CA2465502A1 - Pneumatic powered autoinjector - Google Patents
Pneumatic powered autoinjector Download PDFInfo
- Publication number
- CA2465502A1 CA2465502A1 CA002465502A CA2465502A CA2465502A1 CA 2465502 A1 CA2465502 A1 CA 2465502A1 CA 002465502 A CA002465502 A CA 002465502A CA 2465502 A CA2465502 A CA 2465502A CA 2465502 A1 CA2465502 A1 CA 2465502A1
- Authority
- CA
- Canada
- Prior art keywords
- medicament
- needle
- force
- viscous
- dispenser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/482—Varying injection pressure, e.g. by varying speed of injection
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K17/00—Safety valves; Equalising valves, e.g. pressure relief valves
- F16K17/20—Excess-flow valves
- F16K17/22—Excess-flow valves actuated by the difference of pressure between two places in the flow line
- F16K17/24—Excess-flow valves actuated by the difference of pressure between two places in the flow line acting directly on the cutting-off member
- F16K17/28—Excess-flow valves actuated by the difference of pressure between two places in the flow line acting directly on the cutting-off member operating in one direction only
- F16K17/30—Excess-flow valves actuated by the difference of pressure between two places in the flow line acting directly on the cutting-off member operating in one direction only spring-loaded
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D7/00—Control of flow
- G05D7/01—Control of flow without auxiliary power
- G05D7/0126—Control of flow without auxiliary power the sensing element being a piston or plunger associated with one or more springs
- G05D7/0133—Control of flow without auxiliary power the sensing element being a piston or plunger associated with one or more springs within the flow-path
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/282—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Abstract
The present invention provides a pneumatic injector that includes a pressurized gas source, an actuator, a driver, and a dispenser. The dispenser of the injector includes a reservoir for containing a desired amount of a chosen medicament and a needle, such as a hypodermic needle, suitable for subcutaneous, intramuscular, or intra-articular delivery of the chosen medicament. The actuator actuates the transmission of pressurized gas from the pressurized gas source to the driver, and as pressurized gas is delivered to the driver, the driver exerts at least an injection force. The injection force is of sufficient magnitude to expel a chosen medicament through the needle of the dispenser within a desired amount of time. Advantageously, the design of the injector of the present invention is extremely flexible, allowing the injector to the designed to deliver a wide range of medicaments in virtually any human or veterinary context calling for the injection of the subcutaneous, intramuscular, or intra-articular injection of medicament.
Claims (26)
1. A device for injecting a viscous medicament comprising a needle suitable for injecting the medicament, wherein the gauge of the needle is equal to or greater than about 21 gauge and the device is configured to drive the viscous medicament through the needle with sufficient force to cause injection of the medicament.
2. The device of claim 1, further comprising a pressurized gas source, an actuator, a driver, and a dispenser, wherein the pressurized gas source, the driver, and the dispenser are configured to inject the viscous medicament through the needle upon triggering the actuator.
3. The device of claim 1, wherein the viscous medicament has a viscosity greater than about 5 poise.
4. The device of claim 1, wherein the viscous medicament has a viscosity greater than about 10 poise.
5. The device of claim 1, wherein the viscous medicament has a viscosity greater than about 50 poise.
6. The device of claim 1, wherein the viscous medicament has a viscosity greater than about 100 poise.
7. The device of claim 2, wherein the driver comprises a multistage piston configured to exert at least a first force and a second force against the dispenser.
8. The device of claim 2, wherein the driver comprises a multistage piston configured to exert a first force and a second force against the dispenser, the second force being greater than the first force.
9. The device of claim 8, wherein the multistage piston is configured such that the first force is less than or equal to about 7 lbs and the second force is sufficient to inject the viscous medicament through the needle.
10. The device of claim 1, wherein the gauge of the needle ranges from about 27 gauge to about 31 gauge.
11. The device of claim 1, wherein the device is configured to inject up to about 0.5 cc of the viscous medicament through the needle within about 10 seconds.
