CN101773701A - Nerve stimulator - Google Patents
Nerve stimulator Download PDFInfo
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- CN101773701A CN101773701A CN201010000519A CN201010000519A CN101773701A CN 101773701 A CN101773701 A CN 101773701A CN 201010000519 A CN201010000519 A CN 201010000519A CN 201010000519 A CN201010000519 A CN 201010000519A CN 101773701 A CN101773701 A CN 101773701A
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Abstract
The invention provides a nerve stimulator, which comprises an internal antenna, a forward path and a stimulating electrode which are connected in sequence and also comprises a backward path which is connected between the stimulating electrode and the internal antenna, wherein the internal antenna receives an external radio frequency antenna signal and the forward path generates a stimulating current for stimulating nerves according to the received antenna signal; the stimulating electrode stimulates the nerves according to the simulating current which is generated by the forward path; the backward path is used for monitoring and measuring physical and physiological parameters related to electrode stimuli and feeding the physical and physiological parameters back to an external antenna by an internal antenna. The nerve stimulator can transmit a forward signal from the external to the internal and transmit a backward signal from the internal to the external by using only one set of internal and external antennas, so the information feedback of the nerve simulator can be realized. Thus, a doctor or a user can obtain more internal physical and physiological parameter information to control and adjust the stimulator according to the information.
Description
Technical field
The present invention relates to the artificial implant technical field, relate in particular to a kind of nerve stimulator.
Background technology
Nerve stimulator directly stimulates the relevant nerve of human body with electric current, thereby partly or entirely loses the human organ of normal function or the effective efficiency of tissue for band.At present typical nerve stimulator has: be implanted in the cochlear implantation prosthesis that the human body internal ear is used to stimulate auditory nerve, or claim cochlear implant; Be implanted in retina and be used to retina stimulator that stimulates optic nerve etc.
Nerve stimulator is usually by internal antenna, and electric stimulator and stimulating electrode are formed, and wherein internal antenna is used to receive the signal of external emission, and electric stimulator produces corresponding stimulating current, and electrode reaches nervous tissue with electricity irritation.
Nerve stimulator belongs to safety and the highest active three class implants of effectiveness requirement.Based on the particularity of its application, not only require the nerve stimulation function should be safe and effective, and wish can be in the duty of external monitoring stimulator, and the relevant human body physiological parameter of energy measurement.
Summary of the invention
Technical problem to be solved by this invention is, a kind of nerve stimulator is provided, be used to solve existing nerve stimulator can only unidirectional enforcement to the galvanism of nerve, and can't know the problem of the physiological parameter of the physical parameter of nerve stimulator and corresponding human body.
For solving the problems of the technologies described above, the invention provides a kind of nerve stimulator, comprise the internal antenna, through path, the stimulating electrode that are linked in sequence, also comprise the backward channel that is connected between stimulating electrode and the internal antenna, wherein:
Described internal antenna receives external radio-frequency antenna signal, and through path produces according to the aerial signal that receives and is used for neuroactive stimulating current; Stimulating electrode stimulates nerve according to the stimulating current that through path produces; Backward channel is used to monitor physics and the physiological parameter relevant with electricity irritation with measurement, and gained physics and physiological parameter are fed back to external antenna by internal antenna.
Further, described backward channel comprises:
Physics and physiological parameter detecting unit are used to detect stimulating electrode in Electric Field Distribution on each electrode of the impedance between the nervous tissue, stimulating current, neural to the reaction of electricity irritation and the duty of through path;
Coding/communication unit is used for detected physics and physiological parameter are carried out mould/number conversion, parallel/serial conversion, Frame coding and storage successively, and is transferred to external antenna with the reverse telemetry that the load-modulate mode will be stored from internal antenna.
