CA2596078A1 - End effector for surgical instrument, surgical instrument, and method for forming the end effector - Google Patents
End effector for surgical instrument, surgical instrument, and method for forming the end effector Download PDFInfo
- Publication number
- CA2596078A1 CA2596078A1 CA002596078A CA2596078A CA2596078A1 CA 2596078 A1 CA2596078 A1 CA 2596078A1 CA 002596078 A CA002596078 A CA 002596078A CA 2596078 A CA2596078 A CA 2596078A CA 2596078 A1 CA2596078 A1 CA 2596078A1
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- CA
- Canada
- Prior art keywords
- edges
- jaws
- lateral side
- end effector
- linear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/04—Endoscopic instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2901—Details of shaft
- A61B2017/2902—Details of shaft characterized by features of the actuating rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2901—Details of shaft
- A61B2017/2905—Details of shaft flexible
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B17/2909—Handles
- A61B2017/2912—Handles transmission of forces to actuating rod or piston
- A61B2017/2919—Handles transmission of forces to actuating rod or piston details of linkages or pivot points
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2926—Details of heads or jaws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2926—Details of heads or jaws
- A61B2017/2932—Transmission of forces to jaw members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B2017/320064—Surgical cutting instruments with tissue or sample retaining means
Abstract
An end effector for an endoscopic surgical instrument having a longitudinal body with proximal and distal ends and an actuator at the proximal end of the body includes a clevis to be connected to the distal end of the body and two jaws. Each of the jaws has a tang portion (240) pivotally connected to the clevis and to be connected to the actuator for pivoting the jaw. The jaw has body portion (221, 223) with a lateral side (223) having substantially straight opposing edges and a proximal portion (227) connecting the lateral side to the tang portion and a nose portion (225, 229) connected to the lateral side and having substantially linear edges at an angle to the edges of the lateral side. The hollow body and nose portions define a biopsy cup for receiving a tissue sample therein and the opposing and linear edges form a pinching surface for contacting extremities of the tissue sample.
Claims (45)
1. An end effector jaw for an endoscopic surgical instrument, comprising:
a tang portion;
a hollow body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample.
a tang portion;
a hollow body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample.
2. The jaw according to claim 1, wherein said edges of said nose portion are each connected at an angle to a respective one of said opposing edges of said lateral side.
3. The jaw according to claim 2, wherein:
said linear edges of said nose portion are two linear edges;
said opposing edges of said lateral side are two opposing edges; and said two edges of said nose portion are each connected at an angle to a respective one of said two opposing edges.
said linear edges of said nose portion are two linear edges;
said opposing edges of said lateral side are two opposing edges; and said two edges of said nose portion are each connected at an angle to a respective one of said two opposing edges.
4. The jaw according to claim 1, wherein said linear edges of said nose portion are two linear edges.
5. The jaw according to claim 4, wherein said two linear edges oppose one another.
6. The jaw according to claim 5, wherein said two linear edges oppose one another at an angle.
7. The jaw according to claim 1, wherein said nose portion forms one half of a frustoconical body having two substantially linear side edges, a substantially linear front edge, and a substantially linear front face.
8. The jaw according to claim 1, wherein said nose portion has:
a side portion connected to said lateral side and having said linear edges at said angle to said lateral side; and a front portion having:
a substantially linear front face; and a linear edge connected at an angle to each of said edges of said side portion.
a side portion connected to said lateral side and having said linear edges at said angle to said lateral side; and a front portion having:
a substantially linear front face; and a linear edge connected at an angle to each of said edges of said side portion.
9. The jaw according to claim 8, wherein said side portion and said front portion form one half of a frustoconical body.
10. The jaw according to claim 8, wherein said side portion is a set of angled side portions.
11. The jaw according to claim 10, wherein said set of angled side portions forms one half of a bi-frustoconical body.
12. The jaw according to claim 1, wherein at least one of said opposing edges and said linear edges has at least one tooth.
13. The jaw according to claim 1, wherein said opposing edges and said linear edges each has at least one tooth.
14. The jaw according to claim 1, wherein said opposing edges and said linear edges each have teeth.
15. The jaw according to claim 8, wherein said linear edge of said front portion has at least one tooth.
16. The jaw according to claim 1, wherein said tang portion, said body portion, and said nose portion are integral.
17. The jaw according to claim 16, wherein said tang portion, said body portion, and said nose portion are stamped from a single piece of material.
