CA2448238A1 - Bone cement mixing and delivery device for injection and method thereof - Google Patents

Bone cement mixing and delivery device for injection and method thereof Download PDF

Info

Publication number
CA2448238A1
CA2448238A1 CA002448238A CA2448238A CA2448238A1 CA 2448238 A1 CA2448238 A1 CA 2448238A1 CA 002448238 A CA002448238 A CA 002448238A CA 2448238 A CA2448238 A CA 2448238A CA 2448238 A1 CA2448238 A1 CA 2448238A1
Authority
CA
Canada
Prior art keywords
set forth
piston
assembly
plunger
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002448238A
Other languages
French (fr)
Other versions
CA2448238C (en
Inventor
Jared P. Coffeen
Richard F. Huyser
Christopher M. Tague
Weston Pernsteiner
Dennis A. Stratton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stryker Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA2690894A priority Critical patent/CA2690894C/en
Publication of CA2448238A1 publication Critical patent/CA2448238A1/en
Application granted granted Critical
Publication of CA2448238C publication Critical patent/CA2448238C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8822—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8827—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it with filtering, degassing, venting or pressure relief means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
    • A61B2017/8838—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means for mixing bone cement or fluid fillers

Abstract

A bone cement mixing and delivery assembly (30) is disclosed for mixing a powdered copolymer and a liquid monomer to form a bone cement and delivering the bone cement. The assembly includes a cartridge having a distal end (34) and a proximal end (36) and defining a mixing chamber (40) between the dista l end and the proximal end. A transfer mechanism having a cap (52) and a stem supporting a piston (64) and a plunger is connected to the distal end. The transfer mechanism includes a first advancement mechanism (68) for advancing the piston and plunger in unison and a second advancement mechanism (70) for moving the plunger independent of the piston. The assembly further includes a removable handle (120) having a shaft for attachment of a mixing blade and a quick-release connector (142) and a release button (144) for locking and unlocking the mixing blade (128) from the removable handle.

Claims (48)

1. A bone cement mixing and delivery assembly for delivering a bone cement, paid assembly comprising:
a cartridge having a distal end and a proximal end and defining a chamber Between said distal end and said proximal end;
a lid connected to said proximal end and having an aperture;
a piston disposed in said chamber for transferring said bone cement from paid chamber to said proximal end;
a transfer mechanism adjacent to said distal end and in sealing engagement with said cartridge, said transfer mechanism moving said piston through said chamber;
and a plunger extendable from said piston for forcing said bone cement through said aperture.
2. An assembly as set forth in claim 1 wherein said transfer mechanism includes a first advancement mechanism for advancing said piston and said plunger in unison.
3. An assembly as set forth in claim 2 wherein said transfer mechanism includes a second advancement mechanism for advancing said plunger relative to said piston.
4. An assembly as set forth in claim 3 further including an delivery cartridge having a cartridge end connected to said aperture and extending to an open end with a smaller diameter than said chamber, said plunger having a cross section permitting the plunger to extend through said aperture and into said delivery cartridge.
5. A bone cement mixing and delivery assembly for mixing a powdered copolymer and a liquid monomer to form a bone cement and delivering the bone cement, said assembly comprising:

