CN102245136B

CN102245136B - An apparatus for temporary male contraception

Info

Publication number: CN102245136B
Application number: CN200980149808.3A
Authority: CN
Inventors: 彼得·福塞尔
Original assignee: Milutinovic Alex Holdings Ltd
Current assignee: IMPLANTICA PATENTS CO., LTD.
Priority date: 2008-10-10
Filing date: 2009-10-09
Publication date: 2014-12-03
Anticipated expiration: 2029-10-09
Also published as: US11938318B2; CN102245136A; JP2012505021A; AU2009307128C1; JP2022183214A; CA2776506C; EP2346456A1; AU2009307128B2; EP3848008A1; SI2346456T1; BRPI0920348A2; EP3848008B1; ES2960837T3; EP4122432B1; EP4122432C0; CA2776506A1; EP2346456B1; JP2016026104A; JP6166328B2; US20110192402A1

Abstract

The present invention relates to a male contraception apparatus for obtaining temporary sterility of a male mammalian individual. The apparatus comprises an implantable restriction device adapted to restrict vas deference in the region downstream the ampulla during a controlled period in order to preventing sperms to reach the urethra. Further, the apparatus comprises a control device for controlling the operation of the restriction device.

Description

For the apparatus of provisional male contraceptive

Technical field

Generally, the present invention relates to system and apparatus for male contraceptive, the operation of contraception is by deferent duct closure within the controlled interim phase.

Background technology

The conventional route of male contraceptive is the obturation of deferent duct (sperm transfer passage).Vasectomy is vasectomized surgical operation, and is conventionally limited to permanent sterile.Recently, will be inserted into the equipment of deferent duct and acquisition blocking effect by providing, people have had other available selections.U.S. Patent No. 6513528 has been described a kind of such technology, and it relates to one group for inserting deferential silica gel plug.But even if this technology has showed reverse probability, individual fertility is also for example, with some side effect (formation of sperm antibody) relevant.Therefore, need gentleer technology to obtain controlled male contraceptive, it allows with affect minimum reversible for body function.As what below summarized, the object of the invention is, based on deferential obturation, provide apparatus, the system and method for the male contraceptive of safety and comfort more.

Summary of the invention

In general, the present invention relates to a kind of male contraceptive apparatus, for obtaining the provisional sterile of boar individuality.Described apparatus comprises implantable restraint device, and described restraint device is suitable for the downstream area constraint deferent duct at ampulla within the controlled phase, and thus, described equipment can stop sperm to arrive urethra.Described apparatus further comprises control appliance, for controlling the operation of restraint device.Restraint device can comprise compressing equipment and stimulation apparatus hydraulic pressure or machinery, for retrain deferent duct independently or in any mode of combining temporarily.

Deferentially constrain in this and mean, the block system in this chamber makes, by from outside to deferential operation, stop sperm to arrive urethra.Term " deferent duct " can comprise a deferent duct or two deferent duct.When explain deferential controlled constraint according to the present invention, also use other terms, for example " chamber " or " tissue part " or " organ ", but these terms should be considered as synonym.Term " ampulla " represents deferential increase, and deferent duct converges with seminal vesicle near this.

Term " ampulla downstream " represents ampulla position (in the direction of urethra and seminal vesicle) below.Therefore, " ampulla upstream " represents the position (in the direction towards testis) before the ampulla on deferent duct.Restraint device is suitable for, at this specific region constraint deferent duct, preferably meaning that it is configured to receive in this region of health.

By realizing the downstream restrain deferent duct at ampulla, apparatus of the present invention allows reliable temporary sterilization by the sperm in shielding ampulla, and apparatus can be brought into play its contraceptive effect immediately thus.For example, even if the main uses of apparatus is that (during sexual life) stops sperm to be carried by starting restraint device within the controlled interim phase, some embodiment of the present invention also allows to support to carry sperm through deferent duct, to help the impaired individuality of this induction system.Advantageously, admissible constraint of the present invention required very short period.Existing processing mode need to be closed 5 days (this is the life-span of sperm) nearly before guaranteeing safety, and deferent duct has impaired danger thus.In addition, due to long-term constraint, apparatus stops sperm to accumulate in deferent duct, and this may cause undesirable complication.

Restraint device is very meticulous, is adapted to the ad-hoc location of ampulla.Space is limited, and the requirement that allows to be placed on the region between prostate and ampulla of deferent duct is clear and definite.Because ampulla comprises Sperm storage chamber, thus constraint carried out at downstream area, to prevent that sperm from arriving any probability of urethra during sexual intercourse.In appropriate, be also suitable for realizing that near seminal vesicle exit passageway is retrained according to restraint device of the present invention.To this exit passageway time, constraint should be considered as one of obtainable effect of the present invention.

According to one embodiment of present invention, restraint device comprises compressing equipment, and described compressing equipment is used at least a portion of the deferential tissue wall of oppressing ampulla downstream, to stop flowing in deferent duct.For this reason, described apparatus comprises scalable restraint device, also comprises operating equipment, described operating equipment for mechanically or hydraulic way operate described scalable restraint device, to change the constraint to deferential wall portion.Operating equipment is preferably with non-magnetic and/or non-manual mode operational constraints equipment.Preferably, operating equipment comprises electric operating equipment, for example motor or servosystem.Term " servosystem " means that this system comprises a kind of mechanism, and described mechanism is the brute force acting on another moving meter with short stroke by the weak power transmission acting on the moving meter with long stroke.Can select situation according to one, restraint device comprises compressing equipment, described compressing equipment comprises at least two long intermediate plate elements, on the flow direction of described intermediate plate element in deferent duct, on the not homonymy of this organ, extend along this organ, and operating equipment operates described intermediate plate element to clamp the wall portion between intermediate plate element, thereby oppress described wall portion.Operating equipment can selectively comprise hydraulic means and reverse servo, and described hydraulic means is for regulating restraint device with hydraulic way, and described reverse servo is operatively connected with described hydraulic means.It is the mechanism that acts on the weak power on another moving meter with long stroke that term " reverse servo " can be understood as the brute force transmission acting on the moving meter with short stroke.Preferably, reverse servo comprises at least two implantable containers that comprise hydraulic fluid, and preferably, the first container be can subcutaneous implantation adjusting container.Reverse servo further comprises the second implantable servo container, and described the second implantable servo container is preferably connected with described adjusting fluid container.In one embodiment, the second servo container is directly controlled the expansion/contraction of compressing equipment.In another embodiment, servo container is controlled the expansion/contraction of compressing equipment indirectly, wherein reverse servo further comprises the 3rd container, described the 3rd container is suitable for implanting abdominal part or retroperitoneum or pelvis area, and be operatively connected with the second servo container, for the hydraulic fluid of mobile described the 3rd container, thereby to compressing operate.Aptly, the 3rd container has the volume larger than the first container.The 3rd container can be connected with compressing equipment fluid, and servo container can be with mechanical connection control the 3rd container.

Selectively, restraint device comprises not inflatable mechanical pressure equipment, and operating equipment comprises hydraulic means, and described hydraulic means regulates mechanical pressure equipment with hydraulic way.

According to another embodiment of the present invention, restraint device comprises stimulation apparatus, for stimulate the wall portion of deferential tissue wall in the region in ampulla downstream, so that described wall portion shrinks, thereby affect mobile in deferent duct.Described in control appliance control, stimulation apparatus to be to stimulate described wall portion, and control appliance preferably can operate from patient body, to control implantable energy source, thereby discharges the energy relevant with stimulation.Stimulation apparatus is suitable for stimulating the zones of different of wall portion, and control appliance control stimulation apparatus is intermittent and stimulate individually these regions of wall portion.For the intermittent and independent stimulation of the zones of different of organ wall portion, allow, in the operating process that is organized in apparatus of the present invention of wall portion, to keep the blood circulation of normal.The multiple choices that realize constraint by stimulation and useful member are below described.

Be embodiments of the invention equally, restraint device comprises compressing and stimulation apparatus as above mechanically as above or hydraulic way operation.Control appliance is suitable for controlling compressing equipment and stimulation apparatus, to combine constraint deferent duct.

The present invention has also embodied the method that stimulates ampulla, comprises and uses the described apparatus with stimulation apparatus, at ampulla downstream restrain deferent duct.Obtain thus the adverse current of ampulla is stimulated.

The present invention further comprises system, is included in previously described any apparatus.In a preferred embodiment, this system comprises the switch at least one implantable patient body, controls described apparatus for manual and non-intervention.In another preferred embodiment, system comprises wireless remote control, controls described apparatus for non-intervention.In a preferred embodiment, system comprises the Hydraulically Operated Equipment for operating apparatus.In another embodiment, system comprises motor or the pump for operating apparatus.Other members of system are described in further detail in detailed description of the invention.

stimulate

When exciting nerve or when muscular tissue, correctly not carrying out if stimulated, make described tissue have the danger that damage occurs or worsen in time.Apparatus of the present invention is intended to reduce even eliminate this danger.Thus, according to the present invention, control appliance control stimulation apparatus is the zones of different of stimulatory organs's wall portion intermittently, thereby at different time points, at least two regions is stimulated, and stimulates and moves on to another region from a region in time.In addition, control appliance control stimulation apparatus, thus the current region not stimulated in zones of different is before stimulation apparatus stimulates this region again, recovers if having time the blood circulation of normal.In addition, control appliance control stimulation apparatus is in the each region of internal stimulus in period in succession, wherein each period enough short, to keep blood circulation satisfied in this region before finishing in this period.This has provided following advantage, and apparatus of the present invention can carry out continued stimulus to realize required mobile control to the wall portion of organ, and keeps in time in essence organ physiological property originally, does not damage the danger of organ.

