CA2500820A1 - Blood processing systems and methods with umbilicus-driven blood processing chambers - Google Patents

Blood processing systems and methods with umbilicus-driven blood processing chambers Download PDF

Info

Publication number
CA2500820A1
CA2500820A1 CA002500820A CA2500820A CA2500820A1 CA 2500820 A1 CA2500820 A1 CA 2500820A1 CA 002500820 A CA002500820 A CA 002500820A CA 2500820 A CA2500820 A CA 2500820A CA 2500820 A1 CA2500820 A1 CA 2500820A1
Authority
CA
Canada
Prior art keywords
frame
rotational axis
umbilicus
rotation
assembly according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002500820A
Other languages
French (fr)
Other versions
CA2500820C (en
Inventor
Sanjay V. Odak
Michael Kast
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fenwal Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2500820A1 publication Critical patent/CA2500820A1/en
Application granted granted Critical
Publication of CA2500820C publication Critical patent/CA2500820C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222—Details related to the interface between cassette and machine
    • A61M1/362227—Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36225—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with blood pumping means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362261—Constructional details of cassettes, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362263—Details of incorporated filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362265—Details of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362266—Means for adding solutions or substances to the blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/06—Control using electricity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0492—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with fluid conveying umbilicus between stationary and rotary centrifuge parts

Abstract

A blood processing assembly comprises a frame (70) rotatable about a rotational axis (82) and a blood processing chamber (18) carried by the frame (70) for rotation about the rotational axis(82). An umbilicus (100) has one end coupled to the blood processing chamber (18) along the rotational axis (82) and an opposite end held in a non-rotating position along the rotational axis (82). A mid region of the umbilicus (100) extends, at least in part, outside the rotational axis (82). The frame (70) carries at least one support channel (96, 98), which is sized and configured to engage the mid region of the umbilicus (100). The support channel (96, 98) includes a side edge (99, 101) that is sized and configured to self-load the mid region of the umbilicus (100) into the support channel (96, 98) in response to rotation of the frame (70) in a designated direction.

Claims (30)

