CA2437029A1 - Method and apparatus for localized low energy photon therapy (lept) - Google Patents

Method and apparatus for localized low energy photon therapy (lept) Download PDF

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CA2437029A1
CA2437029A1 CA002437029A CA2437029A CA2437029A1 CA 2437029 A1 CA2437029 A1 CA 2437029A1 CA 002437029 A CA002437029 A CA 002437029A CA 2437029 A CA2437029 A CA 2437029A CA 2437029 A1 CA2437029 A1 CA 2437029A1
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optical
pulse repetition
continuous wave
repetition rate
probe
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CA2437029C (en
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Norman Salansky
Natalia Filonenko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A61N2005/0652—Arrays of diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body

Abstract

An apparatus for treating a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters. The apparatus has a power source, a central microprocessor with stored optical parameter protocols and wireless probes to receive the protocols and to generate and transmit the light. The invention also relates to a method for stimulating healing of a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters.

Claims (73)

1. An apparatus for treating a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters, comprising:
(a) a power source for providing power to a central microprocessor;
(b) a central microprocessor having stored optical parameter protocols suitable for treating a range of disorders of biological tissue and means for selecting one or more stored optical parameter protocols for the disorder to be treated;
(c) at least one optical probe, having a microprocessor in communication with the central microprocessor, to receive the selected optical parameter protocol, said probe containing an optical source for generating a beam of light having the selected optical parameter protocol and for directing the beam of light to the biological tissue to be treated ; and (d) communication means for transmitting the optical parameter protocol from the central microprocessor to the heads.
2. The apparatus of claim 1 wherein the beam of light having the selected optical parameter protocol is substantially monochromatic and has a wavelength of from 400 to 2,000 nm.
3 The apparatus of claim 2 wherein the beam of light has a wavelength in the range of from 630 to 700 nm, from 740 to 760 nm, or from 800 to 1,100 nm.
4. The apparatus of claim 1 wherein the optical source is a laser, laser diode, light emitting or superluminous diode, which provides substantially monochromatic light.
5. The apparatus of claim 4 including means for operating the optical source in pulsed mode with a pulse repetition rate in a range of from 0 to 200 Hz.
6. The apparatus of claim 1 wherein the optical parameters are selected from the group comprising dose, intensity, frequency, pulse duration, wavelength, power, monochromaticity, intensity modulation with specific endogenous frequencies, three-dimensional photon distribution.
7. The apparatus of claim 1 wherein the communication means are wireless.
8. The apparatus of claim 7 including a plurality of probes for each central microprocessor, each probe being capable, independently of the remaining probes, of receiving one or more optical parameter protocols from said central microprocessor.
9. The apparatus of claim 1, 7 or 8 wherein said communication means includes a telephone link.
10. The apparatus of claim 1 further comprising means for monitoring the condition of the mammal and providing feedback to the central microprocessor to adjust the selected optical parameter protocol including adjustment of the phase of stimulation in respect to the endogenous rhythm phase based on the condition of the mammal.
11. The apparatus of claim 8 wherein the means for monitoring the condition of the mammal is on-line EEG, EMG, ECG, or a respirator.
12. The apparatus of claim 1 wherein said probe includes a matrix of optical sources arranged in a square or rectangular pattern, to provide three dimensional photon distribution in the affected area.
13. The apparatus of claim 1 wherein said probe includes a matrix of optical sources arranged in a circular pattern.
14. The apparatus of claim 13 wherein said circular pattern provides photons in an area (R+1)2/R2, where R is the radius of an affected area of said biological tissue.
15. The apparatus of claim 1 wherein said optical probe includes two sets of optical sources, one set comprising a single light source arranged on a stalk, and the other comprising a matrix of optical sources arranged on a face of said optical head.
16. The apparatus of claim 1 wherein said optical probe includes a flexible body capable of adapting to the contours of a portion of a patient to be treated, and a plurality of said optical sources arranged on said flexible body.