12. The device of claim 1, wherein the device is configured to inject up to about 0.5 cc of the viscous medicament through the needle within about 5 seconds.
13. The device of claim 2, wherein the dispenser comprises a reservoir and the needle and the pressurized gas source, multistage piston, and dispenser are configured to inject up to about 0.5 cc of the viscous medicament through the needle within about 10 seconds
14. The device of claim 13, wherein the pressurized gas source, multistage piston, and dispenser are configured to expel up to about 0.5 cc of the viscous medicament through the needle within about 5 seconds.
15. A method for injecting a viscous medicament, the method comprising:
providing a viscous medicament;
providing a needle for injecting the viscous medicament, the needle having a needle gauge that is equal to or greater than about 21 gauge; and injecting the viscous medicament through the needle.
providing a viscous medicament;
providing a needle for injecting the viscous medicament, the needle having a needle gauge that is equal to or greater than about 21 gauge; and injecting the viscous medicament through the needle.
16. The method according to claim 15, wherein providing the viscous medicament comprises providing a medicament exhibiting a viscosity equal to or greater than about 5 poise.
17. The method according to claim 15, wherein providing the viscous medicament comprises providing a medicament exhibiting a viscosity equal to or greater than about 10 poise.
18. The method according to claim 15, wherein providing the viscous medicament comprises providing a medicament exhibiting a viscosity equal to or greater than about 50 poise.
19. The method according to claim 15, wherein providing the viscous medicament comprises providing a medicament exhibiting a viscosity equal to or greater than about 100 poise.
20. The method according to claim 15, wherein providing the needle comprises providing a needle having a needle gauge equal to or greater than about 27 gauge.
21. The method according to claim 15, wherein providing the needle comprises providing a needle having a needle gauge equal to about 31 gauge.
22. A device for injecting a medicament comprising:
a trigger;
a dispenser comprising a reservoir containing the medicament and a needle for injecting the medicament; and a driver comprising a multistage piston, the device for injecting the medicament being configured such that, upon actuation of the trigger, the multistage piston exerts at least a first force and a second force against the dispenser.
a trigger;
a dispenser comprising a reservoir containing the medicament and a needle for injecting the medicament; and a driver comprising a multistage piston, the device for injecting the medicament being configured such that, upon actuation of the trigger, the multistage piston exerts at least a first force and a second force against the dispenser.
23. The device of claim 22, further comprising a pressurized gas source and wherein the device is configured such that actuation of the trigger causes pressurized gas from the pressurized gas source to act against the multistage piston.
24. The device of claim 22, wherein the multistage piston of the device is configured to exert a first force that is less than a second force.
25. The device of claim 24, wherein the multistage piston of the device is configured such that the first force is exerted prior to exertion of the second force.
