CA2456502A1 - Pack containing medicament and dispensing device - Google Patents

Pack containing medicament and dispensing device Download PDF

Info

Publication number
CA2456502A1
CA2456502A1 CA002456502A CA2456502A CA2456502A1 CA 2456502 A1 CA2456502 A1 CA 2456502A1 CA 002456502 A CA002456502 A CA 002456502A CA 2456502 A CA2456502 A CA 2456502A CA 2456502 A1 CA2456502 A1 CA 2456502A1
Authority
CA
Canada
Prior art keywords
face
lidding sheet
pack according
compartment
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002456502A
Other languages
French (fr)
Other versions
CA2456502C (en
Inventor
Andrew John Ede
Douglas Ivan Jennings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2456502A1 publication Critical patent/CA2456502A1/en
Application granted granted Critical
Publication of CA2456502C publication Critical patent/CA2456502C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0061—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using pre-packed dosages having an insert inside
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Abstract

A pack containing medicament, the pack including a base having first and second opposing faces, at least one recess being formed in the first face, a foil secured to the first face so as to form with the at least one recess a sealed compartment for housing medicament and a substantially rigid member housed in the compartment extending generally from the second face to the first face such that the member can be pushed from the second face so as to rupture the foil outwardly of the compartment at the first face without compressing the medicament and a dispensing device for use with or including such a pack having an actuator for pushing the member from the second face so as to rupture the foil outwardly of the compartment at the first place.

Claims (15)

  1. A pack containing medicament, the pack having first and second opposing faces and including:
    a base having at least one recess formed at the first face;
    a lidding sheet secured to the base at the first face so as to form with the at least one recess a sealed compartment for housing medicament; and a substantially rigid member housed in the compartment extending generally from the second face to the first face such that the member can be pushed from the second face so as to rupture the lidding sheet outwardly of the compartment at the first face without compressing the medicament.
  2. 2. A pack according to claim 1, wherein the member is generally cup-shaped, an open portion of the member facing the lidding sheet and the medicament being contained in the member.
  3. A pack according to claim 1 or 2, wherein the member is generally oval in a cross-section generally parallel with the first and second faces.
  4. 4. A pack according to claim 1, 2 or 3 wherein, at the first face, walls of the base defining the at least one recess have a shape and spacing matching a peripheral wall of the member.
  5. 5. A pack according to claim 4 wherein at least part of the peripheral wall includes a chamfer on an end surface facing said first face, the chamfer forming a cutting edge for rupturing the lidding sheet at the outer periphery of the member.
  6. 6. A pack according to any preceding claim, wherein a portion of the member facing the lidding sheet is shaped so as to rupture the foil in a predetermined pattern.
  7. 7. A pack according to any preceding claim wherein the lidding sheet is arranged so as to rupture in a predetermined pattern.
  8. 8. A pack according to claim 7, wherein the lidding sheet is formed with a weakened section adjacent the compartment such that the lidding sheet ruptures at the weakened section.
  9. 9. A pack according to claim 8, wherein the weakened section is formed by at least one of varying the thickness and material properties of the lidding sheet.
  10. 10. A pack according to claim 7, 8 or 9, wherein the lidding sheet is not secured to the base at portions around the at least one recess such that the lidding sheet tends to rupture at other portions.
  11. 11. A pack according to any preceding claim wherein the base is formed from a moulded metal and plastics material laminate.
  12. 12. A pack according to any one of claims 1 to 10 wherein the base comprises a plate with a secondary lidding sheet secured over the second face, the plate defining at least one through hole, the at least one through hole forming, together with the secondary lidding sheet, said at least one recess.
  13. 13. A pack according to claim 12 wherein a surface of said member at said second face is generally co-planar with said second face.
  14. 14. A pack according to any preceding claim wherein the member includes inner surfaces defining a volume for containing the medicament, the inner surfaces curving without discontinuities between side surfaces and a base surface so as to allow an air flow within the volume to remove contained medicament.
    15. A pack according to any preceding claim wherein the medicament is in the form of dry powder.
    16. A pack according to any preceding claim including a plurality of said compartments.
    17. A dispensing device for use with a pack according to any preceding claim, the device including:
    a dispenser outlet; and an actuator for pushing said member from the second face so as to rupture the lidding sheet outwardly of the compartment at the first face and release the medicament for dispensing through the dispenser outlet.
    18. A dispensing device according to claim 17 further including:
    a support positioned adjacent the compartment proximate the first face so as to control rupturing of the lidding sheet as the actuator pushes the member.