Further, described physics and physiological parameter detecting unit comprise:
Three select a selector switch, are used for selecting a parameter to send into backward channel from electrode impedance, Electric Field Distribution and three kinds of parameters of nerves reaction; Programmable amplifier is used for selecting a selector switch to select the amplification that gains of the parameter signals of output to described three; N selects 1 selector switch, is used for the parameter signal after the gain amplification is optionally monitored the duty of monitoring nerve stimulator inside; Low pass filter able to programme is used for N is selected the selected parameter signal of 1 selector switch, carries out bandpass filtering, exports filtered signal to coding/communication unit.
Further, described physics and physiological parameter detecting unit comprise:
A/D converter is used for the reverse signal by physics and the input of physiological parameter detecting unit is converted to digital quantity by analog quantity;
Parallel/serial convertor, be used for the parallel output data of A/D converter is converted to serial data;
The Frame encoder is used for the serial data of described walking abreast/serial convertor output is added frame synchronization coding and parity check code;
Data storage is used for the reverse link parameter data after the Frame encoder encodes are stored;
The reverse data manipulator is used for reading the reverse link parameter data from data storage, and described reverse link parameter data are carried out modulation treatment, transfers to the reverse link parameter signal after the modulation external via internal antenna.
Further, described reverse data manipulator is in the mode of load-modulate the reverse digital signal in the memorizer to be modulated.Described reverse data manipulator utilizes in the memorizer opening and closing of reverse Digital Signals modulation switch, modulation load is inserted from the intrinsic load of internal antenna or disconnects.
Further, described through path comprises:
The energy acquiring unit is used for obtaining energy from the radiofrequency signal of external emission, after voltage-regulation, for whole nerve stimulator provides power supply;
Detecting signal unit is used for detecting fundamental frequency signal and clock signal from the radiofrequency signal carrier wave of external emission, and the fundamental frequency data signal is sent to signal decoding unit;
Signal decoding unit is used for from every information of the fundamental frequency data flow extraction electric stimulation pulse of detecting signal unit output, and the every information of electric stimulation pulse is sent to security control unit and electric stimulator;
Security control unit is used to check the effectiveness of the every information of electric stimulation pulse;
Electric stimulator is used under security control unit control, to the boost pulse that meets effectiveness in the electricity irritation of specifying stimulating electrode to produce required current amplitude, pulse width and stimulus frequency.
Nerve stimulator of the present invention, can utilize backward channel to realize to the collection of the human body physiological parameter under the stimulating electrode effect and the collection of stimulator self physical parameter, and will gather the gained parameter and feed back to external antenna by internal antenna, thereby make patient or doctor can know the corresponding information of nerve stimulation, help to adjust the user mode of nerve stimulator.
The present invention only needs can realize from external to intravital the forward signal transmission and from transmitting to external reverse signal in the body once cover internal antenna and external antenna.Thereby can realize the information feedback of nerve stimulator,, be used for carrying out the control and the adjustment of stimulator with reference to these information so that know more internal physical and physiological parameter information for doctor or user.
Description of drawings
Fig. 1 is the nerve stimulator sketch map of double band through path of the present invention and backward channel;
Fig. 2 is the functional block diagram of through path 102 in the nerve stimulator;
Fig. 3 is the functional block diagram of backward channel 104 in the nerve stimulator;
Fig. 4 is the physics of backward channel and the circuit structure diagram of physiological parameter detecting unit 104A;
Fig. 5 is the modular structure sketch map of the coding/communication unit 104B of backward channel;
Fig. 6 is the work sketch map of reverse data manipulator among the coding/communication unit 104B of backward channel.
The specific embodiment
For making the purpose, technical solutions and advantages of the present invention clearer, the present invention is described in further detail below in conjunction with accompanying drawing.