1. A blood processing assembly comprising a frame rotatable about a rotational axis, a blood processing chamber carried by the frame for rotation about the rotational axis, an umbilicus having one end coupled to the blood processing chamber along the rotational axis and an opposite end held in a non-rotating position along the rotational axis, with a mid region of the umbilicus extending, at least in part, outside the rotational axis, and at least one support channel on the frame being sized and configured to engage the mid region of the umbilicus, the support channel including an edge that is sized and configured to self-load the mid region of the umbilicus into the support channel in response to rotation of the frame in a designated direction.
2. An assembly according to claim 1 wherein the frame is adapted to be rotated in a given direction during a blood separation procedure, and wherein the designated direction is opposite to the given direction.
3. An assembly according to claim 1 wherein the support channel is sized and configured to inhibit travel of the umbilicus in radial directions toward and away from the rotational axis.
4. An assembly according to claim 1 wherein the support channel imparts rotation to the mid portion in response to rotation of the frame about the rotational axis.
5. An assembly according to claim 4 wherein rotation of the umbilicus imparts rotation to the blood processing chamber.
6. An assembly according to claim 1 wherein the support channel includes a low friction material.
7. A blood processing assembly comprising a frame rotatable about a rotational axis, a blood processing chamber carried by the frame for rotation about the rotational axis, an umbilicus having one end coupled to the blood processing chamber along the rotational axis and an opposite end held in a non-rotating position along the rotational axis, with a mid region of the umbilicus extending, at least in part, outside the rotational axis, and first and second support channels spaced apart on the frame along the rotational axis, the first and second support channels being sized and configured to mutually engage. the mid region of the umbilicus, the first and second support channels being arranged in a reverse facing relationship to mutually engage the mid region regardless of direction of rotation of the frame.
8. An assembly according to claim 7 wherein at least one of the support channel is sized and configured to inhibit travel of the umbilicus in radial directions toward and away from the rotational axis.
9. An assembly according to claim 7 wherein at least one of the support channels imparts rotation to the mid portion in response to rotation of the frame about the rotational axis.
10. An assembly according to claim 9 wherein rotation of the umbilicus imparts rotation to the blood processing chamber.
11. An assembly according to claim 7 wherein at least one of the support channels includes a low friction material.
12. A blood processing assembly comprising a frame rotatable about a rotational axis, the frame having walls that define an open interior space through which the rotational axis passes, a drive mechanism coupled to the frame to rotate the frame about the rotational axis, a rotor carried by the frame within the open interior space for relative rotation about the rotational axis, a blood processing chamber secured to the rotor far rotation with the rotor about the rotational axis, an umbilicus having an end coupled to the blood processing chamber along the rotational axis, a mount aligned with the rotational axis outside, the frame for holding an opposite end of the umbilicus in a non-rotating and stationary position, with a mid region of the umbilicus being bowed outside the rotational axis, and first and second support channels spaced apart on the frame along the rotational axis, the first and second support channels being sized and configured to mutually engage the mid region of the umbilicus to impart rotation to the mid portion in response to rotation of the frame about the rotational axis, the first and second support channels being arranged in a reverse facing relationship to mutually engage the mid region regardless of direction of rotation of the frame.
13. An assembly according to claim 12 wherein at least one of the first and second support channels includes opposed side edges that lead inward toward the respective support channel to guide the mid region of the umbilicus into engagement with the respective channel in response to rotation of the frame and regardless of direction of rotation of the frame.
14. An assembly according to claim 12 wherein at least one of the first and second support channels, includes aside edge that is sized and configured to self-load the mid region of the umbilicus into the respective support channel in response to rotation of the frame in a designated direction.
15. An assembly according to claim 12 wherein the first and second a second support channels are sized and configured to inhibit travel of the umbilicus in radial directions toward and away from the rotational axis.
16. An assembly according to claim 12 wherein the first and second support channels are sized and configured to lead the opposite end of the umbilicus toward the mount.
17. An assembly according to claim 12.
wherein rotation of the umbilicus imparts rotation to the blood processing chamber secured to the rotor.
18. An assembly according to claim 12 wherein one of the support channels faces generally toward the frame and the other one of the support channels faces generally away from the frame.
19. An assembly according to claim 12 wherein the one support channel closest to the mount faces generally away from the frame and the other support channel farthest from the mount faces generally toward the frame.
20. An assembly according to claim 19 wherein the one support channel includes opposed side edges that lead inward toward the respective support channel to guide the mid region of the umbilicus into engagement with the respective channel in response to rotation of the frame and regardless of the direction of rotation of the frame.
21. An assembly according to claim 12 wherein at least one of the first and second support channels includes a side edge that is sized and configured to self-load the mid region of the umbilicus into the respective support channel in response to rotation of the frame in a designated direction.
22. An assembly according to claim 12 wherein the one support channel is sized and configured to lead the opposite end of the umbilicus toward the mount.
23. An assembly according to claim 12 wherein at least one of the first and second support channels includes a low friction material.
24. A blood processing assembly comprising a frame rotatable about a rotational axis, the frame having walls that define an open interior space through which the rotational axis passes, a drive mechanism coupled to the frame to rotate the frame about the rotational axis, a rotor carried by the frame within the open interior space for relative rotation about the rotational axis, a blood processing chamber secured to the rotor for rotation with the rotor about the rotational axis, an umbilicus having an end coupled to the blood processing chamber along the rotational axis, a mount aligned with the rotational axis outside the frame for holding an opposite end of the umbilicus in a non-rotating and stationary position, with a mid region of the umbilicus being bowed outside the rotational axis, and first and second support channels spaced apart on the frame along the rotational axis, the first and second support channels being sized and configured to mutually engage the mid region of the umbilicus to impart rotation to the mid portion in response to rotation of the frame about the rotational axis, at least one of the first and second support channels includes opposed side edges that lead inward toward the respective support channel to guide the mid region of the umbilicus into engagement with the respective channel in response to rotation of the frame and regardless of direction of rotation of the frame.
25. An assembly according to claim 24 wherein at least one of the side edges is sized and configured to self-load the mid region of the umbilicus into the respective support channel in response to rotation of the frame in a designated direction.
26. An assembly according to claim 24 wherein the first and second a second support channels are sized and configured to inhibit travel of the umbilicus in radial directions toward and away from the rotational axis.
27. An assembly according to claim 24 wherein the first and second support channels are sized and configured to lead the opposite end of the umbilicus toward the mount.
28. An assembly according to claim 24 wherein rotation of the umbilicus imparts rotation to the blood processing chamber secured to the rotor.
29. An assembly according to claim 24 wherein one of the support channels faces generally toward the frame and the other one of the support channels faces generally away from the frame.
30. An assembly according to claim 24 wherein at least one of the first and second support channels includes a low friction material.
CA2500820A 2002-10-24 2003-10-21 Blood processing systems and methods with umbilicus-driven blood processing chambers Expired - Lifetime CA2500820C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/279,779 US6860846B2 (en) 1999-09-03 2002-10-24 Blood processing systems and methods with umbilicus-driven blood processing chambers
US10/279,779 2002-10-24
PCT/US2003/033469 WO2004037427A1 (en) 2002-10-24 2003-10-21 Blood processing systems and methods with umbilicus-driven blood processing chambers

