CA2459867A1 - Adaptors for inhalers to improve performance - Google Patents

Adaptors for inhalers to improve performance Download PDF

Info

Publication number
CA2459867A1
CA2459867A1 CA002459867A CA2459867A CA2459867A1 CA 2459867 A1 CA2459867 A1 CA 2459867A1 CA 002459867 A CA002459867 A CA 002459867A CA 2459867 A CA2459867 A CA 2459867A CA 2459867 A1 CA2459867 A1 CA 2459867A1
Authority
CA
Canada
Prior art keywords
adaptor
inhaler
mouthpiece
flow sensor
attachment means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002459867A
Other languages
French (fr)
Other versions
CA2459867C (en
Inventor
Andrew L. Abrams
Anand V. Gumaste
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microdose Therapeutx Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2459867A1 publication Critical patent/CA2459867A1/en
Application granted granted Critical
Publication of CA2459867C publication Critical patent/CA2459867C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M16/101—Preparation of respiratory gases or vapours with O2 features or with parameter measurement using an oxygen concentrator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/18—General characteristics of the apparatus with alarm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/43—General characteristics of the apparatus making noise when used correctly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code

Abstract

A child-sized adaptor for a DPI or MDI is provided. Also provided is a patient feedback mechanism for signaling and/or teaching proper inhaler use.

Claims (17)

1. A mouthpiece adaptor for an inhaler comprising:
a connecting side for connecting to a mouthpiece of an inhaler;
a mouthpiece side of reduced size relative to the inhaler mouthpiece; and a transition section between said connecting side and mouthpiece side.
2. The adaptor of claim 1, further comprising attachment means for fixing the mouthpiece adaptor to the mouthpiece of an inhaler.
3. The adaptor of claim 2, wherein said attachment means is a clamp.
4. The adaptor of claim 1, wherein said inhaler is a dry powder inhaler.
5. The adaptor of claim 1, wherein said inhaler is a metered dose inhaler.
6. The adaptor of claim 2, wherein the attachment means employs a friction fit.
7. The adaptor of claim 1, wherein the connecting section is funnel shaped.
8. The adaptor of claim 3, wherein the mouthpiece side is round in cross-section.
9. The adaptor of claim 3, wherein the connecting section is covered, at least in part, by a foil.
10. The adaptor of claim 2, wherein said attachment means is a rubber band.
11. The adaptor of claim 1, wherein the transition section is curved.
12. The adaptor of claim 11, wherein said transition section is airfoil shaped, in part.
13. The adaptor of claim 1, wherein said adaptor includes a flow sensor.
14. The adaptor of claim 13, further comprising a noise generator operatively connected to said flow sensor.
15. The adaptor of claim 13, further comprising one or more lights operatively connected to said flow sensor.
16. An inhaler for delivering medication to the respiratory tract comprising a flow sensor for sensing the rate of inhalation and a feedback mechanism to transmit this information to the patient.
17. The patient feedback mechanism according to claim 16 is acoustic, visual or light in nature.
CA2459867A 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance Expired - Lifetime CA2459867C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31770601P 2001-09-06 2001-09-06
US60/317,706 2001-09-06
PCT/US2002/030308 WO2003022332A2 (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance

Publications (2)

Publication Number Publication Date
CA2459867A1 true CA2459867A1 (en) 2003-03-20
CA2459867C CA2459867C (en) 2012-03-13

Family

ID=23234910

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2459867A Expired - Lifetime CA2459867C (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance

Country Status (18)