a cartridge having a distal end and a proximal end and defining a chamber between said distal end and said proximal end;
a lid connected to said proximal end and having an aperture;
a piston disposed in said chamber and presenting a face for transferring the bone cement from said chamber to said proximal end;
a plunger moveable relative to said piston for extending from said piston and into said aperture for forcing the bone cement through said aperture; and a transfer mechanism connected to said distal end of said cartridge for moving said piston and said plunger in unison to a stop position that limits further movement of said piston and thereafter moves said plunger relative to said piston and into said aperture.
6. An assembly as set forth in claim 5 wherein said transfer mechanism includes a cap surrounding said distal end and a first advancement mechanism interconnected between said cap and said distal end for moving said piston and said plunger in unison and a second advancement mechanism for moving said plunger relative to said piston.
7. An assembly as set forth in claim 6 wherein said first advancement mechanism includes male threads on said distal end and female threads inside said cap threadably engaging said male threads for moving said cap axially over said cartridge upon rotation of said cap relative to said cartridge.
8. An assembly as set forth in claim 6 wherein said second advancement mechanism includes coacting threads interconnecting said plunger and said piston for moving said plunger axially relative to said piston in response to rotation of said cap at said stop position.
9. An assembly as set forth in claim 7 wherein said second advancement mechanism includes a rack on said plunger and a gear engaging said rack to move said plunger relative to said piston upon rotation of said gear.
10. An assembly as set forth in claim 7 wherein said cap includes a stem and said piston is rotatably supported on said stem, a pin system interconnecting said piston and said stem for preventing relative rotation between said piston and said stem until said piston moves to said stop position, said first advancement mechanism includes a disconnect system for disconnecting said female threads from said male threads for allowing rotation of said cap relative to said cartridge without relative axial movement therebetween at said stop position.
11. An assembly as set forth in claim 10 wherein said disconnect system includes an annular recess in said cartridge adjacent said male threads and a plurality of circumferential segments forming said female threads and a first biasing device for moving said segments radially into said annular recess at said stop position.
12. An assembly as set forth in claim 10 wherein said first advancement mechanism includes a tongue and a groove interconnecting said plunger and said stem for rotating said plunger with said stem while allowing said plunger to move axially relative to said stem.
13. An assembly as set forth in claim 10 wherein said pin is disposed radially to interconnect said stem and said piston, a second biasing device for urging said pin out radially and into engagement with said cartridge, said cartridge having a channel adjacent said proximal end for receiving said pin at said stop position to prevent rotation of said piston and thereby to cause axial movement of said plunger relative to said piston in response to rotation of said cap at said stop position.
14. An assembly as set forth in claim 5 further comprising at least one indicator indicating an amount of the bone cement to be delivered upon rotation of said second advancement mechanism.
15. An assembly as set forth in claim 5 further comprising a vent connected to said lid for removing gas particles from said chamber.
16. An assembly as set forth in claim 15 further comprising a filter disposed within said vent for filtering said gas particles.
17. An assembly as set forth in claim 5 further comprising a cooling chamber positioned adjacent said chamber for receiving a cooling fluid to cool said chamber.
18. An assembly as set forth in claim 5 further comprising a removable handle extending through said aperture and having a first end and a second end.
19. An assembly as set forth in claim 18 wherein said removable handle is coextensive with said plunger whereby actuation of said transfer mechanism extends said plunger from said piston.
20. An assembly as set forth in claim 19 further comprising a pivot interconnecting said plunger and said removable handle for allowing said removable handle to extend at a right angle from said plunger.
21. An assembly as set forth in claim 20 further comprising a cap stop extending from said transfer mechanism and positioned for engagement with said removable handle when said removable handle is positioned at a right angle to said plunger whereby said removable handle aids in rotation of said transfer mechanism.
22. An assembly as set forth in claim 18 further comprising a mixing blade releasably attached to said removable handle.
23. An assembly as set forth in claim 22 further comprising a quick-release connector between said mixing blade and said removable handle.
24. A method of delivering a bone cement from a cartridge having a distal end and a proximal end defining a chamber therebetween and an aperture in the proximal end, said method comprising the steps of:
filing a chamber having a proximal end with the bone cement;

advancing a piston and a plunger in unison within the chamber for transferring the bone cement out of an aperture in the proximal end of the chamber; and advancing the plunger independently of the piston to extend the plunger beyond the piston and into the aperture.
25. A method as set forth in claim 24 wherein the bone cement further includes a liquid monomer and a powdered copolymer and further including the step of disposing the liquid monomer and the powdered copolymer into the chamber.
26. A method as set forth in claim 25 further including the step of agitating the liquid monomer and the powdered copolymer to form the bone cement.
27. A method set forth in claim 24 further including the step of venting the chamber and removing gas particles from the chamber.
28. A method set forth in claim 27 further including the step of filtering the gas particles as the gas particles are removed from the chamber.
29. A bone cement mixing and delivery assembly for mixing a powdered copolymer with a liquid monomer to form a bone cement and delivering the bone cement, said device comprising:
a cartridge having a distal end and a proximal end .and defining a mixing chamber between said distal end and said proximal end;
a lid connected to said proximal end and having an aperture;
a removable handle extending through said aperture and having a first end and a second end defining a hollow cavity between said first end and said second end;
a shaft disposed within said hollow cavity and extending from said first end of said removable handle;
a mixing blade having a bore and said bore receiving said first end of said removable handle; and a quick-release connector between said mixing blade and said shaft such that said mixing blade is releasable from said removable handle.
30. An assembly as set forth in claim 29 wherein said quick-release connector further comprises a release button engaging said shaft and being moveable between a locked and an unlocked position for locking and unlocking said mixing blade to said removable handle.
31. An assembly as set forth in claim 30 wherein said quick-release connector further comprises a flange extending from. said bore of said mixing blade and a flange recess disposed in said first end of said removable handle such that in said unlocked position said flange engages said flange recess.
32. An assembly as set forth in claim 31 wherein said shaft further comprises a blade attachment end extending through said bore, said blade attachment end having a projection for engaging said flange wherein engagement of said flange occurs when said release button is in said locked position and said flange is in said flange recess.
33. An assembly as set forth in claim 32 further including a piston disposed in said mixing chamber and presenting a face for transferring the bone cement from said mixing chamber to said proximal end.
34. An assembly as set forth in claim 33 further including a plunger moveable relative to said piston for extending from said piston and into said aperture for forcing the bone cement through said aperture.
35. An assembly as set forth in claim 34 further including a transfer mechanism connected to said distal end of said cartridge for moving said piston and said plunger in unison to a stop position that limits further movement of said piston and thereafter moves said plunger relative to said piston and into said aperture.
36. An assembly as set forth in claim 35 wherein said transfer mechanism includes a cap surrounding said distal end and a first advancement mechanism interconnected between said cap and said distal end for moving said piston and said plunger in unison and a second advancement mechanism for moving said plunger relative to said piston.
37. An assembly as set forth in claim 36 wherein said first advancement mechanism includes male threads on said distal end and female threads inside said cap threadably engaging said male threads for moving said cap axially over said cartridge upon rotation of said cap relative to said cartridge.
38. An assembly as set forth in claim 37 wherein said second advancement mechanism includes coacting threads interconnecting said plunger and said.
piston for moving said plunger axially relative to said piston in response to rotation of said cap at said stop position.
39. An assembly as set forth in claim 29 further comprising a vent connected to said lid for removing gas particles from said mixing chamber.
40. An assembly as set forth in claim 39 further comprising a filter disposed within said vent for filtering said gas particles.
41. An assembly as set forth in claim 29 further comprising a cooling chamber positioned adjacent said mixing chamber for receiving a cooling fluid to cool said mixing chamber.
42. An assembly as set forth in claim 30 wherein said quick-release connector further comprises a collapsible ball extending from said first end of said removable handle and engaging said mixing blade such that in said unlocked position said collapsible ball collapses thereby releasing said mixing blade.
43. A method of mixing a powdered copolymer and a liquid monomer to form a bone cement in a cartridge having a distal end and a proximal and defining a mixing chamber therebetween with a removable handle having a release button and a quick-release connector for attachment to a mixing blade and a lid having an aperture connected to the proximal end, said method comprising the steps of:
disposing the powdered copolymer and the liquid monomer into the mixing chamber;

