CA2531467A1 - Method and device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body - Google Patents

Method and device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body Download PDF

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Publication number
CA2531467A1
CA2531467A1 CA002531467A CA2531467A CA2531467A1 CA 2531467 A1 CA2531467 A1 CA 2531467A1 CA 002531467 A CA002531467 A CA 002531467A CA 2531467 A CA2531467 A CA 2531467A CA 2531467 A1 CA2531467 A1 CA 2531467A1
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CA
Canada
Prior art keywords
cndot
radiation
dose
quality index
calculating
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002531467A
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French (fr)
Inventor
Tufve Nyholm
Joergen Olofsson
Anders Ahnesjoe
Mikael Karlsson
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Nucletron Operations BV
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Nucletron Operations BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucletron Operations BV filed Critical Nucletron Operations BV
Publication of CA2531467A1 publication Critical patent/CA2531467A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A61N5/1031—Treatment planning systems using a specific method of dose optimization
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29—Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A61N5/1031—Treatment planning systems using a specific method of dose optimization
    • A61N2005/1034—Monte Carlo type methods; particle tracking

Abstract

The invention relates to a method for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body, wherein said radiation beam of the radiation treatment system exhibits a specific beam field size and shape at different depths as well as to a device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body, wherein said radiation beam of the radiation treatment system exhibits a specific beam field size and shape at different depths.
It is an object of the invention to provide a method and device according to the above allowing the calculation of a radiation dose distribution for a radiation treatment system using a limited amount of data whilst preserving the required accuracy.
According to the invention the method is characterized by the steps of i) determining at least one beam quality index being representative for said radiation beam being used, and ii) calculating said radiation dose distribution in said specific beam field using parameterized dose deposition kernels based on said at least one beam quality index.

Claims (12)

1. Method for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body, wherein said radiation beam of the radiation treatment system exhibits a specific beam field size and shape at different depths, wherein the method is characterized by the steps of:
i) determining at least one beam quality index being representative for said radiation beam being used, and ii) calculating said radiation dose distribution in said specific beam field using parameterized dose deposition kernels based on said at least one beam quality index.
2. Method according to claim 1, further characterized by the steps of iii) using for different devices pre-collected measured radiation beam data, said measured radiation beam data comprising:
a) measured phantom dose data at different depths, for different field shapes and sizes and at different energies;
b) calculated dose deposition kernel parameters;
c) measured head scatter factors and output factors that can be transformed into phantom scatter factors for the corresponding field sizes, iv) determining said at least one beam quality index according to step i) using the pre-collected measured radiation beam data according to step iii);
v) associating the dose deposition kernel parameters to said one or a few beam quality index being determined.
3. Method according to claim 1, further characterized by step vi) using Monte Carlo simulations to simulate said measured data according to step iii).
4. Method according to any one of the preceding claims, further characterized in that said at least one beam quality index is determined by the ratio between the tissue phantom ratio (TPR) measured at d1=20 cm and d2=10 cm depth (TPR20,10).
5. Method according to any one of the preceding claims, further characterized in that said at least one beam quality index is determined by the percentage depth dose (PDD) at d3=10 cm (PDD10).
6. Method according to any one of the claims 2-5, further characterized in that the dose deposition kernels are pencil dose deposition kernels.
7. Method according to any one of the claims 2-5, further characterized in that the dose deposition kernels are point dose deposition kernels.
8. Method according to any one of the preceding claims, characterized in that the dose per energy fluence at the central axis of the radiation beam is determined as:
wherein the parameters are defined as:
and .alpha. = .alpha.1 + .alpha.2z (7e) and where
9. Method according to claim 8, characterized in that the parameters are expressed through µ, which is a function of TPR(d2,d1) (TPR20,10) with the following expressions:
µ = -0.363009.cndot.TPR20,10 3 + 0.709250.cndot.TPR20,10 2 -0.259794.cndot.TPR20,10 - 0.090314 A1 = -0.0042.cndot.µ3 - 0.46571.cndot.µ2 - 0.099992.cndot.µ +
0.0002918 A2 = -1605.6.cndot.µ2 - 64.40.cndot.µ - 1.239 A3 = -0.016.cndot.µ4 - 0.0055.cndot.µ3 - 0.01246.cndot.µ2 +
0.991726.cndot.µ + 0.0002103 A4 = 0.007.cndot.µ3 - 0.1081.cndot.µ2 - 0.01211.cndot.µ - 0.000208 A5 = 0.003.cndot.µ2 + 0.805.cndot.µ + 0.23061 a1 = -2852.cndot.µ3 + 1641.cndot.µ2 + 47.00.cndot.µ + 2.007 a2 = -0.010.cndot.µ - 0.016 B1 = -69680.47.cndot.µ4 - 12517.918.cndot.µ3 - 780.2216.cndot.µ2 -20.948788.cndot.µ - 0.20531052 B2 = -16.675.cndot.µ2 - 2.0546.cndot.µ - 0.06840 B3 = 1.0011.cndot.µ + 8.1.cndot.10 -5 B4 = 0.0033.cndot.µ3 - 0.11080.cndot.µ2 - 0.012183.cndot.µ -0,0002067 B5 = 2290.cndot.µ2 + 225.17.cndot.µ + 7.084 b1 = 5415900.cndot.µ5 +1573050.cndot.µ4 + 180100,6.cndot.µ3 +
10207,44.cndot.µ2 + 285,8012.cndot.µ+3,35788 b2 = -267,83.cndot.µ2 - 26.215.cndot.µ - 0.93285 b3 = 462400.cndot.µ5 + 87700.cndot.µ4 + 5070.5.cndot.µ3 +
9.641.cndot.µ2 - 6.3843.cndot.µ - 0,15488 b4 = -12319.cndot.µ5 - 2953.1.cndot.µ4 - 263.64.cndot.µ3 -
10.2445.cndot.µ - 0.158854.cndot.µ - 0.0003494 and b5 = 14.15.cndot.µ + 1.17168.

