CN102090893A - Portable sleep apnoea hypoventilation detector - Google Patents

Portable sleep apnoea hypoventilation detector Download PDF

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Publication number
CN102090893A
CN102090893A CN2011100527853A CN201110052785A CN102090893A CN 102090893 A CN102090893 A CN 102090893A CN 2011100527853 A CN2011100527853 A CN 2011100527853A CN 201110052785 A CN201110052785 A CN 201110052785A CN 102090893 A CN102090893 A CN 102090893A
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module
microprocessor
links
detector
sleep apnea
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CN2011100527853A
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Chinese (zh)
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陈真诚
朱健铭
胡寒冬
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Guilin University of Electronic Technology
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Guilin University of Electronic Technology
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Priority to CN2011100527853A priority Critical patent/CN102090893A/en
Publication of CN102090893A publication Critical patent/CN102090893A/en
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Abstract

The invention discloses a portable sleep apnoea hypoventilation detector which comprises a microprocessing system, a light-emitting driving module, a light emitter, a light receiver, a pressure sensor, a digital display module, a storage module, a clock module, a USB communication module, a pressure-regulation module, a lithium battery charge module and a lithium battery. System tests indicate that the detector can be used for effectively extracting pulse waves and breathing signals, figuring out pulse frequency and oxyhemoglobin saturation and estimating the sleep condition of people by combining with the breathing signals. Meanwhile, because the portable sleep apnoea hypoventilation detector is small and portable, and is simple in operation, is especially suitable for family or individuals, and is also suitable for the initial diagnosis of health mechanisms, such as hospitals and the like, to the sleep conditions of patients.