connecting the lid to the proximal end to seal the mixing chamber having the mixing blade disposed within the mixing chamber;
agitating the powdered copolymer and the liquid monomer with the mixing blade by manipulating the removable handle to form the bone cement; and actuating the release button and releasing the mixing blade from the quick-release connector such that the removable handle is removable through the aperture and the mixing blade remains in the mixing chamber.
44. A method as set forth in claim 43 wherein the quick-release connector further includes a shaft disposed within the removable handle and connected to the release button and wherein the step of actuating the release button further comprises the step of sliding the release button and rotating the shaft to unlock the mixing blade from the removable handle.
45. A method as set forth in claim 43 wherein the step of connecting the lid further comprises the step of inserting the removable handle through the aperture of the lid prior to connecting the lid to the proximal end.
46. A method as set forth in claim 45 wherein the step of connecting the lid further comprises the step of attaching the mixing blade to the shaft while the release button is in the unlocked position and sliding the release button to a locked position for locking the mixing blade to the removable handle such that mixing blade is on one side of the lid, and it enters the mixing chamber as the lid is connected.
47. A method as set forth in claim 43 further comprising the step of removing gas particles from the mixing chamber.
48. A method as set forth in claim 47 further comprising the step of filtering the gas particles as the gas particles are being removed from the mixing chamber.
CA2448238A 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof Expired - Lifetime CA2448238C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2690894A CA2690894C (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32578301P 2001-07-16 2001-07-16
US60/325,783 2001-07-16
US09/981,552 US6547432B2 (en) 2001-07-16 2001-10-17 Bone cement mixing and delivery device for injection and method thereof
US09/981,552 2001-10-17
PCT/US2002/002950 WO2003008080A1 (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2690894A Division CA2690894C (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof

Publications (2)

Publication Number Publication Date
CA2448238A1 true CA2448238A1 (en) 2003-01-30
CA2448238C CA2448238C (en) 2010-03-23

Family

ID=26985105

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2448238A Expired - Lifetime CA2448238C (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof
CA2690894A Expired - Lifetime CA2690894C (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2690894A Expired - Lifetime CA2690894C (en) 2001-07-16 2002-01-31 Bone cement mixing and delivery device for injection and method thereof

Country Status (6)