26. The device of claim 22, wherein each stage of the multistage piston is characterized by a different surface area.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33775301P | 2001-11-09 | 2001-11-09 | |
US60/337,753 | 2001-11-09 | ||
PCT/US2002/035978 WO2003039634A1 (en) | 2001-11-09 | 2002-11-08 | Pneumatic powered autoinjector |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2465502A1 true CA2465502A1 (en) | 2003-05-15 |
CA2465502C CA2465502C (en) | 2011-03-22 |
Family
ID=23321842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2465502A Expired - Fee Related CA2465502C (en) | 2001-11-09 | 2002-11-08 | Pneumatic powered autoinjector |
Country Status (24)
Country | Link |
---|---|
US (1) | US7654983B2 (en) |
EP (2) | EP1441787B2 (en) |
JP (1) | JP4771508B2 (en) |
KR (1) | KR100900158B1 (en) |
CN (1) | CN1315544C (en) |
AR (1) | AR037305A1 (en) |
AT (1) | ATE473023T1 (en) |
AU (1) | AU2002363335B2 (en) |
BR (1) | BR0214026A (en) |
CA (1) | CA2465502C (en) |
DE (1) | DE60236949D1 (en) |
DK (1) | DK2221076T3 (en) |
ES (2) | ES2408971T3 (en) |
HK (1) | HK1147449A1 (en) |
HU (1) | HU226575B1 (en) |
IL (2) | IL161301A0 (en) |
MX (1) | MXPA04004462A (en) |
NO (1) | NO332994B1 (en) |
NZ (1) | NZ532147A (en) |
PT (2) | PT1441787E (en) |
SI (1) | SI2221076T1 (en) |
TW (2) | TWI224517B (en) |
WO (1) | WO2003039634A1 (en) |
ZA (1) | ZA200404551B (en) |
Families Citing this family (150)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1476210B1 (en) | 2002-02-11 | 2008-09-24 | Antares Pharma, Inc. | Intradermal injector |
AU2003205326A1 (en) * | 2003-01-24 | 2004-08-23 | Alza Corporation | Pneumatic powered autoinjector |
GB2414405B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
GB2414399B (en) | 2004-05-28 | 2008-12-31 | Cilag Ag Int | Injection device |
GB2414409B (en) | 2004-05-28 | 2009-11-18 | Cilag Ag Int | Injection device |
GB2414403B (en) | 2004-05-28 | 2009-01-07 | Cilag Ag Int | Injection device |
GB2414402B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
GB2414406B (en) | 2004-05-28 | 2009-03-18 | Cilag Ag Int | Injection device |
GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
GB2414401B (en) | 2004-05-28 | 2009-06-17 | Cilag Ag Int | Injection device |
US7648483B2 (en) * | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US7947017B2 (en) | 2004-11-22 | 2011-05-24 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
JP4960252B2 (en) | 2004-11-22 | 2012-06-27 | インテリジェクト,インコーポレイテッド | Device, system and method for drug delivery |
US7648482B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems, and methods for medicament delivery |
US11590286B2 (en) | 2004-11-22 | 2023-02-28 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
US10737028B2 (en) | 2004-11-22 | 2020-08-11 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
JP5216328B2 (en) | 2005-01-24 | 2013-06-19 | アンタレス ファーマ インコーポレイテッド | Pre-filled needle assist syringe jet injector |
ES2396745T3 (en) | 2005-02-01 | 2013-02-25 | Intelliject, Inc. | Devices for medication administration |
US7731686B2 (en) | 2005-02-01 | 2010-06-08 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US8231573B2 (en) | 2005-02-01 | 2012-07-31 | Intelliject, Inc. | Medicament delivery device having an electronic circuit system |
US8206360B2 (en) * | 2005-02-01 | 2012-06-26 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
US9022980B2 (en) * | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
GB2425062B (en) | 2005-04-06 | 2010-07-21 | Cilag Ag Int | Injection device |
