CA2589922A1 - Respiratory devices and methods of use - Google Patents

Respiratory devices and methods of use Download PDF

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Publication number
CA2589922A1
CA2589922A1 CA002589922A CA2589922A CA2589922A1 CA 2589922 A1 CA2589922 A1 CA 2589922A1 CA 002589922 A CA002589922 A CA 002589922A CA 2589922 A CA2589922 A CA 2589922A CA 2589922 A1 CA2589922 A1 CA 2589922A1
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CA
Canada
Prior art keywords
respiratory device
nasal cavity
respiratory
passageway
holdfast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002589922A
Other languages
French (fr)
Inventor
Rajiv Doshi
Robert A. Howard
Motohide Hatanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventus Medical Inc
Original Assignee
Ventus Medical, Inc.
Rajiv Doshi
Robert A. Howard
Motohide Hatanaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventus Medical, Inc., Rajiv Doshi, Robert A. Howard, Motohide Hatanaka filed Critical Ventus Medical, Inc.
Publication of CA2589922A1 publication Critical patent/CA2589922A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/01—Orthopaedic devices, e.g. splints, casts or braces
    • A61F5/08—Devices for correcting deformities of the nose ; Devices for enlarging the nostril, e.g. for breathing improvement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/56—Devices for preventing snoring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/56—Devices for preventing snoring
    • A61F5/566—Intra-oral devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A61M15/085—Fixing means therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0683—Holding devices therefor
    • A61M16/0688—Holding devices therefor by means of an adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0605—Means for improving the adaptation of the mask to the patient
    • A61M16/0616—Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0683—Holding devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0683—Holding devices therefor
    • A61M16/0694—Chin straps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/1065—Filters in a path in the expiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/208—Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62B—DEVICES, APPARATUS OR METHODS FOR LIFE-SAVING
    • A62B23/00—Filters for breathing-protection purposes
    • A62B23/06—Nose filters

Abstract

Described here are methods, devices, and kits for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from "pursed-lip" breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

Claims (94)

1. A respiratory device adapted to be removably secured in communication with a nasal cavity comprising:

a passageway;

an airflow resistor in communication with the passageway; and a holdfast for removably securing the respiratory device in communication with the nasal cavity.
2. The respiratory device of claim 1 further comprising a rim for supporting the passageway.
3. The respiratory device of claim 1 wherein the airflow resistor increases the resistance to air exhaled and/or inhaled through the passageway.
4. The respiratory device of claim 3 wherein the airflow resistor increases the resistance to air exhaled through the passageway but does not substantially increase the resistance to air inhaled through the passageway.
5. The respiratory device of claim 3 wherein the airflow resistor increases the resistance to air exhaled through the passageway more than it increases the resistance to air inhaled through the passageway.
6. The respiratory device of claim 3 wherein the airflow resistor decreases the resistance to air exhaled and/or inhaled through the passageway when the airflow or air pressure differential across the airflow resistor exceeds a threshold level.
7. The respiratory device of claim 3 wherein the airflow resistor increases the resistance to air exhaled and/or inhaled through the passageway when the airflow or the air pressure differential across the airflow resistor falls below a threshold level.
8. The respiratory device of claim 1 wherein the airflow resistor is a nested airflow resistor.
9. The respiratory device of claim 1 wherein the airflow resistor is a flap valve.
10. The respiratory device of claim 1 wherein the airflow resistor alters the inspiratory:expiratory ratio of a user wearing the respiratory device so that the inspiratory:expiratory ratio is between about 3:1 and about 1:10.
11. The respiratory device of claim 1 wherein the airflow resistor alters the inspiratory:expiratory ratio of a user wearing the respiratory device so that the inspiratory:expiratory ratio is between about 1:1.5 and about 1:4.
12. The respiratory device of claim 1 wherein the airflow resistor alters the inspiratory:expiratory ratio of a user wearing the respiratory device to about 1:3.
13. The respiratory device of claim 1 wherein the holdfast removably secures the respiratory device in communication with a nasal cavity of a user so that at least some of the air exchanged between the nasal cavity and the external environment of a user passes through the respiratory device.
14. The respiratory device of claim 13 wherein the holdfast removably secures the respiratory device in communication with a nasal cavity of a user so that all of the air exchanged between the nasal cavity and the external environment of a user passes through the respiratory device.
15. The respiratory device of claim 13 wherein the holdfast removably secures the respiratory device at least partly within the nasal cavity of a user.
16. The respiratory device of claim 15 wherein an outer region of the respiratory device exerts pressure against the nasal cavity of a user.
17. The respiratory device of claim 1 wherein the holdfast removably secures the respiratory device in communication with both nasal cavities.
18. The respiratory device of claim 17 wherein the holdfast removably secures the respiratory device at least partly within both nasal cavities of a user.
19. The respiratory device of claim 1 wherein the holdfast removably secures the respiratory device in communication with an oral and a nasal cavity of a user.
20. The respiratory device of claim 1 further comprising an active agent.
21. The respiratory device of claim 20 wherein the active agent comprises a drug.
22 The respiratory device of claim 20 wherein the active agent comprises an odorant.
23. The respiratory device of claim 20 wherein the active agent comprises menthol.
24. The respiratory device of claim 1 further comprising a filter.
25. The respiratory device of claim 24 wherein the filter comprises a movable filter.
26. The respiratory device of claim 1 wherein the holdfast comprises a conformable material.
27. The respiratory device of claim 1 further comprising a respiratory gas supply.
28. A respiratory device adapted to be removably secured in a nasal cavity comprising:

a passageway;

a rim having sufficient strength to support the passageway in the open state while inserted into the nasal cavity; and a holdfast for securing the respiratory device to at least one nasal cavity, wherein the respiratory device may be applied or removed by a user.
29. A kit comprising:

a respiratory device of claim 1; and instructions on the use of the respiratory device.
30. A respiratory device adapted to be removably secured in a nasal cavity comprising:

a passageway;

a filter within the passageway; and a holdfast for removably securing the respiratory device at least partly within a nasal cavity.
31. The respiratory device of claim 30 further comprising a rim for supporting the passageway.
32. The respiratory device of claim 30 wherein the filter comprises a movable filter for filtering air flowing through the device in a first direction more than air flowing through the device in a direction that is opposite of the first direction.
33. The respiratory device of claim 32 wherein the filter filters air inhaled through the passageway but does not substantially filter air exhaled through the passageway.
34. The respiratory device of claim 32 wherein the filter increases the resistance to air exhaled through the passageway more than it increases the resistance to air inhaled through the passageway.
35. The respiratory device of claim 30 wherein the holdfast removably secures the respiratory device in communication with a nasal cavity of a user so that at least some of the air exchanged between the nasal cavity and the external environment of a user passes through the respiratory device.
36. The respiratory device of claim 35 wherein the holdfast removably secures the respiratory device in communication with a nasal cavity of a user so that all of the air exchanged between the nasal cavity and the external environment of a user passes through the respiratory device.
37. The respiratory device of claim 35 wherein the holdfast removably secures the respiratory device at least partly within the nasal cavity of a user.
38. The respiratory device of claim 37 wherein an outer region of the respiratory device exerts pressure against the nasal cavity of a user.
39. The respiratory device of claim 30 wherein the holdfast removably secures the respiratory device in communication with both nasal cavities.
40. The respiratory device of claim 39 wherein the holdfast removably secures the respiratory device at least partly within both nasal cavities of a user.
41. The respiratory device of claim 30 wherein the holdfast removably secures the respiratory device in communication with an oral and a nasal cavity of a user.
42. The respiratory device of claim 30 further comprising an active agent.
43. The respiratory device of claim 42 wherein the active agent comprises a drug.
44. The respiratory device of claim 42 wherein the active agent comprises an odorant.
45. The respiratory device of claim 42 wherein the active agent comprises menthol.
46. The respiratory device of claim 30 wherein the holdfast comprises a conformable material.
47. The respiratory device of claim 30 further comprising a respiratory gas supply.
48. A respiratory device adapted to be removably secured in a nasal cavity comprising:

a passageway;

