CA2587394A1 - Cooling devices with flexible sensors - Google Patents

Cooling devices with flexible sensors Download PDF

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Publication number
CA2587394A1
CA2587394A1 CA002587394A CA2587394A CA2587394A1 CA 2587394 A1 CA2587394 A1 CA 2587394A1 CA 002587394 A CA002587394 A CA 002587394A CA 2587394 A CA2587394 A CA 2587394A CA 2587394 A1 CA2587394 A1 CA 2587394A1
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CA
Canada
Prior art keywords
sensing device
skin
subject
temperature sensor
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002587394A
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French (fr)
Other versions
CA2587394C (en
Inventor
Mitchell Levinson
Jesse Nicasio Rosen
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Zeltiq Aesthetics Inc
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Zeltiq Aesthetics Inc
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Publication of CA2587394A1 publication Critical patent/CA2587394A1/en
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Publication of CA2587394C publication Critical patent/CA2587394C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10—Cooling bags, e.g. ice-bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843—Monitoring or controlling sensor contact pressure
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/19—Control of temperature characterised by the use of electric means
    • G05D23/1919—Control of temperature characterised by the use of electric means characterised by the type of controller
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/19—Control of temperature characterised by the use of electric means
    • G05D23/20—Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature
    • G05D23/22—Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element being a thermocouple
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/19—Control of temperature characterised by the use of electric means
    • G05D23/20—Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature
    • G05D23/24—Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element having a resistance varying with temperature, e.g. a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature
    • A61B2017/00088—Temperature using thermistors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature
    • A61B2017/00092—Temperature using thermocouples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature
    • A61B2017/00101—Temperature using an array of thermosensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00047—Cooling or heating of the probe or tissue immediately surrounding the probe using Peltier effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00744—Fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/164—Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted in or on a conformable substrate or carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
    • A61F2007/0228—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof with belt or strap, e.g. with buckle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A61F2007/029—Fat cell removal or destruction by non-ablative heat treatment

Abstract

A device for exchanging heat with a subject having skin is provided. The device includes a heat exchanging member having a heat transfer surface configured to form a heat conducting interface with the subject's skin. The device further includes a substantially flexible sensing device disposed in the interface between the heat exchanging member and the subject's skin. The sensing device is configured to measure a parameter of the interface without substantially impeding heat transfer between the heat exchanging member and the subject's skin.

Claims (30)

1. ~A device for removing heat from subcutaneous lipid-rich cells of a subject having skin, comprising:
a heat exchanging member having a heat transfer surface configured to form a heat conducting interface with the subject's skin to remove heat from the lipid-rich cells such that the lipid-rich cells are substantially affected while non-lipid-rich cells in the epidermis are not substantially affected;
and a substantially flexible sensing device disposed in the interface between the heat exchanging member and the subject's skin, wherein the sensing device is configured to sense a parameter at the interface.
2. ~The device of claim 1 wherein the sensing device is further configured to sense a parameter at the interface without substantially impeding heat transfer between the heat exchanging member and the subject's skin.
3. ~The device of claim 1, further comprising a thermally conductive sleeve configured to be releasably retained on the heat exchanging member, wherein the sensing element is incorporated into the sleeve.
4. ~The device of claim 1, wherein the sensing device is a temperature sensor.
5. ~The device of claim 1, wherein the sensing device includes a substrate and a temperature sensor disposed on the substrate.
6. The device of claim 5, wherein the temperature sensor includes first and second metal traces deposited on the substrate, the first and second metal traces at least partially contacting each other to form a bi-metal junction.
7. The device of claim 1, wherein the sensing device includes a first surface corresponding to the heat transfer surface and a second surface opposite the first surface and corresponding to the subject's skin, and wherein a first sensor is disposed on the first surface and a second sensor is disposed on the second surface.
8. The device of claim 1, wherein the sensing device includes a pressure sensor and a temperature sensor.
9. The device of claim 1, further comprising a measuring circuit in electrical communication with the sensing device and configured to convert electrical temperature signals from the sensing device to temperatures in degrees Celsius or Fahrenheit.
10. The device of claim 9, further comprising a logic controller in electrical communication with the measuring circuit and configured to control a temperature of the subject's skin and/or the heat exchanging member based on the interface temperature measured by the sensing device.
11. The device of claim 1, further comprising a plurality of sensing devices configured to provide temperature information about the interface at regions on the heat exchanging member.
12. A sensing device for measuring parameters of a heat transfer interface between a subject having skin and a cooling device, comprising:
a substantially flexible substrate positioned in the heat transfer interface between the subject's skin and the cooling device, the substrate having a surface facing the cooling device; and a sensor disposed on the surface of the substrate, the sensor configured to measure a temperature of the heat transfer interface without substantially impeding heat transfer between the cooling device and the subject's skin.
13. The sensing device of claim 12 wherein with heat transfer interface is configured to remove heat from the lipid-rich cells of the subject's skin such that the lipid-rich cells are substantially affected while non-lipid-rich cells in the epidermis are not substantially affected.
14. The sensing device of claim 12 wherein the sensor is a temperature sensor.
15. The sensing device of claim 14, wherein the temperature sensor includes a thermocouple type selected from the group consisting of the types J, K, T, E, N, R, S, U, and B.
16. The sensing device of claim 15, wherein the temperature sensor includes a first metal portion and a second metal portion spaced apart from the first metal portion, the first and second metal portions forming a bi-metal junction.
17. The sensing device of claim 15, wherein the temperature sensor includes two metal films sputtered, etched, or printed onto the substrate.
18. The sensing device of claim 14, wherein the temperature sensor is a first temperature sensor and the surface is a first surface, and wherein the substrate further includes a second surface opposite the first surface, and the device further includes a second temperature sensor disposed on the second surface.
19. The sensing device of claim 14, further comprising a pressure sensor disposed on the surface.
20. The sensing device of claim 14, wherein the temperature sensor includes one of a thermistor, a Resistive Temperature Detector or a thermopile deposited onto the substrate.
21. The sensing device of claim 20, wherein the temperature sensor is a metal foil type Resistive Temperature Detector.
22. The sensing device of claim 14, further comprising a measuring circuit in electrical communication with the temperature sensor and configured to convert electrical signals from the temperature sensor to temperatures in degrees Celsius or Fahrenheit.
23. A method of applying a cooling device configured for removing heat from a subject having skin, comprising:
disposing a sensing device proximate to the cooling device, the sensing device being substantially flexible and at least partially conforming to the cooling device;
positioning the cooling device and the sensing device proximate to the subject's skin, wherein the cooling device and the subject's skin form a heat transfer interface, in which the sensing device is positioned;
measuring a parameter of the heat transfer interface using the sensing device;

