CA2530052A1 - System and method for analyte measurement using dose sufficiency electrodes - Google Patents
System and method for analyte measurement using dose sufficiency electrodes Download PDFInfo
- Publication number
- CA2530052A1 CA2530052A1 CA002530052A CA2530052A CA2530052A1 CA 2530052 A1 CA2530052 A1 CA 2530052A1 CA 002530052 A CA002530052 A CA 002530052A CA 2530052 A CA2530052 A CA 2530052A CA 2530052 A1 CA2530052 A1 CA 2530052A1
- Authority
- CA
- Canada
- Prior art keywords
- terminus
- test strip
- dose sufficiency
- biological fluid
- response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Abstract
A method of determining dose sufficiency related parameters in a test strip for performing a measurement on a biological fluid comprising: a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap there between and in operative with the capillary fill, chamber, the electrodes located between t he measurement zone and the terminus; applying the biological fluid to the opening, whereby the fluid flows from the opening towards the terminus; applying an AC test signal to a first one of the electrodes; determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone.
Claims (65)
1. A method of determining dose sufficiency in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and in operative communication with the capillary fill chamber, the electrodes located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and in operative communication with the capillary fill chamber, the electrodes located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
2. The method of claim 1, wherein the test signal is an AC signal.
3. The method of claim 1, wherein the response comprises magnitude and phase angle information.
4. The method of claim 1, wherein the response comprises an admittance value.
5. A method of determining dose sufficiency in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening, a fluid flow terminus, a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
providing a biological fluid test strip, comprising:
a fluid flow intake opening, a fluid flow terminus, a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
6. The method of claim 5, wherein the test signal is an AC signal.
7. The method of claim 5, wherein the response comprises magnitude and phase angle information.
8. The method of claim 5, wherein the response comprises an admittance value.
9. The method of claim 5, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
10. A method of determining a dose sufficiency in a test strip for performing a measurement on a biological fluid, comprising:
providing a biological fluid test strip comprising:
a capillary fill chamber extending a length along the test strip, at least two measurement electrodes in operative communication with the chamber, and at least two dose sufficiency electrodes in operative communication with the chamber;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
providing a biological fluid test strip comprising:
a capillary fill chamber extending a length along the test strip, at least two measurement electrodes in operative communication with the chamber, and at least two dose sufficiency electrodes in operative communication with the chamber;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
11. The method of claim 10, wherein the test signal is an AC signal.
12. The method of claim 10, wherein the response comprises magnitude and phase angle information.
13. The method of claim 10, wherein the response comprises an admittance value.
14. The method of claim 10 wherein the applying a dose sufficiency test signal results in the dose sufficiency electrodes exhibiting an edge effect.
15. The method of claim 10 wherein the AC component has a frequency of about kHz.
16. A method of determining a fill sufficiency in test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate the fill sufficiency of the biological fluid.
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate the fill sufficiency of the biological fluid.
17. The method of claim 16, wherein the test signal is an AC signal.
18. The method of claim 16, wherein the response comprises magnitude and phase angle information.
19. The method of claim 16, wherein the response comprises an admittance value.
20. A method of determining a dose sufficiency in a test strip for performing a measurement on a biological fluid, comprising:
providing a biological fluid test strip comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone; and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
providing a biological fluid test strip comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone; and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
21. The method of claim 20, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
22. The method of claim 20, wherein the test signal is an AC signal.
23. The method of claim 20, wherein the response comprises magnitude and phase angle information.
24. The method of claim 20, wherein the response comprises an admittance value.
25. The method of claim 20 wherein the applying a dose sufficiency test signal results in the dose sufficiency electrodes exhibiting an edge effect.
26. The method of claim 20 wherein the AC component has a frequency of about kHz.
27. A method of determining a fill sufficiency in test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate a volume sufficiency of the biological fluid.
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate a volume sufficiency of the biological fluid.
28. The method of claim 27, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
29. The method of claim 27, wherein the test signal is an AC signal.
30. The method of claim 27, wherein the response comprises magnitude and phase angle information.
31. The method of claim 27, wherein the response comprises an admittance value.
32. A method of determining dosage fill level in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a response to the signal at the other of the dose sufficiency electrodes;
determining the dosage fill level based upon the response.
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a response to the signal at the other of the dose sufficiency electrodes;
determining the dosage fill level based upon the response.
33. The method of claim 32, wherein the test signal is an AC signal.
34. The method of claim 32, wherein the response comprises magnitude and phase angle information.
35. The method of claim 32, wherein the response comprises an admittance value.
36. The method of claim 32, wherein the response varies in correlation with the degree to which the biological fluid bridges the gap.
37. A method of determining a fill level of a biological fluid in a test strip for performing a measurement on the fluid comprising:
providing a test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the test signal at the other of the dose sufficiency electrodes;
determining the fill level of the biological fluid based upon the response wherein the response varies in relation to the fill level.
providing a test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the test signal at the other of the dose sufficiency electrodes;
determining the fill level of the biological fluid based upon the response wherein the response varies in relation to the fill level.
38. The method of claim 37, wherein the test signal is an AC signal.
39. The method of claim 37, wherein the response comprises magnitude and phase angle information.
40. The method of claim 37, wherein the response comprises an admittance value.
41. A method of determining dosage fill level in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two pairs of dose sufficiency electrodes in operative communication with the chamber, each of the pairs of dose sufficiency electrodes positioned to define a respective gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs;
measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the dosage fill level based upon the responses.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two pairs of dose sufficiency electrodes in operative communication with the chamber, each of the pairs of dose sufficiency electrodes positioned to define a respective gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs;
measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the dosage fill level based upon the responses.
42. The method of claim 41, wherein the test signal is an AC signal.
43. The method of claim 41, wherein the response comprises magnitude and phase angle information.
44. The method of claim 41, wherein the response comprises an admittance value.
45. A method of determining a fill level of a biological fluid in a test strip for performing a measurement on the fluid comprising:
providing a test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening to the terminus; and at least two pairs of dose sufficiency electrodes positioned between the reagent and the terminus, each of the pairs of dose sufficiency electrodes defining a respective gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs; and measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the fill level of the biological fluid based upon the responses.
providing a test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening to the terminus; and at least two pairs of dose sufficiency electrodes positioned between the reagent and the terminus, each of the pairs of dose sufficiency electrodes defining a respective gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs; and measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the fill level of the biological fluid based upon the responses.
46. The method of claim 45, wherein the test signal is an AC signal.
47. The method of claim 45, wherein the response comprises magnitude and phase angle information.
48. The method of claim 45, wherein the response comprises an admittance value.
49. A method of determining dosage fill rate in a biological fluid test strip comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
50. The method of claim 49, wherein the test signal is an AC signal.
51. The method of claim 49, wherein the response comprises magnitude and phase angle information.
52. The method of claim 49, wherein the response comprises an admittance value.
53. The method of claim 49 further comprising recording the first response and the second response.
54. A method of determining dosage fill rate in a biological fluid test strip comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned between the opening and the terminus, and at least two dose sufficiency electrodes positioned between the measurement zone and the terminus, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to flow from the opening toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned between the opening and the terminus, and at least two dose sufficiency electrodes positioned between the measurement zone and the terminus, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to flow from the opening toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
55. The method of claim 54, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
56. The method of claim 55, wherein the test signal is an AC signal.
57. The method of claim 55, wherein the response comprises magnitude and phase angle information.
58. The method of claim 55, wherein the response comprises an admittance value.
59. The method of claim 55 further comprising recording the first response and the second response.
60. A test strip for performing a measurement on a biological fluid comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the chamber; and at least two dose sufficiency electrodes in operative communication with the chamber;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the capillary chamber and second edges substantially perpendicular to the length of the capillary fill chamber with the first edges being of greater length than the second edges.
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the chamber; and at least two dose sufficiency electrodes in operative communication with the chamber;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the capillary chamber and second edges substantially perpendicular to the length of the capillary fill chamber with the first edges being of greater length than the second edges.
61. A test strip for performing a measurement on a biological fluid, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the capillary chamber and a second axis substantially perpendicular to the length of the capillary fill chamber with the first axis being of greater length than the second axis.
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the capillary chamber and a second axis substantially perpendicular to the length of the capillary fill chamber with the first axis being of greater length than the second axis.
62. A test strip for performing a measurement on a biological fluid comprising:
