CA2602472A1 - Infusion device and method with disposable portion - Google Patents
Infusion device and method with disposable portion Download PDFInfo
- Publication number
- CA2602472A1 CA2602472A1 CA002602472A CA2602472A CA2602472A1 CA 2602472 A1 CA2602472 A1 CA 2602472A1 CA 002602472 A CA002602472 A CA 002602472A CA 2602472 A CA2602472 A CA 2602472A CA 2602472 A1 CA2602472 A1 CA 2602472A1
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- Canada
- Prior art keywords
- reservoir
- housing portion
- needle
- hollow needle
- platform
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M2005/14573—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for quick connection/disconnection with a driving system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
- A61M2207/10—Device therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/02—Holding devices, e.g. on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/14236—Screw, impeller or centrifugal type pumps
Abstract
Published without an Abstract
Claims (173)
1. A delivery device for delivering an infusion media to a user, the device comprising:
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user when the durable housing portion and the disposable housing portion are engaged.
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user when the durable housing portion and the disposable housing portion are engaged.
2. A delivery device according to claim 1, further comprising a movable needle supporting structure that allows for selective introduction of a needle into the user, for conveying infusion media from the reservoir into the user, the movable needle supporting structure being moveable relative to the disposable housing portion.
3. A delivery device according to claim 1, wherein the disposable housing portion comprises a base portion having a bottom surface and an adhesive material on the bottom surface for securing the disposable housing portion to the skin of the user.
4. A delivery device according to claim 1, wherein the disposable housing portion further comprises:
a base portion;
a bladder containing an adhesive;
a plurality of conduits connected to the bladder; and a manual operator coupled to the bladder and operable by a user to dispense adhesive from the bladder into the conduits;
wherein the plurality of conduits have openings adjacent the outside surface of the base portion.
a base portion;
a bladder containing an adhesive;
a plurality of conduits connected to the bladder; and a manual operator coupled to the bladder and operable by a user to dispense adhesive from the bladder into the conduits;
wherein the plurality of conduits have openings adjacent the outside surface of the base portion.
5. A delivery device according to claim 2, further comprising a hollow tube coupled to the moveable needle supporting structure, wherein the disposable housing portion further comprises an opening for connecting the hollow tube to the reservoir for conveying infusion media from the reservoir to the moveable needle supporting structure.
6. A delivery device according to claim 2, further comprising:
a hollow tube having first and second ends, the first end coupled to the moveable needle supporting structure; and a connector having first and second engageable and disengageable connector members, the first connector member coupled to the second end of the hollow tube and the second connector member coupled to the reservoir, the connector coupling the hollow tube in fluid flow communication with the reservoir when the first and second connector members are engaged.
a hollow tube having first and second ends, the first end coupled to the moveable needle supporting structure; and a connector having first and second engageable and disengageable connector members, the first connector member coupled to the second end of the hollow tube and the second connector member coupled to the reservoir, the connector coupling the hollow tube in fluid flow communication with the reservoir when the first and second connector members are engaged.
7. A delivery device according to claim 2, further comprising:
a hollow tube having first and second ends, the first end coupled to the moveable needle supporting structure; and a connector for connecting the second end of the hollow tube in fluid-flow communication with the reservoir, wherein the connector comprises a threaded cap having a hollow needle for coupling to a corresponding reservoir connector structure.
a hollow tube having first and second ends, the first end coupled to the moveable needle supporting structure; and a connector for connecting the second end of the hollow tube in fluid-flow communication with the reservoir, wherein the connector comprises a threaded cap having a hollow needle for coupling to a corresponding reservoir connector structure.
8. A delivery device according to claim 7, wherein the corresponding reservoir connector structure comprises a septum for receiving an end of the hollow needle.
9. A delivery device according to claim 1, further comprising a sensor and a sensor lead connecting the sensor to the electrical control circuitry in the durable portion.
10. A delivery device according to claim 9, wherein the sensor comprises a biological or environmental sensing device.
11. A delivery device according to claim 10, wherein the sensor comprises a disposable needle pad that further comprises a needle for piercing the user's skin and electronics reactive to a biological condition.
12. A delivery device according to claim 11, wherein the electrical control circuitry in the durable housing portion includes sensor electronics and wherein the disposable needle pad of the sensor is in electrical communication with the sensor lead to convey electrical signals from the sensor to the sensor electronics.
13. A delivery device according to claim 1, wherein the durable portion contains wireless communication electronics for providing wireless communication with a sensor located remote from the delivery device.
14. A delivery device according to claim 1, wherein the delivery device further comprises a biological sensor for providing an electrical characteristic dependent upon a biological condition and the durable portion further comprises sensor electronics connected to the biological sensor for sensing a biological condition based on the electrical characteristic of the biological sensor.
15. A method for delivering an infusion media to a user, the method comprising:
securing a disposable housing portion to a user;
attaching a durable housing portion to the disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the disposable housing portion;
supporting a reservoir for containing infusion media on the disposable housing portion; and containing electrical control circuitry in the durable housing portion for controlling the delivery of infusion media from the reservoir to the user.
securing a disposable housing portion to a user;
attaching a durable housing portion to the disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the disposable housing portion;
supporting a reservoir for containing infusion media on the disposable housing portion; and containing electrical control circuitry in the durable housing portion for controlling the delivery of infusion media from the reservoir to the user.
16. A method as recited in claim 15, further comprising:
depleting the reservoir of infusion media;
detaching the durable housing portion from the disposable housing portion;
replacing the disposable housing portion with a further disposable housing portion having a sufficiently filled reservoir; and attaching the durable housing portion to the further disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the further disposable housing portion.
depleting the reservoir of infusion media;
detaching the durable housing portion from the disposable housing portion;
replacing the disposable housing portion with a further disposable housing portion having a sufficiently filled reservoir; and attaching the durable housing portion to the further disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the further disposable housing portion.
17. A method as recited in claim 15, further comprising connecting a needle supporting structure in fluid flow communication with the reservoir, the needle supporting structure for selective introduction of a needle into the user.
18. A method as recited in claim 15, further comprising providing an adhesive material on a bottom surface of the disposable housing portion for securing the disposable housing portion to the skin of the user.
19. A method according to claim 15, further comprising:
containing a flowable adhesive in a bladder;
coupling a plurality of conduits in flow communication with the bladder;
coupling a manual operator to the bladder for dispensing adhesive from the bladder into the conduits in response to a manual operation of the manual operator;
wherein the plurality of conduits have openings adjacent the outside surface of the disposable base portion.
containing a flowable adhesive in a bladder;
coupling a plurality of conduits in flow communication with the bladder;
coupling a manual operator to the bladder for dispensing adhesive from the bladder into the conduits in response to a manual operation of the manual operator;
wherein the plurality of conduits have openings adjacent the outside surface of the disposable base portion.
20. A method as recited in claim 15, further comprising connecting a hollow tube to the reservoir for conveying infusion media from the reservoir to the user.
21. A method according to claim 16, further comprising:
coupling a first end of a hollow tube to the needle supporting structure; and coupling a second end of the hollow tube to a first connector member of a connector;
coupling a second connector member of a connector to the reservoir, the second connector member being engageable and disenageable with the first connector member of the connector, such that the connector couples the hollow tube in fluid flow communication with the reservoir when the first and second connector members are engaged.
coupling a first end of a hollow tube to the needle supporting structure; and coupling a second end of the hollow tube to a first connector member of a connector;
coupling a second connector member of a connector to the reservoir, the second connector member being engageable and disenageable with the first connector member of the connector, such that the connector couples the hollow tube in fluid flow communication with the reservoir when the first and second connector members are engaged.
