CA2479145A1 - Medication dispenser with consistent dispensing - Google Patents

Medication dispenser with consistent dispensing Download PDF

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Publication number
CA2479145A1
CA2479145A1 CA002479145A CA2479145A CA2479145A1 CA 2479145 A1 CA2479145 A1 CA 2479145A1 CA 002479145 A CA002479145 A CA 002479145A CA 2479145 A CA2479145 A CA 2479145A CA 2479145 A1 CA2479145 A1 CA 2479145A1
Authority
CA
Canada
Prior art keywords
source
dispenser
spout
locator
junction member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002479145A
Other languages
French (fr)
Other versions
CA2479145C (en
Inventor
John Raymond Bacon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clinical Designs Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0206811A external-priority patent/GB0206811D0/en
Priority claimed from GB0227489A external-priority patent/GB0227489D0/en
Application filed by Individual filed Critical Individual
Publication of CA2479145A1 publication Critical patent/CA2479145A1/en
Application granted granted Critical
Publication of CA2479145C publication Critical patent/CA2479145C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/16—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means
    • B65D83/20—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means operated by manual action, e.g. button-type actuator or actuator caps
    • B65D83/205—Actuator caps, or peripheral actuator skirts, attachable to the aerosol container
    • B65D83/206—Actuator caps, or peripheral actuator skirts, attachable to the aerosol container comprising a cantilevered actuator element, e.g. a lever pivoting about a living hinge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/913—Breathable liquids

Abstract

A dispenser (1) comprises a can (2) and a body (3). The can is an aluminium extrusion with a valve crimped into its mouth, the valve having an outlet spout (4). The crimped region (5) of the can surrounding the valve has a lesser diameter than the can has through the main part (6) of its length. The body has a mouthpiece (11) with a pivotal cover (12) drivingly connected to a cam (13). This bears on the underside of a junction member (14), into a socket (15) of which the spout 4 fits. A breath actuated dose release mechanism (16) is provided. The body has a tubular section (7) for receiving the necked down region (5) of the can. The tubular section and the main part of the can having the same external diameter. A printed paper label (21) coated with self-adhesive is wrapped around the joint between the body and the can to unite the can to the body in position such that when the cover is opened, a dose is dispensed by the cam (13) lifting the junction member and depressing the spout. In order to establish correct positioning of the can with respect to the body, prior to positioning of the label, a predetermined force (F) is applied to ensure that the spout is fully depressed. This causes the can to release into the release mechanism a dose, which will usually be a metered dose. Thus in this position of the can in the body, when the cover is opened in use, another dose will be released. With the force still applied the label is applied to the can and the body fixing their relative position.

Claims (32)