17. The apparatus of claim 1 wherein said optical probe includes a body arranged in a circular configuration and adapted to fit on the finger of a patient, said body having an inner surface, and at least one optical source arranged on said inner surface.
18. An apparatus for treating dermatological, musculoskeletal, soft tissue or neurological disorders of a biological tissue with non-ionizing low energy light having selected optical parameters, comprising:

(a) a power source for providing power to a central microprocessor;
(b) a central microprocessor having stored optical parameter protocols suitable for treating a range of said disorders of biological tissue and means for selecting one or more stored optical parameter protocols for the disorder to be treated, said parameters including wavelength, power, intensity and dose;
(c) an optical probe, having a microprocessor in communication with the central microprocessor, to receive the selected optical parameter protocol, said probe containing an optical parameter protocol said probe containing an optical source for generating a beam of light having the selected optical parameter protocol and for directing the beam of light to the biological tissue to be treated;
(d) said optical source including an array of light emitting sources, all of said sources when activated producing substantially monochromatic non-ionizing light having a selected wavelength in the range of from 630 to 2000 nm and a bandwidth not exceeding substantially 30 to 40 nm, and each of said sources providing light of the same said selected wavelength and no other wavelength;
(e) said optical source further including a control circuit for activating selected ones of said light emitting sources to produce a three dimensional light distribution of said tissue;
(f) said protocols including a protocol for providing said beam of light as said substantially monochromatic non-ionizing light to stimulate said tissue;
(g) communication means for transmitting the optical parameter protocol from the central microprocessor to said at least one probe; and (h) said probe containing said protocol only for said selected wavelength and not containing any protocol for any other wavelength.
19. The apparatus of claim 18 wherein the beam of light has a wavelength in the range of from 630 to 700 nm, from 740 to 760 nm, or from 800 to 1,100 nm.
20. The apparatus of claim 18 wherein the optical source is a laser, laser diode, light emitting or superluminous diode, which provides substantially monochromatic light.
21. The apparatus of claim 20 including means for operating the optical source in pulsed mode with a pulse repetition rate in a range of from 0 to 200 Hz.
22. The apparatus of claim 18 wherein the optical parameters are selected from the group comprising dose, intensity, frequency, pulse duration, wavelength, power, monochromaticity, intensity modulation with specific endogenous frequencies, three-dimensional photon distribution.
23. The apparatus of claim 18 wherein the communication means are wireless.
24. The apparatus of claim 23 including a plurality of probes for each central microprocessor, each probe being capable, independently of the remaining probes, of receiving one or more optical parameter protocols from said central microprocessor.
25. The apparatus of claim 18, 23, or 24 wherein said communication means includes a telephone link between said central microprocessor and said at least one probe, and a communication interface between said telephone link and said at least one probe, said telephone link including a modem, so that said at least one probe may receive said optical parameter protocol remotely over said telephone link.
26. The apparatus of claim 18 further comprising means for monitoring the condition of the mammal and providing feedback to the central microprocessor to adjust the selected optical parameter protocol including adjustment of the phase of stimulation in respect to the endogenous rhythm phase based on the condition of the mammal.
27. The apparatus of claim 26 wherein the means for monitoring the condition of the mammal is on-line EEG. EMG, ECG, a respirator, or chemoluminescence.
28. The apparatus of claim 18 wherein said light emitting sources are arranged in a square or rectangular pattern, to provide said three dimensional photon distribution in the affected area.
29. The apparatus of claim 18 wherein said light emitting sources are arranged in a circular pattern.
30. The apparatus of claim 29 wherein said circular pattern provides photons in an area (R+1)2/R2, where R is the radius of an affected area of said biological tissue.
31. The apparatus of claim 18 wherein said optical probe includes two sets of light emitting sources, one set comprising a single light source arranged on a stalk, and the other comprising a matrix of light emitting sources arranged on a face of said optical probe.