22. A method according to claim 16, further comprising:
coupling a first end of a hollow tube to the needle supporting structure; and coupling a connector to the second end of the hollow tube, the connector for selectively coupling the second end of the hollow tube in fluid flow communication with the reservoir;
wherein the connector comprises a threaded cap having a hollow needle for coupling to a corresponding reservoir connector structure.
coupling a first end of a hollow tube to the needle supporting structure; and coupling a connector to the second end of the hollow tube, the connector for selectively coupling the second end of the hollow tube in fluid flow communication with the reservoir;
wherein the connector comprises a threaded cap having a hollow needle for coupling to a corresponding reservoir connector structure.
23. A method according to claim 22, wherein the corresponding reservoir connector structure comprises a septum for receiving an end of the hollow needle.
24. A method as recited in claim 15, further comprising connecting the durable portion to a biological or environmental sensor through a sensor lead.
25. A method according to claim 24, wherein the sensor comprises a disposable needle pad that further comprises a needle for piercing the user's skin and electronics reactive to a biological condition.
26. A method according to claim 15, further comprising containing wireless communication electronics in the durable housing portion for providing wireless communication with a sensor located remote from the delivery device.
27. A method according to claim 15, connecting a biological sensor to the control electronics, the biological sensor for providing an electrical characteristic dependent upon a biological condition; containing sensor electronics in the durable housing portion; and connecting the sensor electronics to the biological sensor for sensing a biological condition based on the electrical characteristic of the biological sensor.
28. A medical system for securing to a user, the system comprising:
a housing having a base adapted to be secured to a user;
a medical device supported by the housing for operatively coupling to a user when the base is secured to the user;
an adhesive reservoir supported by the housing, the adhesive reservoir for containing a flowable adhesive media; and a conduit system supported by the housing and connected with the second reservoir for conveying adhesive media from the second reservoir to the base of the housing.
a housing having a base adapted to be secured to a user;
a medical device supported by the housing for operatively coupling to a user when the base is secured to the user;
an adhesive reservoir supported by the housing, the adhesive reservoir for containing a flowable adhesive media; and a conduit system supported by the housing and connected with the second reservoir for conveying adhesive media from the second reservoir to the base of the housing.
29. A medical system as recited in claim 28, wherein the medical device comprises an infusion delivery device having an infusion media reservoir for containing an infusion media and a needle for insertion into a user's skin when the base of the housing is secured to the user.
30. A medical system as recited in claim 28, further comprising a manual operator adapted to be manually operated by a user for selectively dispensing adhesive media from the adhesive reservoir into the conduit system.
31. A medical system as recited in claim 28, wherein the conduit system comprises a plurality of conduits, each having an open end arranged adjacent the base of the housing.
32. A medical system as recited in claim 31. wherein the base has a plurality of pores for conveying adhesive media dispensed from the open ends of the conduits.
33. A medical system as recited in claim 32, wherein the base of the housing has an outer peripheral edge, and wherein said pores are arranged to convey adhesive media around the outer peripheral edge of the base.
34. A delivery device for delivering an infusion media to a user, the device comprising:
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion;
electrical control circuitry and a drive device contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user and wherein the drive device operatively couples to the reservoir to drive infusion media from the reservoir under control of the electrical control circuitry when the durable housing portion is engaged with the disposable housing portion.
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion;
electrical control circuitry and a drive device contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user and wherein the drive device operatively couples to the reservoir to drive infusion media from the reservoir under control of the electrical control circuitry when the durable housing portion is engaged with the disposable housing portion.
35. A delivery device according to claim 34, wherein the durable housing portion contains a drive linkage, wherein the drive device is coupled to the drive linkage and wherein the drive linkage is operatively coupled to the reservoir for driving fluid out of the reservoir under control of the electrical control circuitry when the durable housing portion is engaged with the disposable housing portion.
36. A delivery device according to claim 34, wherein the drive device comprises an electrical motor.
37. A delivery device according to claim 35, wherein the drive linkage comprises a gear train and a threaded shaft attached to an outermost gear of the gear train away from the drive device, wherein the gear train provides a rotating action to the threaded shaft.
38. A delivery device according to claim 35, wherein:
the drive linkage comprises a threaded shaft coupled to the drive device for rotation;
the reservoir comprises a container and a moveable member disposed at least partially within the container and moveable to drive infusion media out of the container, the moveable member having one of the group consisting of a threaded seat, a keyed seat, and a slotted seat engageable with the threaded shaft of the drive device;
the seat on the moveable member of the reservoir operatively couples with the threaded shaft of the drive device when the disposable housing portion and the durable housing portion are engaged, and wherein the threaded shaft is configured to separate from the seat of the moveable member when the disposable housing portion and the durable housing portion are disengaged.
the drive linkage comprises a threaded shaft coupled to the drive device for rotation;
the reservoir comprises a container and a moveable member disposed at least partially within the container and moveable to drive infusion media out of the container, the moveable member having one of the group consisting of a threaded seat, a keyed seat, and a slotted seat engageable with the threaded shaft of the drive device;
the seat on the moveable member of the reservoir operatively couples with the threaded shaft of the drive device when the disposable housing portion and the durable housing portion are engaged, and wherein the threaded shaft is configured to separate from the seat of the moveable member when the disposable housing portion and the durable housing portion are disengaged.
39. A delivery device according to claim 35, wherein the drive linkage further comprises a shaft having first and second ends and a drive screw, and wherein the first end of the shaft is coupled to the drive device for rotation by the drive device, the second end of the shaft is coupled to the drive screw for rotation therewith and the drive screw is coupled to the reservoir for driving infusion media from the reservoir upon rotation of the drive screw.
40. A delivery device according to claim 39, wherein the reservoir further comprises a piston plunger having a longitudinal dimension and a single rack having threads extending along the longitudinal dimension of the piston plunger, wherein the threads of the single rack operatively couple with the drive screw of the drive device for rotation therewith when the disposable housing portion and the durable housing portion are engaged.
41. A delivery device according to claim 35, wherein:
the drive linkage comprises a shaft and pinion gear coupled to the drive device for rotation of the pinion gear; and the reservoir comprises a container and a moveable plunger disposed at least partially within the container and moveable to drive infusion media out of the container, the plunger being operatively coupled with the pinion gear to move the plunger upon rotation of the pinion gear.
the drive linkage comprises a shaft and pinion gear coupled to the drive device for rotation of the pinion gear; and the reservoir comprises a container and a moveable plunger disposed at least partially within the container and moveable to drive infusion media out of the container, the plunger being operatively coupled with the pinion gear to move the plunger upon rotation of the pinion gear.
42. A delivery device according to claim 41, wherein the plunger comprises a single threaded rack that operatively couples to the pinion gear to be moveably driven with rotation of the pinion gear by the drive device when the disposable housing portion and the durable housing portion are engaged.
43. A delivery device according to claim 35, wherein:
the drive linkage comprises two shafts and two pinion gears, each pinion gear coupled to a respective shaft, the shafts further coupled to the drive device for rotation of the shafts and pinion gears; and the reservoir comprises a container and a moveable plunger disposed at least partially within the container and moveable to drive infusion media out of the container, the plunger being operatively coupled with the two pinion gears to move the plunger upon rotation of the pinion gears.
the drive linkage comprises two shafts and two pinion gears, each pinion gear coupled to a respective shaft, the shafts further coupled to the drive device for rotation of the shafts and pinion gears; and the reservoir comprises a container and a moveable plunger disposed at least partially within the container and moveable to drive infusion media out of the container, the plunger being operatively coupled with the two pinion gears to move the plunger upon rotation of the pinion gears.
