CN101194857A - Laser lancet - Google Patents
Laser lancet Download PDFInfo
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- CN101194857A CN101194857A CNA2007101255671A CN200710125567A CN101194857A CN 101194857 A CN101194857 A CN 101194857A CN A2007101255671 A CNA2007101255671 A CN A2007101255671A CN 200710125567 A CN200710125567 A CN 200710125567A CN 101194857 A CN101194857 A CN 101194857A
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Abstract
The invention provides a laser scalpel, comprising a scalpel head which comprises a scalpel head body, energy transmission optical fiber and a light-beam emission angle control unit. The scalpel head body is used to support the energy transmission optical fiber and the light-beam emission angle control unit, wherein the energy transmission optical fiber comprises an emitting end face, and the light-beam emission angle control unit comprises tail optical fiber, a tail optical fiber emission end face and a reflecting face mirror. The reflecting face mirror and the emission end face are arranged relatively to form a certain angle, and a three dimensional micro-nano structure is arranged on at least one of the surfaces of the reflecting face mirror or tail optical fiber emission end face.
Description
Technical field
The present invention relates to fields such as medical science, biology, particularly a kind of laser scalpel that is used for fields such as medical science, biology.
Background technology
Laser light wave irradiating biological tissue can produce photicly come off, photic solidifying and effect such as photic vaporization, relevant principle has been used to make the laser scalpel with difference in functionality.Because laser surgery has traditional operation many advantages that still are beyond one's reach at present, the demand of laser scalpel grows with each passing day, the function kind is more and more specialized.Because various operation, the laser surgery cutter head that especially various endoscope operation need have different specific functions, thus innovation and creation many new laser scalpel technology.
In the practical operation, generally adopt laser instrument and the isolating working method of operation cutter head, satisfy different operation needs by the cooperation of both various different parameters.In the various parameters that influence scalpel greatest service energy and efficient, optical parametric is light beam parameters particularly, has directly determined the spatial light power density distribution of operative site as space angle, corrugated shape and the focal length etc. of light beam axis of symmetry.And for for structural certain point of the particular organisms of light beam irradiates, the optical effect that is produced be cut, solidify, the combination of vaporization or above-mentioned different effect, directly depend on the optical power density of this point to a great extent.Under the prerequisite that laser output power is determined, selection has the operation cutter head of particular beam (axis of symmetry) emission angle, corrugated shape and focal length combination, in fact be exactly to have selected converging or dispersing hot spot of specific dimensional orientation, given shape (as point-like, column, wire, planar etc.) and power density, thereby directly determined function, efficient and the operation ease of operation cutter head.
Existing laser operation apparatus adopts energy to transmit optical fiber mostly the luminous energy that laser instrument sends is sent to operative site.Because the optical fiber parameter difference, the output beam of fiber end face can present different spatial intensity distribution.It is circular that common energy optical fiber cross section mostly is, on this cross section refractive index be double-deck, evenly, concentric circles distributes, and is the symmetric horn-like or coniform spatial distribution of topping by the intensity distributions of sending light beam on the optical fiber outgoing end face about the fiber optic hub axle.It (can the extended line of optical fiber axle center on emitting facet be reference about the spatial spread angle of central symmetry axis that the purpose of cutter head design is to change light beam, largest extension semi-cone angle with light cone is represented), the shape of beam cross-section is (perpendicular to the cross section of fiber optic hub axle or its extended line, can be circular cone, elliptic cone etc.) with focal length (making it converge or disperse) toward different distances, thereby the control outgoing beam produces the energy density distribution that needs in the dimensional orientation and the zone of needs operation.
