CA2518366A1 - Medical device for manipulation of a medical implant - Google Patents
Medical device for manipulation of a medical implant Download PDFInfo
- Publication number
- CA2518366A1 CA2518366A1 CA002518366A CA2518366A CA2518366A1 CA 2518366 A1 CA2518366 A1 CA 2518366A1 CA 002518366 A CA002518366 A CA 002518366A CA 2518366 A CA2518366 A CA 2518366A CA 2518366 A1 CA2518366 A1 CA 2518366A1
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- Canada
- Prior art keywords
- expandable component
- sleeve
- medical device
- medical
- expandable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12122—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00601—Implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00623—Introducing or retrieving devices therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/011—Instruments for their placement or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
Abstract
This invention relates to medical devices for manipulating medical implants such as, for example, stents, distal protection filters, and septal occluders in a patient's body, and the methods of use thereof. Generally, a medical device of the invention includes a sleeve and an expandable component joined to the sleeve which transitions between a collapsed configuration and a deployed configuration for capturing a medical implant in a patient's body.
Description
MEDICAL DEVICE FOR MANIPULATION OF A MEDICAL IMPLANT
FIELD ~~" ~I'Il'~l~i'~T°lI°I~1'~T
[OOOg] This invention generally relates to a cardiovascular medical device.
fore particularly, this invention relates to a medical device for manipulating a medical implant in the cardiovascular system of a patient and methods of use of such a medical device.
EACY~CROUND ~F THE INVENTION
FIELD ~~" ~I'Il'~l~i'~T°lI°I~1'~T
[OOOg] This invention generally relates to a cardiovascular medical device.
fore particularly, this invention relates to a medical device for manipulating a medical implant in the cardiovascular system of a patient and methods of use of such a medical device.
EACY~CROUND ~F THE INVENTION
[0002] Ie4edical implants have wide-spread use in percutaneous vascular and cardiac surgery.
These implants include, in particular, distal protection filter devices for the capture of thrombi in major veins such as the lower caval vein, occlusion devices for permanent or temporary obturation of a vessel lumen or permanent occlusion of defects in cardiac walls such as an atrial 1o septal defect (ASD), a patent ductus arteriosus (PDA), or other cardiovascular defects such as, patent foramen ovate (PFO) and left atrial appendage (LAA).
These implants include, in particular, distal protection filter devices for the capture of thrombi in major veins such as the lower caval vein, occlusion devices for permanent or temporary obturation of a vessel lumen or permanent occlusion of defects in cardiac walls such as an atrial 1o septal defect (ASD), a patent ductus arteriosus (PDA), or other cardiovascular defects such as, patent foramen ovate (PFO) and left atrial appendage (LAA).
[0003] Cardiac wall septal defects are usually congenital in nature leading to abnormal openings, holes or shunts between the chambers of the heart or the great blood vessels, causing abnormal shunting of blood through the opening. Such defects may result, for example, from the 15 incomplete formation of the septum, or wall, between cardiac chambers during fetal life when the heart develops from a folded tube into a four chambered, two unit system.
These deformities can result in significant health risks such as, high pulmonary arterial pressures and fatal heart failure, if not corrected.
These deformities can result in significant health risks such as, high pulmonary arterial pressures and fatal heart failure, if not corrected.
[0004] Initially, atrial septal defects were corrected by open heart surgery.
However, in 20 order to avoid the morbidity and mortality associated with open heart surgery, a variety of transcatheter closure techniques have been attempted in patients. In such techniques, a medical implant such as an occluding device, is delivered percutaneously through an intravascular catheter into a patient. Once the occluding device is positioned adjacent the defect, it is attached to the wall adjacent the septum in a manner which permits it to effectively bloclc the passage of 25 blood through the defect. One such medical implant is a septet occluder which is inserted percutaneously via a catheter into a chamber of the heart to occlude a septet defect in a patient.
A septet occluder is typically adapted very closely to the shape and size of the defect which is to _2_ be closed and is positioned very precisely upon implantation into the patient's heart. I~owever, in the event that the septal occluder is dislodged from its intended location, or misaligned with the defect, it is often difficult to retrieve the septal occluder due to its shape or sire.
Fua-thermore, the process of retrieving the septal occluder often causes damage to the surrounding vasculature.
However, in 20 order to avoid the morbidity and mortality associated with open heart surgery, a variety of transcatheter closure techniques have been attempted in patients. In such techniques, a medical implant such as an occluding device, is delivered percutaneously through an intravascular catheter into a patient. Once the occluding device is positioned adjacent the defect, it is attached to the wall adjacent the septum in a manner which permits it to effectively bloclc the passage of 25 blood through the defect. One such medical implant is a septet occluder which is inserted percutaneously via a catheter into a chamber of the heart to occlude a septet defect in a patient.
A septet occluder is typically adapted very closely to the shape and size of the defect which is to _2_ be closed and is positioned very precisely upon implantation into the patient's heart. I~owever, in the event that the septal occluder is dislodged from its intended location, or misaligned with the defect, it is often difficult to retrieve the septal occluder due to its shape or sire.
Fua-thermore, the process of retrieving the septal occluder often causes damage to the surrounding vasculature.
[0005] In addition to the use of medical implants for the treatment of septal defects, medical implants are also used to capture embolic debris caused by medical procedures that blood vessels stenosed or occluded in a patient caused by the deposit of plaque or other material on the walls of the blood vessels. Angioplasty, for example, is a widely known medical l0 procedure wherein a dilating device, such as an inflatable balloon, is introduced into the occluded region of the vessel. The balloon is inflated, dilating the occlusion and thereby increasing intraluminal diameter. Plaque material may be inadvertently dislodged during angioplasty. This material is free to travel downstream, possibly lodging within another portion of the blood vessel that may supply a vital organ thereby causing damage to the organ by 15 obstructing blood flow to the organ.
[0006] Medical implants such as distal protection filters are typically introduced into the desired blood vessel for capturing embolic debris dislodged during angioplasty. ~ne of the problems associated with the removal of a medical implant such as a distal protection filter from a patient's body is that the retrieval process results in the collapse of the distal protection filter 2o causing egress of particulate embolic matter back into the bloodstream. In the case of cerebral angioplasty, for example, emboli dislodged during the retrieval of a distal protection filter from a patient's body may travel to the brain, possibly causing a stroke, which can lead to permanent neurological injuries or even the death of the patient. Therefore, while distal protection filters are useful for trapping embolic debris that is dislodged or generated during a medical procedure, 25 such as angioplasty, the egress of embolic debris trapped in a distal protection filter back into the bloodstream of a patient while the distal protection filter is being removed from the patient's body remains a problem.
~~JMM~1~.~1 ~F T~iE III~TS~lE~dT~~I~T
~~JMM~1~.~1 ~F T~iE III~TS~lE~dT~~I~T
[0007] The invention disclosed herein relates to medical devices and the methods of use 3o of the medical devices for manipulating medical implants in patients. The medical devices of the invention result in a significant reduction in or prevention of problems and risks associated with the recovery or delivery of medical implants in patients such as, for example, escape of embolic debris from a distal protection filter as it is being removed from a patient or damaging of blood vessels during the delivery or retrieval of a septal occluder from a patient.
[~00~] ~ medical device according to the invention can be used to capture a medical implant for retrieval or delivery into a patient9 s body.
[000] In one aspect, the invention is directed to a medical device including a sleeve and an expandable component. The sleeve includes a lumen, a distal end and a proximal end and at least a portion of the expandable component is joined to the sleeve. The expandable component transitions between a collapsed state when the expandable component is enclosed by the sleeve, 1o and a deployed state when a portion of the expandable component is extended beyond the distal end of the sleeve. The expandable component is sized and shaped for manipulating a medical implant in a patient's body. For example, in one embodiment, manipulating includes capturing a medical implant for recovery from or delivering of the medical implant inside a patient's body.
[0010] In one embodiment, the medical device of the invention further includes an elongate 15 member. The elongate member includes a distal end and a proximal end and at least a portion of the elongate member is slideably moveable within the lumen of the sleeve. In one embodiment, at least a portion of the expandable component is joined to the elongate member. In a particular embodiment, at least a portion of the expandable component is joined to the distal end of the elongate member.
20 [0011] In various embodiments of the foregoing aspect of the invention, the expandable component of the medical device is joined to the distal end of the sleeve.
[0012] The expandable component is deployed by relative sliding motion of the sleeve and the expandable component. In one embodiment, the expandable component is reciprocatably moveable relative to the sleeve, wherein the sleeve is stationary. In another embodiment, the 25 sleeve is reciprocatably moveable relative to the expandable component, wherein the expandable component is stationary. The expandable component may also be deployed by relative sliding motion of the elongate member within the lumen of the sleeve relative to the sleeve.
[001] In one embodiment, the expandable component has a conical shape in the deployed state. The expandable component may be sized and shaped to manipulate a septal occluder. 'The 3o expandable component may also be sized and shaped to manipulate a distal protection filter.
[0014] In another aspect, the invention relates to methods for manipulating a medical implant in a patient's body using the aforementioned medical devices of the invention.
One method of the invention includes providing a medical device of the invention including a sleeve with a lumen, a distal end and a proximal end and an expandable component, where at least a portion of the distal portion of the expandable component is joined to the sleeve and the expandable comp~nent transitions between a c~llapsed state when the expandable c~mponent is encl~sed by the sleeve and a deployed state when a portion of the expandable component is extended beyond the distal end of the sleeve, the expandable component being sued and shaped for manipulating a, medical implant in a patient's body.
to [001] Another method of the invention includes providing the medical device that fiuther includes an elongate member that is slideably moveable within the lumen of the sleeve.
[0016] In one embodiment, manipulating a medical implant using a method according to the invention includes capturing a medical implant for delivery inside a patient's body using the medical device of the invention. In another embodiment, manipulating a medical implant using 15 the method according to the invention includes capturing a medical implant for retrieval from a patient's body.
[0017] In other aspects, the invention relates to a medical device for capturing a medical implant in a patient's body including a sleeve means, an expandable means, and means for deploying the expandable means beyond the sleeve means. At least a portion of the expandable 2o means is joined to the sleeve means and the expandable means transitions between a collapsed state when the expandable means is enclosed by the sleeve means and a deployed state when a portion of the expandable means is extended beyond the sleeve means, the expandable means being sized and shaped for capturing the medical implant in the patient's body.
[0018] In all embodiments of the foregoing aspects of the invention, the medical implant to be 25 captured can be a septal occluder, a stmt or a distal protection filter.
[0019] In all the foregoing aspects of the invention, the expandable component can be fabricated from several materials and can assume many configurations. Suitable materials include any material that is flexible, collapsible and atraumatic. In one embodiment, the expandable component lncludes a mesh that is cylindrical. In another embodiment, the 3o expandable component includes braided material. The expandable component can assume many configurations such as a braid or an elastomeric tube. The braid configuration can include multiple braids or a partial braid.
[0020] The directional terms distal and proximal require a point of reference.
The term "distal" refers to a direction that points away from inn operator of a~
medical device in accordance with the invention and into the patient's body. The term 'dproximal" refers to ~ direction that points toward an operator of the medical device in accordance with the invention and away from the patient's body.
[002] These and other objects, along with advantages and features of the present invention herein disclosed, will become apparent through reference to the following description, the accompanying drawings, and the claims. Furthermore, it is to be understood that the features of the various embodiments described herein are not mutually exclusive and can exist in various combinations and permutations.
BRIEF DESCRIPTION OF THE DRAWINGS
[0022] In the drawings, like reference characters generally refer to corresponding parts throughout the different views. The drawings are not necessarily to scale9 emphasis instead being placed on illuminating the principles and eon cepts of the invention.
[002] FIG. 1A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including the expandable component in a collapsed configuration;
[002] FIG. 1B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 1A including the expandable component in a partially-to deployed configuration;
[0025] FIG. 1 C illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 1A including the expandable component in a substantially-deployed configuration;
[0026] FIG. 1D illustrates a partially-sectioned schematic view of an embodiment of the 15 medical device illustrated in FIG. 1 A including the expandable component in a fully-deployed configuration;
[0027] FIG. 2A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including an expandable component with an open proximal section;
2o [0028] FIG. 2B illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a cylindrical expandable component with open distal and proximal portions;
[0029] FIG. 2C illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a funnel-shaped expandable component;
25 [000] FIG. 3A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including an elongate member;
[OO~I] FIG. 313 illustrates s a partially-sectioned schematic view of an embodiment of the medical devise illustrated in FIG. 3A in eluding the expandable component in a substantially-deployed configuration for capturing a medical implant;
_7_ [0032] FIG. 4A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a lumen extending substantially through the entire length of the elongate member of the medical device;
[0033] FIG 4-B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 4~A in eluding the expandable component in a substantially-deployed configuration for capturing a medical implant;
[0034] FIG. 5A illustrates a schematic side-view of an embodiment of the expandable component of a medical device in accordance with the invention in a deployed configuration;
[003] FIG. 5B illustrates a schematic end-view of the deployed configuration of an to embodiment of the expandable component of the medical device illustrated in FIG. 5A;
[0036] FIG. 5C illustrates a schematic side-view of an embodiment of the expandable component illustrated in FIG. 5A in a collapsed configuration;
[0037] FIG. 6 is a cross-sectional view of the medical device of FIG. 4A
through 6-6.
[0038] FIG. 7A illustrates a partially-sectioned schematic view of an embodiment of the 15 medical device illustrated in FIG. 5A including a guide wire and a medical implant with a lumen;
[0039] FIG. 7B illustrates a partially-sectioned schematic view of the medical device illustrated in FIG. 7A, where the guide wire is extended substantially through the entire length of the medical device and the medical implant and beyond the distal end of the medical implant;
[0040] FIG. 7C illustrates a partially-sectioned schematic view of the medical device 2o illustrated in FIG. 7A including the expandable component capturing the medical implant;
[0041] FIG. 8A illustrates a schematic view of a medical implant including a guide wire attached to a medical implant;
[0042] FIG. 8B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 8A, where the distal end of the sleeve of the medical device is 25 adjacent the free end of the guide wire;
[0043] FIG. 8C illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 8A including the expandable component of the medical device capturing the medical implant;
_g-[0044] FIG. 9 illustrates a partially-sectioned schematic view of an embodiment of the medical device according to the invention including the expandable component in a substantially-deployed configuration covering the proximal pores of the distal protection filter;
[004] FIG. 10A illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 5A in accordance with the invention9 including the expandable component in a collapsed configuration and the distal end of the sleeve aligned with a collapsible medical implant;
[004dS] FIG. 10~ illustrates a partially-sectioned schematic view of the medical device of FIG.
10A including the expandable component in a partially-deployed cor~guration adjacent the to proximal portion of the collapsible medical implant; and [0047] FIG. l OC illustrates a partially-sectioned schematic view of the medical device of FIG.
10A including the expandable component in a substantially-deployed configuration capturing the medical implant in a substantially-collapsed state.
_g_ DESCRIPTION
[0048] Embodiments of the present invention are described below. The invention is not limited to these embodiments, and various modifications to the disclosed embodiments are also encompassed by the invention. ~ medical device according to the invention can be used to manipulate a medical implant in a patient9s body. In one embodiment, the medical device is used for capturing a medical implant in a patient such as, for example, a vascular distal protection filter or a cardiac septal occludes.