Description

The low ventilation of a kind of portable sleep apnea detector
Technical field
The present invention relates to the low ventilation of a kind of portable sleep apnea detector, belong to medical electric diagnostic instruments technical field.
Background technology
Sleep is the rest mode that human body regains one's vigor best, and good sleep helps improving people's quality of life and work efficiency.Current, behind the monitoring index of sleep quality as an important physiological function, the sleep-respiratory disease begins to obtain people's growing interest and attention.
In numerous respiratory disorders, sleep apnea syndrome is exactly a kind of disease common in the respiratory disorder.Sleep apnea syndrome be make for some reason on when sleep that airway pressure is smooth or stop up and cause that asphyxia and low ventilation, The main symptoms have that blood oxygen saturation is on the low side, snoring, daytime is drowsiness etc.Medically point out: sleep apnea syndrome is meant in sleep at the night process and asphyxia takes place and low ventilation shows effect more than 30 times repeatedly that perhaps the sleep apnea low index is more than or equal to 5 times/hour.Wherein, sleep apnea is meant that the mouth and nose respiratory air flow all stopped more than 10 seconds in the sleep procedure, and low ventilation is meant that the decline of sleep-respiratory air-flow descends more than or equal to 4% more than 50% and with blood oxygen saturation.
Though traditional asphyxia monitor system can reduce asphyxia patient's mortality rate effectively, but can't satisfy most asphyxia patient's real-time monitoring requirement, particularly slight apnea syndrome early stage patient, except the random thoughts hypopnea, there is not symptom at ordinary times, generally also only continued for tens seconds, do when breathe checking Deng arriving in hospital, because transference cure, breathe and recover normal, the doctor can not in time be made a definite diagnosis patient, and disease also is difficult to obtain early treatment and control.Therefore, the dynamic breathing record in can the long active procedure of record analysis patient, and it is analyzed, provide data to the doctor with diagnostic value, for the assessment of respiratory function, the early diagnosis of sleep apnea disease is highly profitable.Needs at this medical diagnosis, along with developing rapidly of computer technology and electronic technology, in the last few years, the Active sleep asphyxia record and the analytical system of different class have been released on the market, and this quasi-instrument costs an arm and a leg and need substantially from external import, and inconvenience is promoted the use of among hospital and the patient at home.So design a kind of low-power consumption, little, the low-cost sleep-respiratory monitor of volume is very necessary.
Summary of the invention
The invention provides that a kind of low-power consumption, volume are little, low price, be fit to family or the individual uses, be applicable to that also health organ such as hospital does the low ventilation of the portable sleep apnea detector of the diagnosis at initial stage to patient's sleep situation.
The technical solution adopted in the present invention is: comprising with the microprocessor is the control core circuit, with and each peripheral module circuit.Concrete connected mode is: microprocessor links to each other with the light emission driver module, and the light emission driver module links to each other with light-emitting tube, and the work process of this partial circuit is that microprocessor is lighted optical transmitting set through the optical drive module; Microprocessor links to each other with light receiving tube, light receiving tube is received optical signal be converted to the signal of telecommunication and send into microprocessor processes; Microprocessor links to each other with pressure transducer, and the breath signal that pressure transducer is received is sent into the microprocessor processing; Microprocessor links to each other with memory module, the storage of each data when realizing test; Microprocessor links to each other with clock module, to realize test real time record constantly; Microprocessor links to each other with the usb communication module, handles so that the data of test are delivered to PC; Microprocessor links to each other with digital display module, to realize the demonstration to the result of test; Voltage regulating module links to each other with microprocessor, respiration pickup, digital display module, memory module, clock module, for each module provides required voltage; Lithium battery links to each other with voltage regulating module, for whole system provides the energy.The lithium cell charging module links to each other with lithium battery, links to each other with microprocessor again simultaneously, realize microprocessor to battery intelligent charge control.
Work process of the present invention is: this detector refers to press from both sides the transmission-type blood oxygen probe by NELLCOR and associated driver circuitry is gathered human pulse ripple signal; Extract the nasal respiration pressure signal by the HONEYWELL pressure transducer; Shown the oximetry value and the pulse frequency value of current time in the process of test by character display real-time dynamicly, the amplitude of oximetry value, pulse frequency value and breath signal can have been deposited in the data storage simultaneously; On software design, adopt Visual C++ as development platform, designed and Implemented the PC end software system supporting with tester.The physiological data of being deposited when detector will be tested by the USB line all is uploaded to PC, and the software kit of PC end is added up these data and is depicted as curve so that the manual analysis breath state.Simultaneously, the Algorithm Analysis that this software kit can be by strictness with handle after provide the testee and have to breathe no more and suspend or the test result of low pass gas.
Characteristic of the present invention is:
1. volume is small and exquisite, low in energy consumption, but follow-on test reaches 10 hours, and has disposed lithium battery power supply, the use of can charging repeatedly.
2. using method is simple.Only need blood oxygen probe is clipped on the finger, and the nose conduit shouted with nose link to each other, one gets final product proper testing by switch.
3. there is not wound.Detection method by the light transmission-type replaces traditional detection method that wound or Wicresoft are arranged to detect blood oxygen saturation, and the fear of having eliminated the testee is with painful.
4. highly sensitive, high-precision respiration detection.Used HONEYWELL pressure transducer, the differential pressure of perception delicately ± 15mm Hg (with respect to the atmospheric pressure of environment of living in), the precision of test reaches 0.2%, can accurately measure the variation of human body respiration air-flow.
Disposed supporting PC end data process software.Data upload is to PC end process software, and this process software can show the number of times of asphyxia or low pass gas and the moment of generation exactly, provides reliable foundation to the analysis of testee's breath state.
Figure of description
The functional block diagram of this instrument of Fig. 1
Fig. 2 nose conduit connection diagram
Fig. 3 microcontroller circuit figure
Fig. 4 light emission driver module
Fig. 5 receives amplification module
Fig. 6 pressure sensor module
Fig. 7 clock chip module
Fig. 8 memory module