a fluid flow path extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the fluid flow path; and at least two dose sufficiency electrodes in operative communication with the fluid flow path;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the fluid flow path and second edges substantially perpendicular to the length of the fluid flow path with the first edges being of greater length than the second edges.
a fluid flow path extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the fluid flow path; and at least two dose sufficiency electrodes in operative communication with the fluid flow path;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the fluid flow path and second edges substantially perpendicular to the length of the fluid flow path with the first edges being of greater length than the second edges.
63. The method of claim 62, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
64. A test strip for performing a measurement on a biological fluid, comprising:
a fluid flow path extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the fluid flow path, the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the fluid flow path and a second axis substantially perpendicular to the length of the fluid flow path with the first axis being of greater length than the second axis.
a fluid flow path extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the fluid flow path, the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the fluid flow path and a second axis substantially perpendicular to the length of the fluid flow path with the first axis being of greater length than the second axis.
65. The method of claim 64, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2714309A CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48029803P | 2003-06-20 | 2003-06-20 | |
US60/480,298 | 2003-06-20 | ||
US10/687,958 | 2003-10-17 | ||
US10/687,958 US7452457B2 (en) | 2003-06-20 | 2003-10-17 | System and method for analyte measurement using dose sufficiency electrodes |
PCT/US2004/019721 WO2005008231A1 (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement of biological fluids using dose sufficiency electrodes |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2714309A Division CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2530052A1 true CA2530052A1 (en) | 2005-01-27 |
CA2530052C CA2530052C (en) | 2010-11-30 |
Family
ID=33519465
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2714309A Active CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
CA2530052A Active CA2530052C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
CA2814802A Active CA2814802C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2714309A Active CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2814802A Active CA2814802C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
Country Status (5)
Country | Link |
---|---|
US (2) | US7452457B2 (en) |
EP (1) | EP1639355B1 (en) |
JP (1) | JP4681546B2 (en) |
CA (3) | CA2714309C (en) |
WO (1) | WO2005008231A1 (en) |
Families Citing this family (136)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US7682318B2 (en) | 2001-06-12 | 2010-03-23 | Pelikan Technologies, Inc. | Blood sampling apparatus and method |
ATE485766T1 (en) | 2001-06-12 | 2010-11-15 | Pelikan Technologies Inc | ELECTRICAL ACTUATING ELEMENT FOR A LANCET |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
US7749174B2 (en) | 2001-06-12 | 2010-07-06 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
DE60234598D1 (en) | 2001-06-12 | 2010-01-14 | Pelikan Technologies Inc | SELF-OPTIMIZING LANZET DEVICE WITH ADAPTANT FOR TEMPORAL FLUCTUATIONS OF SKIN PROPERTIES |
EP1404234B1 (en) | 2001-06-12 | 2011-02-09 | Pelikan Technologies Inc. | Apparatus for improving success rate of blood yield from a fingerstick |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7226461B2 (en) | 2002-04-19 | 2007-06-05 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US7892185B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
EP1628567B1 (en) | 2003-05-30 | 2010-08-04 | Pelikan Technologies Inc. | Method and apparatus for fluid injection |
DK1633235T3 (en) | 2003-06-06 | 2014-08-18 | Sanofi Aventis Deutschland | Apparatus for sampling body fluid and detecting analyte |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
US20070264721A1 (en) * | 2003-10-17 | 2007-11-15 | Buck Harvey B | System and method for analyte measurement using a nonlinear sample response |
ES2657627T3 (en) * | 2003-06-20 | 2018-03-06 | F. Hoffmann-La Roche Ag | Electrochemical biosensors |
US8148164B2 (en) | 2003-06-20 | 2012-04-03 | Roche Diagnostics Operations, Inc. | System and method for determining the concentration of an analyte in a sample fluid |
US7452457B2 (en) * | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
PT1639352T (en) | 2003-06-20 | 2018-07-09 | Hoffmann La Roche | Method and reagent for producing narrow, homogenous reagent strips |
US8282576B2 (en) | 2003-09-29 | 2012-10-09 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for an improved sample capture device |
EP1680014A4 (en) | 2003-10-14 | 2009-01-21 | Pelikan Technologies Inc | Method and apparatus for a variable user interface |
US8007656B2 (en) * | 2003-10-24 | 2011-08-30 | Bayer Healthcare Llc | Enzymatic electrochemical biosensor |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
EP1706026B1 (en) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Method and apparatus for improving fluidic flow and sample capture |
EP1713926B1 (en) | 2004-02-06 | 2012-08-01 | Bayer HealthCare, LLC | Oxidizable species as an internal reference for biosensors and method of use |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
EP1765194A4 (en) | 2004-06-03 | 2010-09-29 | Pelikan Technologies Inc | Method and apparatus for a fluid sampling device |
US7556723B2 (en) * | 2004-06-18 | 2009-07-07 | Roche Diagnostics Operations, Inc. | Electrode design for biosensor |
DE112005001154B4 (en) * | 2004-06-23 | 2011-09-29 | Tesa Se | Medical biosensor used to examine biological fluids |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
KR101321296B1 (en) | 2005-07-20 | 2013-10-28 | 바이엘 헬스케어 엘엘씨 | Gated amperometry temperature determination |
JP5671205B2 (en) | 2005-09-30 | 2015-02-18 | バイエル・ヘルスケア・エルエルシー | Gated voltammetry |
CA2807519C (en) * | 2005-11-14 | 2016-01-12 | Bayer Healthcare Llc | Test sensor reagent having cellulose polymers |
EP1813937A1 (en) * | 2006-01-25 | 2007-08-01 | Roche Diagnostics GmbH | Electrochemical biosensor analysis system |
WO2007100651A1 (en) * | 2006-02-27 | 2007-09-07 | Bayer Healthcare Llc | Temperature-adjusted analyte determination for biosensor systems |
US7887682B2 (en) | 2006-03-29 | 2011-02-15 | Abbott Diabetes Care Inc. | Analyte sensors and methods of use |
US8529751B2 (en) | 2006-03-31 | 2013-09-10 | Lifescan, Inc. | Systems and methods for discriminating control solution from a physiological sample |
US8398443B2 (en) * | 2006-04-21 | 2013-03-19 | Roche Diagnostics Operations, Inc. | Biological testing system and connector therefor |
US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
US7312042B1 (en) | 2006-10-24 | 2007-12-25 | Abbott Diabetes Care, Inc. | Embossed cell analyte sensor and methods of manufacture |
ES2825036T3 (en) | 2006-10-24 | 2021-05-14 | Ascensia Diabetes Care Holdings Ag | Transient decay amperometry |
US20100066356A1 (en) * | 2006-12-15 | 2010-03-18 | Koninklijke Philips Electronics N.V. | Sensor device comprising means for determining the sample covered area of the sensitive surface |
US8409424B2 (en) * | 2006-12-19 | 2013-04-02 | Apex Biotechnology Corp. | Electrochemical test strip, electrochemical test system, and measurement method using the same |
ES2693097T3 (en) | 2007-05-30 | 2018-12-07 | Ascensia Diabetes Care Holdings Ag | System and method for managing health data |
JP4856009B2 (en) * | 2007-05-31 | 2012-01-18 | グンゼ株式会社 | Biosensor |
JP4856011B2 (en) * | 2007-06-05 | 2012-01-18 | グンゼ株式会社 | Biosensor |
US8778168B2 (en) | 2007-09-28 | 2014-07-15 | Lifescan, Inc. | Systems and methods of discriminating control solution from a physiological sample |
JPWO2009057793A1 (en) * | 2007-10-31 | 2011-03-17 | アークレイ株式会社 | Analysis tool, analyzer, sample shortage detection method and sample analysis method |
WO2009076302A1 (en) | 2007-12-10 | 2009-06-18 | Bayer Healthcare Llc | Control markers for auto-detection of control solution and methods of use |
CA2708038A1 (en) * | 2007-12-10 | 2009-09-03 | Bayer Healthcare Llc | Slope-based compensation |
AU2015203087B2 (en) * | 2008-01-17 | 2017-03-16 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
AU2013202708B2 (en) * | 2008-01-17 | 2014-08-21 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8603768B2 (en) | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8431011B2 (en) * | 2008-01-31 | 2013-04-30 | Abbott Diabetes Care Inc. | Method for automatically and rapidly distinguishing between control and sample solutions in a biosensor strip |
JP2009250806A (en) * | 2008-04-07 | 2009-10-29 | Panasonic Corp | Biosensor system, sensor chip and measuring method of concentration of analyte in blood sample |
WO2009126900A1 (en) | 2008-04-11 | 2009-10-15 | Pelikan Technologies, Inc. | Method and apparatus for analyte detecting device |
US8551320B2 (en) * | 2008-06-09 | 2013-10-08 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
AU2012201915C1 (en) * | 2008-06-09 | 2014-09-25 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
CN102227636A (en) * | 2008-09-30 | 2011-10-26 | 梅纳伊医疗科技有限公司 | Sample measurement system |
WO2010040090A2 (en) * | 2008-10-03 | 2010-04-08 | Bayer Healthcare Llc | System and method for predicting ambient temperature in a fluid analyte meter |
BRPI0923342A2 (en) | 2008-12-08 | 2016-01-12 | Bayer Healthcare Llc | biosensor system with signal adjustment |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
WO2010151592A1 (en) | 2009-06-23 | 2010-12-29 | Bayer Healthcare Llc | System and apparatus for determining temperatures in a fluid analyte system |
US20110048972A1 (en) * | 2009-08-31 | 2011-03-03 | Lifescan Scotland Limited | Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration |
JP5782044B2 (en) | 2009-11-10 | 2015-09-24 | バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC | Underfill amount recognition system for biosensors |
US8877034B2 (en) | 2009-12-30 | 2014-11-04 | Lifescan, Inc. | Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity |
US8101065B2 (en) | 2009-12-30 | 2012-01-24 | Lifescan, Inc. | Systems, devices, and methods for improving accuracy of biosensors using fill time |
US20110168575A1 (en) * | 2010-01-08 | 2011-07-14 | Roche Diaagnostics Operations, Inc. | Sample characterization based on ac measurement methods |
US20110208435A1 (en) * | 2010-02-25 | 2011-08-25 | Lifescan Scotland Ltd. | Capacitance detection in electrochemical assays |
MX2012010860A (en) * | 2010-03-22 | 2013-03-05 | Bayer Healthcare Llc | Residual compensation for a biosensor. |
GB201005357D0 (en) | 2010-03-30 | 2010-05-12 | Menai Medical Technologies Ltd | Sampling plate |
GB201005359D0 (en) | 2010-03-30 | 2010-05-12 | Menai Medical Technologies Ltd | Sampling plate |
US8123572B2 (en) | 2010-04-02 | 2012-02-28 | Tyco Electronics Corporation | Electrical components having a contact configured to engage a via of a circuit board |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
CA2798938C (en) | 2010-06-07 | 2018-08-07 | Bayer Healthcare Llc | Slope-based compensation including secondary output signals |
KR101929058B1 (en) | 2010-06-07 | 2018-12-13 | 바이엘 헬쓰케어 엘엘씨 | Underfill management system for a biosensor |
PL2596115T3 (en) | 2010-07-23 | 2016-09-30 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | |
US8603323B2 (en) * | 2010-09-20 | 2013-12-10 | Lifescan, Inc. | Apparatus and process for improved measurements of a monitoring device |
US8932445B2 (en) | 2010-09-30 | 2015-01-13 | Cilag Gmbh International | Systems and methods for improved stability of electrochemical sensors |
US8617370B2 (en) | 2010-09-30 | 2013-12-31 | Cilag Gmbh International | Systems and methods of discriminating between a control sample and a test fluid using capacitance |
EP2679992B1 (en) * | 2011-02-23 | 2019-10-23 | PHC Holdings Corporation | Biological sample measuring system |
US9775806B2 (en) | 2011-09-21 | 2017-10-03 | Ascensia Diabetes Care Holdings Ag | Analysis compensation including segmented signals |
US9903830B2 (en) * | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
GB2501870B (en) | 2012-04-13 | 2018-07-18 | Smartcare Tech Limited | Improvements in and relating to sample measurement |
KR101466222B1 (en) * | 2012-06-01 | 2014-12-01 | 주식회사 아이센스 | Electrochemical biosensor with improved accuracy |
TWI513978B (en) * | 2012-06-08 | 2015-12-21 | Hmd Biomedical Inc | Test strip, detecting device and detection method |
MX355854B (en) * | 2012-07-27 | 2018-05-03 | Ascensia Diabetes Care Holdings Ag | System and method for detecting used and dried sensors. |
PL2972268T3 (en) * | 2013-03-15 | 2017-10-31 | Hoffmann La Roche | Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same |
EP2972260B1 (en) * | 2013-03-15 | 2018-07-11 | Roche Diabetes Care GmbH | Methods of scaling data used to construct biosensor algorithms |
