CA2530394A1 - Targeted tissue cooling within a body - Google Patents
Targeted tissue cooling within a body Download PDFInfo
- Publication number
- CA2530394A1 CA2530394A1 CA002530394A CA2530394A CA2530394A1 CA 2530394 A1 CA2530394 A1 CA 2530394A1 CA 002530394 A CA002530394 A CA 002530394A CA 2530394 A CA2530394 A CA 2530394A CA 2530394 A1 CA2530394 A1 CA 2530394A1
- Authority
- CA
- Canada
- Prior art keywords
- medical device
- patch
- tissue region
- distal end
- elongate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/10—Cooling bags, e.g. ice-bags
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
A medical device has a structure deployable from its distal end to cool a target tissue region inside the body, such as tissue within a chamber of the heart. Also, a method of cooling a target tissue region inside a body includes introducing a distal portion of a catheter having a deployable structure at a distal end into the body. The method also includes positioning the distal catheter portion near a target tissue region, deploying the deployable structure, and placing the deployed structure in contact with the target tissue region to cool the target tissue region.
Claims (39)
1. A medical device comprising:
an elongate body having a distal end for entry into a body and positionable near a target tissue region within the body; and a structure deployable from the distal end of the elongate body to cool the target tissue region.
an elongate body having a distal end for entry into a body and positionable near a target tissue region within the body; and a structure deployable from the distal end of the elongate body to cool the target tissue region.
2. The medical device of claim 1 wherein the elongate body comprises:
an elongate shaft that has the deployable structure affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable structure.
an elongate shaft that has the deployable structure affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable structure.
3. The medical device of claim 1 wherein the deployable structure comprises a patch having a surface shaped to contact the tissue region.
4. The medical device of claim 3 wherein the deployable patch has an inner chamber that receives, from a lumen in the elongate body, a fluid for cooling the patch surface that contacts the target tissue region.
5. The medical device of claim 1 wherein the deployable structure is cup-shaped and has a periphery for contacting body tissue to form a chamber whose bounds are defined by the body tissue and an inside surface of the cup-shaped structure.
6. The medical device of claim 1 wherein the deployable structure has an inner chamber with a Joule-Thompson orifice into the inner chamber so that a liquid supplied through the elongate body, through the orifice, and into the inner chamber has a phase change into a gas.
7. The medical device of claim 1 wherein the distal end of the device is advanceable through a body vessel to the target tissue region when the structure is in a non-deployed state.
8. The medical device of claim 7 wherein the structure cannot be advanced through the body vessel when the structure is in a deployed state.
9. The medical device of claim 1 wherein the elongate body further comprises a proximal end that remains outside the body when the distal end of the elongate body is positioned near the target tissue region.
10. A medical device comprising:
an elongate body having a distal end for entry into a body and positionable near a target tissue region within the body;
a patch deployable from the distal end of the elongate shaft to cool the target tissue region, the patch having a surface shaped to contact the target tissue region.
an elongate body having a distal end for entry into a body and positionable near a target tissue region within the body;
a patch deployable from the distal end of the elongate shaft to cool the target tissue region, the patch having a surface shaped to contact the target tissue region.
11. The medical device of claim 10 wherein the patch comprises a collapsible frame made of a shape memory alloy so that, when deployed, the patch expands to create the surface that contacts the target tissue region.
12. The medical device of claim 10 wherein the elongate body comprises:
an elongate shaft that has the deployable patch affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable patch.
an elongate shaft that has the deployable patch affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable patch.
13. The medical device of claim 12 wherein the patch is deployed from the distal end of the body by moving the sleeve proximally with respect to the shaft to expose the patch from the confines of the sleeve.
14. The medical device of claim 10 wherein the distal end of the device is advanceable through a body vessel to the tissue region when the patch is in a non-deployed state.
15. The medical device of claim 14 wherein the distal end of the device is not advanceable through the body vessel when the patch is in a deployed state.
16. The medical device of claim 10 wherein the elongate shaft comprises:
a first lumen to provide fluid to an inner chamber of the patch; and a second lumen to remove fluid from the inner chamber of the patch.
a first lumen to provide fluid to an inner chamber of the patch; and a second lumen to remove fluid from the inner chamber of the patch.
17. The medical device of claim 16 wherein the inner chamber of the patch comprises a conduit through which fluid flows, the conduit being located adjacent to the surface of the patch in contact with the target tissue region.
18. The medical device of claim 10 further comprising at least one additional patch deployable from the distal end of the elongate body.