[004] Referring to FIG. 1A, a medical device 100 according to the invention includes a sleeve 102, an expandable component 104, and an actuator 142. The sleeve 102 includes a to proximal end 106, and a lumen 108 that extends longitudinally within at least a portion of the sleeve 102 and terminates at a distal end 110 of the sleeve 102. The distal end 110 of the sleeve 102 has a circumference 112. The expandable component 104 includes a first portion 114, a second portion 116 and a third portion 118. The first portion 114 of the expandable component 104 is permanently joined around the circumference of the distal end 110 of the sleeve 102 and 15 includes a lumen 122. The third portion 118 of the expandable component 104 is the portion that is closest to the proximal end 106 of the sleeve 102 when the expandable component 104 is in a collapsed state 120, as illustrated in FIG. RA. The intermediate or second portion 116 of the expandable component 104 extends between the first portion 114 and the third portion 118 and includes the lumen 122 that extends between the first portion 114 of the expandable component 20 104 and the third portion 118 of the expandable component 104. The lumen 122 of the expandable component 104 includes a depth 124.
[0050] In one embodiment according to the invention, the expandable component 104 is slideably moveable in the lumen 108 of the sleeve 102 transitioning between the collapsed configuration 120 through substantially deployed states illustrated in FIGS.
1B and 1C, to a 25 fully-deployed configuration 126, illustrated in FIG. 1D. In one embodiment, the actuator 142 reciprocatably slides the expandable component 104 between the collapsed configuration 120 and the fully-deployed configuration 126, and any configuration between the collapsed configuration 120 and the fully-deployed configuration 126, depending on the intended application of the medical device 100. Alternatively, the actuator 142 may actuate the sleeve 30 102 reciprocatably while the expandable component 104 is stationary.
[0051] Referring to FIG. 1A, in the collapsed configuration 120, the expandable component 104 is enclosed within the lumen 108 of the sleeve 102. The expandable component 104 in the collapsed configuration 120 includes a lumen 122 with a depth indicated by arrow 124. The depth 124 of the lumen 122 of the expandable component 104 decreases as the expandable component transitions from the collapsed confgguxation 120, illustrated in FIG. 1A, to the fully-deployed configuration 126, illustrated in FIG. 1D. In the fully-deployed state 126, the depth 124 is almost nil or close to zero.
[002] The configuration of the expandable component 104 when it transitions between the collapsed configuration 120 and the expanded configuration 126 is determined by the intended to application of the medical device 100 in a patient's body. For example, for application of the medical device for capturing a medical implant, referring to FIGS 1B and 1C, the expandable component 104 is configured between the collapsed configuration 120 and the fully-deployed configuration 126. As the expandable component 104 is deployed, the third portion 118 of the expandable component 104 moves toward the distal end 110 of the sleeve 102, pushing the 15 second portion 116 of the expandable component 104, which lies proximal to the first portion 114 when the expandable component 104 is in the collapsed configuration 120, beyond the distal end 110 of the sleeve 102. For example, referring to FIG. 1B, in an intermediate or partially-deployed configuration 128 of the expandable component 104, the third portion 118 of the expandable component 104 moves in a proximal direction toward the distal end 110 of the sleeve 20 102, resulting in at least a portion of the second portion 116 of the expandable component 104 extruded beyond the distal end 110 of the sleeve 102. Referring now to FIG. 1 C, a substantially-deployed configuration 130 of the expandable component 104 is illustrated. In this embodiment, the length of the extruded portion 132 of the expandable component 104 is greater than the length of the expandable component 104 that remains enclosed within the lumen 108 of 25 the sleeve 102. Referring to FIG. 1D, which depicts a fully-deployed configuration 126 of the expandable component 104, the entire length of the expandable component 104 is extruded beyond the distal end of the sleeve 102. The length of the extruded portion 132 of the expandable element 104 in the fully-deployed state 126 is the full length of the expandable element 104 within the lumen 108 of the sleeve 102 in the collapsed configuration 120. The 30 length of the extruded portion 132 of the expandable component 104 beyond the distal end 110 of the sleeve 102 is selected according to the intended application of the medical device 100 in the patient's body.
[0053] Referring again to FIGS. lA-1D, the length of the extruded portion 132 varies from none in the collapsed configuration 120, illustrated in FIG. 1A, to increasing magnitude in the various deployed states illustrated in FIGS. 1B-1D, with the length of the extruded portion 132 being maximal in the fully-deployed configuration 126, illustrated in FIG. 1D.
For example, in ~ne ~n'll2~d1111e11t, the e~~truded portion 132 formed by the expandable component 104 is shaped and sued for capturing a medical implant such as a prosthetic occluder in a patient's body.
Accordingly, the configuration of the expandable component 104 lies between the collapsed configuration 120 and the fully-deployed configuration 126.
[004] ~Jith continued reference to FIGS. lA-1D, in one embodiment, the expandable to component 104 has a poclcet with a depth 124. The first portion 114 of the expandable component 104 is open and has a rim 134 with a circumference 136. The third portion 118 of the expandable component 104 is closed and has a base 138 forming the bottom of the pocket.
The rim 134 of the expandable component 104 is joined to the distal end 110 of the sleeve 102 at a plurality of points about the circumference 136 of the rile 134. For example, the rim 134 of the expandable component 104 may be joined to the distal end 110 of the sleeve 102 by an adhesive, sutures, crimping, or heat welding, for example. In one embodiment according to the invention, the circumference 136 of the rim 134 of the expandable component 104 is joined to the circumference 112 of the distal end 110 of the sleeve 102.
[0055] In another embodiment according to the invention, referring now to FIG.
2A, the 2o expandable component 104 may be a tube. The base 13 8 of the tubular expandable component 104 may be imperforate or perforate. For example, illustrated in FIG. 2A, the base 138 may surround a hole 140. The hole 140 may be useful for axially slideable movement of, for example, a guide wire in the lumen 108 of the sleeve 102 and through the lumen 122 of the expandable component 104. In a particular embodiment, illustrated in FIG. 2B, the expandable component 104 is tubular having a cylindrical shape with an open first portion 114 and an open third portion 118. In yet another embodiment, illustrated in FIG. 2C, the expandable component 104 is funnel shaped having an open first portion 114 and an open or third portion 118.
[006] In all the foregoing aspects of the invention, the overall length of the medical device 100 is selected according to the intended application ofthe medical device 100 in the patient's 3o body. The overall length of the medical device 100 depends on the specific blood vessel in the patient's body in which the medical implant is located. Generally, the overall length will be in the range of about 25 cm to about 175 cm. In one embodiment, the overall length of the medical device 100 is about 100 cm to about 150 cm, and preferably about 120 cm.
Devices for different applications, or those intended for use with children, will be of different lengths.
[0057] The expandable component 104 of the medical device 100 may be made from a variety of materials that are flexible and largely atraumatic. Examples of such materials include, for example, polyester, nylon, and steel. In one embodiment, the es_pandable component 104 is a tube that is made from a braided material. The braided material can be manufactured in part or entirely from a plastic, a fabric, or a metal or any combinations of the above. In one embodiment, the braided material is made of a combination of polyester and steel. In a preferred embodiment, the steel is incorporated into the polyester. (severally, the ratio of steel to polyester l0 in the braided material ranges from about 0.2 to about 0.5 and preferably about 0.25. The braided material can either be single-stranded or mufti-stranded. The braided material can be formed as a mesh of individual filaments of materials such as, for example, polyester, polyethylene terephthalate or PET, polypropylene, nitinol, steel or any combinations of these materials. In a particular embodiment, the braided material is inverted over itself and secured to the distal end 110 of the sleeve 102. In another embodiment, the expandable component 104 is a woven or elastomeric tube or sock. Suitable materials for the manufacture of the expandable component 104 in the form of an elastomeric tube include at least in part, for example, PEBAX
(ATOFINA Chemicals, Inc., Philadelphia, PA), KR.ATON (I~raton Polymers, Houston, TX), C-Flex (silicone modified thermoplastic elastomers) (Consolidated Polymer Technologies, Largo, 2o FL), polyurethane, expandable polytetrafluoroethylene or PTFE or any combinations of these materials. In yet another embodiment, the expandable component 104 is a cylindrical mesh. In a preferred embodiment, the expandable component 104, in any configuration, includes a lubricious coating. Suitable materials for the manufacture of the lubricious coating include at least in part, for example, TEFLON (Dupont, Wilmington, DE), a hydrophilic coating, polyethylene oxide, hydrogel or any combinations of these materials.
[005] The maximum outer diameter of the expandable component 104 in the deployed configuration is dependent on its intended application inside a patient's body. The maximum outer diameter of the expandable component 104 in the deployed configuration must be no greater than the inside diameter of the blood vessel into which the medical device 100 is inserted.
For example, to capture an intravascular distal protection filter, the outer diameter of the expandable component 104 in a substantially-deployed configuration 130 typically is in the range of about 4 mm to about 8 mm, preferably about 6 mm, whereas to capture an interatrial septal occluder, the outer diameter of the expandable component 104 in a substantially-deployed configuration 130 typically is in the range of about 17 mm to about 43 mm, preferably about 25 [009] Similarly, the entire length of the expandable component 104 and accordingly, the length 132 of the expandable component 104 e~~truded beyond the distal end 110 of the sleeve 102 depends on the application of the medical device 100. For example, the length of the extruded portion 132 in the fully-deployed configuration, which is equal to the full length of the expandable element 104, typically is in the range of about 10 mm to about 30 mm, preferably about 25 ~nm when the medical implant intended to be captured is an intravascular distal to protection filter, whereas the length of the extruded portion 132 in the fully-deployed configuration typically is in the range of about 25 mm to about 100 mm, preferably about 90 mm when the medical implant intended to be captured is an interatrial septal occluder.
[0060] Referring now to FIGS. 3A and 3B, in one embodiment according to the invention, the medical device 100 includes an elongate member 144 axially positioned and slideably moveable 15 within the lumen 108 of the sleeve 102. The elongate member 144 includes a distal end 146 and a proximal end 148. In one embodiment, referring to FIG. 4A, the third portion 118 of the expandable component 104 is secured to the distal end 148 of the elongate member 144 and the rim 134 of the expandable component 104 is secured to the distal end 110 of the sleeve 102, for example, in an end to end or overlapping fashion. A variety.of conventional techniques can be 2o used for securing the distal end 146 of the elongate member 144 to the third portion 118 of the expandable component 104 including, for example, heat fusing, adhesive bonding, chemical bonding or mechanical attachment.
[0061] With continued reference to FIGS. 3A and 3B, in one embodiment, the elongate member 144 may be reciprocatably and axially moveable within the lumen 108 of the sleeve 25 102. For example, the elongate member 144 is axially moved distally until the expandable component 104 transitions from the collapsed configuration 120, illustrated in FIG. 3A, to a substantially-deployed configuration 130, illustrated in FIG. 3B. The expandable component 104 may be deployed into a shape suitable for capturing a medical implant by slideably moving the sleeve 102 distally relative to the expandable component 104.t. In a particular embodiment, 3o the expandable component 104 is deployed into a conical shape. The expandable component 104 may be deployed beyond the distal end 110 of the sleeve 102 into a shape suitable for capturing a medical implant by axial movement of the elongate member 142 relative to the sleeve 102, or, alternatively, by relative sliding motion of the sleeve 102 relative to the expandable component 104.
[0062] Referring now to FIG. 4A, in another embodiment of the medical device 100 in accordance with the invention, the elongate member 144 has ~. lumen 150. In a further emb~diment of the invention, the lumen 150 axially extends through the entire length of the elongate member 144. In a particular embodiment, illustrated in FIG. 4A, the lumen 122 of the expandable component 104 is continuous with the lumen 150 of the elongate member 144. The expandable component 104 may transition from the collapsed configuration 120, illustrated in FIG. 4~A, to the fully-deployed configuration 126, illustrated in FIG. 4B, by axial movement of l0 the elongate member 144 relative to the sleeve 102 beyond the distal end 110 of the sleeve 102, or alternatively, by relative sliding motion of the sleeve 102 relative to the expandable component 104. Referring to FIG. 4B, between the collapsed configuration 120 and the fully-deployed configuration 126, the expandable component 104 is deployed into substantially-deployed configuration 130 that includes a shape suitable for capturing a medical implant. In a 15 particular embodiment, the expandable component 104 has a conical shape for capturing a medical implant. In a further embodiment, a guide wire may be inserted via the proximal end 148 of the elongate member 144 through the lumen 150 of the elongate member 144 acid advanced through the lumen 122 of the expandable component 104 beyond the distal end 110 of the sleeve 102.
20 [0063] Referring now to FIG. 5A, in the substantially-deployed configuration 130, the expandable component 104 is shaped and sized to accommodate the shape and size of the medical implant intended to be captured. In a particular embodiment, illustrated in FIG. 5A, the expandable component 104 is deployed into a conical shape. In yet another embodiment, referring now to FIG. 5B, the expandable component 104 has a generally circulax cross-section.
25 [0064] Referring again to FIG. 5A, in one embodiment, the expandable component 104 includes flexible support arms 152 that provide increased rigidity to form the framework for the shape assumed by the expandable component 104 when at least a portion of the expandable component 104 is extruded beyond the distal end 110 of the sleeve 102. The arms 152 may be manufactured from a wire, such as spring wire. Referring now to FIG. SC, the flexible support 30 arms 152 occupy a reduced dimension in the radial direction when they are collapsed within the expandable component 104- in the collapsed configuration 120. Referring again to FIG. 5A, when the expandable component 104 is deployed beyond the distal end 110 of the sleeve 102, the flexible support arms 152are released and spring outward to form the framework for the shape of the expandable component 104 in a deployed position.
[006] The sleeve 102 is manufactured from biocompatible materials suitable for use inside a patient's body without causing damage to the vasculature. Suitable materials for the manufacture of the sleeve 102 include s~mthetic polymers such as polyethylene, polyurethane, polyglycolic acid, polyesters, polyamides, and mixtures, blends, copolymers thereof and any combinations of these materials. Preferred materials include polyesters such as polyfluorocarbons such as polytetrafluoroethylene (PTFE) with and without copolyrne.ri~ed hexafluoropropylene, and porous or nonporous polyurethanes. Especially preferred are the 1o expanded fluorocarbon polymers.
[0066] Included in the class of preferred fluoropolymers are polytetrafluoroethylene (PTFE), fluorinated ethylene propylene (FEP), polyethylene terephthalate (PET), copolymers of tetrafluoroethylene (TFE) and perfluoro (propyl vinyl ether) (PFA), homopolymers of polychlorotrifluoroethylene (PCTFE), and its copolymers with TFE, ethylene-chlorotrifluoroethylene (ECTFE), copolymers of ethylene-tetrafluoroethylene (ETFE), polyvinylidene fluoride (PVDF), and polyvinyfluoride (PVF).
[0067] Referring to FIG. 6, the outer diameter 154 of the sleeve 102 and the inner diameter 156 of the lumen 150 of the elongate member 144 depend on the application inside a patient's body for which the medical device 100 is intended. For example, for capturing or delivering an 2o intravascular distal protection filter, the outside diameter 154 of the sleeve 102 typically is in the range of about 0.4 mm to about 2.0 mm, preferably about 0.5 mm, and the inner diameter 156 of the elongate member 144 typically is in the range of about 0.2 mm to about 1.5 mm, preferably about 0.3 mm. Alternatively, for capturing or delivering a septal occluder, the outside diameter 154 of the sleeve 102 typically is in the range of 2 mm to about 6 mm, preferably about 5 mm, and the inner diameter 156 of the elongate member 144 typically is in the range of about 1.7 mm to about 5 mm, preferably about 4 mm.
[006] The elongate member 144 can be made from a variety of materials and configurations.
In one embodiment, the elongate member 144 is made from the same material as the sleeve 102.
In another embodiment, the elongate member 14~4~ and the sleeve 102 are manufactured from 3o different materials. Suitable materials for the manufacture ofthe elongate member 144 include, for example, synthetic polymers such as polyethylene, polyurethane, polyglycolic acid, PEBAX
(ATOFINA Chemicals, Inc., Philadelphia, PA), polyesters, polyamides, and mixtures, blends, copolymers thereof, and any combinations of these materials.