1. A dispenser for a gaseous, gas borne or droplet substance contained in a source thereof, the dispenser comprising:
.cndot. a substance source having:
.cndot. an external surface devoid of any feature intended for longitudinal location of the source and .cndot. a spout displaceable inwards of the source to a dispense position for dispensing a substance dose from the source;
.cndot. a body having:
.cndot. a mouthpiece via which the substance dose can be inhaled and .cndot. a socket sized for lateral location of the source via its external surface, but devoid of any body feature intended for longitudinal location thereof;
.cndot. a junction member for the spout, the junction member being arranged in the body to be slidable to a set position for displacing the spout to its dispense position;
.cndot. an action for slidably moving the junction member to the set position;
and .cndot. a unification of the source or a source locator to the body for locating the source longitudinally with the spout in its dispense position when the junction member is in its set position, the locator where provided extending from the body, outside the source and at least partially across the end of the source to provide a longitudinal location for the source, locating it when the movable junction member acts to depress the spout inwards of the source.
2. A dispenser as claimed in claim 1, including a breath actuation mechanism for releasing the junction member from its set position, whereby the dose is released to the patient and the spout returns from its dispense position to its normal position.
3. A dispenser as claimed in claim 1 or claim 2, wherein the action for sliding the junction member to its set position is adapted to actuate the mechanism in the absence of a simulated breath to return the spout and the junction member to their normal positions.
4. A dispenser as claimed in any preceding claim, wherein the unification is of adhesive between the source or the locator and the body
5. A dispenser as claimed in claim 4, wherein the adhesive is in the socket of the body.
6. A dispenser as claimed in claim 4 or claim 5, wherein the body and/or the source or the locator have a re-entrant feature and the body or the locator has an aperture communicating with the re-entrant feature through which the adhesive was injected.
7. A dispenser as claimed in claim 6, wherein the re-entrant feature is an internal groove in the body or the locator for receiving the adhesive for a bond with the source or the body respectively.
8. A dispenser as claimed in claim 6, wherein the re-entrant feature is an external groove in the source at a crimp for retaining the spout and the source proper.
9. A dispenser as claimed in claim 1, claim 2 or claim 3, wherein the unification is a weld between the source or the locator and the body.
10. A dispenser as claimed in claim 9, wherein weld is an ultrasonic weld or a laser weld.
11. A dispenser as claimed in claim 9 or claim 10, wherein the source and/or the locator and the body are of plastics material.
12. A dispenser as claimed in claim 9 or claim 10, wherein the source is of glass or metal and is coated with plastics material.
13. A dispenser as claimed in claim 9 or claim 10 wherein the source is of un-coated glass or metal.
14. A dispenser as claimed in any one of claims 9 to 13, wherein the weld is between a container of the source and the body.
15. A dispenser as claimed in any one of claims 9 to 13, wherein the weld is between a ferrule of the source and the body.
16. A dispenser as claimed in any one of claims 9 to 13, wherein the weld is between source locator and the body.
17. A dispenser as claimed in any preceding claim, wherein the unification is a membrane around both the source or the locator and the body and unified to both.
18. A dispenser as claimed in claim 17, wherein the membrane is a wrapping.
19. A dispenser as claimed in claim 17, wherein the membrane is a printed label.
20. A dispenser as claimed in claim 17, claim 18 or claim 19, wherein the membrane is of paper.
21. A dispenser as claimed in claim 17, claim 18 or claim 19, wherein the membrane is of plastics material.
22. A dispenser as claimed in any one of claims 17 to 21, wherein the membrane is circumferentially continuous around the body.
23. A dispenser as claimed in claim 17, wherein the membrane is a shrink wrapping.
24. A dispenser as claimed in any one of claims 17 to 21, wherein the membrane is discontinuous around the source or the locator and the body.
25. A dispenser as claimed in claim 24, wherein two or more separate membranes could be used, one to one side of the source or the locator and the body and the other to the other side.
26. A dispenser as claimed in any one of claims 17 to 25, wherein the or each membrane has self-adhesive applied to it
27. A dispenser as claimed in any one of claims 17 to 25, wherein the or each membrane is of self adhesive material.
28. A dispenser as claimed in any one of claims 17 to 25, wherein adhesive for the membrane is applied directly to the source or the locator and the body.
29. A dispenser as claimed in any one of claims 17 to 25, wherein the source or the locator and/or the body are contoured to enhance the grip of the membrane to them.
30. A method in the production of a dispenser as claimed in any one of claims 1 to 29, the method consisting in the steps of:
.cndot. arranging the junction member in the body at its set;
.cndot. longitudinally assembling the source to the body, with the spout engaged with the junction member;
.cndot. temporarily holding the body and the source in a unification position with the spout in its dispense position and the junction member still in its set position;
and .cndot. unifying the body and the source together to fix them in their unified position.
31. A method as claimed in claim 31, wherein the dispenser includes a breath actuation mechanism for releasing the junction member from its set position, whereby the dose is released to the patient and the spout returns from its dispense position to its normal position, the unification step being followed by a simulated breath actuation.
32. A method as claimed in claim 31 or claim 32, wherein the source and the body are relatively located in the temporary holding step by urging the source towards the junction member with a force sufficient to depress the spout towards the source proper and dispense a dose of the substance to the junction member.
CA2479145A 2002-03-22 2003-03-17 Medication dispenser with consistent dispensing Expired - Fee Related CA2479145C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0206811.2 2002-03-22
GB0206811A GB0206811D0 (en) 2002-03-22 2002-03-22 Source mixture
GB0227489A GB0227489D0 (en) 2002-11-26 2002-11-26 Source fixture
GB0227489.2 2002-11-26
PCT/GB2003/001102 WO2003080161A1 (en) 2002-03-22 2003-03-17 Can fixture

Publications (2)

