CA2459239A1 - Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment - Google Patents

Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment Download PDF

Info

Publication number
CA2459239A1
CA2459239A1 CA002459239A CA2459239A CA2459239A1 CA 2459239 A1 CA2459239 A1 CA 2459239A1 CA 002459239 A CA002459239 A CA 002459239A CA 2459239 A CA2459239 A CA 2459239A CA 2459239 A1 CA2459239 A1 CA 2459239A1
Authority
CA
Canada
Prior art keywords
castor oil
lipid
hydrogenated castor
topical ointment
pharmaceutically elegant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002459239A
Other languages
French (fr)
Other versions
CA2459239C (en
Inventor
David P. Jones
David W. Hobson
Pilar P. Duque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Healthpoint Ltd
Original Assignee
Healthpoint, Ltd.
David P. Jones
David W. Hobson
Pilar P. Duque
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healthpoint, Ltd., David P. Jones, David W. Hobson, Pilar P. Duque filed Critical Healthpoint, Ltd.
Publication of CA2459239A1 publication Critical patent/CA2459239A1/en
Application granted granted Critical
Publication of CA2459239C publication Critical patent/CA2459239C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Abstract

A topical ointment pharmaceutical composition that uses a lipophilic base, a pharmaceutical active and, dispersed in the base, from about 1 % to about 50 %
by weight of the total composition of hydrogenated non-melted castor oil in powder form. The result of using hydrogenated non-melted castor oil in powder form is a surprising pharmaceutical elegance perceived to be smoother in texture and more spreadable than an ointment made by melting the hydrogenated castor oil.
CA002459239A 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment Expired - Fee Related CA2459239C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/945,903 US6479060B1 (en) 2001-09-04 2001-09-04 Elegant hydrogenated castor oil ointments
US09/945,903 2001-09-04
PCT/US2002/023954 WO2003020203A2 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments

Publications (2)

Publication Number Publication Date
CA2459239A1 true CA2459239A1 (en) 2003-03-13
CA2459239C CA2459239C (en) 2005-06-14

Family

ID=25483673

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002459239A Expired - Fee Related CA2459239C (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment

Country Status (16)

Country Link
US (1) US6479060B1 (en)
EP (1) EP1423154B1 (en)
JP (1) JP4115391B2 (en)
KR (2) KR100638417B1 (en)
CN (1) CN100463697C (en)
AT (1) ATE413861T1 (en)
AU (1) AU2002330929B2 (en)
BR (1) BR0212286A (en)
CA (1) CA2459239C (en)
DE (1) DE60229855D1 (en)
DK (1) DK1423154T3 (en)
ES (1) ES2315400T3 (en)
HK (1) HK1065963A1 (en)
MX (1) MXPA04001969A (en)
PT (1) PT1423154E (en)
WO (1) WO2003020203A2 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
NZ540166A (en) 2002-10-25 2007-06-29 Foamix Ltd Cosmetic and pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US7785584B2 (en) * 2003-08-13 2010-08-31 Healthpoint, Ltd. Ointment wound spray
US20050048105A1 (en) * 2003-08-29 2005-03-03 Mcnulty Amy K. Protease inhibitor compositions for prevention and treatment of skin conditions
US20050100621A1 (en) * 2003-11-07 2005-05-12 Popp Karl F. Dermatological compositions
US20060264505A1 (en) * 2003-11-07 2006-11-23 Stiefel Laboratories, Inc. Dermatological compositions
US20050281806A1 (en) * 2004-06-16 2005-12-22 Collegium Pharmaceutical, Inc., Delaware Compositions for topical enzymatic debridement
US8211449B2 (en) * 2004-06-24 2012-07-03 Dpt Laboratories, Ltd. Pharmaceutically elegant, topical anhydrous aerosol foam
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
AR065378A1 (en) * 2007-02-16 2009-06-03 Procter & Gamble ABSORBENT ARTICLE WITH LOTION THAT INCLUDES A POLYPROPYLENE GLYCOL MATERIAL
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009090495A2 (en) * 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
CA2760186C (en) 2009-04-28 2019-10-29 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
KR101102857B1 (en) * 2009-08-07 2012-01-10 남연우 Kitchen container
WO2011138678A2 (en) * 2010-05-04 2011-11-10 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses thereof
BR112012007473A2 (en) 2009-10-02 2019-05-07 Foamix Ltd tetracycline topical compositions and methods of use
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
CA2782622C (en) 2009-12-08 2018-05-22 Healthpoint, Ltd. Enzymatic wound debriding compositions with enhanced enzymatic activity
US9011931B1 (en) 2011-01-26 2015-04-21 Libby Robinson Wound dressing composition and method of use
ES2742273T3 (en) * 2011-02-15 2020-02-13 Aclaris Therapeutics Inc Pharmaceutical oxymetazoline cream compositions to treat rosacea symptoms
BR112013028968A2 (en) 2011-05-12 2018-04-24 Smith & Nephew Orthopaedics Ag seaprose-containing wound debridement compositions and wound treatment methods using them
KR20150013280A (en) 2012-05-11 2015-02-04 스미스 앤드 네퓨, 인크. Use of seaprose to remove bacterial biofilm
US11628207B2 (en) 2016-07-27 2023-04-18 Smith & Nephew, Inc. Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
EP3573622B1 (en) 2017-01-30 2023-10-18 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
US20220395450A1 (en) * 2021-06-10 2022-12-15 Pauleine Prospere Hair Or Skin Treatment Composition And Methods Of Preparation And Use