32. The apparatus of claim 18 wherein said light emitting probe includes a flexible body capable of adapting to the contours of a portion of a patient to be treated, and a plurality of said optical sources arranged on said flexible body.
33. The apparatus of claim 18 wherein said optical probe includes a body arranged in a circular configuration and adapted to fit on the finger of a patient, said body having an inner surface, and a plurality of light emitting sources arranged on said inner surface.
34. The apparatus of claim 18 wherein said probe contains an optical parameter protocol such that said that said probe provides a dose of from 0.05 to 10 J/cm2, an intensity of from 0.2 to 100 mW/cm2, a wavelength of from 630 to 2,000 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz,1 to 1.2 Hz and 1 to 5 Hz.
35. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 0.05 to 0.2 J/cm2, a wavelength of from 630 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.
36. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such That said probe provides a dose of from 2.0 to 5.0 J/cm2, a wavelength of from 630 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.
37. The apparatus of claim 18 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 3.0 to 9.0 J/cm2, an intensity of from 50.0 to 80 mW/cm2 and a wavelength of from 630 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, to 1.2 Hz, and 1 to 5 Hz.
38. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 0.1 to 9.0 J/cm2, an intensity o from 300 to 600 mW/cm2 and a wavelength of from 800 to 1,100 nm in a continuous wave (CW) mode or pulse repetition rate of 10 Hz or from 50 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of 0.3 and/or 1.2 Hz.
39. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 2 to 5 J/cm2, an intensity of from 10 to 30 mW/cm2 and a wavelength of from 630 to 700 nm.
40. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 3 to 7 J/cm2 or 4 to 25 J/cm2, an intensity of from 10 to 40 mW/cm2 to 60 to 100 mW/cm2 or 300-600 mW/cm2 or 1000 to 5000 mW/cm2 and a wavelength of from 800 to 1100 nm.
41. The apparatus of claim 34 wherein said probe contains an optical parameter protocol such that said probe provides a dose of from 4 to 9 J/cm2, an intensity of from 20 to 60 mW/cm2 and a wavelength of from 630 to 700 nm.
42. The apparatus of claim 18 wherein said control circuit includes a circuit for activating said light emitting sources with a selected pulse repetition rate.
43. The apparatus of claim 18 wherein said optical parameter protocol in said probe is selected according to the color of skin of the patient to be treated.
44. A method for programming apparatus for treating a disorder of biological tissue by stimulating the biological tissue with light having selected optical parameters, comprising:
(a) storing in a central memory a plurality of optical parameter protocols suitable for treating a range of disorders of biological tissue, (b) providing a probe unit containing at least one optical source for generating a beam of light, (c) and transferring to said probe unit from the central memory at least one desired optical parameter protocol, so that said probe unit may on operation apply the desired optical parameter protocol to the tissue to be treated.
45. A method according to claim 44 and including the step of transferring said optical parameter protocol from said central memory to said probe unit by wireless.
46. A method according to claim 44 and including the step of transferring said optical parameter protocol from said central memory to said probe unit by telephone link.
47. A method according to claim 44 and including the step of transferring different optical parameter protocols to a plurality of probe units from a common central memory.
48. A method according to claim 47 wherein, after each probe unit has received said at least one optical parameter protocol from said central memory, such probe unit is removed to a location remote from such central memory, for use.
49. A method according to claim 48 wherein said location is a patient's home.
50. A method for stimulating healing of a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters, comprising:
(a) providing a central microprocessor having stored optical parameter protocols suitable for treating a range of disorders of biological tissue;
(b) selecting one or more stored optical parameter protocols for the disorder to be treated;
(c) generating a beam of light having the selected optical parameter protocol and directing the beam of light to the biological tissue to be treated.
51. A method of stimulating healing of a lesion in a mammal, comprising: irradiating the lesion with a substantially monochromatic beam of light having predetermined optical parameters, wherein the predetermined optical parameters include a dose of from 0.05 to 10 J/cm2, an intensity of from 0.2 to 100 mW/cm2, a wavelength of from 400 to 2,000 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 2 to 5 Hz.