WO2014140177A2 (en) | 2013-03-15 | 2014-09-18 | Roche Diagnostics Gmbh | Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom as well as devices, apparatuses and systems incorporting the same |
JP6352954B2 (en) | 2013-03-15 | 2018-07-04 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Method and device for using information from recovery pulses in electrochemical analyte measurement, apparatus and system incorporating them |
EP3008454B1 (en) * | 2013-06-10 | 2024-03-27 | Roche Diagnostics GmbH | Method and system for detecting an analyte in a body fluid |
CN104345079A (en) * | 2013-08-02 | 2015-02-11 | 达尔生技股份有限公司 | Determination methods |
US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
JP5702457B2 (en) * | 2013-12-06 | 2015-04-15 | パナソニックヘルスケアホールディングス株式会社 | Biosensor system, sensor chip and method for measuring analyte concentration in blood sample |
KR102007585B1 (en) | 2014-11-03 | 2019-08-05 | 에프. 호프만-라 로슈 아게 | Electrode arrangements for electrochemical test elements and methods of use thereof |
TWI531790B (en) | 2014-11-10 | 2016-05-01 | 五鼎生物技術股份有限公司 | Electrochemical test strip, measurement system and method for determining sample content in the reactive region of the electrochemical test strip |
US11680925B2 (en) * | 2014-11-25 | 2023-06-20 | Polymer Technology Systems, Inc. | Systems and methods for electrochemical hematocrit determination by alternate current impedance phase angle determinations |
EP4191239A1 (en) * | 2014-12-19 | 2023-06-07 | Roche Diagnostics GmbH | Test element for electrochemically detecting at least one analyte |
JP2019529935A (en) | 2016-10-05 | 2019-10-17 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | Detection reagents and electrode arrangements for multi-sample diagnostic test elements and methods of using them |
WO2018226775A1 (en) | 2017-06-08 | 2018-12-13 | Roche Diabetes Care, Inc. | Electrode break detection |
USD936855S1 (en) * | 2018-02-09 | 2021-11-23 | Euroimmun Medizinische Labordiagnostika Ag | Device or instrument for medical diagnostics |
US11703436B2 (en) * | 2020-01-30 | 2023-07-18 | MX3 Diagnostics, Inc. | Biological fluid sample assessment |
Family Cites Families (621)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US286735A (en) | 1883-10-16 | Heineicii eossleb | ||
US672094A (en) | 1900-08-27 | 1901-04-16 | George Cliffton | Feed-cooker. |
US2526651A (en) | 1945-08-02 | 1950-10-24 | Hydrocarbon Research Inc | Separating powdered catalysts from exothermically reactive gases |
GB787123A (en) | 1954-03-18 | 1957-12-04 | Rheinpreussen Ag | Apparatus for the catalytic gas reactions in liquid media |
US2883169A (en) | 1955-04-29 | 1959-04-21 | Mining Process & Patent Co | Aerating apparatus for flotation pulps |
US3526480A (en) | 1966-12-15 | 1970-09-01 | Xerox Corp | Automated chemical analyzer |
US3551295A (en) | 1967-11-29 | 1970-12-29 | Northrop Corp | Microbiological detection and identification system |
US3621381A (en) | 1968-10-16 | 1971-11-16 | Leeds & Northrup Co | Coulometric system having compensation for temperature induced viscosity changes |
BE754658A (en) | 1969-08-12 | 1971-02-10 | Merck Patent Gmbh | INDICATOR SHEET, CONSISTING OF AN IMPREGNATED, ABSORBENT, SHEATHED HAIR MATERIAL |
US3644824A (en) | 1970-02-09 | 1972-02-22 | Atomic Energy Authority Uk | Polarograph apparatus |
US3770607A (en) | 1970-04-07 | 1973-11-06 | Secretary | Glucose determination apparatus |
US3661748A (en) | 1970-04-07 | 1972-05-09 | Instrumentation Labor Inc | Fault sensing instrumentation |
US3656543A (en) | 1970-05-25 | 1972-04-18 | Foster Wheeler Corp | Liquid metal heat exchanger |
US3919627A (en) | 1970-08-06 | 1975-11-11 | Gerald F Allen | Conductivity measuring method and apparatus utilizing coaxial electrode cells |
US3776832A (en) | 1970-11-10 | 1973-12-04 | Energetics Science | Electrochemical detection cell |
US3720093A (en) | 1970-12-03 | 1973-03-13 | Us Navy | Carbon dioxide indicating meter |
US3718568A (en) * | 1971-05-21 | 1973-02-27 | Instrumentation Labor Inc | Electrochemical sensor instrumentation |
CH559912A5 (en) | 1971-09-09 | 1975-03-14 | Hoffmann La Roche | |
US3763422A (en) | 1971-10-21 | 1973-10-02 | Corning Glass Works | Method and apparatus for electrochemical analysis of small samples of blood |
US3870099A (en) * | 1972-05-19 | 1975-03-11 | Atomic Energy Commission | Seal assembly |
US3925183A (en) | 1972-06-16 | 1975-12-09 | Energetics Science | Gas detecting and quantitative measuring device |
US3902970A (en) | 1973-07-30 | 1975-09-02 | Leeds & Northrup Co | Flow-through amperometric measuring system and method |
CH585907A5 (en) | 1973-08-06 | 1977-03-15 | Hoffmann La Roche | |
US3993947A (en) * | 1974-09-19 | 1976-11-23 | Drexelbrook Controls, Inc. | Admittance measuring system for monitoring the condition of materials |
US3937615A (en) | 1974-12-17 | 1976-02-10 | Leeds & Northrup Company | Auto-ranging glucose measuring system |
FR2295419A1 (en) | 1974-12-21 | 1976-07-16 | Kyoto Daiichi Kagaku Kk | REFLECTANCE MEASURING DEVICE AND COMPOSITE TEST PAPER STRUCTURE SUBJECT TO SUCH MEASUREMENT |
US4052596A (en) | 1974-12-23 | 1977-10-04 | Hycel, Inc. | Automatic hematology analyzer |
US4060127A (en) | 1975-04-15 | 1977-11-29 | Nikolai Ivanovich Savin | Shell-and-tube heat exchanger |
US4008448A (en) | 1975-10-03 | 1977-02-15 | Polaroid Corporation | Solenoid with selectively arrestible plunger movement |
US4230537A (en) | 1975-12-18 | 1980-10-28 | Monsanto Company | Discrete biochemical electrode system |
US4040908A (en) | 1976-03-12 | 1977-08-09 | Children's Hospital Medical Center | Polarographic analysis of cholesterol and other macromolecular substances |
US4065263A (en) | 1976-04-02 | 1977-12-27 | Woodbridge Iii Richard G | Analytical test strip apparatus |
US4053381A (en) | 1976-05-19 | 1977-10-11 | Eastman Kodak Company | Device for determining ionic activity of components of liquid drops |
US4123701A (en) | 1976-07-01 | 1978-10-31 | United States Surgical Corporation | Disposable sample card having a well with electrodes for testing a liquid sample |
US4092635A (en) | 1976-09-20 | 1978-05-30 | Baxter Travenol Laboratories, Inc. | Humidity sensor alarm unit |
US4127448A (en) | 1977-02-28 | 1978-11-28 | Schick Karl G | Amperometric-non-enzymatic method of determining sugars and other polyhydroxy compounds |
US4214203A (en) | 1977-06-17 | 1980-07-22 | Unisearch Limited | Location and effect of adsorbed chemicals on the dielectric substructure of membranes by ultra low frequency spectrometry |
JPS5912135B2 (en) | 1977-09-28 | 1984-03-21 | 松下電器産業株式会社 | enzyme electrode |
JPS5460996A (en) | 1977-10-22 | 1979-05-16 | Mitsubishi Chem Ind | Method of measuring amount of sugar |
US4214968A (en) | 1978-04-05 | 1980-07-29 | Eastman Kodak Company | Ion-selective electrode |
DE2817363C2 (en) | 1978-04-20 | 1984-01-26 | Siemens AG, 1000 Berlin und 8000 München | Method for determining the concentration of sugar and a suitable electrocatalytic sugar sensor |
DE2823485C2 (en) | 1978-05-30 | 1986-03-27 | Albert Prof. Dr. 3550 Marburg Huch | Trough electrode |
US4184936A (en) | 1978-07-24 | 1980-01-22 | Eastman Kodak Company | Device for determining ionic activity |
US4233029A (en) | 1978-10-25 | 1980-11-11 | Eastman Kodak Company | Liquid transport device and method |
CA1129498A (en) | 1978-10-25 | 1982-08-10 | Richard L. Columbus | Structural configuration and method for transport of a liquid drop through an ingress aperture |
US4225410A (en) | 1978-12-04 | 1980-09-30 | Technicon Instruments Corporation | Integrated array of electrochemical sensors |
US4329642A (en) | 1979-03-09 | 1982-05-11 | Siliconix, Incorporated | Carrier and test socket for leadless integrated circuit |
US4273134A (en) | 1979-05-22 | 1981-06-16 | Biochem International Inc. | Fixation ring assembly and method of assembling a sensor head |
US4273639A (en) | 1979-06-20 | 1981-06-16 | Eastman Kodak Company | Capillary bridge in apparatus for determining ionic activity |
US4297569A (en) | 1979-06-28 | 1981-10-27 | Datakey, Inc. | Microelectronic memory key with receptacle and systems therefor |
US4265250A (en) | 1979-07-23 | 1981-05-05 | Battle Research And Development Associates | Electrode |
US4263343A (en) | 1979-08-13 | 1981-04-21 | Eastman Kodak Company | Reference elements for ion-selective membrane electrodes |
US4303887A (en) | 1979-10-29 | 1981-12-01 | United States Surgical Corporation | Electrical liquid conductivity measuring system |
US4301412A (en) | 1979-10-29 | 1981-11-17 | United States Surgical Corporation | Liquid conductivity measuring system and sample cards therefor |
US4628193A (en) | 1980-01-30 | 1986-12-09 | Blum Alvin S | Code reading operations supervisor |
US4323536A (en) | 1980-02-06 | 1982-04-06 | Eastman Kodak Company | Multi-analyte test device |
US4413407A (en) | 1980-03-10 | 1983-11-08 | Eastman Kodak Company | Method for forming an electrode-containing device with capillary transport between electrodes |
DE3029579C2 (en) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Method and means for separating plasma or serum from whole blood |
US4816224A (en) | 1980-08-05 | 1989-03-28 | Boehringer Mannheim Gmbh | Device for separating plasma or serum from whole blood and analyzing the same |
US4407959A (en) | 1980-10-29 | 1983-10-04 | Fuji Electric Co., Ltd. | Blood sugar analyzing apparatus |
US4413628A (en) | 1980-11-19 | 1983-11-08 | Tamulis Walter G | pH Monitor electrode electrolyte cartridge |
US4420564A (en) | 1980-11-21 | 1983-12-13 | Fuji Electric Company, Ltd. | Blood sugar analyzer having fixed enzyme membrane sensor |
DE3047782A1 (en) | 1980-12-18 | 1982-07-08 | Drägerwerk AG, 2400 Lübeck | CIRCUIT FOR THE CORRECTION OF THE SENSOR OUTPUT SIZE |
US4426451A (en) | 1981-01-28 | 1984-01-17 | Eastman Kodak Company | Multi-zoned reaction vessel having pressure-actuatable control means between zones |
US4436094A (en) | 1981-03-09 | 1984-03-13 | Evreka, Inc. | Monitor for continuous in vivo measurement of glucose concentration |
US4407290A (en) | 1981-04-01 | 1983-10-04 | Biox Technology, Inc. | Blood constituent measuring device and method |
AT369254B (en) | 1981-05-07 | 1982-12-27 | Otto Dipl Ing Dr Tech Prohaska | MEDICAL PROBE |
US4440175A (en) | 1981-08-10 | 1984-04-03 | University Patents, Inc. | Membrane electrode for non-ionic species |
DE3133826A1 (en) | 1981-08-27 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | ANALYSIS TEST STRIP AND METHOD FOR THE PRODUCTION THEREOF |
DE3137174A1 (en) | 1981-09-18 | 1983-04-07 | Boehringer Mannheim Gmbh, 6800 Mannheim | DEVICE FOR THE OPTICAL DETECTION OF A CODING ON A DIAGNOSTIC TEST STRIP |
DE3278334D1 (en) | 1981-10-23 | 1988-05-19 | Genetics Int Inc | Sensor for components of a liquid mixture |
US4431004A (en) | 1981-10-27 | 1984-02-14 | Bessman Samuel P | Implantable glucose sensor |
NZ199380A (en) | 1981-12-23 | 1986-08-08 | J R Baker | Determination of serum glucose levels in blood samples |
DE3202067C2 (en) | 1982-01-23 | 1984-06-20 | Holger Dr. 5100 Aachen Kiesewetter | Device for determining the hematocrit value |
DE3228542A1 (en) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | METHOD FOR DETERMINING THE CONCENTRATION OF ELECTROCHEMICALLY IMPLEMENTABLE SUBSTANCES |
DE3228551A1 (en) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | METHOD FOR DETERMINING SUGAR CONCENTRATION |
US4571292A (en) | 1982-08-12 | 1986-02-18 | Case Western Reserve University | Apparatus for electrochemical measurements |
US4467386A (en) | 1982-11-17 | 1984-08-21 | Rca Corporation | Fail-safe sensor circuit |
DE3245318C3 (en) | 1982-12-08 | 1996-06-20 | Bayer Ag | Process for carrying out pressure reactions with suspended catalysts |
US4679562A (en) | 1983-02-16 | 1987-07-14 | Cardiac Pacemakers, Inc. | Glucose sensor |
US5682884A (en) | 1983-05-05 | 1997-11-04 | Medisense, Inc. | Strip electrode with screen printing |
CA1219040A (en) | 1983-05-05 | 1987-03-10 | Elliot V. Plotkin | Measurement of enzyme-catalysed reactions |
CA1226036A (en) | 1983-05-05 | 1987-08-25 | Irving J. Higgins | Analytical equipment and sensor electrodes therefor |
US5509410A (en) | 1983-06-06 | 1996-04-23 | Medisense, Inc. | Strip electrode including screen printing of a single layer |
DE3326689A1 (en) | 1983-07-23 | 1985-01-31 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD AND DEVICE FOR PRODUCING A TEST STRIP |
US4517291A (en) | 1983-08-15 | 1985-05-14 | E. I. Du Pont De Nemours And Company | Biological detection process using polymer-coated electrodes |
US4552458A (en) | 1983-10-11 | 1985-11-12 | Eastman Kodak Company | Compact reflectometer |
SE8305704D0 (en) | 1983-10-18 | 1983-10-18 | Leo Ab | Cuvette |
US4703017C1 (en) | 1984-02-14 | 2001-12-04 | Becton Dickinson Co | Solid phase assay with visual readout |
DE3407754A1 (en) | 1984-03-02 | 1985-09-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | DEVICE FOR DETERMINING THE DIFFUSION REFLECTIVITY OF A SAMPLE AREA OF SMALL DIMENSIONS |
GB8406752D0 (en) | 1984-03-15 | 1984-04-18 | Unilever Plc | Chemical and clinical tests |
US4849330A (en) | 1984-04-27 | 1989-07-18 | Molecular Devices Corporation | Photoresponsive redox detection and discrimination |