Country Link
US (5) US6547432B2 (en)
EP (2) EP2243545B1 (en)
JP (2) JP4068057B2 (en)
CA (2) CA2448238C (en)
DE (1) DE02787175T1 (en)
WO (1) WO2003008080A1 (en)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US20050228397A1 (en) * 1998-08-14 2005-10-13 Malandain Hugues F Cavity filling device
SE520688C2 (en) * 2000-04-11 2003-08-12 Bone Support Ab An injectable bone mineral replacement material
WO2002000143A1 (en) * 2000-06-27 2002-01-03 Kyphon Inc. Systems and methods for injecting flowable materials into bones
SE517168C2 (en) * 2000-07-17 2002-04-23 Bone Support Ab A composition for an injectable bone mineral replacement material
EP1458314A4 (en) 2001-02-12 2009-08-05 Allegiance Corp Multi-use surgical cement dispenser apparatus and kit for same
US6547432B2 (en) * 2001-07-16 2003-04-15 Stryker Instruments Bone cement mixing and delivery device for injection and method thereof
US7029163B2 (en) * 2002-10-07 2006-04-18 Advanced Biomaterial Systems, Inc. Apparatus for mixing and dispensing components
SE522098C2 (en) * 2001-12-20 2004-01-13 Bone Support Ab Artificial bone mineral substitute material useful as an X-ray contrast medium comprises ceramic and water soluble non-ionic X-ray contrast agent
SE524714C2 (en) * 2002-06-28 2004-09-21 Asept Medical Ab Bone cement processor and applicator
SE0300620D0 (en) * 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
EP1614403B2 (en) 2003-03-14 2014-06-18 Depuy Spine, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US20040267272A1 (en) 2003-05-12 2004-12-30 Henniges Bruce D Bone cement mixing and delivery system
US20050128867A1 (en) * 2003-05-12 2005-06-16 Henniges Bruce D. Bone cement mixing and delivery system
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
WO2006011152A2 (en) 2004-06-17 2006-02-02 Disc-O-Tech Medical Technologies, Ltd. Methods for treating bone and other tissue
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
US7909833B2 (en) * 2003-09-29 2011-03-22 Depuy Acromed, Inc. Vertebroplasty device having a flexible plunger
CA2481663A1 (en) * 2003-10-01 2005-04-01 Biomet Deutschland Gmbh Device for the mixing and discharge of liquid and pulverulent materials for medical use
SE0302983D0 (en) * 2003-11-11 2003-11-11 Bone Support Ab Apparatus for providing spongy bone with bone replacement and / or bone strengthening material and associated method
US20050105384A1 (en) * 2003-11-18 2005-05-19 Scimed Life Systems, Inc. Apparatus for mixing and dispensing a multi-component bone cement
US7524103B2 (en) * 2003-11-18 2009-04-28 Boston Scientific Scimed, Inc. Apparatus for mixing and dispensing a multi-component bone cement
EP1708654B1 (en) * 2003-12-01 2007-05-09 Broockeville Corporation N.V. A two-component mixing and dispensing device
US20050222538A1 (en) * 2004-03-30 2005-10-06 Sdgi Holdings, Inc. Surgical system for delivery of viscous fluids
US20060095138A1 (en) * 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
US7988816B2 (en) 2004-06-21 2011-08-02 Tokyo Electron Limited Plasma processing apparatus and method
SE527528C2 (en) * 2004-06-22 2006-04-04 Bone Support Ab Apparatus for the preparation of curable pulp and use of the apparatus
US7618820B2 (en) * 2004-06-30 2009-11-17 Depuy Products, Inc. System and method for determining the operating state of orthopaedic admixtures
US8038682B2 (en) * 2004-08-17 2011-10-18 Boston Scientific Scimed, Inc. Apparatus and methods for delivering compounds into vertebrae for vertebroplasty
US20080319445A9 (en) * 2004-08-17 2008-12-25 Scimed Life Systems, Inc. Apparatus and methods for delivering compounds into vertebrae for vertebroplasty
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7678116B2 (en) * 2004-12-06 2010-03-16 Dfine, Inc. Bone treatment systems and methods
US7559932B2 (en) * 2004-12-06 2009-07-14 Dfine, Inc. Bone treatment systems and methods
US8070753B2 (en) * 2004-12-06 2011-12-06 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
US20060122614A1 (en) * 2004-12-06 2006-06-08 Csaba Truckai Bone treatment systems and methods
US7717918B2 (en) * 2004-12-06 2010-05-18 Dfine, Inc. Bone treatment systems and methods
US8029183B2 (en) * 2005-02-23 2011-10-04 Biomet Manufacturing Corp. Apparatus for mixing bone cement
KR101112552B1 (en) * 2005-03-08 2012-02-15 삼성전자주식회사 Lens for light emitting diode, light emitting lens, back light assembly and liquid crystal display
EP1874238A2 (en) * 2005-04-29 2008-01-09 Wyeth Drug delivery devices and related components, systems and methods
US20070005075A1 (en) * 2005-06-17 2007-01-04 Bogert Roy B Telescoping plunger assembly
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) * 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US9066769B2 (en) 2005-08-22 2015-06-30 Dfine, Inc. Bone treatment systems and methods
US8777479B2 (en) * 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
US8540723B2 (en) * 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
