CA2585691A1 - Enhanced bimatoprost ophthalmic solution - Google Patents

Enhanced bimatoprost ophthalmic solution Download PDF

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Publication number
CA2585691A1
CA2585691A1 CA002585691A CA2585691A CA2585691A1 CA 2585691 A1 CA2585691 A1 CA 2585691A1 CA 002585691 A CA002585691 A CA 002585691A CA 2585691 A CA2585691 A CA 2585691A CA 2585691 A1 CA2585691 A1 CA 2585691A1
Authority
CA
Canada
Prior art keywords
ophthalmic solution
bimatoprost ophthalmic
enhanced
enhanced bimatoprost
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002585691A
Other languages
French (fr)
Other versions
CA2585691C (en
Inventor
Chin-Ming Chang
James N. Chang
Rhett M. Schiffman
R. Scott Jordan
Joan-En Chang-Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan, Inc.
Chin-Ming Chang
James N. Chang
Rhett M. Schiffman
R. Scott Jordan
Joan-En Chang-Lin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36613401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2585691(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan, Inc., Chin-Ming Chang, James N. Chang, Rhett M. Schiffman, R. Scott Jordan, Joan-En Chang-Lin filed Critical Allergan, Inc.
Publication of CA2585691A1 publication Critical patent/CA2585691A1/en
Application granted granted Critical
Publication of CA2585691C publication Critical patent/CA2585691C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/12Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics

Abstract

A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
CA002585691A 2005-03-16 2006-03-14 Enhanced bimatoprost ophthalmic solution Active CA2585691C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/083,261 US7851504B2 (en) 2005-03-16 2005-03-16 Enhanced bimatoprost ophthalmic solution
US11/083,261 2005-03-16
PCT/US2006/009124 WO2006101839A2 (en) 2005-03-16 2006-03-14 Enhanced bimatoprost ophthalmic solution

Publications (2)

Publication Number Publication Date
CA2585691A1 true CA2585691A1 (en) 2006-09-28
CA2585691C CA2585691C (en) 2009-05-19

Family

ID=36613401

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002585691A Active CA2585691C (en) 2005-03-16 2006-03-14 Enhanced bimatoprost ophthalmic solution

Country Status (23)

Country Link
US (10) US7851504B2 (en)
EP (1) EP1753434B2 (en)
JP (3) JP5367946B2 (en)
KR (2) KR20120068051A (en)
CN (2) CN101137383B (en)
AR (1) AR055050A1 (en)
AT (1) ATE431152T1 (en)
AU (1) AU2006227757B2 (en)
BR (1) BRPI0607447B1 (en)
CA (1) CA2585691C (en)
DE (1) DE602006006762D1 (en)
DK (1) DK1753434T4 (en)
ES (1) ES2324058T5 (en)
HK (1) HK1104211A1 (en)
IL (1) IL185744A (en)
MX (1) MX2007011300A (en)
NO (1) NO337190B1 (en)
NZ (1) NZ560788A (en)
PL (1) PL1753434T5 (en)
RU (1) RU2363471C2 (en)
TW (1) TWI399207B (en)
WO (1) WO2006101839A2 (en)
ZA (1) ZA200707246B (en)

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US20160250225A1 (en) 2016-09-01
PL1753434T5 (en) 2018-05-30
NO20074390L (en) 2007-10-15
ES2324058T5 (en) 2018-05-22
BRPI0607447A2 (en) 2009-09-01
RU2363471C2 (en) 2009-08-10
ATE431152T1 (en) 2009-05-15
BRPI0607447B1 (en) 2022-09-27
DK1753434T4 (en) 2018-03-05
MX2007011300A (en) 2007-10-05
AR055050A1 (en) 2007-08-01
AU2006227757B2 (en) 2011-07-14
US20060211770A1 (en) 2006-09-21
KR20120068051A (en) 2012-06-26
NO337190B1 (en) 2016-02-08
EP1753434B1 (en) 2009-05-13
CN101137383A (en) 2008-03-05
CN101137383B (en) 2011-06-15
JP5563515B2 (en) 2014-07-30
JP2008511539A (en) 2008-04-17
US7851504B2 (en) 2010-12-14
IL185744A (en) 2015-09-24
DK1753434T3 (en) 2009-08-03
EP1753434A2 (en) 2007-02-21
US8933120B2 (en) 2015-01-13
US20130102678A1 (en) 2013-04-25
US20140100287A1 (en) 2014-04-10
IL185744A0 (en) 2008-01-06
US20120142782A1 (en) 2012-06-07
US20120142783A1 (en) 2012-06-07
JP5367946B2 (en) 2013-12-11
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