en) * | 2003-09-19 | 2005-10-13 | Donald Sandell | Manual seal applicator |
US20050221358A1 (en) * | 2003-09-19 | 2005-10-06 | Carrillo Albert L | Pressure chamber clamp mechanism |
US20050232818A1 (en) * | 2003-09-19 | 2005-10-20 | Donald Sandell | Single sheet seal applicator and cartridge |
US7460223B2 (en) * | 2003-09-19 | 2008-12-02 | Applied Biosystems Inc. | Inverted orientation for a microplate |
US20050226779A1 (en) | 2003-09-19 | 2005-10-13 | Oldham Mark F | Vacuum assist for a microplate |
US20050225751A1 (en) * | 2003-09-19 | 2005-10-13 | Donald Sandell | Two-piece high density plate |
US20060011305A1 (en) * | 2003-09-19 | 2006-01-19 | Donald Sandell | Automated seal applicator |
US7570443B2 (en) * | 2003-09-19 | 2009-08-04 | Applied Biosystems, Llc | Optical camera alignment |
US20060013984A1 (en) * | 2003-09-19 | 2006-01-19 | Donald Sandell | Film preparation for seal applicator |
WO2006110152A2 (en) * | 2004-06-18 | 2006-10-19 | North Dakota State University | Lined multi-well plates |
WO2008002562A2 (en) * | 2006-06-26 | 2008-01-03 | Applera Corporation | Compressible transparent sealing for open microplates |
WO2008002563A2 (en) * | 2006-06-26 | 2008-01-03 | Applera Corporation | Heated cover methods and technology |
DE202007002538U1 (en) * | 2007-02-21 | 2007-06-06 | Krebs, Torsten | Device for gasifying biological tissue and bacterial cultures, comprises a single-piece sample reception block exhibiting fluid supply arrangement, and gasifying head for supplying gasifying medium connected with the reception block |
CA2724106C (en) * | 2009-12-10 | 2018-04-17 | F. Hoffmann-La Roche Ag | Multiwell plate and lid |
CN103028456B (en) * | 2012-08-10 | 2014-10-08 | 卢瑾 | Detected specimen preserving and processing method and corresponding device |
GB2528671B (en) * | 2014-07-25 | 2018-11-14 | Rhys Jones Gethin | Container handling device |
EP3261761B1 (en) | 2015-02-27 | 2022-04-13 | Corning Incorporated | Fitted lid for multi-well plate |
US10227556B2 (en) * | 2015-09-04 | 2019-03-12 | Wayne State University | Cell culture devices for biomimetic and pathomimetic cell cultures |
WO2018144161A1 (en) * | 2017-01-31 | 2018-08-09 | Counsyl, Inc. | High throughput automatic diagnostic system for removing microplate lids |
WO2023141047A1 (en) * | 2022-01-20 | 2023-07-27 | Invitae Corporation | Device and method for placement and securement of film |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3997404A (en) * | 1974-06-07 | 1976-12-14 | Johnston Laboratories, Inc. | Method and apparatus for characterizing biologically active agents |
US4003713A (en) | 1975-08-14 | 1977-01-18 | Bowser Everett N | Multiple test tube evaporator |
US4657867A (en) * | 1984-11-01 | 1987-04-14 | Becton, Dickinson And Company | Multiwell tissue culture assembly with features for reduced media evaporation |
US4721679A (en) * | 1986-10-23 | 1988-01-26 | Yiu Felix H F | Tissue typing tray |
US5513768A (en) | 1992-07-20 | 1996-05-07 | Smith; James C. | Sealing cap for containers |
US5342581A (en) * | 1993-04-19 | 1994-08-30 | Sanadi Ashok R | Apparatus for preventing cross-contamination of multi-well test plates |