GB2424838B (en) | 2005-04-06 | 2011-02-23 | Cilag Ag Int | Injection device (adaptable drive) |
GB2427826B (en) | 2005-04-06 | 2010-08-25 | Cilag Ag Int | Injection device comprising a locking mechanism associated with integrally formed biasing means |
GB2424836B (en) | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
GB2424835B (en) | 2005-04-06 | 2010-06-09 | Cilag Ag Int | Injection device (modified trigger) |
CA2610592A1 (en) * | 2005-06-16 | 2006-12-28 | Artes Medical, Inc. | Liquid crystal polymer syringes and containers and methods of use for long term storage of filler materials |
US20070055199A1 (en) | 2005-08-10 | 2007-03-08 | Gilbert Scott J | Drug delivery device for buccal and aural applications and other areas of the body difficult to access |
DE602005018480D1 (en) | 2005-08-30 | 2010-02-04 | Cilag Gmbh Int | Needle device for a prefilled syringe |
US20110098656A1 (en) | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
WO2007131025A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Injector with adjustable dosing |
US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
GB2438590B (en) | 2006-06-01 | 2011-02-09 | Cilag Gmbh Int | Injection device |
GB2438593B (en) | 2006-06-01 | 2011-03-30 | Cilag Gmbh Int | Injection device (cap removal feature) |
GB2438591B (en) | 2006-06-01 | 2011-07-13 | Cilag Gmbh Int | Injection device |
GB2438592B (en) * | 2006-06-01 | 2011-04-06 | Cilag Gmbh Int | Injection device |
US20080097378A1 (en) * | 2006-08-02 | 2008-04-24 | Zuckerman Stephen D | Optical device for needle placement into a joint |
US20090124996A1 (en) * | 2006-11-03 | 2009-05-14 | Scott Heneveld | Apparatus and methods for injecting high viscosity dermal fillers |
US20080114309A1 (en) * | 2006-11-13 | 2008-05-15 | Zuckerman Stephen D | Acoustic device for needle placement into a joint |
WO2008091838A2 (en) | 2007-01-22 | 2008-07-31 | Intelliject, Inc. | Medical injector with compliance tracking and monitoring |
WO2009047247A1 (en) * | 2007-10-10 | 2009-04-16 | Shl Group Ab | Medical delivery device |
WO2009086250A1 (en) * | 2007-12-21 | 2009-07-09 | Aesthetic Sciences Corporation | Self-contained pressurized injection device |
EP2268342B1 (en) | 2008-03-10 | 2015-09-16 | Antares Pharma, Inc. | Injector safety device |
USD994111S1 (en) | 2008-05-12 | 2023-08-01 | Kaleo, Inc. | Medicament delivery device cover |
US8021344B2 (en) | 2008-07-28 | 2011-09-20 | Intelliject, Inc. | Medicament delivery device configured to produce an audible output |
US8052645B2 (en) | 2008-07-23 | 2011-11-08 | Avant Medical Corp. | System and method for an injection using a syringe needle |
MX2010012691A (en) | 2008-05-20 | 2011-03-30 | Avant Medical Corp Star | Autoinjector system. |
US8177749B2 (en) | 2008-05-20 | 2012-05-15 | Avant Medical Corp. | Cassette for a hidden injection needle |
GB2461086B (en) | 2008-06-19 | 2012-12-05 | Cilag Gmbh Int | Injection device |
GB2461087B (en) | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
GB2461085B (en) | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
DE102008030270A1 (en) | 2008-06-19 | 2009-12-24 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Device having at least one chamber for receiving a medicament or a sample volume |
GB2461084B (en) | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Fluid transfer assembly |
GB2461089B (en) | 2008-06-19 | 2012-09-19 | Cilag Gmbh Int | Injection device |
ES2738539T3 (en) | 2008-08-05 | 2020-01-23 | Antares Pharma Inc | Multi dose injector |
WO2010108116A1 (en) | 2009-03-20 | 2010-09-23 | Antares Pharma, Inc. | Hazardous agent injection system |