Country Link
US (2) US7343914B2 (en)
EP (1) EP1446172B1 (en)
JP (1) JP4846976B2 (en)
KR (2) KR20040039327A (en)
CN (2) CN101239212A (en)
AT (1) ATE464083T1 (en)
AU (1) AU2002327052B2 (en)
CA (1) CA2459867C (en)
CY (1) CY1110147T1 (en)
DE (1) DE60236011D1 (en)
DK (1) DK1446172T3 (en)
ES (1) ES2343239T3 (en)
IL (1) IL160628A0 (en)
MX (1) MXPA04001859A (en)
NZ (1) NZ531614A (en)
PL (1) PL203183B1 (en)
PT (1) PT1446172E (en)
WO (1) WO2003022332A2 (en)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005044173A1 (en) * 2003-10-27 2005-05-19 Oriel Therapeutics, Inc. Blister packages and associated methods of fabricating dry powder drug containment systems
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
EP1718353B1 (en) * 2004-02-24 2019-12-11 MicroDose Therapeutx, Inc. Synthetic jet based medicament delivery apparatus
DE102004012093A1 (en) * 2004-03-05 2005-09-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler with Merkanaldüse
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
JP4948422B2 (en) * 2005-02-01 2012-06-06 インテリジェクト，インコーポレイテッド Drug delivery apparatus, system and method
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
DE102005010965B3 (en) * 2005-03-10 2006-08-03 Medspray Xmems Bv Medical inhaler for personal use, comprises a mixing channel with an outlet with a medicament injection area that is designed to be flush with the surface of the channel to less than a millimeter (mm) and ideally less than a tenth of a mm
EP1866016A4 (en) * 2005-03-30 2011-02-16 Canon Kk Liquid medicine ejection device
KR20080039503A (en) * 2005-08-22 2008-05-07 메디-스트림 피티와이 리미티드 Medication dispenser and carrier therefor
EP2357015A3 (en) 2006-04-05 2012-07-25 MicroDose Therapeutx, Inc. Variable dose inhalation device
US20080087279A1 (en) * 2006-10-11 2008-04-17 Tieck Catharine Laureen Johnso Metered dose inhaler
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
EP2534957B1 (en) 2007-12-14 2015-05-27 AeroDesigns, Inc Delivering aerosolizable products
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
AU2009286377A1 (en) * 2008-08-25 2010-03-04 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus which provides audio instructions
DE102008054431B3 (en) * 2008-12-09 2010-06-17 Pari Pharma Gmbh Aerosol therapy device
GB2468108A (en) * 2009-02-18 2010-08-25 Jaqueline Scott Asthma inhaler kit adapted to make sound upon inhalation and exhalation
EP2414560B1 (en) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Method for coating a surface of a component
EP2432531B1 (en) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalation device and nebulizer
CA2762819C (en) * 2009-05-21 2016-12-20 Microdose Therapeutx, Inc. Rotary cassette system for dry powder inhaler
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
US20110000481A1 (en) 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
US20130255678A1 (en) 2009-07-01 2013-10-03 Microdose Therapeutx, Inc. Nebulizer for infants and respiratory compromised patients
JP5658268B2 (en) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
MY187036A (en) * 2010-01-05 2021-08-27 Microdose Therapeutx Inc Inhalation device and method
JP5873805B2 (en) 2010-01-07 2016-03-01 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Respiratory medication delivery device including feedback and compliance device
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
GB201006736D0 (en) * 2010-04-22 2010-06-09 Mian Omar Gas flow indicator
US20110307039A1 (en) * 2010-06-14 2011-12-15 Cornell Thomas H Device, method and system for treatment of sinusitis
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
PL2654864T3 (en) 2010-12-22 2021-07-12 Syqe Medical Ltd. System for drug delivery
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
EP2694220B1 (en) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medical device comprising a container
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013036881A2 (en) 2011-09-07 2013-03-14 Syphase, Llc Dry powder inhalation device
WO2013152894A1 (en) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Atomiser with coding means
US20130269694A1 (en) * 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Inhaler controlled by mobile device
ES2821811T3 (en) 2012-06-25 2021-04-27 Gecko Health Innovations Inc Devices, systems and methods for monitoring compliance and patient interaction
WO2014053242A1 (en) 2012-10-04 2014-04-10 Boehringer Ingelheim International Gmbh System, method and use for training an inhalation process