52. The method of claim 51 wherein the lesion is an ulcer or a wound and the selected optical parameters include a dose of from 0.05 to 0.2 J/cm2, a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.
53. The method of claim 51 wherein the lesion is an ulcer or wound in acute inflammatory condition and the selected optical parameters include a dose of from 2.0 to 5.0 J/cm2, an intensity of from 10.0 to 30 mW/cm2, and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz., 1 to 1.2 Hz, and 1 to 5 Hz.
54. The method of claim 51 wherein the lesion is an infected wound and the selected optical parameters include a dose of from 3.0 to 9.0 J / cm2, an intensity of from 50.0 to 80 mW / cm2 and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, to 1.2 Hz, and 1 to 5 Hz.
55. The method of claim 51 wherein the lesion is an ulcer or a wound in the area with impaired microcirculation and the selected optical parameters include a dose of from 0.1 to 9.0 J/cm2, an intensity of from 300 to 600 mW/cm2 and a wavelength of from 800 to 1,100 nm in a continuous wave (CW) mode or with pulse repetition rate of 10 Hz or from 50 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of 0.3 and/or 1.2 Hz and the area to be treated is the skin surrounding the lesion.
56. The method of claim 51 where the lesion is an ulcer or wound and the selected optical parameters include a suitable combination of the optical parameters of claims 52, 53, 54 and 55 depending on the ulcer or wound condition or stage.
57. The method of claim 51 wherein the lesion is a post-surgical scar in an acute inflammatory condition and the selected optical parameters include a dose of from 2 to 5 J/cm2, an intensity of from 10 to 30 mW / cm2 and a wavelength of from 600 to 700 nm.
58. The method of claim 51 wherein the lesion is a post-surgical scar in a sub-acute inflammatory condition and the selected optical parameters include a dose of from 3 to 7 J/cm2 or 4 to 25 J/cm2, an intensity of from 10 to 40 mW/cm2 or 60 to 100 mW/cm2 or 300-600 mW/cm2 or 1000 to 5000 mW/cm2 and a wavelength of from 800 to 1100 nm.
59. The method of claim 51 wherein the lesion is induced by Herpes Simplex virus (cold sore) or acne and the selected optical parameters include a dose of from 4 to 9 J/cm2, an intensity of from 20 to 60 mW / cm2 and a wavelength of from 630 to 700 nm.
60. A method of stimulating healing of acute and chronic musculo-skeletal and neuromuscular pathological conditions in soft tissue (muscle, tendons, ligaments, nerves, etc.), bones and joints in a mammal, comprising: irradiating the affected area with a substantially monochromatic beam of light having predetermining optical parameters, wherein the predetermined optical parameters include a dose of from 0.1 to 150 J/cm2, an intensity of from 1 to 10000 mW/cm2, a wavelength of from 400 to 2000 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, or from 1000 to 10000 Hz, optional modulation frequencies of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz, and selected phases of stimulation in respect to the phase of endogenous rhythm of from 0 to 90°.
61. A method of stimulating healing of post-traumatic conditions in soft tissue (skin, muscles, tendons, ligaments, nerves, etc.), bones and joints in a mammal comprising: irradiating the traumatized area or selected points in the affected area with a substantially monochromatic beam of light having predetermined optical parameters wherein the predetermined optical parameters include a dose of from 3 to 100 J/cm2, an intensity of from 1 to 5000 mW/cm2 and a wavelength of from 400 to 2000 nm, and a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz.
62. The methods of claim 60 or 61 wherein the condition to be treated is in the acute stage of inflammatory condition and the selected optical parameters include doses of from 3 to 10 J/cm2, intensities of from 10 to 40 mW/cm2 and 30 to 100 mW/cm2 and wavelengths of from 630 to 700 nm and 800 to 1100 nm, and a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz.