In addition, change physically as described above the stimulation sites to organ, can on organ, produce the stimulation mode of promising change, to obtain required mobile control.

Control appliance can be controlled stimulation apparatus once stimulates one or more regions of wall portion, for example, by stimulating in turn zones of different.In addition,, preferably according to predetermined stimulation mode, control appliance can be controlled stimulation apparatus will be to the stimulation that circulates of these regions along wall portion.In order to obtain the required feedback of described tissue in histio-irritative process, control appliance can be controlled stimulation apparatus and preferably change the stimulus intensity to wall portion in the mode of circulation.

In a preferred embodiment of the invention, control appliance control stimulation apparatus by preferably form pulse train pulse interval stimulate territory, wainscot wall area.At least first area in territory, wainscot wall area and second area can stimulate with the first pulse train and the second pulse train respectively, and described the first and second pulse trains are relative to each other moved in time.For example, first area can stimulate with described the first pulse train, and second area does not stimulate with described the second pulse train, and vice versa.Selectively, the first and second pulse trains can relative to each other move, thereby described the first and second pulse trains overlap each other at least in part.

Pulse train can be constructed in a lot of different modes.Thus, control appliance can be controlled the idle period between umber of pulse and/or the pulse train of the repetition rate of the pulse of length, the pulse train of the width of each pulse of dutycycle that stimulation apparatus changes the individual pulse of amplitude, each pulse train of the pulse of pulse train, pulse train, each pulse train, the repetition rate of pulse train, each pulse train.Can use some heteroid pulse trains, to obtain required effect.

At control appliance control stimulation apparatus to change the idle period between the pulse train corresponding region of wall portion (stimulate), can be controlled as continuing long enough the each idle period between pulse train, when not stimulated in the phase at one's leisure in region below, recover the blood circulation of this region normal.

electricity irritation

According to a preferred embodiment of the invention, stimulation apparatus is powered stimulation equipment, and described powered stimulation equipment preferably carries out electricity irritation by electric pulse to the wall portion of patient body organ-tissue.This embodiment is particularly suitable for being applied in the situation that wall portion comprises the meat fiber that electricity irritation is fed back.In this embodiment, when Dang Bibu is in the oppression state, control appliance control stimulation apparatus passes through the preferably electric pulse stimulation wall portion of electrical pulse sequence form, to cause the contraction of wall portion.Certainly, the structure of electrical pulse sequence can be similar to above-mentioned pulse train, and control appliance can control stimulation apparatus, and the zones of different of the wall to organ is carried out electricity irritation in the same manner as described above.

Electrical stimulation apparatus comprises at least one aptly, and preferably multiple electric devices (for example electrode), for being combined with wall portion and with electric pulse, wall portion being stimulated.Optionally, electric device can relative to each other be placed with the orientation of fixing.Control appliance control electrical stimulation apparatus encourages one or one group of electric device at every turn.Preferably, control appliance control control electrical stimulation apparatus encourages each element in a looping fashion by electric pulse.Optionally, control appliance can be controlled stimulation apparatus electric device is encouraged, and makes sequentially an electric device to be encouraged at every turn, or encourages multiple simultaneously or organize electric device more.In addition can sequentially encourage many groups electric device randomly or according to predetermined way.

Electric device can form the electric device of any pattern.Preferably, electric device forms the electric device of pattern extending, and wherein electric device can be used on the wall of patient's organ, makes to extend the electric device of pattern along the wall longitudinal extension of organ, and the corresponding region of element adjacent wall portion.The electric device that extends pattern can comprise along a line or the multirow electric device of the wall longitudinal extension of organ.Every row electric device can form straight, spiral or tortuous electric device path, or the path of any pattern.Control appliance can be controlled stimulation apparatus along extending the electric device of pattern, in the direction contrary or identical with flow direction in patient's chamber, electric device is encouraged in succession.

Optionally, control appliance can be controlled stimulation apparatus, electric device is encouraged in succession towards the two ends of the electric device that extends pattern from the position that is substantially positioned at compressing Bi Bu center.In the case of the chamber of organ keeps closing relatively for a long time, control appliance can be controlled stimulation apparatus electric device is encouraged, make the electric device being energized form the electric device being energized of the pattern of two train waves, it advances towards the two ends of the electric device of Elongation Mode on two relative directions from compressing Bi Bu center simultaneously.Such ripple of the electric device being energized can repeat again and again, and can not damage organ, can any direction in the chamber of organ yet on mobile fluid or gas.

Control appliance is controlled aptly stimulation apparatus electric device is encouraged, and makes the current electric device being energized form at least one group of adjacent electric device being energized.According to the first selection, the element in the group of the electric device being energized forms a paths of the electric device being energized.The path of the electric device being energized can be extended around patient's organ at least in part.In the second selection, the element in the group of the electric device being energized can form two paths of the electric device being energized, and in the common side of patient's organ, extends, preferably basic transverse to the flow direction in patient's chamber.In the 3rd selects, the element in the group of the electric device being energized can form two above paths of the electric device being energized, and on the not homonymy of patient's organ, extends, preferably basic transverse to the flow direction in patient's chamber.

According to a preferred embodiment of the invention, electric device forms multicomponent part, and wherein these groups form a series of group, and the organ along patient on the flow direction in patient's chamber extends.Electric device in every group of electric device can forming element path, extend around patient's organ at least in part.In the first selection, extend on the not homonymy of patient's organ in two above paths that the electric device in every group of electric device can forming element, preferably basic transverse to the flow direction in patient's chamber.Control appliance can be controlled stimulation apparatus randomly or according to predetermined mode, the many groups electric device in a series of group be encouraged.Selectively, control appliance can be controlled stimulation apparatus, in the direction contrary or identical with flow direction in patient's chamber, or in two described directions from being substantially positioned at the center of wall portion of compressing, many groups electric device is encouraged in succession.For example, as mentioned above, the many groups of electric devices that are energized can form the electric device being energized of advancing wave pattern; Be that control appliance can be controlled stimulation apparatus many groups electric device is encouraged, make the electric device being energized form the electric device being energized of the pattern of two train waves, it advances towards the two ends of the electric device that extends pattern on two rightabouts from compressing Bi Bu center simultaneously.

Can be provided for the structure that electric device is held with the orientation of fixing.Although this structure can be separated with compressing equipment, but preferably, this structure assembly is in compressing equipment, and this is practical design and contributes to implant compressing equipment and stimulation apparatus.Form the electric device that extends pattern at electric device, this structure can be used on patient's organ, the electric device that makes to extend pattern extends along organ in the direction identical with flow direction in patient's chamber, and the corresponding region of the wall portion of element adjacent organs.

thermostimulation

In another embodiment of the present invention, stimulation apparatus carries out thermostimulation to the wall portion of organ.Thus, control appliance can control when stimulation apparatus is subject to oppressing in wall portion, wall portion is carried out cooling, to cause the compressing of wall portion.For example, compressing equipment can be oppressed wall portion at least to retrain flowing in chamber, and control appliance can be controlled stimulation apparatus, so that thereby the wall portion of compressing is carried out to cooling its contraction that makes, flowing in chamber at least further retrained, or further retrained but do not stop, or be prevented from.Selectively, when control appliance can be controlled stimulation apparatus and oppressed and shrink in wall portion to the heating of wall portion, to cause the expansion of wall portion.In the situation that wall portion comprises blood vessel, control appliance can be controlled the cooling blood vessel of stimulation apparatus so that it shrinks, or heating blood vessel is so that its expansion.In available part, thermostimulation can be implemented in any embodiment of the present invention, and thermostimulation can for example, in response to multiple sensors (damage, motion or pressure transducer) and controlled.

the compressing of sensor control and/or stimulation apparatus

As mentioned above, apparatus can comprise at least one implantable sensor, and wherein control appliance is in response to signal controlling compressing equipment and/or stimulation apparatus from sensor.Substantially, sensor directly or indirectly detects at least one physiological parameter of patient, or at least one functional parameter of apparatus, or at least one functional parameter of medical implant in patient body.

Can use a lot of dissimilar sensors to detect physiological parameter.For example, for example, for detection of the motion sensor of organ movement's (being natural shrinking, the contraction of stomach or intestinal), for detection of the pressure transducer of the pressure in organ, for detection of the damage sensor of organ damage, flow transducer for detection of the blood flow in the chamber of organ, spectrophotometric sensor, for detection of the pH value sensor of the Acidity of Aikalinity of fluid in the chamber of organ, for detection of the oxygen sensor of the oxygen content of fluid in the chamber of organ or for detection of the sensor of the distribution of stimuli on the organ being stimulated.Can use any sensor that can expect for detection of the useful physiological parameter of any other type.

The a lot of dissimilar sensor that detects the functional parameter of apparatus can also be used for controlling compressing equipment and/or stimulation apparatus.For example, for detection of the sensor of the electrical quantity of the implantation electric components of apparatus, or for detection of the sensor of the performance of the implantation motor of apparatus.

Sensor can comprise pressure transducer, detect as physiological parameter for the pressure in patient body, described pressure relates to the pressure in the chamber of patient's intracorporeal organ, wherein control appliance control compressing equipment and/or stimulation apparatus, to change the compressing to patient's wall portion in response to pressure transducer detects predetermined measured pressure value.