CA1261256A (en) | 1984-06-13 | 1989-09-26 | Ian A. Shanks | Devices for use in chemical test procedures |
US5141868A (en) | 1984-06-13 | 1992-08-25 | Internationale Octrooi Maatschappij "Octropa" Bv | Device for use in chemical test procedures |
JPS6134031A (en) | 1984-07-26 | 1986-02-18 | Nippon Paint Co Ltd | Surface treatment apparatus |
US4820399A (en) | 1984-08-31 | 1989-04-11 | Shimadzu Corporation | Enzyme electrodes |
US4648665A (en) | 1984-10-16 | 1987-03-10 | Amp Incorporated | Electronic key assemblies |
WO1986002732A1 (en) | 1984-10-31 | 1986-05-09 | Unilever Plc | Apparatus for use in electrical, e.g. electrochemical, measurement procedures, and its production and use, and composite assemblies incorporating the apparatus |
US4713347A (en) | 1985-01-14 | 1987-12-15 | Sensor Diagnostics, Inc. | Measurement of ligand/anti-ligand interactions using bulk conductance |
GB8504521D0 (en) | 1985-02-21 | 1985-03-27 | Genetics Int Inc | Electrochemical assay |
US5279294A (en) * | 1985-04-08 | 1994-01-18 | Cascade Medical, Inc. | Medical diagnostic system |
US4652830A (en) | 1985-04-18 | 1987-03-24 | Eg&G Ocean Products, Inc. | Analyzer for comparative measurements of bulk conductivity |
US4671288A (en) | 1985-06-13 | 1987-06-09 | The Regents Of The University Of California | Electrochemical cell sensor for continuous short-term use in tissues and blood |
EP0230472B2 (en) | 1985-06-21 | 2000-12-13 | Matsushita Electric Industrial Co., Ltd. | Biosensor and method of manufacturing same |
US4938860A (en) | 1985-06-28 | 1990-07-03 | Miles Inc. | Electrode for electrochemical sensors |
DE3525986A1 (en) * | 1985-07-20 | 1987-01-29 | Hochtemperatur Kernkraftwerk | LIQUID SUPPLY AS A RBER PRESSURE VALVE |
US4686479A (en) | 1985-07-22 | 1987-08-11 | Young Chung C | Apparatus and control kit for analyzing blood sample values including hematocrit |
US4806312A (en) | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having detectable signal concentrating zone |
US4806311A (en) | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having labeled reagent concentration zone |
US4734184A (en) | 1985-08-29 | 1988-03-29 | Diamond Sensor Systems, Inc. | Self-activating hydratable solid-state electrode apparatus |
US4805624A (en) | 1985-09-09 | 1989-02-21 | The Montefiore Hospital Association Of Western Pa | Low-potential electrochemical redox sensors |
EP0215669A3 (en) | 1985-09-17 | 1989-08-30 | Seiko Instruments Inc. | Analytical device and method for analysis of biochemicals, microbes and cells |
US5500350A (en) * | 1985-10-30 | 1996-03-19 | Celltech Limited | Binding assay device |
US4714874A (en) | 1985-11-12 | 1987-12-22 | Miles Inc. | Test strip identification and instrument calibration |
US4935106A (en) | 1985-11-15 | 1990-06-19 | Smithkline Diagnostics, Inc. | Ion selective/enzymatic electrode medical analyzer device and method of use |
GB8608700D0 (en) | 1986-04-10 | 1986-05-14 | Genetics Int Inc | Measurement of electroactive species in solution |
US4795542A (en) | 1986-04-24 | 1989-01-03 | St. Jude Medical, Inc. | Electrochemical concentration detector device |
FR2598227B1 (en) | 1986-04-30 | 1989-07-28 | Bio Merieux | METHOD FOR DETECTION AND / OR IDENTIFICATION OF A BIOLOGICAL SUBSTANCE IN A LIQUID MEDIUM USING ELECTRICAL MEASUREMENTS, AND DEVICE FOR CARRYING OUT SAID METHOD |
US5066372A (en) | 1986-05-02 | 1991-11-19 | Ciba Corning Diagnostics Corp. | Unitary multiple electrode sensor |
US4703756A (en) | 1986-05-06 | 1987-11-03 | The Regents Of The University Of California | Complete glucose monitoring system with an implantable, telemetered sensor module |
US5324335A (en) | 1986-05-08 | 1994-06-28 | Rentech, Inc. | Process for the production of hydrocarbons |
US4731726A (en) | 1986-05-19 | 1988-03-15 | Healthware Corporation | Patient-operated glucose monitor and diabetes management system |
GB8612861D0 (en) | 1986-05-27 | 1986-07-02 | Cambridge Life Sciences | Immobilised enzyme biosensors |
US4750496A (en) | 1987-01-28 | 1988-06-14 | Xienta, Inc. | Method and apparatus for measuring blood glucose concentration |
JPS636451A (en) | 1986-06-27 | 1988-01-12 | Terumo Corp | Enzyme sensor |
GB8618022D0 (en) | 1986-07-23 | 1986-08-28 | Unilever Plc | Electrochemical measurements |
US5049487A (en) | 1986-08-13 | 1991-09-17 | Lifescan, Inc. | Automated initiation of timing of reflectance readings |
US5059394A (en) | 1986-08-13 | 1991-10-22 | Lifescan, Inc. | Analytical device for the automated determination of analytes in fluids |
US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US4865873A (en) | 1986-09-15 | 1989-09-12 | General Electric Company | Electroless deposition employing laser-patterned masking layer |
US4897162A (en) | 1986-11-14 | 1990-01-30 | The Cleveland Clinic Foundation | Pulse voltammetry |
DE3643263A1 (en) | 1986-12-18 | 1988-07-07 | Horst Dipl Ing Hommel | Method and device for identifying metabolic disturbances by examination of the urine, in particular for early identification of a tendency to lithogenesis in the urine donor |
JPH039267Y2 (en) | 1986-12-27 | 1991-03-07 | ||
GB2201248B (en) | 1987-02-24 | 1991-04-17 | Ici Plc | Enzyme electrode sensors |
US4759828A (en) | 1987-04-09 | 1988-07-26 | Nova Biomedical Corporation | Glucose electrode and method of determining glucose |
CA1315181C (en) | 1987-04-13 | 1993-03-30 | Joel M. Blatt | Test strip device with volume metering capillary gap |
US4956275A (en) | 1987-04-14 | 1990-09-11 | Molecular Devices Corporation | Migratory detection immunoassay |
EP0290683A3 (en) | 1987-05-01 | 1988-12-14 | Diva Medical Systems B.V. | Diabetes management system and apparatus |
DE3715938A1 (en) | 1987-05-13 | 1988-11-24 | Boehringer Mannheim Gmbh | CONTAINER FOR TEST STRIP |
US4975647A (en) | 1987-06-01 | 1990-12-04 | Nova Biomedical Corporation | Controlling machine operation with respect to consumable accessory units |
US4797256A (en) | 1987-06-05 | 1989-01-10 | Boehringer Mannheim Corporation | Registration device for blood test strips |
US5447837A (en) | 1987-08-05 | 1995-09-05 | Calypte, Inc. | Multi-immunoassay diagnostic system for antigens or antibodies or both |
US4812210A (en) | 1987-10-16 | 1989-03-14 | The United States Department Of Energy | Measuring surfactant concentration in plating solutions |
US4929426A (en) | 1987-11-02 | 1990-05-29 | Biologix, Inc. | Portable blood chemistry measuring apparatus |
US4940945A (en) | 1987-11-02 | 1990-07-10 | Biologix Inc. | Interface circuit for use in a portable blood chemistry measuring apparatus |
DE3742786A1 (en) | 1987-12-17 | 1989-06-29 | Boehringer Mannheim Gmbh | ANALYSIS SYSTEM FOR DETERMINING A COMPONENT OF A LIQUID |
US4832814A (en) | 1987-12-28 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Electrofusion cell and method of making the same |
US4877580A (en) | 1988-02-09 | 1989-10-31 | Technimed Corporation | Assay kit including an analyte test strip and a color comparator |
JP2641236B2 (en) | 1988-03-09 | 1997-08-13 | 雪印乳業株式会社 | Sterilization method of immobilized biocatalyst and reactor with fluidized tank |
US5108564A (en) | 1988-03-15 | 1992-04-28 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
US5128015A (en) | 1988-03-15 | 1992-07-07 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
EP0359831B2 (en) | 1988-03-31 | 2007-06-20 | Matsushita Electric Industrial Co., Ltd. | Biosensor and process for its production |
US4954087A (en) | 1988-04-27 | 1990-09-04 | I-Stat Corporation | Static-free interrogating connector for electric components |
US5112758A (en) | 1988-05-09 | 1992-05-12 | Epitope, Inc. | Treating body fluids for diagnostic testing |
ES2085854T3 (en) | 1988-08-02 | 1996-06-16 | Abbott Lab | METHOD AND DEVICE FOR THE PRODUCTION OF CALIBRATION DATA FOR ANALYSIS. |
US5075077A (en) | 1988-08-02 | 1991-12-24 | Abbott Laboratories | Test card for performing assays |
US5096669A (en) * | 1988-09-15 | 1992-03-17 | I-Stat Corporation | Disposable sensing device for real time fluid analysis |
US5439826A (en) | 1988-12-02 | 1995-08-08 | Bio-Tek Instruments, Inc. | Method of distinguishing among strips for different assays in an automated instrument |
US5039618A (en) | 1989-02-02 | 1991-08-13 | Hybrivet Systems, Inc. | Test swab cartridge type device and method for detecting lead and cadmium |
US5118183A (en) | 1989-02-10 | 1992-06-02 | X-Rite, Incorporated | Automated strip reader densitometer |
JP2654682B2 (en) | 1989-02-17 | 1997-09-17 | 富士写真フイルム株式会社 | Biochemical analyzer, biochemical analysis correction method and correction value recording medium |
US5053199A (en) | 1989-02-21 | 1991-10-01 | Boehringer Mannheim Corporation | Electronically readable information carrier |
US5269891A (en) | 1989-03-09 | 1993-12-14 | Novo Nordisk A/S | Method and apparatus for determination of a constituent in a fluid |
US5312762A (en) | 1989-03-13 | 1994-05-17 | Guiseppi Elie Anthony | Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte |
DE3910262C1 (en) | 1989-03-30 | 1990-11-08 | Deutsche Gesellschaft Fuer Wiederaufarbeitung Von Kernbrennstoffen Mbh, 3000 Hannover, De | |
DE3911539A1 (en) | 1989-04-08 | 1990-10-11 | Boehringer Mannheim Gmbh | TEST CARRIER ANALYSIS SYSTEM |
US4960546B1 (en) | 1989-04-19 | 1996-04-09 | Environmental Dynamics Inc | Diffuser mounting arrangement for waste water aeration systems |
US5234813A (en) | 1989-05-17 | 1993-08-10 | Actimed Laboratories, Inc. | Method and device for metering of fluid samples and detection of analytes therein |
DD301250A7 (en) | 1989-05-24 | 1992-11-05 | Akad Wissenschaften Ddr | Measuring apparatus and method for automatically determining the concentration of biocatalyst substrates |
CH677149A5 (en) | 1989-07-07 | 1991-04-15 | Disetronic Ag | |
US4976724A (en) | 1989-08-25 | 1990-12-11 | Lifescan, Inc. | Lancet ejector mechanism |
US5620863A (en) | 1989-08-28 | 1997-04-15 | Lifescan, Inc. | Blood glucose strip having reduced side reactions |
US6395227B1 (en) | 1989-08-28 | 2002-05-28 | Lifescan, Inc. | Test strip for measuring analyte concentration over a broad range of sample volume |
AU640162B2 (en) | 1989-08-28 | 1993-08-19 | Lifescan, Inc. | Blood separation and analyte detection techniques |
US5306623A (en) | 1989-08-28 | 1994-04-26 | Lifescan, Inc. | Visual blood glucose concentration test strip |
US5018164A (en) | 1989-09-12 | 1991-05-21 | Hughes Aircraft Company | Excimer laser ablation method and apparatus for microcircuit fabrication |
JP2665806B2 (en) | 1989-09-13 | 1997-10-22 | 株式会社豊田中央研究所 | Hematocrit measuring device |
US5639671A (en) | 1989-09-18 | 1997-06-17 | Biostar, Inc. | Methods for optimizing of an optical assay device |
DE3940152A1 (en) | 1989-12-05 | 1991-06-06 | Boehringer Mannheim Gmbh | TEST STRIP EVALUATOR FOR MULTIPLE TEST STRIPS |
US4999582A (en) * | 1989-12-15 | 1991-03-12 | Boehringer Mannheim Corp. | Biosensor electrode excitation circuit |
US4963814A (en) | 1989-12-15 | 1990-10-16 | Boehringer Mannheim Corporation | Regulated bifurcated power supply |
US4999632A (en) * | 1989-12-15 | 1991-03-12 | Boehringer Mannheim Corporation | Analog to digital conversion with noise reduction |
US5508171A (en) | 1989-12-15 | 1996-04-16 | Boehringer Mannheim Corporation | Assay method with enzyme electrode system |
EP0505494B1 (en) * | 1989-12-15 | 1995-07-12 | Boehringer Mannheim Corporation | Redox mediator reagent and biosensor |
US5243516A (en) | 1989-12-15 | 1993-09-07 | Boehringer Mannheim Corporation | Biosensing instrument and method |
DE4003194A1 (en) | 1990-02-03 | 1991-08-08 | Boehringer Mannheim Gmbh | Electrochemical determn. of analytes - using oxido-reductase and substance of being reduced, which is re-oxidised on the electrode |
US5286362A (en) * | 1990-02-03 | 1994-02-15 | Boehringer Mannheim Gmbh | Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor |
US5141850A (en) | 1990-02-07 | 1992-08-25 | Hygeia Sciences, Inc. | Porous strip form assay device method |
US5187100A (en) * | 1990-05-29 | 1993-02-16 | Lifescan, Inc. | Dispersion to limit penetration of aqueous solutions into a membrane |
US5250439A (en) | 1990-07-19 | 1993-10-05 | Miles Inc. | Use of conductive sensors in diagnostic assays |
US5112455A (en) | 1990-07-20 | 1992-05-12 | I Stat Corporation | Method for analytically utilizing microfabricated sensors during wet-up |
JPH0820412B2 (en) | 1990-07-20 | 1996-03-04 | 松下電器産業株式会社 | Quantitative analysis method and device using disposable sensor |
US5124661A (en) | 1990-07-23 | 1992-06-23 | I-Stat Corporation | Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments |
US5182707A (en) * | 1990-07-23 | 1993-01-26 | Healthdyne, Inc. | Apparatus for recording reagent test strip data by comparison to color lights on a reference panel |
US5569591A (en) | 1990-08-03 | 1996-10-29 | University College Of Wales Aberystwyth | Analytical or monitoring apparatus and method |
US5120421A (en) | 1990-08-31 | 1992-06-09 | The United States Of America As Represented By The United States Department Of Energy | Electrochemical sensor/detector system and method |
US5526808A (en) | 1990-10-04 | 1996-06-18 | Microcor, Inc. | Method and apparatus for noninvasively determining hematocrit |