US8562620B2 (en) 2008-04-21 2013-10-22 Dfine, Inc. Bone treatment systems
US20070162043A1 (en) * 2005-09-01 2007-07-12 Csaba Truckai Methods for sensing retrograde flows of bone fill material
KR101299309B1 (en) * 2005-09-07 2013-08-26 토마스 스테펜 Device for injecting high viscosity material
DE102005045227A1 (en) * 2005-09-22 2007-03-29 Amedo Gmbh Bone cement application system
CN101365503B (en) 2005-11-09 2012-02-29 海浦德科公司 Syringe devices, components of syringe devices, and methods of forming components and syringe devices
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
US8574237B2 (en) * 2005-12-30 2013-11-05 DePuy Synthes Products, LLC Method and apparatus for predicting the operating points of bone cement
DE602007008528D1 (en) * 2006-02-10 2010-09-30 Barger Mark A Apparatus and method comprising a retractable mixing element
US7922690B2 (en) * 2006-02-22 2011-04-12 Michael Plishka Curable material delivery device
US8361032B2 (en) * 2006-02-22 2013-01-29 Carefusion 2200 Inc. Curable material delivery device with a rotatable supply section
US20080015539A1 (en) * 2006-02-28 2008-01-17 Robert Pieroni Bottle with adapter for receiving needleless syringe
US8394105B2 (en) * 2006-03-14 2013-03-12 DePuy Synthes Products, LLC Apparatus for dispensing bone cement
US20080027456A1 (en) * 2006-07-19 2008-01-31 Csaba Truckai Bone treatment systems and methods
MX2009002455A (en) * 2006-09-07 2009-03-20 Wyeth Corp Bone cement mixing systems and related methods.
CN101516412B (en) 2006-09-14 2014-02-12 德普伊斯派尔公司 Bone cement and use method thereof
ITRM20060513A1 (en) * 2006-09-29 2008-03-30 2B1 S R L INJECTION DEVICE OF BONE CEMENT IN PARTICULAR FOR VERTEBROPLASTIC
AU2007311451A1 (en) 2006-10-19 2008-04-24 Depuy Spine, Inc. Fluid delivery system
US8696679B2 (en) * 2006-12-08 2014-04-15 Dfine, Inc. Bone treatment systems and methods
WO2008097855A2 (en) * 2007-02-05 2008-08-14 Dfine, Inc. Bone treatment systems and methods
US8556910B2 (en) 2007-04-03 2013-10-15 Dfine, Inc. Bone treatment systems and methods
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
US9597118B2 (en) 2007-07-20 2017-03-21 Dfine, Inc. Bone anchor apparatus and method
US9522097B2 (en) 2007-10-04 2016-12-20 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US8002737B2 (en) 2007-10-04 2011-08-23 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US20090099660A1 (en) * 2007-10-10 2009-04-16 Warsaw Orthopedic, Inc. Instrumentation to Facilitate Access into the Intervertebral Disc Space and Introduction of Materials Therein
US9445854B2 (en) * 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
US9161798B2 (en) 2008-02-01 2015-10-20 Dfine, Inc. Bone treatment systems and methods
US20100030220A1 (en) * 2008-07-31 2010-02-04 Dfine, Inc. Bone treatment systems and methods
EP2252336B1 (en) * 2008-02-28 2014-06-25 Dfine, Inc. Bone treatment systems and methods
US8840592B2 (en) 2008-03-12 2014-09-23 Warsaw Orthopedic, Inc. Piston for material delivery system
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
US8317800B2 (en) * 2008-04-22 2012-11-27 Warsaw Orthopedic, Inc. Injectable material delivery device with an integrated mixer
US20090308895A1 (en) * 2008-06-13 2009-12-17 Reynolds David L Rack and pinon drive for by-pass cartridge
AU2009270307B2 (en) * 2008-07-15 2013-03-21 Lorne Beckman Bone cement injection device
US8308731B2 (en) * 2008-09-02 2012-11-13 Cook Medical Technologies Llc Vertebroplasty all in one mixer
AU2009296318B2 (en) * 2008-09-29 2014-09-18 Lidds Ab Injector device
US20100114067A1 (en) * 2008-10-31 2010-05-06 Warsaw Orthopedic, Inc. Multi-Chamber Mixing System
US20100213085A1 (en) * 2009-02-25 2010-08-26 Nicole Belnap Apparatus, system, and method for selectively mixing two substances
DE102009013211B4 (en) 2009-03-17 2012-04-19 Aap Biomaterials Gmbh Bone cement vacuum mixing device and method for mixing bone cement
CN102395393A (en) * 2009-04-03 2012-03-28 Ebi有限责任公司 Method and apparatus for delivering bone cement
WO2011054110A1 (en) * 2009-11-06 2011-05-12 Socpra Sciences Et Genie S. E. C. Bone cement delivery system
WO2011083357A1 (en) * 2010-01-08 2011-07-14 Vexim Sas Devices, methods and systems for mixing and dispensing flowable material
PT2528548E (en) * 2010-01-25 2015-02-04 Tecres Spa Device to prepare and administer a two-component mixture
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
DE102010019220B4 (en) * 2010-05-04 2015-03-26 Heraeus Medical Gmbh Cartridge system with connected delivery pistons
US8408250B2 (en) 2010-06-18 2013-04-02 Warsaw Orthopedic, Inc. Bone replacement material mixing and delivery devices and methods of use
US20120064481A1 (en) * 2010-09-13 2012-03-15 Wade Cannon Composite delivery system
DE102010046054B4 (en) 2010-09-22 2012-05-31 Heraeus Medical Gmbh Synchronized discharge device
JP2014030436A (en) * 2010-11-19 2014-02-20 Terumo Corp Medicine injection tool
