CN101883546A - 伤口包敷物 - Google Patents

伤口包敷物 Download PDF

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CN101883546A
CN101883546A CN2008801172243A CN200880117224A CN101883546A CN 101883546 A CN101883546 A CN 101883546A CN 2008801172243 A CN2008801172243 A CN 2008801172243A CN 200880117224 A CN200880117224 A CN 200880117224A CN 101883546 A CN101883546 A CN 101883546A
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wound
layer
sealant
absorbed layer
filter course
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CN101883546B (zh
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E·Y·哈特威尔
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Smith and Nephew PLC
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Abstract

本申请公开了用于包敷伤口的方法和装置。所述装置包括:包括至少一个孔口的密封层;在密封层上的吸收层,用于吸收伤口渗出物;和在吸收层上的使液体不可透过且气体可透过的过滤层。

Description

伤口包敷物
技术领域
本发明涉及用于包敷伤口的方法和装置和用于制造伤口包敷物的方法。特别地但非排他地,本发明涉及一种可用于身体局部负压(TNP)治疗过程中的伤口包敷物,其中,伤口包敷物自身用作废物罐以收集和储存从伤口部位移除的伤口渗出物。
背景技术
对于施加于伤口的身体局部负压(TNP)治疗以及旨在增强TNP治疗效果的其它治疗过程而言,存在许多与装置的提供及其使用方法有关的可用的现有技术。这种现有技术的示例包括下文列出和简要描述的现有技术。
通过减少组织水肿、促进血液流动和组织微粒化、移除过量渗出物,TNP治疗有助于使伤口闭合和愈合并可减少细菌增长以及伤口感染。而且,TNP治疗使伤口的外部干扰减小,从而促使愈合更快。
在国际专利申请WO 2004/037334中,描述了用于吸液、冲洗和清洁伤口的装置、伤口包敷物和方法。以非常概括的方式来说,该申请描述了:通过施加TNP治疗进行伤口处理,其中,对伤口吸液并进一步提供另外的流体来冲洗和/或清洁伤口,然后将包括伤口渗出物和冲洗流体的所述流体伤口通过吸液装置吸离并且通过用于使其中的有益材料分离于有害材料的装置或手段来循环。有益于伤口愈合的材料被再次循环通过伤口包敷物,而有害于伤口愈合的材料被弃置于废物收集袋或器皿。
在国际专利申请WO 2005/04670中,描述了使用吸液、冲洗和清洁伤口来清洁伤口的装置、伤口包敷物和方法。仍以非常概括的方式来说,在此文献中描述的发明采用在吸液、冲洗和清洁伤口方面与WO 2004/037334类似的装置,不过,其进一步包括另外的重要步骤:提供加热装置控制返回到伤口部位/包敷物的有益材料的温度,从而使其处于最优温度,从而例如对伤口具有最有效的治疗效果。
在国际专利申请WO 2005/105180中,描述了用于吸液、冲洗和清洁伤口的装置和方法。仍非常概括的方式来说,此文献描述了与前文中提及的两篇文献类似的装置,不过其具有另外的步骤:提供用于将生理活性剂供应和施加于伤口部位/包敷物以促使伤口愈合的装置。
在此通过引用将上述参考文献的内容并入本文。
不过,前述装置和方法一般仅适用于就医患者,这是因为,所用装置复杂并且需要具有关于如何操作和维护所述装置的专业知识的人员,而且还相对较沉且笨重,不适于例如在医院环境之外由患者进行轻松移动。