CA2756972A1 (en) * | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Medical device having a mechanism and use of a low-friction synthetic material within a medical device |
WO2011022618A1 (en) * | 2009-08-21 | 2011-02-24 | Becton Dickinson France Sas | Pre-filled active vial having integral plunger assembly |
CA2774586A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Method and assembly for a drug delivery device |
TWI619521B (en) * | 2009-12-15 | 2018-04-01 | 艾伯維生物技術有限責任公司 | Automatic injection device, automatic injection method and method for preventing misfiring |
EP2438945A1 (en) * | 2010-10-08 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Reusable engine for an auto-injector |
US20120271272A1 (en) | 2010-10-15 | 2012-10-25 | Iscience Interventional Corporation | Device for ocular access |
CN103370092B (en) * | 2011-01-10 | 2016-09-28 | 周吉尼克斯股份有限公司 | Needleless injector |
US9084849B2 (en) | 2011-01-26 | 2015-07-21 | Kaleo, Inc. | Medicament delivery devices for administration of a medicament within a prefilled syringe |
US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
AU2015255197B2 (en) * | 2011-01-26 | 2019-03-28 | Kaleo, Inc. | Medicament delivery devices for administration of a medicament within a prefilled syringe |
US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US10092706B2 (en) | 2011-04-20 | 2018-10-09 | Amgen Inc. | Autoinjector apparatus |
JP5793346B2 (en) * | 2011-05-31 | 2015-10-14 | 日立オートモティブシステムズ株式会社 | Cylinder device |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
PL2574357T3 (en) * | 2011-09-28 | 2014-04-30 | Q Med Ab | Electronic injector |
US10058657B2 (en) | 2011-11-07 | 2018-08-28 | Eli Lilly And Company | Injection devices with ergonomic enhancements |
JP6165786B2 (en) | 2012-03-06 | 2017-07-19 | アンタレス・ファーマ・インコーポレーテッド | Filling syringe with release force feature |
KR20150011346A (en) | 2012-04-06 | 2015-01-30 | 안타레스 팔마, 인코퍼레이티드 | Needle assisted jet injection administration of testosterone compositions |
USD898908S1 (en) | 2012-04-20 | 2020-10-13 | Amgen Inc. | Pharmaceutical product cassette for an injection device |
USD808010S1 (en) | 2012-04-20 | 2018-01-16 | Amgen Inc. | Injection device |
WO2013163088A1 (en) * | 2012-04-23 | 2013-10-31 | Zogenix, Inc. | Piston closures for drug delivery capsules |
WO2013169800A1 (en) | 2012-05-07 | 2013-11-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
GB201210082D0 (en) * | 2012-06-07 | 2012-07-25 | Consort Medical Plc | Improved syringe |
US8920374B2 (en) * | 2012-07-05 | 2014-12-30 | Unitract Syringe Pty Ltd | Drive control mechanisms and automatic injectors for injectable cartridges |
CA2887471C (en) * | 2012-10-11 | 2018-05-15 | Carebay Europe Ltd | Automatic injection training device |
EA031645B1 (en) | 2012-10-12 | 2019-02-28 | Эли Лилли Энд Компани | Chemical engine |
US9321581B2 (en) | 2012-10-12 | 2016-04-26 | Eli Lilly And Company | Process and device for delivery of fluid by chemical reaction |
US9675754B2 (en) * | 2012-10-24 | 2017-06-13 | Nuance Designs, LLC | Autoinjector |
US20140121699A1 (en) * | 2012-10-31 | 2014-05-01 | Nordson Corporation | Device and method for dispensing a liquid and a gas |
WO2014106096A1 (en) | 2012-12-27 | 2014-07-03 | Kaleo, Inc. | Devices, systems and methods for locating and interacting with medicament delivery systems |
CA2900672C (en) | 2013-02-11 | 2018-03-27 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
JP6030803B2 (en) | 2013-03-11 | 2016-11-24 | アンタレス・ファーマ・インコーポレーテッド | Dose syringe with pinion system |
WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
US10092703B2 (en) | 2013-03-15 | 2018-10-09 | Amgen Inc. | Drug cassette, autoinjector, and autoinjector system |
EP2968771A4 (en) | 2013-03-15 | 2017-02-15 | University Hospitals Case Medical Center | Subcutaneous hydration system, method, and device |
EP3593839A1 (en) | 2013-03-15 | 2020-01-15 | Amgen Inc. | Drug cassette |
AU2014259694B2 (en) | 2013-05-03 | 2018-11-08 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
GB2515038A (en) | 2013-06-11 | 2014-12-17 | Cilag Gmbh Int | Injection device |
GB2515039B (en) | 2013-06-11 | 2015-05-27 | Cilag Gmbh Int | Injection Device |
GB2515032A (en) | 2013-06-11 | 2014-12-17 | Cilag Gmbh Int | Guide for an injection device |
GB2517896B (en) | 2013-06-11 | 2015-07-08 | Cilag Gmbh Int | Injection device |
BR112015033068B1 (en) | 2013-07-01 | 2022-05-31 | Credence Medsystems Inc | SAFETY SYRINGE |
GB2519970B (en) * | 2013-11-01 | 2017-06-14 | Consort Medical Plc | Medicament delivery device sub-assembly |
EP3068473B1 (en) * | 2013-11-15 | 2019-09-04 | Credence Medsystems Inc. | System and method for drug delivery with a safety syringe |
WO2015119906A1 (en) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
CA2943721C (en) | 2014-03-26 | 2021-06-08 | L.O.M. Laboratories Inc. | Gas release cell |
US10872313B2 (en) | 2015-06-02 | 2020-12-22 | ROCA Medical Ltd. | Method for repurposing NDC codes in a pharmaceutical database for venom derived allergens involved in venom immunotherapy |
IL298454A (en) | 2014-04-24 | 2023-01-01 | Credence Medsystems Inc | System and method for safety syringe |
RU2710491C2 (en) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Device for drug injection into ocular tissue and method for drug injection into ocular tissue |
US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
CA2977060C (en) | 2015-02-20 | 2023-09-05 | Regeneron Pharmaceuticals, Inc. | Syringe systems, piston seal systems, stopper systems, and methods of use and assembly |
AU2016235138B2 (en) * | 2015-03-26 | 2018-07-26 | Enable Injections, Inc | Pressurized gas powered medicament transfer and re-suspension apparatus and method |
GB2537639B (en) | 2015-04-21 | 2020-09-23 | Consort Medical Plc | Medicament delivery device |
EP3093035A1 (en) * | 2015-05-13 | 2016-11-16 | Sanofi-Aventis Deutschland GmbH | Injection device for delivery of a liquid medicament |
US10548974B2 (en) | 2015-06-02 | 2020-02-04 | ROCA Medical Ltd. | Therapeutic treatment kit for allergies based on DNA profiles |
WO2017004345A1 (en) | 2015-06-30 | 2017-01-05 | Kaleo, Inc. | Auto-injectors for administration of a medicament within a prefilled syringe |
MX2018000667A (en) | 2015-08-26 | 2018-04-24 | Halliburton Energy Services Inc | Sol-gel modified particulates for wellbore fluids. |
CZ306565B6 (en) | 2015-11-20 | 2017-03-08 | ChemProtect.SK s.r.o. | An autoinjector |
GB2545266B (en) * | 2015-12-11 | 2018-08-08 | Oval Medical Tech Limited | Autoinjector with retracting needle |
CH712384A2 (en) | 2016-04-21 | 2017-10-31 | Tecpharma Licensing Ag | Gas release device for use in an injection device. |
JP7008345B2 (en) * | 2016-04-29 | 2022-01-25 | アルタヴィズ,リミティッド・ライアビリティ・カンパニー | Self-excited syringe |
JP2019514581A (en) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | Systems and methods for ocular drug delivery |
US10328205B2 (en) | 2016-07-07 | 2019-06-25 | Shl Medical Ag | Drug delivery device with pneumatic power pack |
WO2018011249A1 (en) * | 2016-07-14 | 2018-01-18 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