As shown in Figure 1, shown a kind of nerve stimulator with reverse telemetry function of the present invention, having comprised: internal antenna 101 is used to receive external radio-frequency antenna signal; Through path 102 is used for producing safety and effectively being used for neuroactive stimulating current according to the aerial signal that receives; Stimulating electrode 103 is used for according to the stimulating current that through path produces nerve being stimulated; Backward channel 104 is used to monitor physical parameter and the human body physiological parameter relevant with electricity irritation with measurement, and will monitor and measure the gained physical parameter and physiological parameter feeds back to external antenna and external monitoring equipment by internal antenna.
The circuit structure of described through path 102 as shown in Figure 2, through path 102 comprises:
Detecting signal unit 102B is used for detecting fundamental frequency signal and clock signal from the radiofrequency signal carrier wave by the external emission that internal antenna received, and the fundamental frequency data signal is sent to signal decoding unit 102C;
Security control unit 102D is used to check the effectiveness of the every information of electric stimulation pulse prevent to produce unsafe electricity irritation, for example: stimulate the positive and negative charge imbalance, overstimulation, ineffective stimulation parameter, electrode Electro-Static Discharge and unmatched extracorporeal treatment device;
As shown in Figure 3, the functional block diagram that has shown described backward channel 104.Described backward channel 104 comprises:
Physics and physiological parameter detecting unit 104A are used to detect stimulating electrode in Electric Field Distribution on each electrode of the impedance between the nervous tissue, stimulating current, neural to the reaction of electricity irritation and the duty of electric stimulator 102E.
Coding/communication unit 104B, be used for detected physics and physiological parameter carry out that mould/number changes, parallel/serial conversion, Frame coding and storage, and the reverse telemetry in the memorizer is transferred to external antenna from internal antenna in the load-modulate mode.
Further, the circuit structure of physics shown in Figure 3 and physiological parameter detecting unit 104A as shown in Figure 4.This physics and physiological parameter detecting unit 104A comprise:
1) three select a selector switch, be used for selecting a parameter to send into backward channel from electrode impedance, Electric Field Distribution and three kinds of parameters of nerves reaction, wherein, these three kinds of parameters have different signal amplitude scopes, and concrete scope can be regulated in conjunction with actual needs and is provided with;
2) 0-60dB programmable amplifier, according to described three parameter signals that select the selected output of a selector switch, by programmable amplifier to the amplification that gains of the parameter signal of this selection output, the gain multiple can concrete the setting be amplified to the appropriate signal amplitude with the reverse link parameter signal of selecting according to parameter type is different;
3) N selects 1 selector switch, is used for monitoring selectively the key job state of stimulator inside;
4) low pass filter able to programme is used for according to selected parameter signal, by the band connection frequency of programme-control wave filter, thus the interference of the outer frequency signal of filtering passband.The output signal of wave filter is delivered to coding/communication unit 104B.
As shown in Figure 5, shown the modular structure sketch map of the coding/communication unit 104B of backward channel, this coding/communication unit 104B comprises:
A) A/D converter (ADC) is used for the reverse signal of input is converted to digital quantity by analog quantity, to improve the reliability of reverse data transmission;
B) parallel/serial convertor is used for the parallel output data of ADC is converted to serial data, to adapt to the needs of follow-up data coding and transfer of data;
C) Frame encoder is used for the reverse link parameter data of described walking abreast/serial convertor output are added frame synchronization coding and parity check code, with the synchronous and data check of convenient external reverse signal receptor;
D) data storage is used for the reverse link parameter data behind the coding are stored;
E) reverse data manipulator is used for reading the reverse link parameter data from data storage, and described reverse link parameter data are carried out modulation treatment, will transfer to external via internal antenna through the repercussion parameter signal after the modulation.
As shown in Figure 6, the modulation system sketch map that has shown described reverse data manipulator.Wherein, the reverse data manipulator transfers to external antenna with the reverse digital signal in the memorizer by internal antenna in the mode of load-modulate.Reverse digital signaling zero in the memorizer/1 control modulation switch K leaving and closing, thereby a modulation load Rm is inserted from the intrinsic load Re of internal antenna or disconnects.