44. A delivery device according to claim 43, wherein the plunger comprises two threaded racks that operatively couple to the pinion gears to be moveably driven with rotation of the pinion gears by the drive device when the disposable housing portion and the durable housing portion are engaged.
45. A delivery device according to claim 39, wherein the reservoir comprises a piston plunger with a hollow, threaded interior along a longitudinal direction of the piston plunger, wherein the threaded interior is threaded to correspond to the drive screw of the drive device, and wherein the threaded interior operatively couples with the drive screw of the drive device when the disposable housing portion and the durable housing portion are engaged.
46. A delivery device according to claim 34, wherein the drive device comprises a threaded drive shaft screw and wherein the reservoir comprises a container and a piston plunger moveable within the container, the piston plunger having a pair of pivotal arm members extending longitudinally out of the container in a V-configuration, wherein each arm member comprises a threaded foot portion extending toward the threaded drive shaft screw of the drive device, and wherein the delivery device further comprises cam surfaces arranged relative to the reservoir for pivoting the arm members toward the threaded screw to engage the threaded foot portions of the arm members with the threaded screw.
47. A delivery device according to claim 46, wherein:
the reservoir and the piston plunger are supported for rotation;
the arm members operatively couple with the drive shaft screw of the drive device when the reservoir and the piston plunger are rotated in a direction allowing the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are engaged; and the arm members and the drive shaft screw allow for separation of the reservoir and the drive device when the reservoir and the piston plunger are rotated in a direction opposite to the direction that allows the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are disengaged.
the reservoir and the piston plunger are supported for rotation;
the arm members operatively couple with the drive shaft screw of the drive device when the reservoir and the piston plunger are rotated in a direction allowing the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are engaged; and the arm members and the drive shaft screw allow for separation of the reservoir and the drive device when the reservoir and the piston plunger are rotated in a direction opposite to the direction that allows the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are disengaged.
48. A method for delivering an infusion media to a user, the method comprising:
securing a disposable housing portion to a user;
attaching a durable housing portion to the disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the disposable housing portion;
supporting a reservoir for containing infusion media on the disposable housing portion; and containing electrical control circuitry and a drive device in the durable housing portion for controlling the delivery of infusion media from the reservoir to the user when the durable housing portion and the disposable housing portion are engaged.
securing a disposable housing portion to a user;
attaching a durable housing portion to the disposable housing portion in a manner that allows a user to selectively detach the durable housing portion from the disposable housing portion;
supporting a reservoir for containing infusion media on the disposable housing portion; and containing electrical control circuitry and a drive device in the durable housing portion for controlling the delivery of infusion media from the reservoir to the user when the durable housing portion and the disposable housing portion are engaged.
49. A method according to claim 48, further comprising:
containing a drive linkage in the durable housing portion; and coupling the drive linkage to the reservoir for driving fluid out of the reservoir when the durable housing portion is engaged with the disposable housing portion.
containing a drive linkage in the durable housing portion; and coupling the drive linkage to the reservoir for driving fluid out of the reservoir when the durable housing portion is engaged with the disposable housing portion.
50. A method according to claim 48, wherein the drive device comprises an electrical motor.
51. A method according to claim 49, wherein the drive linkage comprises a gear train and a threaded shaft attached to an outermost gear of the gear train away from the drive device, and wherein the method further comprises rotating the gear train with the drive device and rotating the threaded shaft with the gear train.
52. A method according to claim 49, wherein:
containing a drive linkage in the durable housing comprises coupling a threaded shaft to the drive device for rotation by the drive device;
supporting a reservoir comprises supporting a container and a moveable member in the disposable housing portion, the moevable member being moveable within the container and to drive infusion media out of the container, the moveable member having one of the group consisting of a threaded seat, a keyed seat, and a slotted seat engageable with the threaded shaft of the drive device; operatively coupling the seat on the moveable member of the reservoir with the threaded shaft when the disposable housing portion and the durable housing portion are engaged, and separating the threaded shaft from the seat of the moveable member when the disposable housing portion and the durable housing portion are disengaged.
containing a drive linkage in the durable housing comprises coupling a threaded shaft to the drive device for rotation by the drive device;
supporting a reservoir comprises supporting a container and a moveable member in the disposable housing portion, the moevable member being moveable within the container and to drive infusion media out of the container, the moveable member having one of the group consisting of a threaded seat, a keyed seat, and a slotted seat engageable with the threaded shaft of the drive device; operatively coupling the seat on the moveable member of the reservoir with the threaded shaft when the disposable housing portion and the durable housing portion are engaged, and separating the threaded shaft from the seat of the moveable member when the disposable housing portion and the durable housing portion are disengaged.
53. A method according to claim 49, wherein containing a drive linkage in the durable housing portion comprises:
containing a shaft having and a drive screw in the durable housing portion;
coupling the shaft to the drive device for rotation by the drive device;
coupling the shaft to the drive screw for rotation therewith; and coupling the drive screw to the reservoir for driving infusion media from the reservoir upon rotation of the drive screw.
containing a shaft having and a drive screw in the durable housing portion;
coupling the shaft to the drive device for rotation by the drive device;
coupling the shaft to the drive screw for rotation therewith; and coupling the drive screw to the reservoir for driving infusion media from the reservoir upon rotation of the drive screw.
54. A method according to claim 53, wherein the reservoir comprises a container and a piston plunger having a longitudinal dimension and a single rack having threads extending along the longitudinal dimension, wherein the method further comprises coupling the threads of the single rack operatively with the drive screw for rotation therewith when the disposable housing portion and the durable housing portion are engaged.
55. A method according to claim 49, wherein:
containing a drive linkage in the durable housing portion comprises containing a shaft having a pinion gear on one end in the durable housing portion and coupling the pinion gear to the drive device for rotation of the pinion gear by the drive device;
and supporting a reservoir comprises supporting a container and a moveable plunger on the disposable housing portion, the moveable plunger located at least partially within the container and moveable to drive infusion media out of the container; and operatively coupling the moveable plunger with the pinion gear to move the plunger upon rotation of the pinion gear.
containing a drive linkage in the durable housing portion comprises containing a shaft having a pinion gear on one end in the durable housing portion and coupling the pinion gear to the drive device for rotation of the pinion gear by the drive device;
and supporting a reservoir comprises supporting a container and a moveable plunger on the disposable housing portion, the moveable plunger located at least partially within the container and moveable to drive infusion media out of the container; and operatively coupling the moveable plunger with the pinion gear to move the plunger upon rotation of the pinion gear.
56. A method according to claim 55, wherein the plunger comprises a single threaded rack and wherein operatively coupling the moveable plunger with the pinion gear comprises engaging the pinion gear and the single threaded rack and moving the single threaded rack of the plunger with rotation of the pinion gear by the drive device when the disposable housing portion and the durable housing portion are engaged.
57. A method according to claim 49, wherein:
containing a drive linkage in the durable housing portion comprises containing two shafts and two pinion gears in the durable housing portion with each pinion gear coupled to a respective shaft, and coupling the shafts to the drive device for rotation of the shafts and pinion gears; and supporting a reservoir comprises supporting a container and a moveable plunger on the disposable housing portion, the moveable plunger being located at least partially within the container and moveable to drive infusion media out of the container; and operatively coupling the moveable plunger to the two pinion gears to move the plunger upon rotation of the pinion gears.
containing a drive linkage in the durable housing portion comprises containing two shafts and two pinion gears in the durable housing portion with each pinion gear coupled to a respective shaft, and coupling the shafts to the drive device for rotation of the shafts and pinion gears; and supporting a reservoir comprises supporting a container and a moveable plunger on the disposable housing portion, the moveable plunger being located at least partially within the container and moveable to drive infusion media out of the container; and operatively coupling the moveable plunger to the two pinion gears to move the plunger upon rotation of the pinion gears.