US5642734A (en) | 1990-10-04 | 1997-07-01 | Microcor, Inc. | Method and apparatus for noninvasively determining hematocrit |
DE4041905A1 (en) * | 1990-12-27 | 1992-07-02 | Boehringer Mannheim Gmbh | TEST CARRIER ANALYSIS SYSTEM |
US5126952A (en) | 1991-01-22 | 1992-06-30 | Eastman Kodak Company | Bar coding calibration |
JP3118552B2 (en) * | 1991-02-27 | 2000-12-18 | ロッシュ ダイアグノスティックス コーポレイション | Apparatus and method for analyzing body fluid |
US5232668A (en) | 1991-02-27 | 1993-08-03 | Boehringer Mannheim Corporation | Test strip holding and reading mechanism for a meter |
JP3251583B2 (en) * | 1991-02-27 | 2002-01-28 | ロシュ ダイアグノスティックス コーポレーション | How to communicate with microcomputer controlled instruments |
US5246858A (en) | 1991-02-27 | 1993-09-21 | Boehringer Mannheim Corporation | Apparatus and method for analyzing a body fluid |
US5192415A (en) * | 1991-03-04 | 1993-03-09 | Matsushita Electric Industrial Co., Ltd. | Biosensor utilizing enzyme and a method for producing the same |
US5593852A (en) | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
DE4117847A1 (en) | 1991-05-31 | 1992-12-03 | Lre Relais & Elektronik Gmbh | Evaluating bar coded optical information - subjecting output from sensor to peak and min. valve generation with comparison process |
US5232516A (en) | 1991-06-04 | 1993-08-03 | Implemed, Inc. | Thermoelectric device with recuperative heat exchangers |
GB9113211D0 (en) * | 1991-06-19 | 1991-08-07 | Hypoguard Uk Ltd | Support membrane |
DE4123348A1 (en) * | 1991-07-15 | 1993-01-21 | Boehringer Mannheim Gmbh | ELECTROCHEMICAL ANALYSIS SYSTEM |
US5179288A (en) * | 1991-09-30 | 1993-01-12 | Ortho Pharmaceutical Corporation | Apparatus and method for measuring a bodily constituent |
JP2960265B2 (en) * | 1991-10-18 | 1999-10-06 | 松下電器産業株式会社 | Biosensor and measurement method using the same |
US5264103A (en) | 1991-10-18 | 1993-11-23 | Matsushita Electric Industrial Co., Ltd. | Biosensor and a method for measuring a concentration of a substrate in a sample |
US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
US5220920A (en) | 1991-11-08 | 1993-06-22 | Via Medical Corporation | Electrochemical measurement system having interference reduction circuit |
IL103674A0 (en) | 1991-11-19 | 1993-04-04 | Houston Advanced Res Center | Method and apparatus for molecule detection |
JP3135959B2 (en) | 1991-12-12 | 2001-02-19 | アークレイ株式会社 | Biosensor and separation and quantification method using the same |
US5217594A (en) | 1992-01-15 | 1993-06-08 | Enzyme Technology Research Group, Inc. | Convenient determination of trace lead in whole blood and other fluids |
EP0555045B1 (en) | 1992-02-03 | 1997-10-08 | Lifescan, Inc. | Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes |
US5635364A (en) | 1992-03-27 | 1997-06-03 | Abbott Laboratories | Assay verification control for an automated analytical system |
US5296192A (en) * | 1992-04-03 | 1994-03-22 | Home Diagnostics, Inc. | Diagnostic test strip |
US5353351A (en) | 1992-06-09 | 1994-10-04 | At&T Bell Laboratories | Secure teleconferencing |
GB9215733D0 (en) | 1992-07-24 | 1992-09-09 | British Tech Group | Method of and apparatus for determining a property of a sample |
CA2105940C (en) | 1992-10-05 | 2001-12-25 | Robert M. Koros | Bubble column, tube side slurry process and apparatus |
US5387327A (en) | 1992-10-19 | 1995-02-07 | Duquesne University Of The Holy Ghost | Implantable non-enzymatic electrochemical glucose sensor |
US5508200A (en) | 1992-10-19 | 1996-04-16 | Tiffany; Thomas | Method and apparatus for conducting multiple chemical assays |
US5342790A (en) | 1992-10-30 | 1994-08-30 | Becton Dickinson And Company | Apparatus for indirect fluorescent assay of blood samples |
US5389215A (en) * | 1992-11-05 | 1995-02-14 | Nippon Telegraph And Telephone Corporation | Electrochemical detection method and apparatus therefor |
JP2954436B2 (en) | 1992-11-11 | 1999-09-27 | 株式会社日立製作所 | Test piece supply device and analyzer using the same |
US6168563B1 (en) * | 1992-11-17 | 2001-01-02 | Health Hero Network, Inc. | Remote health monitoring and maintenance system |
US5371687A (en) * | 1992-11-20 | 1994-12-06 | Boehringer Mannheim Corporation | Glucose test data acquisition and management system |
ZA938555B (en) | 1992-11-23 | 1994-08-02 | Lilly Co Eli | Technique to improve the performance of electrochemical sensors |
US5344754A (en) | 1993-01-13 | 1994-09-06 | Avocet Medical, Inc. | Assay timed by electrical resistance change and test strip |
NZ250750A (en) | 1993-01-27 | 1995-02-24 | Sasol Chem Ind Pty | Reacting gases in a slurry bed which contains a filtration zone to separate liquid product |
US5515847A (en) | 1993-01-28 | 1996-05-14 | Optiscan, Inc. | Self-emission noninvasive infrared spectrophotometer |
FR2701117B1 (en) * | 1993-02-04 | 1995-03-10 | Asulab Sa | Electrochemical measurement system with multizone sensor, and its application to glucose measurement. |
IL109159A (en) | 1993-03-29 | 2003-11-23 | Isk Biotech Corp | Immunoassays for tetrachloroiso-phthalonitrile and its metabolites and antibodies for use therein |
DE4310583A1 (en) | 1993-03-31 | 1994-10-06 | Boehringer Mannheim Gmbh | Test strip analysis system |
DE4313253A1 (en) | 1993-04-23 | 1994-10-27 | Boehringer Mannheim Gmbh | System for analyzing the contents of liquid samples |
DK0622119T3 (en) * | 1993-04-23 | 2000-04-10 | Roche Diagnostics Gmbh | Test element storage system |
US5376254A (en) | 1993-05-14 | 1994-12-27 | Fisher; Arkady V. | Potentiometric electrochemical device for qualitative and quantitative analysis |
US5843691A (en) | 1993-05-15 | 1998-12-01 | Lifescan, Inc. | Visually-readable reagent test strip |
JP3713516B2 (en) | 1993-05-29 | 2005-11-09 | ケンブリッジ ライフ サイエンシズ パブリック リミテッド カンパニー | Sensors based on polymer transformations |
DE4318519C2 (en) | 1993-06-03 | 1996-11-28 | Fraunhofer Ges Forschung | Electrochemical sensor |
US5385846A (en) * | 1993-06-03 | 1995-01-31 | Boehringer Mannheim Corporation | Biosensor and method for hematocrit determination |
CA2153883C (en) | 1993-06-08 | 1999-02-09 | Bradley E. White | Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips |
US5405511A (en) | 1993-06-08 | 1995-04-11 | Boehringer Mannheim Corporation | Biosensing meter with ambient temperature estimation method and system |
US5352351A (en) * | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
US5366609A (en) | 1993-06-08 | 1994-11-22 | Boehringer Mannheim Corporation | Biosensing meter with pluggable memory key |
US5527473A (en) | 1993-07-15 | 1996-06-18 | Ackerman; Carl D. | Process for performing reactions in a liquid-solid catalyst slurry |
DE4323672A1 (en) | 1993-07-15 | 1995-01-19 | Boehringer Mannheim Gmbh | Device for the simultaneous determination of analytes |
US5413690A (en) | 1993-07-23 | 1995-05-09 | Boehringer Mannheim Corporation | Potentiometric biosensor and the method of its use |
US5658443A (en) | 1993-07-23 | 1997-08-19 | Matsushita Electric Industrial Co., Ltd. | Biosensor and method for producing the same |
US5748002A (en) | 1996-01-26 | 1998-05-05 | Phase Dynamics Inc. | RF probe for montoring composition of substances |
US5508203A (en) | 1993-08-06 | 1996-04-16 | Fuller; Milton E. | Apparatus and method for radio frequency spectroscopy using spectral analysis |
US5792668A (en) | 1993-08-06 | 1998-08-11 | Solid State Farms, Inc. | Radio frequency spectral analysis for in-vitro or in-vivo environments |
CA2170402C (en) | 1993-08-24 | 2000-07-18 | Michael P. Allen | Novel disposable electronic assay device |
US5837546A (en) | 1993-08-24 | 1998-11-17 | Metrika, Inc. | Electronic assay device and method |
US5494831A (en) | 1993-08-30 | 1996-02-27 | Hughes Aircraft Company | Electrochemical immunosensor system and methods |
US5526111A (en) | 1993-08-31 | 1996-06-11 | Boehringer Mannheim Corporation | Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control |
US5522255A (en) * | 1993-08-31 | 1996-06-04 | Boehringer Mannheim Corporation | Fluid dose, flow and coagulation sensor for medical instrument |
DE69430926T2 (en) | 1993-08-31 | 2003-02-06 | Roche Diagnostics Corp | ANALOG HEATING CONTROL FOR A MEDICAL INSTRUMENT |
US5437772A (en) | 1993-11-01 | 1995-08-01 | The Electrosynthesis Co., Inc. | Portable lead detector |
JPH07128338A (en) | 1993-11-02 | 1995-05-19 | Kyoto Daiichi Kagaku:Kk | Convenient blood sugar meter and data managing method therefor |
US5421189A (en) | 1994-01-21 | 1995-06-06 | Ciba Corning Diagnostics Corp. | Electrical connection system for electrochemical sensors |
US5762770A (en) | 1994-02-21 | 1998-06-09 | Boehringer Mannheim Corporation | Electrochemical biosensor test strip |
US5437999A (en) | 1994-02-22 | 1995-08-01 | Boehringer Mannheim Corporation | Electrochemical sensor |
US5536249A (en) * | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
US5583432A (en) | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
DE4417245A1 (en) | 1994-04-23 | 1995-10-26 | Lpkf Cad Cam Systeme Gmbh | High resolution structured metallisation prodn. |
JP3331253B2 (en) | 1994-05-10 | 2002-10-07 | バイエルコーポレーション | Test strip removal device for automatic analyzer |
JP3027306B2 (en) | 1994-06-02 | 2000-04-04 | 松下電器産業株式会社 | Biosensor and manufacturing method thereof |
US5700695A (en) | 1994-06-30 | 1997-12-23 | Zia Yassinzadeh | Sample collection and manipulation method |
US5477326A (en) | 1994-06-30 | 1995-12-19 | Bayer Corporation | Spectrophotometer arrangement with multi-detector readhead |
GB9415499D0 (en) | 1994-08-01 | 1994-09-21 | Bartlett Philip N | Electrodes and their use in analysis |
US5563031A (en) | 1994-09-08 | 1996-10-08 | Lifescan, Inc. | Highly stable oxidative coupling dye for spectrophotometric determination of analytes |
US6335203B1 (en) * | 1994-09-08 | 2002-01-01 | Lifescan, Inc. | Optically readable strip for analyte detection having on-strip orientation index |
US5515170A (en) | 1994-09-08 | 1996-05-07 | Lifescan, Inc. | Analyte detection device having a serpentine passageway for indicator strips |
WO1996007908A1 (en) | 1994-09-08 | 1996-03-14 | Lifescan, Inc. | Optically readable strip for analyte detection having on-strip standard |
US5526120A (en) | 1994-09-08 | 1996-06-11 | Lifescan, Inc. | Test strip with an asymmetrical end insuring correct insertion for measuring |
US5922530A (en) | 1994-09-08 | 1999-07-13 | Lifescan, Inc. | Stable coupling dye for photometric determination of analytes |
GB9419882D0 (en) | 1994-10-03 | 1994-11-16 | Mcnaughtan Arthur | Electrochemical detection system |
US5597532A (en) * | 1994-10-20 | 1997-01-28 | Connolly; James | Apparatus for determining substances contained in a body fluid |
US5504011A (en) | 1994-10-21 | 1996-04-02 | International Technidyne Corporation | Portable test apparatus and associated method of performing a blood coagulation test |
IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US5572159A (en) | 1994-11-14 | 1996-11-05 | Nexgen, Inc. | Voltage-controlled delay element with programmable delay |
KR0151203B1 (en) | 1994-12-08 | 1998-12-01 | 이헌조 | Multi-electrode type biosensor |
US5630986A (en) | 1995-01-13 | 1997-05-20 | Bayer Corporation | Dispensing instrument for fluid monitoring sensors |
US5569608A (en) | 1995-01-30 | 1996-10-29 | Bayer Corporation | Quantitative detection of analytes on immunochromatographic strips |
US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
EP0727925A1 (en) * | 1995-02-14 | 1996-08-21 | Lpkf Cad/Cam Systeme Gmbh | Process for structured metallizing of the surface of substrates |
US5567301A (en) | 1995-03-01 | 1996-10-22 | Illinois Institute Of Technology | Antibody covalently bound film immunobiosensor |
US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
US5650062A (en) | 1995-03-17 | 1997-07-22 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
US6170318B1 (en) * | 1995-03-27 | 2001-01-09 | California Institute Of Technology | Methods of use for sensor based fluid detection devices |
US5788833A (en) | 1995-03-27 | 1998-08-04 | California Institute Of Technology | Sensors for detecting analytes in fluids |
JP3498105B2 (en) * | 1995-04-07 | 2004-02-16 | アークレイ株式会社 | Sensor, method for manufacturing the same, and measuring method using the sensor |
US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
US5656502A (en) | 1995-06-07 | 1997-08-12 | Diagnostic Chemicals Limited | Test strip holder and method of use |
AUPN363995A0 (en) | 1995-06-19 | 1995-07-13 | Memtec Limited | Electrochemical cell |
US6413410B1 (en) | 1996-06-19 | 2002-07-02 | Lifescan, Inc. | Electrochemical cell |
US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US5611900A (en) | 1995-07-20 | 1997-03-18 | Michigan State University | Microbiosensor used in-situ |
US5698083A (en) | 1995-08-18 | 1997-12-16 | Regents Of The University Of California | Chemiresistor urea sensor |
AU6904496A (en) * | 1995-08-22 | 1997-03-19 | Andcare, Inc. | Handheld electromonitor device |
US5786584A (en) | 1995-09-06 | 1998-07-28 | Eli Lilly And Company | Vial and cartridge reading device providing audio feedback for a blood glucose monitoring system |
US5658802A (en) | 1995-09-07 | 1997-08-19 | Microfab Technologies, Inc. | Method and apparatus for making miniaturized diagnostic arrays |