[006] In one embodiment, the sleeve 102 may be coated with a radio-opaque material that enables a health care practitioner to track the medical device 100 of the invention by an imaging device while the medical device is used in a patient. In another embodiment, the flexible support arms 152 nay be coated with a radio-opaque material, which enables a health care practitioner to visualise the expandable component 104 by an imaging device as the operator tracks and maneuvers the expandable component 104 between the collapsed configuration 120 and the deployed conf gurations during a medical procedure to capture or position a medical implant in a 1o patient's body.
[0070] In another aspect, the invention is a method for manipulating , for example, for delivering or capturing a medical implant in the body of a patient using the medical device 100 according to the invention. For example, referring now to FIGS. 7A-7C, in one embodiment according to the invention, the medical device 100 includes a guide wire 158 for delivering or capturing a medical implant 160 in a patient's body. In a particular embodiment, the medical implant 160 is an intravascular distal protection filter that includes a central lumen 162 through which the guide wire 158 may be advanced.
[0071] Referring now to FIG. 7A, according to the method of the invention, a health care practitioner inserts the guide wire 158 into the medical device 100 via the proximal end 148 of 2o the elongate member 144. The guide wire 158 is advanced proximally through the lumen 150 of the elongate member 144, the lumen 150 of the elongate member 144 being continuous with the lumen 122 of the expandable component 104.
[0072] Referring now to FIG. 7B, according to one embodiment of the invention, the guide wire 158 is advanced through the lumen 150 of the elongate member 144 into the lumen 122 of the expandable component 104. The medical device 100 is positioned relative to the medical implant 160 in the patient's body such that the lumen 162 of the medical implant 160 is aligned with the lumen 122 of the expandable component 104. With continued reference to 7B, in one embodiment, the guide wire 158 is advanced through the lumen 162 and beyond the distal portion of the medical implant 160.
[007] The guide wire 158 may be used for positioning the medical implant 160 relative to the medical device 100 to capture the medical implant 160 with the medical device 100, as well as for removal of the medical implant 160 from the patient's body. For example, the expandable component 104 of the medical device 100 is moved from the collapsed position 120, illustrated in FIG. 7A, to the substantially-deployed position 130 illustrated in FIG. 7C, for subsequent capture of the medical implant 160. In a particular embodiment, illustrated in FIG. 7C, the e~~pandable component 104 is deployed beyond the distal end 110 of the sleeve 102 to form a conical shape for capturing a medical implant. Referring to FIG. 7C, the e~apandable component 104 in the deployed position surrounds and captures the medical implant 160.
The guide wire 158 is removed along with the medical device 100 from the patient's body, thereby retrieving the medical implant 160 from the patient's body.
to [007.] Referring now to FIG. 8A, in another embodiment of the method of the invention, the medical device 100 may be used to insert or capture a medical implant having a guidewire 158 attached at its proximal end 166. Referring to FIG. 8B, the medical device 100 is positioned relative to the medical implant 160 such that the distal end 110 of the sleeve 102 is aligned with the free end 168 of the guide wire 158. In this embodiment, the guide wire 158 enters the 15 medical device 100 at the distal end 110 of the sleeve 102 via the lumen 122 of the expandable component 104 which is continuous with the lumen 150 of the elongate member 144. Referring to FIG. 8C, the medical device 100 is advanced over the guide wire 158 or the guide wire 158 is advanced into the distal end 110 of the sleeve 102 of the medical device 100 until the medical device 100 is adjacent the medical implant 160. The elongate member 144 is distally moved to 20 deploy the expandable component 104 into a substantially-deployed configuration 130 beyond the distal end 110 of the sleeve 102, for capturing the medical implant.
Theexpandable component 104 may also be deployed by distally moving the sleeve relative to the expandable component.
[0075] Referring now to FIG. 9, in a particular embodiment according to the invention, the 25 medical device 100 may be used to capture a distal protection filter 170 in a patient's body. A
distal protection filter is a medical implant used for capturing embolic material that is dislodged during a medical procedure such as, angioplasty. While retrieving the distal protection filter 170, the expandable component 104 of the medical device 100 covers the pores 172 on the proximal portion 174 of the distal protection filter 170 thereby preventing the egress of embolic debris 3o from the distal protection filter 170 during angioplasty.
[0076] Referring to FIGS. l0A-lOC, in one embodiment according to the invention, the medical device 100 is used for capturing a collapsible medical implant 178 inside a patient's body. The medical device 100 is positioned relative to the collapsible medical implant 178, as illustrated in FIG. 1 OA, such that the distal end 110 of the sleeve 102 is aligned with the proximal end 180 of the collapsible implant 178. In one embodiment, the maximum diameter of the collapsible medical implant 178 in an uncollapsed state 182 is greater than the maxixna~m di~a~neter 154 of the lumen of the sleeve 102.
[0077] Deferring to FIGS. 10~-lOC, the sleeve 102 is slideably moved relative to the expandable element 104, deploying the expandable component 104. beyond the distal end 110 of the sleeve 102. As the expandable component 104 transitions between the collapsed configuration, illustrated in FIG. 10A, and the substantially-deployed configuration, illustrated in to l OC, the extruded portion of the expandable component 104 radially compresses the medical implant 178, leading to collapse of the medical implant 178. The maximum diameter of the medical implant 178 decreases as the medical implant 178 transitions from the uncollapsed state 182 illustrated in FIG. 1 OA to the substantially-collapsed state 184, illustrated in FIG. 1 OC
[0078] In all the foregoing aspects of the invention, a health practitioner can use a medical 15 device 100 for the capture of medical implants used in the treatment of septal and atrial defects such as patent foramen ovals (PFO) and left atrial appendage (LAA).
[0079] In all the foregoing aspects of the invention, a health care practitioner can insert a medical device 100 of the invention inside a patient's body by a variety of means known in the art, including, for example, a catheter or a guide wire. In one method according to the invention, 2o a health care practitioner inserts a medical device 100 of the invention via a catheter inside a patient's body. Following the insertion of the medical device 100 into the patient's body using a catheter, the expandable component 104 of the medical device 100 is deployed beyond the distal end of the catheter in the proximity of the medical implant to be captured inside the patient's body. The medical implant is captured by the expandable component 104 in the deployed 25 configuration. Subsequent to the capture of the medical implant, both the medical device 100 and the captured medical implant are withdrawn into the larger bore diameter of the catheter for removal from the patient's body.
[0080] ~ther embodiments incorporating the concepts disclosed herein are within the spirit and scope of the invention. The described embodiments are illustrative of the invention and not 30 restrictive.
[0081] What is claimed is:
[~00~] ~ medical device according to the invention can be used to capture a medical implant for retrieval or delivery into a patient9 s body.
[000] In one aspect, the invention is directed to a medical device including a sleeve and an expandable component. The sleeve includes a lumen, a distal end and a proximal end and at least a portion of the expandable component is joined to the sleeve. The expandable component transitions between a collapsed state when the expandable component is enclosed by the sleeve, 1o and a deployed state when a portion of the expandable component is extended beyond the distal end of the sleeve. The expandable component is sized and shaped for manipulating a medical implant in a patient's body. For example, in one embodiment, manipulating includes capturing a medical implant for recovery from or delivering of the medical implant inside a patient's body.
[0010] In one embodiment, the medical device of the invention further includes an elongate 15 member. The elongate member includes a distal end and a proximal end and at least a portion of the elongate member is slideably moveable within the lumen of the sleeve. In one embodiment, at least a portion of the expandable component is joined to the elongate member. In a particular embodiment, at least a portion of the expandable component is joined to the distal end of the elongate member.
20 [0011] In various embodiments of the foregoing aspect of the invention, the expandable component of the medical device is joined to the distal end of the sleeve.
[0012] The expandable component is deployed by relative sliding motion of the sleeve and the expandable component. In one embodiment, the expandable component is reciprocatably moveable relative to the sleeve, wherein the sleeve is stationary. In another embodiment, the 25 sleeve is reciprocatably moveable relative to the expandable component, wherein the expandable component is stationary. The expandable component may also be deployed by relative sliding motion of the elongate member within the lumen of the sleeve relative to the sleeve.
[001] In one embodiment, the expandable component has a conical shape in the deployed state. The expandable component may be sized and shaped to manipulate a septal occluder. 'The 3o expandable component may also be sized and shaped to manipulate a distal protection filter.
[0014] In another aspect, the invention relates to methods for manipulating a medical implant in a patient's body using the aforementioned medical devices of the invention.
One method of the invention includes providing a medical device of the invention including a sleeve with a lumen, a distal end and a proximal end and an expandable component, where at least a portion of the distal portion of the expandable component is joined to the sleeve and the expandable comp~nent transitions between a c~llapsed state when the expandable c~mponent is encl~sed by the sleeve and a deployed state when a portion of the expandable component is extended beyond the distal end of the sleeve, the expandable component being sued and shaped for manipulating a, medical implant in a patient's body.
to [001] Another method of the invention includes providing the medical device that fiuther includes an elongate member that is slideably moveable within the lumen of the sleeve.
[0016] In one embodiment, manipulating a medical implant using a method according to the invention includes capturing a medical implant for delivery inside a patient's body using the medical device of the invention. In another embodiment, manipulating a medical implant using 15 the method according to the invention includes capturing a medical implant for retrieval from a patient's body.
[0017] In other aspects, the invention relates to a medical device for capturing a medical implant in a patient's body including a sleeve means, an expandable means, and means for deploying the expandable means beyond the sleeve means. At least a portion of the expandable 2o means is joined to the sleeve means and the expandable means transitions between a collapsed state when the expandable means is enclosed by the sleeve means and a deployed state when a portion of the expandable means is extended beyond the sleeve means, the expandable means being sized and shaped for capturing the medical implant in the patient's body.
[0018] In all embodiments of the foregoing aspects of the invention, the medical implant to be 25 captured can be a septal occluder, a stmt or a distal protection filter.
[0019] In all the foregoing aspects of the invention, the expandable component can be fabricated from several materials and can assume many configurations. Suitable materials include any material that is flexible, collapsible and atraumatic. In one embodiment, the expandable component lncludes a mesh that is cylindrical. In another embodiment, the 3o expandable component includes braided material. The expandable component can assume many configurations such as a braid or an elastomeric tube. The braid configuration can include multiple braids or a partial braid.
[0020] The directional terms distal and proximal require a point of reference.
The term "distal" refers to a direction that points away from inn operator of a~
medical device in accordance with the invention and into the patient's body. The term 'dproximal" refers to ~ direction that points toward an operator of the medical device in accordance with the invention and away from the patient's body.
[002] These and other objects, along with advantages and features of the present invention herein disclosed, will become apparent through reference to the following description, the accompanying drawings, and the claims. Furthermore, it is to be understood that the features of the various embodiments described herein are not mutually exclusive and can exist in various combinations and permutations.
BRIEF DESCRIPTION OF THE DRAWINGS
[0022] In the drawings, like reference characters generally refer to corresponding parts throughout the different views. The drawings are not necessarily to scale9 emphasis instead being placed on illuminating the principles and eon cepts of the invention.
[002] FIG. 1A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including the expandable component in a collapsed configuration;
[002] FIG. 1B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 1A including the expandable component in a partially-to deployed configuration;
[0025] FIG. 1 C illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 1A including the expandable component in a substantially-deployed configuration;
[0026] FIG. 1D illustrates a partially-sectioned schematic view of an embodiment of the 15 medical device illustrated in FIG. 1 A including the expandable component in a fully-deployed configuration;
[0027] FIG. 2A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including an expandable component with an open proximal section;
2o [0028] FIG. 2B illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a cylindrical expandable component with open distal and proximal portions;
[0029] FIG. 2C illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a funnel-shaped expandable component;
25 [000] FIG. 3A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including an elongate member;
[OO~I] FIG. 313 illustrates s a partially-sectioned schematic view of an embodiment of the medical devise illustrated in FIG. 3A in eluding the expandable component in a substantially-deployed configuration for capturing a medical implant;
_7_ [0032] FIG. 4A illustrates a partially-sectioned schematic view of an embodiment of a medical device in accordance with the invention including a lumen extending substantially through the entire length of the elongate member of the medical device;
[0033] FIG 4-B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 4~A in eluding the expandable component in a substantially-deployed configuration for capturing a medical implant;
[0034] FIG. 5A illustrates a schematic side-view of an embodiment of the expandable component of a medical device in accordance with the invention in a deployed configuration;
[003] FIG. 5B illustrates a schematic end-view of the deployed configuration of an to embodiment of the expandable component of the medical device illustrated in FIG. 5A;
[0036] FIG. 5C illustrates a schematic side-view of an embodiment of the expandable component illustrated in FIG. 5A in a collapsed configuration;
[0037] FIG. 6 is a cross-sectional view of the medical device of FIG. 4A
through 6-6.
[0038] FIG. 7A illustrates a partially-sectioned schematic view of an embodiment of the 15 medical device illustrated in FIG. 5A including a guide wire and a medical implant with a lumen;
[0039] FIG. 7B illustrates a partially-sectioned schematic view of the medical device illustrated in FIG. 7A, where the guide wire is extended substantially through the entire length of the medical device and the medical implant and beyond the distal end of the medical implant;
[0040] FIG. 7C illustrates a partially-sectioned schematic view of the medical device 2o illustrated in FIG. 7A including the expandable component capturing the medical implant;
[0041] FIG. 8A illustrates a schematic view of a medical implant including a guide wire attached to a medical implant;
[0042] FIG. 8B illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 8A, where the distal end of the sleeve of the medical device is 25 adjacent the free end of the guide wire;
[0043] FIG. 8C illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 8A including the expandable component of the medical device capturing the medical implant;
_g-[0044] FIG. 9 illustrates a partially-sectioned schematic view of an embodiment of the medical device according to the invention including the expandable component in a substantially-deployed configuration covering the proximal pores of the distal protection filter;
[004] FIG. 10A illustrates a partially-sectioned schematic view of an embodiment of the medical device illustrated in FIG. 5A in accordance with the invention9 including the expandable component in a collapsed configuration and the distal end of the sleeve aligned with a collapsible medical implant;
[004dS] FIG. 10~ illustrates a partially-sectioned schematic view of the medical device of FIG.
10A including the expandable component in a partially-deployed cor~guration adjacent the to proximal portion of the collapsible medical implant; and [0047] FIG. l OC illustrates a partially-sectioned schematic view of the medical device of FIG.
10A including the expandable component in a substantially-deployed configuration capturing the medical implant in a substantially-collapsed state.
_g_ DESCRIPTION
[0048] Embodiments of the present invention are described below. The invention is not limited to these embodiments, and various modifications to the disclosed embodiments are also encompassed by the invention. ~ medical device according to the invention can be used to manipulate a medical implant in a patient9s body. In one embodiment, the medical device is used for capturing a medical implant in a patient such as, for example, a vascular distal protection filter or a cardiac septal occludes.
[004] Referring to FIG. 1A, a medical device 100 according to the invention includes a sleeve 102, an expandable component 104, and an actuator 142. The sleeve 102 includes a to proximal end 106, and a lumen 108 that extends longitudinally within at least a portion of the sleeve 102 and terminates at a distal end 110 of the sleeve 102. The distal end 110 of the sleeve 102 has a circumference 112. The expandable component 104 includes a first portion 114, a second portion 116 and a third portion 118. The first portion 114 of the expandable component 104 is permanently joined around the circumference of the distal end 110 of the sleeve 102 and 15 includes a lumen 122. The third portion 118 of the expandable component 104 is the portion that is closest to the proximal end 106 of the sleeve 102 when the expandable component 104 is in a collapsed state 120, as illustrated in FIG. RA. The intermediate or second portion 116 of the expandable component 104 extends between the first portion 114 and the third portion 118 and includes the lumen 122 that extends between the first portion 114 of the expandable component 20 104 and the third portion 118 of the expandable component 104. The lumen 122 of the expandable component 104 includes a depth 124.