Can select pressure transducer, or be combined with pressure transducer, can setting position sensor, for patient is detected as physiological parameter with respect to the orientation of horizontal direction.Position sensor can be the form of the biocompatibility of displaying in United States Patent (USP) 4 942 668 and 5 900 909.For example, control appliance can be controlled compressing equipment and/or stimulation apparatus, to change the compressing to patient's wall portion in response to position sensor detects that patient has presented the direction of basic horizontal (being that patient lies down).

In available part, the sensor can be used in any embodiment of the present invention.

Control appliance can be controlled compressing equipment and/or stimulation apparatus, so that in response to time of one day and change the compressing of the wall portion to patient.For this reason, control appliance can comprise clockwork, for controlling compressing equipment and/or stimulation apparatus, to change the compressing to patient's wall portion, thereby in the different times of a day, increases or reduces the mobile impact in chamber.At sensor that above-mentioned any type is set for detecting physiology or functional parameter, if the parameter that sensor detects does not have precedence over clockwork, clockwork is used for controlling compressing equipment and/or stimulation apparatus, if or clockwork do not have precedence over sensor, sensor is used for controlling compressing equipment and/or stimulation apparatus.

Aptly, control appliance produces instruction, the information of for example acoustical signal or demonstration in response to the signal from sensor.

Control appliance can comprise implantable internal control unit, and described internal control cell response is directly controlled restraint device and/or stimulation apparatus in the signal from sensor.Control appliance may further include wireless remote controller, and described wireless remote controller is suitable for setting the control parameter of internal control unit from patient body, and without mechanically getting involved patient.Control parameter (can be set by wireless remote controller) at least one of them is physiology or functional parameter.Aptly, internal control unit comprises above-mentioned clockwork, and wherein wireless remote controller is also suitable for setting clockwork.

Selectively, control appliance can comprise the external control unit outside patient body, for signal controlling compressing equipment and/or stimulation apparatus in response to from sensor.

Brief description of the drawings

Now, by the example of indefiniteness and with reference to accompanying drawing, the present invention is described in further detail, wherein:

Figure 1A to 1F schematically shows the apparatus according to implant into body of the present invention.

Fig. 1 G shows the system that is used for the treatment of disease, and wherein this system comprises the apparatus in the patients with implantation body among Figure 1A to 1F arbitrarily.

Fig. 2-16 schematically show multiple embodiment of system, for encouraging the apparatus shown in Figure 1A-1F with wireless mode.

Figure 17 schematically arranges block diagram, for providing the energy of accurate amount with the apparatus shown in application drawing 2.

Figure 18 schematically shows the embodiment of system, the energy operating apparatus wherein fettering by wire.

Figure 19 is more detailed layout block diagram, for the transmitting of controlling wireless energy with the apparatus shown in application drawing 2.

Figure 20 is the circuit for arranging shown in Figure 19 according to possible embodiment.

Figure 21-27 show the multiple arrangement that the apparatus in patients with implantation body is carried out to hydraulic pressure or air-operated drive.

Detailed description of the invention

Figure 1A is the schematic diagram of the apparatus for male contraceptive shown in Figure 1B.The apparatus 100 of Figure 1B is illustrated in the constraint that ampulla of deferent duct 220A, 220B downstream carry out deferent duct 200A, 200B.Thus, described apparatus is operable as, and provisional prevention arrives urethra and in limited time sterile is provided.Apparatus 100 has restraint device 120 and control appliance 150, described restraint device 120 is suitable for mechanically or hydraulic way compressing deferent duct, and in the time that restraint device 120 operates by the operating equipment 170 schematically showing, described control appliance is for controlling the operation of restraint device.Control appliance 150 is positioned at subcutaneous, and comprises exterior section and interior section.Energy supply device unit (energy transmitter) 180 can be by the Power supply equipment of wireless transmit (being transmitted into energy conversion 151), energy conversion 151 is connected with energy source 152, for by the energy expenditure parts of Power supply apparatus.Outside RCU 190 can be communicated by letter with the control appliance of control appliance 150 internal control unit 153.The exterior section 150A of control appliance 150 comprises the function that peripheral operation is required, for example injection port and start/stop button, injection port is for hydraulic fluid (hydraulic fluid) is provided in the time oppressing with hydraulic way, and start/stop button is for operational constraints equipment.The interior section 150B of control appliance can comprise control and the required multiple functions of operational constraints equipment 120.In the restraint device 120 of hydraulic way operation, control appliance 150 can be included in the pump 154 that can turn round on the container (not shown) for hydraulic fluid, thus, conveying from the fluid of described container makes restraint device start to retrain deferent duct, and the conveying of returning to described container makes restraint device close down to unclamp deferent duct.Fig. 1 C shows the apparatus without any Figure 1B of control appliance.In restraint device 120 and Figure 1B is same type, but is suitable for retraining deferent duct and seminal vesicle passing away at this.Fig. 1 D shows the apparatus of Figure 1B or 1C, with the restraint device 120A of the transformation operating by the stimulation apparatus on the deferent duct of both sides.Described stimulation apparatus is represented by one group of electrode at this.Fig. 1 E shows the apparatus of Figure 1B or 1C, with the restraint device (by control appliance control) that comprises stimulation apparatus 120A and compressing equipment 120B, to retrain the deferent duct of both sides by the interlock of described stimulation apparatus and described compressing equipment.In one embodiment, compressing equipment 120B is by pump manual operation (described pump turns round in container), to carry out the compressing on deferent duct, and the stimulation apparatus being operated by control appliance stimulates deferent duct, the blocking effect of carrying to realize sperm.Fig. 1 F shows another variation of the apparatus of Figure 1B, and wherein, restraint device 120 comprises two compressing equipment, and each compressing equipment is suitable for oppressing deferent duct and seminal vesicle passing away, to hinder respectively flowing of sperm and seminal fluid.The function of control appliance and miscellaneous part of the present invention will below further explained to 27C in conjunction with Fig. 1 G.

Fig. 1 G shows the system that is used for the treatment of disease, comprises the apparatus of the present invention 1010 that is placed on patient's abdominal part.The energy conversion 302 of implanting is suitable for the energy expenditure parts supplying energy to apparatus via power line 303.For excite the external energy transmitter 304 of apparatus 10 by least one wireless energy signal emitted energy non-interventionly.The energy conversion 1002 of implanting is converted to energy the electric energy of supplying via power line 1003 from wireless energy signal.

Wireless energy signal can comprise ripple signal, and described ripple signal is selected from: acoustic signals, ultrasonic signal, electromagnetic wave signal, infrared signal, visible light signal, ultraviolet signal, laser signal, microwave signal, radio wave signal, x x radiation x signal and gamma radiation signal.Selectively, wireless energy signal can comprise electric field or magnetic field, or the Electric and magnetic fields of combination.

Wireless energy transmitter 1004 can be launched the carrier signal for carrying described wireless energy signal.Such carrier signal can comprise the signal of numeral, simulation or Digital and analog combination.In this case, wireless energy signal comprises analog or digital signal, or the signal of analog-and digital-combination.

Generally speaking, energy conversion 1002 is set to, and is converted to the energy of conventionally different from the energy of the first form the second forms for the wireless energy of the first form that energy transmitter 1004 is launched.The apparatus 10 of implanting can be in response to the energy operation of the second form.When the wireless energy of first form of energy transmitter 1004 being launched when energy conversion 1002 is converted to the energy of the second form, energy conversion 1002 can directly carry out energy supply with the energy of the second form to apparatus.System may further include implantable accumulator, and wherein the energy of the second form is at least in part for to described charge in batteries.

Selectively, in the time that wireless energy is just launched by energy transmitter 1004, the wireless energy that energy transmitter 1004 is launched can be directly used in apparatus is carried out to energy supply.As described below, comprise the operating equipment for operating described apparatus in system, the wireless energy that energy transmitter 1004 is launched can be directly used in described operating equipment is carried out to energy supply, to produce the kinetic energy for the operation of described apparatus.

The wireless energy of the first form can comprise sound wave, and energy conversion 1002 can comprise the piezoelectric element for sound wave being converted to electric energy.The electric energy form that the energy of the second form can comprise is: unidirectional current or Rectified alternating current, or the combination of unidirectional current and Rectified alternating current, or the combination of alternating current or unidirectional current and alternating current.Conventionally, apparatus comprises the electric components being encouraged by electric energy.Other implantable electric components of system can be at least one voltage level limiter or at least one the constant current limiters being connected with the electric components of apparatus.

Optionally, one of the energy of the first form and energy of the second form can comprise magnetic energy, kinetic energy, acoustic energy, chemical energy, radiant energy, electromagnetic energy, luminous energy, nuclear energy or heat energy.Preferably, one of the energy of the first form and energy of the second form are non-magnetic, non-power, non-chemically, non-sound wave, non-core or non-thermal.

Energy transmitter can be controlled from patient body, and to discharge electromagnetic wireless energy, and the electromagnetic wireless energy discharging is used for operating described apparatus.Selectively, energy transmitter is controlled from patient body, and to discharge the wireless energy of non-magnetic, and the wireless energy of the non-magnetic discharging is used for operating described apparatus.

External energy transmitter 1004 also comprises wireless remote controller, and described wireless remote controller has the external signal emitter for launching wireless control signal, to control described apparatus non-interventionly.The implanted signal receiver of control signal receives, and described signal receiver can combine with the energy conversion 1002 of implanting or be separated.