19. The medical device of claim 10 wherein the patch comprises a thermoelectric cooling element positioned adjacent to the surface of the patch and in contact with the target tissue region that cools the target tissue region.
20. The medical device of claim 10 further comprising a balloon positioned adjacent to a surface of the patch that does not contact the target tissue region, the balloon providing insulation between the patch and body fluids when the patch is deployed and positioned near the target tissue region.
21. The medical device of claim 20 wherein the elongate body comprises a lumen to provide the balloon with an inflation medium.
22. The medical device of claim 20 further comprising an anchoring mechanism near the distal end of the elongate shaft that is connectable to tissues inside the body to anchor the patch when it is deployed near the target tissue area.
23. The medical device of claim 10 wherein the patch has an inner chamber with a Joule-Thompson orifice into the inner chamber so that a liquid supplied through the elongate shaft, through the orifice, and into the inner chamber has a phase change into a gas.
24. The medical device of claim 10 wherein the patch comprises a temperature sensor to sense the temperature of the surface of the patch in contact with the target tissue region.
25. A medical device comprising:
an elongate body having fluid transfer lumens extending longitudinally through the shaft to a distal end; and a cup-shaped structure deployable from the distal end of the body and having a periphery for contacting body tissue to form a chamber bound by the body tissue and an inside surface of the cup-shaped structure, the chamber being in fluid communication with the body fluid transfer lumens to allow fluid to be delivered to and from the chamber.
an elongate body having fluid transfer lumens extending longitudinally through the shaft to a distal end; and a cup-shaped structure deployable from the distal end of the body and having a periphery for contacting body tissue to form a chamber bound by the body tissue and an inside surface of the cup-shaped structure, the chamber being in fluid communication with the body fluid transfer lumens to allow fluid to be delivered to and from the chamber.
26. The medical device of claim 25 wherein the cup-shaped structure comprises a collapsible frame made of a shape memory alloy so that, when deployed, the cup-shaped structure can expand to take on a cup-shaped configuration.
27. The medical device of claim 25 wherein the elongate body comprises:
an elongate shaft that has the deployable structure affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable structure.
an elongate shaft that has the deployable structure affixed to its distal end;
and an elongate sleeve that is longitudinally movable with respect to the shaft, wherein the elongate sleeve, when moved distally, encompasses the deployable structure.
28. The medical device of claim 27 wherein the cup-shaped structure is deployed from the distal end of the body by moving the distal end of the sleeve proximally with respect to the shaft to expose the cup-shaped structure from the confines of the sleeve.
29. The medical device of claim 25 wherein the distal end of the device is advanceable through a body vessel to the tissue region when the cup-shaped structure is in a non-deployed state.
30. The medical device of claim 29 wherein the distal end of the device is not advanceable through the body vessel when the cup-shaped structure is in a deployed state.
31. The medical device of claim 25 wherein the periphery of the cup-shaped structure comprises small holes positioned to contact the body tissue, the holes securing the periphery of the cup-shaped structure to the body tissue when a vacuum is applied.
32. The device of claim 25 wherein the cup-shaped structure comprises a layered structure with an inflatable chamber positioned between first and second layers and inflatable to insulate body fluids from the fluid in the sealed chamber.
33. The device of claim 32 wherein the elongate shaft comprises a lumen to provide the inflatable chamber with an inflation medium.
34. The device of claim 25 further comprising a temperature sensor to sense the temperature of the fluid delivered to and from the chamber.
35. A method of cooling a target tissue region inside a body, the method comprising:
introducing into a body vessel a distal portion of a catheter having an elongate body and a structure deployable from a distal end of the elongate body;
positioning the distal portion of the catheter near the target tissue region;
deploying the deployable structure from the elongate body;
placing the deployed structure in contact with the target tissue region; and cooling the deployed structure to cool the target tissue region.
introducing into a body vessel a distal portion of a catheter having an elongate body and a structure deployable from a distal end of the elongate body;
positioning the distal portion of the catheter near the target tissue region;
deploying the deployable structure from the elongate body;
placing the deployed structure in contact with the target tissue region; and cooling the deployed structure to cool the target tissue region.
36. The method of claim 35 wherein the deployable structure comprises a patch having a surface shaped to contact the tissue region.
37. The method of claim 35 wherein the deployable structure is cup-shaped and has a periphery for contacting to the body tissue region to form a chamber bound by the body tissue and an inside surface of the cup.