Publication Number Publication Date
CA2479145A1 true CA2479145A1 (en) 2003-10-02
CA2479145C CA2479145C (en) 2011-06-14

Family

ID=28456026

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2479145A Expired - Fee Related CA2479145C (en) 2002-03-22 2003-03-17 Medication dispenser with consistent dispensing

Country Status (17)

Country Link
US (1) US7814900B2 (en)
EP (2) EP2143458B1 (en)
JP (1) JP4422794B2 (en)
CN (1) CN100406078C (en)
AU (1) AU2003212529B2 (en)
BR (1) BR0303652A (en)
CA (1) CA2479145C (en)
CY (2) CY1119179T1 (en)
DK (2) DK1487523T3 (en)
ES (2) ES2636622T3 (en)
GB (1) GB2401321B (en)
HU (2) HUE033735T2 (en)
MX (1) MXPA04009152A (en)
NO (1) NO334928B1 (en)
PT (2) PT1487523T (en)
SI (2) SI2143458T1 (en)
WO (1) WO2003080161A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0328859D0 (en) * 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
WO2005087299A1 (en) 2004-03-10 2005-09-22 Glaxo Group Limited A dispensing device
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
US7350520B1 (en) 2004-12-03 2008-04-01 Linda C Richard-Bey Nebulizer delivery device
GB0428204D0 (en) 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
GB0518355D0 (en) 2005-09-08 2005-10-19 Glaxo Group Ltd An inhaler
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
US8123082B2 (en) 2008-01-22 2012-02-28 McNeil-AB Hand-held dispensing device
JP5339794B2 (en) * 2008-07-04 2013-11-13 キヤノン株式会社 Inhaler
GB0904040D0 (en) * 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB2471646B (en) 2009-05-11 2011-08-10 Consort Medical Plc Improvements in or relating to dispensing devices
US10016568B2 (en) * 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
GB201118842D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser cap arrangement
GB201118845D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser
GB201702408D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods

Family Cites Families (209)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB161969A (en) 1921-04-18 1922-07-18 Johannes Bretschneider Inhaler
DE629163C (en) 1934-01-04 1936-04-23 Leyland And Birmingham Rubber Valve for hollow bodies with flexible valve hose that can be closed by kinking
US2002835A (en) * 1934-05-11 1935-05-28 William H Rose Siphon device
US2716013A (en) * 1948-11-24 1955-08-23 Theodore B Tinker Flexible valve structure
US2922613A (en) * 1951-06-01 1960-01-26 Cutter Lab Pinch valve
US2773631A (en) 1952-01-16 1956-12-11 Paul M Bryant Measuring and dispensing devices for containers
CH297931A (en) 1952-04-01 1954-04-15 Nationale Sa Tube-burner for liquefied gas lighter.
US2771631A (en) 1953-11-12 1956-11-27 Hartford Nat Bank & Trust Comp Apparatus for recovery of crab meat
CH365596A (en) 1957-09-14 1962-11-15 Gauthier Gmbh A Machine tool with workpiece carrier that can be switched by one full turn
US2974835A (en) * 1959-02-12 1961-03-14 Milton B Herbrick Self-sealing receptacle closure
FR78023E (en) 1960-07-04 1962-05-26 Bruneau & Cie Lab Flow control device in a deformable tube
US3103335A (en) 1961-03-28 1963-09-10 Resiflex Lab Inc Unitary clamp means for flexible tubes
US3181743A (en) * 1961-06-19 1965-05-04 Sidney M Libit Dispensing closures of the collapsible wall type
US3190497A (en) * 1962-05-28 1965-06-22 Warner Lambert Pharmaceutical Liquid collecting apparatus and a valve therefor
GB1012565A (en) 1962-06-13 1965-12-08 Goddard & Sons Ltd J Improvements in or relating to liquid flow control valves
NL297349A (en) 1962-08-31
BE639537A (en) 1962-11-05
US3187748A (en) * 1963-04-29 1965-06-08 Merck And Company Inc Inhalation-actuated aerosol device
US3329389A (en) * 1964-03-09 1967-07-04 Plastronics Inc Valve for controlling flow through a flexible tube
US3395838A (en) * 1965-03-01 1968-08-06 Valve Corp Of America Manually operable dispenser valve
US3305144A (en) * 1965-03-01 1967-02-21 Valve Corp Of America Dispenser for disposable aerosol container, with valved conduit for remote dischargeof its contents
US3294293A (en) 1965-11-29 1966-12-27 Lever Brothers Ltd Closure-actuator for container with flexible tubular spout
US3456646A (en) * 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3456644A (en) 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3439846A (en) * 1967-06-26 1969-04-22 David J Evras Nonleak,nonspillable bottle cap
NL6904702A (en) 1968-03-26 1969-09-30
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3605738A (en) 1969-06-20 1971-09-20 Paul J Ciranna Medicinal spray device
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
GB1383761A (en) * 1971-02-25 1974-02-12 Woodcraft Dc Inhalation device for use with an aerosol container
NO134730L (en) * 1971-07-19 1900-01-01
US3789943A (en) * 1971-10-12 1974-02-05 Int Harvester Co Vehicle drive and power control means
IT970102B (en) 1972-10-31 1974-04-10 Crnospital Spa MICRO DOSING DEVICE FOR REGULATING THE FLOW OF FLUIDS IN FLEXIBLE HOSES
US3927484A (en) * 1974-02-04 1975-12-23 Gilbreth Co Die-cut coupon shrink label
US3926339A (en) 1974-06-21 1975-12-16 Nat Can Corp Liquid dispensing apparatus having plural can piercing tools
US3926347A (en) 1974-07-10 1975-12-16 Jaclo Inc Flowable material dispenser with resilient container
US4085886A (en) * 1977-01-03 1978-04-25 The Procter & Gamble Company Reclosable twin-Z-fold dispensing valve construction for a liquid containing film pouch
US4109836A (en) 1977-02-10 1978-08-29 Anna Falarde Self-sealing paste dispensing device
US4142651A (en) * 1977-04-29 1979-03-06 Norbert Leopoldi Fluid dispenser with flexible outlet tube and pinching valve
JPS5682322A (en) * 1979-12-10 1981-07-06 Tokai:Kk Valve device for gas lighter
DE8116061U1 (en) 1980-05-30 1981-11-19 Fumakilla Ltd., Tokyo "SPRAYER"
EP0045419B1 (en) 1980-08-04 1984-10-17 FISONS plc Inhalation device for administering medicaments