The signal amplitude of external antenna can change along with the load variations of internal antenna.The reverse signal testing circuit of extracorporeal circuit detects intravital reverse digital signal by the signal amplitude variation of detection bodies outside antenna.Adopt this reversing data transmission method, only need to realize from external to intravital the forward signal transmission and from transmitting to external reverse signal in the body once cover internal antenna and external antenna.Thereby can realize the information feedback of nerve stimulator,, be used for carrying out the control and the adjustment of stimulator with reference to these information so that know more internal physical and physiological parameter information for doctor or user.
The above is embodiments of the invention only, is not limited to the present invention, and for a person skilled in the art, the present invention can have various changes and variation.Within the spirit and principles in the present invention all, any modification of being done, be equal to replacement, improvement etc., all should be included within the claim scope of the present invention.
Claims (7)
1. a nerve stimulator is characterized in that, comprises the internal antenna, through path, the stimulating electrode that are linked in sequence, also comprises the backward channel that is connected between stimulating electrode and the internal antenna, wherein:
Described internal antenna receives external radio-frequency antenna signal, and through path produces according to the aerial signal that receives and is used for neuroactive stimulating current; Stimulating electrode stimulates nerve according to the stimulating current that through path produces; Backward channel is used to monitor physics and the physiological parameter relevant with electricity irritation with measurement, and gained physics and physiological parameter are fed back to external antenna by internal antenna.
2. nerve stimulator as claimed in claim 1 is characterized in that, described backward channel comprises:
Physics and physiological parameter detecting unit are used to detect stimulating electrode in Electric Field Distribution on each electrode of the impedance between the nervous tissue, stimulating current, neural to the reaction of electricity irritation and the duty of through path;
Coding/communication unit is used for detected physics and physiological parameter are carried out mould/number conversion, parallel/serial conversion, Frame coding and storage successively, and is transferred to external antenna with the reverse telemetry that the load-modulate mode will be stored from internal antenna.
3. nerve stimulator as claimed in claim 2 is characterized in that, described physics and physiological parameter detecting unit comprise:
Three select a selector switch, are used for selecting a parameter to send into backward channel from electrode impedance, Electric Field Distribution and three kinds of parameters of nerves reaction;
Programmable amplifier is used for selecting a selector switch to select the amplification that gains of the parameter signals of output to described three;
N selects 1 selector switch, is used for the parameter signal after the gain amplification is optionally monitored the duty of monitoring nerve stimulator inside;
Low pass filter able to programme is used for N is selected the selected parameter signal of 1 selector switch, carries out bandpass filtering, exports filtered signal to coding/communication unit.
4. nerve stimulator as claimed in claim 2 is characterized in that, described physics and physiological parameter detecting unit comprise:
A/D converter is used for the reverse signal by physics and the input of physiological parameter detecting unit is converted to digital quantity by analog quantity;
Parallel/serial convertor, be used for the parallel output data of A/D converter is converted to serial data;
The Frame encoder is used for the serial data of described walking abreast/serial convertor output is added frame synchronization coding and parity check code;
Data storage is used for the reverse link parameter data after the Frame encoder encodes are stored;
The reverse data manipulator is used for reading the reverse link parameter data from data storage, and described reverse link parameter data are carried out modulation treatment, transfers to the reverse link parameter signal after the modulation external via internal antenna.
5. nerve stimulator as claimed in claim 4 is characterized in that, described reverse data manipulator is in the mode of load-modulate the reverse digital signal in the memorizer to be modulated.
6. nerve stimulator as claimed in claim 5 is characterized in that, described reverse data manipulator utilizes in the memorizer opening and closing of reverse Digital Signals modulation switch, modulation load is inserted from the intrinsic load of internal antenna or disconnects.