一些具有相对较严重伤口的患者例如不需要连续就医,但其会得益于施加更长的TNP治疗,这样的患者可在家中或工作场所治疗,因此需要易于携带和维护的TNP治疗装置。对此,GB-A-2 307 180描述了一种便携式TNP治疗单元,其可由患者携带并夹到腰带或吊带上。因而可将负压施加于伤口部位。
在TNP治疗过程中,便携式或非便携式治疗单元在伤口部位产生负压。当包括空气以及伤口渗出物材料的流体从伤口部位被移除时,流体必须以某些方式在远离伤口部位处被收集。在当前已知的治疗单元中,通常通过连接到治疗单元泵单元的废物罐执行伤口渗出物材料的收集和储存。不过,使用罐可导致治疗单元装置自身相当笨重且制造成本昂贵。而且,更换其中收集有伤口渗出物的罐或罐中的袋可为费时且相对较不卫生的过程。
当前已知的治疗单元还常常包括用于产生负压的泵。这样的泵可能制造成本高且相对较沉。
WO 2007/030601(在此通过引用将其并入本文)公开了具有微量泵的自备式伤口包敷物。用于将伤口流体抽吸到真空区中的泵被包括在伤口包敷物自身中。不过,来自包敷物的伤口渗出物仅可通过复杂的一系列步骤被移除。渗出物移除过程也易于污染,这是因为,一旦吸收层对伤口渗出物完全饱和,则必须开启伤口包敷物中的通路门,使得吸收层和微量泵可移除。应认识到,这样的渗出物移除和泵移除可能是费时的,并可导致各用户之间的交叉感染。进一步的问题在于,伤口包敷物易于过度膨胀和破裂。
发明内容
本发明的一个目的在于至少部分地缓解上述问题。
本发明某些实施例的一个目的在于,提供一种用于在伤口部位提供负压以协助伤口闭合和愈合的方法,其中在治疗过程中从伤口部位抽吸的伤口渗出物被收集和储存在伤口包敷物中。
本发明某些实施例的一个目的在于,提供一种伤口包敷物,其能够设置在伤口部位上并包括用于在伤口部位产生负压的集成泵。而且伤口包敷物可收集任何伤口渗出物。
根据本发明的第一方案,提供用于包敷伤口的装置,包括:
密封层,其包括至少一个孔口;
吸收层,其在所述密封层上,用于吸收伤口渗出物;和
液体不可透过且气体可透过的过滤层,其在所述吸收层上。
根据本发明的第二方案,提供一种在伤口部位施加身体局部负压的方法,包括以下步骤:
通过泵元件从伤口部位泵送伤口渗出物和空气,所述伤口部位附近的周边区域通过伤口包敷物的密封层被密封;
通过所述密封层中的至少一个孔口在所述伤口包敷物吸收层中收集从所述伤口部位泵送的伤口渗出物;和
通过在所述吸收层与延伸在所述伤口包敷物上的覆盖层之间的过滤层从所述伤口包敷物排放气体。
本发明的某些实施例提供以下优点:一次性的伤口包敷物可固定在伤口部位上,并可同时用于在伤口部位提供负压以及收集和储存伤口渗出物。伤口包敷物过滤层允许当集成泵或远程泵在伤口部位产生负压时从伤口包敷物连续排放空气。这防止过度膨胀的风险。
本发明的某些实施例提供以下优点:不需要分立的治疗单元在伤口部位产生负压并收集和储存任何伤口渗出物。而是,伤口包敷物可执行泵送过程和伤口渗出物收集过程。伤口包敷物于是可为单次使用物品,其可没有后续使用。这减少了感染风险。
本发明的某些实施例提供以下优点:伤口包敷物可用于收集在负压治疗过程中产生的伤口渗出物。远离伤口包敷物的泵可被连接到伤口包敷物并重新使用,而伤口包敷物自身用于收集伤口渗出物并且随后可在使用后被弃置。
附图说明
现在将在下文中仅通过示例参照附图描述本发明的实施例,其中:
图1例示出了伤口包敷物;
图2例示出了伤口包敷物的俯视图;
图3例示出了伤口包敷物的一部分;和
图4例示出了具有外部泵的伤口包敷物。
在附图中,相同的附图标记标示相同的部分。
具体实施方式
图1例示出通过根据本发明实施例的伤口包敷物100的截面图。伤口包敷物100的俯视图例示在图2中,其中线A-A指示出图1中所示截面的位置。应理解,图1例示出装置100的概括示意图。应理解,本发明的实施例通常可用于身体局部负压(TNP)系统。简言之,通过减少组织水肿、促进血液流动和微粒组织形成、移除过量渗出物和减少细菌增长(以及感染风险),负压伤口治疗有助于许多形式的“难愈”伤口闭合和愈合。此外,所述治疗使伤口干扰减小,从而使愈合更快。