Wireless control signal can comprise frequency modulation, amplitude modulation or phase-modulated signal or their combination.Selectively, wireless control signal comprises analog or digital signal, or the combination of analog and digital signal.Selectively, wireless control signal comprises electric field or magnetic field, or the Electric and magnetic fields of combination.

Wireless remote controller can be launched the carrier signal for carrying wireless control signal.Such carrier signal can comprise the combination of numeral, analog or digital and analogue signal.The signal that comprises analog or digital signal or analog-and digital-combination in control signal, wireless remote controller is preferably launched the electromagnetic carrier wave signal for carrying numeral or analog control signal.

Fig. 2 shows the system in Fig. 1 G with the block diagram form of more summarizing, the energy conversion 1002 and the external energy transmitter 1004 that show apparatus 10, via power line 1003, apparatus 10 are carried out energy supply.Patient's skin 1005 (substantially being represented by vertical curve) separates the inside of the patient body on line right side and the outside in line left side.

Fig. 3 shows the embodiments of the invention identical with Fig. 2, and except the counter-directional device of electric switch 1006 forms in same patients with implantation body, for by reverse apparatus 10, described electric switch for example can operate by polarization energy.In the time that switch is operated by polarization energy, the wireless signal of the wireless remote controller transmitting carrying polarization energy of external energy transmitter 1004, and wireless polarization energy is converted to the current of polarization for operating electric switch 1006 by the energy conversion 1002 of implanting.In the time that the implanted energy conversion 1002 of the polarity of electric current changes, the function that electric switch 1006 is carried out apparatus 10 is reverse.

Fig. 4 shows the embodiments of the invention identical with Fig. 2, and except the operating equipment 1007 for apparatus 10 is operated in patients with implantation body, described operating equipment is arranged between the energy conversion 1002 and apparatus 10 of implantation.This operating equipment can be the form of motor 1007 (for example servomotor).When the remote control unit of external energy transmitter 1004 is during to the receptor wireless signal emission of the energy conversion 1002 of implanting, motor 1007 is by the energy energy supply of the energy conversion 1002 from implanting.

Fig. 5 shows the embodiments of the invention identical with Fig. 2, and just the embodiment of Fig. 5 also comprises the operating equipment of device 1008 forms, device 1008 motor/pump unit 1009 and the fluid containers 1010 that comprise in patients with implantation body.In this case, apparatus 10 operates with hydraulic way, be that hydraulic fluid is pumped into apparatus 10 from fluid container 1010 through conduit 1011 by motor/pump unit 1009, so that apparatus is operated, and hydraulic fluid is drawn back fluid container 1010 by motor/pump unit 1009 from apparatus 10, so that apparatus correcting action.Wireless energy is converted to electric current (for example current of polarization) by the energy conversion 1002 of implanting, for motor/pump unit 1009 being carried out to energy supply via power line 1012.

Be also contemplated that operating equipment comprises that pneumatic handling equipment substitutes the apparatus 10 with hydraulic way operation.In this case, hydraulic fluid can be the forced air for regulating, and fluid container is replaced by air chamber.

In all these embodiment, energy conversion 1002 can comprise rechargeable accumulator (for example battery or the capacitor being charged by wireless energy), and energy conversion any energy expenditure parts supplying energy that is system.

As selection, above-mentioned wireless remote controller can be replaced by the hand-control device of any implantation parts, is for example positioned at subcutaneous button with the hands contact (being likely mediate contact) by patient.

Fig. 6 shows embodiments of the invention, comprise with external energy transmitter 1004, the apparatus 10 (in this case with hydraulic way operation) of its wireless remote controller and the energy conversion 1002 of implanting, and further comprise hydraulic fluid container 1013, motor/pump unit 1009 and adopt the counter-directional device of hydraulic valve mobile device 1014 forms, in all these patients with implantation body.Certainly, hydraulic operation can easily be carried out by only changing pumping direction, and therefore can omit hydraulic valve.Remote control unit can separate with external energy transmitter, or is included in wherein.The motor of motor/pump unit 1009 is electro-motors.In response to the control signal of the wireless remote controller from external energy transmitter 1004, the energy conversion 1002 of implanting carries out energy supply to motor/pump unit 1009, institute's energizing quantity is from the energy of control signal carrying, thus, motor/pump unit 1009 is distributed in hydraulic fluid between hydraulic fluid container 1013 and apparatus 10.The remote control unit control hydraulic valve mobile device 1014 of external energy transmitter 1004, so that the flow direction of hydraulic fluid is changed between following both direction, in one direction, fluid is pumped into apparatus 10 by motor/pump unit 1009 from hydraulic fluid container 313, to operate described apparatus, and on another rightabout, fluid is drawn back hydraulic fluid container 1013 by motor/pump unit 1009 from apparatus 10, make described apparatus correcting action.

Fig. 7 shows embodiments of the invention, comprises with external energy transmitter 1004, apparatus 10, the energy conversion 1002 of implanting, the internal control unit 1015 (wireless remote controller by external energy transmitter 1004 is controlled) of implanting, the accumulator 1016 of implanting of its wireless remote controller and the capacitor 1017 of implanting.Internal control unit 1015 arranges the storage in accumulator 1016 of electric energy that the energy conversion 1002 from implanting receives, and described accumulator is to apparatus 10 supplying energies.In response to the control signal of the wireless remote controller from external energy transmitter 1004, internal control unit 1015 discharges the energy discharging from the electric energy of accumulator 1016 and via power line 1018 and 1019 conversions, or via power line 1020, the capacitor 1017 that makes current stabilization, power line 1021 and power line 1019, directly conversion is from the electric energy of the energy conversion device 1002 of implanting, for the operation of apparatus 10.

Internal control unit is preferably programmable outside patient body.In a preferred embodiment, internal control unit is programmed to, according to the timetable of layout in advance or according to the input from any sensor (detecting patient's any possible physiological parameter or any functional parameter of system), apparatus 10 is regulated.

According to selection situation, can omit the capacitor 1017 in the embodiment of Fig. 7.According to another selection situation, can omit the accumulator 1016 in this embodiment.

Fig. 8 shows and embodiments of the invention identical in Fig. 2, and except going back battery 1022 and the electric switch 1023 in patients with implantation body, described battery is used for supplying energy to apparatus 10 is operated, and described electric switch is for switching the operation of apparatus 10.Electric switch 1023 can be by remote control unit control, and the energy that can supply by the energy conversion 1002 of implanting operates, to be switched to conduction mode from cut-off mode, in cut-off mode, battery 1022 is not in using state, battery 1022 supplying energies in conduction mode, for the operation of apparatus 10.

Fig. 9 shows and embodiments of the invention identical in Fig. 8, except going back the internal control unit 1015 in patients with implantation body, can control described internal control unit by the wireless remote controller of external energy transmitter 1004.In this case, the energy operation that electric switch 1023 is supplied by the energy conversion 1002 of implanting, to be switched to standby from cut-off mode, in cut-off mode, stop wireless remote controller control internal control unit 1015 and battery not in using state, in standby, allow remote control unit control internal control unit 1015 to discharge the electric energy from battery 1022, for the operation of apparatus 10.

Figure 10 shows and embodiments of the invention identical in Fig. 9, and the member that is substituted and implant by accumulator 1016 except battery 1022 interconnects by different way.In this case, accumulator 1016 is stored the energy from the energy conversion 1002 of implanting.In response to the control signal of the wireless remote controller from external energy transmitter 1004, internal control unit 1015 is controlled electric switch 1023 and is switched to conduction mode from cut-off mode, in cut-off mode, accumulator 1016 is not in using state, in conduction mode, accumulator 1016 supplies the energy of the operation that is applied to apparatus 10.Accumulator can be combined with capacitor or be substituted by capacitor.

Figure 11 shows and embodiments of the invention identical in Figure 10, except in battery 1022 also implanted patient body and implant member interconnect by different way.In response to the control signal of the wireless remote controller from external energy transmitter 1004, internal control unit 1015 is controlled accumulator 1016 and is transmitted energy, be used for operating electric switch 1023 and be switched to conduction mode from cut-off mode, in cut-off mode, battery 1022 is not in using state, in conduction mode, battery 1022 supplies the electric energy of the operation that is applied to apparatus 10.

Selectively, the energy that can supply by accumulator 1016 operates electric switch 1023, to be switched to standby from cut-off mode, in cut-off mode, stop wireless remote controller control battery 1022 to supply electric energy and wireless remote controller not in using state, in standby, allow wireless remote controller control battery 1022 to supply electric energy, for the operation of apparatus 10.

Should be understood that, switch every other in switch 1023 and this application should make an explanation in its most wide in range embodiment.This refers to can the conducting of Switching power and the transistor of cut-off, MCU, MCPU, ASIC, FPGA or DA transducer or any other electronic devices and components or circuit.Preferably, from health external control switch, or selectively, by the internal control unit controls switch of implanting.

Figure 12 shows and embodiments of the invention identical in Fig. 8, except going back the mechanical counter-directional device of motor 1007 in patients with implantation body, change speed gear box 1024 forms and for controlling the internal control unit 1015 of change speed gear box 1024.Oppositely (the mechanically operation) of function that change speed gear box 1024 is carried out apparatus 10 controlled in internal control unit 1015.Even more simply, change the direction of motor in electronic mode.The change speed gear box of explaining in its most wide in range embodiment can represent labour-saving servomechanism installation, plays a role for the operating equipment of supporting longer stroke.