Although on principle, adopting micro-optical device to implement the optical fiber beam conversion is not difficult matter.But some specific function of the operation of endoscope particularly of performing the operation and rigorous environment condition have comparatively proposed strict requirement for the cutter head manufacturing technology.There is following deficiency in existing cutter head manufacturing technology:
1) generally by optical fiber being processed into certain shape or adopting methods such as spherical lens or face mirror to realize beam emissions angle dough-making powder shape, zooming transforms, there are problems such as complex structure, power attenuation are big in prior art.Even more serious is that prior art can only cause beam divergence mostly and be difficult to obtain light beam and converge.In order to obtain the necessary effects such as vaporization of operation, have to strengthen laser power, directly cause a series of problems such as the laser instrument cost improves, cutter head hot injury hidden danger strengthens, cutter head heat radiation difficulty.Because the endoscope structure is for the restriction of scalpel size, and conditionalities such as high power, hyperpyrexia, high humidity, comparatively complicated cutter head optical texture should not be adopted.In addition, in order to reduce the cross infection chance, disposable use as scalpel is first should not be adopted high complexity, expensive optical beam transformation scheme.So need badly than prior art more efficiently, simply, reliably, optical beam transformation scheme cheaply.
2) do not find up to now, the laser scalpel commodity of convertible side direction or front and back side emission light beam parameters.Although indivedual patents, relating to the light beam focal length as EP 0 372 362 A2 changes, promptly, fibre-optical drawing reaches the purpose that changes the light beam focal length by being increased spherical lens or optical fiber connector is made into spherical lens etc. coning or at optical fiber connector, but its structure is only applicable to the axial emission axial symmetry beam distribution of (beam cross section perpendicular to the fiber optic hub axle is point-like or garden speckle shape), is not suitable for side emission and non-axial symmetry (beam cross section perpendicular to fiber axis is wire or oval speckle shape) light beam.Other has indivedual patents, as US 5,366,456 relate to the front side to or rear side change to the light beam focal length, promptly change the focal length of emission light beam by the reflecting mirror that increases the specific ball symmetric shape at the optical fiber dead ahead, but its effect mainly be along the optical fiber axle center axially, and do not lie in side direction perpendicular to the axle center, and the reflecting surface mirror that is adopted is for spherical, can only conversion about fiber optic hub axisymmetric corrugated divergence or focal length, it can't be transformed into other shape, for example with optical fiber axis parallel or nonaxisymmetrical wire at an angle or oval columnated light beam.
3) optical surface of prior art laser surgery cutter head be subjected to easily in various degree contact staining and the cutter head hot injury relevant with contact staining.Because photic consolidation; if the operation cutter head exist one or more may with the contacted optical surface of illuminated biological tissue; as fiber end face, protection window, reflection or condenser lens surface etc., then irradiated biological tissue is as easy as rolling off a log to be sticked on the optical surface that is in contact with it.These pollutant directly block the emission light beam except meeting, cause outside the luminous power loss, if the heat that gathers on the pollutant can not get in time distributing, can cause optical surface even whole tool temperature to rise sharply, cause the hot injury or the stress damage of optical thin film or the material of optical surface own, the cutter head that finally causes performing the operation lost efficacy.Although indivedual patents, as US 5,366,456, the cutter head structure of the middle hollow out band louvre that is adopted is can reduce the chance that optical surface contacts with biological tissue simultaneously.But, because the cutter head structure complexity that this patent relates to is not easy to make the microsize that can satisfy endoscopic surgery.
4) there is cutter head hot injury hidden danger in various degree in the heat dissipation technology of existing cutter head.Except minute surface optics surface pollution recited above, if it is improper that the heat that operation technique itself as vaporization etc. are produced distributes, be enough to cause whole tool temperature cataclysm, the huge stress that is produced can cause cutter head distortion, parts explosion, come unstuck etc., finally can cause cutter head to lose efficacy, even cause contingency.Although partial monopoly such as US 5,366,456, even designed the heat dissipation channel of variable aperture, because the cutter head complicated integral structure is not easy miniaturization, this structure is difficult to expection for the practicality of endoscope operation cutter head heat radiation aspect.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art, the invention provides the laser scalpel of a kind of may command beam emissions angle, face shape and focal length.
The technical solution adopted for the present invention to solve the technical problems is: it comprises cutter head, described cutter head comprises the cutter head main body, energy transmits optical fiber and beam emissions angle control unit, described cutter head main body is used to support this energy and transmits optical fiber and beam emissions angle control unit, described energy transmits optical fiber and comprises emitting facet, described beam emissions angle control unit comprises optical fiber pigtail, tail optical fiber emitting facet and reflecting surface mirror, described reflecting surface mirror and this emitting facet are oppositely arranged and are angled, and at least one surface is provided with three-dimensional micro-nano structure in the surface of described reflecting surface mirror or tail optical fiber emitting facet.
The scheme that the present invention solves further technical problem is: described optical fiber pigtail and tail optical fiber emitting facet are vertically fibre core and covering to be processed into certain angle and diameter Distribution.
The scheme that the present invention solves further technical problem is: described reflecting surface mirror comprise a plane or curved mirror separately or with lens or other arrangement of mirrors, described mirror can be plane, curved surface, sphere or ellipsoid.
The scheme that the present invention solves further technical problem is: described three-dimensional micro-nano structure is the palisade groove structure that is periodic distribution.
The scheme that the present invention solves further technical problem is: described palisade groove structure comprises center groove and side trench, described center groove is positioned on the axis of symmetry that energy transmits optical fiber and runs through whole palisade groove structure, and described side trench is positioned at the both sides of this center groove and is symmetrical distribution about center groove.
The scheme that the present invention solves further technical problem is: the thickness of described three-dimensional micro-nano structure is 0.1 to 10 times of optical maser wavelength, and the degree of depth of described side trench is 0.1 to 10 times of optical maser wavelength.
The scheme that the present invention solves further technical problem is: described three-dimensional micro-nano structure is circular or oval-shaped.
The scheme that the present invention solves further technical problem is: will be positioned at cutter head main body on the beam emissions path and other optical texture hollow outs, and make not have the optics or the body structure surface that can directly contact with biological tissue in the emission light beam coverage.
The scheme that the present invention solves further technical problem is: other parts of this laser scalpel are hollow out as far as possible, and it is streamlined to guarantee that as far as possible hollow out position and optical surface together constitute.
The scheme that the present invention solves further technical problem is: wherein this cutter head main body all adopts stainless steel material or ceramic material.
The scheme that the present invention solves further technical problem is: the end structure of described emitting facet is processed into one of circular cone table top, oval oblique section, oval taper tangent plane or hemisphere face
Compared to prior art, laser scalpel of the present invention transmits on the end face of optical fiber by the energy at cutter head, perhaps be positioned on the reflecting surface mirror or tail optical fiber emitting facet that energy transmits the beam emissions angle control unit with certain angle and curved surface face type of optical fiber axis of symmetry on along the line, the three-dimensional micro-nano structure that processing has the certain surface shape and the degree of depth is as the palisade groove structure.This three dimensional structure and incident beam with micro/nano-scale interacts, in theory not only can be with the incident beam directional transmissions to the space any direction, and the focal length of the space divergence angle of the size of its diffraction pattern or its emission light beam or its emission light beam, and the shape of cross section of emission light beam can be fully by this three-dimensional micro-nano structure control, and needn't increase other optics in addition.
Description of drawings
Fig. 1 is the structural representation of laser scalpel of the present invention.
Fig. 2 is another structural representation of laser scalpel of the present invention.
Fig. 3 a to Fig. 3 d is the shape and the effect structure chart of the three-dimensional micro-nano structure of laser scalpel of the present invention.
Fig. 4 is the another kind of shape and the effect structure chart of the three-dimensional micro-nano structure of laser scalpel of the present invention.
The specific embodiment
Laser scalpel of the present invention comprises cutter head; Fig. 1 is the cutter head optics overall construction drawing of laser scalpel of the present invention; this cutter head comprises supporting construction 11; cutter head main body 12; focus on shaping device 13; optical cable internal layer lapping 14, energy transmits optical fiber 15, optical cable outer layer protective sleeve 16 and beam emissions angle control unit 17.Described energy transmits optical fiber 15 and comprises emitting facet.Described beam emissions angle control unit 17 comprises vertically optical fiber pigtail, tail optical fiber emitting facet and the reflecting surface mirror that fibre core and covering is processed into certain angle and diameter Distribution, and optics or the metallic film with three-dimensional micro-nano structure is set on the surface of described tail optical fiber emitting facet, reflecting surface mirror.Described reflecting surface mirror and this emitting facet is angled is oppositely arranged.
This reflecting surface mirror comprise a plane or curved reflector separately or with lens or other arrangement of mirrors, described reflecting mirror can be plane, curved surface, sphere or ellipsoid.
Wherein 15 emissions of energy transmission optical fiber are mainly used in the laser beam that laser instrument is sent and conduct to this cutter head, and the end of energy transmission optical fiber 15 can be processed into the plane perpendicular to optical fiber fiber core axis of symmetry.
Described cutter head main body 12 is used for fixing supporting construction 11, and energy transmits optical fiber 15, focuses on shaping device 13 and beam emissions angle control unit 17.Simultaneously, consider that the structure of this cutter head main body 12 and material should avoid producing optical surface pollution and associated hot damage thereof as far as possible, and should finish the needed heat conduction of whole cutter head, heat sinking function for heat radiation.
Focus on shaping device 13 and cooperate, finish beam shaping and focusing function with energy transmission optical fiber 15.Described focusing shaping device 13 is provided with the metallic film (not indicating) with three-dimensional micro-nano structure, and its structure and functional schematic see Fig. 3 a to Fig. 3 d for details.The function that focuses on shaping device 13 is will focus on the face fractal transform from the awl tubular laser beam of optical fiber etc. by the metallic film that its surface has a specific micro-nano structure, makes it to be pooled to space particular orientation and scope with perform the operation needed corrugated shape and focal length.
Among Fig. 1, beam emissions angle control unit 17 is mainly used in the metallic film with micro-nano structure that is positioned at energy transmission optical fiber 15 surfaces and cooperates, and further finishes the control of beam emissions angle.This beam emissions angle control unit 17 comprise a plane or curved reflector separately or with lens or other arrangement of mirrors, its function be by will reflect from the awl tubular laser beam of optical fiber, refraction etc., make it needed to perform the operation (light beam axis of symmetry) angle and be pooled to the space particular orientation.
Obviously, focus on shaping device 13 and beam emissions angle control unit 17 among Fig. 1 except finishing needed optical beam transformation function, the material of device itself and supporting construction thereof should afford high temperature, high humidity and the comparatively violent temperature and the STRESS VARIATION etc. of generation in the middle of the operation process.
Described metallic film with three-dimensional micro-nano structure also can be arranged on the surface of beam emissions angle control unit 17, is used for the laser that energy transmission optical fiber sends is controlled, and makes the rising angle of laser reach needs.
Certainly, in order to satisfy the needs in the actual operation, described three-dimensional micro-nano structure can be arranged on the end face that energy transmits optical fiber simultaneously and on the reflecting surface of beam emissions angle control unit, the process of its principle and work is similar to top description.
Laser scalpel of the present invention transmits on the end face of optical fiber by the energy at cutter head, perhaps transmit on the beam emissions angle control unit with certain angle and curved surface face type of optical fiber axis of symmetry on along the line being positioned at energy, the three-dimensional micro-nano structure that processing has the certain surface shape and the degree of depth is as the palisade groove structure.This three dimensional structure and incident beam with micro/nano-scale interacts, not only the incident beam orientation can be diffracted into the space any direction in theory, and the focal length of the space divergence angle of the size of its diffraction pattern or its emission light beam or its emission light beam, and the shape of cross section of emission light beam can be fully by this three-dimensional micro-nano structure control, and needn't increase other optics in addition.
The three-dimensional micro-nano structure of above-mentioned laser scalpel can be taked two kinds of specific implementation methods:
First method, energy is transmitted optical fiber be processed into end face perpendicular to optical fiber symmetry axle center, processing has the metallic film of certain three dimensional structure on end face, adopt different three dimensional structures, can make the emission light beam have different face shape, focal length and spatial distribution, even can produce the diffracted beam distribution that surmounts the diffraction theory expection, and promptly the light beam through the effect of micro/nano-scale three dimensional structure does not have the desired diffraction secondary lobe of traditional diffraction theory, and the emission beam angle is concentrated.Illustrate, adopt the three-dimensional micro-nano structure that is positioned at optical fiber surface shown in Fig. 3 a, Fig. 3 b and Fig. 3 d, the beam cross-section that sends is distributed shown in Fig. 3 c.Wherein, described thickness and the optical maser wavelength suitable (for example, the 0.1-10 of wavelength is doubly) of performing the operation and being adopted with metallic film 31 of three-dimensional micro-nano structure, its lower surface 34 overlaps with the upper surface that energy transmits optical fiber, and its material is a metal, as gold.Three-dimensional micro-nano structure on the upper surface of this metallic film 31 is the palisade groove structure that is periodic distribution, a center groove 32 that wherein is positioned on the optical fiber axis of symmetry runs through whole this metallic film 31, other groove 33 be positioned at this center groove 32 about, the degree of depth of this groove 33 approximates 0.1-10 times of optical maser wavelength, and the groove 33 of the right and left is symmetrical distribution about center groove 32.So-called palisade groove is periodic distribution, is meant from the vertical dimension between the groove 37 and 38 of these metallic film 31 upper surfaces to equal vertical dimension between groove 38 and 39.The cycle of described palisade groove can be accomplished 1/10th of optical maser wavelength, forms super diffraction.At the micronano optical manufacture field, the design parameter of said structure can obtain according to the known theory and the computational methods in this field, and the processing of relevant structure can be adopted main technique, flow process realizations such as imprint lithography.
Described three-dimensional micro-nano structure is also can be circular or oval, as shown in Figure 4.
Second method, the end that energy is transmitted optical fiber can be processed into certain optical texture, so that cooperate beam emissions angle control unit that is provided with on the optical fiber extended line and the three dimensional structure that is positioned at this cell surface, produce needed light beam face shape, focal length etc. with micro/nano-scale.Illustrate, the end structure that energy transmits optical fiber can be processed into circular cone table top, oval oblique section, oval taper tangent plane, hemisphere face etc.Above-mentioned different optical fiber connector structure is finished preliminary shaping, focusing and the emission angle adjustment of emission light beam.Have the metallic film of three dimensional structure by means of reflecting surface mirror surface, can make the emission light beam obtain further shaping, focal length and emission angle control, can produce the diffracted beam distribution that surmounts the diffraction theory expection equally.Its effect is given unnecessary details no longer one by one.Equally, at the micronano optical manufacture field, the design parameter of said structure can obtain according to the known theory and the computational methods in this field; The processing of relevant structure can be adopted technology, flow process realizations such as imprint lithography.
Above-mentioned two kinds of methods respectively have characteristics.First method, advantage are that the cutter head overall structure is simple, and beam energy is concentrated.But because need process the dimension micro-nano structure on fiber end face, need to adopt special fiber end face to tie up to receive process equipment and technology, relevant technologies is the known technology of this area.Second method, cutter head structure is complicated a little than first method, but easy a little with respect to fiber end face at mirror surface processing dimension micro-nano structure, relevant technologies also is the known technology of this area.Second method is with complicated a little structure, obtained bigger beam sizes, changeable emission angle and beam shape.
To be positioned at cutter head main body and optical texture hollow out on the beam emissions path, and make not have the optics or the body structure surface that can directly contact with biological tissue in the emission light beam coverage, from avoided the photocoagulation of biological tissue on optical surface at all.