7. nerve stimulator as claimed in claim 1 is characterized in that, described through path comprises:
The energy acquiring unit is used for obtaining energy from the radiofrequency signal of external emission, after voltage-regulation, for whole nerve stimulator provides power supply;
Detecting signal unit is used for detecting fundamental frequency signal and clock signal from the radiofrequency signal carrier wave of external emission, and the fundamental frequency data signal is sent to signal decoding unit;
Signal decoding unit is used for from every information of the fundamental frequency data flow extraction electric stimulation pulse of detecting signal unit output, and the every information of electric stimulation pulse is sent to security control unit and electric stimulator;
Security control unit is used to check the effectiveness of the every information of electric stimulation pulse;
Electric stimulator is used under security control unit control, to the boost pulse that meets effectiveness in the electricity irritation of specifying stimulating electrode to produce required current amplitude, pulse width and stimulus frequency.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010000519A CN101773701A (en) | 2010-01-11 | 2010-01-11 | Nerve stimulator |
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| CN201010000519A CN101773701A (en) | 2010-01-11 | 2010-01-11 | Nerve stimulator |
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| CN101773701A true CN101773701A (en) | 2010-07-14 |
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Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103608069A (en) * | 2011-03-24 | 2014-02-26 | 加利福尼亚理工学院 | Neurostimulator |
| CN103648583A (en) * | 2011-05-13 | 2014-03-19 | 萨鲁达医疗有限公司 | Method and apparatus for measurement of neural response - a |
| CN104080509A (en) * | 2011-07-29 | 2014-10-01 | 斯蒂维科技公司 | Remote control of power or polarity selection for a neural stimulator |
| CN104548344A (en) * | 2015-01-16 | 2015-04-29 | 江苏科技大学 | Injection type nerve stimulator with power supplied by radio frequency energy |
| CN104548346A (en) * | 2015-01-16 | 2015-04-29 | 江苏科技大学 | Injecting type nerve stimulator with electromagnetic coupling link power supply |
| CN104689472A (en) * | 2014-11-28 | 2015-06-10 | 苏州景昱医疗器械有限公司 | Electromagnetic type magnetic sensitive information feedback method and system |
| CN105012051A (en) * | 2015-06-30 | 2015-11-04 | 上海力声特医学科技有限公司 | Handshake method and handshake unit for cochlear implant communication protocol |
| CN105492066A (en) * | 2013-06-13 | 2016-04-13 | 迪彦希斯有限公司 | Method and apparatus for stimulative electrotherapy |
| CN105688333A (en) * | 2016-01-12 | 2016-06-22 | 中国人民解放军军事医学科学院基础医学研究所 | Nerve effect evaluation apparatus of external transcranial magnetic stimulation |
| US9409029B2 (en) | 2014-05-12 | 2016-08-09 | Micron Devices Llc | Remote RF power system with low profile transmitting antenna |
| CN106075721A (en) * | 2016-05-30 | 2016-11-09 | 沈阳弘鼎康医疗器械有限公司 | Impedometer |
| US9566449B2 (en) | 2011-01-28 | 2017-02-14 | Micro Devices, LLC | Neural stimulator system |
| CN106725419A (en) * | 2017-04-10 | 2017-05-31 | 陈东朝 | Amplifier of creatures' physical electric signals device |
| CN107073266A (en) * | 2014-09-23 | 2017-08-18 | 波士顿科学神经调制公司 | The system and method for the selection that user for receiving electrode list provides |
| US9789314B2 (en) | 2011-04-04 | 2017-10-17 | Micron Devices Llc | Implantable lead |
| CN107773238A (en) * | 2016-08-24 | 2018-03-09 | 四川锦江电子科技有限公司 | A kind of cardiac electrophysiology program stimulation instrument |
| US9974965B2 (en) | 2011-09-15 | 2018-05-22 | Micron Devices Llc | Relay module for implant |
| US10315039B2 (en) | 2011-01-28 | 2019-06-11 | Stimwave Technologies Incorporated | Microwave field stimulator |
| CN111202669A (en) * | 2020-01-08 | 2020-05-29 | 微传智能科技（上海）有限公司 | Body-embedded physical therapy training device and application thereof |
| US10953228B2 (en) | 2011-04-04 | 2021-03-23 | Stimwave Technologies Incorporated | Implantable lead |
| WO2022218125A1 (en) * | 2021-04-16 | 2022-10-20 | 北京领创医谷科技发展有限责任公司 | Implantable nerve stimulator system |
| US11583683B2 (en) | 2012-12-26 | 2023-02-21 | Stimwave Technologies Incorporated | Wearable antenna assembly |
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2010
- 2010-01-11 CN CN201010000519A patent/CN101773701A/en active Pending
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| US10471262B2 (en) | 2011-01-28 | 2019-11-12 | Stimwave Technologies Incorporated | Neural stimulator system |
| US9925384B2 (en) | 2011-01-28 | 2018-03-27 | Micron Devices Llc | Neural stimulator system |
| US9757571B2 (en) | 2011-01-28 | 2017-09-12 | Micron Devices Llc | Remote control of power or polarity selection for a neural stimulator |
| US9566449B2 (en) | 2011-01-28 | 2017-02-14 | Micro Devices, LLC | Neural stimulator system |
| US10315039B2 (en) | 2011-01-28 | 2019-06-11 | Stimwave Technologies Incorporated | Microwave field stimulator |
| US10420947B2 (en) | 2011-01-28 | 2019-09-24 | Stimwave Technologies Incorporated | Polarity reversing lead |
| CN103608069B (en) * | 2011-03-24 | 2017-03-29 | 加利福尼亚理工学院 | Nerve stimulator |
| CN103608069A (en) * | 2011-03-24 | 2014-02-26 | 加利福尼亚理工学院 | Neurostimulator |
| US10238874B2 (en) | 2011-04-04 | 2019-03-26 | Stimwave Technologies Incorporated | Implantable lead |
| US10953228B2 (en) | 2011-04-04 | 2021-03-23 | Stimwave Technologies Incorporated | Implantable lead |
| US11872400B2 (en) | 2011-04-04 | 2024-01-16 | Curonix Llc | Implantable lead |
| US9789314B2 (en) | 2011-04-04 | 2017-10-17 | Micron Devices Llc | Implantable lead |
| CN103648583B (en) * | 2011-05-13 | 2016-01-20 | 萨鲁达医疗有限公司 | For measuring method and the instrument of nerves reaction-A |
| CN103648583A (en) * | 2011-05-13 | 2014-03-19 | 萨鲁达医疗有限公司 | Method and apparatus for measurement of neural response - a |
| CN104080509B (en) * | 2011-07-29 | 2017-09-08 | 米克伦设备有限责任公司 | The remote control that power or polarity for nerve stimulator are selected |
| CN104080509A (en) * | 2011-07-29 | 2014-10-01 | 斯蒂维科技公司 | Remote control of power or polarity selection for a neural stimulator |
| US11745020B2 (en) | 2011-09-15 | 2023-09-05 | Curonix Llc | Relay module for implant |
| US9974965B2 (en) | 2011-09-15 | 2018-05-22 | Micron Devices Llc | Relay module for implant |
| US11583683B2 (en) | 2012-12-26 | 2023-02-21 | Stimwave Technologies Incorporated | Wearable antenna assembly |
| CN105492066A (en) * | 2013-06-13 | 2016-04-13 | 迪彦希斯有限公司 | Method and apparatus for stimulative electrotherapy |
| CN105492066B (en) * | 2013-06-13 | 2018-03-27 | 迪彦希斯有限公司 | For stimulating diathermic method and apparatus |
| US10258800B2 (en) | 2014-05-12 | 2019-04-16 | Stimwave Technologies Incorporated | Remote RF power system with low profile transmitting antenna |