10. Device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body, wherein said radiation beam of the radiation treatment system exhibits a specific beam field size and shape at different depths, characterized in that the device further comprising inputting means arranged for inputting at least one beam quality index being representative for said radiation beam being used to calculating means, said calculating means being arranged for calculating said radiation dose distribution using parameterized dose deposition kernels being based on said at least one beam quality index.
11. Device according to claim 10, characterized in that the device is a monitor unit (MU) checking device.
12. Device according to claim 10, characterized in that the device is a IMRT treatment MU checking device.
CA002531467A 2004-12-23 2005-12-22 Method and device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body Abandoned CA2531467A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04078493A EP1674129B1 (en) 2004-12-23 2004-12-23 Method and device for calculating the radiation dose distribution for a radiation treatment system for the purpose of radiation therapy of an animal body
EP04078493.6 2004-12-23

Publications (1)

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CA2531467A1 true CA2531467A1 (en) 2006-06-23

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US (1) US7542545B2 (en)
EP (1) EP1674129B1 (en)
JP (1) JP4936723B2 (en)
AT (1) ATE441460T1 (en)
AU (1) AU2005239691A1 (en)
CA (1) CA2531467A1 (en)
DE (1) DE602004022964D1 (en)
DK (1) DK1674129T3 (en)
ES (1) ES2330936T3 (en)
PL (1) PL1674129T3 (en)
PT (1) PT1674129E (en)

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ES2330936T3 (en) 2009-12-17
DE602004022964D1 (en) 2009-10-15
JP4936723B2 (en) 2012-05-23
AU2005239691A1 (en) 2006-07-13
PT1674129E (en) 2009-11-17
JP2006175239A (en) 2006-07-06
PL1674129T3 (en) 2010-02-26
EP1674129A1 (en) 2006-06-28
US7542545B2 (en) 2009-06-02
ATE441460T1 (en) 2009-09-15
US20060203964A1 (en) 2006-09-14
DK1674129T3 (en) 2009-11-23
EP1674129B1 (en) 2009-09-02

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Effective date: 20131224