CN101732795B - Pacemaking generation device and control method thereof - Google Patents
Pacemaking generation device and control method thereof Download PDFInfo
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- CN101732795B CN101732795B CN 200810217603 CN200810217603A CN101732795B CN 101732795 B CN101732795 B CN 101732795B CN 200810217603 CN200810217603 CN 200810217603 CN 200810217603 A CN200810217603 A CN 200810217603A CN 101732795 B CN101732795 B CN 101732795B
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Abstract
The invention discloses a pacemaking generation device comprising an exciting source and an electrode terminal for contacting with a biosome, wherein the exciting source is used for providing pacemaking pulse for the pacemaking generation device and outputs the pacemaking pulse to the electrode terminal; the pacemaking generation device also comprises a control unit and an impedance detection unit; the impedance detection unit is connected with the control unit which is connected with the exciting source; and the control unit is used for responding the impedance detected by the impedance detection unit, calculating a target voltage value, converting the target voltage value into corresponding voltage control level, outputting the voltage control level to the exciting source and controlling the exciting source to output corresponding power. The pacemaking generation device can dynamically adjust the power output in time, thereby effectively reducing the power consumption of a circuit.
Description
[technical field]
The present invention relates to a kind of pacemaking generation device.
[background technology]
Often need to carry out external noinvasive pace-making to patient in clinical emergency aid and treatment occasion and obtain rescued effect timely, the advantage of external pace-making has: 1) need not conduit or acupuncture, to the human zero damage; 2) do not need to install conduit, operation fast; The effective treatment meanss of first aid diagnosis and treatment.Different from pace-making in body, adhesive type electrode terminal sheet is used in external pacemaker more, and during treatment, also mode in the body of human body impedance excursion, require external pacemaker can adapt to larger impedance ranges and the effective pulse of stable output.
External human body breast resistance scope is wide than the body internal impedance, general excursion is from 20 ohm～200 ohm, clinical effective stimulus pulse current excursion 5mA～200mA, for guaranteeing under maximum impedance, can export maximum effective current, the current impulse circuit for generating need to have the fan-out capability that transient power consumption reaches 8W so, if the actual patient impedance is little, as 20 ohm, the so actual useful power consumption that is used for pacemaker impulse only has 0.8W, both power consumptions differ 10 times, and other 7.2W power consumption will be by hot form consumption on the device of current impulse circuit for generating.
The shortcoming of this design is: the output of pacemaker can not change with the real-time impedance under different patients or patient's different conditions, may cause following problem: first, circuit devcie is the outer heat loss of commitment always, the circuit temperature rise, for reducing this temperature rise, need to increase fin to device and guarantee under the condition that works long hours, the temperature rise of chip can not surpass rated temperature, prevents that overtemperature from causing characteristic changing or the fault of device.The second, the power consumption of circuit is in relatively high level always.In clinical emergency treatment and treatment use occasion, instrument miniature portable, low-power consumption are the development trends of instrument.Especially to battery powered equipment, reduce effectively prolongs standby time of power consumption, can improve service efficiency.Its heating effect of low power consuming devices is also relatively low simultaneously, to accomplishing the small-sized and portable more favourable of equipment.
[summary of the invention]
Main purpose of the present invention solves the problems of the prior art exactly, and a kind of low-power consumption pacemaking generation device and control method thereof are provided.
for achieving the above object, the invention provides a kind of pacemaking generation device, comprise driving source and the electrode terminal that is used for contacting organism, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, described pacemaking generation device also comprises control unit and impedance acquiring unit, described impedance acquiring unit is connected with control unit, described control unit is connected with driving source, the impedance of the organism of described control unit responsive impedance acquiring unit output, calculate target voltage values, target voltage values is converted to corresponding Control of Voltage level, and the output voltage control level is to driving source, control the corresponding power of described driving source output.
In one embodiment, described control unit comprises computing module and a DA transducer, described computing module is used for calculating target voltage values, described target voltage values increases with the increase of the product of the pacemaker current value of the resistance value of impedance acquiring unit output and setting, a described DA transducer is used for the digital quantity of target voltage values is converted to the Control of Voltage level of simulation, and output to described driving source, control the corresponding pace-making driving voltage of described driving source output.
In one embodiment, described driving source comprises voltage source and current source, described voltage source provides driving voltage for described current source, described current source is for generation of the pacemaker impulse of setting width and frequency, a described DA transducer outputs to voltage source with the Control of Voltage level, controls the output voltage of voltage source.Described control unit also comprises the 2nd DA transducer, described the 2nd DA transducer is used for the pacemaker current value that the operator sets is converted to the Current Control level of simulation, and output to described current source according to the frequency of setting with pulse mode, control the pulse that current source output has predetermined pacemaker current and pacing frequency.
The present invention also provides a kind of pacemaking generation device control method, comprises the following steps:
Obtain the impedance of organism;
Output according to described impedance adjustment driving source.
In one embodiment, the output of adjusting driving source comprises the following steps: obtain predetermined pacemaker current value; Regulate the pace-making driving voltage of driving source output according to the product of described impedance and predetermined pacemaker current value.
In another kind of embodiment, the step of regulating the pace-making driving voltage according to the product of described impedance and predetermined pacemaker current value comprises the following steps:
Calculate target voltage values, the product that described target voltage values equals described impedance and predetermined pacemaker current value multiply by a coefficient adds a constant;
The digital quantity of target voltage values is converted to the Control of Voltage level of simulation;
Described driving source is according to pace-making driving voltage corresponding to Control of Voltage level output.
The invention has the beneficial effects as follows: the present invention determines the power stage of driving source according to the impedance parameter that is operated organism, for the large situation of external impedance excursion, also can guarantee to produce enough effective currents on the patient.For the large situation of impedance, by the dynamic adjustments driving source, make enough electric current fan-out capabilities.In the situation that resistance is little, circuit can in time dynamically be adjusted driving source output, effectively reduces circuit power consumption.In wide impedance variation scope, the dynamic adjustment of driving source, can make the work efficiency of circuit maintain a high level always, especially for small-sized or portable set, in the situation that powering quantity is suitable, this high efficiency pulse outputting unit can more effective output pacemaker impulse, effectively prolongs standby time, reduce the circuit thermal losses.This pulse generating circuit is particularly suitable for using in the large external pace-making occasion of impedance variation scope.
[description of drawings]
Fig. 1 is the theory diagram of a kind of embodiment of pacemaking generation device;
Fig. 2 is the voltage source structural representation of an embodiment of the present invention;
Fig. 3 is the current source structural representation of an embodiment of the present invention;
Fig. 4 is the theory diagram of the another kind of embodiment of pacemaking generation device;
Fig. 5 is the flow chart of an embodiment of the present invention;
Fig. 6 is the impedance detection cellular construction schematic diagram of an embodiment of the present invention;
Fig. 7 is the flow chart of the another kind of embodiment of the present invention;
Fig. 8 is the flow chart of another embodiment of the present invention.
[specific embodiment]
The application's feature and advantage will be elaborated by reference to the accompanying drawings by embodiment.
please refer to Fig. 1, pacemaking generation device comprises: driving source, the electrode terminal 10 that is used for the contact organism, control unit 11 and impedance acquiring unit, in the present embodiment, the impedance acquiring unit is impedance detection unit 12, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, described impedance detection unit 12 is connected with control unit 11, described control unit 11 is connected with driving source, described impedance detection unit 12 is for detection of the termination that is operated organism (for example patient) 20, the impedance of the organism that described control unit responsive impedance detecting unit detects, and output control signal, control the output of described driving source, by controlling the output of driving source, thereby control the power consumption of pacemaking generation device.In the present embodiment, described driving source comprises voltage source 13 and current source 14, and voltage source 13 provides driving voltage for current source 14, and current source 14 is used for producing according to operator's setting the pacemaker impulse of setting width and frequency.
In one embodiment, described control unit comprises computing module and a DA (digital-to-analogue) transducer, and a DA transducer can be realized by hardware configuration, also can pass through software set, can be hardware configuration independently, also can be integrated in the chip of control unit.Computing module can be separately a microprocessor, also can jointly be integrated into a microprocessor with a DA transducer.In advance, control unit can receive pacemaker current and the pacing frequency that the operator sets, and pacemaker current and pacing frequency are set according to different patients' concrete situation.Control unit calculates the resistance value that the measures pacemaker current by computing module and setting, obtain the target voltage values of the pace-making voltage source of needs, target voltage values increases with the increase of the product of the pacemaker current value of the resistance value of impedance detection unit inspection and setting, in one embodiment, the computing formula of target voltage values is:
Vout＝A*R*Iout+B
In formula, Vout is the driving voltage of voltage source output, and Iout is predetermined pacemaker current, and R is human body impedance, and A and B are coefficient.
Target voltage values Vout also can adopt R*Iout to calculate.But because current source has internal resistance, can consume one part of current, so the driving voltage Vout of voltage source output should have certain surplus, A and B can calculate according to circuit characteristic.
The one DA transducer is converted to the digital quantity of this target voltage values the Control of Voltage level Vout_DA of a simulation, output to voltage source, be used as the voltage reference of Voltage Feedback ring, then by the inverse-excitation converting topological structure, produce the drive current source required voltage.
Voltage source can adopt multiple circuit to realize, in one embodiment, the structural representation of voltage source as shown in Figure 2, operational amplifier U39 and audion Q7 consist of a current source, flow through the size of Q7 electric current by signal voltage (the being the Control of Voltage level) decision of a DA transducer output.The reference edge node Vref voltage stabilization of stabilivolt U38 is at 2.5V, so the output of pace-making voltage PACE_V+ and a DA transducer is linear scale.
After the pace-making voltage of having regulated voltage source output, control unit is again according to default pacemaker current value and pacing frequency, the Current Control level Iout_DA that the 2nd DA transducer by control unit converts a simulation to exports to adjustable current source, the control signal of the 2nd DA transducer output is sent with pulse mode, like this current source pacing frequency that just generation needs between patient's electrode slice and the pulse of pacemaker current.When the Iout_DA signal voltage is zero, stop pace-making output.
The 2nd DA transducer can be realized by hardware configuration, also can pass through software set, can be hardware configuration independently, also can be integrated in the chip of control unit.
Current source can adopt multiple circuit to realize, in one embodiment, the controllable current source structure chart mainly comprises amplifying circuit U31 and metal-oxide-semiconductor Q9 as shown in Figure 3, and Current Control level Iout_DA is input to the input of amplifying circuit U31.Metal-oxide-semiconductor Q9 exports pacemaker impulse.
By the impedance detection unit, obtain current interelectrode organism (for example human body) resistance value, adjust the driving voltage of voltage source according to the current value of human body impedance and needs, make voltage source output can satisfy the requirement of drive current load.Then controlling pacemaker current source frequency output size as required by control unit is the pacemaker impulse of Iout.In wide impedance variation scope, the voltage source capable of dynamic is adjusted, and can make the work efficiency of circuit maintain a high level always, effectively reduces the power attenuation in circuit.
In another kind of embodiment, also the connection of leading is judged.As shown in Figure 4, pacemaking generation device comprises voltage source 13, current source 14, electrode terminal 10, control unit 11, impedance detection unit 12 and relay 15, relay 15 is connected between voltage source 13, current source 14 and electrode terminal 10, the control end of relay 15 is coupled to control unit 11, described control unit 11 compares resistance value and the predetermined threshold value that impedance detection unit 12 detects, and switches switching on and off between state according to the comparative result control relay.If for example resistance value is less than predetermined threshold value, control relay is connected, thereby pacemaker impulse is applied on tested organism 20, if resistance value greater than predetermined threshold value, control relay disconnects, thereby stops pacemaker impulse being applied on tested organism 20.
Pacemaker comes the power of regulation output by the driving voltage of regulation output, thereby make output can follow the real-time impedance of tested organism and change, namely dynamically adjust the power consumption of pulse generating circuit, the power of the loose consumption of the forms such as circuit heat is saved, can effectively increase work efficiency, reduce the circuit heating, extend the machine working time.The workflow of pacemaker comprises the following steps as shown in Figure 5:
1, after receiving the instruction that pace-making begins, first obtain the real-time impedance R of impedance detection unit output.
2, whether judge real-time impedance R greater than predetermined threshold value, if so, illustrate to lead to come off, can stop pacemaker impulse being applied on tested organism, for example export control signal to relay by control unit, control relay disconnects, thereby pacemaker and tested organism are separated from.If impedance R does not exceed predetermined threshold value in real time, explanation is led connection normally, pacemaker impulse is applied on tested organism, for example exports control signal to relay by control unit, control relay is closed, thereby the pacemaker impulse of output is applied on tested organism.
3, calculate the Vout_DA controlled quentity controlled variable according to the real-time impedance R that detects and default pacemaker current value, the voltage of regulation voltage source output.
4, calculate the Iout_DA controlled quentity controlled variable according to default pacemaker current value, control the pacemaker impulse that current source output has electric current I out and setpoint frequency.
Judging whether also to need to export pacemaker impulse after each output pacemaker impulse, if need to the above-mentioned steps that circulates.Still Real-Time Monitoring impedance between the pacemaker impulse period of output, real-time resistance value and predetermined threshold value are compared, if resistance value less than predetermined threshold value, is applied to pacemaker impulse on tested organism, if resistance value greater than predetermined threshold value, stops pacemaker impulse being applied on tested organism.After pacemaker impulse is sent each time, according to current resistance value, recomputate the adjustment voltage of voltage source, and the value of the Vout_DA new according to result of calculation output, power consumption control is completed in Circuit tuning output.
A kind of implementation of impedance detection unit is to realize by hardware: convert impedance signal to level signal through described hardware impedance collection circuit, after the AD conversion, calculate resistance value by control unit according to the linear relationship of circuit.a kind of circuit structure of impedance detection unit as shown in Figure 6, comprise the carrier generator that is linked in sequence, capacitance coupling circuit, difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit, described carrier generator is for generation of high-frequency carrier signal, the high frequency carrier square-wave signal is to be produced by PWM, at first the square-wave signal of its generation is the pulse signal of 2.5V through MOSFET output same frequency and amplitude, square-wave signal after amplifying through amplifier is again followed and is oppositely amplified the pulse that is divided into the two-way opposite direction through amplifier respectively again through high pass and enters capacitance coupling circuit, the input of capacitance coupling circuit also the RA by representing respectively two limb leads and LL (RA is right arm, LL is left lower limb) input organism impedance signal, these two signal differentials obtain later on II guided wave shape signal.Capacitance coupling circuit is modulated to the organism impedance signal in high-frequency carrier signal, modulated human body impedance signal's carrier signal after buffering is amplified by difference amplifier, amplify through bandwidth-limited circuit again, output to half-wave rectifying circuit, one direction waveform through halfwave rectifier output enters into AD detector, this direct current signal and the human body impedance linear correlation of control unit again through the low-pass filter circuit rectification output dc waveform of back.
When the output of impedance detection unit be analogue signal the time, the impedance detection unit first outputs to the AD detector with impedance signal, the AD detector can be the part of control unit, can be also an individual devices that is positioned at outside control unit.AD converter is the digital quantity of can controlled unit (for example CPU) processing with analog signal conversion.
The another kind of implementation of impedance detection unit is indirectly to utilize other calculation of parameter to obtain resistance value.For example impedance equals to be applied to the voltage at impedance two ends divided by the electric current that flows through impedance.the impedance detection unit comprises voltage acquisition module, current acquisition module and resistance calculations module, described voltage acquisition module is used for gathering the voltage that is applied on organism, described current acquisition module is used for acquisition stream through the electric current of organism, the input of described resistance calculations module connects respectively voltage acquisition module and current acquisition module, the outfan of described resistance calculations module is coupled to control unit, the electric current that the voltage and current acquisition module that described resistance calculations module responds voltage acquisition module gathers gathers, calculate resistance value, and resistance value is outputed to control unit.Can obtain resistance value accurately by voltage and current being sampled and calculating also.
Itself just need to carry out Real-Time Monitoring to the current/voltage of the human body of flowing through in the pace-making process, whether normal with the treatment electric current that judges current output, be applied to the voltage safety whether on human body.Body current and body voltages convert corresponding magnitude of voltage to by special testing circuit, giving control unit after this value is changed through AD processes, control unit obtains current body current value and body voltages value according to sampled result, and whether independent judgment electric current and voltage is normal.The ratio that calculates simultaneously electric current and voltage just can obtain the human body impedance value.Its flow chart as shown in Figure 7, current impedance is surveyed in the little current impulse that can first send a utmost point short time in beginning before pace-making, if impedance is normally according to this impedance initialization voltage source, if impedance is extremely stop pace-making.In the process that pacemaker impulse sends, there is electric current to be applied on human body, the method for this current-voltage sampling computing impedance can be carried out in real time, if it is excessive human body impedance to be detected, can judge the current stateful connection that leads undesired, stops pace-making.If impedance is normal, in the pacemaker impulse gap, recomputate the control voltage Vout value in pacemaker current source, and regulate Vout_DA, make the output of voltage source drive current source produce the suitable voltage of setting electric current on human body.After the voltage adjustment was complete, control unit according to pacemaker current Iout value, was controlled the pacemaker impulse that width is set in Iout_DA output when next pacemaker impulse output.
In other embodiment, the impedance detection unit can also adopt direct hardware impedance detection circuit and the common human body impedance of two kinds of methods of software parameter detection computations indirectly, receive pace-making begin before by hardware impedance detection unit inspection human body impedance, voltage source is initialized.Calculate human body impedance by software detecting method after pace-making begins, complete the dynamic adjustment to voltage source V out.The human body impedance of hardware impedance detection unit inspection and the human body impedance of indirect software parameter detection computations can also be compared in the pace-making process, if when the result difference that arrives of two kinds of detection methods is larger, can have judged a kind of impedance detection method and occur abnormal.Control flow as shown in Figure 8.
In above-described embodiment, the impedance acquiring unit adopts the impedance detection unit, can detect the real-time impedance that is operated organism, and output can be become according to the impedance of different organisms or the impedance under same organism different conditions.Mode as an alternative, the impedance acquiring unit can also be the impedance memory element, for the patient of long-term inpatients, can its resistance value is pre-stored in the impedance memory element, when this patient is carried out pace-making, can read its resistance value and be used for the pace-making operation from the impedance memory element, this resistance value is used for the beginning of pace-making as initial value, in the pace-making process, can detect in real time patient's resistance value, and the resistance value that records is updated in the impedance memory element, be used for the control of driving source.
In above-described embodiment, be used for the relay of pacemaker and organism isolation can also be replaced with other switch.
In sum, capable of dynamic of the present invention is adjusted the pacemaker impulse circuit for generating, make pulse at larger impedance ranges stable output, effectively reduce the power consumption of pulse generating circuit, when impedance is little, just can produce the pacemaker impulse that needs with low-voltage, when impedance is higher, heighten voltage source output, make current source have enough carrying load abilities, produce the pacemaker impulse of satisfying the demand.
Above content is in conjunction with concrete preferred implementation further description made for the present invention, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (13)
1. pacemaking generation device, comprise driving source and the electrode terminal that is used for contacting organism, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, it is characterized in that: described pacemaking generation device also comprises control unit and impedance acquiring unit, described impedance acquiring unit is connected with control unit, described control unit is connected with driving source, the impedance of the organism of described control unit responsive impedance acquiring unit output, calculate target voltage values, described target voltage values is converted to corresponding Control of Voltage level, and export described Control of Voltage level to driving source, control the corresponding power of described driving source output, described impedance acquiring unit is the impedance detection unit for detection of the real-time resistance value of organism, described impedance detection unit comprises the carrier generator that is linked in sequence, capacitance coupling circuit, difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit, described control unit also comprises the AD detector, described carrier generator is for generation of high-frequency carrier signal, and the pulse that is divided into the two-way opposite direction enters capacitance coupling circuit, the input of described capacitance coupling circuit also receives the organism impedance signal, modulated the carrier signal order of organism impedance signal through difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit are processed, the output dc waveform is to described AD detector.
2. pacemaking generation device as claimed in claim 1, it is characterized in that: described control unit comprises computing module and a DA transducer, described computing module is used for calculating target voltage values, described target voltage values increases with the increase of the product of the pacemaker current value of the resistance value of impedance acquiring unit output and setting, a described DA transducer is used for the digital quantity of target voltage values is converted to the Control of Voltage level of simulation, and output to described driving source, control the corresponding pace-making driving voltage of described driving source output.
3. pacemaking generation device as claimed in claim 2 is characterized in that: the product that described target voltage values equals the pacemaker current value of resistance value and setting multiply by a coefficient adds a constant.
4. pacemaking generation device as claimed in claim 2, it is characterized in that: described driving source comprises voltage source and current source, described voltage source provides driving voltage for described current source, described current source is for generation of the pacemaker impulse of setting width and frequency, a described DA transducer outputs to voltage source with the Control of Voltage level, controls the output voltage of voltage source.
5. pacemaking generation device as claimed in claim 4, it is characterized in that: described control unit also comprises the 2nd DA transducer, described the 2nd DA transducer is used for the pacemaker current value that the operator sets is converted to the Current Control level of simulation, and output to described current source according to the frequency of setting with pulse mode, control the pulse that current source output has predetermined pacemaker current and pacing frequency.
6. pacemaking generation device as described in any one in claim 1-5, it is characterized in that: described pacemaking generation device also comprises the switch that is connected between driving source and electrode terminal, the control end of described switch is coupled to control unit, described control unit compares resistance value and the predetermined threshold value of impedance detection unit inspection, switches switching on and off between state according to the comparative result gauge tap.
7. output control method based on the described pacemaking generation device of any one in claim 1-6 comprises the following steps:
Obtain the impedance of organism;
Output according to described impedance adjustment driving source.
8. control method as claimed in claim 7, it is characterized in that: the output of described adjusting driving source comprises the following steps: obtain predetermined pacemaker current value; Regulate the pace-making driving voltage of driving source output according to the product of described impedance and predetermined pacemaker current value.
9. control method as claimed in claim 8 is characterized in that: the step of regulating the pace-making driving voltage according to the product of described impedance and predetermined pacemaker current value comprises the following steps:
Calculate target voltage values, the product that described target voltage values equals impedance and predetermined pacemaker current value multiply by a coefficient adds a constant;
The digital quantity of described target voltage values is converted to the Control of Voltage level of simulation;
Described driving source is according to pace-making driving voltage corresponding to Control of Voltage level output.
10. control method as claimed in claim 8 or 9 is characterized in that: described impedance is the real-time impedance of the organism that detects.
11. control method as claimed in claim 10, it is characterized in that: further comprising the steps of in the process of described output pacemaker impulse: described real-time resistance value and predetermined threshold value are compared, if described resistance value is less than predetermined threshold value, pacemaker impulse is applied on tested organism, if described resistance value greater than predetermined threshold value, stops pacemaker impulse being applied on tested organism.
12. control method as claimed in claim 11, it is characterized in that: further comprising the steps of before the output pacemaker impulse: the real-time impedance of obtaining organism, described real-time resistance value and predetermined threshold value are compared, if described resistance value is less than predetermined threshold value, pacemaker impulse is applied on tested organism, if described resistance value greater than predetermined threshold value, stops pacemaker impulse being applied on tested organism.
13. control method as claimed in claim 12, it is characterized in that: the described step of obtaining the real-time impedance of organism comprises the following steps: the voltage that is applied on tested organism is sampled, electric current on the tested organism of flowing through is sampled, described voltage is obtained resistance value divided by electric current.
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|---|---|
| CN101732795A (en) | 2010-06-16 |
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