US5650061A (en) | 1995-09-18 | 1997-07-22 | The Regents Of The University Of California | Large amplitude sinusoidal voltammetry |
US5665215A (en) | 1995-09-25 | 1997-09-09 | Bayer Corporation | Method and apparatus for making predetermined events with a biosensor |
US5628890A (en) | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
US6689265B2 (en) | 1995-10-11 | 2004-02-10 | Therasense, Inc. | Electrochemical analyte sensors using thermostable soybean peroxidase |
AU722471B2 (en) | 1995-10-17 | 2000-08-03 | Lifescan, Inc. | Blood glucose strip having reduced sensitivity to hematocrit |
US6777243B2 (en) | 1995-10-30 | 2004-08-17 | Arkray Inc. | Method for measuring substance and testing piece |
US6521110B1 (en) * | 1995-11-16 | 2003-02-18 | Lifescan, Inc. | Electrochemical cell |
US6174420B1 (en) * | 1996-11-15 | 2001-01-16 | Usf Filtration And Separations Group, Inc. | Electrochemical cell |
US6638415B1 (en) | 1995-11-16 | 2003-10-28 | Lifescan, Inc. | Antioxidant sensor |
US6863801B2 (en) | 1995-11-16 | 2005-03-08 | Lifescan, Inc. | Electrochemical cell |
AUPN661995A0 (en) * | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
JPH09207343A (en) | 1995-11-29 | 1997-08-12 | Matsushita Electric Ind Co Ltd | Laser machining method |
US5755953A (en) | 1995-12-18 | 1998-05-26 | Abbott Laboratories | Interference free biosensor |
JP3365184B2 (en) | 1996-01-10 | 2003-01-08 | 松下電器産業株式会社 | Biosensor |
CA2245664A1 (en) * | 1996-02-08 | 1997-08-14 | Australian Membrane And Biotechnology Research Institute | Enzyme detection biosensors |
US5989917A (en) | 1996-02-13 | 1999-11-23 | Selfcare, Inc. | Glucose monitor and test strip containers for use in same |
US5708247A (en) * | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
US6241862B1 (en) | 1996-02-14 | 2001-06-05 | Inverness Medical Technology, Inc. | Disposable test strips with integrated reagent/blood separation layer |
US5605837A (en) * | 1996-02-14 | 1997-02-25 | Lifescan, Inc. | Control solution for a blood glucose monitor |
DE19605583A1 (en) | 1996-02-15 | 1997-08-21 | Bayer Ag | Electrochemical sensors with improved selectivity and increased sensitivity |
US5801057A (en) | 1996-03-22 | 1998-09-01 | Smart; Wilson H. | Microsampling device and method of construction |
DE19612680C2 (en) | 1996-03-29 | 2000-02-03 | Inst Chemo Biosensorik | Cation selective sensor |
US5723284A (en) | 1996-04-01 | 1998-03-03 | Bayer Corporation | Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood |
US5962215A (en) | 1996-04-05 | 1999-10-05 | Mercury Diagnostics, Inc. | Methods for testing the concentration of an analyte in a body fluid |
US5890489A (en) | 1996-04-23 | 1999-04-06 | Dermal Therapy (Barbados) Inc. | Method for non-invasive determination of glucose in body fluids |
US6001307A (en) * | 1996-04-26 | 1999-12-14 | Kyoto Daiichi Kagaku Co., Ltd. | Device for analyzing a sample |
DE19621241C2 (en) * | 1996-05-25 | 2000-03-16 | Manfred Kessler | Membrane electrode for measuring the glucose concentration in liquids |
US5781024A (en) | 1996-07-26 | 1998-07-14 | Diametrics Medical, Inc. | Instrument performance verification system |
US5719667A (en) * | 1996-07-30 | 1998-02-17 | Bayer Corporation | Apparatus for filtering a laser beam in an analytical instrument |
US5883378A (en) | 1996-07-30 | 1999-03-16 | Bayer Corporation | Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles |
US5745308A (en) | 1996-07-30 | 1998-04-28 | Bayer Corporation | Methods and apparatus for an optical illuminator assembly and its alignment |
US5691486A (en) | 1996-07-30 | 1997-11-25 | Bayer Corporation | Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents |
US5753101A (en) | 1996-08-01 | 1998-05-19 | Ludwig; Frank A. | Method of monitoring constituents in conversion coating baths |
US5958791A (en) | 1996-09-27 | 1999-09-28 | Innovative Biotechnologies, Inc. | Interdigitated electrode arrays for liposome-enhanced immunoassay and test device |
US6358752B1 (en) | 1996-09-27 | 2002-03-19 | Cornell Research Foundation, Inc. | Liposome-enhanced test device and method |
US5925293A (en) | 1996-10-04 | 1999-07-20 | General Signal Corporation | Mixer sparging apparatus |
US5945341A (en) | 1996-10-21 | 1999-08-31 | Bayer Corporation | System for the optical identification of coding on a diagnostic test strip |
GB9622304D0 (en) | 1996-10-26 | 1996-12-18 | Univ Manchester | Sensor |
US5856195A (en) | 1996-10-30 | 1999-01-05 | Bayer Corporation | Method and apparatus for calibrating a sensor element |
US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
US6632349B1 (en) | 1996-11-15 | 2003-10-14 | Lifescan, Inc. | Hemoglobin sensor |
WO1998028623A1 (en) | 1996-12-20 | 1998-07-02 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
JP3460183B2 (en) | 1996-12-24 | 2003-10-27 | 松下電器産業株式会社 | Biosensor |
DE69809391T2 (en) | 1997-02-06 | 2003-07-10 | Therasense Inc | SMALL VOLUME SENSOR FOR IN-VITRO DETERMINATION |
EP0859230A1 (en) | 1997-02-10 | 1998-08-19 | Cranfield University | Detection of analytes using electrochemistry |
US6391558B1 (en) | 1997-03-18 | 2002-05-21 | Andcare, Inc. | Electrochemical detection of nucleic acid sequences |
AUPO581397A0 (en) | 1997-03-21 | 1997-04-17 | Memtec America Corporation | Sensor connection means |
US6226081B1 (en) | 1997-03-24 | 2001-05-01 | Optikos Corporation | Optical height of fill detection system and associated methods |
AUPO585797A0 (en) | 1997-03-25 | 1997-04-24 | Memtec America Corporation | Improved electrochemical cell |
DE19714674A1 (en) | 1997-04-09 | 1998-10-15 | Lre Technology Partner Gmbh | Test strip pack and measuring device for using one |
US5885839A (en) | 1997-04-15 | 1999-03-23 | Lxn Corporation | Methods of determining initiation and variable end points for measuring a chemical reaction |
US6103536A (en) | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
TW344029B (en) | 1997-05-02 | 1998-11-01 | Nat Science Council | Electrochemical sensor for measuring the concentration of hydrogen peroxide and precursor of hydrogen peroxide in liquid and method therefor |
US6391645B1 (en) | 1997-05-12 | 2002-05-21 | Bayer Corporation | Method and apparatus for correcting ambient temperature effect in biosensors |
US5798031A (en) | 1997-05-12 | 1998-08-25 | Bayer Corporation | Electrochemical biosensor |
US5921925A (en) | 1997-05-30 | 1999-07-13 | Ndm, Inc. | Biomedical electrode having a disposable electrode and a reusable leadwire adapter that interfaces with a standard leadwire connector |
GB9824627D0 (en) | 1998-11-11 | 1999-01-06 | Cambridge Sensors Ltd | Test strips for small volumes |
US6040195A (en) | 1997-06-10 | 2000-03-21 | Home Diagnostics, Inc. | Diagnostic sanitary test strip |
US6013459A (en) * | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
US6168957B1 (en) * | 1997-06-25 | 2001-01-02 | Lifescan, Inc. | Diagnostic test strip having on-strip calibration |
US6309526B1 (en) | 1997-07-10 | 2001-10-30 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
EP2006669A3 (en) | 1997-07-22 | 2008-12-31 | Kyoto Daiichi Kagaku Co., Ltd. | Concentration measuring apparatus and test strip for the concentration measuring apparatus |
JP3297630B2 (en) | 1997-07-28 | 2002-07-02 | 松下電器産業株式会社 | Biosensor |
JP3375040B2 (en) | 1997-07-29 | 2003-02-10 | 松下電器産業株式会社 | Substrate quantification method |
CA2244332C (en) | 1997-07-30 | 2002-04-02 | Becton, Dickinson And Company | Bonding agent and method of bonding electrode to printed conductive trace |
AUPO855897A0 (en) | 1997-08-13 | 1997-09-04 | Usf Filtration And Separations Group Inc. | Automatic analysing apparatus II |
US6121050A (en) | 1997-08-29 | 2000-09-19 | Han; Chi-Neng Arthur | Analyte detection systems |
US6061128A (en) | 1997-09-04 | 2000-05-09 | Avocet Medical, Inc. | Verification device for optical clinical assay systems |
US6129823A (en) | 1997-09-05 | 2000-10-10 | Abbott Laboratories | Low volume electrochemical sensor |
US6071391A (en) | 1997-09-12 | 2000-06-06 | Nok Corporation | Enzyme electrode structure |
US6259937B1 (en) | 1997-09-12 | 2001-07-10 | Alfred E. Mann Foundation | Implantable substrate sensor |
US6007775A (en) | 1997-09-26 | 1999-12-28 | University Of Washington | Multiple analyte diffusion based chemical sensor |
WO1999017117A1 (en) | 1997-09-30 | 1999-04-08 | Amira Medical | Analytical device with capillary reagent carrier |
US6088608A (en) | 1997-10-20 | 2000-07-11 | Alfred E. Mann Foundation | Electrochemical sensor and integrity tests therefor |
FI107080B (en) | 1997-10-27 | 2001-05-31 | Nokia Mobile Phones Ltd | measuring device |
KR100729585B1 (en) | 1997-10-31 | 2007-06-19 | 아로노위츠, 잭 엘 | Reflectometer |
US6102872A (en) | 1997-11-03 | 2000-08-15 | Pacific Biometrics, Inc. | Glucose detector and method |
US6044285A (en) | 1997-11-12 | 2000-03-28 | Lightouch Medical, Inc. | Method for non-invasive measurement of an analyte |
NZ504768A (en) | 1997-11-28 | 2002-11-26 | Provalis Diagnostics Ltd | Device and apparatus for conducting an assay |
CA2547299C (en) | 1997-12-04 | 2009-03-03 | Roche Diagnostics Corporation | Instrument and method |
US6579690B1 (en) | 1997-12-05 | 2003-06-17 | Therasense, Inc. | Blood analyte monitoring through subcutaneous measurement |
US5997817A (en) * | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
EP1038176B1 (en) | 1997-12-19 | 2003-11-12 | Amira Medical | Embossed test strip system |
US7407811B2 (en) | 1997-12-22 | 2008-08-05 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC excitation |
ES2326145T3 (en) * | 1997-12-22 | 2009-10-01 | Roche Diagnostics Operations, Inc. | Measuring device. |
US5971923A (en) | 1997-12-31 | 1999-10-26 | Acuson Corporation | Ultrasound system and method for interfacing with peripherals |
US6262749B1 (en) | 1997-12-31 | 2001-07-17 | Acuson Corporation | Ultrasonic system and method for data transfer, storage and/or processing |
JP3848993B2 (en) | 1998-01-06 | 2006-11-22 | アークレイ株式会社 | Method and apparatus for measuring the amount of components in the presence of coexisting substances |
US6485905B2 (en) | 1998-02-02 | 2002-11-26 | Signature Bioscience, Inc. | Bio-assay device |
US6394952B1 (en) | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
JP3978489B2 (en) * | 1998-02-26 | 2007-09-19 | アークレイ株式会社 | Blood measuring device |
US6206282B1 (en) | 1998-03-03 | 2001-03-27 | Pyper Products Corporation | RF embedded identification device |
US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
US6475360B1 (en) | 1998-03-12 | 2002-11-05 | Lifescan, Inc. | Heated electrochemical cell |
US6878251B2 (en) | 1998-03-12 | 2005-04-12 | Lifescan, Inc. | Heated electrochemical cell |
US6587705B1 (en) | 1998-03-13 | 2003-07-01 | Lynn Kim | Biosensor, iontophoretic sampling system, and methods of use thereof |
US5939609A (en) | 1998-03-23 | 1999-08-17 | Conception Technology Incorporated | Multi-use sensor having a controllable number of measurement cycles |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
WO1999051974A1 (en) | 1998-04-02 | 1999-10-14 | Matsushita Electric Industrial Co., Ltd. | Substrate determining method |
US6246966B1 (en) | 1998-04-06 | 2001-06-12 | Bayer Corporation | Method and apparatus for data management authentication in a clinical analyzer |
US5995236A (en) | 1998-04-13 | 1999-11-30 | Mit Development Corporation | Blood fluid characteristics analysis instrument |
US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US6271044B1 (en) | 1998-05-06 | 2001-08-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method and kit for detecting an analyte |
GB2337122B (en) | 1998-05-08 | 2002-11-13 | Medisense Inc | Test strip |
EP1077634B1 (en) | 1998-05-13 | 2003-07-30 | Cygnus, Inc. | Monitoring of physiological analytes |
ATE246356T1 (en) | 1998-05-13 | 2003-08-15 | Cygnus Therapeutic Systems | DEVICE FOR PREDICTING PHYSIOLOGICAL MEASUREMENTS |
US6526298B1 (en) * | 1998-05-18 | 2003-02-25 | Abbott Laboratories | Method for the non-invasive determination of analytes in a selected volume of tissue |
DE29809191U1 (en) | 1998-05-20 | 1998-08-13 | Lre Technology Partner Gmbh | Test strip measuring system |
WO1999060391A1 (en) | 1998-05-20 | 1999-11-25 | Arkray, Inc. | Method and apparatus for electrochemical measurement using statistical technique |
US6246330B1 (en) | 1998-05-29 | 2001-06-12 | Wyn Y. Nielsen | Elimination-absorber monitoring system |
US6287595B1 (en) | 1998-06-10 | 2001-09-11 | Delsys Pharmaceuticals Corporation | Biomedical assay device |
US6077660A (en) | 1998-06-10 | 2000-06-20 | Abbott Laboratories | Diagnostic assay requiring a small sample of biological fluid |
JP3389106B2 (en) * | 1998-06-11 | 2003-03-24 | 松下電器産業株式会社 | Electrochemical analysis element |
JP3874321B2 (en) | 1998-06-11 | 2007-01-31 | 松下電器産業株式会社 | Biosensor |
US6022366A (en) | 1998-06-11 | 2000-02-08 | Stat Medical Devices Inc. | Lancet having adjustable penetration depth |
US6294281B1 (en) * | 1998-06-17 | 2001-09-25 | Therasense, Inc. | Biological fuel cell and method |
WO1999067019A1 (en) * | 1998-06-24 | 1999-12-29 | Therasense, Inc. | Combinatorial electrochemical syntheses |
WO1999067628A1 (en) | 1998-06-24 | 1999-12-29 | Therasense, Inc. | Multi-sensor array for electrochemical recognition of nucleotide sequences and methods |