| US9409029B2 (en) | 2014-05-12 | 2016-08-09 | Micron Devices Llc | Remote RF power system with low profile transmitting antenna |
| CN107073266A (en) * | 2014-09-23 | 2017-08-18 | 波士顿科学神经调制公司 | The system and method for the selection that user for receiving electrode list provides |
| CN107073266B (en) * | 2014-09-23 | 2020-08-11 | 波士顿科学神经调制公司 | System and method for receiving user-provided selections of electrode lists |
| CN104689472A (en) * | 2014-11-28 | 2015-06-10 | 苏州景昱医疗器械有限公司 | Electromagnetic type magnetic sensitive information feedback method and system |
| CN104548344A (en) * | 2015-01-16 | 2015-04-29 | 江苏科技大学 | Injection type nerve stimulator with power supplied by radio frequency energy |
| CN104548346A (en) * | 2015-01-16 | 2015-04-29 | 江苏科技大学 | Injecting type nerve stimulator with electromagnetic coupling link power supply |
| CN104548346B (en) * | 2015-01-16 | 2017-02-22 | 江苏科技大学 | Injecting type nerve stimulator with electromagnetic coupling link power supply |
| CN105012051A (en) * | 2015-06-30 | 2015-11-04 | 上海力声特医学科技有限公司 | Handshake method and handshake unit for cochlear implant communication protocol |
| CN105688333B (en) * | 2016-01-12 | 2019-02-26 | 中国人民解放军军事医学科学院基础医学研究所 | A kind of neural effect evaluating apparatus of external transcranial magnetic stimulation |
| CN105688333A (en) * | 2016-01-12 | 2016-06-22 | 中国人民解放军军事医学科学院基础医学研究所 | Nerve effect evaluation apparatus of external transcranial magnetic stimulation |
| CN106075721A (en) * | 2016-05-30 | 2016-11-09 | 沈阳弘鼎康医疗器械有限公司 | Impedometer |
| CN106075721B (en) * | 2016-05-30 | 2018-06-19 | 沈阳弘鼎康医疗器械有限公司 | Impedometer |
| CN107773238A (en) * | 2016-08-24 | 2018-03-09 | 四川锦江电子科技有限公司 | A kind of cardiac electrophysiology program stimulation instrument |
| CN106725419A (en) * | 2017-04-10 | 2017-05-31 | 陈东朝 | Amplifier of creatures' physical electric signals device |
| CN111202669A (en) * | 2020-01-08 | 2020-05-29 | 微传智能科技（上海）有限公司 | Body-embedded physical therapy training device and application thereof |
| WO2022218125A1 (en) * | 2021-04-16 | 2022-10-20 | 北京领创医谷科技发展有限责任公司 | Implantable nerve stimulator system |
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Address after: Yuhang District, Hangzhou City, Zhejiang Province, 311100 West No. 1500 Building 1 room 325 Applicant after: Zhejiang Nurotron Neural Electronic Technology Co., Ltd. Address before: 518, room 2, building 5, No. 6, Hangzhou economic and Technological Development Zone, Hangzhou, Zhejiang, 310011 Applicant before: Hangzhou Nuorkang Neural Electronic Technology Co., Ltd. |
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| CB03 | Change of inventor or designer information |
Inventor after: Sun Xiaoan Inventor after: Chen Hongbin Inventor after: Fu Qianjie Inventor before: Sun Xiaoan Inventor before: Zeng Fangang Inventor before: Chen Hongbin Inventor before: Fu Qianjie |
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| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: HANGZHOU NUORKANG NEURAL ELECTRONIC TECHNOLOGY CO., LTD. TO: ZHEJIANG NUROTRON NEURAL ELECTRONIC TECHNOLOGY CO., LTD. Free format text: CORRECT: INVENTOR; FROM: SUN XIAOAN CENG FANGANG CHEN HONGBIN FU QIANJIE TO: SUN XIAOAN CHEN HONGBIN FU QIANJIE |
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| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20100714 |