CA2864697A1 - Hammer toe implant and method - Google Patents

Hammer toe implant and method Download PDF

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Publication number
CA2864697A1
CA2864697A1 CA 2864697 CA2864697A CA2864697A1 CA 2864697 A1 CA2864697 A1 CA 2864697A1 CA 2864697 CA2864697 CA 2864697 CA 2864697 A CA2864697 A CA 2864697A CA 2864697 A1 CA2864697 A1 CA 2864697A1
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Prior art keywords
bone
implant
surgical device
threaded portion
longitudinal axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2864697
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French (fr)
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CA2864697C (en
Inventor
Daniel Francis Mccormick
Jessica Lauren Shemwell
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Wright Medical Technology Inc
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Wright Medical Technology Inc
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Publication date
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Publication of CA2864697A1 publication Critical patent/CA2864697A1/en
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Publication of CA2864697C publication Critical patent/CA2864697C/en
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary pins, nails or other devices
    • A61B17/7291—Intramedullary pins, nails or other devices for small bones, e.g. in the foot, ankle, hand or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/42—Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/42—Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4225—Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for feet, e.g. toes

Abstract

An implant includes an elongate threaded portion defining a first central longitudinal axis and a groove. The groove defines a second longitudinal central axis that extends in the same direction as the first central longitudinal axis. A blade portion extends from the elongate threaded portion and has a taper terminating at a point.

Description

PATENT
E3383-00349 (713.008) HAMMER TOE IMPLANT AND METHOD
FIELD OF DISCLOSURE
[0001] The disclosed system and method relate implants. More specifically, the disclosed system and method relate to installing an implant for treating hammer toe.
BACKGROUND
[0002] Hammer toe is a deformity of the toe that affects the alignment of the bones adjacent to the proximal interphalangeal (PIP) joint. Hammer toe can cause pain and can lead to difficulty in walking or wearing shoes. A hammer toe can often result in an open sore or wound on the foot. In some instances, surgery may be required to correct the deformity by fusing one or both of the PIP and distal interphalangeal (DIP) joints. Improved implants and surgical devices are desirable.
SUMMARY
[0003] In some embodiments, an implant includes an elongate threaded portion defining a first central longitudinal axis and a groove. The groove defines a second longitudinal central axis that extends in the same direction as the first central longitudinal axis. A blade portion extends from the elongate threaded portion and has a taper terminating at a point.
[0004] In some embodiments, a method includes forming an incision to gain access to a joint between first and second bones, flexing the first and second bones such that the first and second bones are disposed at an angle with respect to one another, and inserting a surgical device into a first end of the first bone until a trailing end of the surgical device is disposed adjacent to the first end of the first bone. A slot is formed in the first end of the first bone adjacent to a location at which the surgical device is received within the first bone, and a threaded portion of an implant is advanced into a first end of the second bone. The first bone is repositioned such that the slot formed in the first bone aligns with a blade portion of the implant that extends from the first end of the second bone. The first bone is forced into engagement with the blade portion of the implant, and the first surgical device is advanced across the joint and into engagement with a groove defined by the threaded portion of the implant.

DM2 4451819.1 PATENT
E3383-00349 (713.008) [0005] A method includes inserting a leading end of a surgical device into an exposed first end of a first bone until a trailing end of the surgical device is disposed adjacent to the first end of the first bone. A threaded portion of an implant is advanced into an exposed first end of a second bone, and the first bone is repositioned such that a slot formed in the first bone adjacent to the surgical device aligns with a blade portion of the implant that extends from the first end of the second bone. The first bone is forced into engagement with a blade portion of the implant, and the trailing end of the surgical device is advanced across a joint between the first and second bones and into a groove defined by the threaded portion of the implant.
BRIEF DESCRIPTION OF THE DRAWINGS
[0006] These and other features and advantages of the present invention will be more fully disclosed in, or rendered obvious by the following detailed description of preferred embodiments, which are to be considered together with the accompanying drawings wherein like numbers refer to like parts and further wherein:
[0007] FIG. 1 is an isometric view of one example of an improved hammer toe implant in accordance with some embodiments;
[0008] FIG. 2 is another isometric view of the hammer toe implant illustrated in FIG. 1 in accordance with some embodiments;
[0009] FIG. 3 is a side view of the hammer toe implant illustrated in FIG.
1 in accordance with some embodiments;
[0010] FIG. 4 is an end on view of the hammer toe implant illustrated in FIG. 1 in accordance with some embodiments;
[0011] FIG. 5 is a sectional view of the hammer toe implant illustrated in FIG. 1 taken along line 5-5 in FIG. 4 in accordance with some embodiments.;
[0012] FIG. 6 is an isometric view of the hammer toe implant illustrated in FIG. 1 coupled to a surgical device in accordance with some embodiments;
[0013] FIG. 7 is an end view of the hammer toe implant illustrated in FIG.
1 coupled to a surgical device in accordance with some embodiments;
[0014] FIG. 8 is a cross-sectional view taken along line 8-8 in FIG. 7 of the hammer toe implant illustrated in FIG. 1 coupled to a surgical device in accordance with some embodiments;

