CA2449903A1 - Antiperspirant or deodorant compositions comprising ppar-activating unsaturated fatty acid - Google Patents

Antiperspirant or deodorant compositions comprising ppar-activating unsaturated fatty acid Download PDF

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Publication number
CA2449903A1
CA2449903A1 CA002449903A CA2449903A CA2449903A1 CA 2449903 A1 CA2449903 A1 CA 2449903A1 CA 002449903 A CA002449903 A CA 002449903A CA 2449903 A CA2449903 A CA 2449903A CA 2449903 A1 CA2449903 A1 CA 2449903A1
Authority
CA
Canada
Prior art keywords
acid
composition according
fatty acid
composition
ppar activating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002449903A
Other languages
French (fr)
Other versions
CA2449903C (en
Inventor
Andrew Easson Mayes
Anthony Vincent Rawlings
Allan Watkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever PLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2449903A1 publication Critical patent/CA2449903A1/en
Application granted granted Critical
Publication of CA2449903C publication Critical patent/CA2449903C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/046Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/28Zirconium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/58Metal complex; Coordination compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

Antiperspirant compositions comprising an astringent aluminium or zirconium salt can suffer from perceived irritancy when applied topically, which can b e ameliorated or overcome by incorporating within the composition a peroxisome proliferator-activated receptor (PPAR) activating fatty acid and/or hydrolysable precursor thereof such as triglyceride or ester of the PPAR, especially in an amount selected in the range of from 0.5 to 10 wt. %. The compositions advantageously comprise an activated aluminium salt or aluminiu m- zirconium glycine complex.

Claims (18)

1. An antiperspirant cosmetic composition suitable for topical application to the human skin, comprising:
i. an antiperspirant active comprising an astringent aluminium or zirconium salt;
ii. a carrier for the antiperspirant active; and iii. either (a) a PPAR activating fatty acid other than at least 1% by weight of ricinoleic acid or linoleic acid or (b) a hydrolysable precursor of a PPAR
activating fatty acid other than borage oil, castor oil or sunflower seed oil in an effective amount that is insufficient to gel the composition by itself.
2. A composition according to claim 1 characterised in that the hydrolysable precursor comprises a triglyceride or ester of the PPAR activating fatty acid.
3. A composition according to any preceding claim characterised in that the PPAR activating fatty acid is olefinically unsaturated.
4. A composition according to any preceding claim characterised in that the PPAR activating fatty acid is selected from petroselinic acid, cis-9-traps-11 conjugated linoleic acid, traps-10-cis-12 conjugated linoleic acid, 7-traps octadecanoic acid, cis-parinaric acid, docosahexenoic acid, cis-4,7,10,13,16,19 , docosahexenoic acid, ricinolaidic acid, stearidonic acid, columbinic acid, linolenelaidic acid, vaccenic acid, eicosapentanoic acid, and pinolenic acid, incorporated as such or in a hydrolysable precursor thereof.
5. A composition according to claim 4 characterised in that it contains a triglyceride-containing oil selected from coriander seed oil, balsimina seed oil, parinarium laurinarium kernel fat or sabastiana brasilinensis seed oil, dehydrated castor seed oil, and aquilegia vulgaris oil.
6. A composition according to claim 4 characterised in that the PPAR activating fatty acid contains 16 or 18 carbon atoms.
7. A composition according to claim 6 characterised in that the PPAR activating fatty acid comprises petroselinic acid.
8. A composition according to claim 5 characterised in that it contains coriander seed oil.
9. A composition according to claim 1 characterised in that it comprises from 0.1 to 20% by weight and preferably 0.5 to 10% by weight of the PPAR activating fatty acid or hydrolysable precursor thereof.
10. A composition according to any preceding claim characterised by employing a combination of the PPAR