DE102011101486A1 (en) 2011-05-13 2012-11-15 Heraeus Medical Gmbh Device and method for degassing and discharging bone cement
ES2675125T3 (en) 2011-07-20 2018-07-06 Stryker Corporation Manifold to fill a plurality of cannulas
DE102011112516B4 (en) 2011-09-07 2024-02-29 Stryker European Operations Holdings Llc Container with a container for holding a liquid and a liquid removal device
US9630355B2 (en) 2011-11-30 2017-04-25 King Abdulaziz City For Science And Technology Batch mixer with plunger
CN103251443A (en) * 2012-02-16 2013-08-21 上海康德莱企业发展集团医疗器械有限公司 Bone cement pushing and injecting pump
DE102012024710A1 (en) * 2012-11-07 2014-05-08 Heraeus Medical Gmbh Device for mixing and discharging a pasty mass
PL2958603T3 (en) 2013-02-20 2018-10-31 Bone Support Ab Improved setting of hardenable bone substitute
GB2514535A (en) * 2013-03-18 2014-12-03 Summit Medical Ltd An apparatus for mixing and delivering bone cement
US10092342B2 (en) 2013-04-30 2018-10-09 Stryker Corporation Bone cement delivery assembly with leakage prevention valve
AU2013388139B2 (en) 2013-04-30 2019-02-14 Stryker Corporation Bone cement delivery assembly with leakage prevention valve
US10478852B2 (en) * 2014-02-26 2019-11-19 3M Innovative Properties Company Device for dispensing a material
KR101544922B1 (en) * 2014-06-23 2015-08-18 (주)인젝타 Cartridge for mixing and injecting bone cement and bone cement mixing and injecting system comprising the same
US9582482B1 (en) 2014-07-11 2017-02-28 Google Inc. Providing an annotation linking related entities in onscreen content
CN105055012B (en) * 2015-08-13 2018-09-14 广州爱锘德医疗器械有限公司 Bone cement stirring syringe
US9931468B1 (en) 2015-11-02 2018-04-03 Abyrx Inc. Combined mixing and dispensing device for surgical material
US9808775B2 (en) 2016-01-29 2017-11-07 Kyphon SÀRL Manual mixer
CA3032123A1 (en) 2016-07-29 2018-02-01 Alcyone Lifesciences, Inc. Automated drug delivery systems and methods
MX2019005153A (en) 2016-11-02 2019-11-12 J P Velis Christopher Devices and methods for slurry generation.
US11324673B2 (en) 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
CN106580420B (en) * 2016-11-23 2023-04-11 安徽奥弗智能微创医疗器械集团有限公司 Automatic propeller for bone cement
KR102562024B1 (en) * 2016-12-02 2023-08-02 데비코어 메디컬 프로덕츠, 인코포레이티드 Apparatus to allow biopsy sample visualization during tissue removal
CN106618715A (en) * 2016-12-22 2017-05-10 上海凯利泰医疗科技股份有限公司 Bone cement push-injection device
WO2018156755A1 (en) 2017-02-22 2018-08-30 Stryker Corporation Flow diverter for bone cement delivery systems
KR102589816B1 (en) 2017-04-05 2023-10-16 미라키 이노베이션 씽크 탱크 엘엘씨 Low-temperature slurry containment
EP3606482A4 (en) 2017-04-05 2021-01-06 Miraki Innovation Think Tank LLC Point of delivery cold slurry generation
EP3661660A4 (en) * 2017-08-04 2021-05-19 Mark Robert Towler A storage, mixing and dispensing device
US10500342B2 (en) 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
CA3101054A1 (en) 2018-04-11 2019-10-17 Stryker Corporation Curable material dispensing system and methods of operating and packaging the same
CN108498830B (en) * 2018-05-28 2021-03-26 刘明 Medical degassing unit for dispensing robot
DE102018209784A1 (en) * 2018-06-18 2019-12-19 Heraeus Medical Gmbh Bone cement applicator with retractable mixing stick and method for producing a bone cement
DE102018209807A1 (en) * 2018-06-18 2019-12-19 Heraeus Medical Gmbh Bone cement applicator with retractable mixing stick and method for producing a bone cement
CN108970509B (en) * 2018-08-23 2021-06-11 谭从喜 Papermaking sludge is environmental protection equipment for recovery processing
EP3643398B1 (en) * 2018-10-25 2021-07-07 Heraeus Medical GmbH Device and method for producing bone cement
DE102018131268B4 (en) 2018-12-07 2021-11-25 Heraeus Medical Gmbh Device for mixing a bone cement with a cavity for monomer transfer
DE102019104020A1 (en) * 2019-02-18 2020-08-20 Heraeus Medical Gmbh Bone cement applicator with clampable discharge piston
WO2020219392A2 (en) 2019-04-24 2020-10-29 Stryker Corporation Systems and methods for off-axis augmentation of a vertebral body
US11191575B2 (en) 2019-06-07 2021-12-07 Stryker Corporation Systems and methods for off-axis augmentation of a vertebral body
AU2020294027A1 (en) 2019-06-14 2021-12-23 Stryker Corporation Mixing device and methods for making bone cement
EP3811881B1 (en) * 2019-10-22 2024-01-10 Heraeus Medical GmbH Device for applying bone cement
CN111111521B (en) * 2019-12-03 2021-11-19 上海伦英生物科技有限公司 Mask machine, method for manufacturing mask by using mask machine and manufactured mask
WO2022066743A2 (en) 2020-09-22 2022-03-31 Stryker Corporation Systems and methods for augmentation of a vertebral body
CN114209477B (en) * 2021-12-20 2022-08-26 浙江大学 Novel bone grafting device
CN114713165B (en) * 2022-02-12 2023-08-29 宁波乐维实业有限公司 Production device for preparing ethanolamine
WO2023239769A1 (en) 2022-06-07 2023-12-14 Stryker Corporation Bone cement system and related assemblies and methods