US4354660A (en) 1981-02-02 1982-10-19 Baxter Travenol Laboratories Inc. In-line flow control clamp
US4393884A (en) * 1981-09-25 1983-07-19 Jacobs Allen W Demand inhaler for oral administration of tobacco, tobacco-like, or other substances
CH663829A5 (en) * 1982-03-15 1988-01-15 Alfred Staeubli CATHETER VALVE.
DE3324699C1 (en) 1983-07-08 1984-12-06 B. Braun Melsungen Ag, 3508 Melsungen Valve device
US4576157A (en) * 1983-10-24 1986-03-18 Raghuprasad Puthalath K Oral inhalation apparatus
GB8328808D0 (en) * 1983-10-28 1983-11-30 Riker Laboratories Inc Inhalation responsive dispensers
WO1985002346A1 (en) 1983-11-28 1985-06-06 Vortran Corporation Gas-powered nebulizer
US4648393A (en) * 1984-11-02 1987-03-10 Ackrad Laboratories, Inc. Breath activated medication spray
US5042526A (en) 1984-12-03 1991-08-27 Kulakoff Alexander E Valveless toilet
US4972830A (en) 1985-07-31 1990-11-27 Vortran Medical Technology, Inc. Inhalation device and method
US4803978A (en) * 1985-08-09 1989-02-14 Johnson Iv John J Apparatus for actuating an inhaler
US4707038A (en) 1986-01-08 1987-11-17 Voegeli Ronald C Display rack
NZ219021A (en) 1986-01-27 1989-06-28 Gea Farmaceutisk Fabrik As Inhaler: medicine discharged intermittently during each inhalation
EP0242494B1 (en) 1986-04-23 1989-05-17 Ake Timerdahl A valve arrangement for controlling the supply of pressurized-air, water and/or other media to hand-operated tools, preferably instruments for dental work
NO871709L (en) * 1986-04-25 1987-10-26 Glaxo Group Ltd Indicating device.
US4703761A (en) 1986-08-04 1987-11-03 Rathbone R Rodion Blood sampling device for obtaining small quantity of venous blood
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
BR8802287A (en) 1987-05-12 1988-12-13 Glaxo Inc INHALATION DEVICE
US5031610A (en) * 1987-05-12 1991-07-16 Glaxo Inc. Inhalation device
US5119806A (en) * 1987-05-12 1992-06-09 Glaxo Inc. Inhalation device
DE3734894C1 (en) 1987-10-15 1989-01-26 Braun Melsungen Ag Attachment with valve
DE8715223U1 (en) 1987-11-17 1988-02-04 Bundesrepublik Deutschland, Vertreten Durch Den Bundesminister Der Verteidigung, Dieser Vertreten Durch Den Praesidenten Des Bundesamtes Fuer Wehrtechnik Und Beschaffung, 5400 Koblenz, De
GB8810898D0 (en) 1988-05-09 1988-06-15 Bespak Plc Improvements in dispensing apparatus
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
US5299701A (en) * 1989-02-03 1994-04-05 Senetics, Inc. Indicator cap
US5421482A (en) * 1989-02-03 1995-06-06 Senetics, Inc. Indicator device responsive to axial force
US5193745A (en) * 1989-03-07 1993-03-16 Karl Holm Atomizing nozzle device for atomizing a fluid and an inhaler
GB8909891D0 (en) * 1989-04-28 1989-06-14 Riker Laboratories Inc Device
EP0705614B1 (en) 1989-04-28 2002-09-25 Riker Laboratories, Inc. Dry powder inhalation device
US4955371A (en) 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US5297542A (en) * 1989-06-22 1994-03-29 Raymond J. Bacon Aerosol dispensing device
GB8914383D0 (en) 1989-06-22 1989-08-09 Bell Susan J Inhalation-actuated aerosol dispensing device
US5042685A (en) 1989-08-10 1991-08-27 Moulding Jr Thomas S Dispensing having a compartment for detecting and counting the dispensed objects especially adapted for dispensing medication and method of using the same
GB8919131D0 (en) * 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
GB8925707D0 (en) 1989-11-14 1990-01-04 Riker Laboratories Inc Device
FR2654627B1 (en) 1989-11-23 1992-02-28 Micro Mega Sa FLOW REGULATING DEVICE, PARTICULARLY FOR MEDICAL OR DENTAL USE.
US5152456A (en) 1989-12-12 1992-10-06 Bespak, Plc Dispensing apparatus having a perforate outlet member and a vibrating device
FR2658081B1 (en) * 1990-02-09 1995-06-30 Pesenti Yvan AUTOMATION AND SYNCHRONIZATION DEVICE FOR AEROSOL APPARATUS WITH DOSING PUMP.
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
US5020527A (en) 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
