CA2459239A1 - Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment - Google Patents

Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment Download PDF

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Publication number
CA2459239A1
CA2459239A1 CA002459239A CA2459239A CA2459239A1 CA 2459239 A1 CA2459239 A1 CA 2459239A1 CA 002459239 A CA002459239 A CA 002459239A CA 2459239 A CA2459239 A CA 2459239A CA 2459239 A1 CA2459239 A1 CA 2459239A1
Authority
CA
Canada
Prior art keywords
castor oil
lipid
hydrogenated castor
topical ointment
pharmaceutically elegant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002459239A
Other languages
French (fr)
Other versions
CA2459239C (en
Inventor
David P. Jones
David W. Hobson
Pilar P. Duque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Healthpoint Ltd
Original Assignee
Healthpoint, Ltd.
David P. Jones
David W. Hobson
Pilar P. Duque
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healthpoint, Ltd., David P. Jones, David W. Hobson, Pilar P. Duque filed Critical Healthpoint, Ltd.
Publication of CA2459239A1 publication Critical patent/CA2459239A1/en
Application granted granted Critical
Publication of CA2459239C publication Critical patent/CA2459239C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Abstract

A topical ointment pharmaceutical composition that uses a lipophilic base, a pharmaceutical active and, dispersed in the base, from about 1 % to about 50 %
by weight of the total composition of hydrogenated non-melted castor oil in powder form. The result of using hydrogenated non-melted castor oil in powder form is a surprising pharmaceutical elegance perceived to be smoother in texture and more spreadable than an ointment made by melting the hydrogenated castor oil.
CA002459239A 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment Expired - Fee Related CA2459239C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/945,903 2001-09-04
US09/945,903 US6479060B1 (en) 2001-09-04 2001-09-04 Elegant hydrogenated castor oil ointments
PCT/US2002/023954 WO2003020203A2 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments

Publications (2)

Publication Number Publication Date
CA2459239A1 true CA2459239A1 (en) 2003-03-13
CA2459239C CA2459239C (en) 2005-06-14

Family

ID=25483673

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002459239A Expired - Fee Related CA2459239C (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment

Country Status (16)

Country Link
US (1) US6479060B1 (en)
EP (1) EP1423154B1 (en)
JP (1) JP4115391B2 (en)
KR (2) KR100638417B1 (en)
CN (1) CN100463697C (en)
AT (1) ATE413861T1 (en)
AU (1) AU2002330929B2 (en)
BR (1) BR0212286A (en)
CA (1) CA2459239C (en)
DE (1) DE60229855D1 (en)
DK (1) DK1423154T3 (en)
ES (1) ES2315400T3 (en)
HK (1) HK1065963A1 (en)
MX (1) MXPA04001969A (en)
PT (1) PT1423154E (en)
WO (1) WO2003020203A2 (en)

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US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
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US20060264505A1 (en) * 2003-11-07 2006-11-23 Stiefel Laboratories, Inc. Dermatological compositions
US20050100621A1 (en) * 2003-11-07 2005-05-12 Popp Karl F. Dermatological compositions
US20050281806A1 (en) * 2004-06-16 2005-12-22 Collegium Pharmaceutical, Inc., Delaware Compositions for topical enzymatic debridement
US8211449B2 (en) * 2004-06-24 2012-07-03 Dpt Laboratories, Ltd. Pharmaceutically elegant, topical anhydrous aerosol foam
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
AR065378A1 (en) * 2007-02-16 2009-06-03 Procter & Gamble ABSORBENT ARTICLE WITH LOTION THAT INCLUDES A POLYPROPYLENE GLYCOL MATERIAL
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
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CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
KR101102857B1 (en) * 2009-08-07 2012-01-10 남연우 Kitchen container
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
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US20130053353A1 (en) * 2010-05-04 2013-02-28 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses
US9011931B1 (en) 2011-01-26 2015-04-21 Libby Robinson Wound dressing composition and method of use
US20120208858A1 (en) * 2011-02-15 2012-08-16 Allergan, Inc. Pharmaceutical Cream Compositions of Oxymetazoline and Methods of Use
CA2835664C (en) 2011-05-12 2019-02-05 Smith & Nephew Orthopaedics Ag Wound debridement compositions containing seaprose and methods of wound treatment using same
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Also Published As

Publication number Publication date
KR100764278B1 (en) 2007-10-05
CN100463697C (en) 2009-02-25
JP2005527468A (en) 2005-09-15
AU2002330929B2 (en) 2005-06-16
ATE413861T1 (en) 2008-11-15
MXPA04001969A (en) 2004-07-08
EP1423154A4 (en) 2007-08-15
HK1065963A1 (en) 2005-03-11
DE60229855D1 (en) 2008-12-24
CN1610563A (en) 2005-04-27
PT1423154E (en) 2009-01-30
KR20060086460A (en) 2006-07-31
EP1423154B1 (en) 2008-11-12
ES2315400T3 (en) 2009-04-01
DK1423154T3 (en) 2009-01-26
CA2459239C (en) 2005-06-14
BR0212286A (en) 2006-05-23
JP4115391B2 (en) 2008-07-09
WO2003020203A3 (en) 2003-07-10
EP1423154A2 (en) 2004-06-02
KR100638417B1 (en) 2006-10-24
KR20040041597A (en) 2004-05-17
US6479060B1 (en) 2002-11-12
WO2003020203A2 (en) 2003-03-13

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Effective date: 20150729