CA2500928A1 - Device with an expandable portion for drug release - Google Patents
Device with an expandable portion for drug release Download PDFInfo
- Publication number
- CA2500928A1 CA2500928A1 CA002500928A CA2500928A CA2500928A1 CA 2500928 A1 CA2500928 A1 CA 2500928A1 CA 002500928 A CA002500928 A CA 002500928A CA 2500928 A CA2500928 A CA 2500928A CA 2500928 A1 CA2500928 A1 CA 2500928A1
- Authority
- CA
- Canada
- Prior art keywords
- voids
- expandable portion
- drug
- medical device
- drug release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
Abstract
The present invention relates to a medical device and a method of delivering a drug to a target circulation or tissue. The medical device has an expandable portion (16) which is fabricated from a porous elastomeric material with a plurality of voids (18)therein. The voids (18) are loaded with drugs (22) in various formulations. Upon inflation of the expandable portion (16), the overall diameter (26) increases, the wall (19) thickness (28) decreases and, consequently, the voids (18) are stretched to cause the drug to be expelled from the voids (18) and into the bodily lumen or tissue adjacent to the medical device. The voids (18) include any open volume within the expandable portion (16) capable of containing the drug (22).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/283,684 US7048714B2 (en) | 2002-10-30 | 2002-10-30 | Drug eluting medical device with an expandable portion for drug release |
US10/283,684 | 2002-10-30 | ||
PCT/IB2003/004785 WO2004039445A1 (en) | 2002-10-30 | 2003-10-28 | Device with an expandable portion for drug release |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2500928A1 true CA2500928A1 (en) | 2004-05-13 |
CA2500928C CA2500928C (en) | 2009-04-07 |
Family
ID=32174713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002500928A Expired - Fee Related CA2500928C (en) | 2002-10-30 | 2003-10-28 | Device with an expandable portion for drug release |
Country Status (11)
Country | Link |
---|---|
US (1) | US7048714B2 (en) |
EP (1) | EP1562669B1 (en) |
JP (1) | JP4436761B2 (en) |
CN (1) | CN1708327A (en) |
AT (1) | ATE416816T1 (en) |
AU (1) | AU2003274471C1 (en) |
CA (1) | CA2500928C (en) |
DE (1) | DE60325267D1 (en) |
ES (1) | ES2314241T3 (en) |
IL (1) | IL167645A (en) |
WO (1) | WO2004039445A1 (en) |
Families Citing this family (90)
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US7655000B2 (en) * | 2003-09-26 | 2010-02-02 | Tyco Healthcare Group Lp | Urology catheter |
US8431145B2 (en) * | 2004-03-19 | 2013-04-30 | Abbott Laboratories | Multiple drug delivery from a balloon and a prosthesis |
US20070027523A1 (en) * | 2004-03-19 | 2007-02-01 | Toner John L | Method of treating vascular disease at a bifurcated vessel using coated balloon |
ATE534424T1 (en) * | 2004-03-19 | 2011-12-15 | Abbott Lab | MULTIPLE MEDICINAL DELIVERY FROM A BALLOON AND A PROSTHESIS |
US20100030183A1 (en) * | 2004-03-19 | 2010-02-04 | Toner John L | Method of treating vascular disease at a bifurcated vessel using a coated balloon |
US20060079727A1 (en) * | 2004-09-03 | 2006-04-13 | Rubicor Medical, Inc. | Short term post surgical cavity treatment devices and methods |
US8771257B2 (en) * | 2004-10-15 | 2014-07-08 | Boston Scientific Scimed, Inc. | Drug delivery sheath |
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US8048028B2 (en) * | 2005-02-17 | 2011-11-01 | Boston Scientific Scimed, Inc. | Reinforced medical balloon |
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US20070067882A1 (en) * | 2005-09-21 | 2007-03-22 | Liliana Atanasoska | Internal medical devices having polyelectrolyte-containing extruded regions |