58. A method according to claim 57, wherein the plunger comprises two threaded racks that operatively couple to the pinion gears to be moveably driven with rotation of the pinion gears by the drive device when the disposable housing portion and the durable housing portion are engaged.
59. A method according to claim 53, wherein the reservoir comprises a piston plunger with a hollow, threaded interior along a longitudinal direction of the piston plunger, wherein the threaded interior is threaded to correspond to the drive screw of the drive device, and wherein the method further comprises operatively coupling the threaded interior with the drive screw of the drive device when the disposable housing portion and the durable housing portion are engaged.
60. A method according to claim 49, wherein containing a drive device and drive linkage comprises containing a threaded drive shaft screw in the durable housing portion and wherein supporting a reservoir comprises supporting a container and a piston plunger on the disposable housing portion, the piston plunger being moveable within the container, the piston plunger having a pair of pivotal arm members extending longitudinally out of the container in a V-configuration, wherein each arm member comprises a threaded foot portion extending toward the threaded drive shaft screw of the drive device, and wherein the method further comprises supporting cam surfaces relative to the threaded screw for contacting and pivoting the arm members toward the threaded screw to selectively engage the threaded foot portions of the arm members with the threaded screw.
61. A method according to claim 60, further comprising:
supporting the reservoir and the piston plunger for rotation;
operatively coupling the arm members with the drive shaft screw of the drive device when the reservoir and the piston plunger are rotated in a direction allowing the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are engaged; and separating the arm members and the drive shaft screw when the reservoir and the piston plunger are rotated in a direction opposite to the direction that allows the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are disengaged.
supporting the reservoir and the piston plunger for rotation;
operatively coupling the arm members with the drive shaft screw of the drive device when the reservoir and the piston plunger are rotated in a direction allowing the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are engaged; and separating the arm members and the drive shaft screw when the reservoir and the piston plunger are rotated in a direction opposite to the direction that allows the cam surfaces to engage the arm members and the drive shaft screw and when the disposable housing portion and the durable housing portion are disengaged.
62. A delivery device for delivering an infusion media to a user, the device comprising:
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion, wherein the reservoir comprises a container and a septum at one end of the container;
a pump assembly that is operatively coupled to the reservoir for fluid-flow communication with the reservoir container, the pump assembly comprising a pump housing portion that contains a pump chamber, a rotary pump blade supported for rotation within the pump chamber, a receptacle having a size and shape for receiving the septum of the reservoir, the receptacle being in fluid flow communication with the pump chamber;
a drive device for rotatably driving the rotary pump blade within the pump chamber to impart a fluid flow force directed to convey fluid from the reservoir, through the pump chamber, when the septum of the reservoir is received in the receptacle of the pump housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion;
a reservoir for containing infusion media supported on the disposable housing portion, wherein the reservoir comprises a container and a septum at one end of the container;
a pump assembly that is operatively coupled to the reservoir for fluid-flow communication with the reservoir container, the pump assembly comprising a pump housing portion that contains a pump chamber, a rotary pump blade supported for rotation within the pump chamber, a receptacle having a size and shape for receiving the septum of the reservoir, the receptacle being in fluid flow communication with the pump chamber;
a drive device for rotatably driving the rotary pump blade within the pump chamber to impart a fluid flow force directed to convey fluid from the reservoir, through the pump chamber, when the septum of the reservoir is received in the receptacle of the pump housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
63. A delivery device according to claim 62, wherein the rotary pump blade is supported on a drive axel and wherein the drive device comprises a motor and a drive gear coupled to the drive axel for rotation of the drive axel by the motor.
64. A delivery device according to claim 62, further comprising a drive axel supporting the rotary pump blade for rotation within the pump chamber, the drive axel extending through a wall of the pump housing portion and having an external end located external to the pump housing portion for engaging the drive device.
65. A delivery device according to claim 64, further comprising a gear coupled to the external end of the drive axel for engaging the drive device.
66. A delivery device according to claim 62, wherein the pump assembly further comprises a hollow needle having a sharp end located within the receptacle and facing toward an open end of the receptacle for piercing the septum of a reservoir when a reservoir septum is received within the receptacle, the hollow needle provided in fluid flow communication with the pump chamber.
67. A delivery device according to claim 62, further comprising an outlet chamber in fluid flow communication with the pump chamber, for receiving fluid from the pump chamber.
68. A delivery device according to claim 62, wherein the pump assembly further comprises a hollow needle having a sharp end located within the receptacle, the hollow needle provided in fluid flow communication with the pump chamber; wherein the pump assembly couples to the reservoir by manually pushing the receptacle end of the pump housing over the septum of the reservoir until the hollow needle pierces the septum on the reservoir and partially extends into the reservoir for fluid flow communication between the interior of the reservoir.
69. A delivery device according to claim 62, further comprising an outlet chamber in fluid flow communication with the pump chamber and having an opening for conveying infusion media out of the pump assembly.
70. A delivery device according to claim 62, wherein the pump housing portion has an outlet end and a septum structure on the outlet end for allowing a hollow needle to extend through the septum structure to provide a fluid flow path out from the outlet end of the pump housing portion.
71. A delivery device according to claim 70, wherein the septum structure comprises a pair of septa arranged across from each other on opposing sides of the pump housing portion for allowing a hollow needle to pass through both septa, and wherein the hollow needle has a side opening that provides a fluid flow path for the fluid within the outlet chamber end of the housing to a location outside of the outlet chamber when hollow needle is passed through the septa.
72. A delivery device according to claim 71, wherein the hollow needle further comprises a head with a surface on which a force may be applied to move the hollow needle through the septa.
73. A pump assembly for coupling to a reservoir container that contains a flowable medium, the pump assembly comprising:
a pump housing portion that contains a pump chamber;
a rotary pump blade supported for rotation within the pump chamber;
a receptacle having a size and shape for receiving one end of a reservoir, the receptacle being in fluid flow communication with the pump chamber;
a flow communicator located within the receptacle for providing a flow path for communication of a flowable medium from a reservoir to the pump chamber when one end of the reservoir is received within the receptacle.
a pump housing portion that contains a pump chamber;
a rotary pump blade supported for rotation within the pump chamber;
a receptacle having a size and shape for receiving one end of a reservoir, the receptacle being in fluid flow communication with the pump chamber;
a flow communicator located within the receptacle for providing a flow path for communication of a flowable medium from a reservoir to the pump chamber when one end of the reservoir is received within the receptacle.
74. A pump assembly as recited in claim 73, wherein the reservoir to which the pump assembly couples is provided with a septum structure and wherein the flow communicator comprises a needle arranged within the receptacle to pierce the septum structure of a reservoir when the one end of the reservoir is received within the receptacle.
75. A pump assembly as recited in claim 73, wherein the reservoir to which the pump assembly couples is provided with a septum structure and wherein the flow communicator comprises a needle located within the receptacle and having a sharp end directed toward an open end of the receptacle and wherein the open end of the receptacle is of a size and shape for receiving the one end of the reservoir such that the sharp end of the needle pierces the septum structure of the reservoir during an action of inserting the reservoir into the open end of the receptacle.
76. A pump assembly as recited in claim 73, further comprising a drive axel for rotably supporting the rotary pump blade, the drive axel is configured to be operatively coupled to a drive device for rotation of the drive axel by the drive device.