Figure 13 shows and embodiments of the invention identical in Figure 19, except the member of implanting interconnects by different way.Thus, in this case, when accumulator 1016 (being capacitor aptly) starts electric switch 1023 when being switched to conduction mode, internal control unit 1015 is powered by battery 1022.When electric switch 1023 is during in its conduction mode, allow internal control unit 1015 to control battery 1022 and provide or do not provide energy for the operation of apparatus 10.

Figure 14 schematically shows the combination that can expect of the implantation member of apparatus, selects for reaching multiple communication.Mainly contain apparatus 10, internal control unit 1015, motor or pump unit 1009 and comprise the external energy transmitter 1004 of external wireless remote control unit.As mentioned above, wireless remote controller is launched the control signal being received by internal control unit 1015, the member of multiple implantation of internal control unit and then control device.

Preferably include the feedback device of sensor or measurement device 1025 can patients with implantation body in, for detection of patient's physiological parameter.Physiological parameter can be at least one that select the group from being made up of following parameters: pressure, volume, diameter, broadening, amount of elongation, elongation, motion, bending, elasticity, muscle contraction, neural impulse, body temperature, blood pressure, blood flow, heart beating and breathing.Sensor can detect above-mentioned physiological parameter arbitrarily.For example, sensor can be pressure or motion (motility movement) sensor.Selectively, can arrange sensor 1025 measuring ability parameters.Functional parameter can be relevant to the power transfer of the energy source charging for to implanting, and functional parameter may further include at least one that select the group from being made up of following parameters: electric power, any electrical quantity, pressure, volume, diameter, broadening, amount of elongation, elongation, motion, bending, elasticity, temperature and flow.

Feedback can send to internal control unit, or (preferably via internal control unit) outwards sends to external control unit.Feedback can or send to external with the independently communication system of receptor and emitter via energy transmission system.

Internal control unit 1015, or selectively, the external wireless remote control unit of external energy transmitter 1004, can be in response to the signal from sensor 1025 control device 10.Transceiver can with sensor 1025 combinations, for the information of the physiological parameter that relates to detection is sent to external wireless remote control unit.Wireless remote controller can comprise signal projector or transceiver, and internal control unit 1015 can comprise signal receiver or transceiver.Selectively, wireless remote controller can comprise signal receiver or transceiver, and internal control unit 1015 can comprise signal projector or transceiver.Above-mentioned transceiver, emitter and receptor can in patient body to the external transmission information relevant to apparatus 10 or data.

In the case of motor/pump unit 1009 and for encourage the battery 1022 of motor/pump unit 1009 implanted, the information relevant to the charging of battery 1022 can be fed.For more accurate, when, sending the energy back information relevant to described charging process, and change thus energy supply during to battery or charge in batteries with energy.

Figure 15 shows selectable embodiment, and wherein apparatus 10 regulates from patient body.System 1000 comprises the battery 1022 that is connected to apparatus 10 via subcutaneous electric switch 1026.Thus, the adjusting of apparatus 10 is carried out by the subcutaneous switch of Manual press non-interventionly, and operating between conducting and cut-off of apparatus 10 switched thus.Will be understood that the embodiment illustrating simplifies, and additional assembly, disclosed any other the parts of for example internal control unit or the application can add system.Can also use two subcutaneous switches.In a preferred embodiment, the switch of an implantation sends information to inner control unit, and to realize certain predetermined implementation status, and in the time that patient presses switch again, implementation status is reverse.

Figure 16 shows selectable embodiment, and wherein system 1000 comprises the hydraulic fluid storage capsule 1013 being connected with apparatus with hydraulic way.The hydraulic container that non-intervention adjusting is connected with apparatus by Manual press is realized.

System can comprise external data communication device and the implantable internal data communicator of communicating by letter with external data communication device.Inside plant is fed to the data relevant to apparatus or patient to outside data communication equipment, and/or external data communication device is to inner data communication equipment data feed.

Figure 17 has schematically described the layout of system, this layout can from patient body to external transmission information, relevant at least one functional parameter of apparatus or system to provide, or the feedback information relevant to patient's physiological parameter, thereby the energy that accurate amount is provided to the internal energy receptor 1002 of implanting, described internal energy receptor is connected with the energy expenditure member of the implantation of apparatus 10.Such energy receiver 1002 can comprise energy source and/or energy conversion.In brief, wireless energy is launched from the exterior source of energy 1004a that is positioned at patient outside, and is received by the internal energy receptor 1002 that is positioned at patient body.Internal energy receptor is suitable for the energy receiving to the energy expenditure member supply of apparatus 10 via switch 1026 directly or indirectly.Between the energy that the energy receiving at internal energy receptor 1002 and apparatus 10 use, determine the energy balance, and the then energy balance based on definite and control the transmitting of wireless energy.The energy balance provides the accurate instruction for required appropriate energy thus, and required appropriate energy is enough for proper operation apparatus 10, and does not cause undue temperature rise.

In Figure 17, patient's skin is represented by vertical curve 1005.At this, energy receiver comprises the energy conversion 1002 that is positioned at patient body, is preferably just positioned under patient skin 1005.Generally speaking, the energy conversion 1002 of implantation can be placed on abdominal part, chest, muscular fascia (for example, in abdominal wall), subcutaneous or other suitable positions arbitrarily.The energy conversion 1002 of implanting is suitable for receiving the wireless energy E from exterior source of energy 1004a (being arranged on external energy transmitter 1004) transmitting, external energy transmitter 1004 is positioned at outside patient skin 1005, the contiguous energy conversion 1002 of implanting.

Just as is known in the art, wireless energy E conventionally can be by the power transfer of suitable percutaneous (TET) device transmission, for example, comprise the equipment of the secondary coil (being arranged in the energy conversion 1002 of implantation) of primary coil (being arranged in exterior source of energy 1004a) and vicinity.In the time being fed to electric current through primary coil, the energy of voltage form is responded in secondary coil, this energy can be for the energy expenditure member energy supply of the implantation to apparatus, for example, for example, in the energy source (rechargeable battery or capacitor) that the stored energy arriving is being implanted after.But the present invention is not limited to any specific energy transmission technology conventionally, TET equipment or energy source, and can use the wireless energy of any kind.

The energy comparison that the amount of the energy that the energy receiver of implanting receives can be used with the implantation member of apparatus.Term " energy of use " is interpreted as thus and also comprises the energy of being stored by the implantation member of apparatus.Control appliance comprises external control unit 1004b, and the energy balance of described external control unit based on definite controlled exterior source of energy 1004a, with the transmission quantity of adjusting energy.In order to transmit appropriate energy, the internal control unit 1015 of the demand of the energy balance and energy by comprising implantation really locking equipment determine, this determines that equipment comprises the internal control unit 1015 being connected between switch 1026 and apparatus 10.Thus, internal control unit 1015 can be arranged to, reception is by the suitable sensor of certain specific character of measuring apparatus 10 or multiple measurement results that similar device (not shown) obtains, and this characteristic has reflected the energy requirement amount of proper operation apparatus 10 in some way.In addition, the current situation of patient also can detect by suitable measurement device or sensor, to the parameter of reaction status of patient is provided.Thus, such characteristic and/or parameter can be for example, to the current state of apparatus 10 (power consumption, operator scheme and temperature) relevant, also relevant to the situation of for example, patient by parameter (body temperature, blood pressure, heart beating and breathing) reflection.The physiological parameter of other kinds and functions of the equipments parameter are described elsewhere.

In addition, the energy source of accumulator 1016 forms can optionally be connected to the energy conversion 1002 of implantation via control unit 1015, for accumulating the energy of reception to use after apparatus 10.Selectively or additionally, can also measure the characteristic of such accumulator, this characteristic has also reflected energy requirement amount.Accumulator can be substituted by rechargeable battery, and the characteristic of measuring can be to the current state of battery, electrical quantity (such as energy expenditure voltage, temperature etc.) is relevant arbitrarily.In order to provide enough voltage and currents to apparatus 10, and also for fear of overheated, can know understanding, battery should be by receiving appropriate energy from the energy conversion 1002 of implanting and optimally charging, can be not very few can be not too much yet.Accumulator can also be the capacitor with individual features.

For example, can periodic measurement battery behavior, to determine the current state of battery, the current state of battery then can be used as in the suitable storage device that status information is stored in internal control unit 1015.Thus, no matter when carry out new measurement, the battery status information of storage can correspondingly upgrade.Like this, the state of battery can be by the appropriate energy of transmission by " calibration ", to battery is remained on to optimum condition.

Thus, the measurement result that measurement device based on the sensor or apparatus 10 obtains, or patient, or the energy source of implanting (if use), or their combination, determines that the internal control unit 1015 of equipment is suitable for determining the energy balance and/or current energy requirement amount (energy of unit interval or the energy of accumulation).Internal control unit 1015 is further connected with internal signal emitter 1027, and described internal signal emitter is arranged to, to the control signal of the definite energy requirement amount of the external signal receptor 1004c transmitting reflection being connected with external control unit 1004b.In response to the control signal receiving, can then regulate from the amount of the energy of exterior source of energy 1004a transmitting.