JP2000019147A (en) | 1998-07-01 | 2000-01-21 | Nok Corp | Reaction product measuring device |
US6656702B1 (en) | 1998-07-03 | 2003-12-02 | Matsushita Electric Industrial Co., Ltd. | Biosensor containing glucose dehydrogenase |
GB2339615B (en) | 1998-07-14 | 2001-02-07 | Cozart Bioscience Ltd | Screening device and method of screening an immunoassay test |
US6261519B1 (en) | 1998-07-20 | 2001-07-17 | Lifescan, Inc. | Medical diagnostic device with enough-sample indicator |
US6521182B1 (en) * | 1998-07-20 | 2003-02-18 | Lifescan, Inc. | Fluidic device for medical diagnostics |
US6162397A (en) | 1998-08-13 | 2000-12-19 | Lifescan, Inc. | Visual blood glucose test strip |
US6096186A (en) | 1998-08-18 | 2000-08-01 | Industrial Scientific Corporation | Method for determining exhaustion of an electrochemical gas sensor |
DE29814997U1 (en) | 1998-08-20 | 1998-12-03 | Lre Technology Partner Gmbh | Test strip measuring system |
US6638716B2 (en) | 1998-08-24 | 2003-10-28 | Therasense, Inc. | Rapid amperometric verification of PCR amplification of DNA |
US6251260B1 (en) | 1998-08-24 | 2001-06-26 | Therasense, Inc. | Potentiometric sensors for analytic determination |
US6281006B1 (en) | 1998-08-24 | 2001-08-28 | Therasense, Inc. | Electrochemical affinity assay |
ES2306525T3 (en) | 1998-08-26 | 2008-11-01 | Sensors For Medicine And Science, Inc. | OPTICAL-BASED DETECTION DEVICES. |
US6087182A (en) | 1998-08-27 | 2000-07-11 | Abbott Laboratories | Reagentless analysis of biological samples |
US5902731A (en) | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
US6180416B1 (en) * | 1998-09-30 | 2001-01-30 | Cygnus, Inc. | Method and device for predicting physiological values |
DE69908602T2 (en) | 1998-09-30 | 2004-06-03 | Cygnus, Inc., Redwood City | METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL MEASUREMENTS |
US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6136610A (en) | 1998-11-23 | 2000-10-24 | Praxsys Biosystems, Inc. | Method and apparatus for performing a lateral flow assay |
US6126609A (en) | 1998-11-23 | 2000-10-03 | Keith & Rumph Inventors, Inc. | Apparatus for taking blood samples from a patient |
GB9825992D0 (en) | 1998-11-28 | 1999-01-20 | Moorlodge Biotech Ventures Lim | Electrochemical sensor |
US6377894B1 (en) | 1998-11-30 | 2002-04-23 | Abbott Laboratories | Analyte test instrument having improved calibration and communication processes |
US6128519A (en) | 1998-12-16 | 2000-10-03 | Pepex Biomedical, Llc | System and method for measuring a bioanalyte such as lactate |
EP1010894B1 (en) | 1998-12-19 | 2004-03-03 | GARDENA Kress + Kastner GmbH | Pond insert with pump |
US6203952B1 (en) | 1999-01-14 | 2001-03-20 | 3M Innovative Properties Company | Imaged article on polymeric substrate |
US6344490B1 (en) * | 1999-01-22 | 2002-02-05 | Exxon Research And Engineering Company | Removable filter for slurry hydrocarbon synthesis process |
DE59900131D1 (en) | 1999-01-23 | 2001-07-26 | Ident Gmbh X | RFID transponder with printable surface |
US6565738B1 (en) | 1999-01-28 | 2003-05-20 | Abbott Laboratories | Diagnostic test for the measurement of analyte in abiological fluid |
US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
US6197040B1 (en) | 1999-02-23 | 2001-03-06 | Lifescan, Inc. | Lancing device having a releasable connector |
US6045567A (en) | 1999-02-23 | 2000-04-04 | Lifescan Inc. | Lancing device causing reduced pain |
GB2347746A (en) | 1999-03-05 | 2000-09-13 | Azur Env Ltd | Detecting analytes, particularly nucleic acids, in a sample |
US6333019B1 (en) | 1999-04-29 | 2001-12-25 | Marc-Olivier Coppens | Method for operating a chemical and/or physical process by means of a hierarchical fluid injection system |
US6150124A (en) | 1999-05-20 | 2000-11-21 | Umm Electronics, Inc. | Method for passively determining the application of a sample fluid on an analyte strip |
US6287451B1 (en) | 1999-06-02 | 2001-09-11 | Handani Winarta | Disposable sensor and method of making |
US6258229B1 (en) | 1999-06-02 | 2001-07-10 | Handani Winarta | Disposable sub-microliter volume sensor and method of making |
US6193873B1 (en) * | 1999-06-15 | 2001-02-27 | Lifescan, Inc. | Sample detection to initiate timing of an electrochemical assay |
JP4801301B2 (en) | 1999-06-18 | 2011-10-26 | アボット ダイアベティス ケア インコーポレイテッド | In vivo analyte sensor with limited mass transfer |
US6514769B2 (en) * | 1999-07-29 | 2003-02-04 | Jin Po Lee | Multiple analyte assay device with sample integrity monitoring system |
CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
DE19936693A1 (en) * | 1999-08-04 | 2001-02-08 | Lre Technology Partner Gmbh | Instrument for the measurement of blood sugar concentrations has a test field with electrodes for the test strip and a circuit for measurement/evaluation of the current strength for display |
US6352633B1 (en) | 1999-08-31 | 2002-03-05 | Spectrumedix Corporation | Automated parallel capillary electrophoresis system with hydrodynamic sample injection |
EP1130390A1 (en) | 1999-09-13 | 2001-09-05 | Matsushita Electric Industrial Co., Ltd. | Process for producing lipid-modified enzyme and biosensor |
US6645359B1 (en) | 2000-10-06 | 2003-11-11 | Roche Diagnostics Corporation | Biosensor |
US7276146B2 (en) | 2001-11-16 | 2007-10-02 | Roche Diagnostics Operations, Inc. | Electrodes, methods, apparatuses comprising micro-electrode arrays |
US6662439B1 (en) | 1999-10-04 | 2003-12-16 | Roche Diagnostics Corporation | Laser defined features for patterned laminates and electrodes |
DE60024965T2 (en) | 1999-10-05 | 2006-07-13 | Matsushita Electric Industrial Co., Ltd., Kadoma | GLUCOSE SENSOR |
US6136549A (en) | 1999-10-15 | 2000-10-24 | Feistel; Christopher C. | systems and methods for performing magnetic chromatography assays |
US6283982B1 (en) | 1999-10-19 | 2001-09-04 | Facet Technologies, Inc. | Lancing device and method of sample collection |
US6218571B1 (en) | 1999-10-27 | 2001-04-17 | Lifescan, Inc. | 8-(anilino)-1-naphthalenesulfonate analogs |
US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
US6923894B2 (en) | 1999-11-11 | 2005-08-02 | Apex Biotechnology Corporation | Biosensor with multiple sampling ways |
AU1607801A (en) | 1999-11-15 | 2001-05-30 | Therasense, Inc. | Transition metal complexes with bidentate ligand having an imidazole ring |
DE60025751T2 (en) | 1999-11-15 | 2006-10-12 | Arkray, Inc. | BIOSENSOR |
CN1632553A (en) | 1999-11-15 | 2005-06-29 | 松下电器产业株式会社 | Biosensor, method of forming thin-film electrode, and method and apparatus for quantitative determination |
DE60029127T2 (en) | 1999-11-16 | 2007-05-31 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSOR |
CN1187609C (en) * | 1999-11-22 | 2005-02-02 | 松下电器产业株式会社 | Cholesterol sensor and method for determining cholesterol |
JP4050434B2 (en) | 1999-11-29 | 2008-02-20 | 松下電器産業株式会社 | Sample discrimination method |
JP2001159618A (en) * | 1999-12-03 | 2001-06-12 | Matsushita Electric Ind Co Ltd | Biosensor |
US6413395B1 (en) | 1999-12-16 | 2002-07-02 | Roche Diagnostics Corporation | Biosensor apparatus |
US6316264B1 (en) | 1999-12-17 | 2001-11-13 | Bayer Corporation | Test strip for the assay of an analyte in a liquid sample |
US6541216B1 (en) | 1999-12-22 | 2003-04-01 | Roche Diagnostics Corporation | Amperometric biosensor test strip |
US6627057B1 (en) | 1999-12-23 | 2003-09-30 | Roche Diagnostic Corporation | Microsphere containing sensor |
ES2238254T3 (en) | 1999-12-27 | 2005-09-01 | Matsushita Electric Industrial Co., Ltd. | BIOSENSOR |
JP2001183330A (en) | 1999-12-27 | 2001-07-06 | Matsushita Electric Ind Co Ltd | Biosensor |
JP3982133B2 (en) | 2000-01-25 | 2007-09-26 | 松下電器産業株式会社 | Measuring device using biosensor and biosensor and dedicated standard solution used therefor |
US6485923B1 (en) | 2000-02-02 | 2002-11-26 | Lifescan, Inc. | Reagent test strip for analyte determination having hemolyzing agent |
US6716577B1 (en) | 2000-02-02 | 2004-04-06 | Lifescan, Inc. | Electrochemical test strip for use in analyte determination |
WO2001061341A1 (en) | 2000-02-18 | 2001-08-23 | Matsushita Electric Industrial Co., Ltd. | Measuring system |
EP1172651B1 (en) | 2000-02-18 | 2015-07-15 | Panasonic Healthcare Co., Ltd. | Measuring system |
US6792791B2 (en) | 2000-02-18 | 2004-09-21 | Matsushita Electric Industrial Co., Ltd. | Inspection chip for sensor measuring instrument |
US6538735B1 (en) | 2000-02-25 | 2003-03-25 | Packard Instrument Company | Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells |
US6706159B2 (en) | 2000-03-02 | 2004-03-16 | Diabetes Diagnostics | Combined lancet and electrochemical analyte-testing apparatus |
JP3985417B2 (en) | 2000-03-08 | 2007-10-03 | 松下電器産業株式会社 | Biosensor and manufacturing method thereof |
GB0005564D0 (en) | 2000-03-08 | 2000-05-03 | Inverness Medical Ltd | Measurjement of substances in liquid |
KR100340173B1 (en) | 2000-03-22 | 2002-06-12 | 이동준 | Electrochemical Biosensor Readout Meter |
AU2001228915A1 (en) | 2000-03-22 | 2001-10-03 | All Medicus Co., Ltd. | Electrochemical biosensor test strip with recognition electrode and readout meter using this test strip |
DE10014724A1 (en) | 2000-03-24 | 2001-09-27 | Endress Hauser Gmbh Co | Liquid level and density monitoring method employed in food, chemical industry, involves evaluating vibration of vibrating rods arranged immersed in liquid at two different modes and recognizing mass change in rods |
US6571651B1 (en) | 2000-03-27 | 2003-06-03 | Lifescan, Inc. | Method of preventing short sampling of a capillary or wicking fill device |
US6612111B1 (en) | 2000-03-27 | 2003-09-02 | Lifescan, Inc. | Method and device for sampling and analyzing interstitial fluid and whole blood samples |
US20020092612A1 (en) | 2000-03-28 | 2002-07-18 | Davies Oliver William Hardwicke | Rapid response glucose sensor |
EP1268849A2 (en) | 2000-03-28 | 2003-01-02 | Lifescan, Inc. | Reagents and methods for detecting a reduced cofactor |
WO2001073109A2 (en) * | 2000-03-28 | 2001-10-04 | Diabetes Diagnostics, Inc. | Continuous process for manufacture of disposable electro-chemical sensor |
DK1269173T3 (en) | 2000-03-28 | 2005-11-14 | Diabetes Diagnostics Inc | Glucose sensor with fast response |
US6911131B2 (en) | 2000-03-29 | 2005-06-28 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
JP2001281197A (en) | 2000-03-30 | 2001-10-10 | Matsushita Electric Ind Co Ltd | Biosensor measuring apparatus |
US6488827B1 (en) | 2000-03-31 | 2002-12-03 | Lifescan, Inc. | Capillary flow control in a medical diagnostic device |
WO2001075438A2 (en) | 2000-03-31 | 2001-10-11 | Lifescan, Inc. | Electrically-conductive patterns for monitoring the filling of medical devices |
US6858433B1 (en) | 2000-04-03 | 2005-02-22 | Roche Diagnostics Operations, Inc. | Biosensor electromagnetic noise cancellation |
US6623501B2 (en) | 2000-04-05 | 2003-09-23 | Therasense, Inc. | Reusable ceramic skin-piercing device |
CA2406133A1 (en) | 2000-04-17 | 2001-10-25 | Rashid Bashir | Biosensor and related method |
US6413213B1 (en) | 2000-04-18 | 2002-07-02 | Roche Diagnostics Corporation | Subscription based monitoring system and method |
JP4061816B2 (en) | 2000-04-27 | 2008-03-19 | 松下電器産業株式会社 | Biosensor |
IT1314759B1 (en) | 2000-05-08 | 2003-01-03 | Menarini Farma Ind | INSTRUMENTATION FOR MEASUREMENT AND CONTROL OF THE CONTENT OF GLUCOSIOLACTATE OR OTHER METABOLITES IN BIOLOGICAL FLUIDS |
JP4562854B2 (en) | 2000-05-08 | 2010-10-13 | パナソニック株式会社 | Chromatographic measurement method |
AU2001263022A1 (en) | 2000-05-12 | 2001-11-26 | Therasense, Inc. | Electrodes with multilayer membranes and methods of using and making the electrodes |
EP1156302B1 (en) | 2000-05-15 | 2004-09-29 | Krohne Messtechnik Gmbh & Co. Kg | Level measuring device |
US6557427B2 (en) * | 2000-05-24 | 2003-05-06 | Micronics, Inc. | Capillaries for fluid movement within microfluidic channels |
WO2001090754A1 (en) | 2000-05-26 | 2001-11-29 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
DE60111904T2 (en) | 2000-05-29 | 2006-04-20 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSOR AND METHOD FOR THE PRODUCTION THEREOF |
WO2001092886A1 (en) | 2000-06-01 | 2001-12-06 | Matsushita Electric Industrial Co., Ltd. | Biosensor and blood component analyzing method |
TW548095B (en) * | 2000-06-01 | 2003-08-21 | Chih-Hui Lee | Electrochemical electrode test piece and method for producing the same |
WO2002000112A2 (en) | 2000-06-26 | 2002-01-03 | Boston Medical Technologies, Inc. | Glucose metering system |
US7112451B2 (en) | 2000-06-28 | 2006-09-26 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
DE10032775B4 (en) * | 2000-07-06 | 2007-06-14 | Endress + Hauser Gmbh + Co. Kg | Device for determining and / or monitoring the fill level of a product in a container |
US6561989B2 (en) * | 2000-07-10 | 2003-05-13 | Bayer Healthcare, Llc | Thin lance and test sensor having same |
US6444115B1 (en) | 2000-07-14 | 2002-09-03 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
GB0017737D0 (en) | 2000-07-20 | 2000-09-06 | Hypoguard Limited | Test device |
US6833110B2 (en) | 2000-07-20 | 2004-12-21 | Hypoguard Limited | Test member |