CA2896708A1 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
US20140251321A1 (en) * 2013-03-07 2014-09-11 Jonah Henry Benson Inhaler mouthpiece
WO2014143173A1 (en) 2013-03-15 2014-09-18 Ciancone Chris V Inhaler spacer and storage apparatus
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (en) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizer
ES2885800T3 (en) 2013-08-28 2021-12-15 Gecko Health Innovations Inc Devices and systems to monitor compliance, devices and systems to monitor the use of consumable dispensers
US10272215B2 (en) * 2014-04-07 2019-04-30 Boehringer Ingelheim International Gmbh Inhalation training device and system for practicing of an inhalation process of a patient
DK3129087T3 (en) 2014-04-07 2020-05-25 Boehringer Ingelheim Int PROCEDURE, ELECTRONIC DEVICE, INHALATION TRAINING SYSTEM TO EXERCISE AND / OR CONTROL A PATIENT INHALATION PROCESS
DK3139984T3 (en) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Atomizer
US10576222B2 (en) 2014-05-07 2020-03-03 Boehringer Ingelheim International Gmbh Container, indicator device with moveable piercing part, and nebulizer
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
RU2690401C2 (en) 2014-06-30 2019-06-03 Сике Медикал Лтд. Method and device for evaporation and inhalation of released substances
WO2016001922A1 (en) 2014-06-30 2016-01-07 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
ES2736130T3 (en) 2014-06-30 2019-12-26 Syqe Medical Ltd Pharmacological dose cartridge for an inhaler device
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
PL3160565T3 (en) 2014-06-30 2022-01-10 Syqe Medical Ltd. Devices and systems for pulmonary delivery of active agents
US9993602B2 (en) * 2014-06-30 2018-06-12 Syqe Medical Ltd. Flow regulating inhaler device
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
CN107206199B (en) 2015-01-22 2021-02-09 皇家飞利浦有限公司 Inhalation aid for feature distribution
US11266347B2 (en) * 2015-01-23 2022-03-08 Novartis Ag Apparatus and method for producing a flow profile
US20210128848A1 (en) * 2015-07-15 2021-05-06 Prakash Mehta Inhaler mouthpiece device
US20170014584A1 (en) * 2015-07-15 2017-01-19 Prakash Mehta Inhaler mouthpiece
RU2738578C2 (en) 2015-07-20 2020-12-14 Перл Терапьютикс, Инк. Aerosol delivery systems and corresponding methods
EP3851102A1 (en) 2016-01-06 2021-07-21 Syqe Medical Ltd. Low dose therapeutic treatment
WO2017167737A1 (en) * 2016-03-31 2017-10-05 Chiesi Farmaceutici S.P.A. Aerosol inhalation device
CN115054786A (en) 2016-04-12 2022-09-16 生物合作制造公司 Metered dose inhaler attachment, observation enhancement system and method of improving observations in using metered dose inhalers
CN109310834B (en) * 2016-04-18 2021-07-06 励志私人有限公司 Spacer for an inhaler
GB2556016A (en) * 2016-06-20 2018-05-23 Smartair Medical Ltd Device for monitoring medication intake
WO2018071425A1 (en) 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
CN110290822A (en) * 2016-10-11 2019-09-27 微剂量治疗公司 Inhalator and its application method
WO2018136413A2 (en) 2017-01-17 2018-07-26 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
AU2018244582A1 (en) 2017-03-28 2019-09-19 Concentrx Pharmaceuticals, Inc. Devices and methods for delivering dry powder medicaments
CN110831647B (en) * 2017-04-18 2022-02-01 励志私人有限公司 Spacer for atomizer
CA3060820A1 (en) * 2017-04-18 2018-10-25 Inspiring Pty Ltd Dry powder inhaler and spacer device for a dry powder inhaler
CA2981322A1 (en) * 2017-10-03 2019-04-03 Smart Rs Inc. Improved adapter for drug delivery in a ventilator circuit
FR3081104B1 (en) * 2018-05-18 2020-05-15 Aptar France Sas FLUID PRODUCT DISPENSING DEVICE.
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2865370A (en) * 1957-09-06 1958-12-23 Birch & Gattone Inc Dispensing adaptor for disposable aerosol units
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US4470412A (en) 1982-03-19 1984-09-11 Trutek Research, Inc. Inhalation valve
US4581013A (en) * 1982-04-19 1986-04-08 Jane C. A. Hayes Doser for orally administering medicine
US4790305A (en) * 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
US4926852B1 (en) * 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
US4792333A (en) * 1986-11-04 1988-12-20 Strawdose, Inc. Unit dose drug package and administering device
US4832015A (en) 1988-05-19 1989-05-23 Trudell Medical Pediatric asthmatic inhaler
US5020527A (en) 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
US5363842A (en) 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