伤口包敷物100可位于将被处理的伤口部位上。包敷物100形成处于伤口部位上的密封腔。可选地,伤口包封材料可用于伤口腔内并处于包敷物下。适合地,包封材料可为纱布或网状PU泡沫材料。
可以想到,体现本发明的装置的负压范围可在约-50mmHg至-200mmHg之间(应注意,这些压力相对于正常周围大气压而言,因而-200mmHg在实际上将约为560mmHg)。适合地,压力范围可约在-75mmHg至-150mmHg之间。可替代地,可用压力范围可高达-75mmHg、高达-80mmHg或-80mmHg以上。而且,适合地,可使用低于-75mmHg的压力范围。可替代地,可使用的压力范围可高于-100mmHg或高于-150mmHg。
如图1中所示,伤口包敷物100的下表面101可选地设置有伤口接触层102。伤口接触层102可为穿孔的聚氨酯层或聚乙烯层或者其它柔性层,并例如通过热钉工艺或一些其它方式穿孔,或者可制成为使液体和气体可透过。伤口接触层具有下表面101和上表面103。穿孔104为伤口接触层中的通孔,其使流体能够流动通过所述层。伤口接触层有助于防止组织向内生长至伤口包敷物的其它材料中。穿孔足够小以满足这一要求但仍允许流体通过。伤口接触层还有助于将整个伤口包敷物保持在一起并用作可选的上、下粘接层(未示出)的载体。例如,下压敏粘接层可设置在伤口包敷物的下侧表面101上,而上压敏粘接层可设置在伤口接触层的上表面103上。压敏粘接剂可为硅酮或丙烯酸类的粘接剂或其他这样的粘接剂,并可形成在伤口接触层的两侧上或者可选地形成在伤口接触层的所选侧上或不形成在伤口接触层的侧上。当采用下压敏粘接层时,这有助于伤口包敷物粘接到伤口部位附近的皮肤。
多孔材料层105,例如泡沫层或类似物,可位于伤口接触层之上。这种多孔层允许将包括液体和气体的流体传送离开伤口部位而至伤口包敷物的上层中。层105还有助于分配由泵产生的压力(如下文中更详细所述),使得整个伤口部位承受均衡的负压。天然或合成的网状泡沫或非编织材料可用作多孔层105的多孔材料。
使气体不可透过的密封层106延伸越过伤口包敷物的宽度。密封层(其例如可为在两侧上具有压敏粘接剂的聚氨酯膜)使气体不可透过,因而该层操作以密封伤口腔(伤口包敷物设置在其上)。以这种方式,有效室形成在密封层之下并处于密封层与可建立负压的伤口部位之间。适合地,虽然密封层使气体不可透过,不过密封层的材料可具有高的湿气可透性。例如,由BASF制造的Elastollan(商标名称)SP9109。可选地,点图样分散丙烯酸粘接剂可用于协助改进湿气可透性。使用高湿气可透性材料作为密封层160的优点在于,通过使湿气散发透过所述膜并散到大气中的行为,包敷物的流体处理能力可显著增大。有利地,由于在包敷时实现的高湿度和在以大气压之下高达250mmHg的负压使用所述装置的过程中实现的材料紧密接触,因而散发速率可易于实现3000g/cm2/24小时的量。
如图1中所示,单一的中心孔口设置在密封层中。应认识到,作为可替代方式,单一孔口107可被设置为多个通孔。孔口107使得集成到伤口包敷物的与阀(未示出)相关联的微量泵110能够将流体从密封层106之下的区域吸到密封层106之上的区域中。泵的入口以与孔口107面对的方式定位,而泵110的出口121被布置以排放利用泵被泵送到吸收材料层130的流体。吸收材料可为泡沫或非编织的天然或合成的材料,并可选地可包括或可为超级吸收材料,且形成从伤口部位移除的流体(特别是液体)的蓄积部。吸收材料层还防止在伤口包敷物中所收集的液体以晃动方式流动。吸收层130还有助于通过毛细作用在整个所述层上分配流体,使得流体从泵排放出口121近处的区域中被抽吸到更远的区域中,从而避免在泵出口附近发生凝聚。
过滤层140被设置在吸收层130上。用于过滤层140的过滤材料的适合材料是在MMT范围内的0.2微米GoreTM膨胀PTFE。也可使用更大的孔尺寸,不过这样可能需要次级过滤层以确保完全封闭生物载荷。当伤口流体包含油脂时,优选地但并非必需地,使用疏油过滤膜,例如,在0.2微米MMT-323之前的1.0微米MMT-332。这防止油脂阻挡疏水过滤物。