US20070100368A1 (en) * | 2005-10-31 | 2007-05-03 | Quijano Rodolfo C | Intragastric space filler |
US20080243068A1 (en) * | 2005-12-29 | 2008-10-02 | Kamal Ramzipoor | Methods and apparatus for treatment of venous insufficiency |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US7967820B2 (en) | 2006-02-07 | 2011-06-28 | P Tech, Llc. | Methods and devices for trauma welding |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
US20080069855A1 (en) * | 2006-08-21 | 2008-03-20 | Bonutti Peter M | Method of inhibiting the formation of adhesions and scar tissue and reducing blood loss |
US20080085293A1 (en) * | 2006-08-22 | 2008-04-10 | Jenchen Yang | Drug eluting stent and therapeutic methods using c-Jun N-terminal kinase inhibitor |
US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
US8414909B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US20080140002A1 (en) * | 2006-12-06 | 2008-06-12 | Kamal Ramzipoor | System for delivery of biologically active substances with actuating three dimensional surface |
US20100185146A1 (en) * | 2006-12-06 | 2010-07-22 | Laura N. Dietch | Drug delivery systems |
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KR20120106880A (en) | 2007-01-21 | 2012-09-26 | 헤모텍 아게 | Medical product for treating stenosis of body passages and for preventing threatening restenosis |
US8226602B2 (en) * | 2007-03-30 | 2012-07-24 | Reshape Medical, Inc. | Intragastric balloon system and therapeutic processes and products |
JP2008305262A (en) * | 2007-06-08 | 2008-12-18 | Konica Minolta Business Technologies Inc | Printer introduction method in server and thin client environment |
US8142469B2 (en) * | 2007-06-25 | 2012-03-27 | Reshape Medical, Inc. | Gastric space filler device, delivery system, and related methods |
US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
WO2009036135A1 (en) * | 2007-09-12 | 2009-03-19 | Cook Incorporated | Balloon catheter for delivering a therapeutic agent |
US20110137245A1 (en) * | 2007-09-12 | 2011-06-09 | Cook Medical Technologies Llc | Balloon catheter with embedded rod |
CN101918050A (en) * | 2007-10-10 | 2010-12-15 | Miv治疗有限公司 | Lipid coatings for implantable medical devices |
US8070720B2 (en) * | 2008-01-11 | 2011-12-06 | Medtronic Vascular, Inc | Methods for incorporating a drug into an elastomeric medical device |
WO2009096822A1 (en) | 2008-01-30 | 2009-08-06 | Micromuscle Ab | Drug delivery devices and methods and applications thereof |
EP2262566A1 (en) * | 2008-03-06 | 2010-12-22 | Boston Scientific Scimed, Inc. | Balloon catheter devices with folded balloons |
EP2106820A1 (en) * | 2008-03-31 | 2009-10-07 | Torsten Heilmann | Expansible biocompatible coats comprising a biologically active substance |
US8034022B2 (en) | 2008-04-08 | 2011-10-11 | Cook Medical Technologies Llc | Weeping balloon catheter |
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US8226603B2 (en) | 2008-09-25 | 2012-07-24 | Abbott Cardiovascular Systems Inc. | Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery |
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US8049061B2 (en) | 2008-09-25 | 2011-11-01 | Abbott Cardiovascular Systems, Inc. | Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery |
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US9174031B2 (en) * | 2009-03-13 | 2015-11-03 | Reshape Medical, Inc. | Device and method for deflation and removal of implantable and inflatable devices |
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EP2453938B1 (en) | 2009-07-17 | 2015-08-19 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
WO2011011629A2 (en) | 2009-07-22 | 2011-01-27 | Reshape Medical, Inc. | Retrieval mechanisms for implantable medical devices |