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1612996A (en) * 1926-02-23 1927-01-04 Waagbo Herman Cream-testing device
US1694845A (en) * 1927-03-16 1928-12-11 Trey Emanuel De Kneading device
US1998692A (en) * 1933-10-10 1935-04-23 Oramold Products Corp Kneading or mixing device
US3144966A (en) * 1962-04-16 1964-08-18 Semco Res Inc Cartridge for mixing and dispensing sealant compound
US3217946A (en) * 1962-04-20 1965-11-16 Semco Sales & Service Inc Mixing cartridge for sealant compound
US3216616A (en) * 1964-03-02 1965-11-09 Jr Homer Blankenship Syringe with upper and lower bores
US3477431A (en) * 1967-02-03 1969-11-11 Abbott Lab Combined mixing syringe and container
US3459341A (en) * 1967-11-07 1969-08-05 Jacob C Copeland Piston type dispenser
US3815790A (en) * 1972-09-18 1974-06-11 Kensington Scient Corp Precision liquid pipetting devices
US4010934A (en) * 1976-03-17 1977-03-08 Mccord King S Liquid mixing and dispensing device
US4116240A (en) * 1977-03-11 1978-09-26 Guiney Aeneas C Mixing syringe
US4114927A (en) * 1977-07-07 1978-09-19 Butcher Norman P Tube coupling for vacuum cleaners
FR2400122A1 (en) * 1977-08-11 1979-03-09 Wedekind Denso Chemie CYLINDER AND PISTON DEVICE INTENDED IN PARTICULAR FOR CARTRIDGES FOR SPRAYING OR PROJECTING CEMENT, SEALANTS, SEALING SUBSTANCES, LACQUERS, ETC.
CA1113894A (en) * 1978-01-07 1981-12-08 Hans W. Korte-Jungermann Injection cartridge
US4338925A (en) 1979-12-20 1982-07-13 Jo Miller Pressure injection of bone cement apparatus and method
US4405249A (en) 1980-03-28 1983-09-20 National Research Development Corporation Dispensing apparatus and method
US4371094A (en) * 1980-07-31 1983-02-01 Products Research & Chemical Corporation Barrier two part pairing and dispensing cartridge
US4461407A (en) 1981-04-10 1984-07-24 Danny Finnegan Automatic pressure release mechanism for caulk gun
NZ200043A (en) * 1981-04-15 1986-01-24 W Maurer Producing soft ice-cream by fragmenting frozen block under gas-pressure
ZA837485B (en) * 1982-11-05 1984-06-27 Dentsply Int Inc Syringes
US4693656A (en) 1983-09-01 1987-09-15 5W Enterprises, Inc. Quick adjusting nut
US4546767A (en) 1983-10-27 1985-10-15 Smith Carl W Cement injection device
DE8335529U1 (en) * 1983-12-10 1984-03-08 Upat Gmbh & Co, 7830 Emmendingen SPRAY CARTRIDGE
DE8420774U1 (en) 1984-07-11 1985-09-12 Draenert, Klaus, Dr.Med. Dr.Med.Habil., 8000 Muenchen Device for mixing and applying bone cement
US4653487A (en) 1986-01-29 1987-03-31 Maale Gerhard E Intramedullary rod assembly for cement injection system
DE3609672A1 (en) 1986-03-21 1987-09-24 Klaus Draenert EVACUABLE BONE CEMENT SYRINGE
JPH0820342B2 (en) * 1989-03-30 1996-03-04 日立金属株式会社 Thermal stress prediction method for heat resistant materials
US5071040A (en) 1990-03-09 1991-12-10 Pfizer Hospital Products Group, Inc. Surgical adhesives mixing and dispensing implement
US4994065A (en) 1990-05-18 1991-02-19 Zimmer, Inc. Apparatus for dispensing low viscosity semi-fluid material under pressure
US5181636A (en) 1990-12-14 1993-01-26 Milbar Corporation Incremental dispensing device
US5431654A (en) 1991-09-30 1995-07-11 Stryker Corporation Bone cement injector
AU7324394A (en) 1993-07-06 1995-02-06 Michael L. Earle Bone cement delivery gun
US5341964A (en) 1993-08-12 1994-08-30 Milbar Corporation Cartridge bias assembly for dispensing device
US5541964A (en) * 1993-08-30 1996-07-30 At&T Corp. Distortion compensation technique
DE4338553A1 (en) * 1993-11-08 1995-05-18 Ferring Arzneimittel Gmbh Injection syringe for mixing and applying injection substances
US5501374A (en) 1994-06-17 1996-03-26 Vital Products, Co. Device for extruding high viscosity fluid having multiple modes of operation
DE4425218A1 (en) 1994-07-16 1996-01-18 Merck Patent Gmbh Device for mixing and discharging bone cement
US5556009A (en) 1994-07-18 1996-09-17 Wagner Spray Tech Corporation Adjustable constant pressure caulk gun
US5697932A (en) 1994-11-09 1997-12-16 Osteonics Corp. Bone graft delivery system and method
US5638997A (en) 1995-09-18 1997-06-17 Zimmer, Inc. Bone cement injector gun
US5893488A (en) 1995-09-18 1999-04-13 Bristol-Myers Squibb Co. Bone cement injector gun
US5624184A (en) * 1995-10-10 1997-04-29 Chan; Kwan-Ho Bone cement preparation kit having a breakable mixing shaft forming an output port
US5762237A (en) 1996-02-06 1998-06-09 Chang; Peter J. Cartridge lock for caulk dispensing devices
US5729865A (en) * 1996-03-07 1998-03-24 Bestt Rollr, Inc. Lock for telescoping extension poles
US5681317A (en) 1996-06-12 1997-10-28 Johnson & Johnson Professional, Inc. Cement delivery system and method
US5879116A (en) 1996-09-23 1999-03-09 Criswell; Richard Self-locking machine screw for high temperature applications
US5876116A (en) * 1996-11-15 1999-03-02 Barker; Donald Integrated bone cement mixing and dispensing system
US6033105A (en) * 1996-11-15 2000-03-07 Barker; Donald Integrated bone cement mixing and dispensing system
CN1244815A (en) 1996-12-13 2000-02-16 诺瑞安有限公司 Preparation, storage and administration of cements
US6086694A (en) * 1997-04-01 2000-07-11 Stanley Lerner High speed web machine
US5829875A (en) * 1997-04-02 1998-11-03 Simpson Strong-Tie Co., Inc. Combined barrier and mixer assembly for a cylindrical container
US6048346A (en) 1997-08-13 2000-04-11 Kyphon Inc. Systems and methods for injecting flowable materials into bones
US5950344A (en) * 1997-10-30 1999-09-14 Ross; Larry Quick-release gun lock
US6019765A (en) 1998-05-06 2000-02-01 Johnson & Johnson Professional, Inc. Morsellized bone allograft applicator device
EP1077654B1 (en) * 1998-05-15 2004-03-24 Shlomo Gabbay Intra vascular implant and method of manufacture thereof
US6086594A (en) 1998-10-16 2000-07-11 Brown; Byron L. Cement pressurizing device
US6155463A (en) 1998-10-27 2000-12-05 Z-Pro International, Inc. Viscous material dispenser
US6120174A (en) * 1999-01-14 2000-09-19 Bristol-Myers Squibb Apparatus and method for mixing and dispensing bone cement
JP2001132559A (en) * 1999-11-04 2001-05-15 Aisan Ind Co Ltd Evaporation fuel processing device for internal combustion engine
JP2001196294A (en) * 2000-01-14 2001-07-19 Mitsubishi Electric Corp Method of exposure-processing semiconductor device
US6547432B2 (en) * 2001-07-16 2003-04-15 Stryker Instruments Bone cement mixing and delivery device for injection and method thereof
US7029163B2 (en) * 2002-10-07 2006-04-18 Advanced Biomaterial Systems, Inc. Apparatus for mixing and dispensing components
US6984063B2 (en) * 2002-10-07 2006-01-10 Advanced Biomaterial Systems, Inc. Apparatus for mixing and dispensing components
DE10242984B4 (en) * 2002-09-17 2010-09-23 Sanatis Gmbh Device for producing mixtures of two components