Fig. 9 usb communication module
Figure 10 regulating circuit module
Figure 11 battery charging module
Concrete implementation process
This instrumental function structured flowchart as shown in Figure 1, comprising with the microprocessor is the control core circuit, with and each peripheral module circuit.The connected mode of each peripheral module is: microprocessor links to each other with the light emission driver, and the light emission driver links to each other with photoemission cell, and the work process of this partial circuit is that processor is lighted optical transmitting set through CD-ROM driver; Microprocessor links to each other with light receiving tube, light receiving tube is received optical signal be converted to the signal of telecommunication and send into microprocessor processes; Microprocessor links to each other with pressure transducer, and the breath signal that pressure transducer is received is sent into the microprocessor processing; Microprocessor links to each other with memorizer, the storage of each data when realizing test; Microprocessor links to each other with the timing chip, to realize test real time record constantly; Microprocessor links to each other with the USB transmission circuit, handles so that the data of test are delivered to PC; Microprocessor links to each other with character display, to realize the demonstration of test result; Regulating circuit links to each other with microprocessor, respiration pickup, character display, memorizer, clock module, for each module provides required voltage; Lithium battery links to each other with regulating circuit, for whole system provides the energy.The lithium cell charging circuit links to each other with lithium battery, links to each other with microprocessor again simultaneously, realize microprocessor to battery intelligent charge control.
Nose conduit connection diagram as shown in Figure 2, native system is gathered the respiratory pressure signal by the nose conduit, and the nose conduit is drawn direct the shouting with two noses of people in back from this instrument and is linked to each other.
Microcontroller circuit figure as shown in Figure 3, it is the core of this instrument, all peripheral modules are all by its control.
Light emission driver module as shown in Figure 4, this drive circuit is based on photoelectricity volume law theory, need two alternative flickers of transmitting tube of Single-chip Controlling, gather the photoelectricity pulse wave by the signal of photoelectric receiving tube, P22 and P23 connect the P2.2 and the P2.3 foot of microprocessor respectively among the figure, control also selects the periodicity of two light emitting diodes to glimmer, DAC0_0 and DAC0_1 connect 10 feet and 5 feet of single-chip microcomputer respectively, output as single-chip microcomputer DAC, the control driving voltage, regulate the brightness of light emitting diode, 2 feet of DB9 mouth and 3 feet are respectively the positive pole of red diodes and the positive pole of infrared diode; The operation principle of this drive circuit is: when P22 is a low level, when P23 is high level, NPN type audion Q500 conducting, NPN type audion Q501 ends, and DAC0_0 output this moment high level makes the Q503 conducting, so, just formed the conductive channel of being made up of Q500 and Q503, made the red diodes conducting, infrared diode oppositely ends; In like manner, when P22 is a high level, when P23 is low level, the Q501 conducting, Q500 ends, and DAC0_1 exports high level, makes the Q502 conducting to have formed the conductive channel of being made up of Q501 and Q502, makes the near infrared diode conducting, and red diodes is oppositely ended.
Reception amplification module as shown in Figure 5, the amplifying unit of this module is integrated in microprocessor internal, in this Module Design, form current/voltage (I/V) change-over circuit by operational amplifier U1B and photoelectric receiving tube, wherein photoelectric receiving tube adopts the photovoltaic mode of operation, guarantee that it is operated in the range of linearity, reduced the dark current noise that photoelectric receiving tube brings like this; After photoelectric receiving tube receives photosignal, produce photo-signal, be converted into voltage signal through R3, amplify back output through operational amplifier U1 again, the signal of output has just obtained required photoelectricity pulse wave signal by the collection of ADC module.
Pressure sensor module as shown in Figure 6 mainly is to gather breath signal by pressure transducer, and this pressure transducer inside carries signal conditioning circuit, and through behind the signal conditioning circuit, the ADC that sends into microprocessor handles for microprocessor.
Clock chip module as shown in Figure 7, record for convenience of subscriber signal, need be to the time record of being correlated with of test, comprising exact date of detecting and concrete time of detection, and this will finish the record of detection time by means of clock chip, select DS1302 as clock chip herein, communicate by letter between DS1302 and the single-chip microcomputer and only need use three lines (RST resets, I/O data wire, SCL serial clock) and just can communicate.
Memory module as shown in Figure 8, as portable product, when data are gathered, relevant initial data should be preserved, analyze and handle so that call next time, so native system has externally been expanded a Flash memorizer M25P64, the size of its memory space is 64M, this memorizer is mainly used in the physiological signal of storage of collected, with to be transmitted to PC.
Usb communication module as shown in Figure 9, because what whole system adopted is the duplex architecture of upper and lower machine, this just requires to carry out between the upper and lower computer transmission of related data and instruction, factors such as transfer rate in conjunction with interface, native system has selected USB to communicate, the CH372 that selects main flow is as interface chip, and its periphery comprises the crystal oscillator of 12M, and the interface mode of communicating by letter with PC is the MiniUSB interface of 5 pins.
Regulating circuit module as shown in figure 10, this instrument is a portable medical device, so volume, weight and low-power consumption characteristic to power supply have certain requirement, select TPS76733 output 3.3V to power at this to single-chip microcomputer, select LTC3203 output 5V to power to respiration pickup.
Battery charging module as shown in figure 11, consider the diseconomy of using common No. 5 or No. 7 batteries, what this instrument adopted is the rechargeable lithium battary power supply, and the acp chip of lithium cell charging circuit is MAX1898, and its periphery is connected to LED to show whether charging is finished; After finishing charging, microprocessor can stop automatically to battery charge, with anti-overcharge damage battery.
To sum up, the present invention relates to the low ventilation of a kind of portable sleep apnea detector, is design and develop at the demand of sleep apnea disease early diagnosis clinically a kind of portable, low-power consumption, low-cost sleep-respiratory monitor.This monitor is mainly gathered blood oxygen saturation, pulse frequency and the mouth and nose breath signal of human body, definition according to the diagnosis of sleep apnea hypoventilation syndrome, according to its assessment of breathing the decline index and coming sleep apnea hypoventilation syndrome patient is made its sleep state, provide corresponding test result in conjunction with the variation of pulse frequency and oxygen saturation signal.