GB9203761D0 (en) 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
DE4208880A1 (en) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg SEPARATOR FOR POWDER INHALATORS
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
RU2071789C1 (en) * 1993-05-26 1997-01-20 Владимир Николаевич Абросимов Device for carrying out aerosol therapy
US5505195A (en) * 1993-09-16 1996-04-09 Medtrac Technologies Inc. Dry powder inhalant device with dosage and air flow monitor
SE9303155D0 (en) 1993-09-27 1993-09-27 Astra Ab Face mask
US6390088B1 (en) * 1993-12-13 2002-05-21 Boehringer Ingelheim Kg Aerosol inhaler
PT101450B (en) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos NEW INHALATION DEVICE
EP0667168B1 (en) * 1994-02-14 2000-06-21 Aradigm Corporation An inhalation training device
US5848588A (en) * 1994-05-25 1998-12-15 Trudell Medical Group Backpiece for receiving an MDI adapter in an aerosolization spacer
CA2124410A1 (en) * 1994-05-26 1995-11-27 Jean-Paul Praud Device for the simultaneous delivery of beta 2 agonists and oxygen to a patient
US5477849A (en) * 1994-05-31 1995-12-26 Fry; Stephen Spacer for medication inhaler
US5482030A (en) 1994-06-13 1996-01-09 Klein; David Aerosol and non-aerosol spray counter
GB9421687D0 (en) 1994-10-27 1994-12-14 Aid Medic Ltd Dosimetric spacer
US5522380A (en) * 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
US5571246A (en) * 1995-02-16 1996-11-05 Alldredge; Andrew L. Collapsible metered dose inhaler
GB9513218D0 (en) * 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
US5780058A (en) * 1995-07-21 1998-07-14 Alza Corporation Oral delivery of discrete units
US5746197A (en) * 1995-08-18 1998-05-05 Williams; Jeffery W. Extension for metered dose inhaler
AU7726096A (en) * 1995-11-15 1997-06-05 Regents Of The University Of Minnesota System for detecting target respiratory flow rates
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5839430A (en) * 1996-04-26 1998-11-24 Cama; Joseph Combination inhaler and peak flow rate meter
WO1997048496A1 (en) * 1996-06-21 1997-12-24 Hughes Technology Group L.L.C. Micro-atomizing device
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
GB9706121D0 (en) * 1997-03-25 1997-05-14 Bespak Plc Inhalation device
US5794612A (en) * 1997-04-02 1998-08-18 Aeromax Technologies, Inc. MDI device with ultrasound sensor to detect aerosol dispensing
US6085742A (en) * 1997-04-02 2000-07-11 Aeromax Technologies, Inc. Intrapulmonary delivery device
US6394085B1 (en) * 1997-09-25 2002-05-28 Norton Healthcare Ltd. Inhaler spacer
US6470882B1 (en) * 1997-09-29 2002-10-29 Michael T. Newhouse Pernasal application of aerosol medication
US5855202A (en) * 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US6014972A (en) * 1997-12-11 2000-01-18 Thayer Medical Corporation Dry drug particle delivery system and method for ventilator circuits
US6358058B1 (en) * 1998-01-30 2002-03-19 1263152 Ontario Inc. Aerosol dispensing inhaler training device
US6202643B1 (en) * 1998-02-23 2001-03-20 Thayer Medical Corporation Collapsible, disposable MDI spacer and method
USD412979S (en) * 1998-02-27 1999-08-17 Diemolding Corporation Metered dose inhaler spacer
CN2320270Y (en) * 1998-03-10 1999-05-26 王少廉 Oral-protecting spatula inhaling aid for quantitative aerosol
US6578571B1 (en) 1998-04-20 2003-06-17 Infamed Ltd. Drug delivery device and methods therefor
CN1202876C (en) 1998-06-12 2005-05-25 微量技术公司 Metering, packaging and delivery of pharmaceuticals and drugs
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
US6257231B1 (en) * 1998-12-03 2001-07-10 Ferraris Medical, Inc. Aerosol enhancement
US6202642B1 (en) * 1999-04-23 2001-03-20 Medtrac Technologies, Inc. Electronic monitoring medication apparatus and method
DE19944208C1 (en) * 1999-09-15 2001-09-06 Transmit Technologietransfer Combination mouthpiece for treating oxygen insufficiency in pulmonary hypertension and chronic obstructive pulmonary disease, comprises aerosol duct for supplying drug and inlet for receiving oxygen tube adapter
US6240917B1 (en) * 1999-12-20 2001-06-05 Joseph R. Andrade Aerosol holding chamber for a metered-dose inhaler
AU3500901A (en) * 2000-02-11 2001-08-20 Medic Aid Ltd Drug delivery apparatus
US20020000225A1 (en) * 2000-06-02 2002-01-03 Carlos Schuler Lockout mechanism for aerosol drug delivery devices
US6684880B2 (en) * 2001-12-04 2004-02-03 Hewlett-Packard Development Company, L.P. Applicator for dispensing bioactive compositions and methods for using the same