77. A pump assembly as recited in claim 73, further comprising a drive axel supporting the rotary pump blade for rotation within the pump chamber, the drive axel extending through a wall of the pump housing portion and having an external end located external to the pump housing portion for engaging a drive device.
78. A pump assembly according to claim 77, further comprising a gear coupled to the external end of the drive axel for engaging the drive device.
79. A pump assembly according to claim 73, further comprising an outlet chamber in fluid flow communication with the pump chamber, for receiving fluid from the pump chamber.
80. A pump assembly according to claim 73, wherein the flow communicator comprises a needle arranged within the receptacle to extend into a reservoir when the one end of the reservoir is received within the receptacle; wherein the pump assembly couples to the reservoir by manually pushing the receptacle of the pump housing over one end of the reservoir until the needle partially extends into the reservoir for fluid flow communication with the interior of the reservoir.
81. A pump assembly according to claim 73, wherein the further comprising an outlet chamber in fluid flow communication with the pump chamber and having an opening for conveying infusion media out of the pump housing portion.
82. A pump assembly according to claim 73, wherein the pump housing portion has an outlet end and a septum structure on the outlet end for allowing a hollow needle to extend through the septum structure to provide a fluid flow path out from the outlet end of the pump housing portion.
83. A pump assembly according to claim 82, wherein the septaum structure comprises a pair of septa arranged across from each other on opposing sides of the pump housing portion for allowing a hollow needle to pass through both septa, and wherein the hollow needle has a side opening that provides a fluid flow path for the fluid within the outlet chamber end of the housing to a location outside of the outlet chamber when hollow needle is passed through the septa.
84. A pump assembly according to claim 83, wherein the hollow needle further comprises a head with a surface on which a force may be applied to move the hollow needle through the septa.
85. A method for delivering an infusion media to a user, the method comprising:
providing a housing portion adapted to be secured to a user;
supporting a reservoir for containing infusion media on the housing portion, wherein the reservoir comprises a container and a septum at one end of the container;
coupling a pump assembly to the reservoir for fluid-flow communication with the reservoir container, the pump assembly comprising a pump housing portion that contains a pump chamber;
supporting a rotary pump blade for rotation within the pump chamber;
providing a receptacle in fluid flow communication with the pump chamber, the receptacle having a size and shape for receiving the septum of the reservoir;
coupling the rotary pump blade with a drive device for rotatably driving the rotary pump blade within the pump chamber to impart a fluid flow force directed to convey fluid from the reservoir, through the pump chamber, when the septum of the reservoir is received in the receptacle of the pump housing portion.
providing a housing portion adapted to be secured to a user;
supporting a reservoir for containing infusion media on the housing portion, wherein the reservoir comprises a container and a septum at one end of the container;
coupling a pump assembly to the reservoir for fluid-flow communication with the reservoir container, the pump assembly comprising a pump housing portion that contains a pump chamber;
supporting a rotary pump blade for rotation within the pump chamber;
providing a receptacle in fluid flow communication with the pump chamber, the receptacle having a size and shape for receiving the septum of the reservoir;
coupling the rotary pump blade with a drive device for rotatably driving the rotary pump blade within the pump chamber to impart a fluid flow force directed to convey fluid from the reservoir, through the pump chamber, when the septum of the reservoir is received in the receptacle of the pump housing portion.
86. A method according to claim 85, wherein supporting a rotary pump blade comprises supporting the rotary pump blade on a drive axel and wherein the drive device comprises a motor coupled to the drive axel for rotation of the drive axel by the motor.
87. A method according to claim 85, wherein supporting a rotary pump blade comprises coupling a drive axel to the rotary pump blade, supporting the rotary pump blade on the drive axel for rotation within the pump chamber, extending the drive axel through a wall of the pump housing portion and engaging an external end of the drive axel located external to the pump housing portion with the drive device.
88. A method according to claim 85, wherein providing a receptacle comprises providing a receptacle with an open end and a hollow needle having a sharp end located within the receptacle and facing toward the open end of the receptacle for piercing the septum of a reservoir when a reservoir septum is received within the receptacle, the hollow needle provided in fluid flow communication with the pump chamber.
89. A method according to claim 85, further comprising arranging an outlet chamber in fluid how communication with the pump chamber for receiving fluid from the pump chamber.
90. A method according to claim 85, wherein providing a receptacle comprises providing a receptacle having a hollow needle with a sharp end for coupling to the reservoir by manually pushing the receptacle of the pump housing over the septum of the reservoir until the hollow needle pierces the septum on the reservoir and partially extends into the reservoir for fluid flow communication between the interior of the reservoir.
91. A method according to claim 85, further comprising providing a septum structure on an outlet end of the pump housing for allowing a hollow needle to extend through the septum structure to provide a fluid flow path out from the outlet end of the pump housing portion.
92. A method according to claim 91, wherein providing a septum structure comprises providing a pair of septa arranged across from each other on opposing sides of the pump housing portion for allowing a hollow needle to pass through both septa, and providing a hollow needle with a side opening that provides a fluid flow path for the fluid within the outlet chamber end of the housing to a location outside of the outlet chamber when hollow needle is passed through the septa.
93. A delivery device for delivering an infusion media to a user, the device comprising:
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media;
a moveable platform on the disposable housing portion for supporting the reservoir for movement relative to the disposable housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
a disposable housing portion adapted to be secured to a user;
a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion;
a reservoir for containing infusion media;
a moveable platform on the disposable housing portion for supporting the reservoir for movement relative to the disposable housing portion;
electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
94. A delivery device according to claim 93, further comprising a plurality of struts for moveably supporting the platform and selectively locking the platform in a fixed position relative to the disposable housing portion, wherein the platform is moveably supported by the struts when the platform is in a first position relative to the struts and wherein the platform is locked in a fixed location relative to the disposable housing portion when the platform is moved into a second position relative to the struts.
95. A delivery device according to claim 94, wherein each of the struts include a projection that engages the platform in a snap-fit arrangement when the platform is moved into the second position, and wherein the projections are disengaged from the platform when the platform is in the first position.
96. A delivery device according to claim 95, wherein the platform has an upper surface for engaging the strut projections when the platform is in the second position.
97. A delivery device according to claim 94, wherein, when the platform is in the first position relative to the struts, the platform is moveable toward the disposable housing portion to the second position relative to the struts and wherein the struts include a projection that engages the platform in a snap-fit arrangement, when the platform is moved into the second position relative to the struts.
98. A delivery device according to claim 94, further comprising a spring arranged to urge the platform in the direction toward the first position of the platform relative to the struts.
99. A delivery device according to claim 98, wherein the spring is located between the platform and the disposable housing portion to urge the platform in a direction away from the disposable housing portion.
100. A delivery device according to claim 93, further comprising a hollow needle supported relative to the platform to extend at least partially into the reservoir when the reservoir is supported on the platform.
101. A delivery device according to claim 100, wherein the hollow needle is attached to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform.
102. A delivery device according to claim 93, further comprising a hollow needle that has a first end adapted to be extended at least partially into the reservoir when the reservoir is supported on the platform, the hollow needle having a second end having a sharp tip adapted to pierce the skin of a user when the platform is moved into a second position.
103. A delivery device according to claim 93, wherein the disposable housing portion has a base provided with an opening, the delivery device further comprising a hollow needle that has a first end adapted to be extended at least partially into the reservoir when the reservoir is supported on the platform, the hollow needle having a second end having a sharp tip adapted to extend through the opening in the base when the platform is moved into a second position.
104. A delivery device according to claim 102, wherein the hollow needle is attached to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform and wherein the hollow needle moves into the second position in conjunction with the movement of the platform from the first position of the platform to the second position of the platform.