PATENT
E3383-00349 (713.008) [0015] FIG. 9 illustrates one example of an incision being made to gain access to a joint between at least two bones in accordance with some embodiments.
[0016] FIG. 10 illustrates one example of a cutting blade being used to resect faces of adjacent bones of a joint in accordance with some embodiments.
[0017] FIG. 11 illustrates a surgical device being inserted into a bone adjacent to a broach or drill site in accordance with some embodiments;
[0018] FIG. 12 illustrates one example of an implant being driven into a bone using a driving tool in accordance with some embodiments.
[0019] FIG. 13 illustrates an implant in accordance with FIG. 1 having been inserted into a bone disposed adjacent to the bone in which a surgical device is inserted in accordance with some embodiments;
[0020] FIG. 14 illustrates the surgical device being advanced into bones and engaging a portion of the implant in accordance with some embodiments; and [0021] FIG. 15 illustrates the surgical device being removed from bone and its engagement with the implant in accordance with some embodiments.
DETAILED DESCRIPTION
[0022] This description of preferred embodiments is intended to be read in connection with the accompanying drawings, which are to be considered part of the entire written description. The drawing figures are not necessarily to scale and certain features of the invention may be shown exaggerated in scale or in somewhat schematic form in the interest of clarity and conciseness. In the description, relative terms such as "horizontal,"
"vertical," "up," "down,"
"top," and "bottom" as well as derivatives thereof (e.g., "horizontally,"
"downwardly,"
"upwardly," etc.) should be construed to refer to the orientation as then described or as shown in the drawing figure under discussion. These relative terms are for convenience of description and normally are not intended to require a particular orientation. Terms including "inwardly" versus "outwardly," "longitudinal" versus "lateral," and the like are to be interpreted relative to one another or relative to an axis of elongation, or an axis or center of rotation, as appropriate.
Terms concerning attachments, coupling, and the like, such as "connected" and "interconnected,"
refer to a relationship wherein structures are secured or attached to one another either directly or indirectly through intervening structures, as well as both movable or rigid attachments or DM2 \4453819 1 PATENT
E3383-00349 (713.008) relationships, unless expressly described otherwise. The term "operatively connected" is such an attachment, coupling or connection that allows the pertinent structures to operate as intended by virtue of that relationship.
[0023] The disclosed implant, systems, and methods advantageously enable an implant to be installed through a small incision while stabilizing a joint, such as a metatarsophalangeal joint. Additionally, the implant is capable of being completely disposed within a toe of a patient, which prevents the implant from being caught on bed sheets or other objects like the conventional pins when installed for treating a joint condition.
[0024] FIGS. 1-8 illustrate one example of an improved implant 100 for treating hammer toe in accordance with some embodiments. As best seen in FIGS. 1 and 2, implant 100 includes a threaded portion 102 and a blade portion 104, which are connected together at an engagement portion 106. Implant 100 may have a substantially linear geometry, such that a longitudinal axis defined by blade portion 104 is aligned or collinear with a longitudinal axis defined by threaded portion 102, and have an overall length of approximately 19 mm (approximately 0.75 inches).
However, in some embodiments, blade portion 104 is disposed at angle with respect to a longitudinal axis defined by the threaded portion 102 such that a longitudinal axis defined by the blade portion 104 is not aligned nor collinear with a longitudinal axis defined by threaded portion 102. For example, in some embodiments, the angle is between zero and 45 degrees, and more particularly between approximately five and fifteen degrees. Commonly assigned U.S.
Patent Application No. 13/086,136, filed April 13, 2011 and which is incorporated by reference herein in its entirety, discloses one example of an implant having an angled (e.g., non-linear) configuration. One of ordinary skill in the art will understand that implant 100 may have other dimensions and be provided in different sizes. For example, implant 100 may be provided in lengths of 16 mm and 22 mm, to identify only a few potential lengths.
[0025] Threaded portion 102 includes a plurality of threads 108 disposed along its entire length. In some embodiments, the length of threaded portion 102 is approximately 13 mm (approximately 0.5 inches). Threaded portion 102 tapers to a pointed tip 110 to facilitate the advancement of threads 108 into bone. In some embodiments, threads 108 have a maximum outer diameter of approximately 2 mm (approximately 0.08 inches), although one skilled in the art will understand that thread portion 102 may have other dimensions and be configured to be received within a phalanx bone of a person. For example, in some embodiments, threads 108 DM2 \4453819.1 PATENT
E3383-00349 (713.008) have an outer diameter of between approximately 1.6 mm and 4 mm, such as, for example, 1.6 mm, 2.4 mm, 3.2 mm, and 4.0 mm, to identify only a few potential possibilities.
[0026] Threaded portion 102 includes a groove 109 sized and configured to receive a k-wire, pin, or other surgical device or instrument therein as described in greater detail below.
Groove 109 extend along the length of threaded portion 102 in a direction that is parallel to a longitudinal length defined by threaded portion 102. In some embodiments, as best seen in FIGS. 1 and 2, a central axis of groove 109 is disposed adjacent to a central longitudinal axis defined by threaded portion 102. Put another way, the central axis defined by groove 109 is not collinear with, and is parallel to, the central axis defined by threaded portion 102, which extends through the center of threaded portion 102 and blade portion 104. In some embodiments, groove 109 is disposed such that it is tangent to a minor diameter of threads 108.
Although not shown, in some embodiments groove 109 is collinear with the central axis defined by threaded portion 102 (and blade portion 104). FIGS. 6 and 7 show a k-wire 10 disposed within groove 109. In some embodiments, such as the embodiment illustrated in FIG. 7, a gap G is provided between k-wire 10 and a side 128 of blade portion 104, which is disposed opposite of side 130 of blade portion 104 as shown in FIGS. 4 and 8. Gap G enables bone to be received between surgical device 10 and blade portion 106.
[0027] As best seen in FIG. 1, blade portion 104 includes a plurality of serrated edges 112 on first side 114 and on a second side 116. Serrated edges 112 each have a thickness that is approximately equal to the thickness of blade portion 104. Put another way, in some embodiments, blade portion 104 does not taper along its thickness direction as best seen in FIG.
3. Serrated edges are separated from one another by valleys or indentations 126 shown in FIGS.
1 and 3. Blade portion 104 may have a width that is greater than its thickness as best seen in FIGS. 1 and 2. For example, blade portion 104 may have a width of approximately 0.4 centimeters (approximately 0.16 inches) and a thickness of approximately 0.1 centimeters (approximately 0.04 inches) each of which taper to point 118 at the distal-most end of blade portion 104. In some embodiments, blade portion 104 has a substantially rectangular cross-sectional area as illustrated in FIG. 4, although one skilled in the art will understand that blade portion 104 may have other cross-sectional geometries.
[0028] Engagement portion 106 includes a pair of protrusions 120 extending from opposite sides of implant 100 and having rounded outer edges 122 as best seen in FIGS. 1 and 2.
DM2\4453819 1 PATENT
E3383-00349 (713.008) The sides 124 of protrusions 120 may be substantially parallel with each other as shown in FIG.
5. Protrusions extend away from one another in a direction that is perpendicular with respect to a longitudinal direction of implant 100.
[0029] A method of installing implant 100 in a joint between at least two bones is described with reference to FIGS. 9-15. Although the method is described as installing an implant in the bones of a proximal interphelangeal joint (PIP) 200, i.e., the joint between proximal phalange 202 and middle phalange 304, one of ordinary skill in the art will understand that the technique for installing the implant 100 may be applied to other joints, such as, for example, the distal interphelangeal (DIP) joint, i.e., joint 208 between middle phalange 304 and distal phalange 206. As shown in FIG. 9, an incision is made to open the PIP
joint 200. In some embodiments, a cutting tool 300 having a blade 302 is used to resect adjacent faces of proximal phalanx 202 and middle phalanx 204 as shown in FIG. 10. The resected surfaces of proximal phalanx 202 and middle phalanx 204 may be debrided as understood by one of ordinary skill in the art.
[0030] A k-wire, pin, or other suitable surgical device 10 is inserted into the middle phalange 204 and driven through distal phalange 206 and out the end of the toe as shown in FIG.
11. In some embodiments, middle phalange 204 is broached or pre-drilled to create an opening 210 also shown in FIG. 11, and a pilot hole 212 is formed in proximal phalange 202 using a drill, broach, or other suitable surgical device (not shown). The hole 210 created by the broach is located at a distance from the k-wire 10 that corresponds to the distance of gap G.
[0031] K-wire 10 is inserted such that trailing end 10B (not shown in FIG.