Also Published As

Publication number Publication date
US20030012079A1 (en) 2003-01-16
CA2448238C (en) 2010-03-23
US6547432B2 (en) 2003-04-15
EP1406721A4 (en) 2006-07-05
EP1406721A1 (en) 2004-04-14
JP2007275888A (en) 2007-10-25
US7306361B2 (en) 2007-12-11
US7320540B2 (en) 2008-01-22
US6736537B2 (en) 2004-05-18
EP2243545B1 (en) 2012-11-28
WO2003008080A1 (en) 2003-01-30
US20070041267A1 (en) 2007-02-22
EP2243545A1 (en) 2010-10-27
JP2005500103A (en) 2005-01-06
CA2690894C (en) 2012-09-11
US20060158957A1 (en) 2006-07-20
JP4068057B2 (en) 2008-03-26
DE02787175T1 (en) 2004-09-30
JP4762950B2 (en) 2011-08-31
CA2690894A1 (en) 2003-01-30
US20040174768A1 (en) 2004-09-09
US20030012080A1 (en) 2003-01-16
US7134782B2 (en) 2006-11-14

Similar Documents

Publication Publication Date Title
CA2448238A1 (en) Bone cement mixing and delivery device for injection and method thereof
US7677418B2 (en) Bone cement cartridge with a releasably locked drive piston, the piston configured to be unlocked by a delivery device
JP3324752B2 (en) Method and apparatus for injecting fluids into animals and disposable front-loading syringes therefor
EP2802799B1 (en) Quick connect fluid connector
EP2130565B1 (en) Connector for a medical instrument
EP2656814A2 (en) A droplet jet teeth cleaning system
JP2000517205A (en) Fitting for medical cannula
EP2839872B1 (en) Delivery gun for dispensing bone cement from a cartridge, the gun having a multi-link linkage capable of dispensing the cement at different flow rates
US6238211B1 (en) Fitting for dental syringe
KR102322193B1 (en) Dispensing devices for use with side-by-side fluid cartridges and related methods
EP2931171B1 (en) Device for dispensing a dental material with locking mechanism
JP7204775B2 (en) Fittings and methods for transferring fluids
EP3559539B1 (en) Grease coupler

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20220131