a filter within the passageway a rim having sufficient strength to support the passageway in the open state while inserted into the nasal cavity; and a holdfast for securing the respiratory device to at least one nasal cavity, wherein the respiratory device may be applied or removed by a user.
49. A kit comprising:

a respiratory device of claim 30; and instructions on the use of the respiratory device.
50. A respiratory device adapted to be removably secured in communication with an oral cavity comprising:

a passageway;

an airflow resistor in communication with the passageway; and a holdfast for removably securing the respiratory device substantially within a portion of the oral cavity.
51. The respiratory device of claim 50 wherein the airflow resistor increases the resistance to air exhaled and/or inhaled through the passageway.
52. The respiratory device of claim 51 wherein the airflow resistor increases the resistance to air exhaled through the passageway but does not substantially increase the resistance to air inhaled through the passageway.
53. The respiratory device of claim 51 wherein the airflow resistor increases the resistance to air exhaled through the passageway more than it increases the resistance to air inhaled through the passageway.
54. The respiratory device of claim 51 wherein the airflow resistor decreases the resistance to air exhaled and/or inhaled through the passageway when the airflow or air pressure differential across the airflow resistor exceeds a threshold level.
55. The respiratory device of claim 51 wherein the airflow resistor increases the resistance to air exhaled and/or inhaled through the passageway when the airflow or the air pressure differential across the airflow resistor falls below a threshold level.
56. The respiratory device of claim 51 wherein the airflow resistor is a nested airflow resistor.
57. The respiratory device of claim 50 wherein the airflow resistor is a flap valve.
58. The respiratory device of claim 50 wherein the airflow resistor alters the inspiratory:expiratory ratio of a user wearing the respiratory device so that the inspiratory:expiratory ratio is between about 3:1 and about 1:10.
59. The respiratory device of claim 50 wherein the airflow resistor alters the inspiratory:expiratory ratio of a user wearing the respiratory device so that the inspiratory:expiratory ratio is between about 1:1.5 and about 1:4.
60. The respiratory device of claim 50 wherein the airflow resistor is alters the inspiratory:expiratory ratio of a user wearing the respiratory device to about 1:3.
61. The respiratory device of claim 50 wherein the holdfast removably secures the respiratory device substantially within the oral cavity of a user so that at least some of the air exchanged between the oral cavity and the user's external environment passes through the respiratory device.
62. The respiratory device of claim 61 wherein the holdfast removably secures the respiratory device substantially within the oral cavity of a user so that all of the air exchanged between the oral cavity and the user's external environment passes through the respiratory device.
63. The respiratory device of claim 50 further comprising an active agent.
64. The respiratory device of claim 63 wherein the active agent comprises an odorant.
65. The respiratory device of claim 63 wherein the active agent comprises menthol.
66. The respiratory device of claim 50 further comprising a filter.
67. The respiratory device of claim 66 wherein the filter comprises a movable filter.
68. The respiratory device of claim 50 wherein the holdfast comprises a conformable material.
69. The respiratory device of claim 50 further comprising a respiratory gas supply.
70. A method of treating a respiratory disorder comprising:

removably securing a respiratory device in communication with a patient's nasal cavity, wherein the respiratory device comprises an airflow resistor that inhibits expiration more than it inhibits inhalation and a holdfast configured to removably secure the respiratory device at least partly within the nasal cavity;

allowing the patient to breathe through the respiratory device.
71. The method of claim 70, wherein the disorder treated is selected from the group consisting of: chronic obstructive pulmonary disease, sleeping disorders, gastroenterologic disorders, and cardiovascular disorders.
72. The method of claim 70, wherein the step of removably securing the respiratory device comprises inserting the respiratory device into the subject's nostril.
73. The method of claim 70, wherein the step of removably securing the respiratory device comprises inserting a respiratory device into both of the subject's nostrils.
74. The method of claim 70, further comprising compressing at least a portion of the respiratory device so that it can fit within a subject's nasal cavity.
75. The method of claim 70, wherein the step of removably securing the respiratory device in communication with a patient's nasal cavity comprises engaging a holdfast region of the respiratory device with at least a portion of the subject's nasal cavity.
76. The method of claim 70, wherein the respiratory device is removably secured at least partly within a patient's nasal cavity using an adhesive.
77. The method of claim 70, wherein the respiratory device is removably secured at least partly within a patient's nasal cavity by a friction fit.
78. The method of claim 70, further comprising removing the respiratory device from a sterile packaging before removably securing the respiratory device.
79. The method of claim 70, further comprising removing the respiratory device from clean packaging before removably securing the respiratory device.
80. A method of regulating pCO2 in a patient comprising:

inserting at least a portion of a respiratory device into a subject's nasal cavity;
removably securing the respiratory device at least partly within a patient's nasal cavity, wherein the respiratory device comprises an airflow resistor that inhibits expiration more than it inhibits inhalation, and a holdfast configured to removably secure the respiratory device at least partly within the nasal cavity;

allowing the patient to breathe through the respiratory device.
81. The method of claim 80, wherein the step of inserting the respiratory device into a subject's nasal cavity comprises inserting a respiratory device into both of the subject's nostrils.
82. The method of claim 80, further comprising compressing at least a portion of the respiratory device so that it can fit within a subject's nasal cavity.
83. The method of claim 80, wherein the step of removably securing the respiratory device in communication with a patient's nasal cavity comprises engaging the holdfast region of the respiratory device with at least a portion of the subject's nasal cavity.
84. The method of claim 83, wherein the respiratory device is removably secured at least partly within a patient's nasal cavity using an adhesive.
85 The method of claim 83, wherein the respiratory device is removably secured at least partly within a patient's nasal cavity by a friction fit.
86. The method of claim 80, further comprising removing the respiratory device from a sterile packaging before removably securing the respiratory device.
87. The method of claim 80, further comprising removing the respiratory device from clean packaging before removably securing the respiratory device.
88. A method of treating a sleep disorder comprising:

inserting at least a portion of a respiratory device into a subject's nasal cavity;
removably securing the respiratory device in communication with a patient's nasal cavity, wherein the respiratory device comprises an airflow resistor that inhibits expiration more than it inhibits inhalation.
89. The method of claim 88, wherein the sleep disorder is snoring.
90. The method of claim 88, wherein the sleep disorder is sleep apnea.
91. The method of claim 88, wherein the step of inserting at least a portion of a respiratory device into a subject's nasal cavity comprises inserting a respiratory device into each of a subject's nostrils.
92. The method of claim 88, wherein the respiratory device is removably secured at least partly within a patient's nasal cavity by a friction fit between at least a portion of the respiratory device and the subject's nostril.
93. A method of treating a respiratory disorder comprising:

removably securing a respiratory device in communication with a patient's nasal cavity, wherein the respiratory device comprises an airflow resistor that inhibits expiration more than it inhibits inhalation and a holdfast configured to removably secure the respiratory device in communication with the nasal cavity;

allowing the patient to breathe through the respiratory device.
94. The method of claim 93, wherein the disorder treated is selected from the group consisting of: chronic obstructive pulmonary disease, sleeping disorders, gastroenterologic disorders, and cardiovascular disorders.
CA002589922A 2004-12-08 2005-12-08 Respiratory devices and methods of use Abandoned CA2589922A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63471504P 2004-12-08 2004-12-08
US60/634,715 2004-12-08
PCT/US2005/044888 WO2006063339A2 (en) 2004-12-08 2005-12-08 Respiratory devices and methods of use

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CA2589922A1 true CA2589922A1 (en) 2006-06-15

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CA002589922A Abandoned CA2589922A1 (en) 2004-12-08 2005-12-08 Respiratory devices and methods of use

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US (10) US7735491B2 (en)
EP (1) EP1824544B1 (en)
JP (2) JP5230202B2 (en)
KR (1) KR20070106995A (en)
CN (2) CN101166555B (en)
AU (2) AU2005314415B2 (en)
BR (1) BRPI0518641B8 (en)
CA (1) CA2589922A1 (en)
HK (1) HK1103370A1 (en)
IL (1) IL183652A0 (en)
MX (2) MX338506B (en)
NZ (2) NZ556274A (en)
RU (1) RU2394603C2 (en)
SG (2) SG158120A1 (en)
WO (1) WO2006063339A2 (en)
ZA (2) ZA200705402B (en)

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