38. The method of claim 35 wherein the target tissue region is within a chamber of the heart.
39. The method of claim 38 wherein the deploying of the deployable structure occurs after the distal end of the catheter is positioned inside the chamber of the heart.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/603,705 US20040267338A1 (en) | 2003-06-25 | 2003-06-25 | Targeted tissue cooling within a body |
| US10/603,705 | 2003-06-25 | ||
| PCT/US2004/019992 WO2005002478A2 (en) | 2003-06-25 | 2004-06-23 | Targeted tissue cooling within a body |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2530394A1 true CA2530394A1 (en) | 2005-01-13 |
| CA2530394C CA2530394C (en) | 2012-07-31 |
Family
ID=33539790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2530394A Expired - Fee Related CA2530394C (en) | 2003-06-25 | 2004-06-23 | Targeted tissue cooling within a body |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20040267338A1 (en) |
| EP (1) | EP1646342A2 (en) |
| JP (1) | JP4668182B2 (en) |
| CA (1) | CA2530394C (en) |
| WO (1) | WO2005002478A2 (en) |
Families Citing this family (16)
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|---|---|---|---|---|
| US20040167467A1 (en) * | 2003-02-21 | 2004-08-26 | Kent Harrison | Delivering cooled fluid to sites inside the body |
| US7963940B2 (en) * | 2005-08-22 | 2011-06-21 | Boston Scientific Scimed, Inc. | Local perfusion device |
| US7785289B2 (en) * | 2006-10-17 | 2010-08-31 | Boston Scientific Scimed, Inc. | Catheter with flexible, non-kinking elongate member |
| US20080125747A1 (en) * | 2006-11-28 | 2008-05-29 | Smith & Nephew, Inc.-Tn | Passive thermal spine catheter |
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| US7920928B1 (en) * | 2007-01-31 | 2011-04-05 | Pacesetter, Inc. | Passive fixation for epicardial lead |
| WO2012012807A2 (en) * | 2010-07-23 | 2012-01-26 | Board Of Regents Of The University Of Texas Systems | Surgical cooling device |
| EP2736581A4 (en) | 2011-07-25 | 2015-11-04 | Neurosave Inc | Non-invasive systems, devices, and methods for selective brain cooling |
| DE102011057009B4 (en) * | 2011-12-23 | 2019-02-21 | Adceris Gmbh & Co. Kg | Medical device for endovascular cooling and / or heating of blood |
| DE102012101524B4 (en) * | 2012-02-24 | 2013-12-12 | Acandis Gmbh & Co. Kg | Medical heat exchanger for endovascular tempering of blood and arrangement with such a heat exchanger |
| IL219477A0 (en) | 2012-04-30 | 2012-07-31 | Berger Thermal Res Ltd | A method for coupling between catheter tip and tissue by icing their interface and apparatus therefor |
| DE102012111581B4 (en) * | 2012-11-29 | 2018-05-09 | Acandis Gmbh & Co. Kg | Medical tempering for endovascular tempering of blood and system with such a tempering |
| WO2014102754A1 (en) * | 2012-12-31 | 2014-07-03 | Krishnan Subramaniam C | Catheter for vascular imaging, method of imaging, and method for interventional procedure using the catheter |
| JP7085762B2 (en) | 2017-04-05 | 2022-06-17 | ミラキ イノベーション シンク タンク エルエルシー | Cold slurry confinement |
| US20200054341A1 (en) * | 2018-08-14 | 2020-02-20 | Csa Medical, Inc. | Devices and methods for isolating a treatment region in the body from other regions |
| KR102316569B1 (en) * | 2019-10-10 | 2021-10-21 | 한양대학교 산학협력단 | Laparoscpoic apparatus and method for preventing ischemic organ damage using the same |
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-
2003
- 2003-06-25 US US10/603,705 patent/US20040267338A1/en not_active Abandoned
-
2004
- 2004-06-23 JP JP2006517543A patent/JP4668182B2/en not_active Expired - Fee Related
- 2004-06-23 WO PCT/US2004/019992 patent/WO2005002478A2/en active Application Filing
- 2004-06-23 CA CA2530394A patent/CA2530394C/en not_active Expired - Fee Related
- 2004-06-23 EP EP04755865A patent/EP1646342A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005002478A2 (en) | 2005-01-13 |
| EP1646342A2 (en) | 2006-04-19 |
| JP2007515991A (en) | 2007-06-21 |
| CA2530394C (en) | 2012-07-31 |
| JP4668182B2 (en) | 2011-04-13 |
| WO2005002478A3 (en) | 2005-04-28 |
| US20040267338A1 (en) | 2004-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20180626 |