US10709845B2 (en) | 2016-07-21 | 2020-07-14 | Amgen Inc. | Drug delivery device with a rotatable drive mechanism |
IL305537A (en) | 2016-08-12 | 2023-10-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
US20180117252A1 (en) * | 2016-11-02 | 2018-05-03 | Portal Instruments, Inc. | Encoding information for drug delivery |
JP7014797B2 (en) | 2016-12-23 | 2022-02-01 | カレオ,インコーポレイテッド | Drug delivery devices and methods for delivering drugs to babies and children |
US9636460B1 (en) | 2016-12-28 | 2017-05-02 | Creare Llc | Pneumatic autoinjector with automated mixing |
WO2018136413A2 (en) * | 2017-01-17 | 2018-07-26 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and event detection |
GB2559553B (en) * | 2017-02-06 | 2021-10-13 | Consort Medical Plc | A medicament delivery device |
CN110312540B (en) | 2017-02-17 | 2022-04-05 | 伊莱利利公司 | Method and device for transporting fluids by chemical reaction |
JP7408398B2 (en) | 2017-07-14 | 2024-01-05 | アムジエン・インコーポレーテツド | Needle insertion and retraction system with dual torsion spring system |
US11890453B2 (en) * | 2017-11-04 | 2024-02-06 | Altaviz, Llc | Injection devices and methods for making and using them |
KR20200085284A (en) * | 2017-11-04 | 2020-07-14 | 알타비즈 엘엘씨 | Gas driven fluid injection system |
CN111417423B (en) * | 2017-11-04 | 2022-10-11 | 奥特威资有限责任公司 | Injection device and methods of making and using the same |
US11951286B2 (en) | 2018-06-12 | 2024-04-09 | Banza Stamping Industry Corp. | Automatic injection device for fluid |
TWI679998B (en) * | 2018-06-12 | 2019-12-21 | 邦查工業股份有限公司 | Automatic injection device for fluid |
US10905830B2 (en) | 2018-06-12 | 2021-02-02 | Banza Stamping Industry Corp. | Automatic injection device for fluid |
WO2020018433A1 (en) | 2018-07-16 | 2020-01-23 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and compliance detection |
EP3627034B1 (en) * | 2018-09-21 | 2021-10-27 | Goodrich Corporation | Valve |
WO2020086752A1 (en) * | 2018-10-23 | 2020-04-30 | Aktivax, Inc. | Intranasal pressure drug delivery device |
EP4009936A4 (en) | 2019-08-09 | 2023-08-09 | Kaleo, Inc. | Devices and methods for delivery of substances within a prefilled syringe |
CN112402741B (en) * | 2020-10-09 | 2023-05-05 | 杭州远滴科技有限公司 | Intermittent clutch type injection medicine driving device with automatic sensing unit |
EP4326816A1 (en) * | 2021-04-20 | 2024-02-28 | Celanese International Corporation | Polymer composition with mold release properties |
KR102630826B1 (en) * | 2021-10-18 | 2024-01-29 | 주식회사 파인메딕스 | Hemostatic spray |
WO2023107515A1 (en) * | 2021-12-06 | 2023-06-15 | Altaviz, Llc | Gas powered auto-injectors and methods for use |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5781A (en) | 1848-09-19 | Improvement in posts for telegraphs | ||
DE902776C (en) | 1949-08-17 | 1954-01-28 | August Rooseboom | Automatic injection device with ampoule |
US3055362A (en) † | 1956-05-16 | 1962-09-25 | Auguste Rooseboom | Hypodermic injection apparatus |
US3403679A (en) | 1964-12-11 | 1968-10-01 | Secr Defence Brit | Hypodermic injection apparatus with a secondary capsule-collapsing means |
US3688765A (en) * | 1969-10-03 | 1972-09-05 | Jack S Gasaway | Hypodermic injection device |
BE795162A (en) | 1972-02-10 | 1973-08-08 | Philips Nv | INJEKTIE-INRICHTING |
US4031889A (en) * | 1975-03-25 | 1977-06-28 | William Floyd Pike | Power operated aspirating hypodermic syringe |
US4108176A (en) | 1977-02-25 | 1978-08-22 | Agri-Bio Corporation | Automatic injecting apparatus |
HU189198B (en) | 1982-12-10 | 1986-06-30 | Adorjan,Andras,Hu | Plastic syringe for single use as well as plastic piston particularly for plastic syringes |