[0050] In one embodiment according to the invention, the expandable component 104 is slideably moveable in the lumen 108 of the sleeve 102 transitioning between the collapsed configuration 120 through substantially deployed states illustrated in FIGS.
1B and 1C, to a 25 fully-deployed configuration 126, illustrated in FIG. 1D. In one embodiment, the actuator 142 reciprocatably slides the expandable component 104 between the collapsed configuration 120 and the fully-deployed configuration 126, and any configuration between the collapsed configuration 120 and the fully-deployed configuration 126, depending on the intended application of the medical device 100. Alternatively, the actuator 142 may actuate the sleeve 30 102 reciprocatably while the expandable component 104 is stationary.
[0051] Referring to FIG. 1A, in the collapsed configuration 120, the expandable component 104 is enclosed within the lumen 108 of the sleeve 102. The expandable component 104 in the collapsed configuration 120 includes a lumen 122 with a depth indicated by arrow 124. The depth 124 of the lumen 122 of the expandable component 104 decreases as the expandable component transitions from the collapsed confgguxation 120, illustrated in FIG. 1A, to the fully-deployed configuration 126, illustrated in FIG. 1D. In the fully-deployed state 126, the depth 124 is almost nil or close to zero.
[002] The configuration of the expandable component 104 when it transitions between the collapsed configuration 120 and the expanded configuration 126 is determined by the intended to application of the medical device 100 in a patient's body. For example, for application of the medical device for capturing a medical implant, referring to FIGS 1B and 1C, the expandable component 104 is configured between the collapsed configuration 120 and the fully-deployed configuration 126. As the expandable component 104 is deployed, the third portion 118 of the expandable component 104 moves toward the distal end 110 of the sleeve 102, pushing the 15 second portion 116 of the expandable component 104, which lies proximal to the first portion 114 when the expandable component 104 is in the collapsed configuration 120, beyond the distal end 110 of the sleeve 102. For example, referring to FIG. 1B, in an intermediate or partially-deployed configuration 128 of the expandable component 104, the third portion 118 of the expandable component 104 moves in a proximal direction toward the distal end 110 of the sleeve 20 102, resulting in at least a portion of the second portion 116 of the expandable component 104 extruded beyond the distal end 110 of the sleeve 102. Referring now to FIG. 1 C, a substantially-deployed configuration 130 of the expandable component 104 is illustrated. In this embodiment, the length of the extruded portion 132 of the expandable component 104 is greater than the length of the expandable component 104 that remains enclosed within the lumen 108 of 25 the sleeve 102. Referring to FIG. 1D, which depicts a fully-deployed configuration 126 of the expandable component 104, the entire length of the expandable component 104 is extruded beyond the distal end of the sleeve 102. The length of the extruded portion 132 of the expandable element 104 in the fully-deployed state 126 is the full length of the expandable element 104 within the lumen 108 of the sleeve 102 in the collapsed configuration 120. The 30 length of the extruded portion 132 of the expandable component 104 beyond the distal end 110 of the sleeve 102 is selected according to the intended application of the medical device 100 in the patient's body.
[0053] Referring again to FIGS. lA-1D, the length of the extruded portion 132 varies from none in the collapsed configuration 120, illustrated in FIG. 1A, to increasing magnitude in the various deployed states illustrated in FIGS. 1B-1D, with the length of the extruded portion 132 being maximal in the fully-deployed configuration 126, illustrated in FIG. 1D.
For example, in ~ne ~n'll2~d1111e11t, the e~~truded portion 132 formed by the expandable component 104 is shaped and sued for capturing a medical implant such as a prosthetic occluder in a patient's body.
Accordingly, the configuration of the expandable component 104 lies between the collapsed configuration 120 and the fully-deployed configuration 126.
[004] ~Jith continued reference to FIGS. lA-1D, in one embodiment, the expandable to component 104 has a poclcet with a depth 124. The first portion 114 of the expandable component 104 is open and has a rim 134 with a circumference 136. The third portion 118 of the expandable component 104 is closed and has a base 138 forming the bottom of the pocket.
The rim 134 of the expandable component 104 is joined to the distal end 110 of the sleeve 102 at a plurality of points about the circumference 136 of the rile 134. For example, the rim 134 of the expandable component 104 may be joined to the distal end 110 of the sleeve 102 by an adhesive, sutures, crimping, or heat welding, for example. In one embodiment according to the invention, the circumference 136 of the rim 134 of the expandable component 104 is joined to the circumference 112 of the distal end 110 of the sleeve 102.
[0055] In another embodiment according to the invention, referring now to FIG.
2A, the 2o expandable component 104 may be a tube. The base 13 8 of the tubular expandable component 104 may be imperforate or perforate. For example, illustrated in FIG. 2A, the base 138 may surround a hole 140. The hole 140 may be useful for axially slideable movement of, for example, a guide wire in the lumen 108 of the sleeve 102 and through the lumen 122 of the expandable component 104. In a particular embodiment, illustrated in FIG. 2B, the expandable component 104 is tubular having a cylindrical shape with an open first portion 114 and an open third portion 118. In yet another embodiment, illustrated in FIG. 2C, the expandable component 104 is funnel shaped having an open first portion 114 and an open or third portion 118.
[006] In all the foregoing aspects of the invention, the overall length of the medical device 100 is selected according to the intended application ofthe medical device 100 in the patient's 3o body. The overall length of the medical device 100 depends on the specific blood vessel in the patient's body in which the medical implant is located. Generally, the overall length will be in the range of about 25 cm to about 175 cm. In one embodiment, the overall length of the medical device 100 is about 100 cm to about 150 cm, and preferably about 120 cm.
Devices for different applications, or those intended for use with children, will be of different lengths.
[0057] The expandable component 104 of the medical device 100 may be made from a variety of materials that are flexible and largely atraumatic. Examples of such materials include, for example, polyester, nylon, and steel. In one embodiment, the es_pandable component 104 is a tube that is made from a braided material. The braided material can be manufactured in part or entirely from a plastic, a fabric, or a metal or any combinations of the above. In one embodiment, the braided material is made of a combination of polyester and steel. In a preferred embodiment, the steel is incorporated into the polyester. (severally, the ratio of steel to polyester l0 in the braided material ranges from about 0.2 to about 0.5 and preferably about 0.25. The braided material can either be single-stranded or mufti-stranded. The braided material can be formed as a mesh of individual filaments of materials such as, for example, polyester, polyethylene terephthalate or PET, polypropylene, nitinol, steel or any combinations of these materials. In a particular embodiment, the braided material is inverted over itself and secured to the distal end 110 of the sleeve 102. In another embodiment, the expandable component 104 is a woven or elastomeric tube or sock. Suitable materials for the manufacture of the expandable component 104 in the form of an elastomeric tube include at least in part, for example, PEBAX
(ATOFINA Chemicals, Inc., Philadelphia, PA), KR.ATON (I~raton Polymers, Houston, TX), C-Flex (silicone modified thermoplastic elastomers) (Consolidated Polymer Technologies, Largo, 2o FL), polyurethane, expandable polytetrafluoroethylene or PTFE or any combinations of these materials. In yet another embodiment, the expandable component 104 is a cylindrical mesh. In a preferred embodiment, the expandable component 104, in any configuration, includes a lubricious coating. Suitable materials for the manufacture of the lubricious coating include at least in part, for example, TEFLON (Dupont, Wilmington, DE), a hydrophilic coating, polyethylene oxide, hydrogel or any combinations of these materials.
[005] The maximum outer diameter of the expandable component 104 in the deployed configuration is dependent on its intended application inside a patient's body. The maximum outer diameter of the expandable component 104 in the deployed configuration must be no greater than the inside diameter of the blood vessel into which the medical device 100 is inserted.
For example, to capture an intravascular distal protection filter, the outer diameter of the expandable component 104 in a substantially-deployed configuration 130 typically is in the range of about 4 mm to about 8 mm, preferably about 6 mm, whereas to capture an interatrial septal occluder, the outer diameter of the expandable component 104 in a substantially-deployed configuration 130 typically is in the range of about 17 mm to about 43 mm, preferably about 25 [009] Similarly, the entire length of the expandable component 104 and accordingly, the length 132 of the expandable component 104 e~~truded beyond the distal end 110 of the sleeve 102 depends on the application of the medical device 100. For example, the length of the extruded portion 132 in the fully-deployed configuration, which is equal to the full length of the expandable element 104, typically is in the range of about 10 mm to about 30 mm, preferably about 25 ~nm when the medical implant intended to be captured is an intravascular distal to protection filter, whereas the length of the extruded portion 132 in the fully-deployed configuration typically is in the range of about 25 mm to about 100 mm, preferably about 90 mm when the medical implant intended to be captured is an interatrial septal occluder.
[0060] Referring now to FIGS. 3A and 3B, in one embodiment according to the invention, the medical device 100 includes an elongate member 144 axially positioned and slideably moveable 15 within the lumen 108 of the sleeve 102. The elongate member 144 includes a distal end 146 and a proximal end 148. In one embodiment, referring to FIG. 4A, the third portion 118 of the expandable component 104 is secured to the distal end 148 of the elongate member 144 and the rim 134 of the expandable component 104 is secured to the distal end 110 of the sleeve 102, for example, in an end to end or overlapping fashion. A variety.of conventional techniques can be 2o used for securing the distal end 146 of the elongate member 144 to the third portion 118 of the expandable component 104 including, for example, heat fusing, adhesive bonding, chemical bonding or mechanical attachment.
[0061] With continued reference to FIGS. 3A and 3B, in one embodiment, the elongate member 144 may be reciprocatably and axially moveable within the lumen 108 of the sleeve 25 102. For example, the elongate member 144 is axially moved distally until the expandable component 104 transitions from the collapsed configuration 120, illustrated in FIG. 3A, to a substantially-deployed configuration 130, illustrated in FIG. 3B. The expandable component 104 may be deployed into a shape suitable for capturing a medical implant by slideably moving the sleeve 102 distally relative to the expandable component 104.t. In a particular embodiment, 3o the expandable component 104 is deployed into a conical shape. The expandable component 104 may be deployed beyond the distal end 110 of the sleeve 102 into a shape suitable for capturing a medical implant by axial movement of the elongate member 142 relative to the sleeve 102, or, alternatively, by relative sliding motion of the sleeve 102 relative to the expandable component 104.
[0062] Referring now to FIG. 4A, in another embodiment of the medical device 100 in accordance with the invention, the elongate member 144 has ~. lumen 150. In a further emb~diment of the invention, the lumen 150 axially extends through the entire length of the elongate member 144. In a particular embodiment, illustrated in FIG. 4A, the lumen 122 of the expandable component 104 is continuous with the lumen 150 of the elongate member 144. The expandable component 104 may transition from the collapsed configuration 120, illustrated in FIG. 4~A, to the fully-deployed configuration 126, illustrated in FIG. 4B, by axial movement of l0 the elongate member 144 relative to the sleeve 102 beyond the distal end 110 of the sleeve 102, or alternatively, by relative sliding motion of the sleeve 102 relative to the expandable component 104. Referring to FIG. 4B, between the collapsed configuration 120 and the fully-deployed configuration 126, the expandable component 104 is deployed into substantially-deployed configuration 130 that includes a shape suitable for capturing a medical implant. In a 15 particular embodiment, the expandable component 104 has a conical shape for capturing a medical implant. In a further embodiment, a guide wire may be inserted via the proximal end 148 of the elongate member 144 through the lumen 150 of the elongate member 144 acid advanced through the lumen 122 of the expandable component 104 beyond the distal end 110 of the sleeve 102.
20 [0063] Referring now to FIG. 5A, in the substantially-deployed configuration 130, the expandable component 104 is shaped and sized to accommodate the shape and size of the medical implant intended to be captured. In a particular embodiment, illustrated in FIG. 5A, the expandable component 104 is deployed into a conical shape. In yet another embodiment, referring now to FIG. 5B, the expandable component 104 has a generally circulax cross-section.
25 [0064] Referring again to FIG. 5A, in one embodiment, the expandable component 104 includes flexible support arms 152 that provide increased rigidity to form the framework for the shape assumed by the expandable component 104 when at least a portion of the expandable component 104 is extruded beyond the distal end 110 of the sleeve 102. The arms 152 may be manufactured from a wire, such as spring wire. Referring now to FIG. SC, the flexible support 30 arms 152 occupy a reduced dimension in the radial direction when they are collapsed within the expandable component 104- in the collapsed configuration 120. Referring again to FIG. 5A, when the expandable component 104 is deployed beyond the distal end 110 of the sleeve 102, the flexible support arms 152are released and spring outward to form the framework for the shape of the expandable component 104 in a deployed position.
[006] The sleeve 102 is manufactured from biocompatible materials suitable for use inside a patient's body without causing damage to the vasculature. Suitable materials for the manufacture of the sleeve 102 include s~mthetic polymers such as polyethylene, polyurethane, polyglycolic acid, polyesters, polyamides, and mixtures, blends, copolymers thereof and any combinations of these materials. Preferred materials include polyesters such as polyfluorocarbons such as polytetrafluoroethylene (PTFE) with and without copolyrne.ri~ed hexafluoropropylene, and porous or nonporous polyurethanes. Especially preferred are the 1o expanded fluorocarbon polymers.
[0066] Included in the class of preferred fluoropolymers are polytetrafluoroethylene (PTFE), fluorinated ethylene propylene (FEP), polyethylene terephthalate (PET), copolymers of tetrafluoroethylene (TFE) and perfluoro (propyl vinyl ether) (PFA), homopolymers of polychlorotrifluoroethylene (PCTFE), and its copolymers with TFE, ethylene-chlorotrifluoroethylene (ECTFE), copolymers of ethylene-tetrafluoroethylene (ETFE), polyvinylidene fluoride (PVDF), and polyvinyfluoride (PVF).
[0067] Referring to FIG. 6, the outer diameter 154 of the sleeve 102 and the inner diameter 156 of the lumen 150 of the elongate member 144 depend on the application inside a patient's body for which the medical device 100 is intended. For example, for capturing or delivering an 2o intravascular distal protection filter, the outside diameter 154 of the sleeve 102 typically is in the range of about 0.4 mm to about 2.0 mm, preferably about 0.5 mm, and the inner diameter 156 of the elongate member 144 typically is in the range of about 0.2 mm to about 1.5 mm, preferably about 0.3 mm. Alternatively, for capturing or delivering a septal occluder, the outside diameter 154 of the sleeve 102 typically is in the range of 2 mm to about 6 mm, preferably about 5 mm, and the inner diameter 156 of the elongate member 144 typically is in the range of about 1.7 mm to about 5 mm, preferably about 4 mm.
[006] The elongate member 144 can be made from a variety of materials and configurations.
In one embodiment, the elongate member 144 is made from the same material as the sleeve 102.
In another embodiment, the elongate member 14~4~ and the sleeve 102 are manufactured from 3o different materials. Suitable materials for the manufacture ofthe elongate member 144 include, for example, synthetic polymers such as polyethylene, polyurethane, polyglycolic acid, PEBAX
(ATOFINA Chemicals, Inc., Philadelphia, PA), polyesters, polyamides, and mixtures, blends, copolymers thereof, and any combinations of these materials.
[006] In one embodiment, the sleeve 102 may be coated with a radio-opaque material that enables a health care practitioner to track the medical device 100 of the invention by an imaging device while the medical device is used in a patient. In another embodiment, the flexible support arms 152 nay be coated with a radio-opaque material, which enables a health care practitioner to visualise the expandable component 104 by an imaging device as the operator tracks and maneuvers the expandable component 104 between the collapsed configuration 120 and the deployed conf gurations during a medical procedure to capture or position a medical implant in a 1o patient's body.