105. A delivery device for delivering an infusion media to a user, the device comprising:
a housing having a base portion adapted to be secured to a user;
a reservoir for containing infusion media, the reservoir supported by the housing;
a drive device and electrical control circuitry contained in the housing for providing a controlled delivery of infusion media from the reservoir to the user;
a platform contained in the housing for receiving and supporting the reservoir;
a plurality of struts for moveably supporting the platform and selectively locking the platform in a fixed position relative to the base of the housing, wherein the platform is moveably supported by the struts when the platform is in a first position relative to the struts and wherein the platform is locked in a fixed location relative to the base of the housing when the platform is moved into a second position relative to the struts.
a housing having a base portion adapted to be secured to a user;
a reservoir for containing infusion media, the reservoir supported by the housing;
a drive device and electrical control circuitry contained in the housing for providing a controlled delivery of infusion media from the reservoir to the user;
a platform contained in the housing for receiving and supporting the reservoir;
a plurality of struts for moveably supporting the platform and selectively locking the platform in a fixed position relative to the base of the housing, wherein the platform is moveably supported by the struts when the platform is in a first position relative to the struts and wherein the platform is locked in a fixed location relative to the base of the housing when the platform is moved into a second position relative to the struts.
106. A delivery device according to claim 105, wherein each of the struts include a projection that engages the platform in a snap-fit arrangement when the platform is moved into the second position, and wherein the projections are disengaged from the platform when the platform is in the first position.
107. A delivery device according to claim 105, wherein, when the platform is in the first position relative to the struts, the platform is moveable toward the base of the housing to the second position relative to the struts and wherein the struts include a projection that engages the platform in a snap-fit arrangement, when the platform is moved into the second position relative to the struts.
108. A delivery device according to claim 105, further comprising a spring arranged to urge the platform in the direction toward the first position of the platform relative to the struts.
109. A delivery device according to claim 108, wherein the spring is located between the platform and the base of the housing to urge the platform in a direction away from the base of the housing.
110. A delivery device according to claim 105, further comprising a hollow needle supported relative to the platform to extend at least partially into the reservoir when the reservoir is supported on the platform.
111. A delivery device according to claim 110, wherein the hollow needle is attached to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform.
112. A delivery device according to claim 105, further comprising a hollow needle that has a first end adapted to be extended at least partially into the reservoir when the reservoir is supported on the platform , the hollow needle having a second end having a sharp tip adapted to pierce the skin of a user when the platform is moved into a second position relative to the struts.
113. A delivery device according to claim 105, wherein the base of the housing is provided with an opening, the device further comprising a hollow needle that has a first end adapted to be extended at least partially into the reservoir when the reservoir is supported on the platform, the hollow needle having a second end having a sharp tip adapted to extend through the opening in the base when the platform is moved into a second position relative to the struts.
114. A delivery device according to claim 113, wherein the hollow needle is attached to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform and wherein the hollow needle moves into the second position in conjunction with the movement of the platform from the first position of the platform to the second position of the platform relative to the struts.
115. A method for delivering an infusion media to a user, the device comprising:
providing a housing having a base portion adapted to be secured to a user;
supporting a platform for movement on the base portion of the housing;
supporting a reservoir for containing infusion media on the platform;
containing a drive device and electrical control circuitry in the housing for providing a controlled delivery of infusion media from the reservoir to the user;
wherein supporting a platform comprises providing a plurality of struts, supporting the platform on the struts for movement between first and second positions relative to the struts, and locking the platform in a fixed location relative to the base of the housing when the platform is moved into a second position relative to the struts.
providing a housing having a base portion adapted to be secured to a user;
supporting a platform for movement on the base portion of the housing;
supporting a reservoir for containing infusion media on the platform;
containing a drive device and electrical control circuitry in the housing for providing a controlled delivery of infusion media from the reservoir to the user;
wherein supporting a platform comprises providing a plurality of struts, supporting the platform on the struts for movement between first and second positions relative to the struts, and locking the platform in a fixed location relative to the base of the housing when the platform is moved into a second position relative to the struts.
116. A method according to claim 115, wherein locking the platform in a fixed location relative to the base comprises engaging the platform with a projections on the plurality of struts in a snap-fit arrangement when the platform is moved into the second position.
117. A method according to claim 115, wherein locking the platform in a fixed location relative to the base comprises moving the platform from the first position to the second position and engaging the platform with projections on the struts automatically as the platform is moved into the second position relative to the struts.
118. A method according to claim 115, further comprising spring biasing the platform in the direction toward the first position of the platform relative to the struts.
119. A method according to claim 118, wherein spring biasing the platform comprises locating a spring between the platform and the base of the housing to urge the platform in a direction away from the base of the housing.
120. A method according to claim 115, further comprising supporting a hollow needle relative to the platform to extend at least partially into the reservoir when the reservoir is supported on the platform.
121. A method according to claim 120, wherein supporting a hollow needle comprises fixing the hollow needle to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform.
122. A method according to claim 115, further comprising arranging a first end of a hollow needle to extend at least partially into the reservoir when the reservoir is supported on the platform, arranging a second end of the hollow needle to pierce the skin of a user when the platform is moved into a second position relative to the struts.
123. A method according to claim 115, further comprising providing an opening in the base of the housing, arranging a first end of a hollow needle to extend at least partially into the reservoir when the reservoir is supported on the platform, and moving the hollow needle such that a second end of the hollow needle is moved through the opening in the base when the platform is moved into a second position relative to the struts.
124. A method according to claim 123, wherein arranging the first end of the hollow needle comprising attaching the hollow needle to the platform in a position to extend at least partially into a reservoir when the reservoir is supported on the platform and wherein moving the hollow needle comprises moving the hollow needle into the second position in conjunction with the movement of the platform from the first position of the platform to the second position of the platform relative to the struts.
125. A delivery device for delivering an infusion media to a user, the device comprising:
a housing having a base adapted to be secured to a user's skin;
a reservoir for containing infusion media, wherein the reservoir is supported by the housing; and a moveable hollow needle selectively engageable with the reservoir for communication of infusion media from the reservoir, the moveable hollow needle being supported by the housing for movement relative to the base of he housing between a first position and a second position, wherein the moveable hollow needle is spaced apart from a user's skin when the needle is in the first position and the base of the housing is secured to the user's skin, and wherein the moveable hollow needle is arranged to pierce the user's skin when the needle is in the second position and the base of the housing is secured to the user's skin.
a housing having a base adapted to be secured to a user's skin;
a reservoir for containing infusion media, wherein the reservoir is supported by the housing; and a moveable hollow needle selectively engageable with the reservoir for communication of infusion media from the reservoir, the moveable hollow needle being supported by the housing for movement relative to the base of he housing between a first position and a second position, wherein the moveable hollow needle is spaced apart from a user's skin when the needle is in the first position and the base of the housing is secured to the user's skin, and wherein the moveable hollow needle is arranged to pierce the user's skin when the needle is in the second position and the base of the housing is secured to the user's skin.
126. A delivery device according to claim 125 wherein the housing comprises a disposable housing portion and a durable housing portion configured to be selectively engaged with and disengaged from the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion, the base being part of the disposable housing portion and the reservoir being supported by the disposable housing portion.
127. A delivery device according to claim 126, further comprising electrical control circuitry contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
128. A delivery device according to claim 126, further comprising electrical control circuitry and a drive device contained in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user and wherein the drive device operatively couples to the reservoir to drive infusion media from the reservoir under control of the electrical control circuitry when the durable housing portion is engaged with the disposable housing portion.