FR2660630B1 (en) 1990-04-10 1993-06-04 Bielsteiner France DEVICE FOR DISPENSING A FLUID OR PASTY PRODUCT CONTAINED IN A CRUSHABLE TUBE.
EP0461281A1 (en) 1990-06-12 1991-12-18 Atochem North America, Inc. Device for detecting air flow through a passageway
GB9015077D0 (en) 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
US5060643A (en) 1990-08-07 1991-10-29 Tenax Corporation Breath-activated inhalation device
GB9020555D0 (en) * 1990-09-20 1990-10-31 Bespak Plc Dispensing apparatus
GB9024760D0 (en) * 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
US5217004A (en) * 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
US5487378A (en) * 1990-12-17 1996-01-30 Minnesota Mining And Manufacturing Company Inhaler
DE4105939A1 (en) 1991-02-26 1992-08-27 Sigismund Laskowski METHOD AND DEVICE FOR DOSING LIQUID SUBSTANCES FROM A DISPENSING CONTAINER
US5404871A (en) 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
DE4111895C2 (en) 1991-04-12 1994-10-13 Sigismund Laskowski Method and device for closing and pouring liquid substances
BR9106690A (en) * 1991-04-15 1993-06-29 Huhtamaeki Yhthymae Oy PROVISION TO MEASURE A DOSE OF PULVERULENT DRUGS FOR INHALATION AND INHALATION APPARATUS EQUIPPED WITH THE SAME
FR2676929B1 (en) 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse POWDER INHALER.
DE4136985C1 (en) 1991-11-11 1993-05-13 Marsteller & Killmann Gmbh & Co Kg, 4300 Essen, De
US5469843A (en) 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
GB2262452B (en) 1991-12-19 1995-12-20 Minnesota Mining & Mfg Inhalation device
DE4142238A1 (en) * 1991-12-20 1993-06-24 Boehringer Ingelheim Kg POWDER INHALATOR WITH POWDER SUPPORT FROM REGULAR MICROSTRUCTURES
WO1993018812A1 (en) 1992-03-25 1993-09-30 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
GB2266466B (en) 1992-04-08 1995-12-20 Bespak Plc Inhalation apparatus
SE9201411D0 (en) 1992-05-05 1992-05-05 Astra Ab DOSAGE INHALATOR WITH INDICATING / INTERUPTING MEANS
GB2263873A (en) 1992-05-29 1993-08-11 Norton Healthcare Ltd Medicament dispensing device
GB2264238A (en) 1992-05-29 1993-08-25 Norton Healthcare Ltd Medicament inhalor device
GB9214819D0 (en) * 1992-07-13 1992-08-26 Minnesota Mining & Mfg Valve assemblies
GB9217545D0 (en) * 1992-08-18 1992-09-30 Minnesota Mining & Mfg Inhalation device
US5402823A (en) * 1992-12-07 1995-04-04 George S. Cole & Associates, Incorporated Pinch valve
WO1994016970A1 (en) * 1993-01-19 1994-08-04 Glaxo Group Limited Device
FR2701399B1 (en) 1993-02-16 1995-03-31 Valois Portable spray device with actuation triggered by inhalation.
FR2701653B1 (en) 1993-02-18 1995-04-07 Valois Dosing device for the inhalation of dry powder.
DE4313319B4 (en) 1993-04-23 2006-09-28 C. Ehrensperger Ag Device for actuators for propellant cans
GB2279571A (en) 1993-06-14 1995-01-11 Minnesota Mining & Mfg Inhaler
GB9312494D0 (en) 1993-06-17 1993-08-04 Lilly Industries Ltd Improvements in or relating to devices for dispensing articles
GB2279879B (en) 1993-07-14 1997-10-08 Bespak Plc Medicament inhalers
US5415161A (en) * 1993-09-15 1995-05-16 Ryder; Steven L. Intermittant demand aerosol control device
JPH09502951A (en) * 1993-09-22 1997-03-25 セネティクス，インコーポレイテッド A display that responds to axial forces
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5370279A (en) 1994-03-03 1994-12-06 Tardif; Pierre Squeeze canteen for dispensing a liquid
US5839429A (en) 1994-03-25 1998-11-24 Astra Aktiebolag Method and apparatus in connection with an inhaler
US5501375A (en) * 1994-05-12 1996-03-26 Cenova Innovations & Produktions Ab Dispenser valve for dispensing a pressurized liquid
US5564414A (en) 1994-05-26 1996-10-15 Walker; William F. Pressurized and metered medication dose counter on removable sleeve
FR2721106B1 (en) 1994-06-10 1996-09-13 Step Dose counter for inhalers.
US5857275A (en) * 1994-06-30 1999-01-12 Deal; Richard E. Label with enhanced grip