18. An end effector for an endoscopic surgical instrument having a longitudinal body with proximal and distal ends and an actuator at the proximal end of the body, the end effector comprising:
a clevis to be connected to the distal end of the body;
and two jaws, each of said jaws having :
a tang portion pivotally connected to said clevis and to be connected to the actuator for pivoting said jaw;
a hollow body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample.
a clevis to be connected to the distal end of the body;
and two jaws, each of said jaws having :
a tang portion pivotally connected to said clevis and to be connected to the actuator for pivoting said jaw;
a hollow body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample.
19. The end effector according to claim 18, wherein, for each of said jaws, said edges of said nose portion are each connected at an angle to a respective one of said opposing edges of said lateral side.
20. The end effector according to claim 18, wherein:
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
21. The end effector according to claim 18, wherein:
each of said opposing edges of said lateral side and said linear edges of said nose portion define an abutting periphery for each of said jaws;
a junction of said opposing edges of said lateral side and said linear edges of said side portion at said abutting periphery of each of said jaws defines a first intersection; and said abutting periphery has:
areas containing teeth; and tooth-free areas at said first intersection.
each of said opposing edges of said lateral side and said linear edges of said nose portion define an abutting periphery for each of said jaws;
a junction of said opposing edges of said lateral side and said linear edges of said side portion at said abutting periphery of each of said jaws defines a first intersection; and said abutting periphery has:
areas containing teeth; and tooth-free areas at said first intersection.
22. The end effector according to claim 21, wherein:
said nose portion has:
a front face with a front edge; and a proximal portion having said linear edges; and a junction of said front edge and said linear edges at said abutting periphery of each of said jaws defines a second intersection; and said abutting periphery contains tooth-free areas at said first and second intersections.
said nose portion has:
a front face with a front edge; and a proximal portion having said linear edges; and a junction of said front edge and said linear edges at said abutting periphery of each of said jaws defines a second intersection; and said abutting periphery contains tooth-free areas at said first and second intersections.
23. The end effector according to claim 22, wherein:
said front face is substantially planar; and said front edge is substantially linear and has at least one tooth.
said front face is substantially planar; and said front edge is substantially linear and has at least one tooth.
24. The end effector according to claim 22, wherein said end effector is to be inserted into a working channel of an endoscope and contact between said end effector and said working channel is to occur substantially at said first and second intersections.
25. An endoscopic surgical instrument, comprising:
a hollow body having a distal end and a proximal end;
the end effector according to claim 18;
said clevis connected to said distal end of said body to attach said end effector to said distal end of said hollow body; and an actuator disposed at said proximal end of said hollow body and connected through said hollow body to said tang portion of at least one of said jaws to pivot at least one of said jaws relative to the other of said jaws when actuated.
a hollow body having a distal end and a proximal end;
the end effector according to claim 18;
said clevis connected to said distal end of said body to attach said end effector to said distal end of said hollow body; and an actuator disposed at said proximal end of said hollow body and connected through said hollow body to said tang portion of at least one of said jaws to pivot at least one of said jaws relative to the other of said jaws when actuated.
26. The instrument according to claim 25, wherein said actuator pivots said at least one jaw to engage said opposing edges of said lateral side and said linear edges of said nose portion of one of said jaws with said opposing edges and said linear edges of the other of said jaws when actuated.
27. The instrument according to claim 25, wherein:
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
28. An endoscopic surgical instrument, comprising:
a hollow body having a distal end and a proximal end;
an end effector having:
a clevis connected to said distal end of said body; and two jaws, each of said jaws having:
a tang portion pivotally connected to said clevis;
a hollow body portion having:
a lateral side with substantially linear opposing edges;
and a proximate portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample; and an actuator disposed at said proximal end of said body and connected through said body to said tang portion of said jaws to pivot at least one of said jaws relative to the other of said jaws when actuated.
a hollow body having a distal end and a proximal end;
an end effector having:
a clevis connected to said distal end of said body; and two jaws, each of said jaws having:
a tang portion pivotally connected to said clevis;
a hollow body portion having:
a lateral side with substantially linear opposing edges;
and a proximate portion connecting said lateral side to said tang portion; and a hollow nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges forming a pinching surface for contacting extremities of the tissue sample; and an actuator disposed at said proximal end of said body and connected through said body to said tang portion of said jaws to pivot at least one of said jaws relative to the other of said jaws when actuated.
29. The instrument according to claim 28, wherein, for each of said jaws, said edges of said nose portion are each connected at an angle to a respective one of said opposing edges of said lateral side.