activating fatty acids or their precursors in a weight ratio of from 5:1 to 1:5.
11. A composition according to any preceding claim characterised in that it comprises from 10 to 30% by weight antiperspirant active.
12. A composition according to any preceding claim characterised in that the antiperspirant active contains aluminium chlorohydrate and/or aluminium/zirconium glycine complex.
13. A composition according to any preceding claim characterised in that it comprises a volatile silicone carrier, preferably in an amount of from 10 to 70 wt%.
14. A composition according to any preceding claim characterised in that it comprises a structurant or thickening agent in a concentration sufficient to produce a firm stick or a soft solid.
15. A composition according to any of claims 1 to 13 characterised in that comprises base composition which forms an aerosol composition together with a propellant, the weight ratio of propellant to base composition being selected within the range of from 40:60 to 99:1.
16. A method of reducing or eliminating skin irritancy arising from topical application of an antiperspirant cosmetic composition comprising an antiperspirant active comprising an astringent aluminium or zirconium salt and a carrier characterised by incorporating in the composition an effective amount of either (a) a PPAR activating fatty acid a) a PPAR activating fatty acid excluding at least 1% by weight of ricinoleic acid or linoleic acid or (b) a hydrolysable precursor of a PPAR activating fatty acid other than borage oil, castor oil or sunflower seed oil that is insufficient to gel said composition.
17. A method of reducing or eliminating sweat or body odour comprising applying topically to human skin a composition according to any preceding claim.
18. A method of reducing or eliminating skin irritancy arising from topical application of an antiperspirant cosmetic composition comprising an antiperspirant active comprising an astringent aluminium or zirconium salt and a carrier characterised by incorporating in the composition a PPAR activating fatty acid other than ~-linolenic acid or hydrolysable precursor thereof in an amount that is sufficient to reduce skin irritancy and insufficient to gel the composition.
CA2449903A 2001-06-18 2002-05-24 Antiperspirant or deodorant compositions comprising ppar-activating unsaturated fatty acid Expired - Lifetime CA2449903C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0114848.5A GB0114848D0 (en) 2001-06-18 2001-06-18 Antiperspirant or deodorant compositions
GB0114848.5 2001-06-18
PCT/EP2002/005751 WO2002102337A1 (en) 2001-06-18 2002-05-24 Antiperspirant or deodorant compositions

Publications (2)

Publication Number Publication Date
CA2449903A1 true CA2449903A1 (en) 2002-12-27
CA2449903C CA2449903C (en) 2011-09-13

Family

ID=9916831

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2449903A Expired - Lifetime CA2449903C (en) 2001-06-18 2002-05-24 Antiperspirant or deodorant compositions comprising ppar-activating unsaturated fatty acid

Country Status (14)

Country Link
US (1) US6713051B2 (en)
EP (1) EP1397116B1 (en)
AR (1) AR034490A1 (en)
AT (1) ATE367143T1 (en)
AU (1) AU2002312941B2 (en)
BR (1) BRPI0211013B1 (en)
CA (1) CA2449903C (en)
DE (1) DE60221247T2 (en)
ES (1) ES2289111T3 (en)
GB (1) GB0114848D0 (en)
MX (1) MXPA03011576A (en)
PL (1) PL205960B1 (en)
WO (1) WO2002102337A1 (en)
ZA (1) ZA200309202B (en)

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US7565383B2 (en) * 2004-12-20 2009-07-21 Sap Ag. Application recovery
US7172754B1 (en) 2005-12-23 2007-02-06 Conopco, Inc. Cosmetic emulsions with sunscreens and conjugated linoleic acid
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Also Published As

Publication number Publication date
CA2449903C (en) 2011-09-13
PL367887A1 (en) 2005-03-07
BRPI0211013B1 (en) 2017-05-09
EP1397116A1 (en) 2004-03-17
ATE367143T1 (en) 2007-08-15
AU2002312941B2 (en) 2005-05-12
MXPA03011576A (en) 2004-03-19
ZA200309202B (en) 2005-02-23
EP1397116B1 (en) 2007-07-18
ES2289111T3 (en) 2008-02-01
DE60221247T2 (en) 2007-11-22
US20030003068A1 (en) 2003-01-02
WO2002102337A1 (en) 2002-12-27
AR034490A1 (en) 2004-02-25
GB0114848D0 (en) 2001-08-08
BR0211013A (en) 2004-08-10
PL205960B1 (en) 2010-06-30
US6713051B2 (en) 2004-03-30
DE60221247D1 (en) 2007-08-30

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