[0070] In another aspect, the invention is a method for manipulating , for example, for delivering or capturing a medical implant in the body of a patient using the medical device 100 according to the invention. For example, referring now to FIGS. 7A-7C, in one embodiment according to the invention, the medical device 100 includes a guide wire 158 for delivering or capturing a medical implant 160 in a patient's body. In a particular embodiment, the medical implant 160 is an intravascular distal protection filter that includes a central lumen 162 through which the guide wire 158 may be advanced.
[0071] Referring now to FIG. 7A, according to the method of the invention, a health care practitioner inserts the guide wire 158 into the medical device 100 via the proximal end 148 of 2o the elongate member 144. The guide wire 158 is advanced proximally through the lumen 150 of the elongate member 144, the lumen 150 of the elongate member 144 being continuous with the lumen 122 of the expandable component 104.
[0072] Referring now to FIG. 7B, according to one embodiment of the invention, the guide wire 158 is advanced through the lumen 150 of the elongate member 144 into the lumen 122 of the expandable component 104. The medical device 100 is positioned relative to the medical implant 160 in the patient's body such that the lumen 162 of the medical implant 160 is aligned with the lumen 122 of the expandable component 104. With continued reference to 7B, in one embodiment, the guide wire 158 is advanced through the lumen 162 and beyond the distal portion of the medical implant 160.
[007] The guide wire 158 may be used for positioning the medical implant 160 relative to the medical device 100 to capture the medical implant 160 with the medical device 100, as well as for removal of the medical implant 160 from the patient's body. For example, the expandable component 104 of the medical device 100 is moved from the collapsed position 120, illustrated in FIG. 7A, to the substantially-deployed position 130 illustrated in FIG. 7C, for subsequent capture of the medical implant 160. In a particular embodiment, illustrated in FIG. 7C, the e~~pandable component 104 is deployed beyond the distal end 110 of the sleeve 102 to form a conical shape for capturing a medical implant. Referring to FIG. 7C, the e~apandable component 104 in the deployed position surrounds and captures the medical implant 160.
The guide wire 158 is removed along with the medical device 100 from the patient's body, thereby retrieving the medical implant 160 from the patient's body.
to [007.] Referring now to FIG. 8A, in another embodiment of the method of the invention, the medical device 100 may be used to insert or capture a medical implant having a guidewire 158 attached at its proximal end 166. Referring to FIG. 8B, the medical device 100 is positioned relative to the medical implant 160 such that the distal end 110 of the sleeve 102 is aligned with the free end 168 of the guide wire 158. In this embodiment, the guide wire 158 enters the 15 medical device 100 at the distal end 110 of the sleeve 102 via the lumen 122 of the expandable component 104 which is continuous with the lumen 150 of the elongate member 144. Referring to FIG. 8C, the medical device 100 is advanced over the guide wire 158 or the guide wire 158 is advanced into the distal end 110 of the sleeve 102 of the medical device 100 until the medical device 100 is adjacent the medical implant 160. The elongate member 144 is distally moved to 20 deploy the expandable component 104 into a substantially-deployed configuration 130 beyond the distal end 110 of the sleeve 102, for capturing the medical implant.
Theexpandable component 104 may also be deployed by distally moving the sleeve relative to the expandable component.
[0075] Referring now to FIG. 9, in a particular embodiment according to the invention, the 25 medical device 100 may be used to capture a distal protection filter 170 in a patient's body. A
distal protection filter is a medical implant used for capturing embolic material that is dislodged during a medical procedure such as, angioplasty. While retrieving the distal protection filter 170, the expandable component 104 of the medical device 100 covers the pores 172 on the proximal portion 174 of the distal protection filter 170 thereby preventing the egress of embolic debris 3o from the distal protection filter 170 during angioplasty.
[0076] Referring to FIGS. l0A-lOC, in one embodiment according to the invention, the medical device 100 is used for capturing a collapsible medical implant 178 inside a patient's body. The medical device 100 is positioned relative to the collapsible medical implant 178, as illustrated in FIG. 1 OA, such that the distal end 110 of the sleeve 102 is aligned with the proximal end 180 of the collapsible implant 178. In one embodiment, the maximum diameter of the collapsible medical implant 178 in an uncollapsed state 182 is greater than the maxixna~m di~a~neter 154 of the lumen of the sleeve 102.
[0077] Deferring to FIGS. 10~-lOC, the sleeve 102 is slideably moved relative to the expandable element 104, deploying the expandable component 104. beyond the distal end 110 of the sleeve 102. As the expandable component 104 transitions between the collapsed configuration, illustrated in FIG. 10A, and the substantially-deployed configuration, illustrated in to l OC, the extruded portion of the expandable component 104 radially compresses the medical implant 178, leading to collapse of the medical implant 178. The maximum diameter of the medical implant 178 decreases as the medical implant 178 transitions from the uncollapsed state 182 illustrated in FIG. 1 OA to the substantially-collapsed state 184, illustrated in FIG. 1 OC
[0078] In all the foregoing aspects of the invention, a health practitioner can use a medical 15 device 100 for the capture of medical implants used in the treatment of septal and atrial defects such as patent foramen ovals (PFO) and left atrial appendage (LAA).
[0079] In all the foregoing aspects of the invention, a health care practitioner can insert a medical device 100 of the invention inside a patient's body by a variety of means known in the art, including, for example, a catheter or a guide wire. In one method according to the invention, 2o a health care practitioner inserts a medical device 100 of the invention via a catheter inside a patient's body. Following the insertion of the medical device 100 into the patient's body using a catheter, the expandable component 104 of the medical device 100 is deployed beyond the distal end of the catheter in the proximity of the medical implant to be captured inside the patient's body. The medical implant is captured by the expandable component 104 in the deployed 25 configuration. Subsequent to the capture of the medical implant, both the medical device 100 and the captured medical implant are withdrawn into the larger bore diameter of the catheter for removal from the patient's body.
[0080] ~ther embodiments incorporating the concepts disclosed herein are within the spirit and scope of the invention. The described embodiments are illustrative of the invention and not 30 restrictive.
[0081] What is claimed is:
Claims (24)
1. A medical device for manipulating a medical implant in a patient's body comprising:
a sleeve comprising a lumen, a distal end and a proximal end;
an expandable component , wherein at least a portion of the expandable component is joined to the sleeve, the expandable component transitioning between a collapsed configuration when the expandable component is enclosed by the sleeve, and a deployed configuration , wherein a portion of the expandable component is extended beyond the distal end of the sleeve.
a sleeve comprising a lumen, a distal end and a proximal end;
an expandable component , wherein at least a portion of the expandable component is joined to the sleeve, the expandable component transitioning between a collapsed configuration when the expandable component is enclosed by the sleeve, and a deployed configuration , wherein a portion of the expandable component is extended beyond the distal end of the sleeve.
2. The medical device of claim 1, wherein manipulating comprises capturing the medical implant.
3. The medical device of claim 2, wherein capturing comprises delivering the medical implant in the patient's body.
4. The medical device of claim 2, wherein capturing comprises retrieving a medical device from the patient's body.
5. The medical device of claim 1, wherein the expandable component is reciprocatably moveable relative to the sleeve.
6. The medical device of claim 1, wherein the sleeve is reciprocatably moveable relative to the expandable component.
7. The medical device of claim 1, wherein at least a portion of the expandable component is joined to the distal end of the sleeve.
8. The medical device of claim 1, wherein the expandable component comprises a conical shape in the deployed configuration.
9. The medical device of claim 1, further comprising an elongate member.
10. The medical device of claim 9, wherein the at least a portion of the expandable component is secured to the elongate member.
11. The medical device of claim 9, wherein the elongate member is slideably moveable within the lumen of the sleeve.
12. The medical device of claim 1, wherein the expandable component is sized and shaped to manipulate a septal occluder in a patient's body.
13. The medical device of claim 1, wherein the expandable component is sized and shaped to manipulate a distal protection filter in a patient's body.
14. The medical device of claim 1, wherein the expandable component comprises a mesh.
15. The medical device of claim 14, wherein the mesh is cylindrical.
16. The medical device of claim 1, wherein the expandable component comprises braided material.
17. The medical device of claim 1, wherein the expandable component comprises an elastomeric tube.
18. A method for manipulating a medical implant in a patient's body comprising:
providing a medical device comprising a sleeve comprising a lumen, a distal end and a proximal end and an expandable component, wherein at least a portion of the expandable component is joined to the sleeve, the expandable component transitioning between a collapsed configuration when the expandable component is enclosed by the sleeve, and a deployed configuration wherein a portion of the expandable component is extended beyond the distal end of the sleeve.
providing a medical device comprising a sleeve comprising a lumen, a distal end and a proximal end and an expandable component, wherein at least a portion of the expandable component is joined to the sleeve, the expandable component transitioning between a collapsed configuration when the expandable component is enclosed by the sleeve, and a deployed configuration wherein a portion of the expandable component is extended beyond the distal end of the sleeve.
19. The method of claim 18, wherein manipulating comprises capturing the medical implant.
20. The method of claim 19, wherein capturing comprises recovering the medical implant from the patient's body.
21. The method of claim 19, wherein capturing comprises delivering the medical implant inside the patient's body.
22. The method of claim 18, wherein the medical implant is selected from the group consisting of a septal occluder, a stent and a distal protection filter.
23. The method of claim 18, further comprising an elongate member slideably moveable within the lumen of the sleeve.
24. A medical device for capturing a medical implant in a patient's body comprising:
a sleeve means;
an expandable means, wherein at least a portion of the exapandable means is joined to the sleeve means, the expandable means transitioning between a collapsed configuration when the expandable means is enclosed by the sleeve means, and a deployed configuration, wherein a portion of the expandable means is extended beyond the sleeve means; and means for deploying the expandable means beyond the sleeve means.
a sleeve means;
an expandable means, wherein at least a portion of the exapandable means is joined to the sleeve means, the expandable means transitioning between a collapsed configuration when the expandable means is enclosed by the sleeve means, and a deployed configuration, wherein a portion of the expandable means is extended beyond the sleeve means; and means for deploying the expandable means beyond the sleeve means.
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Families Citing this family (124)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100030256A1 (en) * | 1997-11-12 | 2010-02-04 | Genesis Technologies Llc | Medical Devices and Methods |
US9498604B2 (en) * | 1997-11-12 | 2016-11-22 | Genesis Technologies Llc | Medical device and method |
US8468678B2 (en) | 2002-10-02 | 2013-06-25 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
US7998163B2 (en) * | 2002-10-03 | 2011-08-16 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
US7658747B2 (en) | 2003-03-12 | 2010-02-09 | Nmt Medical, Inc. | Medical device for manipulation of a medical implant |
JP4731471B2 (en) * | 2003-04-16 | 2011-07-27 | ジェネシス・テクノロジーズ・エルエルシー | Medical devices and methods |
US20050159772A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Sheath for use with an embolic protection filtering device |
US20050159773A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Expandable retrieval device with dilator tip |
US20050192626A1 (en) | 2004-01-30 | 2005-09-01 | Nmt Medical, Inc. | Devices, systems, and methods for closure of cardiac openings |
US20080015569A1 (en) | 2005-02-02 | 2008-01-17 | Voyage Medical, Inc. | Methods and apparatus for treatment of atrial fibrillation |
US8078266B2 (en) | 2005-10-25 | 2011-12-13 | Voyage Medical, Inc. | Flow reduction hood systems |
US7930016B1 (en) | 2005-02-02 | 2011-04-19 | Voyage Medical, Inc. | Tissue closure system |
US11478152B2 (en) | 2005-02-02 | 2022-10-25 | Intuitive Surgical Operations, Inc. | Electrophysiology mapping and visualization system |
US9510732B2 (en) | 2005-10-25 | 2016-12-06 | Intuitive Surgical Operations, Inc. | Methods and apparatus for efficient purging |
US7860556B2 (en) | 2005-02-02 | 2010-12-28 | Voyage Medical, Inc. | Tissue imaging and extraction systems |
US7860555B2 (en) * | 2005-02-02 | 2010-12-28 | Voyage Medical, Inc. | Tissue visualization and manipulation system |
US10064540B2 (en) | 2005-02-02 | 2018-09-04 | Intuitive Surgical Operations, Inc. | Visualization apparatus for transseptal access |