30. The instrument according to claim 28, wherein:
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
said jaws have a closed orientation; and said nose portion of each of said jaws forms one half of a frustoconical body that is fully formed by both of said jaws when said jaws are in said closed orientation.
31. The instrument according to claim 28, wherein:
each of said opposing edges of said lateral side and said linear edges of said nose portion define an abutting periphery for each jaw;
a junction of said opposing edges of said lateral side and said linear edges of said side portion at said abutting periphery of each of said jaws defines a first intersection; and said abutting periphery has:
areas containing teeth, and tooth-free areas at said first intersection.
each of said opposing edges of said lateral side and said linear edges of said nose portion define an abutting periphery for each jaw;
a junction of said opposing edges of said lateral side and said linear edges of said side portion at said abutting periphery of each of said jaws defines a first intersection; and said abutting periphery has:
areas containing teeth, and tooth-free areas at said first intersection.
32. The instrument according to claim 28, wherein:
said nose portion has:
a front face with a front edge; and a proximal portion having said linear edges; and a junction of said front edge and said linear edges at said abutting periphery of each of said jaws defines a second intersection; and said abutting periphery contains tooth-free areas at said first and second intersections.
said nose portion has:
a front face with a front edge; and a proximal portion having said linear edges; and a junction of said front edge and said linear edges at said abutting periphery of each of said jaws defines a second intersection; and said abutting periphery contains tooth-free areas at said first and second intersections.
33. The instrument according to claim 32, wherein:
said front face is substantially planar; and said front edge is substantially linear and has at least one tooth.
said front face is substantially planar; and said front edge is substantially linear and has at least one tooth.
34. The instrument according to claim 32, wherein said end effector is to be inserted into a working channel of an endoscope and contact between said end effector and said working channel is to occur substantially at said first and second intersections.
35. An end effector jaw for an endoscopic surgical instrument, comprising:
a hollow body portion having a proximal tang and a distal body with lateral sides; and a hollow nose portion connected to said body portion and having substantially linear edges at an angle to said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein and forming a pinching surface for contacting extremities of the tissue sample.
a hollow body portion having a proximal tang and a distal body with lateral sides; and a hollow nose portion connected to said body portion and having substantially linear edges at an angle to said lateral side, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein and forming a pinching surface for contacting extremities of the tissue sample.
36. The jaw according to claim 35, wherein said nose portion has:
a proximal portion connected to said body portion and having said substantially linear edges at an angle to said lateral side; and a front portion having a substantially linear front face with a substantially linear edge connected to said linear edges of said proximal portion.
a proximal portion connected to said body portion and having said substantially linear edges at an angle to said lateral side; and a front portion having a substantially linear front face with a substantially linear edge connected to said linear edges of said proximal portion.
37. An end effector jaw for an endoscopic surgical instrument, comprising:
a body portion having a proximal tang and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body.
a body portion having a proximal tang and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body.
38. An end effector for an endoscopic surgical instrument having a longitudinal body with proximal and distal ends and an actuator at the proximal end of the body, the end effector comprising:
a clevis to be connected to the distal end of the body;
and two jaws, at least one of said two jaws being pivotally connected to said clevis, each of said jaws having:
a body portion having:
a proximal tang; and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body.
a clevis to be connected to the distal end of the body;
and two jaws, at least one of said two jaws being pivotally connected to said clevis, each of said jaws having:
a body portion having:
a proximal tang; and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body.
39. The end effector according to claim 38, wherein said half-frustoconical nose portion has:
two substantially linear edges; and a substantially linear front face having a substantially linear edge connected at an angle to said two linear edges.
two substantially linear edges; and a substantially linear front face having a substantially linear edge connected at an angle to said two linear edges.
40. An end effector jaw assembly for a clevis of an endoscopic surgical instrument, comprising:
two opposing jaws to be connected to the clevis, said jaws having a closed orientation, each of said jaws having:
a body portion having:
a proximal tang; and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body and having at least two substantially linear edge segments.
two opposing jaws to be connected to the clevis, said jaws having a closed orientation, each of said jaws having:
a body portion having:
a proximal tang; and a distal body with lateral sides; and a half-frustoconical nose portion connected to said distal body and having at least two substantially linear edge segments.
41. The assembly according to claim 40, wherein:
said jaws define a central longitudinal axis; and each of said at least two edge segments has at least one tooth at least partially curved about said longitudinal axis.
said jaws define a central longitudinal axis; and each of said at least two edge segments has at least one tooth at least partially curved about said longitudinal axis.