GB2365123A (en) | 2000-07-20 | 2002-02-13 | Hypoguard Ltd | Test strip |
JP4177662B2 (en) * | 2000-07-24 | 2008-11-05 | 松下電器産業株式会社 | Biosensor |
WO2002010734A1 (en) | 2000-07-31 | 2002-02-07 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
WO2002010735A1 (en) | 2000-07-31 | 2002-02-07 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
PL365675A1 (en) | 2000-07-31 | 2005-01-10 | Lifescan, Inc. | Method and apparatus for detecting the presence of a fluid on a test strip |
GB0019694D0 (en) | 2000-08-11 | 2000-09-27 | Cambridge Sensors Ltd | Electrochemical strip test for small volumes |
JP3913454B2 (en) | 2000-08-29 | 2007-05-09 | 株式会社リガク | Measuring method of surface leakage current of sample |
US6420128B1 (en) | 2000-09-12 | 2002-07-16 | Lifescan, Inc. | Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same |
US6555061B1 (en) | 2000-10-05 | 2003-04-29 | Lifescan, Inc. | Multi-layer reagent test strip |
US6540890B1 (en) | 2000-11-01 | 2003-04-01 | Roche Diagnostics Corporation | Biosensor |
US7232510B2 (en) | 2000-11-30 | 2007-06-19 | Matsushita Electric Industrial Co., Ltd. | Biosensor, measuring instrument for biosensor, and method of quantifying substrate |
US6967105B2 (en) | 2000-12-02 | 2005-11-22 | Queststar Medical, Inc. | Surface-modified wick for diagnostic test strip |
US6447657B1 (en) | 2000-12-04 | 2002-09-10 | Roche Diagnostics Corporation | Biosensor |
DE60125594T2 (en) * | 2000-12-04 | 2007-10-11 | Kubota Corp. | AIR DISTRIBUTION AND SPILLING PROCESS THEREFOR |
US6800488B2 (en) | 2000-12-13 | 2004-10-05 | Lifescan, Inc. | Methods of manufacturing reagent test strips |
GB0030929D0 (en) | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
US6558528B1 (en) | 2000-12-20 | 2003-05-06 | Lifescan, Inc. | Electrochemical test strip cards that include an integral dessicant |
JP4183902B2 (en) | 2000-12-27 | 2008-11-19 | 松下電器産業株式会社 | Biosensor |
US6512986B1 (en) * | 2000-12-30 | 2003-01-28 | Lifescan, Inc. | Method for automated exception-based quality control compliance for point-of-care devices |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
RU2180514C1 (en) | 2001-01-15 | 2002-03-20 | ШМЕЛЕВ Владимир Михайлович | Method for determining glucose concentration in noninvasive way |
CN1486423A (en) * | 2001-01-17 | 2004-03-31 | ������������ʽ���� | Quantitative analyzing method and quantitative analyzer using sensor |
CN1471373A (en) | 2001-02-05 | 2004-01-28 | ��³��ɭ˹��˾ | Methods of determining concentration of glucose in blood |
US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
US6525330B2 (en) * | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
US20020133064A1 (en) | 2001-03-14 | 2002-09-19 | Matsushita Electric Industrial Co., Ltd. | Blood sugar lever measuring device and semiconductor integrated circuit |
US6576102B1 (en) | 2001-03-23 | 2003-06-10 | Virotek, L.L.C. | Electrochemical sensor and method thereof |
US7124095B2 (en) | 2001-03-26 | 2006-10-17 | International Business Machines Corporation | Third party merchandise return method, storage medium and implementing system |
CN100339044C (en) | 2001-03-29 | 2007-09-26 | 因弗内斯医疗有限公司 | Integrated measuring apparatus for testing samples |
US7041468B2 (en) | 2001-04-02 | 2006-05-09 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
CN100401050C (en) * | 2001-04-16 | 2008-07-09 | 松下电器产业株式会社 | Biosensor |
DE10123259A1 (en) | 2001-05-12 | 2002-11-21 | Eppendorf Ag | Microfluidic storage and / or dosing component |
JP3621084B2 (en) | 2001-05-15 | 2005-02-16 | 松下電器産業株式会社 | Biosensor |
US6932894B2 (en) | 2001-05-15 | 2005-08-23 | Therasense, Inc. | Biosensor membranes composed of polymers containing heterocyclic nitrogens |
US6491803B1 (en) | 2001-05-18 | 2002-12-10 | Apex Biotechnology Corporation | Test strip and biosensor incorporating with nanometer metal particles |
AU784254B2 (en) * | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
JP4213361B2 (en) | 2001-05-22 | 2009-01-21 | パナソニック株式会社 | Biosensor |
US6549796B2 (en) | 2001-05-25 | 2003-04-15 | Lifescan, Inc. | Monitoring analyte concentration using minimally invasive devices |
EP1288654B1 (en) | 2001-05-29 | 2008-10-22 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
US6960287B2 (en) | 2001-06-11 | 2005-11-01 | Bayer Corporation | Underfill detection system for a test sensor |
US6501976B1 (en) | 2001-06-12 | 2002-12-31 | Lifescan, Inc. | Percutaneous biological fluid sampling and analyte measurement devices and methods |
EP1398626A4 (en) | 2001-06-14 | 2004-09-22 | Matsushita Electric Ind Co Ltd | Biosensor |
US6576416B2 (en) | 2001-06-19 | 2003-06-10 | Lifescan, Inc. | Analyte measurement device and method of use |
KR100426638B1 (en) * | 2001-07-07 | 2004-04-08 | 주식회사 인포피아 | Glucose strip sensor and glucose measurement method by the strip sensor |
CA2451705A1 (en) | 2001-07-13 | 2003-01-23 | Exxonmobil Research And Engineering Company | Direct production of high purity fischer-tropsch wax |
US6767441B1 (en) | 2001-07-31 | 2004-07-27 | Nova Biomedical Corporation | Biosensor with peroxidase enzyme |
EP1413879B1 (en) | 2001-08-01 | 2012-01-25 | ARKRAY, Inc. | Analyzing instrument, analyzing device |
US20030036202A1 (en) * | 2001-08-01 | 2003-02-20 | Maria Teodorcyzk | Methods and devices for use in analyte concentration determination assays |
JP4383860B2 (en) | 2001-08-09 | 2009-12-16 | パナソニック株式会社 | Biosensor and measurement method |
US20030190690A1 (en) | 2001-08-10 | 2003-10-09 | Mie Takahashi | Biosensor and method for analyzing blood components using it |
US6814844B2 (en) | 2001-08-29 | 2004-11-09 | Roche Diagnostics Corporation | Biosensor with code pattern |
US7052591B2 (en) | 2001-09-21 | 2006-05-30 | Therasense, Inc. | Electrodeposition of redox polymers and co-electrodeposition of enzymes by coordinative crosslinking |
WO2003029804A1 (en) | 2001-09-28 | 2003-04-10 | Arkray, Inc. | Measurement instrument and concentration measurement apparatus |
WO2003030731A2 (en) | 2001-10-09 | 2003-04-17 | Optiscan Biomedical Corporation | Method and apparatus for improving clinical accuracy of analyte measurements |
US6797150B2 (en) | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
CN1920548B (en) | 2001-10-10 | 2013-05-29 | 生命扫描有限公司 | Method for manufacturing electrochemical cell |
US7048262B2 (en) | 2001-11-01 | 2006-05-23 | Praxair Technology, Inc. | Method and apparatus for injecting oxygen into fermentation processes |
US6717024B2 (en) | 2001-11-06 | 2004-04-06 | Exxonmobil Research And Engineering Company | Slurry hydrocarbon synthesis with liquid hydroisomerization in the synthesis reactor |
EP1452857A4 (en) | 2001-11-14 | 2006-05-24 | Matsushita Electric Ind Co Ltd | Biosensor |
JPWO2003042679A1 (en) | 2001-11-14 | 2005-03-10 | 松下電器産業株式会社 | Biosensor |
US6872298B2 (en) | 2001-11-20 | 2005-03-29 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
AU2002346486A1 (en) | 2001-11-21 | 2003-06-10 | James R. Braig | Method for adjusting a blood analyte measurement |
US6749887B1 (en) | 2001-11-28 | 2004-06-15 | Lifescan, Inc. | Solution drying system |
US6689411B2 (en) | 2001-11-28 | 2004-02-10 | Lifescan, Inc. | Solution striping system |
US6872299B2 (en) | 2001-12-10 | 2005-03-29 | Lifescan, Inc. | Passive sample detection to initiate timing of an assay |
US6856125B2 (en) | 2001-12-12 | 2005-02-15 | Lifescan, Inc. | Biosensor apparatus and method with sample type and volume detection |
EP1466008A2 (en) | 2002-01-15 | 2004-10-13 | Agamatrix, Inc. | Method and apparatus for processing electrochemical signals |
US6863800B2 (en) | 2002-02-01 | 2005-03-08 | Abbott Laboratories | Electrochemical biosensor strip for analysis of liquid samples |
US7601249B2 (en) | 2002-02-10 | 2009-10-13 | Agamatrix, Inc. | Method and apparatus for assay of electrochemical properties |
DE10206824B4 (en) | 2002-02-18 | 2005-04-28 | Kautex Textron Gmbh & Co Kg | Method for optical level determination in liquid-filled containers |
US7085039B2 (en) | 2002-03-15 | 2006-08-01 | Tyco Telecommunications (Us) Inc. | Hybrid Raman/erbium-doped fiber amplifier and transmission system with dispersion map |
GB2390602A (en) | 2002-04-02 | 2004-01-14 | Inverness Medical Ltd | Test strip dispenser vial and cassette |
GB2388898B (en) | 2002-04-02 | 2005-10-05 | Inverness Medical Ltd | Integrated sample testing meter |
US6909791B2 (en) | 2002-04-03 | 2005-06-21 | General Phosphorix, Llc | Method of measuring a line edge roughness of micro objects in scanning microscopes |
US7226461B2 (en) | 2002-04-19 | 2007-06-05 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release |
US6743635B2 (en) * | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
US6946299B2 (en) * | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
US20030143113A2 (en) | 2002-05-09 | 2003-07-31 | Lifescan, Inc. | Physiological sample collection devices and methods of using the same |
CN1467496A (en) | 2002-06-03 | 2004-01-14 | 松下电器产业株式会社 | Biosensor |
DE10397018A5 (en) | 2002-07-02 | 2015-05-28 | Panasonic Healthcare Holdings Co., Ltd. | Biosensor, biosensor chip and biosensor device |
US7244264B2 (en) | 2002-12-03 | 2007-07-17 | Roche Diagnostics Operations, Inc. | Dual blade lancing test strip |
US6797039B2 (en) | 2002-12-27 | 2004-09-28 | Dwain F. Spencer | Methods and systems for selectively separating CO2 from a multicomponent gaseous stream |
US7452457B2 (en) * | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US7488601B2 (en) * | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
US7429865B2 (en) | 2005-10-05 | 2008-09-30 | Roche Diagnostics Operations, Inc. | Method and system for error checking an electrochemical sensor |
-
2003
- 2003-10-17 US US10/687,958 patent/US7452457B2/en active Active
-
2004
- 2004-06-18 EP EP04776822.1A patent/EP1639355B1/en active Active
- 2004-06-18 JP JP2006517472A patent/JP4681546B2/en active Active
- 2004-06-18 CA CA2714309A patent/CA2714309C/en active Active
- 2004-06-18 WO PCT/US2004/019721 patent/WO2005008231A1/en active Search and Examination
- 2004-06-18 CA CA2530052A patent/CA2530052C/en active Active
- 2004-06-18 CA CA2814802A patent/CA2814802C/en active Active
-
2008
- 2008-10-20 US US12/254,515 patent/US8663442B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2530052C (en) | 2010-11-30 |
US8663442B2 (en) | 2014-03-04 |
CA2814802C (en) | 2016-05-24 |
US7452457B2 (en) | 2008-11-18 |
US20090045076A1 (en) | 2009-02-19 |
US20040256248A1 (en) | 2004-12-23 |
CA2714309C (en) | 2013-08-06 |
CA2814802A1 (en) | 2005-01-27 |
JP2007524826A (en) | 2007-08-30 |
WO2005008231A1 (en) | 2005-01-27 |
EP1639355B1 (en) | 2020-10-07 |
JP4681546B2 (en) | 2011-05-11 |
CA2714309A1 (en) | 2005-01-27 |
EP1639355A1 (en) | 2006-03-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2530052A1 (en) | System and method for analyte measurement using dose sufficiency electrodes | |
CA1137553A (en) | Liquid transport device containing means for delaying capillary flow | |
KR101518313B1 (en) | Method for determination of analyte concentrations | |
CN102308203B (en) | Blood clotting system analytical equipment and the method for analyzing blood coagulation system | |
JP4374020B2 (en) | Analyte measurement system and method using AC excitation | |
Zheng et al. | Microfluidic characterization of specific membrane capacitance and cytoplasm conductivity of singlecells | |
RU2000115708A (en) | METHOD FOR MEASURING CONCENTRATION OF ANALYZED SUBSTANCE (OPTIONS), MEASURING INSTRUMENT FOR MEASURING CONCENTRATION OF ANALYZED SUBSTANCE | |
EP1893999B1 (en) | Methods and devices for controlling the impact of short circuit faults on co-planar electrochemical sensors | |
CA2553633C (en) | Fluid testing sensor having vents for directing fluid flow | |
RU2007117732A (en) | DETERMINATION OF CONCENTRATION IN THE DIFFUSION BARRIER LAYER | |
CA2529300A1 (en) | Devices and methods relating to electrochemical biosensors | |
ATE406571T1 (en) | TIMER WITH FAST RESPONSIVE GLUCOSE SENSOR | |
CZ20023332A3 (en) | Method of determining concentration in a liquid sample and apparatus for making the same | |
KR20080003419A (en) | Method and apparatus for detection of abnormal traces during electrochemical analyte detection | |
DE602004018695D1 (en) | Method for detecting distortion in enzyme electrode measurements | |
WO2008040990A3 (en) | Methods for determining an analyte concentration using signal processing algorithms | |
RU2002121247A (en) | Electrochemical method for the analysis of coagulation and device for its implementation | |
JP2010078614A (en) | System and method for determining abused sensor during analyte measurement in biological fluid | |
DE69630295D1 (en) | DIAGNOSTIC DEVICE AND METHOD | |
GB2450351A (en) | Monitoring the flow edge of a fluid across an immunoassay region | |
JP2017519226A (en) | Hemolysis detection method and system | |
KR20150131362A (en) | Descriptor-based methods of electrochemically measuring an analyte as well as devices, apparatuses and systems incoporating the same | |
US20150076009A1 (en) | Pulsed signal testing of biological fluid | |
RU2690065C2 (en) | Diffusion determining method | |
JP2005055446A (en) | Method of detecting gas bubbles in liquid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |