CA960670A - Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof - Google Patents

Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof

Info

Publication number
CA960670A
CA960670A CA073,559A CA73559A CA960670A CA 960670 A CA960670 A CA 960670A CA 73559 A CA73559 A CA 73559A CA 960670 A CA960670 A CA 960670A
Authority
CA
Canada
Prior art keywords
phenoxy
alkyl
preparation
carboxylic acid
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA073,559A
Other versions
CA73559S (en
Inventor
Andre Mieville
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchimed SA
Original Assignee
Orchimed SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH151769A external-priority patent/CH515873A/en
Application filed by Orchimed SA filed Critical Orchimed SA
Application granted granted Critical
Publication of CA960670A publication Critical patent/CA960670A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C8/00—Solid state diffusion of only non-metal elements into metallic material surfaces; Chemical surface treatment of metallic material by reaction of the surface with a reactive gas, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals
    • C23C8/06—Solid state diffusion of only non-metal elements into metallic material surfaces; Chemical surface treatment of metallic material by reaction of the surface with a reactive gas, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using gases
    • C23C8/08—Solid state diffusion of only non-metal elements into metallic material surfaces; Chemical surface treatment of metallic material by reaction of the surface with a reactive gas, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using gases only one element being applied
    • C23C8/10—Oxidising
    • C23C8/12—Oxidising using elemental oxygen or ozone
    • C23C8/14—Oxidising of ferrous surfaces
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C8/00—Solid state diffusion of only non-metal elements into metallic material surfaces; Chemical surface treatment of metallic material by reaction of the surface with a reactive gas, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals
    • C23C8/80—After-treatment
CA073,559A 1969-01-31 1970-01-30 Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof Expired CA960670A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH151769A CH515873A (en) 1969-01-31 1969-01-31 Phenoxyacetic acid derivs
CH1302269A CH543472A (en) 1969-01-31 1969-08-28 Process for the preparation of phenoxyalkylcarboxylic acids

Publications (1)

Publication Number Publication Date
CA960670A true CA960670A (en) 1975-01-07

Family

ID=25687872

Family Applications (1)

Application Number Title Priority Date Filing Date
CA073,559A Expired CA960670A (en) 1969-01-31 1970-01-30 Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof

Country Status (10)

Country Link
US (1) US3914286A (en)
JP (2) JPS5023B1 (en)
BE (1) BE742484A (en)
CA (1) CA960670A (en)
CH (1) CH543472A (en)
ES (1) ES376051A1 (en)
FR (1) FR2035821B1 (en)
GB (1) GB1268321A (en)
NL (1) NL7001424A (en)
SE (2) SE385872B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037529B2 (en) 1997-01-17 2006-05-02 Laboratoires Fournier Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058552A (en) * 1969-01-31 1977-11-15 Orchimed Sa Esters of p-carbonylphenoxy-isobutyric acids
US4233298A (en) * 1969-01-31 1980-11-11 Orchimed Sa Esters of p-carbonylphenoxy-isobutyric acids
US4013719A (en) * 1972-11-01 1977-03-22 Ciba-Geigy Corporation Adamantyl phenoxy alkylamides
US4042711A (en) * 1975-01-09 1977-08-16 Boehringer Ingelheim Gmbh Derivatives of biphenyloxy-lower alkanoic acids, salts thereof and their use as antihyperlipidemics
AT341512B (en) * 1975-01-09 1978-02-10 Thomae Gmbh Dr K METHOD OF MANUFACTURING NEW BIPHENYLATHERS
US4058559A (en) * 1975-09-24 1977-11-15 Abbott Laboratories 4-Aroyl-substituted phenoxy acetic acids
GB1559977A (en) * 1975-11-25 1980-01-30 Ici Ltd Amines
GB1548777A (en) * 1976-12-27 1979-07-18 Kaken Chemical Co Benzoyl phenoxy acetic acid derivatives
JPS53136830U (en) * 1977-04-05 1978-10-28
GB2024209B (en) * 1978-05-31 1982-09-08 Sori Soc Rech Ind Phenoxalkylcarboxylic acids
US4242358A (en) * 1979-01-24 1980-12-30 Societe De Recherches Industrielles (Sori) Method of treatment of algiae
KR850000073B1 (en) * 1979-06-29 1985-02-18 더 웰컴 파운데이숀 리미티드 Process for the preparation of 5-(2-formyl-3-hydroxy phenoxy)pentanoic acid
HU190371B (en) * 1980-12-18 1986-08-28 The Wellcome Foundation Ltd,Gb Process for producing ether-type compounds and pharmaceutical compositions containing them as active agents
DE3512179A1 (en) * 1985-04-03 1986-12-04 Merck Patent Gmbh, 6100 Darmstadt PHOTO INITIATORS FOR PHOTOPOLYMERIZATION IN AQUEOUS SYSTEMS
US5036157A (en) * 1986-03-11 1991-07-30 Burroughs Wellcome Co. Aryl derivatives
US4853404A (en) * 1986-10-13 1989-08-01 Tanabe Seiyaku Co., Ltd. Phenoxyacetic acid derivatives composition and use
US4983567A (en) * 1987-03-16 1991-01-08 Biomeasure, Inc. Immunomodulators and methods of making same
US6063815A (en) * 1998-05-12 2000-05-16 American Home Products Corporation Benzopenones useful in the treatment of insulin resistance and hyperglycemia
FR2795961B1 (en) * 1999-07-09 2004-05-28 Ethypharm Lab Prod Ethiques PHARMACEUTICAL COMPOSITION CONTAINING MICRONIZED FENOFIBRATE, A SURFACTANT AND A BINDING CELLULOSIC DERIVATIVE AND PREPARATION METHOD
US7863331B2 (en) 1999-07-09 2011-01-04 Ethypharm Pharmaceutical composition containing fenofibrate and method for the preparation thereof
JP3386052B2 (en) * 2001-02-13 2003-03-10 トヨタ自動車株式会社 Pump device
MXPA05005736A (en) * 2002-12-17 2005-08-16 Abbott Gmbh & Co Kg Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof.
US7259186B2 (en) * 2002-12-17 2007-08-21 Abbott Laboratories Salts of fenofibric acid and pharmaceutical formulations thereof
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
KR100532103B1 (en) * 2003-05-27 2005-11-29 삼성전자주식회사 Lightfast additives having UV-absorbing moieties and ink composition containing the same
AU2006205099A1 (en) * 2005-01-13 2006-07-20 Wyeth Processes for the preparation of aminoethoxybenzyl alcohols
US20080152714A1 (en) * 2005-04-08 2008-06-26 Yi Gao Pharmaceutical Formulations
CN110615734B (en) * 2018-06-20 2022-03-04 福建博诺安科医药科技有限公司 Industrialized synthesis method of o-aldehyde phenyl fatty acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3383411A (en) * 1964-02-17 1968-05-14 Merck & Co Inc 4-alkanoylphenoxy-alkanoic acids
US3378582A (en) * 1964-03-20 1968-04-16 Merck & Co Inc (alpha-phenoxy)-and (alpha-phenylthio)-omegaphenyl-alkanoic acids
US3379755A (en) * 1964-06-04 1968-04-23 Merck & Co Inc Preparation of (4-alkanoylphenoxy) acetic acids by oxidation
BE674556A (en) * 1965-01-05 1966-06-30
US3704314A (en) * 1968-11-25 1972-11-28 Merck & Co Inc (1-oxo-2-alkylideneindanyloxy) and (1-oxo - 2 - alkylideneindanylthio) alkanoic acids

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037529B2 (en) 1997-01-17 2006-05-02 Laboratoires Fournier Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it
US7041319B2 (en) 1997-01-17 2006-05-09 Laboratoires Fournier Fenofibrate pharmaceutical composition having high bioavailabilty
US8329214B2 (en) 1997-01-17 2012-12-11 Laboratoires Fournier S.A. Process for producing fenofibrate tablets
US8343540B2 (en) 1997-01-17 2013-01-01 Laboratories Fournier S.A. Process for producing fenofibrate tablets

Also Published As

Publication number Publication date
CH543472A (en) 1973-10-31
SE7504490L (en) 1975-04-18
GB1268321A (en) 1972-03-29
US3914286A (en) 1975-10-21
JPS519745B1 (en) 1976-03-30
ES376051A1 (en) 1972-05-16
FR2035821A1 (en) 1970-12-24
BE742484A (en) 1970-05-14
SE385872B (en) 1976-07-26
SE414497B (en) 1980-08-04
NL7001424A (en) 1970-08-04
JPS5023B1 (en) 1975-01-06
FR2035821B1 (en) 1974-08-09

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