Claims (11)

1. the low ventilation of a portable sleep apnea detector is made up of microprocessing systems, light emission driver module, optical transmitting set, optical receiver, pressure transducer, digital display module, memory module, clock module, usb communication module, voltage regulating module, lithium cell charging module and lithium battery; It is characterized in that: microprocessor (1) links to each other with light emission driver module (2), and light emission driver module (2) links to each other with optical transmitting set (3), and the work process of this partial circuit is that processor (1) is lighted optical transmitting set (3) through optical drive module (2); Microprocessor (1) links to each other with photelectric receiver (4), optical receiver (4) is received optical signal be converted to the signal of telecommunication and send into microprocessor (1) and handle; Microprocessor (1) links to each other with pressure transducer (9), and the breath signal that pressure transducer (9) is received is sent into microprocessor (1) processing; Microprocessor (1) links to each other with memory module (5), the storage of each data when realizing test; Microprocessor (1) links to each other with clock module (8), to realize test real time record constantly; Microprocessor (1) links to each other with usb communication module (7), so that the data of test are delivered to monitoring software (14) processing of PC; Microprocessor (1) links to each other with digital display module (6), to realize the demonstration to the result of test; Voltage regulating module (10) links to each other with microprocessor (1), pressure transducer (9), digital display module (6), memory module (5), clock module (8), for each module provides required voltage; Lithium battery (13) links to each other with voltage regulating module (10), for whole system provides the energy; Lithium cell charging module (11) links to each other with lithium battery (13), links to each other with microprocessor (1) again simultaneously, realizes the intelligent charge control of microprocessor (1) to lithium battery (13).
2. portable sleep apnea low pass gas detector according to claim 1, it is characterized in that: described microprocessor (1) is made of single-chip microcomputer, MSP430FG437 or MSP430FG439 single-chip microcomputer that concrete model is produced for TI company.
3. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: described optical transmitting set (3) is integrated in one with optical receiver (4), adopt be Nellcor company produce the finger-clipped probe, the interface mode of connection is the DB9 interface.
4. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: the 40PC001B pressure transducer that described pressure transducer (9) is produced for Honeywell company, its output signal links to each other with the AD switched pins of microprocessor (1) through the series resistance dividing potential drop.
5. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: the employed acp chip model of described usb communication module (7) is CH372 or CH375, its periphery comprises the quartz crystal oscillator of 12M, and the interface mode of communicating by letter with PC is the MiniUSB interface of 5 pins.
6. the low ventilation of portable sleep apnea according to claim 1 detector, the chip that described voltage regulating module (10) uses has LTC3203 and TPS76733, it is characterized in that: LTC3203 gives respiration pickup (9) power supply, and TPS76733QD gives microprocessor (1) power supply.
7. the low ventilation of portable sleep apnea according to claim 1 detector, the chip model that described digital display module (6) uses is TPL004, the chip model that described memory module (5) is used is M25P64, it is characterized in that: memory module (5) all directly links to each other with microprocessor (1) with digital display module (6).
8. the low ventilation of portable sleep apnea according to claim 1 detector, the acp chip of described lithium cell charging module (11) is MAX1898, it is characterized in that: its periphery is connected to LED to show whether charging is finished.
9. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: described voltage regulating module (10) divides two pcb boards to arrange with other signal processing module, two parts connect by the winding displacement of 8 pins, to reduce the interference that the simulation part is handled signal section, played the effect that reduces the pcb board area simultaneously.
10. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: the method for described respiration detection adopts the nose conduit that people's nose is shouted with pressure transducer (9) directly to link to each other, and is directly gathered breath data and is deposited in the data storage (5) by microprocessor (1).
11. the low ventilation of portable sleep apnea according to claim 1 detector, it is characterized in that: directly show pulse frequency value and oximetry value by digital display module (8) in the process of test, simultaneously can with the test pulse frequency value, oximetry value, breathing value deposit in the memory module (5), but follow-on test and the storage for up to 10 hours.
CN2011100527853A 2011-03-07 2011-03-07 Portable sleep apnoea hypoventilation detector Pending CN102090893A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283648A (en) * 2011-08-08 2011-12-21 深圳市倍泰健康测量分析技术有限公司 Network type multifunctional human body physiological parameter detector
CN103860151A (en) * 2014-03-12 2014-06-18 郑州雅晨生物科技有限公司 Portable SAHS (Sleep Apnea Hypopnea Syndrome) screening device with automatic analysis function
CN104207754A (en) * 2014-09-19 2014-12-17 苏州经贸职业技术学院 Portable pulse measuring instrument with clock function
CN104382574A (en) * 2014-11-06 2015-03-04 李久朝 Method and system for monitoring sleep quality based on pulse wave data
CN104510479A (en) * 2014-12-12 2015-04-15 天津大学 Blood oxygen acquisition system
CN106204892A (en) * 2016-08-18 2016-12-07 浙江然鹏电子有限公司 A kind of multispectral transmitting and reception device
CN107376077A (en) * 2017-07-28 2017-11-24 惠州市格农科技有限公司 Sleeping method and sleeping equipment
CN110638442A (en) * 2019-10-10 2020-01-03 沃立(常州)医疗科技有限公司 Electrocardio monitoring system and electrocardio monitoring method
CN113288059A (en) * 2021-05-27 2021-08-24 山东大学 Respiration detection device and use method thereof

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283648A (en) * 2011-08-08 2011-12-21 深圳市倍泰健康测量分析技术有限公司 Network type multifunctional human body physiological parameter detector
CN103860151A (en) * 2014-03-12 2014-06-18 郑州雅晨生物科技有限公司 Portable SAHS (Sleep Apnea Hypopnea Syndrome) screening device with automatic analysis function
CN104207754A (en) * 2014-09-19 2014-12-17 苏州经贸职业技术学院 Portable pulse measuring instrument with clock function
CN104382574A (en) * 2014-11-06 2015-03-04 李久朝 Method and system for monitoring sleep quality based on pulse wave data
CN104510479A (en) * 2014-12-12 2015-04-15 天津大学 Blood oxygen acquisition system
CN106204892A (en) * 2016-08-18 2016-12-07 浙江然鹏电子有限公司 A kind of multispectral transmitting and reception device
CN107376077A (en) * 2017-07-28 2017-11-24 惠州市格农科技有限公司 Sleeping method and sleeping equipment
CN110638442A (en) * 2019-10-10 2020-01-03 沃立(常州)医疗科技有限公司 Electrocardio monitoring system and electrocardio monitoring method
CN113288059A (en) * 2021-05-27 2021-08-24 山东大学 Respiration detection device and use method thereof

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Application publication date: 20110615