GB2292891A (en) 1994-09-07 1996-03-13 Norton Healthcare Ltd Actuator for breath-actuated medicament dispenser
US5544647A (en) 1994-11-29 1996-08-13 Iep Group, Inc. Metered dose inhalator
CA2213442A1 (en) * 1995-03-10 1996-09-19 The Minnesota Mining & Manufacturing Company Aerosol valves
US6205999B1 (en) * 1995-04-05 2001-03-27 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
USD377215S (en) * 1995-04-13 1997-01-07 Glaxo Group Limited Inhaler
US5809997A (en) 1995-05-18 1998-09-22 Medtrac Technologies, Inc. Electronic medication chronolog device
US5667142A (en) 1995-05-30 1997-09-16 Newstripe, Inc. Spray gun with removable supply line
AU128811S (en) * 1995-06-06 1996-12-03 Orion Yhtymae Oy A protective cover for example a moisture protective cover for a powder inhaler
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
US6357442B1 (en) * 1995-06-08 2002-03-19 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIS)
US6672304B1 (en) * 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19525546C2 (en) * 1995-07-13 2002-05-02 Schott Glas Device for the administration of substances, in particular inhalation preparations
DE29511334U1 (en) * 1995-07-13 1995-11-02 Schott Glaswerke Device for the administration of substances, in particular inhalation preparations
US5823183A (en) 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
JP3317823B2 (en) 1995-08-11 2002-08-26 株式会社ユニシアジェックス Dosing device
DE19549033C1 (en) 1995-12-28 1997-05-28 Boehringer Ingelheim Int Mechanical counter for a dosing device
BR9707660A (en) * 1996-02-21 2001-10-30 Schering Corp Powder medication inhaler
FR2750780B1 (en) * 1996-07-05 1998-10-30 Valois DOSER COUNTER
US5707038A (en) * 1996-10-23 1998-01-13 Cocatre-Zilgien; Jan H. Hinged kink valve
US6427683B1 (en) 1997-01-17 2002-08-06 Bo Drachmann Aerosol inhaler device
GB9705657D0 (en) * 1997-03-19 1997-05-07 Bacon Raymond J Dispenser
US5904139A (en) * 1997-03-28 1999-05-18 Hauser; Stephen G. Breath coordinated inhaler
US5794612A (en) 1997-04-02 1998-08-18 Aeromax Technologies, Inc. MDI device with ultrasound sensor to detect aerosol dispensing
US6085742A (en) * 1997-04-02 2000-07-11 Aeromax Technologies, Inc. Intrapulmonary delivery device
EP0984805B1 (en) * 1997-05-23 2004-11-10 PA Knowledge Limited Inhaler mechanism
TW533865U (en) 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
WO1999004843A1 (en) 1997-07-28 1999-02-04 Dr. Japan Co., Ltd. Mandrin of medical anesthetic needle and method of manufacturing same
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
DE19745513A1 (en) 1997-10-15 1999-04-22 Walz Karl Heinz Bottle valve system
AU776816B2 (en) 1997-10-17 2004-09-23 Systemic Pulmonary Delivery, Ltd. Method and apparatus for delivering aerosolized medication
WO1999036115A2 (en) 1998-01-16 1999-07-22 1263152 Ontario Inc. Indicating device for use with a dispensing device
FR2775668B1 (en) * 1998-03-04 2000-05-19 Tebro DEVICE FOR DISPENSING FLUID PRODUCT TRIGGERED BY INHALATION
NZ506289A (en) 1998-03-16 2004-12-24 Nektar Therapeutics Aerosolized active agent delivery to the lungs at a flow rate of less than 17 liters per minute
SE9801077D0 (en) 1998-03-27 1998-03-27 Shl Medical Ab Inhaler
GB9807558D0 (en) 1998-04-09 1998-06-10 Bason Neil P An indicator device
US6082358A (en) * 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6152130A (en) 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE29814647U1 (en) 1998-08-14 1999-12-23 Wischerath Josef Gmbh Co Kg Inhaler with a metering device
CA2344382C (en) * 1998-09-24 2008-01-29 Astrazeneca Ab Inhaler
DE29818662U1 (en) 1998-10-20 2000-03-02 Wischerath Josef Gmbh Co Kg inhaler
GB9825118D0 (en) 1998-11-16 1999-01-13 Minnesota Mining & Mfg Breath-actuated aerosol dispensers
GB2344534B (en) * 1998-12-11 2000-10-18 Bespak Plc Inhalation apparatus
AU140816S (en) 1999-01-29 2000-06-08 Glaxo Group Ltd Inhalation device