Publications (2)

Publication Number Publication Date
CA2500820A1 true CA2500820A1 (en) 2004-05-06
CA2500820C CA2500820C (en) 2011-05-03

Family

ID=32106805

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2500820A Expired - Lifetime CA2500820C (en) 2002-10-24 2003-10-21 Blood processing systems and methods with umbilicus-driven blood processing chambers

Country Status (10)

Country Link
US (1) US6860846B2 (en)
EP (1) EP1554047B1 (en)
JP (1) JP4531564B2 (en)
CN (1) CN1708358A (en)
AU (1) AU2003286579B2 (en)
BR (1) BR0315634B1 (en)
CA (1) CA2500820C (en)
DE (1) DE60327877D1 (en)
MX (1) MXPA05004351A (en)
WO (1) WO2004037427A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003230862A1 (en) 2002-04-11 2003-10-27 Deka Products Limited Partnership System and method for delivering a target volume of fluid
JP4871496B2 (en) * 2004-06-16 2012-02-08 テルモ株式会社 Blood component collection device
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP1848474B1 (en) 2005-02-07 2013-06-12 Hanuman LLC Platelet rich plasma concentrate apparatus and method
ES2426941T3 (en) 2005-02-07 2013-10-25 Hanuman Llc Apparatus and procedure of platelet rich plasma concentrates
JP4607803B2 (en) * 2006-03-30 2011-01-05 テルモ株式会社 Blood component collection device
US8491184B2 (en) 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US8708950B2 (en) 2010-07-07 2014-04-29 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US10195330B2 (en) 2008-01-23 2019-02-05 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9078971B2 (en) 2008-01-23 2015-07-14 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US10201647B2 (en) 2008-01-23 2019-02-12 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9248225B2 (en) 2008-01-23 2016-02-02 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US11833281B2 (en) 2008-01-23 2023-12-05 Deka Products Limited Partnership Pump cassette and methods for use in medical treatment system using a plurality of fluid lines
WO2009111338A1 (en) 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8257239B2 (en) * 2010-06-15 2012-09-04 Fenwal, Inc. Umbilicus for use in an umbilicus-driven fluid processing
WO2013067359A2 (en) 2011-11-04 2013-05-10 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
JP6161065B2 (en) * 2013-07-02 2017-07-12 国立研究開発法人産業技術総合研究所 Blood information measuring device and measuring method
EP3142796A4 (en) 2014-05-16 2017-12-20 Qvella Corporation Apparatus, system and method for performing automated centrifugal separation
EP3698826A1 (en) 2014-06-05 2020-08-26 DEKA Products Limited Partnership System for calculating a change in fluid volume in a pumping chamber
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US10022265B2 (en) * 2015-04-01 2018-07-17 Zoll Circulation, Inc. Working fluid cassette with hinged plenum or enclosure for interfacing heat exchanger with intravascular temperature management catheter
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
WO2016205511A1 (en) * 2015-06-19 2016-12-22 Mallinckrodt Hospital Products IP Limited Devices, methods, and systems for priming, separating, and collecting blood components
US10413902B2 (en) 2015-07-17 2019-09-17 Stat-Diagnostica & Innovation, S.L. Apparatus for sample separation and collection
BR112020019993A2 (en) 2018-03-30 2021-01-26 Deka Products Limited Partnership liquid pumping cassettes and associated pressure distribution manifold and related methods