US8050746B2 (en) | 2005-02-02 | 2011-11-01 | Voyage Medical, Inc. | Tissue visualization device and method variations |
US8137333B2 (en) | 2005-10-25 | 2012-03-20 | Voyage Medical, Inc. | Delivery of biological compounds to ischemic and/or infarcted tissue |
US7918787B2 (en) | 2005-02-02 | 2011-04-05 | Voyage Medical, Inc. | Tissue visualization and manipulation systems |
US7993362B2 (en) * | 2005-02-16 | 2011-08-09 | Boston Scientific Scimed, Inc. | Filter with positioning and retrieval devices and methods |
JP4885482B2 (en) * | 2005-06-01 | 2012-02-29 | オリンパスメディカルシステムズ株式会社 | Endoscopic catheter |
US8038704B2 (en) * | 2005-07-27 | 2011-10-18 | Paul S. Sherburne | Stent and other objects removal from a body |
US8221310B2 (en) | 2005-10-25 | 2012-07-17 | Voyage Medical, Inc. | Tissue visualization device and method variations |
US9034006B2 (en) * | 2005-12-01 | 2015-05-19 | Atritech, Inc. | Method and apparatus for retrieving an embolized implant |
US20070225750A1 (en) * | 2006-03-10 | 2007-09-27 | Brooke Ren | Embolic protection systems |
JP4925728B2 (en) * | 2006-05-30 | 2012-05-09 | ニプロ株式会社 | Device for capturing scattered foreign matter |
JP4925729B2 (en) * | 2006-05-30 | 2012-05-09 | ニプロ株式会社 | Percutaneous thrombectomy device |
US9055906B2 (en) | 2006-06-14 | 2015-06-16 | Intuitive Surgical Operations, Inc. | In-vivo visualization systems |
ATE419814T1 (en) * | 2006-07-24 | 2009-01-15 | Cardiatis Sa | DEVICE FOR THE REVERSIBLE INSERTION OF AN ENDOPROSTHESIS |
JP2010502313A (en) | 2006-09-01 | 2010-01-28 | ボエッジ メディカル, インコーポレイテッド | Method and apparatus for the treatment of atrial fibrillation |
US20080097476A1 (en) | 2006-09-01 | 2008-04-24 | Voyage Medical, Inc. | Precision control systems for tissue visualization and manipulation assemblies |
US10004388B2 (en) | 2006-09-01 | 2018-06-26 | Intuitive Surgical Operations, Inc. | Coronary sinus cannulation |
JPWO2008041755A1 (en) * | 2006-10-04 | 2010-02-04 | 東京電力株式会社 | AC / DC converter |
US10335131B2 (en) | 2006-10-23 | 2019-07-02 | Intuitive Surgical Operations, Inc. | Methods for preventing tissue migration |
US10624621B2 (en) | 2006-11-07 | 2020-04-21 | Corvia Medical, Inc. | Devices and methods for the treatment of heart failure |
US8460372B2 (en) | 2006-11-07 | 2013-06-11 | Dc Devices, Inc. | Prosthesis for reducing intra-cardiac pressure having an embolic filter |
US20110257723A1 (en) | 2006-11-07 | 2011-10-20 | Dc Devices, Inc. | Devices and methods for coronary sinus pressure relief |
US9232997B2 (en) | 2006-11-07 | 2016-01-12 | Corvia Medical, Inc. | Devices and methods for retrievable intra-atrial implants |
US10413284B2 (en) | 2006-11-07 | 2019-09-17 | Corvia Medical, Inc. | Atrial pressure regulation with control, sensing, monitoring and therapy delivery |
US20080183036A1 (en) | 2006-12-18 | 2008-07-31 | Voyage Medical, Inc. | Systems and methods for unobstructed visualization and ablation |
US9226648B2 (en) | 2006-12-21 | 2016-01-05 | Intuitive Surgical Operations, Inc. | Off-axis visualization systems |
US8131350B2 (en) | 2006-12-21 | 2012-03-06 | Voyage Medical, Inc. | Stabilization of visualization catheters |
EP2148608A4 (en) | 2007-04-27 | 2010-04-28 | Voyage Medical Inc | Complex shape steerable tissue visualization and manipulation catheter |
US8657805B2 (en) | 2007-05-08 | 2014-02-25 | Intuitive Surgical Operations, Inc. | Complex shape steerable tissue visualization and manipulation catheter |
US8709008B2 (en) | 2007-05-11 | 2014-04-29 | Intuitive Surgical Operations, Inc. | Visual electrode ablation systems |
AR062010A3 (en) * | 2007-07-20 | 2008-08-10 | Ernesto Odon Jorge | REMOVAL DEVICE OF ELEMENTS CONTAINED IN A CAVITY |
US8235985B2 (en) | 2007-08-31 | 2012-08-07 | Voyage Medical, Inc. | Visualization and ablation system variations |
WO2009052432A2 (en) | 2007-10-19 | 2009-04-23 | Coherex Medical, Inc. | Medical device for modification of left atrial appendange and related systems and methods |
US11589880B2 (en) | 2007-12-20 | 2023-02-28 | Angiodynamics, Inc. | System and methods for removing undesirable material within a circulatory system utilizing during a surgical procedure |
US8734374B2 (en) | 2007-12-20 | 2014-05-27 | Angiodynamics, Inc. | Systems and methods for removing undesirable material within a circulatory system during a surgical procedure |
US10517617B2 (en) | 2007-12-20 | 2019-12-31 | Angiodynamics, Inc. | Systems and methods for removing undesirable material within a circulatory system utilizing a balloon catheter |
DE102008005070A1 (en) * | 2008-01-18 | 2009-07-30 | Siemens Audiologische Technik Gmbh | Cavity examination device |
JP2009178518A (en) * | 2008-02-01 | 2009-08-13 | Nipro Corp | Medical tubular body, thrombus capturing member collecting sheath, thrombus collecting catheter, and balloon catheter |
US8858609B2 (en) | 2008-02-07 | 2014-10-14 | Intuitive Surgical Operations, Inc. | Stent delivery under direct visualization |
US9101735B2 (en) | 2008-07-07 | 2015-08-11 | Intuitive Surgical Operations, Inc. | Catheter control systems |
US8034095B2 (en) | 2008-08-29 | 2011-10-11 | Cook Medical Technologies Llc | Intraluminal system for retrieving an implantable medical device |
US8894643B2 (en) | 2008-10-10 | 2014-11-25 | Intuitive Surgical Operations, Inc. | Integral electrode placement and connection systems |
US8333012B2 (en) | 2008-10-10 | 2012-12-18 | Voyage Medical, Inc. | Method of forming electrode placement and connection systems |
US9468364B2 (en) | 2008-11-14 | 2016-10-18 | Intuitive Surgical Operations, Inc. | Intravascular catheter with hood and image processing systems |
WO2010081033A1 (en) | 2009-01-08 | 2010-07-15 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
US9649115B2 (en) | 2009-06-17 | 2017-05-16 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
US10064628B2 (en) | 2009-06-17 | 2018-09-04 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
CA2958338C (en) * | 2009-06-17 | 2019-04-16 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
US10631969B2 (en) * | 2009-06-17 | 2020-04-28 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
US9351716B2 (en) | 2009-06-17 | 2016-05-31 | Coherex Medical, Inc. | Medical device and delivery system for modification of left atrial appendage and methods thereof |
US9757107B2 (en) | 2009-09-04 | 2017-09-12 | Corvia Medical, Inc. | Methods and devices for intra-atrial shunts having adjustable sizes |
US9539081B2 (en) | 2009-12-02 | 2017-01-10 | Surefire Medical, Inc. | Method of operating a microvalve protection device |
AU2011210741B2 (en) * | 2010-01-29 | 2013-08-15 | Corvia Medical, Inc. | Devices and methods for reducing venous pressure |
JP5730909B2 (en) | 2010-01-29 | 2015-06-10 | ディーシー ディヴァイシーズ インコーポレイテッド | Device and system for treating heart failure |
US8694071B2 (en) | 2010-02-12 | 2014-04-08 | Intuitive Surgical Operations, Inc. | Image stabilization techniques and methods |
US9814522B2 (en) | 2010-04-06 | 2017-11-14 | Intuitive Surgical Operations, Inc. | Apparatus and methods for ablation efficacy |
US9561094B2 (en) | 2010-07-23 | 2017-02-07 | Nfinium Vascular Technologies, Llc | Devices and methods for treating venous diseases |
US8696732B2 (en) * | 2010-08-04 | 2014-04-15 | Boston Scientific Scimed, Inc. | Stent delivery system |
US10039900B2 (en) | 2010-09-07 | 2018-08-07 | Angiodynamics, Inc. | Fluid delivery and treatment device and method of use |
US9770319B2 (en) * | 2010-12-01 | 2017-09-26 | Surefire Medical, Inc. | Closed tip dynamic microvalve protection device |
CN103635226B (en) | 2011-02-10 | 2017-06-30 | 可维亚媒体公司 | Device for setting up and keeping intra-atrial pressure power release aperture |
US9055964B2 (en) | 2011-03-15 | 2015-06-16 | Angio Dynamics, Inc. | Device and method for removing material from a hollow anatomical structure |
AR081564A1 (en) | 2011-06-02 | 2012-10-03 | Desarrollos Tecnologicos Device S R L | AN EXTRACTION DEVICE FOR ELEMENTS CONTAINED IN CAVES, USING A BAG FOR EXTRACTION AND AN APPLICATOR |
WO2013055604A1 (en) * | 2011-10-11 | 2013-04-18 | Boston Scientific Scimed, Inc. | Recapture sheath |
US10010437B2 (en) | 2011-10-17 | 2018-07-03 | W. L. Gore & Associates, Inc. | Endoluminal device retrieval devices and related systems and methods |
EP4324409A3 (en) * | 2011-11-01 | 2024-03-13 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
WO2013096965A1 (en) | 2011-12-22 | 2013-06-27 | Dc Devices, Inc. | Methods and devices for intra-atrial devices having selectable flow rates |
US9005155B2 (en) | 2012-02-03 | 2015-04-14 | Dc Devices, Inc. | Devices and methods for treating heart failure |
US10588611B2 (en) | 2012-04-19 | 2020-03-17 | Corvia Medical Inc. | Implant retention attachment and method of use |
US9649480B2 (en) | 2012-07-06 | 2017-05-16 | Corvia Medical, Inc. | Devices and methods of treating or ameliorating diastolic heart failure through pulmonary valve intervention |
WO2014020590A1 (en) * | 2012-07-29 | 2014-02-06 | V.V.T. Med Ltd. | Ablation catheter for blood vessel ablation and methods of using thereof |
US9775636B2 (en) | 2013-03-12 | 2017-10-03 | Corvia Medical, Inc. | Devices, systems, and methods for treating heart failure |
EP3666227A1 (en) | 2013-06-14 | 2020-06-17 | Avantec Vascular Corporation | Inferior vena cava filter and retrieval systems |
US10675450B2 (en) | 2014-03-12 | 2020-06-09 | Corvia Medical, Inc. | Devices and methods for treating heart failure |
US9968740B2 (en) | 2014-03-25 | 2018-05-15 | Surefire Medical, Inc. | Closed tip dynamic microvalve protection device |
CN105792879A (en) | 2014-06-04 | 2016-07-20 | 恩菲纽姆血管技术有限公司 | Low radial force vascular device and method of occlusion |
US11110286B2 (en) | 2014-06-10 | 2021-09-07 | Biotronik Se & Co. Kg | Delivery system for an implantable medical device |
EP2954930B1 (en) * | 2014-06-10 | 2019-04-10 | BIOTRONIK SE & Co. KG | Delivery system for an implantable medical device |
WO2016014821A1 (en) | 2014-07-23 | 2016-01-28 | Corvia Medical, Inc. | Devices and methods for treating heart failure |
US10314634B2 (en) | 2014-11-04 | 2019-06-11 | Avantec Vascular Corporation | Catheter device with longitudinally expanding interior components for compressing cancellous bone |
US10278804B2 (en) * | 2014-12-12 | 2019-05-07 | Avantec Vascular Corporation | IVC filter retrieval systems with releasable capture feature |
US20160166372A1 (en) * | 2014-12-12 | 2016-06-16 | Avantec Vascular Corporation | Ivc filter retrieval systems with interposed support members |
US20160287839A1 (en) | 2015-03-31 | 2016-10-06 | Surefire Medical, Inc. | Apparatus and Method for Infusing an Immunotherapy Agent to a Solid Tumor for Treatment |
FI3288493T3 (en) * | 2015-04-29 | 2023-01-31 | Stent delivery system | |
CN108778183B (en) * | 2015-12-10 | 2021-07-13 | 阿万泰血管公司 | IVC filter recovery system with multiple capture modes |
CN108697497A (en) * | 2015-12-10 | 2018-10-23 | 阿万泰血管公司 | IVC filter recovery system sheaths improve |
WO2017139463A1 (en) * | 2016-02-09 | 2017-08-17 | Kassab Ghassan S | Devices, systems, and methods for use with suction within a mammalian body |
US10780250B1 (en) | 2016-09-19 | 2020-09-22 | Surefire Medical, Inc. | System and method for selective pressure-controlled therapeutic delivery |
US11400263B1 (en) | 2016-09-19 | 2022-08-02 | Trisalus Life Sciences, Inc. | System and method for selective pressure-controlled therapeutic delivery |
US10874499B2 (en) | 2016-12-22 | 2020-12-29 | Avantec Vascular Corporation | Systems, devices, and methods for retrieval systems having a tether |
AU2018200129A1 (en) * | 2017-02-21 | 2018-09-06 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
US10588636B2 (en) | 2017-03-20 | 2020-03-17 | Surefire Medical, Inc. | Dynamic reconfigurable microvalve protection device |
US10850095B2 (en) * | 2017-08-08 | 2020-12-01 | Pulse Biosciences, Inc. | Treatment of tissue by the application of energy |
US11590345B2 (en) | 2017-08-08 | 2023-02-28 | Pulse Biosciences, Inc. | Treatment of tissue by the application of energy |
US10857347B2 (en) | 2017-09-19 | 2020-12-08 | Pulse Biosciences, Inc. | Treatment instrument and high-voltage connectors for robotic surgical system |
CN112584799A (en) | 2018-06-29 | 2021-03-30 | 阿万泰血管公司 | Systems and methods for implants and deployment devices |
US11850398B2 (en) | 2018-08-01 | 2023-12-26 | Trisalus Life Sciences, Inc. | Systems and methods for pressure-facilitated therapeutic agent delivery |
US11338117B2 (en) | 2018-10-08 | 2022-05-24 | Trisalus Life Sciences, Inc. | Implantable dual pathway therapeutic agent delivery port |
US11571569B2 (en) | 2019-02-15 | 2023-02-07 | Pulse Biosciences, Inc. | High-voltage catheters for sub-microsecond pulsing |
US11369355B2 (en) | 2019-06-17 | 2022-06-28 | Coherex Medical, Inc. | Medical device and system for occluding a tissue opening and method thereof |
WO2021101622A1 (en) | 2019-11-21 | 2021-05-27 | W. L. Gore & Associates, Inc. | Delivery systems and methods for implantable cardiac assist devices |
US11648020B2 (en) | 2020-02-07 | 2023-05-16 | Angiodynamics, Inc. | Device and method for manual aspiration and removal of an undesirable material |
EP4138649A1 (en) | 2020-04-23 | 2023-03-01 | Shifamed Holdings, LLC | Intracardiac sensors with switchable configurations and associated systems and methods |
EP4203847A4 (en) | 2020-08-25 | 2024-02-28 | Shifamed Holdings Llc | Adjustable interatrial shunts and associated systems and methods |
EP4243915A1 (en) * | 2020-11-12 | 2023-09-20 | Shifamed Holdings, LLC | Adjustable implantable devices and associated methods |
US11812969B2 (en) | 2020-12-03 | 2023-11-14 | Coherex Medical, Inc. | Medical device and system for occluding a tissue opening and method thereof |
US20220233204A1 (en) * | 2021-01-25 | 2022-07-28 | DePuy Synthes Products, Inc. | Anchoring and Non-Occluding Intravascular Device for Use During Clot Removal Via Aspiration and/or Mechanical Extraction Device |
AU2023204303B1 (en) * | 2023-05-09 | 2023-11-09 | Venus Medtech (Hangzhou) Inc. | Expandable sheath for transcatheter delivery system and delivery system |
Family Cites Families (239)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3050066A (en) * | 1958-12-31 | 1962-08-21 | Wilbur R Koehn | Retention catheters |
US3502069A (en) * | 1965-10-20 | 1970-03-24 | Daniel Silverman | Method and apparatus for placing in and retrieving a tubular probe from a body cavity |
US3800781A (en) * | 1972-05-30 | 1974-04-02 | K Zalucki | Specimen-taking device |
US3874388A (en) * | 1973-02-12 | 1975-04-01 | Ochsner Med Found Alton | Shunt defect closure system |