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB892450A (en) * 1959-11-18 1962-03-28 Ici Ltd Improvements in or relating to pharmaceutical compositions comprising ethylthiocarbonyl compounds
US3314972A (en) * 1965-05-21 1967-04-18 Warner Lambert Pharmaceutical Indolo[3, 2-c]thiopyrylium compounds and intermediates therefor
US5021429A (en) * 1977-05-17 1991-06-04 Allen & Hansburys Limited Pharmacologically active aminoalkylphenyl compounds and their use
JPS546002A (en) * 1977-06-17 1979-01-17 Chuo Yuka Lithium soappbase lubricating grease compositions and production thereof
DE2924005C2 (en) 1979-06-13 1984-07-05 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Agent containing isosorbide dinitrate
NZ196700A (en) 1980-04-18 1983-04-12 Smith & Nephew Ass Anti-inflammatory compositions containing 5-benzoyl-1-methylpyrrole-2-acetic acid derivatives
US4334546A (en) * 1980-09-08 1982-06-15 Kolmar Laboratories Inc. Cosmetic pencil
US5102656A (en) 1983-07-29 1992-04-07 The Mennen Company Antiperspirant creams
DE3409720A1 (en) * 1984-03-16 1985-09-19 Bayer Ag, 5090 Leverkusen STRUCTURAL VISCOS SET SILICONE PASTE AND THEIR USE AS IMPRESSION MEASURES
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
IT1183530B (en) 1985-03-29 1987-10-22 Monteluos S P A COMPOSITIONS FOR COSMETICS INCLUDING PERFLUOROPOLYETERS
IT1197056B (en) * 1986-08-01 1988-11-25 Intercos Italiana POMATED TO MASK SKIN DEFECTS AND SCARS
EP0399432B1 (en) 1989-05-25 1994-06-22 Takeda Chemical Industries, Ltd. Transdermal therapeutic composition
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
WO1996011002A1 (en) 1994-10-05 1996-04-18 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory agent for external use
EP0793963A4 (en) 1994-10-24 2001-12-12 Nikken Chemicals Co Ltd Percutaneously administrable preparation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
JP4010574B2 (en) 1994-12-05 2007-11-21 電気化学工業株式会社 Topical skin preparation
RO113156B1 (en) * 1995-03-10 1998-04-30 Icerp Sa Lithium grease and process for producing the same
US6063762A (en) 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
US6267970B1 (en) * 1998-03-23 2001-07-31 Avon Products, Inc. Cream cosmetic base with powdery feel
IT1302275B1 (en) * 1998-09-25 2000-09-05 Giorgio Panin VITAMIN AND ACETATE HYDROPHOBIC GEL FORMULATION FOR TOPICAL APPLICATION.
US6262117B1 (en) * 1999-02-18 2001-07-17 Allergan Sales, Inc. Method and composition for treating acne