and removing heat from a region of the subject's skin under the epidermis such that lipid-rich cells are substantially affected while non-lipid-rich cells in the epidermis are not substantially affected.
24. The method of claim 23, wherein the lipid-rich cells are adipocytes.
25. The method of claim 23, further comprising controlling a rate of heat removal from the subject's skin to the cooling device based on a measured parameter of the heat transfer interface.
26. The method of claim 23, further comprising maintaining a temperature of the heat transfer interface based on a measured temperature of the heat transfer interface.
27. The method of claim 23, further comprising, indicating a temperature alarm if a measured temperature of the heat transfer interface is outside a specified target range.
28. The method of claim 23, wherein the sensing device includes a substrate having a first surface facing the cooling device and a second surface opposite the first surface, and wherein the sensing device further includes a first temperature sensor disposed on the first surface and a second temperature sensor disposed on the second surface, the method further comprising:
measuring a temperature of the cooling device using the first temperature sensor; and measuring a temperature of the subject's skin using the second temperature sensor.
29. The method of claim 23, wherein the sensing device further includes a pressure sensor, the method further comprising:
pressing the cooling device and the sensing device against the subject's skin;

measuring a pressure between the cooling device and the subject's skin using the pressure sensor; and if the measured pressure is not less than a pressure threshold, indicating sufficient contact between the cooling device and the subject's skin;
and if the measured pressure is less than the pressure threshold, indicating insufficient contact between the cooling device and the subject's skin.
30. The method of claim 23, wherein the sensing device is incorporated into a sleeve, the method further comprising isolating the cooling device from the subject's skin using the sleeve.
CA2587394A 2006-09-26 2007-03-14 Cooling devices with flexible sensors Active CA2587394C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/528,189 US20080077201A1 (en) 2006-09-26 2006-09-26 Cooling devices with flexible sensors
US11/528,189 2006-09-26
PCT/US2007/064017 WO2008039556A1 (en) 2006-09-26 2007-03-14 Cooling devices with flexible sensors

Publications (2)

Publication Number Publication Date
CA2587394A1 true CA2587394A1 (en) 2008-03-26
CA2587394C CA2587394C (en) 2010-05-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2587394A Active CA2587394C (en) 2006-09-26 2007-03-14 Cooling devices with flexible sensors

Country Status (8)

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US (2) US20080077201A1 (en)
EP (1) EP2077784B1 (en)
JP (2) JP4733189B2 (en)
AU (1) AU2007202441A1 (en)
CA (1) CA2587394C (en)
ES (1) ES2764776T3 (en)
IL (1) IL182050A0 (en)
WO (1) WO2008039556A1 (en)

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