US6196218B1 (en) 1999-02-24 2001-03-06 Ponwell Enterprises Ltd Piezo inhaler
GB2348928B (en) * 1999-04-07 2001-10-31 Bespak Plc Improvements in or relating to dispensing apparatus
US6202642B1 (en) * 1999-04-23 2001-03-20 Medtrac Technologies, Inc. Electronic monitoring medication apparatus and method
GB9911388D0 (en) * 1999-05-18 1999-07-14 Glaxo Group Ltd Dispenser
SE516826C2 (en) * 1999-06-18 2002-03-05 Shl Medical Ab Breath-operated device for use with an inhaler includes a return mechanism for deactivating a canister to close when airflow drops below a certain threshold value
SE9902672D0 (en) * 1999-07-12 1999-07-12 Astra Ab Delivery device
US6615827B2 (en) 1999-09-08 2003-09-09 Sapphire Designs, Inc. Inhalation counter device
FR2799858B1 (en) 1999-10-19 2002-01-18 Valois Sa DOSAGE COUNTER AND FLUID PRODUCT DISPENSER INCORPORATING SUCH A COUNTER
JP2003513718A (en) 1999-11-10 2003-04-15 イノベーティブ・ディバイシィーズ・エルエルシー Inhalation actuator for use with a metered dose inhaler (MDI)
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
GB2360216A (en) 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
GB2360219A (en) * 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
GB0006525D0 (en) * 2000-03-18 2000-05-10 Astrazeneca Uk Ltd Inhaler
US6581590B1 (en) * 2000-03-21 2003-06-24 Iep Pharmaceutical Devices Inc. Inhalation actuated device
US6637432B2 (en) * 2000-05-09 2003-10-28 Iep Pharmaceutical Devices Inc. Inhalation actuated device
US20020000225A1 (en) * 2000-06-02 2002-01-03 Carlos Schuler Lockout mechanism for aerosol drug delivery devices
US6553988B1 (en) * 2000-06-09 2003-04-29 Norton Healthcare, Inc. Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber
TWI224512B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Reservoir pressure system for medicament inhaler
GB0016123D0 (en) * 2000-07-01 2000-08-23 Glaxo Group Ltd Valve for aerosol container
CA2415297A1 (en) 2000-07-15 2002-01-24 Glaxo Group Limited Medicament dispenser
PT1303326E (en) * 2000-07-24 2012-10-11 Clinical Designs Ltd Dispenser
US20020043262A1 (en) * 2000-08-22 2002-04-18 Alan Langford Spray device
FR2813214B1 (en) * 2000-08-29 2003-05-02 Valois Sa IMPROVED FLUID PRODUCT DISPENSING DEVICE
SE517228C2 (en) 2000-09-25 2002-05-14 Microdrug Ag Dry powder inhaler with respiratory activation
EP1320397B1 (en) 2000-09-29 2010-01-20 Pfizer Limited Medical Inhalation-Device
US6442234B1 (en) 2000-10-03 2002-08-27 Advanced Micro Devices, Inc. X-ray inspection of ball contacts and internal vias
GB0025749D0 (en) * 2000-10-20 2000-12-06 Glaxo Group Ltd Inhaler
GB0026646D0 (en) 2000-10-31 2000-12-13 Glaxo Group Ltd Medicament dispenser
USD455208S1 (en) * 2000-12-05 2002-04-02 Clinical Designs Limited Inhaler
DE10061723C2 (en) 2000-12-12 2003-01-16 Eckert Rosemarie Counter for counting metered deliveries of liquid, pasty or solid products as well as device for metered dispensing of such products
SE0100034D0 (en) 2001-01-04 2001-01-04 Astrazeneca Ab A delivery device
US20040079361A1 (en) * 2001-01-17 2004-04-29 Clayton Colin D. Medicinal aerosols
GB0101944D0 (en) * 2001-01-25 2001-03-07 Bacon Raymond J Dispenser
EP1357965B1 (en) * 2001-01-25 2014-09-24 Clinical Designs Limited Dispenser for medicament
GB2372541B (en) * 2001-02-23 2003-08-20 Bespak Plc Dosage counting devices
GB0108228D0 (en) 2001-04-02 2001-05-23 Glaxo Group Ltd Medicament dispenser
GB0109717D0 (en) * 2001-04-20 2001-06-13 Glaxo Group Ltd Medicament dispenser
AU2002322314B2 (en) * 2001-06-26 2006-08-17 Norton Healthcare, Ltd. An improved aerosol actuator
USD480474S1 (en) 2001-11-01 2003-10-07 Astrazeneca Ab Inhaler
US7322352B2 (en) * 2002-09-21 2008-01-29 Aventis Pharma Limited Inhaler
AU158576S (en) 2003-07-05 2006-08-22 Clinical Designs Ltd Inhaler

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CN1642592A (en) 2005-07-20

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