应理解,其它类型的材料可用于过滤层。更常见地,可使用微孔膜,其为聚合物材料的平坦薄片且包含数十亿个微观孔。根据所选的膜,这些孔的尺寸范围可从0.01微米至大于10微米。微孔膜在亲水(透水)和疏水(斥水)形式中均可用。适合地,根据本发明特定实施例的伤口包敷物100使用微孔疏水膜(MHM)。例如,PTFE,聚丙烯,PVDF,和丙烯酸共聚物。所有这些可选聚合物可被处理以获得可疏水和疏油的具体表面特性。这样,这些膜将排斥具有低表面张力的液体,例如,多维生素浸剂,油脂,表面活性剂,油,和有机溶剂。
MHM阻挡液体,而同时允许空气流动通过膜。这些膜也是高效空气过滤器,消除了可能具有传染性的浮质和颗粒。单件的MHM公知为替代机械阀或泄放孔的可选物。这样,包括MHM,可降低产品组装成本以提高利润,并对患者而言提高了性价比。
过滤层140因而使气体能够向上排放通过伤口包敷物。不过,液体、微粒和病原体包含在包敷物中。
覆盖层150覆盖伤口包敷物100的吸收层。覆盖层例如可为聚氨酯膜,其用作抗菌层并且有助于有效阻止液体腐坏。覆盖层密封于过滤层。例如通过粘接或焊接技术密封。这样,离开包敷物的气体通过过滤层并之后通过覆盖层中的孔151。覆盖层还为包敷物提供整体性,并利用设置在覆盖层中的通孔151(例如利用穿孔阵列)使湿气和气体可透过。这些有助于改进对通过伤口包敷物的湿气和气体的可透性。在可替代实施例中,过滤层140可替代地可覆盖由密封层106密封的整个包敷物。可包括保护层或增强层(其可为非编织的或穿孔的膜)。适合地,覆盖层150由具有高湿气可透性的材料制成。例如,由BASF制造的Elastollan(商标名称)SP9109。可选地,点图样分散丙烯酸粘接剂可用于协助改进湿气可透性。使用高湿气可透性材料作为密封层160的优点在于,通过使湿气散发透过所述膜并散到大气中的行为,包敷物的流体处理能力可显著增大。有利地,由于在包敷时实现的高湿度和在以大气压之下高达250mmHg的负压使用所述装置的过程中实现的材料紧密接触,因而散发速率可易于实现3000g/cm2/24小时的量。
转到图2,其中例示出根据本发明实施例的伤口包敷物100,其中可见,覆盖层150的上表面沿径向向外延伸远离包敷物的中心而至围绕叠盖于吸收层130的中心隆起区域201的边界区域200中。图2还有助于例示在覆盖层中形成的穿孔151的阵列。
图3例示出图1和2中所示伤口包敷物100的边界区域200的详细图。如图可见,覆盖层150在吸收层130上延伸至边缘区域中。在此,覆盖层固定到密封层106和伤口接触层102。图3还有助于例示伤口接触层102中的穿孔104如何沿泡沫层105延伸。
应理解,根据本发明的实施例,伤口接触层是可选的。该层在使用时可透水并面向下面的伤口部位。下多孔层105,例如网状PU泡沫层,用于分配对气体和流体的移除,使得所有伤口面积均承受相等压力。密封层在伤口上形成大致密闭的密封。这样,在密封层之下产生由泵110泵送的负压。此负压因而施加在目标伤口部位处。包括空气和伤口渗出物的流体被抽吸通过伤口接触层和网状表面层、通过孔口107并进入泵110处的流体入口120。泵通过流体出口121排放流体,在流体出口121处,液态组分通过毛细作用离开而被收集和储存在整个吸收层130上。被排放流体的气态组分与一些湿气一起通过过滤层并通过覆盖层穿孔被排放。过滤层确保病原体和不佳气味不会离开由吸收层形成的蓄积区域。
本领域技术人员应认识到,如果不是使覆盖层叠盖过滤层,则覆盖层自身可被过滤层叠盖。因此,覆盖层可为伤口包敷物的最外层,或者过滤层可为伤口包敷物的最外层。进一步地,可选地,可使用外层(未示出),只要其使气体和水汽可透过即可。
更进一步,可选地,包敷物可包含抗菌物,例如在伤口接触层上的纳米晶银剂和/或在吸收层中的磺胺银。这些抗菌物可单独使用或一起使用。这些抗菌物分别杀灭伤口中的微生物和吸收基质中的微生物。更进一步,可选地,可包括其它活性组分,例如止痛剂,如布洛芬。而且,可使用增强细胞活性的药剂(例如生长素)或抑制酶活性的药剂(例如基质金属蛋白酶抑制剂,如金属蛋白酶组织抑制剂(TIMPS)或锌螯合剂)。更进一步,可选地,气味吸收元件(例如活性碳、环糊精、沸石、或类似物)可包括在吸收层中或作为过滤层之上的又一层。