129. A delivery device according to claim 125, wherein the reservoir comprises a container and a septum, the septum is aligned with a sharp end of the moveable hollow needle for piercing the septum as the moveable hollow needle is moved from the first position to the second position.
130. A delivery device according to claim 125, further comprising:
a spring and latch structure operatively coupled to the moveable hollow needle, for imparting a spring force on the moveable hollow needle in a direction toward the second position and selectively latching the moveable hollow needle in the first position against the spring force; wherein the latch structure comprises a manual operator to selectively unlatch the moveable hollow needle to allow the moveable hollow needle to move to the second position by operation of the spring force.
a spring and latch structure operatively coupled to the moveable hollow needle, for imparting a spring force on the moveable hollow needle in a direction toward the second position and selectively latching the moveable hollow needle in the first position against the spring force; wherein the latch structure comprises a manual operator to selectively unlatch the moveable hollow needle to allow the moveable hollow needle to move to the second position by operation of the spring force.
131. A delivery device according to claim 130, wherein the manual operator comprises at least one pivotal lever pivotal between first and second pivot positions and having an engaging portion for engaging the spring and inhibiting the spring from moving the moveable hollow needle when the moveable hollow needle is in the first position and the pivotal lever is in the first pivot position, and wherein the engaging portion of the pivotal lever is disengaged from the spring to allow the spring to move the moveable hollow needle toward the second position when the pivotal lever is pivoted from the first pivot position to the second pivot position.
132. A delivery device according to claim 131, wherein the at least one pivotal lever comprises a pair of pivotal levers.
133. A delivery device according to claim 131, wherein the spring comprises a coil spring that is compressed when the moveable hollow needle is in the first position and expands to move the moveable hollow needle toward the second position when the pivotal lever is pivoted to disengage the engaging portion of the pivotal lever from the spring.
134. A delivery device according to claim 130, wherein the manual operator comprises a rotatable member having a catch, wherein the rotatable member is supported for rotation between a first catch position and a second catch position, wherein the catch of the rotatable member is located for engaging the spring and inhibiting the spring from moving the moveable hollow needle when the moveable hollow needle is in the first position and the rotatable member is in the first catch position, and wherein the catch of the rotatable member is disengaged from the spring to allow the spring to move the moveable hollow needle toward the second position when the rotatable member is rotated from the first catch position to the second catch position.
135. A delivery device according to claim 134, wherein the spring comprises a coil spring that is compressed when the moveable hollow needle is in the first position and expands to move the moveable hollow needle toward the second position when the rotatable member is rotated to disengage the catch of the rotatable member from the spring.
136. A delivery device according to claim 134, wherein reservoir has an infusion medium flow path in flow communication with the moveable hollow needle when the moveable hollow needle is in the second position and wherein the rotatable member includes a valve extending into the flow path, the valve having a closed state inhibiting infusion medium from flowing from the reservoir to the moveable hollow needle when the rotatable member is in the first catch position and the valve having an open state allowing infusion medium to flow from the reservoir to the moveable hollow needle when the rotatable member is in the second catch position.
137. A delivery device according to claim 136, wherein the hollow needle has a side opening in flow communication with the flow path of the reservoir when the moveable hollow needle is in the second position.
138. A delivery device according to claim 136, wherein the reservoir further includes a septum that is pierced by the moveable hollow needle when the moveable hollow needle moves to the second position and wherein the hollow needle has a side opening that comes into flow communication with the flow path of the reservoir when the moveable hollow needle moves to the second position.
139. A delivery device according to claim 125, wherein the reservoir has an infusion medium flow path in flow communication with the moveable hollow needle when the moveable hollow needle is in the second position and wherein the hollow needle has a side opening in flow communication with the flow path of the reservoir when the moveable hollow needle is in the second position.
140. A delivery device according to claim 125, wherein the reservoir has an infusion medium flow path and a septum that is pierced by the moveable hollow needle when the moveable hollow needle moves to the second position and wherein the hollow needle has a side opening that comes into flow communication with the flow path of the reservoir when the moveable hollow needle moves to the second position.
141. A method for delivering an infusion media to a user, the method comprising:
providing a housing having a base adapted to be secured to a user's skin;
supporting a reservoir by the housing, the reservoir for containing an infusion media; and supporting a moveable hollow needle for selective engagement with the reservoir for communication of infusion media from the reservoir, including supporting the moveable hollow needle for movement relative to the base of he housing between a first position and a second position, wherein the moveable hollow needle is spaced apart from a user's skin when the needle is in the first position and the base of the housing is secured to the user's skin, and wherein the moveable hollow needle is arranged to pierce the user's skin when the needle is in the second position and the base of the housing is secured to the user's skin.
providing a housing having a base adapted to be secured to a user's skin;
supporting a reservoir by the housing, the reservoir for containing an infusion media; and supporting a moveable hollow needle for selective engagement with the reservoir for communication of infusion media from the reservoir, including supporting the moveable hollow needle for movement relative to the base of he housing between a first position and a second position, wherein the moveable hollow needle is spaced apart from a user's skin when the needle is in the first position and the base of the housing is secured to the user's skin, and wherein the moveable hollow needle is arranged to pierce the user's skin when the needle is in the second position and the base of the housing is secured to the user's skin.
142. A method according to claim 141, wherein providing a housing comprises providing a disposable housing portion and a durable housing portion, and selectively engaging and disengaging the durable housing portion with the disposable housing portion to allow disposal of the disposable housing portion without disposing of the durable housing portion, the base being part of the disposable housing portion.
143. A method according to claim 142, further comprising containing electrical control circuitry in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user.
144. A method according to claim 142, further comprising containing electrical control circuitry and a drive device in the durable housing portion, wherein the electrical control circuitry controls the delivery of infusion media from the reservoir to the user; and operatively coupling the drive device to the reservoir to drive infusion media from the reservoir under control of the electrical control circuitry when the durable housing portion is engaged with the disposable housing portion.
145. A method according to claim 141, wherein the reservoir comprises a container and a septum, the method further comprising aligning the septum with a sharp end of the moveable hollow needle for piercing the septum as the moveable hollow needle is moved from the first position to the second position.
146. A method according to claim 141, further comprising:
operatively coupling a spring and latch structure to the moveable hollow needle, for imparting a spring force on the moveable hollow needle in a direction toward the second position and selectively latching the moveable hollow needle in the first position against the spring force;
providing a manual operator for selectively unlatching the moveable hollow needle to allow the moveable hollow needle to move to the second position by operation of the spring force.
operatively coupling a spring and latch structure to the moveable hollow needle, for imparting a spring force on the moveable hollow needle in a direction toward the second position and selectively latching the moveable hollow needle in the first position against the spring force;
providing a manual operator for selectively unlatching the moveable hollow needle to allow the moveable hollow needle to move to the second position by operation of the spring force.
147. A method according to claim 146, wherein providing a manual operator comprises supporting at least one pivotal lever pivotal between first and second pivot positions, providing the pivotal lever with an engaging portion for engaging the spring and inhibiting the spring from moving the moveable hollow needle when the moveable hollow needle is in the first position and the pivotal lever is in the first pivot position, and wherein the engaging portion of the pivotal lever is disengaged from the spring to allow the spring to move the moveable hollow needle toward the second position when the pivotal lever is pivoted from the first pivot position to the second pivot position.
148. A method according to claim 147, wherein supporting at least one pivotal lever comprises supporting a pair of pivotal levers.