US3875648A (en) * | 1973-04-04 | 1975-04-08 | Dennison Mfg Co | Fastener attachment apparatus and method |
US3924631A (en) | 1973-12-06 | 1975-12-09 | Altair Inc | Magnetic clamp |
US4006747A (en) * | 1975-04-23 | 1977-02-08 | Ethicon, Inc. | Surgical method |
US4007743A (en) * | 1975-10-20 | 1977-02-15 | American Hospital Supply Corporation | Opening mechanism for umbrella-like intravascular shunt defect closure device |
US4425908A (en) * | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
US4606347A (en) * | 1983-03-25 | 1986-08-19 | Thomas J. Fogarty | Inverted balloon catheter having sealed through lumen |
US4696300A (en) | 1985-04-11 | 1987-09-29 | Dennison Manufacturing Company | Fastener for joining materials |
US4650466A (en) * | 1985-11-01 | 1987-03-17 | Angiobrade Partners | Angioplasty device |
US4710192A (en) | 1985-12-30 | 1987-12-01 | Liotta Domingo S | Diaphragm and method for occlusion of the descending thoracic aorta |
AU610119B2 (en) | 1987-01-13 | 1991-05-16 | Terumo Kabushiki Kaisha | Balloon catheter and production thereof |
US4836204A (en) | 1987-07-06 | 1989-06-06 | Landymore Roderick W | Method for effecting closure of a perforation in the septum of the heart |
EP0352325A4 (en) | 1988-01-12 | 1990-05-14 | Ki Nii Nejrokhirurgii | Occluding device. |
IT1216042B (en) * | 1988-03-09 | 1990-02-22 | Carlo Rebuffat | AUTOMATIC TOOL FOR TOBACCO BAG SUTURES FOR SURGICAL USE. |
US4902508A (en) * | 1988-07-11 | 1990-02-20 | Purdue Research Foundation | Tissue graft composition |
US4956178A (en) | 1988-07-11 | 1990-09-11 | Purdue Research Foundation | Tissue graft composition |
US4921484A (en) * | 1988-07-25 | 1990-05-01 | Cordis Corporation | Mesh balloon catheter device |
US4946440A (en) | 1988-10-05 | 1990-08-07 | Hall John E | Evertible membrane catheter and method of use |
FR2641692A1 (en) * | 1989-01-17 | 1990-07-20 | Nippon Zeon Co | Plug for closing an opening for a medical application, and device for the closure plug making use thereof |
US5073166A (en) | 1989-02-15 | 1991-12-17 | Medical Innovations Corporation | Method and apparatus for emplacement of a gastrostomy catheter |
US5100429A (en) * | 1989-04-28 | 1992-03-31 | C. R. Bard, Inc. | Endovascular stent and delivery system |
US5620461A (en) * | 1989-05-29 | 1997-04-15 | Muijs Van De Moer; Wouter M. | Sealing device |
US4985014A (en) * | 1989-07-11 | 1991-01-15 | Orejola Wilmo C | Ventricular venting loop |
US5030199A (en) | 1989-12-11 | 1991-07-09 | Medical Engineering Corporation | Female incontinence control device with magnetically operable valve and method |
DE69102515T2 (en) | 1990-04-02 | 1994-10-20 | Kanji Inoue | DEVICE FOR CLOSING A SHUTTER OPENING BY MEANS OF A NON-OPERATIONAL METHOD. |
US5021059A (en) | 1990-05-07 | 1991-06-04 | Kensey Nash Corporation | Plug device with pulley for sealing punctures in tissue and methods of use |
US5037433A (en) | 1990-05-17 | 1991-08-06 | Wilk Peter J | Endoscopic suturing device and related method and suture |
US5041129A (en) | 1990-07-02 | 1991-08-20 | Acufex Microsurgical, Inc. | Slotted suture anchor and method of anchoring a suture |
US5057114A (en) | 1990-09-18 | 1991-10-15 | Cook Incorporated | Medical retrieval basket |
DE69133618D1 (en) * | 1990-10-09 | 2009-07-30 | Medtronic Inc | Surgical device for the manipulation of tissue |
US5190528A (en) * | 1990-10-19 | 1993-03-02 | Boston University | Percutaneous transseptal left atrial cannulation system |
US5372146A (en) | 1990-11-06 | 1994-12-13 | Branch; Thomas P. | Method and apparatus for re-approximating tissue |
US5129882A (en) | 1990-12-27 | 1992-07-14 | Novoste Corporation | Wound clotting device and method of using same |
US5370647A (en) * | 1991-01-23 | 1994-12-06 | Surgical Innovations, Inc. | Tissue and organ extractor |
US5108420A (en) * | 1991-02-01 | 1992-04-28 | Temple University | Aperture occlusion device |
US5112310A (en) | 1991-02-06 | 1992-05-12 | Grobe James L | Apparatus and methods for percutaneous endoscopic gastrostomy |
US5257637A (en) | 1991-03-22 | 1993-11-02 | El Gazayerli Mohamed M | Method for suture knot placement and tying |
US5176687A (en) * | 1991-05-10 | 1993-01-05 | Hasson Harrith M | Disposable pouch container for isolation and retrieval of tissues removed at laparoscopy |
DE69229539T2 (en) | 1991-11-05 | 2000-02-17 | Childrens Medical Center | Occlusion device for repairing heart and vascular defects |
EP0541063B1 (en) | 1991-11-05 | 1998-09-02 | The Children's Medical Center Corporation | Improved occluder for repair of cardiac and vascular defects |
US5222974A (en) | 1991-11-08 | 1993-06-29 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
US5282827A (en) * | 1991-11-08 | 1994-02-01 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
IL100721A (en) * | 1992-01-21 | 1996-12-05 | Milo Simcha | Punch for opening passages between two compartments |
DE69334196T2 (en) | 1992-01-21 | 2009-01-02 | Regents Of The University Of Minnesota, Minneapolis | Closure device of a septal defect |
US5649950A (en) | 1992-01-22 | 1997-07-22 | C. R. Bard | System for the percutaneous transluminal front-end loading delivery and retrieval of a prosthetic occluder |
US5411481A (en) | 1992-04-08 | 1995-05-02 | American Cyanamid Co. | Surgical purse string suturing instrument and method |
US5236440A (en) | 1992-04-14 | 1993-08-17 | American Cyanamid Company | Surgical fastener |
US5354308A (en) | 1992-05-01 | 1994-10-11 | Beth Israel Hospital Association | Metal wire stent |
US5540712A (en) | 1992-05-01 | 1996-07-30 | Nitinol Medical Technologies, Inc. | Stent and method and apparatus for forming and delivering the same |
DE4215449C1 (en) | 1992-05-11 | 1993-09-02 | Ethicon Gmbh & Co Kg, 2000 Norderstedt, De | |
DE69328096T2 (en) | 1992-06-26 | 2000-09-14 | Schneider Usa Inc | CATHETER WITH EXTENDABLE MACHINE WIRE TIP |
US5312417A (en) * | 1992-07-29 | 1994-05-17 | Wilk Peter J | Laparoscopic cannula assembly and associated method |
US5312341A (en) | 1992-08-14 | 1994-05-17 | Wayne State University | Retaining apparatus and procedure for transseptal catheterization |
US5304184A (en) * | 1992-10-19 | 1994-04-19 | Indiana University Foundation | Apparatus and method for positive closure of an internal tissue membrane opening |
US5275826A (en) * | 1992-11-13 | 1994-01-04 | Purdue Research Foundation | Fluidized intestinal submucosa and its use as an injectable tissue graft |
US5357979A (en) | 1992-12-01 | 1994-10-25 | Intelliwire, Inc. | Flexible elongate device having a distal extremity with current controlled adjustable stiffness and adjustable bend location and method |
US5417699A (en) | 1992-12-10 | 1995-05-23 | Perclose Incorporated | Device and method for the percutaneous suturing of a vascular puncture site |
US5284488A (en) * | 1992-12-23 | 1994-02-08 | Sideris Eleftherios B | Adjustable devices for the occlusion of cardiac defects |
US6346074B1 (en) * | 1993-02-22 | 2002-02-12 | Heartport, Inc. | Devices for less invasive intracardiac interventions |
US5797960A (en) | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
US5312435A (en) | 1993-05-17 | 1994-05-17 | Kensey Nash Corporation | Fail predictable, reinforced anchor for hemostatic puncture closure |
US5480404A (en) * | 1993-06-16 | 1996-01-02 | Ethicon, Inc. | Surgical tissue retrieval instrument |
US5385156A (en) * | 1993-08-27 | 1995-01-31 | Rose Health Care Systems | Diagnostic and treatment method for cardiac rupture and apparatus for performing the same |
US5383899A (en) * | 1993-09-28 | 1995-01-24 | Hammerslag; Julius G. | Method of using a surface opening adhesive sealer |
US5571135A (en) * | 1993-10-22 | 1996-11-05 | Scimed Life Systems Inc. | Stent delivery apparatus and method |
US5480424A (en) * | 1993-11-01 | 1996-01-02 | Cox; James L. | Heart valve replacement using flexible tubes |
JP3185906B2 (en) * | 1993-11-26 | 2001-07-11 | ニプロ株式会社 | Prosthesis for atrial septal defect |
US6334872B1 (en) * | 1994-02-18 | 2002-01-01 | Organogenesis Inc. | Method for treating diseased or damaged organs |
US5545138A (en) | 1994-02-28 | 1996-08-13 | Medtronic, Inc. | Adjustable stiffness dilatation catheter |
JPH07265329A (en) * | 1994-03-31 | 1995-10-17 | Fuji Photo Optical Co Ltd | Puncture high frequency treatment device |
WO1995027448A1 (en) | 1994-04-06 | 1995-10-19 | William Cook Europe A/S | A medical article for implantation into the vascular system of a patient |
CA2188563C (en) | 1994-04-29 | 2005-08-02 | Andrew W. Buirge | Stent with collagen |
US6475232B1 (en) | 1996-12-10 | 2002-11-05 | Purdue Research Foundation | Stent with reduced thrombogenicity |
US5601571A (en) * | 1994-05-17 | 1997-02-11 | Moss; Gerald | Surgical fastener implantation device |
US5725552A (en) * | 1994-07-08 | 1998-03-10 | Aga Medical Corporation | Percutaneous catheter directed intravascular occlusion devices |
US5433727A (en) | 1994-08-16 | 1995-07-18 | Sideris; Eleftherios B. | Centering buttoned device for the occlusion of large defects for occluding |
US5573542A (en) | 1994-08-17 | 1996-11-12 | Tahoe Surgical Instruments-Puerto Rico | Endoscopic suture placement tool |
US5577299A (en) | 1994-08-26 | 1996-11-26 | Thompson; Carl W. | Quick-release mechanical knot apparatus |
US5618311A (en) * | 1994-09-28 | 1997-04-08 | Gryskiewicz; Joseph M. | Surgical subcuticular fastener system |
US5879366A (en) * | 1996-12-20 | 1999-03-09 | W.L. Gore & Associates, Inc. | Self-expanding defect closure device and method of making and using |
US6171329B1 (en) * | 1994-12-19 | 2001-01-09 | Gore Enterprise Holdings, Inc. | Self-expanding defect closure device and method of making and using |
US5702421A (en) | 1995-01-11 | 1997-12-30 | Schneidt; Bernhard | Closure device for closing a vascular opening, such as patent ductus arteriosus |
US5634936A (en) | 1995-02-06 | 1997-06-03 | Scimed Life Systems, Inc. | Device for closing a septal defect |
US5733337A (en) * | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
US5711969A (en) | 1995-04-07 | 1998-01-27 | Purdue Research Foundation | Large area submucosal tissue graft constructs |
CA2218072A1 (en) * | 1995-04-14 | 1996-10-17 | Schneider (Usa) Inc. | Rolling membrane stent delivery device |
US6322548B1 (en) | 1995-05-10 | 2001-11-27 | Eclipse Surgical Technologies | Delivery catheter system for heart chamber |
US6132438A (en) * | 1995-06-07 | 2000-10-17 | Ep Technologies, Inc. | Devices for installing stasis reducing means in body tissue |
ATE275880T1 (en) * | 1995-10-13 | 2004-10-15 | Transvascular Inc | DEVICE FOR BYPASSING ARTERIAL Narrowings AND/OR FOR PERFORMING OTHER TRANSVASCULAR PROCEDURES |
WO1997016119A1 (en) * | 1995-10-30 | 1997-05-09 | Children's Medical Center Corporation | Self-centering umbrella-type septal closure device |
US5868753A (en) * | 1995-11-13 | 1999-02-09 | Schatz; Richard A. | Stent retrieval catheter |
DE19604817C2 (en) * | 1996-02-09 | 2003-06-12 | Pfm Prod Fuer Die Med Ag | Device for closing defect openings in the human or animal body |
US5733294A (en) * | 1996-02-28 | 1998-03-31 | B. Braun Medical, Inc. | Self expanding cardiovascular occlusion device, method of using and method of making the same |
US5853422A (en) | 1996-03-22 | 1998-12-29 | Scimed Life Systems, Inc. | Apparatus and method for closing a septal defect |
US5755791A (en) | 1996-04-05 | 1998-05-26 | Purdue Research Foundation | Perforated submucosal tissue graft constructs |
AR001590A1 (en) * | 1996-04-10 | 1997-11-26 | Jorge Alberto Baccaro | Abnormal vascular communications occluder device and applicator cartridge of said device |
US5948427A (en) | 1996-04-25 | 1999-09-07 | Point Medical Corporation | Microparticulate surgical adhesive |
US6096053A (en) | 1996-05-03 | 2000-08-01 | Scimed Life Systems, Inc. | Medical retrieval basket |
US6488706B1 (en) | 1996-05-08 | 2002-12-03 | Carag Ag | Device for plugging an opening such as in a wall of a hollow or tubular organ |
WO1997041778A1 (en) | 1996-05-08 | 1997-11-13 | Salviac Limited | An occluder device |
US6143037A (en) | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
US5893856A (en) * | 1996-06-12 | 1999-04-13 | Mitek Surgical Products, Inc. | Apparatus and method for binding a first layer of material to a second layer of material |
NL1003497C2 (en) | 1996-07-03 | 1998-01-07 | Cordis Europ | Catheter with temporary vena-cava filter. |
CA2211249C (en) * | 1996-07-24 | 2007-07-17 | Cordis Corporation | Balloon catheter and methods of use |
US6066158A (en) | 1996-07-25 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot encasing and removal wire |
US5800516A (en) | 1996-08-08 | 1998-09-01 | Cordis Corporation | Deployable and retrievable shape memory stent/tube and method |
US6482224B1 (en) | 1996-08-22 | 2002-11-19 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US5741297A (en) * | 1996-08-28 | 1998-04-21 | Simon; Morris | Daisy occluder and method for septal defect repair |
US5810884A (en) | 1996-09-09 | 1998-09-22 | Beth Israel Deaconess Medical Center | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject |
US6086610A (en) | 1996-10-22 | 2000-07-11 | Nitinol Devices & Components | Composite self expanding stent device having a restraining element |
US5861003A (en) * | 1996-10-23 | 1999-01-19 | The Cleveland Clinic Foundation | Apparatus and method for occluding a defect or aperture within body surface |
JP2001503299A (en) | 1996-11-05 | 2001-03-13 | チャレンジ バイオプロダクツ カンパニー,リミテッド | Chemical modification of biomedical materials with genipin |
US6096347A (en) | 1996-11-05 | 2000-08-01 | Purdue Research Foundation | Myocardial graft constructs |
US6315791B1 (en) | 1996-12-03 | 2001-11-13 | Atrium Medical Corporation | Self-expanding prothesis |
NL1004721C2 (en) * | 1996-12-06 | 1998-06-09 | Ideamed N V | Ventilation equipment. |
WO1998025543A1 (en) * | 1996-12-10 | 1998-06-18 | Purdue Research Foundation | Tubular submucosal graft constructs |
EP1014895B1 (en) | 1996-12-10 | 2006-03-08 | Purdue Research Foundation | Artificial vascular valves |
US5807384A (en) | 1996-12-20 | 1998-09-15 | Eclipse Surgical Technologies, Inc. | Transmyocardial revascularization (TMR) enhanced treatment for coronary artery disease |
US5776162A (en) | 1997-01-03 | 1998-07-07 | Nitinol Medical Technologies, Inc. | Vessel implantable shape memory appliance with superelastic hinged joint |
JP3134288B2 (en) | 1997-01-30 | 2001-02-13 | 株式会社ニッショー | Endocardial suture surgery tool |
JP3134287B2 (en) | 1997-01-30 | 2001-02-13 | 株式会社ニッショー | Catheter assembly for endocardial suture surgery |
US5810867A (en) * | 1997-04-28 | 1998-09-22 | Medtronic, Inc. | Dilatation catheter with varied stiffness |