Also Published As

Publication number Publication date
WO2003022332A3 (en) 2004-06-03
US20080228099A1 (en) 2008-09-18
JP2005501664A (en) 2005-01-20
NZ531614A (en) 2006-07-28
AU2002327052B2 (en) 2007-10-18
EP1446172A2 (en) 2004-08-18
ES2343239T3 (en) 2010-07-27
PL373584A1 (en) 2005-09-05
US20030041859A1 (en) 2003-03-06
CN101239212A (en) 2008-08-13
DK1446172T3 (en) 2010-08-02
PT1446172E (en) 2010-05-06
PL203183B1 (en) 2009-09-30
US7343914B2 (en) 2008-03-18
WO2003022332A2 (en) 2003-03-20
ATE464083T1 (en) 2010-04-15
CN1551788A (en) 2004-12-01
CN100374171C (en) 2008-03-12
DE60236011D1 (en) 2010-05-27
MXPA04001859A (en) 2004-06-15
EP1446172B1 (en) 2010-04-14
EP1446172A4 (en) 2005-07-20
IL160628A0 (en) 2004-07-25
JP4846976B2 (en) 2011-12-28
KR20090038043A (en) 2009-04-17
CA2459867C (en) 2012-03-13
KR100998394B1 (en) 2010-12-03
KR20040039327A (en) 2004-05-10
CY1110147T1 (en) 2015-01-14
WO2003022332B1 (en) 2004-07-15

Similar Documents

Publication Publication Date Title
CA2459867A1 (en) Adaptors for inhalers to improve performance
JP2005501664A5 (en)
US8371304B2 (en) Continuous positive airway pressure device and method
US5765553A (en) Aerosol medication delivery facemask adapter
US6253766B1 (en) Continuous positive airway pressure therapy device
JP6002686B2 (en) System for providing ventilation to individuals
JP6293760B2 (en) Breathing mask
EP4252811A3 (en) Breathing assistance apparatus
US20090165799A1 (en) Continuous positive airway pressure device
WO2002034322A3 (en) Sealed back pressure breathing device
WO2002068031A3 (en) Nasal delivery devices
JP2002512092A5 (en)
TW200607538A (en) Medicament inhaler device
JP2007511297A5 (en)
AU2002327052A1 (en) Adaptors for inhalers to improve performance
WO2004096110A3 (en) Pursed lip breathing device
EP3294394B1 (en) Liquid removal in a patient interface assembly
HK1080703A1 (en) Ventilation apparatus for pulmonary scintigraphy
EP1224003B8 (en) Combination mouthpiece for inhalation therapy devices used by oxygen dependent patients
ATE443534T1 (en) ASTHMA MEDICINE INHALER WITH WHISTLE
CN201596202U (en) Medical aerosol inhalator
EP1747791B1 (en) Asthma preparation inhaler auxiliary device with reed
CN218652054U (en) Medical mouth piece convenient for breathing and air injection input
CN219462238U (en) Anesthesia mask
CN215608463U (en) Medical mask

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20220906