    19. A dispensing device according to claim 18 wherein the support extends generally around the periphery of the compartment so as to support the lidding sheet where it is secured to the base at the first face.
    20. A dispensing device according to claim 19 wherein the support includes a peripheral wall which is in line with the periphery of the compartment, a portion of the peripheral wall extending to meet the lidding sheet and the remainder of the peripheral wall having a recess adjacent the lidding sheet such that said lidding sheet ruptures along said portion and not adjacent said recess.
    21. A dispensing device according to claim 19 wherein the position of the support relative to the centre of the compartment is varied around the periphery of the compartment so as to encourage the lidding sheet to rupture in a predetermined manner and form one or more outwardly extending flaps of lidding sheet hinged at one or more predetermined positions.
    22. A dispensing device according to any one of claims 17 to 21 including:
    an indexing mechanism for successively moving each of a plurality of compartments to a position adjacent the actuator for dispensing the contents of the respective compartments.
    23. A device according to any one of claims 17 to 22 when appendant on
  15. claim 15 for use as a dry powder dispenser for lungs or nasal cavities.
CA2456502A 2001-08-16 2002-08-16 Pack containing medicament and dispensing device Expired - Lifetime CA2456502C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0120018.7 2001-08-16
GBGB0120018.7A GB0120018D0 (en) 2001-08-16 2001-08-16 Pack containing medicament and dispensing device
PCT/GB2002/003807 WO2003015857A1 (en) 2001-08-16 2002-08-16 Pack containing medicament and dispensing device

Publications (2)

Publication Number Publication Date
CA2456502A1 true CA2456502A1 (en) 2003-02-27
CA2456502C CA2456502C (en) 2010-10-12

Family

ID=9920532

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2456502A Expired - Lifetime CA2456502C (en) 2001-08-16 2002-08-16 Pack containing medicament and dispensing device

Country Status (20)

Country Link
US (2) US7401713B2 (en)
EP (1) EP1441790B1 (en)
JP (2) JP2004538105A (en)
KR (1) KR100922660B1 (en)
CN (2) CN1951356B (en)
AT (1) ATE397469T1 (en)
AU (1) AU2002321491B2 (en)
CA (1) CA2456502C (en)
CY (1) CY1108247T1 (en)
DE (1) DE60226994D1 (en)
DK (1) DK1441790T3 (en)
ES (1) ES2305275T3 (en)
GB (1) GB0120018D0 (en)
HK (1) HK1071082A1 (en)
HU (1) HU229124B1 (en)
IL (2) IL160368A0 (en)
MX (1) MXPA04001403A (en)
PT (1) PT1441790E (en)
RU (1) RU2286180C2 (en)
WO (1) WO2003015857A1 (en)

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CN1543366A (en) 2004-11-03
CA2456502C (en) 2010-10-12
AU2002321491C1 (en) 2003-03-03
JP4774111B2 (en) 2011-09-14
ATE397469T1 (en) 2008-06-15
GB0120018D0 (en) 2001-10-10
EP1441790B1 (en) 2008-06-04
RU2004107566A (en) 2005-03-10
JP2009195728A (en) 2009-09-03
DK1441790T3 (en) 2008-09-08
HUP0401029A3 (en) 2005-11-28
HU229124B1 (en) 2013-08-28
RU2286180C2 (en) 2006-10-27
CY1108247T1 (en) 2014-02-12
US20040206773A1 (en) 2004-10-21
CN1295000C (en) 2007-01-17
CN1951356B (en) 2010-05-19
ES2305275T3 (en) 2008-11-01
JP2004538105A (en) 2004-12-24
US20090321295A1 (en) 2009-12-31
WO2003015857A1 (en) 2003-02-27
CN1951356A (en) 2007-04-25
PT1441790E (en) 2008-07-28
HUP0401029A2 (en) 2004-09-28
EP1441790A1 (en) 2004-08-04
US7987985B2 (en) 2011-08-02
IL160368A (en) 2008-07-08
DE60226994D1 (en) 2008-07-17
KR20040036711A (en) 2004-04-30
AU2002321491B2 (en) 2006-02-09
MXPA04001403A (en) 2005-06-06
HK1071082A1 (en) 2005-07-08
KR100922660B1 (en) 2009-10-19
IL160368A0 (en) 2004-07-25
US7401713B2 (en) 2008-07-22

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