11) is disposed within middle phalange 204 or otherwise positioned with respect to joint 200 such that implant 100 can be driven into proximal phalange 202. In some embodiments, threaded portion 102 of implant 100 is driven into proximal phalange 202 using a driving tool.
For example, FIG.
12 illustrates implant 100 being driven into middle phalange 204 using a driving tool 400, such as a driving tool disclosed in commonly assigned U.S. Patent Application No.
13/086,136, which is incorporated by reference herein in its entirety. One of ordinary skill in the art will understand that other driving tools can be used. Shaft 402 of driving tool 400 can be engaged with a chuck of a drill (not shown) to advance threaded portion 102 of implant 100 into pilot hole 212.
Implant 100 is driven into bone until engagement portion abuts bone. Implant 100 is decoupled DM2 \ 4453819.1 PATENT
E3383-00349 (713.008) from driving tool 400 by axially pulling handle (not shown) away from implant 100 with sufficient force to flex o-ring 404 and separate driving tool 400 from implant 100.
[0032] FIG. 13 illustrates threaded portion 102 of implant 100 disposed within a first bone, such as proximal phalange 202, and end 10B of surgical device 10 disposed within a second bone, such as middle phalange 204. Blade portion 104 is exposed as it extends from the distal end of middle phalange 202.
[0033] The middle phalange 204 is repositioned such that hole 210 formed by broaching the middle phalange 204 aligns with the blade portion 104 of implant 100, which extends from the end of proximal phalange 202. Additionally, k-wire 10 disposed within middle phalange 204 aligns with the groove 109 defined by blade portion 104 of implant 100, which is disposed within proximal phalange 202. Middle phalange 204 is pressed into engagement with the blade portion 104 as shown in FIG. 14. Serrated edges 112 of blade portion 104 help to maintain the engagement between middle phalanx 204 and blade portion 104 of implant 100.
[0034] In some embodiments, k-wire 10 is advanced across joint 200, into and through middle phalange 202, and into metatarsal 214 through implant 100 as shown in FIG. 14. The k-wire 10 is received within groove 109 such that implant 100 engages surgical device 10. What was initially leading end 10A (FIGS. 11 and 13), can be blunted or capped to provide an exposed blunt end 10C shown in FIG. 14. The surgical device 10 can remain within a patient for a period of time, e.g., minutes, hours, days, or months, and then be removed as shown in FIG. 15 to leave behind implant 100.
[0035] Thus, in some embodiments a surgical method includes forming an incision to gain access to a joint between the first bone and the second bone, resecting at least one of the first end of the first bone and the first and of the second bone, and flexing the first bone relative to the second bone to expose the first end of the first bone and the first end of the second bone.
A first surgical device is inserted into the first bone until a trailing end of the first surgical device disposed adjacent to a first end of the first bone. The first end of the first bone is broached at a location that is adjacent to a location at which the first surgical device is disposed in the first bone. A pilot hole is formed in the first end of the second bone, and a threaded portion of an implant is advanced into the pilot hole formed in the second bone. The first bone is repositioned such that the hole formed in the first end of the first bone by the broach is aligned with a blade portion of the implant extending from the first end of the second bone. The first bone is forced PATENT
E3383-00349 (713.008) into engagement with the blade portion of the implant. The first surgical device is advanced across the joint, into the second bone such that first surgical device is received within a groove defined by the threaded portion of the implant. The first surgical device is further advanced across a second joint into a third bone. After a period of time, the first surgical device is removed from its engagement with the implant and the first, second, and third bones while the implant remains disposed within the first and second bones.
[0036] The implant described above may advantageously be installed through a small incision as described above. Further, the inclusion of a groove in the implant that is sized and configured to receive a k-wire enables the implant to be installed while the joint is stabilized.
[0037] Although the disclosed implant, system, and method have been described in terms of exemplary embodiments, they are not limited thereto. Rather, the appended claims should be construed broadly, to include other variants and embodiments of the system, implant, and method, which may be made by those skilled in the art without departing from the scope and range of equivalents of the implant, system, and method.