WO2011011743A2 (en) | 2009-07-23 | 2011-01-27 | Reshape Medical, Inc. | Deflation and removal of implantable medical devices |
US9604038B2 (en) | 2009-07-23 | 2017-03-28 | Reshape Medical, Inc. | Inflation and deflation mechanisms for inflatable medical devices |
EP2480279A4 (en) | 2009-09-24 | 2017-11-15 | Reshape Medical, Inc. | Normalization and stabilization of balloon surfaces for deflation |
US8480620B2 (en) * | 2009-12-11 | 2013-07-09 | Abbott Cardiovascular Systems Inc. | Coatings with tunable solubility profile for drug-coated balloon |
US8951595B2 (en) * | 2009-12-11 | 2015-02-10 | Abbott Cardiovascular Systems Inc. | Coatings with tunable molecular architecture for drug-coated balloon |
US20110144577A1 (en) * | 2009-12-11 | 2011-06-16 | John Stankus | Hydrophilic coatings with tunable composition for drug coated balloon |
JP5553908B2 (en) * | 2009-12-30 | 2014-07-23 | カリバー セラピューティクス インコーポレイテッド | Balloon catheter system for delivering dry drug delivery vesicles to a body vessel |
US9622896B2 (en) | 2010-02-08 | 2017-04-18 | Reshape Medical, Inc. | Enhanced aspiration processes and mechanisms for instragastric devices |
EP2533846B1 (en) | 2010-02-08 | 2018-08-22 | ReShape Medical LLC | Materials and methods for improved intragastric balloon devices |
WO2011106637A1 (en) | 2010-02-25 | 2011-09-01 | Reshape Medical, Inc. | Improved and enhanced explant processes and mechanisms for intragastric devices |
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CN108371746B (en) * | 2015-09-18 | 2021-01-05 | 宋殿芳 | Gynaecology's anti-drop's of external use medicine device of giving medicine to poor free of charge |
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US11744732B2 (en) * | 2017-10-19 | 2023-09-05 | Amo Development, Llc | Medication-coated patient interface device for ophthalmic laser surgery |
JP2023512663A (en) | 2020-01-24 | 2023-03-28 | パッチクランプ メドテック, インコーポレイテッド | Tissue repair and sealing device with removable graft and fastener assembly and method for using same |
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-
2002
- 2002-10-30 US US10/283,684 patent/US7048714B2/en not_active Expired - Lifetime
-
2003
- 2003-10-28 DE DE60325267T patent/DE60325267D1/en not_active Expired - Lifetime
- 2003-10-28 CN CNA2003801023087A patent/CN1708327A/en active Pending
- 2003-10-28 EP EP03758446A patent/EP1562669B1/en not_active Expired - Lifetime
- 2003-10-28 JP JP2004547911A patent/JP4436761B2/en not_active Expired - Fee Related
- 2003-10-28 AT AT03758446T patent/ATE416816T1/en not_active IP Right Cessation
- 2003-10-28 CA CA002500928A patent/CA2500928C/en not_active Expired - Fee Related
- 2003-10-28 WO PCT/IB2003/004785 patent/WO2004039445A1/en active Application Filing
- 2003-10-28 AU AU2003274471A patent/AU2003274471C1/en not_active Ceased
- 2003-10-28 ES ES03758446T patent/ES2314241T3/en not_active Expired - Lifetime
-
2005
- 2005-03-24 IL IL167645A patent/IL167645A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US7048714B2 (en) | 2006-05-23 |
ES2314241T3 (en) | 2009-03-16 |
EP1562669A4 (en) | 2006-06-21 |
AU2003274471C1 (en) | 2008-10-23 |
JP4436761B2 (en) | 2010-03-24 |
DE60325267D1 (en) | 2009-01-22 |
JP2006504463A (en) | 2006-02-09 |
EP1562669B1 (en) | 2008-12-10 |
IL167645A (en) | 2012-02-29 |
WO2004039445A1 (en) | 2004-05-13 |
US20040087902A1 (en) | 2004-05-06 |
AU2003274471A1 (en) | 2004-05-25 |
AU2003274471B2 (en) | 2008-02-28 |
CA2500928C (en) | 2009-04-07 |
ATE416816T1 (en) | 2008-12-15 |
EP1562669A1 (en) | 2005-08-17 |
CN1708327A (en) | 2005-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20201028 |