Selectively, determine that equipment can comprise external control unit 1004b.In this possibility, sensor measurement can be directly to outside control unit 1004b transmitting, wherein the energy balance and/or current energy requirement amount can be determined by external control unit 1004b, thus the integrated above-mentioned functions of internal control unit 1015 in outside control unit 1004b.In this case, can omit internal control unit 1015, and sensor measurement is directly supplied with to internal signal emitter 1027, described internal signal emitter sends measurement result to outside signal receiver 1004c and external control unit 1004b.Based on those sensor measurements, the energy balance and current energy requirement amount can be determined by external control unit 1004b.

Thus, use the information feedback of instruction institute energy requirement according to the current solution of Figure 17 configuration, this is more more effective than solution before, because it is the actual use of energy based on compared with the energy receiving, for example, for the energy acceptance rate compared with the energy utilization rate of amount, the energy difference of energy or the energy expenditure member implanted with apparatus.Apparatus can use the energy of reception, for consuming or for storing the energy in energy source or the similar device of implantation.If suitable and needs, will use above-mentioned different parameter, and set it as the instrument of determining the real energy balance.But such parameter itself can also be used for any action that take inside, so that apparatus is carried out to concrete operations.

Use suitable signal (for example radio, IR (infrared) or ultrasonic signal) transmitting device, internal signal emitter 1027 and external signal receptor 1004c can be implemented as independently unit.Selectively, internal signal emitter 1027 and external signal receptor 1004c can be integrated into respectively in the energy conversion 1002 and exterior source of energy 1004a of implantation, to mainly use identical lift-off technology, in the direction contrary with power transfer, transmit control signal.Control signal can be modulated for frequency, phase place or amplitude.

Thus, feedback information can transmit by the independently communication system that contains receptor and emitter, or is integrated in energy system.According to the present invention, integrated information feedback like this and energy system comprise implantable internal energy receptor for receiving wireless energy and for launching the external energy emitter of wireless energy, described energy receiver has inner the first coil and the first electronic circuit being connected with described the first coil, and described energy emitter has outside the second coil and the second electronic circuit being connected with described the second coil.The outside second coil transmitting wireless energy of energy emitter, wireless energy is received by the first coil of energy receiver.This system further comprises for switching inner the first coil and the conducting being connected of the first electronic circuit and the on and off switch of cut-off, make in the time that on and off switch switches the conducting being connected of inner the first coil and the first electronic circuit and cut-off, the feedback information relevant to the charging of the first coil is by external energy transmitter receipt, and reception form is that the load impedance of outside the second coil changes.In the time implementing the configuration of this system in Figure 17, switch 1026 is independently and by internal control unit 1015 to control, or switch 1026 is integrated in internal control unit 1015.Should be understood that, switch 1026 should make an explanation in its most wide in range embodiment.This refers to the transistor of opening and closing, MCU, MCPU, ASIC FPGA or DA transducer or any other electronic devices and components or circuit that can Switching power.

In a word, the configuration of the energy supply shown in Figure 17 can mainly operate in the following manner.First the energy balance is determined by the internal control unit 1015 of determining equipment.The control signal of reflection energy requirement amount is also produced by internal control unit 1015, and control signal is launched to outside signal receiver 1004c from internal signal emitter 1027.Selectively, the energy balance can be determined by external control unit 1004b, instead of depend on realization as above.In this case, control signal can be carried the measurement result from multiple sensors.The energy balance (for example, in response to the control signal receiving) based on definite, the amount of the energy of exterior source of energy 1004a transmitting can then be regulated by external energy control unit 1004b.This process can, during lasting power transfer, be carried out intermittence with specific interval and repeat, or can during power transfer, carry out basic continous.

The transmission quantity of energy can for example, regulate by multiple emission parameters (voltage, electric current, amplitude, ripple frequency and pulse characteristic) of adjusting in exterior source of energy 1004a conventionally.

This system can also be used for obtaining the information about the degree of coupling between TET system coil, even can be for calibration system, to find external coil with respect to the optimal location of Inside coil and power transfer is optimized.Compare simply in this case transmission quantity and the quantities received of energy.For example, if external coil moves, the degree of coupling may change, and the correct movement showing can make external coil find the optimal location for power transfer.Preferably, external coil is suitable for calibrating the transmission quantity of energy, to obtained the feedback information of determining in equipment before the degree of coupling is maximized.

This degree of coupling information can also be as feedback during power transfer.Under these circumstances, energy system of the present invention comprises implantable internal energy receptor for receiving wireless energy and for launching the external energy emitter of wireless energy, described energy receiver has inner the first coil and the first electronic circuit being connected with described the first coil, and described energy emitter has outside the second coil and the second electronic circuit being connected with described the second coil.The outside second coil transmitting wireless energy of energy emitter, wireless energy is received by the first coil of energy receiver.This system further comprises the feedback device for outwards transmitting the energy quantities received of the first coil as feedback information, and wherein the second electronic circuit comprises definite equipment, for receiving feedback information, and for the power transfer amount of the second coil is compared with feedback information (relevant to the energy quantities received of the first coil), to obtain the degree of coupling between the first and second coils.In response to the degree of coupling obtaining, energy emitter can regulate the energy of transmitting.

With reference to Figure 18, although be described as above carrying out non-intervention operation for the wireless transmission of energy that apparatus is operated, will be understood that the energy operation that described apparatus can also fetter by wire.Figure 18 shows such example, and wherein external switch 1026 is for example connected to, between exterior source of energy 1004a and operating equipment (electro-motor 1007 apparatus 10 being operated).External control unit 1004b controls the operation of external switch 1026, to realize the proper operation of apparatus 10.

Figure 19 shows different embodiment, and how the energy receiving can supply with apparatus 10 and by its use.Similar to the example in Figure 17, internal energy receptor 1002 receives the wireless energy E from exterior source of energy 1004a, and energy source 1004a is controlled by emission controlling unit 1004b.Internal energy receptor 1002 can comprise constant-voltage circuit, by the dotted line frame in figure " constant V " represent, for constant voltage to apparatus 10 supplying energies.Internal energy receptor 1002 may further include constant current circuit, by the dotted line frame in figure " constant C " represent, for constant current to apparatus 10 supplying energies.

Apparatus 10 comprises energy expenditure parts 10a, and energy expenditure parts 10a can be motor, pump, restraint device or need energy for its electrically operated any other armarium.Apparatus 10 may further include energy storage device 10b, the energy of supplying for storing internal energy receptor 1002.Thus, the energy of supply can directly be consumed by energy expenditure parts 10a, or is stored by energy storage device 10b, or the energy providing can partly be consumed part be stored.Apparatus 10 may further include energy stabilization unit 10c, for the energy stabilization that internal energy receptor 1002 is supplied.Thus, energy can be with mode of oscillation supply, thus consume or storage before, be necessary to make energy stabilization.

Before being consumed and/or stored by apparatus 10, the energy that internal energy receptor 1002 is supplied can be by the further accumulation and/or stable of independently energy stabilization unit 1028 that is positioned at apparatus 10 outsides.Selectively, energy stabilization unit 1028 can be integrated in internal energy receptor 1002.No matter which kind of situation, energy stabilization unit 1028 all can comprise constant-voltage circuit and/or constant current circuit.

It should be noted that about the several functions member illustrating and element and how to arrange and to be connected to each other, Figure 17 and Figure 19 show that some are possible and infinite realization is selected.But technical staff is readily appreciated that, within the scope of the present invention, can much changes and revise.

Figure 20 schematically shows the energy balance measuring circuit of one of recommendation design of system, for controlling the transmitting of wireless energy, or shows energy balance control system.Circuit has the output signal that is centered close to 2.5V, and unbalance relevant pro rata to energy.The derivative of this signal represents whether signal value rises and the speed of decline and this change generation.If the energy that the quantities received of energy uses lower than the implantation member of apparatus, more energy is transmitted and is filled with energy source.Conventionally be fed to A/D converter and be converted to number format from the output signal of circuit.Digital information can then send to external energy transmitter, allows it to regulate the level of the energy of transmitting.Another probability is to have analog systems thoroughly, and its use comparator compared with specific minimum and maximum threshold value, if balance deviation goes out maximum/minimum window, sends information to external energy transmitter by energy balance level.

Signal Figure 20 shows for the circuit of system and realizes, and system use vicarious power transfer is given power transfer the energy member of the apparatus of the present invention of implanting from patient body.Vicarious energy transmission system uses external emission coil and inner receiving coil conventionally.Schematic diagram 3 comprises receiving coil L1, does not comprise the radiating portion of system.

Certainly the realization of the general concept of the energy balance and information transmitting can be implemented with multitude of different ways certainly to the method for external energy emitter.The method of signal Figure 20 and above-mentioned estimation and transmitting information, should only be regarded as how implementing the example of control system.

Circuit details

In Figure 20, the test point in the indication circuits such as symbol Y1, Y2, Y3.Components and parts in figure and their values are separately work values in this particular example, and this embodiment is one of limited possible design certainly.

The energy of circuit energy supply is received by energy receiving coil L1.Implanting the energy of member launches with the frequency of 25kHz in this particular case.Energy balance output signal is present in test point Y1.

The multiple embodiment that it will be understood by those skilled in the art that system above can combine in a lot of different modes.For example, the electric switch 1006 of Fig. 3 can be in Fig. 6-12 arbitrarily embodiment be combined, the hydraulic valve mobile device 1014 of Fig. 6 can be combined with the embodiment of Fig. 5, and change speed gear box 1024 can be combined with the embodiment of Fig. 4.Note that switch can refer to any electronic circuit or components and parts simply.

Determined method and system with reference to Figure 17,19 and 20 embodiment that describe, for control by wireless energy be transmitted into can be electrically operated the energy expenditure member implanted of apparatus.Such method and system will be in below briefly definition.

Supplying method thus, for controlling the transmitting of the wireless energy of supplying with the energy expenditure member that above-mentioned apparatus implants.Wireless energy E is from being positioned at the exterior source of energy transmitting patient body, and received by the internal energy receptor that is positioned at patient body, internal energy receptor is connected with the energy expenditure member that apparatus is implanted, for the energy directly or indirectly receiving to the supply of energy expenditure member.Determine internal energy receptor receive energy and for the balance between the energy of apparatus.Then the energy balance based on definite, controls the transmitting from the wireless energy E of exterior source of energy.

The wireless energy inductively primary coil from exterior source of energy is transmitted into the secondary coil in internal energy receptor.Can survey the change of the energy balance, with the transmitting of change control wireless energy of the energy balance based on surveying.Can also survey energy that internal energy receptor receives and for the difference between the energy of armarium, with the transmitting of energy difference control wireless energy based on surveying.

In the time controlling energy transmitting, if changing, the energy balance of surveying shows that the energy balance is increasing, the emission measure of wireless energy can reduce, or vice versa.Minimizing/the increase of energy transmitting can be further corresponding to the change speed of surveying.

If the energy difference of surveying shows the energy receiving and be greater than the energy of use, the emission measure of wireless energy can further reduce, or vice versa.Minimizing/the increase of energy transmitting can be then corresponding to other numerical value of energy difference of surveying.

As mentioned above, can consume for the energy of armarium with operation armarium, and/or can be by the stored energy for armarium at least one energy storage device at armarium.

In the time of definite electricity of armarium and/or physical parameter and/or patient's physiological parameter, can be used for the energy that consumes and store according to the emission rate transmitting of unit interval, the emission rate of unit interval is determined based on described parameter.The energy total amount of transmitting also can be determined based on described parameter.

Difference between the energy total amount and energy total amount consumption and/or storage that detect the reception of internal energy receptor, and when the difference detecting is relevant to the electrical quantity of at least one measurement (relevant with the described energy balance) integration in time, can determine this integration, for monitored voltage and/or the electric current relevant to the energy balance.

In the time that the electrical quantity of measuring (relevant to the amount of energy consuming and/or store) derivative is in time determined, this derivative can be defined as for monitored voltage and/or the electric current relevant to the energy balance.

In order to control the transmitting from the wireless energy of exterior source of energy, can by electric pulse from the first applications of electronic circuitry in exterior source of energy with transmitting wireless energy, electric pulse has forward position and tailing edge, the length of the length at very first time interval between forward position and the tailing edge in succession of change electric pulse and/or the second interval between the tailing edge in succession of electric pulse and forward position, and transmitting wireless energy, the wireless energy of transmitting is produced by the electric pulse of the vicissitudinous power of tool, and the length of the first and/or second interval is depended in the variation of power.

In this case, in the time of change first and/or the second interval, the frequency of electric pulse can be substantially invariable.In the time using electric pulse, electric pulse can remain unchanged, except changing the first and/or second interval.In the time of change first and/or the second interval, the amplitude of electric pulse can be substantially invariable.In addition, only, by the length at the very first time interval between forward position and the tailing edge in succession of change electric pulse, just can change electric pulse.

The sequence of two or more electric pulses can be provided in a line, wherein in the time using pulse train, described sequence has the first electric pulse at the section start of pulse train, and there is the second electric pulse at the termination of pulse train, two or more pulse train can be provided in a line, and wherein the length of the second interval between tailing edge (the second electric pulse in the first pulse train) and forward position (the first electric pulse in the second pulse train) is in succession changed.

In the time using electric pulse, electric pulse can have substantially invariable electric current and substantially invariable voltage.Electric pulse can also have substantially invariable electric current and substantially invariable voltage.In addition, electric pulse can also have substantially invariable frequency.Electric pulse in pulse train can similarly have substantially invariable frequency.

The circuit being made up of the first electronic circuit and exterior source of energy can have First Characteristic time cycle or very first time constant, and in the time effectively changing the energy of transmitting, such frequency time cycle can be within the scope of First Characteristic time cycle or time constant or is shorter.

Also provide thus the system that comprises above-mentioned apparatus, for controlling the transmitting of wireless energy of supplying with the energy expenditure member that apparatus implants.In the most wide in range meaning, system comprises control appliance and implantable internal energy receptor, control appliance is for controlling the transmitting from the wireless energy of energy transmitter, internal energy receptor is for receiving launched wireless energy, internal energy receptor is connected with the implantable energy expenditure member of apparatus, for the energy receiving to the supply of energy expenditure member directly or indirectly.System further comprises definite equipment, described definite equipment is suitable for determining the energy balance between the energy of internal energy receptor reception and the energy of the implantable energy expenditure member use of apparatus, wherein, based on definite definite energy balance of equipment, described control appliance control is from the transmitting of the wireless energy of external energy transmitter.

In addition, system can comprise following arbitrary content:

Primary coil in-exterior source of energy, is suitable for inductively launching wireless energy to the secondary coil in inner energy receiver.

-determine that equipment is suitable for surveying the change of the energy balance, and the transmitting of the change control wireless energy of the energy balance of control appliance based on detecting.

-determine that equipment is suitable for surveying the difference between the energy of internal energy receptor reception and the energy of the implantable energy expenditure member use of apparatus, and the transmitting of the energy balance control wireless energy of control appliance based on detecting.

If the change of-the energy balance that detects shows the energy balance increasing, control appliance control external energy transmitter reduces the emission measure of wireless energy, or vice versa, and wherein minimizing/the increase of energy transmitting is corresponding to the change speed detecting.

If-the energy difference that detects shows the energy receiving and is greater than the energy of use, control appliance control external energy transmitter reduces the emission measure of wireless energy, or vice versa, wherein minimizing/the increase of energy transmitting is corresponding to described other amplitude of the energy difference detecting.

-consume for the energy of apparatus to operate described apparatus, and/or by the stored energy for described apparatus at least one energy storage device at apparatus.

-in electricity and/or the physical parameter of determining apparatus, and/or in the situation of patient's physiological parameter, according to the emission rate of unit interval, the energy of energy transmitter transmitting for consuming and storing, the emission rate of unit interval is by determining that equipment is definite based on described parameter.Based on described parameter, determine the also total amount of the energy of definite transmitting of equipment.

-when the difference detecting between energy total amount energy total amount and consumption and/or that store that internal energy receptor receives, and when the difference detecting is relevant to the electrical quantity of at least one measurement (relevant with the energy balance) integration in time, determine that equipment determines this integration, for monitored voltage and/or the electric current relevant to the energy balance.

-in the time that the electrical quantity of measuring (relevant to the amount of energy consuming and/or store) derivative is in time determined, determine that equipment is defined as this derivative for monitored voltage and/or the electric current relevant to the energy balance.

-energy transmitter is included in the coil that human external is placed, and electronic circuit is set, with electric pulse to external coil energy supply with transmitting wireless energy.Electric pulse has forward position and tailing edge, and electronic circuit is suitable for changing very first time interval (between forward position and tailing edge in succession) and/or second interval (between tailing edge and forward position in succession) of electric pulse, to change the power of wireless energy of transmitting.Therefore, receive the vicissitudinous power of energy receiver tool of the wireless energy of transmitting.

-electronic circuit is adapted to transmit electric pulse, so that it remains unchanged except changing the first and/or second interval.

-electronic circuit has time constant, and is suitable for only in the scope of very first time constant, changing the first and second intervals, thereby in the time that the length of the first and/or second interval changes, the power of launching by coil is changed.

-electronic circuit is suitable for transmitting electric pulse, and described electric pulse only changes by changing very first time interval (between electric pulse forward position and tailing edge in succession).

-electronic circuit is suitable for providing the sequence of two or more electric pulses in a line, and described sequence has the first electric pulse at pulse train section start, also has the second electric pulse at pulse train termination, and

The length of the second interval between-tailing edge (the second electric pulse in the first pulse train) and forward position (the first electric pulse in the second pulse train) is in succession changed by the first electronic circuit.

-electronic circuit is suitable for providing electric pulse, and described pulse has substantially invariable height and/or amplitude and/or intensity and/or voltage and/or electric current and/or frequency.

-electronic circuit has time constant, and is suitable for only in the scope of very first time constant, changing the first and second intervals, thereby in the time that the length of the first and/or second interval changes, is changed by the power of the first coil transmitting.

-electronic circuit is suitable for providing electric pulse, described electric pulse only changes the length of the first and/or second interval in a certain scope, this scope comprises very first time constant, or compared with the numerical value of very first time constant, this scope approaches very first time constant relatively.

Figure 21-24 show the block diagram to four of implantation instrument energy supply of the present invention kinds of distinct methods with hydraulic way or pneumatic mode in further detail.

Figure 21 shows system as above.System comprises the apparatus 10 of implantation and other independently adjusting container 1013, one-way pump 1009 and reversal valve 1014.

Figure 22 shows apparatus 10 and fluid container 1013.Regulate wall of a container by movement, or change its size with any other different modes, can without any valve in the situation that, regulate apparatus, can make fluid freely pass through by the wall of mobile containers at any time.