图4例示出本发明的可替代实施例,其中,泵未集成设置在伤口包敷物400内。而是,连接管401连接到密封层中的孔口107。出口管401沿其外周界密封于覆盖层150和过滤层140。出口管401连接到远程泵,远程泵可与伤口包敷物400分开一定距离或可安装到伤口包敷物的边界。远程泵的出口固定到入口管402,入口管402沿其周界密封于通向开口403的覆盖层150。以这种方式,当泵操作以将负压施加于密封层106之下的区域时,通过伤口接触层102和下流体分配层105、通过孔口107、并且沿出口管401抽吸渗出物。包括空气和伤口渗出物的流体通过泵,并在出口管402中的开口403的近处区域中被排放。流体的液态部分通过毛细作用离开而被收集在吸收层130的主体中。空气和湿气通过过滤层,并通过覆盖层中的孔而进入周围大气中。
应理解,根据本发明的实施例,当从伤口部位抽吸流体时,吸收层可能膨胀。这可使得过滤层和覆盖层的上表面显得略微鼓起。在许多方面,鼓起可用作视觉提示以指示何时应更换伤口包敷物。
如前文中参照图4中所示实施例所述,远程泵可安装到伤口包敷物的边界,在这种情况下,管401、402可直接连接到泵。随后,单次使用伤口包敷物,因而可略去泵。可选地,管可设置有插配(clickfit)连接器或其它易装配连接器,所述连接器可连接到对应的配合连接器,且配合连接器通过对应的管接合到远程泵。以这种方式,远程泵可重新使用,而包括连接管和连接器的伤口包敷物自身在单次使用之后可被弃置。
应理解,对于包括安装在覆盖层上或包敷物周边边界区域上的泵的本发明实施例而言,可包括集成动力源和控制电路。可替代地,动力源可在泵外并被远程安装。远程动力源和/或控制电路改进了包敷物的一次性,并允许在使用备用电池时对电池再充电。
应认识到,包敷物在使用中能够以一角度或竖直地“颠倒”使用。因此,上、下基准仅用于阐释目的。
应认识到,可替代地,管401、402可以是单一的双腔管。在又一可替代方案中,管401、402可替代地可以是单一的连续环形管,所述管然后穿过蠕动泵的夹送滚轮。
在本申请文件的说明书和权利要求书的全文中,用词“包括”和“包含”及其变形(例如用作现在分词的“包括”和谓语动词的“包括”)意味着“包括但不限于”,其并无意(而且并不)排除其它部分、添加物、组分、完整物、或步骤。
在本申请文件的说明书和权利要求书的全文中,单个涵盖多个,除非在应用环境中另有要求。特别地,当使用不确定的表述时,其限定应被理解为包括多个以及单个,除非在应用环境中另有要求。
结合本发明的具体方案、实施例或示例描述的特征、整体、特性、化合物、化学分子结构的部分或基团,应被理解为可用于任何在此描述的其它方案、实施例或示例,除非相互不相容。

Claims (30)

1.一种用于包敷伤口的装置,包括:
密封层,所述密封层包括至少一个孔口;
吸收层,所述吸收层处于所述密封层上,用于吸收伤口渗出物;和
液体不可透过但气体可透过的过滤层,所述过滤层处于所述吸收层上。
2.如权利要求1所述的装置,进一步包括:
所述密封层对于在远离每个孔口的各区域中流动经过的流体基本上不可透过。
3.如权利要求1或2所述的装置,其中,所述密封层被布置为在将身体局部负压TNP施加于伤口部位处之前密封所述伤口部位。
4.如前述任一权利要求所述的装置,其中,所述吸收层被布置成吸收穿过所述孔口的伤口渗出物。
5.如前述任一权利要求所述的装置,其中,所述过滤层处于所述吸收层与叠置覆盖层之间。
6.如权利要求5所述的装置,进一步包括:
泵元件,其位于所述覆盖层与所述密封层之间,并包括与所述密封层的孔口流体连通的入口和与所述吸收层流体连通的出口。
7.如权利要求5所述的装置,进一步包括:
抽取管状导管,其与所述密封层的至少一个孔口流体连通,并以密封方式延伸穿过所述过滤层和/或覆盖层。
8.如权利要求5、6、7中任一项所述的装置,进一步包括:
入口管状导管,其与所述吸收层流体连通,并以密封方式延伸穿过所述过滤层和/或覆盖层。
9.如权利要求7或8所述的装置,进一步包括:
所述抽取管状导管和/或入口管状导管能够连接到远程泵元件。
10.如前述任意权利要求所述的装置,进一步包括:
伤口接触层。