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1647292A (en) 1922-01-05 1927-11-01 Hill Hugh Suction sweeper
US3666170A (en) 1969-05-07 1972-05-30 Glacier Metal Co Ltd Centrifugal separator
US3785549A (en) 1972-07-31 1974-01-15 Haemonetics Corp Centrifuge chuck for disposable, snap-in centrifuge rotor
US4734089A (en) 1976-05-14 1988-03-29 Baxter Travenol Laboratories, Inc. Centrifugal blood processing system
US4091989A (en) 1977-01-04 1978-05-30 Schlutz Charles A Continuous flow fractionation and separation device and method
US4120448A (en) 1977-06-08 1978-10-17 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing apparatus with automatically positioned collection port
US4109854A (en) 1977-06-13 1978-08-29 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with outer enclosure
SE408859B (en) * 1977-08-03 1979-07-16 Separex Sa DEVICE FOR THE OCCUPATION OF UNLIMITED CORRECT RELATIVE ROTATION BETWEEN THE ENDS OF A WIRED ELEMENT
US5571068A (en) 1977-08-12 1996-11-05 Baxter International Inc. Centrifuge assembly
US4164318A (en) 1977-10-12 1979-08-14 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus with reduced-load tubing
US4146172A (en) 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
SE412528B (en) 1978-07-25 1980-03-10 Separex Sa CENTRIFUGROTOR AND COLLABLE SEPARATION CONTAINER
JPS56166957A (en) * 1980-05-26 1981-12-22 Asahi Chem Ind Co Ltd Apparatus for communicating fluid
US4389206A (en) 1980-10-09 1983-06-21 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus and rotatable processing bowl apparatus
US4439178A (en) * 1982-12-30 1984-03-27 International Business Machines Corporation Sealless centrifuge processing channel and tube system
US4708712A (en) 1986-03-28 1987-11-24 Cobe Laboratories, Inc. Continuous-loop centrifugal separator
US5370802A (en) 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US4834890A (en) 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
SE458342B (en) 1987-07-06 1989-03-20 Alfa Laval Ab CENTRIFUGAL SEPARATOR INCLUDING A ROTOR WITH A SEPARATION CHAMBER CONSISTING OF TWO DEPARTMENTS
US5078671A (en) 1988-10-07 1992-01-07 Baxter International Inc. Centrifugal fluid processing system and method
US5549834A (en) 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5833866A (en) 1991-12-23 1998-11-10 Baxter International Inc. Blood collection systems and methods which derive instantaneous blood component yield information during blood processing
AU652888B2 (en) 1991-12-23 1994-09-08 Baxter International Inc. Centrifugal processing system with direct access drawer
DE4220232A1 (en) 1992-06-20 1993-12-23 Fresenius Ag centrifuge
DE4227695C1 (en) 1992-08-21 1993-10-07 Fresenius Ag Centrifuge to separate blood into its components
US5308309A (en) 1992-12-23 1994-05-03 Therakos, Inc. Securing system for centrifuge chamber
CH687505A5 (en) 1993-01-29 1996-12-31 Elp Rochat Centrifugal separator for fluids.
WO1994025086A1 (en) 1993-04-27 1994-11-10 Haemonetics Corporation Apheresis apparatus and method
US5525218A (en) * 1993-10-29 1996-06-11 Baxter International Inc. Centrifuge with separable bowl and spool elements providing access to the separation chamber
WO1995017218A1 (en) 1993-12-22 1995-06-29 Baxter International Inc. Self-priming drip chamber with enhanced visibility
US5462416A (en) 1993-12-22 1995-10-31 Baxter International Inc. Peristaltic pump tube cassette for blood processing systems
US5529567A (en) 1994-07-01 1996-06-25 Baxter International Inc. Blood processing system having spill sensor with fail-safe circuit
US5651766A (en) 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US5581687A (en) 1994-11-10 1996-12-03 Baxter International Inc. Interactive control systems for medical processing devices
US6053856A (en) 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
BR9608031A (en) 1995-04-18 1999-11-30 Cobe Lab Particle separation apparatus and process
US5720716A (en) 1995-06-07 1998-02-24 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5837150A (en) 1995-06-07 1998-11-17 Cobe Laboratories, Inc. Extracorporeal blood processing methods
US5750025A (en) 1995-06-07 1998-05-12 Cobe Laboratories, Inc. Disposable for an apheresis system with a contoured support
US5658231A (en) 1995-09-21 1997-08-19 Haemonetics Corporation Mechanism for securing a separation bowl to a mechanical chuck
US5769811A (en) 1995-10-31 1998-06-23 Haemonetics Corporation Blood-processing machine system
US5643193A (en) 1995-12-13 1997-07-01 Haemonetics Corporation Apparatus for collection washing and reinfusion of shed blood
US5792038A (en) 1996-05-15 1998-08-11 Cobe Laboratories, Inc. Centrifugal separation device for providing a substantially coriolis-free pathway
WO1998022165A1 (en) 1996-11-22 1998-05-28 Therakos, Inc. Integrated cassette for controlling fluid having an integral filter
DE19706997C2 (en) 1997-02-22 1999-08-05 Sigma Laborzentrifugen Gmbh Laboratory centrifuge
US5964690A (en) 1997-03-19 1999-10-12 Medtronic, Inc. Mechanism for fixing a blood centrifuge bowl to a rotating spindle
WO1998043720A1 (en) 1997-04-03 1998-10-08 Baxter International Inc. Interface detection and control systems and methods
US5989177A (en) 1997-04-11 1999-11-23 Baxter International Inc. Umbilicus gimbal with bearing retainer
KR100656124B1 (en) * 1997-04-24 2006-12-20 카네카 코포레이션 Impact-resistant thermoplastic resin composition
WO1998048938A1 (en) 1997-04-25 1998-11-05 Washington State University Research Foundation Semi-continuous, small volume centrifugal blood separator
US6027657A (en) 1997-07-01 2000-02-22 Baxter International Inc. Systems and methods for collecting diluted mononuclear cells
US5980760A (en) 1997-07-01 1999-11-09 Baxter International Inc. System and methods for harvesting mononuclear cells by recirculation of packed red blood cells
US7011761B2 (en) * 1999-09-03 2006-03-14 Baxter International Inc. Red blood cell processing systems and methods which control red blood cell hematocrit
US20020094927A1 (en) * 1999-09-03 2002-07-18 Baxter International Inc. Blood separation systems and methods with umbilicus-driven blood separation chambers