HU186718B (en) | 1983-06-29 | 1985-09-30 | Radelkis Electrokemiai | Automatic needleless syringe operable by cardox cylinder suitable for personal giving injection e.g. insulin |
HU195428B (en) | 1987-02-17 | 1988-05-30 | Fegyver Es Gazkeszuelekgyar | Needleless vaccinating instrument of adjustable injection depth operable by hand-power |
US4790824A (en) * | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
JPS6417654U (en) | 1987-07-22 | 1989-01-27 | ||
US4894054A (en) | 1988-06-20 | 1990-01-16 | Miskinyar Shir A | Preloaded automatic disposable syringe |
US5066276A (en) * | 1988-06-21 | 1991-11-19 | Alcon Laboratories, Inc. | Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control |
GB8926825D0 (en) | 1989-11-28 | 1990-01-17 | Glaxo Group Ltd | Device |
US5352196A (en) | 1990-11-19 | 1994-10-04 | Habley Medical Technology Corporation | Mixing vial |
US5176645A (en) | 1991-05-01 | 1993-01-05 | Diana Corporation | Pneumatic, modular device for dispensing medication to animals |
GB9111600D0 (en) | 1991-05-30 | 1991-07-24 | Owen Mumford Ltd | Improvements relating to injection devices |
GB9125699D0 (en) | 1991-12-03 | 1992-01-29 | Glaxo Group Ltd | Device |
EP0598867B1 (en) * | 1992-06-15 | 1997-03-05 | WYSSMANN, Max | Device for the intentional and controllable distribution of a liquid or visquous material |
US5383851A (en) * | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
IT1256577B (en) | 1992-12-11 | 1995-12-11 | Ermanno Greco | DEVICE PREPARED FOR THE AUTOMATIC ADMINISTRATION OF A DRUG VIA INTRADERMIC. |
US5695472A (en) | 1993-05-27 | 1997-12-09 | Washington Biotech Corporation | Modular automatic or manual emergency medicine injection system |
US5425715A (en) | 1993-08-05 | 1995-06-20 | Survival Technology, Inc. | Reloadable injector |
HU214350B (en) | 1993-12-13 | 1998-03-30 | Mom Invest Kft. | Vaccinating device without needle |
FR2715071B1 (en) | 1994-01-17 | 1996-03-01 | Aguettant Lab | Automatic drug injector. |
AUPM922394A0 (en) | 1994-11-03 | 1994-11-24 | Astra Pharmaceuticals Pty Ltd | Plastic syringe with overcap |
US5792099A (en) * | 1995-02-14 | 1998-08-11 | Decamp; Dennis | Syringe and cannula for insertion of viscoelastic material into an eye and method of using same |
GB9515846D0 (en) | 1995-08-02 | 1995-10-04 | Boc Group Plc | Gas capsule |
WO2000071185A2 (en) | 1999-05-19 | 2000-11-30 | Weston Medical Ltd | Needleless injector drug capsule |
CA2209406C (en) | 1996-07-24 | 2007-05-15 | David W. Birch | Gas capsule and gas delivery system |
GB9716065D0 (en) | 1997-07-31 | 1997-10-01 | Owen Mumford Ltd | Improvements relating to injection devices |
US5957896A (en) | 1997-08-11 | 1999-09-28 | Becton, Dickinson And Company | Medication delivery pen |
DK1047343T3 (en) | 1998-01-12 | 2004-11-01 | Alsensa Aps | An injector |
SE9803662D0 (en) † | 1998-10-26 | 1998-10-26 | Pharmacia & Upjohn Ab | autoinjector |
US6569123B2 (en) | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Prefillable intradermal injector |
FR2805749B1 (en) | 2000-03-01 | 2002-05-17 | Poudres & Explosifs Ste Nale | NEEDLELESS SYRINGE AT TWO LEVELS OF INJECTION SPEED |
JP2005516646A (en) | 2001-11-09 | 2005-06-09 | アルザ・コーポレーシヨン | Syringe cartridge related case that can be dented |
-
2002
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- 2002-11-08 BR BR0214026-8A patent/BR0214026A/en not_active Application Discontinuation
- 2002-11-08 SI SI200231026T patent/SI2221076T1/en unknown
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