CA2416546A1 - Probe and apparatus for measuring cerebral hemodynamics and oxygenation - Google Patents
Probe and apparatus for measuring cerebral hemodynamics and oxygenation Download PDFInfo
- Publication number
- CA2416546A1 CA2416546A1 CA002416546A CA2416546A CA2416546A1 CA 2416546 A1 CA2416546 A1 CA 2416546A1 CA 002416546 A CA002416546 A CA 002416546A CA 2416546 A CA2416546 A CA 2416546A CA 2416546 A1 CA2416546 A1 CA 2416546A1
- Authority
- CA
- Canada
- Prior art keywords
- probe
- oxygenation
- cerebral
- skull
- coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002490 cerebral effect Effects 0.000 title abstract 5
- 239000000523 sample Substances 0.000 title abstract 3
- 238000006213 oxygenation reaction Methods 0.000 title abstract 2
- 230000000004 hemodynamic effect Effects 0.000 title 1
- 239000011248 coating agent Substances 0.000 abstract 3
- 238000000576 coating method Methods 0.000 abstract 3
- 210000003625 skull Anatomy 0.000 abstract 3
- 241001269524 Dura Species 0.000 abstract 1
- 210000004289 cerebral ventricle Anatomy 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6864—Burr holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
- A61B5/031—Intracranial pressure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Neurology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
The invention relates to a probe (1) and an apparatus for cerebral diagnostics and therapy, in particular for measuring absolute values of regional cerebral flow (CBF) and cerebral oxygenation. The probe is inserted through a burr hole in the skull and comprises illuminating means, light receiving means and a coating encapsulating said illuminating means and said light receiving means.
The coating has a longitudinal shape and is adapted to fit through a burr hole in the skull. Said coating is further adapted to slide between the skull and the dura, to be inserted into the ventricular system, and/or to be inserted into the cerebral tissue.
The coating has a longitudinal shape and is adapted to fit through a burr hole in the skull. Said coating is further adapted to slide between the skull and the dura, to be inserted into the ventricular system, and/or to be inserted into the cerebral tissue.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00115732 | 2000-07-21 | ||
EP00115732.0 | 2000-07-21 | ||
PCT/EP2001/008331 WO2002007592A1 (en) | 2000-07-21 | 2001-07-19 | Probe and apparatus for measuring cerebral hemodynamics and oxygenation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2416546A1 true CA2416546A1 (en) | 2002-01-31 |
CA2416546C CA2416546C (en) | 2007-12-18 |
Family
ID=8169324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002416546A Expired - Lifetime CA2416546C (en) | 2000-07-21 | 2001-07-19 | Probe and apparatus for measuring cerebral hemodynamics and oxygenation |
Country Status (9)
Country | Link |
---|---|
US (1) | US7120481B2 (en) |
EP (2) | EP1301119B1 (en) |
JP (1) | JP3718500B2 (en) |
AT (1) | ATE297685T1 (en) |
AU (1) | AU2001281996A1 (en) |
CA (1) | CA2416546C (en) |
DE (1) | DE60111531T2 (en) |
ES (1) | ES2242761T3 (en) |
WO (1) | WO2002007592A1 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10315574A1 (en) * | 2003-04-05 | 2004-10-28 | ETH Zürich | Device for determining blood flow in an organ |
EP1547515A1 (en) * | 2003-12-22 | 2005-06-29 | Barts and The London National Health Service Trust | Optical fibre catheter pulse oximeter |
US7570979B2 (en) * | 2004-03-30 | 2009-08-04 | Philip George Cooper | Methods and apparatus for patient monitoring |
JP3721408B2 (en) | 2004-04-06 | 2005-11-30 | 国立大学法人 岡山大学 | Brain ischemia monitoring monitor |
US7819812B2 (en) | 2004-12-15 | 2010-10-26 | Neuropace, Inc. | Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders |
US7341562B2 (en) * | 2004-12-15 | 2008-03-11 | Neuropace, Inc. | Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders |
US9380966B2 (en) * | 2007-06-22 | 2016-07-05 | Vioptix, Inc. | Tissue retractor oximeter |
US20090204009A1 (en) * | 2008-02-07 | 2009-08-13 | Los Alamos National Security | Medical device system and related methods for diagnosing abnormal medical conditions based on in-vivo optical properties of tissue |
US8452402B2 (en) * | 2008-04-23 | 2013-05-28 | Medtronic, Inc. | Optical sensing device for use in a medical device |
US9326711B2 (en) * | 2008-06-30 | 2016-05-03 | Medtronic, Inc. | Optical perfusion sensor detector |
US10058274B2 (en) * | 2008-06-30 | 2018-08-28 | Medtronic, Inc. | Tissue perfusion sensor control |
US8086302B2 (en) * | 2008-06-30 | 2011-12-27 | Medtronic, Inc. | Cardiac signal sensor control based on perfusion sensing |
US20100022861A1 (en) * | 2008-07-28 | 2010-01-28 | Medtronic, Inc. | Implantable optical hemodynamic sensor including an extension member |
US20100022856A1 (en) * | 2008-07-28 | 2010-01-28 | Medtronic, Inc. | Implantable optical hemodynamic sensor including light transmission member |
CH699338B1 (en) * | 2008-08-06 | 2012-01-13 | Carag Ag | Device for measuring the blood flow in a body tissue. |
EP2168475B1 (en) * | 2008-09-25 | 2012-03-07 | NeMoDevices AG | Device for diagnosis and/or therapy of physiological characteristics of a selected portion of a body by optical reflectance or optical transmission |
KR101034798B1 (en) * | 2009-03-18 | 2011-05-17 | 한국과학기술연구원 | Apparatus for detecting brain conditions |
US9737213B1 (en) * | 2009-03-24 | 2017-08-22 | Vioptix, Inc. | Using an oximeter probe to detect intestinal ischemia |
CH704900A1 (en) | 2011-05-05 | 2012-11-15 | Nemo Devices Ag | Measuring device for measuring cerebral parameters. |
US10064554B2 (en) | 2011-12-14 | 2018-09-04 | The Trustees Of The University Of Pennsylvania | Fiber optic flow and oxygenation monitoring using diffuse correlation and reflectance |
US10028682B2 (en) | 2012-10-12 | 2018-07-24 | University Of Virginia Patent Foundation | Oxidation measurement system and related method thereof |
CH707194A1 (en) | 2012-11-06 | 2014-05-15 | Nemodevices Ag | Measuring device for determining cerebral parameters. |
FI2999402T3 (en) | 2013-05-22 | 2023-03-19 | Luciole Medical AG | Measurement system and method for measuring parameters in a body tissue |
US10912504B2 (en) | 2014-01-14 | 2021-02-09 | Canon U.S.A., Inc. | Near-infrared spectroscopy and diffuse correlation spectroscopy device and methods |
US10357188B2 (en) * | 2014-10-15 | 2019-07-23 | Koninklijke Philips N.V. | Flexible optical source for pulse oximetry |
US10716499B1 (en) * | 2015-03-24 | 2020-07-21 | Zoll Medical Corporation | Physiological monitoring by optical spectroscopy |
RU2727237C2 (en) | 2015-05-29 | 2020-07-21 | Караг Аг | Catheter for measuring blood flow in body tissue |
EP3360464A1 (en) * | 2017-02-10 | 2018-08-15 | Carag AG | Apparatus and method for measuring the blood oxygen saturation in a subject's tissue |
CN108143426A (en) * | 2017-12-26 | 2018-06-12 | 成都拓蓝医疗技术有限公司 | Blood oxygen of brain saturation degree precisely monitors sensor and its monitoring method |
EP3758588A4 (en) * | 2018-03-01 | 2021-12-29 | Archeoptix Biomedical Inc. | System for intracranial imaging and treatment |
US10973579B2 (en) | 2018-12-28 | 2021-04-13 | Industrial Technology Research Institute | Optical system |
KR102279322B1 (en) * | 2019-04-08 | 2021-07-21 | 한양대학교 산학협력단 | Multimodal diagnostic and therapeutic catheter and catheter system |
DE102019122096A1 (en) | 2019-08-16 | 2021-02-18 | Endress+Hauser Conducta Gmbh+Co. Kg | Optochemical sensor and method |
US11730373B2 (en) * | 2020-04-20 | 2023-08-22 | Covidien Lp | Sensor with variable depth interrogation |