63. The method of claim 60 or 61 wherein the condition to be treated is accompanied by hematoma, bruise and the selected optical parameters for hematoma, bruise healing acceleration include doses of from 5 to 14 J/cm2, intensities of from 20 to 50 J/cm2, a wavelength of from 630 to 700 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz,1 to 1.2 Hz and 1 to 5 Hz.
64. The method of claim 60 or 61 wherein the condition to be treated is in the sub-acute stage of inflammatory condition and the selected optical parameters include doses of from 3 to 7 J/cm2 and 4 to 25 J/cm2, intensities of from 10 to 40 mW/cm2 and 60 to 100 mW/cm2 and 300 to 600 mW/cm2 and 1000 to 5000 mW/cm2 and a wavelength of from 800 to 1100 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz.
65. The method of claim 60 or 61 wherein the condition to be treated is in the stage of regeneration of tissue, normalization of function and the selected optical parameters include doses of from 3 to 5 J/cm2 and 4 to 25 J/cm2, intensities of from 60 to 100 mW/cm2 and 300 to 600 mW/cm2 and 1000 to 5000 mW/cm2 and a wavelength of from 800 to 1100 nm, and a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz.
66. The method of stimulating healing of a chronic inflammation in soft tissue and/or joints in a flare-up stage of pre-existing musculo-skeletal or neuromuscular pathological conditions (e.g. tendinitis, bursitis, epicondylitis, arthritis, rheumatoid arthritis, ankylosing spondylitis, repetitive strain injuries, etc.) in a mammal comprising:
(a) irradiating the affected area with a substantially monochromatic beam of light having predetermined optical parameters wherein the predetermined optical parameters include a dose of from 0.1 to 0.5 J/cm2, an intensity of from 1 to 10 mW / cm2, a wavelength of from 630 to 700 nm or 800 to 1100 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz.
(b) and in addition, irradiating selected points or areas on the body with a substantially monochromatic beam of light having predetermined optical parameters wherein the predetermined optical parameters include a dose of from 0.1 to 0.6 J/cm2 and 1 to 5 J/cm2, intensities of from 1 to 10 m W / c m 2, 10 to 30 mW / cm2, 100 to 300 mW / cm2, wavelengths of from 630 to 700 nm and 800 to 1100 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz,1 to 1.2 Hz, and 1 to 5 Hz.
67. The method of stimulating healing of chronic inflammation in soft tissue and/or joint sin a mammal with chronic musculo-skeletal or neuro-muscular conditions without flare-up (e.g. tendinitis, bursitis, epicondylitis, arthritis, rheumatoid arthritis, spurs, repetitive strain injuries, etc.) comprising: irradiating the affected area with a substantially monochromatic beam of light having predetermined optical parameters wherein the predetermined optical parameters include a dose of from 2 to 9 J/cm2, 3 to 25 J/cm2, 25 to 100 J/cm2, intensities of from 5 to 30 mW/cm2, 10 to 40 mW/cm2, 60 to 100 mW/cm2, 300 to 600 mW/cm2, 1000 to 5000 mW/cm2, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 hz and 1 to 5 Hz.
68. The method of stimulating healing of inflammatory degenerative joint diseases (arthritis, rheumatoid arthritis, degenerative disk disease, ankylosing spondylitis, repetitive strain injuries, etc.) in mammals, comprising: irradiating the affected area and/or selected points in the affected area with a substantially monochromatic beam of light having predetermined optical parameters wherein the predetermined optical parameters include doses of from 0.1 to 0.5 J/cm2, 2 to 9 J/cm2, 3 to 25 J/cm2, 25 to 100 J/cm2, intensities of from 1 to 10 mW/cm2, 10 to 30 mW/cm2, 60 to 100 mW/cm2, 300 to 600 mW/cm2 and 1000 to 5000 mW/cm2, wavelengths of from 630 to 700 nm and 800 to 1100 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, modulation frequencies of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz, and in addition, irradiating selected points or areas on the body with a substantially monochromatic beam of light having predetermined optical parameters, wherein the predetermined optical parameters include doses of from 0.1 to 0.5 J/cm2, 1 to 5 J/cm2, intensities of from 1 to 10 mW/cm2 and 100 to 300 mW/cm2, wavelengths of from 630 to 700 nm and 800 to 1100 nm, a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz,1 to 1.2 Hz, and 1 to 5 Hz.
69. The method of claim 60 wherein musculo-skeletal or neuromuscular pathological condition is accompanied by muscle spasm (myofascial pain, fibromyalgia, repetitive strain injuries or cumulative trauma disorders, sports injuries, etc.) and the selected optical parameters for muscle spasm relief include doses of from 0.1 to 0.5 J/cm2, 3 to 5 J/cm2. 4 to 25 J/cm2 and 25 to 100 J/cm2, intensities of from 1 to 10 mW / cm2, 1 to 40 mW / cm2, 60 to 100 mW / cm2, 300 to 600 mW / cm2 and 1000 to 10000 mW/cm2, wavelengths of from 630 to 700 nm and 800 to 1100 nm, continuous wave mode or pulse repetition rates of from 0 to 200 Hz and 1000 to 10000 Hz.
70. The method of claim 60 where musculo-skeletal or neuromuscular pathological conditions are accompanied by pain, tender and trigger points, (myofascial pain, fibromyalgia, repetitive strain injuries or cumulative trauma disorders, sports injuries, tendinitis, epicondylitis, bursitis, spurs, etc.) and the selected optical parameters for pain relief, tender and trigger point therapy include a dose of from 4 to 150 J/cm2, intensities of from 60 to 100 mW/cm2, 300 to 600 mW/cm2, 800 to 10000 mW/cm2, a wavelength of from 630 to 1100 nm, a continuous wave mode or a pulse repetition rate of from 50 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz and 1 to 5 Hz.
71. The method of claim 60 or 61 where the condition to be treated is accompanied by swelling, edema, and pain (e.g. post-traumatic, post-surgical complications, arthritis) and the selected optical parameters for swelling, edema and pain relief and lymphatic drainage activation include doses of from 5 to 14 J/cm2, 25 to 100 J/cm2, intensities of from 10 to 40 mW / cm2, 300 to 600 mW / cm2. And from 1000 to 5000 mW / cm2, wavelengths of from 630 to 700 nm and 800 to 1100 nm, continuous wave mode or pulse repetition rates of from 0 to 200 Hz and 1000 to 10000 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.
72. The method of claim 60 where said neuromuscular pathological condition is carpal tunnel syndrome and the selected optical parameters include doses of from 0.05 to 0.3 J/cm2, 0.2 to 4.0 J/cm2, 5 to 10 J/cm2, and 25 to 150 J/cm2, intensities of from 1 to 10 mW/cm2, 60 to 100 mW/cm2, 300 to 600 mW/cm2, 1,000 to 10,000 mW/cm2, continuous wave mode or pulse repetition rates of from 0 to 200 Hz and 1000 to 10000 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz and 1 to Hz.
73. The method of claim 60 where said neuromuscular pathological conditions are neuritis, neuralgia, trigeminal neuralgia and the selected optical parameters are doses of from 0.1 to 0.3 J/cm2, 1 to 3 J/cm2, 5 to 25 J/cm2 and 25 to 80 J/cm2, intensities are of from 1 to 10 mW/cm2, 20 to 40 mW/cm2, 100 to 400 mW/cm2, 800 to 3000 mW/cm2, continuous wave mode or pulse repetition rates of from 0 to 200 Hz and 1000 to 10000 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.
CA2437029A 1997-01-06 2000-01-28 Method and apparatus for localized low energy photon therapy (lept) Expired - Lifetime CA2437029C (en)

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US08/779,316 US6063108A (en) 1997-01-06 1997-01-06 Method and apparatus for localized low energy photon therapy (LEPT)
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