Also Published As

Publication number Publication date
JP4115391B2 (en) 2008-07-09
CN1610563A (en) 2005-04-27
DK1423154T3 (en) 2009-01-26
BR0212286A (en) 2006-05-23
MXPA04001969A (en) 2004-07-08
EP1423154B1 (en) 2008-11-12
HK1065963A1 (en) 2005-03-11
JP2005527468A (en) 2005-09-15
CN100463697C (en) 2009-02-25
KR20060086460A (en) 2006-07-31
EP1423154A4 (en) 2007-08-15
WO2003020203A2 (en) 2003-03-13
ES2315400T3 (en) 2009-04-01
KR100638417B1 (en) 2006-10-24
CA2459239C (en) 2005-06-14
US6479060B1 (en) 2002-11-12
ATE413861T1 (en) 2008-11-15
WO2003020203A3 (en) 2003-07-10
KR20040041597A (en) 2004-05-17
AU2002330929B2 (en) 2005-06-16
DE60229855D1 (en) 2008-12-24
KR100764278B1 (en) 2007-10-05
PT1423154E (en) 2009-01-30
EP1423154A2 (en) 2004-06-02

Similar Documents

Publication Publication Date Title
CA2459239A1 (en) Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment
CA2370565A1 (en) Dermally applicable vitamin d-containing pharmaceutical compositions
WO2003028703A3 (en) Immediate release tablet
WO2004066910A8 (en) Controlled release modifying complex and pharmaceutical compositions thereof
WO2005089729A3 (en) Galenic formulations of organic compounds
CA2291085A1 (en) Skin care compositions and method of improving skin appearance
CA2103443A1 (en) Chewable Drug-Delivery Composition
GB0007419D0 (en) Composition
AU2001263229A1 (en) Compositions and methods for administration of pharmacologically active compounds
AU2003274681A1 (en) Dosage form comprising high dose high soluble active ingredient as modified release and low dose active ingredient as immediate release
AU2002343191A1 (en) Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
EP1283054A4 (en) Drugs for complications of diabetes and neuropathy and utilization thereof
WO2005048979A3 (en) Pharmaceutical composition having casing with multiple micro tablets
AU2003282782A1 (en) Pharmaceutically active lipid based formulation of sn38
CA2367387A1 (en) Composition comprising isoquercetin and ascorbic acid in a sustained release form
CA2347195A1 (en) Oral pharmaceutical compositions containing buprenorphin
AU2002309038A1 (en) Compositions for transmucosal administration containing coenzyme Q as the active ingredient
IT1263840B (en) ORAL FORMULATIONS OF UBIDECARENONE IN THE FORM OF CAPSULES
CA2411882A1 (en) Solid valsartan pharmaceutical compositions
WO2002015959A3 (en) Compounds and compositions for delivering active agents
IL179544A0 (en) Compositions comprising flavonoids and tocotrienols and methods thereof
WO2002011694A3 (en) Compositions and dosage forms for application in the oral cavity in the treatment of mykoses
WO2008062475A3 (en) Pharmaceutical compositions of ursodiol
WO2002100404A3 (en) Pyridoxal in combination with serotonin re-uptake inhibitor for the treatment of hot flushes
WO2005115346A3 (en) Pharmaceutical composition containing risperidone

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150729