42. The assembly according to claim 40, wherein:
said at least two substantially linear edge segments of different ones of said jaws are appositioned; and said at least one tooth of each of said jaws is interdigitated when said two jaws are in said closed orientation.
said at least two substantially linear edge segments of different ones of said jaws are appositioned; and said at least one tooth of each of said jaws is interdigitated when said two jaws are in said closed orientation.
43. An end effector jaw for an endoscopic surgical instrument, comprising:
a tang portion;
a hollow body portion having:
a lateral side with substantially linear opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion having:
a side portion a hollow nose portion connected to said lateral side and having substantially linear edges connected at an angle to said opposing edges of said lateral side; and a front portion having a substantially linear front face with a substantially linear edge connected at an angle to said linear edges of said side portion, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges of said side and front portions forming a pinching surface for contacting extremities of the tissue sample.
a tang portion;
a hollow body portion having:
a lateral side with substantially linear opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a hollow nose portion having:
a side portion a hollow nose portion connected to said lateral side and having substantially linear edges connected at an angle to said opposing edges of said lateral side; and a front portion having a substantially linear front face with a substantially linear edge connected at an angle to said linear edges of said side portion, said hollow body portion and said hollow nose portion defining a biopsy cup for receiving a tissue sample therein, said opposing edges and said linear edges of said side and front portions forming a pinching surface for contacting extremities of the tissue sample.
44. An end effector jaw for an endoscopic surgical instrument, comprising:
a tang portion;
a body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side.
a tang portion;
a body portion having:
a lateral side with substantially straight opposing edges;
and a proximal portion connecting said lateral side to said tang portion; and a nose portion connected to said lateral side and having substantially linear edges at an angle to said edges of said lateral side.
45. An end effector jaw for an endoscopic surgical instrument, comprising:
a body portion having a proximal tang and a distal body with lateral sides; and a nose portion connected to said body portion and having substantially linear edges at an angle to said lateral side.
a body portion having a proximal tang and a distal body with lateral sides; and a nose portion connected to said body portion and having substantially linear edges at an angle to said lateral side.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64853805P | 2005-01-31 | 2005-01-31 | |
US60/648,538 | 2005-01-31 | ||
US73827905P | 2005-11-18 | 2005-11-18 | |
US60/738,279 | 2005-11-18 | ||
US11/343,294 US20060184198A1 (en) | 2005-01-31 | 2006-01-30 | End effector for surgical instrument, surgical instrument, and method for forming the end effector |
US11/343,294 | 2006-01-30 | ||
PCT/US2006/003029 WO2006083728A2 (en) | 2005-01-31 | 2006-01-31 | End effector for surgical instrument, surgical instrument, and method for forming the end effector |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2596078A1 true CA2596078A1 (en) | 2006-08-10 |
CA2596078C CA2596078C (en) | 2011-09-06 |
Family
ID=36777795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2596078A Expired - Fee Related CA2596078C (en) | 2005-01-31 | 2006-01-31 | End effector for surgical instrument, surgical instrument, and method for forming the end effector |
Country Status (10)
Country | Link |
---|---|
US (1) | US20060184198A1 (en) |
EP (4) | EP2119398A3 (en) |
JP (2) | JP4907555B2 (en) |
AT (1) | ATE445361T1 (en) |
AU (2) | AU2006211127B2 (en) |
BR (1) | BRPI0606888A2 (en) |
CA (1) | CA2596078C (en) |
DE (1) | DE602006009771D1 (en) |
ES (1) | ES2333543T3 (en) |
WO (1) | WO2006083728A2 (en) |
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- 2006-01-31 EP EP09011442A patent/EP2119398A3/en not_active Withdrawn
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EP2324773A3 (en) | 2011-11-02 |
WO2006083728A2 (en) | 2006-08-10 |
DE602006009771D1 (en) | 2009-11-26 |
JP2008536530A (en) | 2008-09-11 |
EP2324773A2 (en) | 2011-05-25 |
BRPI0606888A2 (en) | 2009-07-21 |
EP1855603A2 (en) | 2007-11-21 |
JP2012071145A (en) | 2012-04-12 |
EP2119398A3 (en) | 2011-11-02 |
EP2324772A2 (en) | 2011-05-25 |
US20060184198A1 (en) | 2006-08-17 |
ATE445361T1 (en) | 2009-10-15 |
EP1855603B1 (en) | 2009-10-14 |
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