Another benefit at hollow out position is to be convenient to Shui Qi Huawu heat to derive operative site by the endoscope reserving hole channel, therefore under the prerequisite that guarantees structural strength, except optical surface, other parts are hollow out as far as possible, and it is streamlined to guarantee that as far as possible hollow out position and optical surface together constitute.
Realize beam shaping and focus method in view of the cutter head opticator adopts two kinds of diverse ways,, specifically describe as follows so this part design need be mated:
At first, no matter adopt the sort of optical shaping method, the cutter head main body all can adopt the processing of existing goods mirror face stainless steel capillary tube to obtain.
Secondly, owing to adopt two kinds of different optical shaping methods, the light beam spatial distribution that is produced is different, so the structure hollow out need be taken into account both.The hollow out design principle is: which kind of situation no matter does not all exist the optics or the body structure surface that can directly contact with biological tissue in the emission light beam coverage.In other words, if exist and may cause the surface of blocking for light beam, no matter optical surface or stainless steel surfaces all should hollow out be handled.
In addition, when satisfying above-mentioned requirements, should make as far as possible that whole cutter head structure has enough support strengths, so that guarantee stable under the conditions such as high temperature, high humidity, heavily stressed variation, reliable, the safety of being supported on for relevant optical component.With the exception of this, the machine of establishing of whole cutter head structure, should be convenient to the reserving hole that whole knife head device passes existing endoscope or endoscope easily, be convenient to see through endoscope's observation that undergos surgery, be convenient to by be installed on the scalpel regulating handle to the operation cutter head move forward and backward, operations such as rotation, and be convenient to reserve with endoscope reserved water circulation road etc. and cooperate.
Cutter head main body 12 all can adopt stainless steel material or ceramic material, and beam emissions angle control unit all can adopt rustless steel or quartz material.The thermal coefficient of expansion of above-mentioned material is low, and conduction of heat and heat-radiating properties are good, stands hyperpyrexia, high humidity and heavily stressed variation impact that operation process produces.
The part Non-optical surfaces zone of cutter head main body is hollow out suitably, so that form the heat dissipation channel of the stream process that can supply water, walks the heat that operation process produces.Above-mentioned current can be sent and be reclaimed by the pod apertures that is positioned at endoscope or endoscope, and a water pump that is positioned at beyond the cutter head can be used for producing the current of certain flow rate.
Above content be in conjunction with concrete preferred implementation to further describing that the present invention did, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (11)
1. laser scalpel, it comprises cutter head, described cutter head comprises the cutter head main body, energy transmits optical fiber and beam emissions angle control unit, described cutter head main body is used to support this energy and transmits optical fiber and beam emissions angle control unit, described energy transmits optical fiber and comprises emitting facet, described beam emissions angle control unit comprises optical fiber pigtail, tail optical fiber emitting facet and reflecting surface mirror, described reflecting surface mirror and this emitting facet are oppositely arranged and are angled, and it is characterized in that: at least one surface is provided with three-dimensional micro-nano structure in the surface of described reflecting surface mirror or tail optical fiber emitting facet.
2. laser scalpel according to claim 1 is characterized in that: described optical fiber pigtail and tail optical fiber emitting facet are vertically fibre core and covering to be processed into certain angle and diameter Distribution.
3. laser scalpel according to claim 1 is characterized in that: described reflecting surface mirror comprise a plane or curved mirror separately or with lens or other arrangement of mirrors, described mirror can be plane, curved surface, sphere or ellipsoid.
4. laser scalpel according to claim 1 is characterized in that: described three-dimensional micro-nano structure is the palisade groove structure that is periodic distribution.
5. laser scalpel according to claim 4, it is characterized in that: described palisade groove structure comprises center groove and side trench, described center groove is positioned on the axis of symmetry that energy transmits optical fiber and runs through whole palisade groove structure, and described side trench is positioned at the both sides of this center groove and is symmetrical distribution about center groove.
6. laser scalpel according to claim 5 is characterized in that: the thickness of described three-dimensional micro-nano structure is 0.1 to 10 times of optical maser wavelength, and the degree of depth of described side trench is 0.1 to 10 times of optical maser wavelength.