US5993844A (en) | 1997-05-08 | 1999-11-30 | Organogenesis, Inc. | Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix |
US6071292A (en) | 1997-06-28 | 2000-06-06 | Transvascular, Inc. | Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures |
US5997556A (en) | 1997-06-30 | 1999-12-07 | Eva Corporation | Surgical fastener |
US6030007A (en) * | 1997-07-07 | 2000-02-29 | Hughes Electronics Corporation | Continually adjustable nonreturn knot |
US6174322B1 (en) * | 1997-08-08 | 2001-01-16 | Cardia, Inc. | Occlusion device for the closure of a physical anomaly such as a vascular aperture or an aperture in a septum |
US5902319A (en) | 1997-09-25 | 1999-05-11 | Daley; Robert J. | Bioabsorbable staples |
US5895404A (en) * | 1997-09-29 | 1999-04-20 | Ruiz; Carlos E. | Apparatus and methods for percutaneously forming a passageway between adjacent vessels or portions of a vessel |
US6042606A (en) | 1997-09-29 | 2000-03-28 | Cook Incorporated | Radially expandable non-axially contracting surgical stent |
US6106913A (en) | 1997-10-10 | 2000-08-22 | Quantum Group, Inc | Fibrous structures containing nanofibrils and other textile fibers |
US5989268A (en) | 1997-10-28 | 1999-11-23 | Boston Scientific Corporation | Endoscopic hemostatic clipping device |
US5976174A (en) | 1997-12-15 | 1999-11-02 | Ruiz; Carlos E. | Medical hole closure device and methods of use |
US6129755A (en) | 1998-01-09 | 2000-10-10 | Nitinol Development Corporation | Intravascular stent having an improved strut configuration |
US5944738A (en) | 1998-02-06 | 1999-08-31 | Aga Medical Corporation | Percutaneous catheter directed constricting occlusion device |
JP2002502626A (en) * | 1998-02-10 | 2002-01-29 | アーテミス・メディカル・インコーポレイテッド | Supplementary device and method of using the same |
JP3799810B2 (en) * | 1998-03-30 | 2006-07-19 | ニプロ株式会社 | Transcatheter surgery closure plug and catheter assembly |
JP3733580B2 (en) | 1998-04-06 | 2006-01-11 | ニプロ株式会社 | Closure collection tool for defect closure |
US5993475A (en) | 1998-04-22 | 1999-11-30 | Bristol-Myers Squibb Co. | Tissue repair device |
US6113609A (en) | 1998-05-26 | 2000-09-05 | Scimed Life Systems, Inc. | Implantable tissue fastener and system for treating gastroesophageal reflux disease |
US7452371B2 (en) | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US6265333B1 (en) | 1998-06-02 | 2001-07-24 | Board Of Regents, University Of Nebraska-Lincoln | Delamination resistant composites prepared by small diameter fiber reinforcement at ply interfaces |
US6740101B2 (en) * | 1998-06-10 | 2004-05-25 | Converge Medical, Inc. | Sutureless anastomosis systems |
US6328822B1 (en) * | 1998-06-26 | 2001-12-11 | Kiyohito Ishida | Functionally graded alloy, use thereof and method for producing same |
US6369039B1 (en) * | 1998-06-30 | 2002-04-09 | Scimed Life Sytems, Inc. | High efficiency local drug delivery |
US6165183A (en) | 1998-07-15 | 2000-12-26 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
US6149664A (en) | 1998-08-27 | 2000-11-21 | Micrus Corporation | Shape memory pusher introducer for vasoocclusive devices |
US6007558A (en) | 1998-09-25 | 1999-12-28 | Nitinol Medical Technologies, Inc. | Removable embolus blood clot filter |
US6030406A (en) * | 1998-10-05 | 2000-02-29 | Origin Medsystems, Inc. | Method and apparatus for tissue dissection |
US5919200A (en) | 1998-10-09 | 1999-07-06 | Hearten Medical, Inc. | Balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter |
US7044134B2 (en) | 1999-11-08 | 2006-05-16 | Ev3 Sunnyvale, Inc | Method of implanting a device in the left atrial appendage |
US6152144A (en) | 1998-11-06 | 2000-11-28 | Appriva Medical, Inc. | Method and device for left atrial appendage occlusion |
US7713282B2 (en) * | 1998-11-06 | 2010-05-11 | Atritech, Inc. | Detachable atrial appendage occlusion balloon |
US6482210B1 (en) | 1998-11-12 | 2002-11-19 | Orthopaedic Biosystems, Ltd., Inc. | Soft tissue/ligament to bone fixation device with inserter |
JP3906475B2 (en) * | 1998-12-22 | 2007-04-18 | ニプロ株式会社 | Transcatheter surgery closure plug and catheter assembly |
US6228097B1 (en) | 1999-01-22 | 2001-05-08 | Scion International, Inc. | Surgical instrument for clipping and cutting blood vessels and organic structures |
US6217590B1 (en) * | 1999-01-22 | 2001-04-17 | Scion International, Inc. | Surgical instrument for applying multiple staples and cutting blood vessels and organic structures and method therefor |
DE60042316D1 (en) * | 1999-01-28 | 2009-07-16 | Salviac Ltd | CATHETER WITH EXPANDABLE END CUT |
US6156055A (en) * | 1999-03-23 | 2000-12-05 | Nitinol Medical Technologies Inc. | Gripping device for implanting, repositioning or extracting an object within a body vessel |
US6352531B1 (en) * | 1999-03-24 | 2002-03-05 | Micrus Corporation | Variable stiffness optical fiber shaft |
EP1040843B1 (en) * | 1999-03-29 | 2005-09-28 | William Cook Europe A/S | A guidewire |
US6277138B1 (en) | 1999-08-17 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame |
US6379342B1 (en) * | 1999-04-02 | 2002-04-30 | Scion International, Inc. | Ampoule for dispensing medication and method of use |
JP2000300571A (en) * | 1999-04-19 | 2000-10-31 | Nissho Corp | Closure plug for transcatheter operation |
US6206907B1 (en) * | 1999-05-07 | 2001-03-27 | Cardia, Inc. | Occlusion device with stranded wire support arms |
US6379368B1 (en) * | 1999-05-13 | 2002-04-30 | Cardia, Inc. | Occlusion device with non-thrombogenic properties |
US6712836B1 (en) * | 1999-05-13 | 2004-03-30 | St. Jude Medical Atg, Inc. | Apparatus and methods for closing septal defects and occluding blood flow |
US6488689B1 (en) | 1999-05-20 | 2002-12-03 | Aaron V. Kaplan | Methods and apparatus for transpericardial left atrial appendage closure |
US6165204A (en) | 1999-06-11 | 2000-12-26 | Scion International, Inc. | Shaped suture clip, appliance and method therefor |
US6494888B1 (en) | 1999-06-22 | 2002-12-17 | Ndo Surgical, Inc. | Tissue reconfiguration |
US6306424B1 (en) | 1999-06-30 | 2001-10-23 | Ethicon, Inc. | Foam composite for the repair or regeneration of tissue |
US6245080B1 (en) | 1999-07-13 | 2001-06-12 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US6206895B1 (en) * | 1999-07-13 | 2001-03-27 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US6398796B2 (en) | 1999-07-13 | 2002-06-04 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US6179859B1 (en) * | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
US6213976B1 (en) * | 1999-07-22 | 2001-04-10 | Advanced Research And Technology Institute, Inc. | Brachytherapy guide catheter |
US7892246B2 (en) | 1999-07-28 | 2011-02-22 | Bioconnect Systems, Inc. | Devices and methods for interconnecting conduits and closing openings in tissue |
US6168579B1 (en) * | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
US6187016B1 (en) * | 1999-09-14 | 2001-02-13 | Daniel G. Hedges | Stent retrieval device |
US6231561B1 (en) | 1999-09-20 | 2001-05-15 | Appriva Medical, Inc. | Method and apparatus for closing a body lumen |
US6551303B1 (en) | 1999-10-27 | 2003-04-22 | Atritech, Inc. | Barrier device for ostium of left atrial appendage |
US6387104B1 (en) | 1999-11-12 | 2002-05-14 | Scimed Life Systems, Inc. | Method and apparatus for endoscopic repair of the lower esophageal sphincter |
US6371971B1 (en) * | 1999-11-15 | 2002-04-16 | Scimed Life Systems, Inc. | Guidewire filter and methods of use |
US7335426B2 (en) * | 1999-11-19 | 2008-02-26 | Advanced Bio Prosthetic Surfaces, Ltd. | High strength vacuum deposited nitinol alloy films and method of making same |
US20010041914A1 (en) | 1999-11-22 | 2001-11-15 | Frazier Andrew G.C. | Tissue patch deployment catheter |
US6790218B2 (en) * | 1999-12-23 | 2004-09-14 | Swaminathan Jayaraman | Occlusive coil manufacture and delivery |
US6780197B2 (en) * | 2000-01-05 | 2004-08-24 | Integrated Vascular Systems, Inc. | Apparatus and methods for delivering a vascular closure device to a body lumen |
US6391048B1 (en) | 2000-01-05 | 2002-05-21 | Integrated Vascular Systems, Inc. | Integrated vascular device with puncture site closure component and sealant and methods of use |
US6517550B1 (en) * | 2000-02-02 | 2003-02-11 | Board Of Regents, The University Of Texas System | Foreign body retrieval device |
US6537198B1 (en) * | 2000-03-21 | 2003-03-25 | Myocor, Inc. | Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly |
US7056294B2 (en) | 2000-04-13 | 2006-06-06 | Ev3 Sunnyvale, Inc | Method and apparatus for accessing the left atrial appendage |
JP3844661B2 (en) * | 2000-04-19 | 2006-11-15 | ラディ・メディカル・システムズ・アクチェボラーグ | Intra-arterial embolus |
US6551344B2 (en) | 2000-04-26 | 2003-04-22 | Ev3 Inc. | Septal defect occluder |
US6214029B1 (en) * | 2000-04-26 | 2001-04-10 | Microvena Corporation | Septal defect occluder |
US6352552B1 (en) * | 2000-05-02 | 2002-03-05 | Scion Cardio-Vascular, Inc. | Stent |
US6334864B1 (en) | 2000-05-17 | 2002-01-01 | Aga Medical Corp. | Alignment member for delivering a non-symmetric device with a predefined orientation |
US6440152B1 (en) | 2000-07-28 | 2002-08-27 | Microvena Corporation | Defect occluder release assembly and method |
WO2002017797A1 (en) * | 2000-09-01 | 2002-03-07 | Advanced Vascular Technologies, Llc | Endovascular fastener and grafting apparatus and method |
US6364853B1 (en) * | 2000-09-11 | 2002-04-02 | Scion International, Inc. | Irrigation and suction valve and method therefor |
AU2001291201A1 (en) * | 2000-09-21 | 2002-04-02 | Atritech, Inc. | Apparatus for implanting devices in atrial appendages |
CA2423061A1 (en) | 2000-09-25 | 2002-03-28 | Cohesion Technologies, Inc. | Resorbable anastomosis stents and plugs |
US6666861B1 (en) | 2000-10-05 | 2003-12-23 | James R. Grabek | Atrial appendage remodeling device and method |
US6375625B1 (en) * | 2000-10-18 | 2002-04-23 | Scion Valley, Inc. | In-line specimen trap and method therefor |
EP1326672A4 (en) * | 2000-10-18 | 2007-03-07 | Nmt Medical Inc | Over-the-wire interlock attachment/detachment mechanism |
US6746404B2 (en) | 2000-12-18 | 2004-06-08 | Biosense, Inc. | Method for anchoring a medical device between tissue |
US20020084178A1 (en) | 2000-12-19 | 2002-07-04 | Nicast Corporation Ltd. | Method and apparatus for manufacturing polymer fiber shells via electrospinning |
US6569181B1 (en) * | 2000-12-20 | 2003-05-27 | Advanced Cardiovascular Systems, Inc. | Stent retrieval system |
US20020128680A1 (en) | 2001-01-25 | 2002-09-12 | Pavlovic Jennifer L. | Distal protection device with electrospun polymer fiber matrix |
US6550480B2 (en) | 2001-01-31 | 2003-04-22 | Numed/Tech Llc | Lumen occluders made from thermodynamic materials |
US20020107531A1 (en) | 2001-02-06 | 2002-08-08 | Schreck Stefan G. | Method and system for tissue repair using dual catheters |
US6623518B2 (en) | 2001-02-26 | 2003-09-23 | Ev3 Peripheral, Inc. | Implant delivery system with interlock |
US6726696B1 (en) | 2001-04-24 | 2004-04-27 | Advanced Catheter Engineering, Inc. | Patches and collars for medical applications and methods of use |
US6837901B2 (en) * | 2001-04-27 | 2005-01-04 | Intek Technology L.L.C. | Methods for delivering, repositioning and/or retrieving self-expanding stents |
US6537300B2 (en) | 2001-05-30 | 2003-03-25 | Scimed Life Systems, Inc. | Implantable obstruction device for septal defects |
US7338514B2 (en) | 2001-06-01 | 2008-03-04 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods and tools, and related methods of use |
JP2005508208A (en) | 2001-06-04 | 2005-03-31 | アルバート・アインシュタイン・ヘルスケア・ネットワーク | Cardiac stimulator with thrombus filter and atrial pacemaker |
US7288105B2 (en) * | 2001-08-01 | 2007-10-30 | Ev3 Endovascular, Inc. | Tissue opening occluder |
US6702835B2 (en) * | 2001-09-07 | 2004-03-09 | Core Medical, Inc. | Needle apparatus for closing septal defects and methods for using such apparatus |
US6776784B2 (en) * | 2001-09-06 | 2004-08-17 | Core Medical, Inc. | Clip apparatus for closing septal defects and methods of use |
US6596013B2 (en) | 2001-09-20 | 2003-07-22 | Scimed Life Systems, Inc. | Method and apparatus for treating septal defects |
US6893431B2 (en) | 2001-10-15 | 2005-05-17 | Scimed Life Systems, Inc. | Medical device for delivering patches |
US7153320B2 (en) * | 2001-12-13 | 2006-12-26 | Scimed Life Systems, Inc. | Hydraulic controlled retractable tip filter retrieval catheter |
EP1467661A4 (en) | 2001-12-19 | 2008-11-05 | Nmt Medical Inc | Septal occluder and associated methods |
US20030139819A1 (en) | 2002-01-18 | 2003-07-24 | Beer Nicholas De | Method and apparatus for closing septal defects |
US6866679B2 (en) * | 2002-03-12 | 2005-03-15 | Ev3 Inc. | Everting stent and stent delivery system |
US7976564B2 (en) | 2002-05-06 | 2011-07-12 | St. Jude Medical, Cardiology Division, Inc. | PFO closure devices and related methods of use |
US7115135B2 (en) | 2003-01-22 | 2006-10-03 | Cardia, Inc. | Occlusion device having five or more arms |
US8021359B2 (en) | 2003-02-13 | 2011-09-20 | Coaptus Medical Corporation | Transseptal closure of a patent foramen ovale and other cardiac defects |
US7658747B2 (en) | 2003-03-12 | 2010-02-09 | Nmt Medical, Inc. | Medical device for manipulation of a medical implant |
US7293562B2 (en) * | 2003-03-27 | 2007-11-13 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
US7186251B2 (en) | 2003-03-27 | 2007-03-06 | Cierra, Inc. | Energy based devices and methods for treatment of patent foramen ovale |
US6939348B2 (en) | 2003-03-27 | 2005-09-06 | Cierra, Inc. | Energy based devices and methods for treatment of patent foramen ovale |
AU2004226374B2 (en) | 2003-03-27 | 2009-11-12 | Terumo Kabushiki Kaisha | Methods and apparatus for treatment of patent foramen ovale |
US7165552B2 (en) * | 2003-03-27 | 2007-01-23 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
US7367975B2 (en) | 2004-06-21 | 2008-05-06 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
AU2006235506B2 (en) | 2005-04-11 | 2011-06-30 | Terumo Kabushiki Kaisha | Methods and apparatus to achieve a closure of a layered tissue defect |
-
2003
- 2003-03-12 US US10/386,828 patent/US7658747B2/en active Active
-
2004
- 2004-03-10 JP JP2006507032A patent/JP2006519657A/en not_active Withdrawn
- 2004-03-10 CA CA002518366A patent/CA2518366A1/en not_active Abandoned
- 2004-03-10 WO PCT/US2004/007288 patent/WO2004080289A2/en active Application Filing
- 2004-03-10 EP EP04719223A patent/EP1601315A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2006519657A (en) | 2006-08-31 |
US7658747B2 (en) | 2010-02-09 |
WO2004080289A3 (en) | 2005-02-10 |
EP1601315A2 (en) | 2005-12-07 |
WO2004080289A2 (en) | 2004-09-23 |
US20040181237A1 (en) | 2004-09-16 |
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