EP4173551A4 (en) * | 2020-06-29 | 2023-12-20 | Ant5 Co., Ltd. | Subdural sensor |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4281645A (en) * | 1977-06-28 | 1981-08-04 | Duke University, Inc. | Method and apparatus for monitoring metabolism in body organs |
DE3475467D1 (en) | 1983-03-10 | 1989-01-12 | Shionogi & Co | Photoelectric brain scanner and its use |
US4784150A (en) * | 1986-11-04 | 1988-11-15 | Research Corporation | Surgical retractor and blood flow monitor |
JPH06103257B2 (en) * | 1988-12-19 | 1994-12-14 | 大塚電子株式会社 | Method and apparatus for measuring absorption coefficient of substance using light scattering |
US5024226A (en) * | 1989-08-17 | 1991-06-18 | Critikon, Inc. | Epidural oxygen sensor |
US5193544A (en) | 1991-01-31 | 1993-03-16 | Board Of Trustees Of The Leland Stanford Junior University | System for conveying gases from and to a subject's trachea and for measuring physiological parameters in vivo |
US5218962A (en) | 1991-04-15 | 1993-06-15 | Nellcor Incorporated | Multiple region pulse oximetry probe and oximeter |
US5632273A (en) * | 1994-02-04 | 1997-05-27 | Hamamatsu Photonics K.K. | Method and means for measurement of biochemical components |
US5579774A (en) * | 1994-03-07 | 1996-12-03 | Camino Neurocare, Inc. | Method and apparatus for monitoring local cerebral physiology |
US5685313A (en) | 1994-05-31 | 1997-11-11 | Brain Monitor Ltd. | Tissue monitor |
DE4445683A1 (en) * | 1994-12-21 | 1996-06-27 | Boehringer Mannheim Gmbh | Method for examining a scattering medium with intensity-modulated light |
US5524617A (en) * | 1995-03-14 | 1996-06-11 | Nellcor, Incorporated | Isolated layer pulse oximetry |
US6095974A (en) * | 1995-07-21 | 2000-08-01 | Respironics, Inc. | Disposable fiber optic probe |
JP3426847B2 (en) | 1996-05-14 | 2003-07-14 | アルプス電気株式会社 | Coordinate input device |
US6166806A (en) | 1995-09-29 | 2000-12-26 | Tjin; Swee Chuan | Fiber optic catheter for accurate flow measurements |
GB2333152B (en) | 1998-01-08 | 2002-11-06 | Diametrics Medical Ltd | Method and apparatus for monitoring cerebral physiology |
US6353226B1 (en) * | 1998-11-23 | 2002-03-05 | Abbott Laboratories | Non-invasive sensor capable of determining optical parameters in a sample having multiple layers |
US6615061B1 (en) * | 1998-11-23 | 2003-09-02 | Abbott Laboratories | Optical sensor having a selectable sampling distance for determination of analytes |
US6533733B1 (en) * | 1999-09-24 | 2003-03-18 | Ut-Battelle, Llc | Implantable device for in-vivo intracranial and cerebrospinal fluid pressure monitoring |
-
2001
- 2001-07-19 US US10/333,262 patent/US7120481B2/en not_active Expired - Lifetime
- 2001-07-19 AU AU2001281996A patent/AU2001281996A1/en not_active Abandoned
- 2001-07-19 JP JP2002513337A patent/JP3718500B2/en not_active Expired - Lifetime
- 2001-07-19 EP EP01960517A patent/EP1301119B1/en not_active Expired - Lifetime
- 2001-07-19 EP EP04105664A patent/EP1504715A1/en not_active Ceased
- 2001-07-19 DE DE60111531T patent/DE60111531T2/en not_active Expired - Lifetime
- 2001-07-19 ES ES01960517T patent/ES2242761T3/en not_active Expired - Lifetime
- 2001-07-19 WO PCT/EP2001/008331 patent/WO2002007592A1/en active IP Right Grant
- 2001-07-19 CA CA002416546A patent/CA2416546C/en not_active Expired - Lifetime
- 2001-07-19 AT AT01960517T patent/ATE297685T1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1301119A1 (en) | 2003-04-16 |
DE60111531D1 (en) | 2005-07-21 |
AU2001281996A1 (en) | 2002-02-05 |
EP1504715A1 (en) | 2005-02-09 |
JP2004504092A (en) | 2004-02-12 |
US20040039270A1 (en) | 2004-02-26 |
EP1301119B1 (en) | 2005-06-15 |
WO2002007592A1 (en) | 2002-01-31 |
ATE297685T1 (en) | 2005-07-15 |
CA2416546C (en) | 2007-12-18 |
JP3718500B2 (en) | 2005-11-24 |
ES2242761T3 (en) | 2005-11-16 |
US7120481B2 (en) | 2006-10-10 |
DE60111531T2 (en) | 2006-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20210719 |