DM24453819.1

Claims (19)

What is claimed is:
1. An implant, comprising:
an elongate threaded portion defining a first central longitudinal axis and a groove, the groove defining a second longitudinal central axis that extends in the same direction as the first central longitudinal axis; and a blade portion extending from the elongate threaded portion, the blade portion having a taper terminating at a point.
2. The implant of claim 1, wherein the blade portion includes a plurality of serrated edges.
3. The implant of claim 1, wherein the blade portion tapers along its width and thickness to the point.
4. The implant of claim 1, further comprising an engagement portion disposed between the threaded portion and the blade portion, the engagement portion including a pair of projections extending in opposite directions away from each other in a direction that is perpendicular to the first central longitudinal axis defined by the threaded portion.
5. The implant of claim 1, wherein the second central longitudinal axis is disposed parallel to, but not collinear with, the first central longitudinal axis.
6. The implant of claim 5, wherein the groove defined by the threaded portion is tangent to a minor diameter of the threads of the threaded portion.
7. A method, comprising:
forming an incision to gain access to a joint between first and second bones;
flexing the first and second bones such that the first and second bones are disposed at an angle with respect to one another;
inserting a surgical device into a first end of the first bone until a trailing end of the surgical device is disposed adjacent to the first end of the first bone;

forming a slot in the first end of the first bone adjacent to a location at which the surgical device is received within the first bone;
advancing a threaded portion of an implant into a first end of the second bone;
repositioning the first bone such that the slot formed in the first bone aligns with a blade portion of the implant that extends from the first end of the second bone;
forcing the first bone into engagement with the blade portion of the implant;
and advancing the first surgical device across the joint and into engagement with a groove defined by the threaded portion of the implant.
8. The method of claim 7, further comprising removing the surgical device from the first and second bones and its engagement with the implant.
9. The method of claim 7, further comprising resecting at least one of the first end of the first and second bones prior to inserting the surgical device.
10. The method of claim 7, wherein the first bone is one of a proximal phalanx or a middle phalanx of a foot, and the second bone is the other of the proximal phalanx or the middle phalanx of a foot.
11. The method of claim 10, wherein the surgical device is further advanced across a second joint and into a metatarsal bone.
12. The method of claim 7, wherein the threaded portion of the implant defines a first central longitudinal axis that is disposed parallel to, but not collinear with, a second central longitudinal axis defined by the groove.
13. The method of claim 7, further comprising forming a pilot hole in the first end of the second bone prior to advancing the threaded portion of the implant into the first end of the second bone.
14. A method, comprising:

inserting a leading end of a surgical device into an exposed first end of a first bone until a trailing end of the surgical device is disposed adjacent to the first end of the first bone;
advancing a threaded portion of an implant into an exposed first end of a second bone;
repositioning the first bone such that a slot formed in the first bone adjacent to the surgical device aligns with a blade portion of the implant that extends from the first end of the second bone;
forcing the first bone into engagement with a blade portion of the implant;
and advancing the trailing end of the surgical device across a joint between the first and second bones and into a groove defined by the threaded portion of the implant.
15. The method of claim 14, further comprising forming an incision to gain access to the joint between the first bone and the second bone;
flexing the first bone relative to the second bone to expose the first end of the first bone and the first end of the second bone; and resecting at least one of the first end of the first bone and the first and of the second bone.
16. The method of claim 15, further comprising forming a pilot hole in the first end of the second bone prior to advancing the threaded portion of the implant into the first end of the second bone.
17. The method of claim 15, further comprising advancing the surgical device across a second joint between the second bone and a third bone and into the third bone.
18. The method of claim 17, further comprising removing the surgical device from the first, second, and third bones and its engagement with the groove defined by the implant.
19. The method of claim 14, wherein the threaded portion of the implant defines a first central longitudinal axis that is disposed parallel to, but not collinear with, a second central longitudinal axis defined by the groove.
CA2864697A 2013-10-01 2014-09-25 Hammer toe implant and method Expired - Fee Related CA2864697C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/043,105 US9724139B2 (en) 2013-10-01 2013-10-01 Hammer toe implant and method
US14/043,105 2013-10-01

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CA2864697C CA2864697C (en) 2017-03-07

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US (1) US9724139B2 (en)
EP (1) EP2856957B1 (en)
JP (1) JP2015071038A (en)
KR (1) KR20150039111A (en)
CN (1) CN104510519A (en)
AU (1) AU2014224121B2 (en)
BR (1) BR102014023669A2 (en)
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CA2864697C (en) 2017-03-07
AU2014224121A1 (en) 2015-04-16
KR20150039111A (en) 2015-04-09
EP2856957A1 (en) 2015-04-08
AU2014224121B2 (en) 2017-08-03
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US9724139B2 (en) 2017-08-08
US20150094778A1 (en) 2015-04-02

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