11.如权利要求10所述的装置,进一步包括:
粘接层,其处于所述伤口接触层的上侧和/或下侧上。
12.如权利要求10或11所述的装置,其中,所述伤口接触层是穿孔的聚氨酯或聚乙烯层。
13.如前述任一权利要求所述的装置,进一步包括:
多孔层,其处于所述伤口接触层与所述密封层之间。
14.如权利要求10所述的装置,进一步包括:
可移除的保护层,其处于所述伤口接触层的下表面上。
15.如权利要求5至14中任一项所述的装置,进一步包括:
所述密封层和覆盖层从所述吸收层的边缘区域径向向外延伸,由此形成周边边界区域,所述密封层和覆盖层在所述边界区域中被密封在一起。
16.如权利要求15从属于权利要求10时所述的装置,其中,所述伤口接触层与所述密封层和覆盖层在所述边界区域中密封在一起。
17.如权利要求15或16所述的装置,进一步包括:
泵元件,其固定到所述周边唇缘区域,并能够通过抽取管状导管连接到所述密封层中的至少一个孔口且能够通过入口管状导管连接到所述吸收层。
18.如前述任一权利要求所述的装置,进一步包括:
抗菌剂,其处于伤口接触层中和/或处于所述吸收层中。
19.如前述任一权利要求所述的装置,进一步包括:
镇痛剂和/或细胞活性增强剂。
20.如前述任一权利要求所述的装置,其中,所述覆盖层处于所述过滤层上,或者,所述过滤层处于所述覆盖层上。
21.如前述任一权利要求所述的装置,进一步包括气味吸收元件。
22.一种将身体局部负压施加于伤口部位的方法,包括以下步骤:
通过泵元件从伤口部位泵取伤口渗出物和空气,所述伤口部位附近的周边区域通过伤口包敷物的密封层密封;
通过所述密封层中的至少一个孔口在所述伤口包敷物吸收层中收集从所述伤口部位泵送的伤口渗出物;和
通过在所述吸收层之上的过滤层从所述伤口包敷物排放气体。
23.如权利要求22所述的方法,进一步包括以下步骤:
通过位于所述吸收层与延伸在所述伤口包敷物上的覆盖层之间的所述过滤层排放气体。
24.如权利要求22所述的方法,进一步包括以下步骤:
通过位于延伸在所述伤口包敷物上的覆盖层上的所述过滤层排放气体。
25.如权利要求22、23或24所述的方法,进一步包括以下步骤:
通过所述伤口包敷物的集成泵元件来泵送伤口渗出物和空气,其中所述集成泵元件与所述吸收层和所述密封层的至少一个孔口流体连通。
26.如权利要求22所述的方法,进一步包括以下步骤:
通过远程泵元件来泵送伤口渗出物和空气,其中所述远程泵元件与所述吸收层和所述密封层的至少一个孔口流体连通。
27.如权利要求22至26中任一项所述的方法,进一步包括以下步骤:
通过在所述密封层与所述包敷物的伤口接触层之间的多孔层分配由所述泵元件产生的负压。
28.如权利要求22至27中任一项所述的方法,进一步包括以下步骤:
通过使渗出物利用毛细作用离开被泵送流体的排出区域而至远离所述排出区域的所述吸收层的区域中,分配在所述吸收层中收集的渗出物。
29.一种基本如本文参照附图所作描述构建和布置的装置。
30.一种基本如本文参照附图所描述的方法。
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CN107320791A (zh) * 2012-03-12 2017-11-07 史密夫及内修公开有限公司 用于减压伤口治疗的伤口敷料装置
CN107320791B (zh) * 2012-03-12 2022-02-08 史密夫及内修公开有限公司 用于减压伤口治疗的伤口敷料装置
CN105338933A (zh) * 2013-06-18 2016-02-17 莫恩里克保健股份公司 流体输送敷料
CN104117131A (zh) * 2014-07-22 2014-10-29 翁跃勤 一种负压切口愈合器及方法
CN113367890A (zh) * 2015-04-27 2021-09-10 史密夫及内修公开有限公司 减压装置
CN113367890B (zh) * 2015-04-27 2023-02-21 史密夫及内修公开有限公司 减压装置

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