CN100506230C - 血管内膜增厚抑制剂 - Google Patents
血管内膜增厚抑制剂 Download PDFInfo
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- CN100506230C CN100506230C CNB2005800017340A CN200580001734A CN100506230C CN 100506230 C CN100506230 C CN 100506230C CN B2005800017340 A CNB2005800017340 A CN B2005800017340A CN 200580001734 A CN200580001734 A CN 200580001734A CN 100506230 C CN100506230 C CN 100506230C
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- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 229940082004 sodium laurate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940075554 sorbate Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
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- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- 239000011975 tartaric acid Substances 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
Description
Claims (5)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004032551 | 2004-02-09 | ||
JP032551/2004 | 2004-02-09 |
Publications (2)
Publication Number | Publication Date |
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CN1905882A CN1905882A (zh) | 2007-01-31 |
CN100506230C true CN100506230C (zh) | 2009-07-01 |
Family
ID=34836093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CNB2005800017340A Expired - Fee Related CN100506230C (zh) | 2004-02-09 | 2005-02-02 | 血管内膜增厚抑制剂 |
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US (2) | US20070161642A1 (zh) |
EP (1) | EP1714654A4 (zh) |
JP (1) | JP4783152B2 (zh) |
KR (1) | KR20070029133A (zh) |
CN (1) | CN100506230C (zh) |
AU (1) | AU2005210326B2 (zh) |
BR (1) | BRPI0507518A8 (zh) |
CA (1) | CA2553915C (zh) |
HK (1) | HK1098377A1 (zh) |
IL (1) | IL176795A (zh) |
RU (1) | RU2339381C2 (zh) |
TW (1) | TWI357409B (zh) |
WO (1) | WO2005074938A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7723362B2 (en) * | 2004-01-08 | 2010-05-25 | Syngenta Crop Protection, Inc. | Pesticidal heterocyclic dihaloallyl compounds |
EP1604988A1 (en) * | 2004-05-18 | 2005-12-14 | Sanofi-Aventis Deutschland GmbH | Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals |
US8314087B2 (en) * | 2007-02-16 | 2012-11-20 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and methods of use |
FR2948939B1 (fr) * | 2009-08-05 | 2013-03-22 | Pf Medicament | Derives de 2h pyridazin-3-ones, leur preparation et leur application en therapeutique humaine |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5202323A (en) * | 1990-04-25 | 1993-04-13 | Nissan Chemical Industries Ltd. | 5-arylmethylamino-6-oxy-substituted 3(2h)-pyridazinones |
PT742211E (pt) * | 1994-01-25 | 2000-10-31 | Nissan Chemical Ind Ltd | Derivados de piridazinona |
JP3666042B2 (ja) * | 1994-01-25 | 2005-06-29 | 日産化学工業株式会社 | ピリダジノン誘導体 |
TW338037B (en) * | 1995-10-05 | 1998-08-11 | Otsuka Pharma Co Ltd | Carbostyril derivatives possessing platelet aggregation inhibitory activity, antithrombotic activity, intima thinkening, inhibitory activity and phosphoriesterase inhibitory activity, their preparation and pharmaceutical composition |
JP2964029B2 (ja) * | 1995-10-05 | 1999-10-18 | 大塚製薬株式会社 | カルボスチリル誘導体 |
KR100559192B1 (ko) * | 1997-08-28 | 2006-03-13 | 닛산 가가쿠 고교 가부시키 가이샤 | 혈관신생 촉진제 및 혈관신생 작용증강제 |
CA2342198C (en) * | 1998-09-01 | 2007-08-28 | Welfide Corporation | Therapeutic agent for spinal canal stenosis |
RU2229885C2 (ru) * | 1998-12-07 | 2004-06-10 | Ниссан Кемикал Индастриз, Лтд. | Средство для лечения нарушения функции эрекции |
JP2001131088A (ja) * | 1999-11-02 | 2001-05-15 | Kyurin:Kk | シンドロームx症候群治療剤 |
CA2304906A1 (en) * | 2000-04-07 | 2001-10-07 | 1411198 Ontario Limited | 13-hode, a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia |
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2005
- 2005-02-02 RU RU2006132389/15A patent/RU2339381C2/ru not_active IP Right Cessation
- 2005-02-02 AU AU2005210326A patent/AU2005210326B2/en not_active Ceased
- 2005-02-02 KR KR1020067014583A patent/KR20070029133A/ko not_active Application Discontinuation
- 2005-02-02 WO PCT/JP2005/001518 patent/WO2005074938A1/ja active Application Filing
- 2005-02-02 BR BRPI0507518A patent/BRPI0507518A8/pt active Search and Examination
- 2005-02-02 CN CNB2005800017340A patent/CN100506230C/zh not_active Expired - Fee Related
- 2005-02-02 EP EP05709638A patent/EP1714654A4/en not_active Withdrawn
- 2005-02-02 CA CA2553915A patent/CA2553915C/en not_active Expired - Fee Related
- 2005-02-02 US US10/585,949 patent/US20070161642A1/en not_active Abandoned
- 2005-02-02 JP JP2005517709A patent/JP4783152B2/ja not_active Expired - Fee Related
- 2005-02-03 TW TW094103407A patent/TWI357409B/zh not_active IP Right Cessation
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2006
- 2006-07-11 IL IL176795A patent/IL176795A/en not_active IP Right Cessation
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2007
- 2007-05-09 HK HK07104940.6A patent/HK1098377A1/xx not_active IP Right Cessation
-
2009
- 2009-01-14 US US12/353,646 patent/US20090155187A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL176795A (en) | 2013-01-31 |
US20090155187A1 (en) | 2009-06-18 |
EP1714654A4 (en) | 2011-02-16 |
EP1714654A1 (en) | 2006-10-25 |
CA2553915A1 (en) | 2005-08-18 |
BRPI0507518A (pt) | 2007-07-03 |
US20070161642A1 (en) | 2007-07-12 |
RU2339381C2 (ru) | 2008-11-27 |
AU2005210326B2 (en) | 2009-10-22 |
TW200530218A (en) | 2005-09-16 |
CA2553915C (en) | 2010-06-01 |
CN1905882A (zh) | 2007-01-31 |
KR20070029133A (ko) | 2007-03-13 |
HK1098377A1 (en) | 2007-07-20 |
RU2006132389A (ru) | 2008-03-20 |
BRPI0507518A8 (pt) | 2015-12-01 |
TWI357409B (en) | 2012-02-01 |
JPWO2005074938A1 (ja) | 2007-09-13 |
JP4783152B2 (ja) | 2011-09-28 |
IL176795A0 (en) | 2006-10-31 |
AU2005210326A1 (en) | 2005-08-18 |
WO2005074938A1 (ja) | 2005-08-18 |
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