US5961926A (en) * | 1993-09-27 | 1999-10-05 | Packard Instrument Co., Inc. | Microplate assembly and method of preparing samples for analysis in a microplate assembly |
US5897838A (en) | 1994-03-11 | 1999-04-27 | Barrskogen, Inc. | Apparatus for rapid evaporation of aqueous solutions |
AU2122395A (en) * | 1994-04-04 | 1995-10-23 | Ashok R. Sanadi | Method and apparatus for preventing cross-contamination of multi-well test plates |
US5817510A (en) | 1995-02-24 | 1998-10-06 | Xechem International, Inc. | Device and method for evaluating microorganisms |
US5604130A (en) * | 1995-05-31 | 1997-02-18 | Chiron Corporation | Releasable multiwell plate cover |
US5842573A (en) * | 1997-03-11 | 1998-12-01 | Halvorsen; Yuan-Di C. | Method of transporting cells and kit useful therefor |
US5817509A (en) | 1997-03-19 | 1998-10-06 | Becton Dickinson And Company | Culture vessel assembly |
US5851346A (en) * | 1997-05-29 | 1998-12-22 | Beckman Instruments, Inc. | Apparatus for sealing containers |
JP3308209B2 (en) * | 1998-05-09 | 2002-07-29 | アトム興産株式会社 | Sealing device for multi-well plate |
US6436351B1 (en) * | 1998-07-15 | 2002-08-20 | Deltagen Research Laboratories, L.L.C. | Microtitre chemical reaction system |
WO2000013761A1 (en) * | 1998-09-04 | 2000-03-16 | Vertex Pharmaceuticals Incorporated | Vortex evaporator |
GB2348826B (en) * | 1999-04-17 | 2003-03-26 | Michael Cole | Evaporation of liquids |
EP1332086A1 (en) | 2000-06-30 | 2003-08-06 | Incyte Genomics, Inc. | Microplate sealer |
US6939516B2 (en) | 2000-09-29 | 2005-09-06 | Becton, Dickinson And Company | Multi-well plate cover and assembly adapted for mechanical manipulation |
US6896848B1 (en) * | 2000-12-19 | 2005-05-24 | Tekcel, Inc. | Microplate cover assembly |
US6450012B1 (en) * | 2001-04-30 | 2002-09-17 | Mocon, Inc. | Multi-port gas leakage measurement fixture |
US6485918B1 (en) * | 2001-07-02 | 2002-11-26 | Packard Bioscience Corporation | Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate |
JP2003149249A (en) * | 2001-08-01 | 2003-05-21 | Becton Dickinson & Co | Multiwell plate cover and assembly suitable for mechanical control |
-
2002
- 2002-03-29 US US10/108,640 patent/US7125522B2/en not_active Expired - Lifetime
- 2002-06-21 CA CA2391071A patent/CA2391071C/en not_active Expired - Fee Related
- 2002-07-04 EP EP02014755A patent/EP1312414A3/en not_active Ceased
- 2002-10-29 AU AU2002301676A patent/AU2002301676B2/en not_active Ceased
- 2002-11-06 JP JP2002323010A patent/JP4233845B2/en not_active Expired - Fee Related
-
2006
- 2006-08-23 US US11/466,577 patent/US7572411B2/en not_active Expired - Fee Related
-
2009
- 2009-01-30 AU AU2009200345A patent/AU2009200345C1/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP1312414A2 (en) | 2003-05-21 |
US20060280654A1 (en) | 2006-12-14 |
AU2002301676B2 (en) | 2008-12-11 |
AU2009200345A1 (en) | 2009-02-19 |
EP1312414A3 (en) | 2004-03-17 |
US7572411B2 (en) | 2009-08-11 |
JP4233845B2 (en) | 2009-03-04 |
JP2003227839A (en) | 2003-08-15 |
CA2391071A1 (en) | 2003-05-19 |
US7125522B2 (en) | 2006-10-24 |
AU2009200345B2 (en) | 2011-03-10 |
US20030096427A1 (en) | 2003-05-22 |
AU2009200345C1 (en) | 2011-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20180621 |