149. A method according to claim 146, wherein supporting a reservoir comprises supporting a reservoir having an infusion medium flow path in flow communication with the moveable hollow needle when the moveable hollow needle is in the second position and wherein providing a manual operator comprises providing a rotatable member having a valve extending into the flow path, the valve having a closed state inhibiting infusion medium from flowing from the reservoir to the moveable hollow needle when the rotatable member is in the first catch position and the valve having an open state allowing infusion medium to flow from the reservoir to the moveable hollow needle when the rotatable member is in the second catch position.
150. A method according to claim 149, wherein the hollow needle has a side opening in flow communication with the flow path of the reservoir when the moveable hollow needle is in the second position.
151. A method according to claim 146, wherein supporting a reservoir comprises supporting a container having a septum in a position to be pierced by the moveable hollow needle when the moveable hollow needle moves to the second position and wherein the hollow needle has a side opening that comes into flow communication with the container of the reservoir when the moveable hollow needle moves to the second position.
152. A method according to claim 141, wherein supporting a reservoir comprises supporting a container having a septum in a position to be pierced by the moveable hollow needle when the moveable hollow needle moves to the second position and wherein the hollow needle has a side opening that comes into flow communication with the container of the reservoir when the moveable hollow needle moves to the second position.
153. A needle structure for communicating media to or from a patient, the needle structure comprising a hollow needle having a longitudinal dimension, a passage along at least a portion of its longitudinal dimension for conveying a flowable medium and at least one bend along its longitudinal dimension.
154. A needle structure according to claim 153, wherein the hollow needle has a plurality of bends along its longitudinal dimension.
155. A needle structure according to claim 153, wherein one side of the needle is affixed to a reservoir containing infusion media and the other side of the needle has a sharp end for penetrating the skin of a user.
156. A needle structure according to claim 155, wherein the needle has a plurality of right-angle bends along its longitudinal dimension that dampen movements of the end of the needle that is affixed to the reservoir with respect to the sharp end of the needle.
157. A needle structure according to claim 155, wherein the needle has at least one loop along its longitudinal dimension that dampen movements of the end of the needle that is affixed to the reservoir with respect to the sharp end of the needle.
158. A needle structure according to claim 155, wherein the needle has a plurality of coiled loops along its longitudinal dimension that dampens movements of the end of the needle that is affixed to the reservoir with respect to the sharp end of the needle.
159. A needle structure according to claim 153, wherein the needle has two ends and a plurality of right-angle bends along its longitudinal dimension that dampen movements of one end of the needle with respect to the other end of the needle.
160. A needle structure according to claim 153, wherein the needle has two ends and at least one loop along its longitudinal dimension that dampen movements of one end of the needle with respect to the other end of the needle.
161. A needle structure according to claim 153, wherein the needle has two ends and a plurality of coiled loops along its longitudinal dimension that dampen movement of one end of the needle with respect to the other end of the needle.
162. A needle for selective introduction into a user, comprising a hollow tube having a longitudinal dimension a sharp end and a second end, a passage along at least a portion of its longitudinal dimension for conveying a flowable medium, the hollow tube having at least one nonlinear segment for dampening movements of the second end of the hollow tube relative to the sharp end of the hollow tube.
163. A needle according to claim 162, wherein the at least one nonlinear segment comprises a plurality of bends along a portion of the longitudinal dimension of the hollow tube.
164. A needle according to claim 163, wherein the at least one nonlinear segment comprises a plurality of right-angle bends along a portion of the longitudinal dimension of the hollow tube.
165. A needle according to claim 163, wherein the at least one nonlinear segment comprises a plurality of coiled loops along a portion of the longitudinal dimension of the hollow tube.
166. A needle according to claim 162, wherein the at least one nonlinear segment comprises at least one right angle bend along a portion of the longitudinal dimension of the hollow tube.
167. A needle according to claim 162, wherein the at least one nonlinear segment comprises at least one loop along a portion of the longitudinal dimension of the hollow tube.
168. A delivery device for delivering infusion media to a user, the delivery device comprising a reservoir for containing an infusion media and a needle for selective introduction into a user, wherein the needle comprises a hollow tube having a longitudinal dimension a dispensing end and a second end, a passage along at least a portion of its longitudinal dimension in flow communication with the reservoir for conveying a flowable media from the reservoir toward the dispensing end of the hollow tube, the hollow tube having at least one nonlinear segment for dampening movements of the reservoir or the second end of the hollow tube relative to the dispensing end of the hollow tube.
169. A device according to claim 168, wherein the at least one nonlinear segment of the hollow tube comprises a plurality of bends along a portion of the longitudinal dimension of the hollow tube.
170. A device according to claim 169, wherein the at least one nonlinear segment of the hollow tube comprises a plurality of right-angle bends along a portion of the longitudinal dimension of the hollow tube.
171. A device according to claim 169, wherein the at least one nonlinear segment of the hollow tube comprises a plurality of coiled loops along a portion of the longitudinal dimension of the hollow tube.
172. A device according to claim 168, wherein the at least one nonlinear segment comprises at least one right angle bend along a portion of the longitudinal dimension of the hollow tube.
173. A device according to claim 168, wherein the at least one nonlinear segment comprises at least one loop along a portion of the longitudinal dimension of the hollow tube.
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-
2005
- 2005-08-23 US US11/211,143 patent/US9233203B2/en active Active
- 2005-08-23 US US11/211,157 patent/US7955305B2/en active Active
- 2005-08-23 US US11/211,150 patent/US7699833B2/en active Active
- 2005-08-23 US US11/210,467 patent/US7569050B2/en active Active
- 2005-08-23 US US11/210,455 patent/US7641649B2/en active Active
- 2005-08-23 US US11/211,095 patent/US7686787B2/en active Active
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2006
- 2006-05-05 EP EP10181655A patent/EP2289580A1/en not_active Withdrawn
- 2006-05-05 WO PCT/US2006/017518 patent/WO2006121921A2/en active Application Filing
- 2006-05-05 DK DK06752347.2T patent/DK1893255T3/en active
- 2006-05-05 EP EP06752347.2A patent/EP1893255B1/en active Active
- 2006-05-05 CA CA2602472A patent/CA2602472C/en active Active
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2010
- 2010-01-28 US US12/695,844 patent/US7935085B2/en not_active Expired - Fee Related
- 2010-06-04 US US12/793,991 patent/US9180248B2/en active Active
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EP1893255A2 (en) | 2008-03-05 |
US20160067403A1 (en) | 2016-03-10 |
US20060264889A1 (en) | 2006-11-23 |
US20060264894A1 (en) | 2006-11-23 |
US9180248B2 (en) | 2015-11-10 |
US9233203B2 (en) | 2016-01-12 |
US20060253086A1 (en) | 2006-11-09 |
US10220143B2 (en) | 2019-03-05 |
WO2006121921A2 (en) | 2006-11-16 |
US20190143039A1 (en) | 2019-05-16 |
US7641649B2 (en) | 2010-01-05 |
WO2006121921A8 (en) | 2006-12-21 |
US7569050B2 (en) | 2009-08-04 |
US7935085B2 (en) | 2011-05-03 |
EP1893255B1 (en) | 2015-10-28 |
EP2289580A1 (en) | 2011-03-02 |
US20080009824A1 (en) | 2008-01-10 |
US20060264890A1 (en) | 2006-11-23 |
CA2602472C (en) | 2010-08-03 |
DK1893255T3 (en) | 2016-02-08 |
US20100241065A1 (en) | 2010-09-23 |
US20100130943A1 (en) | 2010-05-27 |
US7699833B2 (en) | 2010-04-20 |
US11141530B2 (en) | 2021-10-12 |
US7955305B2 (en) | 2011-06-07 |
US7686787B2 (en) | 2010-03-30 |
US20060264888A1 (en) | 2006-11-23 |
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