7. laser scalpel according to claim 4 is characterized in that: described three-dimensional micro-nano structure is circular or oval-shaped.
8. laser scalpel according to claim 1, it is characterized in that: will be positioned at cutter head main body on the beam emissions path and other optical texture hollow outs, and make not have the optics or the body structure surface that can directly contact with biological tissue in the emission light beam coverage.
9. laser scalpel according to claim 8 is characterized in that: other parts of this laser scalpel are hollow out as far as possible, and it is streamlined to guarantee that as far as possible hollow out position and optical surface together constitute.
10. laser scalpel according to claim 1 is characterized in that: wherein this cutter head main body all adopts stainless steel material or ceramic material.
11. laser scalpel according to claim 1 is characterized in that: the end structure of described emitting facet is processed into one of circular cone table top, oval oblique section, oval taper tangent plane or hemisphere face.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101255671A CN101194857B (en) | 2007-12-28 | 2007-12-28 | Laser lancet |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101255671A CN101194857B (en) | 2007-12-28 | 2007-12-28 | Laser lancet |
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| CN101194857A true CN101194857A (en) | 2008-06-11 |
| CN101194857B CN101194857B (en) | 2010-06-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2007101255671A Expired - Fee Related CN101194857B (en) | 2007-12-28 | 2007-12-28 | Laser lancet |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102096156A (en) * | 2011-01-06 | 2011-06-15 | 南京大学 | Online light polarization controller based on optical fiber end face metal wire grating and manufacturing method thereof |
| CN102860872A (en) * | 2012-06-01 | 2013-01-09 | 首都医科大学 | Laser scalpel device |
| CN109044527A (en) * | 2018-08-17 | 2018-12-21 | 张云峰 | A kind of Intelligent Laser scalpel |
| CN109567931A (en) * | 2018-12-07 | 2019-04-05 | 中聚科技股份有限公司 | A kind of replaceable laser probe and device for laser therapy of the end with optothermal material |
| CN110537898A (en) * | 2019-09-06 | 2019-12-06 | 上海交通大学 | Manufacturing method of focus-adjustable photoacoustic endoscopic microscope |
| CN111772786A (en) * | 2019-04-04 | 2020-10-16 | 奥斯奥鹏河北医疗器械销售有限公司 | Surgical knife |
-
2007
- 2007-12-28 CN CN2007101255671A patent/CN101194857B/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102096156A (en) * | 2011-01-06 | 2011-06-15 | 南京大学 | Online light polarization controller based on optical fiber end face metal wire grating and manufacturing method thereof |
| CN102860872A (en) * | 2012-06-01 | 2013-01-09 | 首都医科大学 | Laser scalpel device |
| CN102860872B (en) * | 2012-06-01 | 2015-10-28 | 首都医科大学 | Laser scalpel device |
| CN109044527A (en) * | 2018-08-17 | 2018-12-21 | 张云峰 | A kind of Intelligent Laser scalpel |
| CN109044527B (en) * | 2018-08-17 | 2020-04-17 | 张云峰 | Intelligent laser scalpel |
| CN109567931A (en) * | 2018-12-07 | 2019-04-05 | 中聚科技股份有限公司 | A kind of replaceable laser probe and device for laser therapy of the end with optothermal material |
| CN111772786A (en) * | 2019-04-04 | 2020-10-16 | 奥斯奥鹏河北医疗器械销售有限公司 | Surgical knife |
| CN111772786B (en) * | 2019-04-04 | 2024-03-29 | 奥斯奥鹏河北医疗器械销售有限公司 | Surgical knife |
| CN110537898A (en) * | 2019-09-06 | 2019-12-06 | 上海交通大学 | Manufacturing method of focus-adjustable photoacoustic endoscopic microscope |
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| Publication number | Publication date |
|---|---|
| CN101194857B (en) | 2010-06-30 |
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