Also Published As

Publication number Publication date
US6860846B2 (en) 2005-03-01
MXPA05004351A (en) 2005-08-02
EP1554047A1 (en) 2005-07-20
AU2003286579A1 (en) 2004-05-13
EP1554047A4 (en) 2007-06-13
AU2003286579B2 (en) 2008-07-17
JP4531564B2 (en) 2010-08-25
JP2006503652A (en) 2006-02-02
CN1708358A (en) 2005-12-14
CA2500820C (en) 2011-05-03
EP1554047B1 (en) 2009-06-03
BR0315634B1 (en) 2014-01-28
US20040082458A1 (en) 2004-04-29
WO2004037427A1 (en) 2004-05-06
BR0315634A (en) 2005-08-23
DE60327877D1 (en) 2009-07-16

Similar Documents

Publication Publication Date Title
CA2500820A1 (en) Blood processing systems and methods with umbilicus-driven blood processing chambers
JP4875321B2 (en) Ball screw mechanism
CN110529526B (en) Actuator for a brake device
CN1192953A (en) Cylinder apparatus
CA2996255C (en) Anti-spin dust seal for cone and gyratory crushers
JP2009527362A (en) Spinning device and shaping device
JP2000170885A (en) Pulley
US20110198033A1 (en) Shutter device and vacuum processing apparatus
WO2018049137A1 (en) Spin windows with integrated cameras
US10434585B2 (en) Saw blade positioning mechanism for annular sawing machine
WO1998044506A3 (en) Cassette having at least one axially movable reel and having blocking means for blocking an axial movement of the reel
KR101860209B1 (en) Grip for pipe forming apparatus screw-type
EP1696797A2 (en) Medical diagnostic apparatus comprising a drive system for positioning a radiation source facing a radiation detector
JP2007302231A (en) Tilting and telescopic steering apparatus
US20040098735A1 (en) Disk loading apparatus for a disk drive
KR101847952B1 (en) Clear View Screen Apparatus for Ship
CN214194260U (en) Movement structure of gate and gate
AU2016102327A4 (en) Saw Blade Positioning Mechanism for Annular Sawing Machine
JP4167546B2 (en) Outer rotor type brushless motor for automatic door
JP4509745B2 (en) blind
JPH10170806A (en) Lens barrel
KR20200029420A (en) Actuator for brake device
JPH04276101A (en) Axial piston machine
JP2014130266A (en) Rotor lock mechanism and rotating plate driving apparatus
CN115609477A (en) Elastic rotation flat-floating clamping mechanism

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20231023