Figure 23 shows apparatus 10, two-way pump 1009 and regulates container 1013.

Figure 24 shows the block diagram with the reverse servosystem of the first closed-system, described first closed-system control the second closed-system.Servosystem comprises adjusting container 1013 and servo container 1050.Via mechanical connection 1054, servo container 1050 is mechanically controlled the apparatus 10 of implanting.Described apparatus has expandable/contractile chamber.By the scalable container 1052 from larger (being connected with apparatus 10 fluids) supplying hydraulic fluid, preferably expanded in this chamber or shrink.Selectively, chamber comprises compressible gas, and it can compressed and expansion under the control of servo container 1050.

Servo container 1050 can be a part for apparatus itself.

In one embodiment, regulate container to be placed on patient subcutaneous, and operate by its outer surface of finger presses.Figure 25 a-c shows this system.In Figure 25 a, flexible subcutaneous adjusting container 1013 is shown as by conduit 1011 and is connected with the servo container 1050 that protrudes shape.The servo container 1050 of this bellows shape is included in flexible instrument 10.In the state shown in Figure 25 a, servo container 1050 comprises minimum fluid, and most fluid is in regulating container 1013.Due to the mechanical connection between servo container 1050 and apparatus 10, the external shape of apparatus 10 is dwindled, and its space occupying is less than its maximum volume.This maximum volume is represented by dotted lines in the drawings.

In the state shown in Figure 25 b, user (patient of for example implantation instrument) presses and regulates container 1013, make to be included in flow through conduit 1011 flow into servo container 1050, servo container 1050 (relying on the shape of its bellows) Longitudinal Extension of fluid wherein.Described expansion and then apparatus 10 is expanded, makes it occupy its maximum volume, the deferent duct (not shown) in the ampulla downstream that compressing is in contact with it thus.

Regulate container 1013 to be provided preferably with device 1013a, for keep its shape after compression.Equally, in the time of user's release regulation container, this device (schematically illustrating in the drawings) remains on elongation state by apparatus 10 thus.Like this, regulate container to be operating as in essence closure for system/open switch.

Referring now to Figure 26 and 27a-c, hydraulic pressure or the pneumatically-operated embodiment of selection are described.Block diagram shown in Figure 26 comprises the first closed-system of controlling the second closed-system.The first system comprises adjusting container 1013 and servo container 1050.Via mechanical connection 1054, servo container 1050 is mechanically controlled larger scalable container 1052.By from the hydraulic fluid supply of (being connected with apparatus 10 fluids) of described larger scalable container 1052, there is the implantation instrument 10 in expandable/contractile chamber and then controlled by described larger scalable container 1052.

The example of this embodiment is described referring now to Figure 27 a-c.As embodiment above, regulate container to be placed on patient subcutaneous, and operate by its outer surface of finger presses.Regulate container 1013 to be connected with servo container 1050 fluids of bellows shape by conduit 1011.In the first closed-system 1013,1011,1050 shown in Figure 31 a, servo container 1050 comprises minimum fluid, and most fluid is in regulating container 1013.

Servo container 1050 is mechanically connected with larger scalable container 1052, and in this example, scalable container also has the shape of bellows, but larger than the diameter of servo container 1050.Described larger scalable container 1052 is connected with apparatus 10 fluids.This means when user presses and regulate container 1013, while moving fluid from adjusting container 1013 to servo container 1050 thus, the expansion of servo container 1050 is shifted from described larger scalable container 1052 fluid that makes more volume to apparatus 10.In other words,, in this reverse servo, with the small size of larger power squeeze adjustments container, and this causes the displacement of the larger gross area with power less in unit are.

As the embodiment describing above with reference to Figure 25 a-c, regulate container 1013 to be provided preferably with device 1013a, for keep its shape after compression.Equally, in the time of user's release regulation container, this device (schematically illustrating in the drawings) remains on elongation state by apparatus 10 thus.Like this, regulate container to be operating as in essence the conduction and cut-off switch for system.

Claims

1. for obtaining a provisional sterile male contraceptive apparatus for boar individuality, comprising:

Implantable restraint device, described restraint device is suitable for the downstream area constraint deferent duct at ampulla within the controlled phase, and described equipment can stop sperm to arrive urethra thus, and wherein said restraint device comprises compressing equipment, and

Control appliance, described control appliance is for controlling the operation of described restraint device.

2. apparatus according to claim 1, described compressing equipment is used at least a portion of the deferential tissue wall of oppressing ampulla downstream, to stop flowing in deferent duct.

3. apparatus according to claim 2, wherein said compressing equipment is adjustable, and further comprises that operating equipment, described operating equipment are used for operating described adjustable compressing equipment, to change the compressing of deferential wall portion.

4. apparatus according to claim 3, wherein said operating equipment mechanically operates described compressing equipment.

5. apparatus according to claim 3, wherein said operating equipment operates described compressing equipment with hydraulic way.

6. apparatus according to claim 3, wherein said operating equipment operates described compressing equipment with non-magnetic and/or non-manual mode.

7. apparatus according to claim 3, wherein said operating equipment comprises electric operating equipment.

8. apparatus according to claim 7, wherein said operating equipment comprises motor.

9. apparatus according to claim 8, wherein said operating equipment comprises servosystem.

10. apparatus according to claim 4, wherein said compressing equipment comprises at least two elongated intermediate plate elements, on the flow direction of described intermediate plate element in deferent duct, on deferential not homonymy, extend along deferent duct, and described operating equipment operates described intermediate plate element to deferential wall portion is clamped between intermediate plate element, thereby oppress described wall portion.

11. apparatuses according to claim 5, wherein said operating equipment comprises hydraulic means and reverse servo, described hydraulic means is for regulating described compressing equipment with hydraulic way, and described reverse servo is operatively connected with described hydraulic means.

12. apparatuses according to claim 5, wherein said compressing equipment is mechanical pressure equipment, and described operating equipment comprises hydraulic means, described hydraulic means regulates described mechanical pressure equipment with hydraulic way.

13. apparatuses according to claim 1, wherein said restraint device comprises stimulation apparatus, described stimulation apparatus is for stimulate the wall portion of deferential tissue wall in the region in ampulla downstream, so that described wall portion shrinks, thereby affect mobile in deferent duct.

14. apparatuses according to claim 13, stimulation apparatus described in wherein said control appliance control, in response to the functional parameter of the male contraceptive apparatus detecting or the patient's that detects physiological parameter, regulate the stimulus intensity of wall portion.

15. apparatuses according to claim 13, wherein said control appliance is with stimulation apparatus described in first mode control, so that hard pressed wall portion is stimulated, thereby further retrain but do not stop flowing in deferent duct, and described control appliance is with stimulation apparatus described in the second pattern control, to suspend the stimulation to described wall portion, thereby increase flowing in deferent duct.

16. apparatuses according to claim 15, wherein stimulation apparatus described in the described control appliance control in the second pattern, to suspend the stimulation to described wall portion, thereby recovers flowing in deferent duct.

17. apparatuses according to claim 13, stimulation apparatus described in wherein said control appliance control, to stimulate hard pressed wall portion, thereby causes that described wall portion shrinks, and makes to stop flowing in deferent duct.

18. apparatuses according to claim 13, wherein said control appliance is with stimulation apparatus described in first mode control, so that hard pressed wall portion is stimulated, thereby flowing in prevention deferent duct, and described control appliance is with stimulation apparatus described in the second pattern control, to suspend the stimulation to described wall portion, thereby allow flowing in deferent duct.

19. apparatuses according to claim 18, wherein stimulation apparatus described in the described control appliance control in the second pattern, to suspend the stimulation to described wall portion, and controls described compressing equipment, to discharge described wall portion, thereby recovers flowing in deferent duct.

20. apparatuses according to claim 18, stimulation apparatus described in wherein said control appliance control, in response to the patient's who detects physiological parameter, regulate the stimulus intensity of wall portion.

21. apparatuses according to claim 18, stimulation apparatus described in wherein said control appliance control, in response to the functional parameter of the male contraceptive apparatus detecting, regulate the stimulus intensity of wall portion.

22. apparatuses according to claim 19, stimulation apparatus described in wherein said control appliance control, to increase the stimulus intensity of wall portion, makes to occur in deferent duct when pressure increases, to keep stoping flowing in deferent duct.

23. apparatuses according to claim 20, further comprise sensor, described sensor for detection of with deferent duct in the physiological parameter of patient body of pressure correlation, wherein said control appliance is in response to stimulation apparatus described in the signal controlling from described sensor.

24. apparatuses according to claim 23, wherein said physiological parameter is the pressure in patient body, and described sensor is pressure transducer.

25. apparatuses according to claim 21, stimulation apparatus described in wherein said control appliance control, to increase in response to the pressure in the deferent duct detecting, increases the stimulus intensity of wall portion, makes mobile in deferent duct remain prevention.

26. apparatuses according to claim 25, further comprise sensor, described sensor for detection of with deferent duct in the physiological parameter of patient body of pressure correlation, wherein said control appliance is in response to stimulation apparatus described in the signal controlling from described sensor.

27. apparatuses according to claim 26, wherein said physiological parameter is the pressure in patient body, and described sensor is pressure transducer.

28. apparatuses according to claim 13, wherein said control appliance is controlled described stimulation apparatus from patient body.

29. apparatuses according to claim 28, wherein said control appliance can be operated by patient.

30. apparatuses according to claim 29, wherein said control appliance comprise can be manually operated for switching the switch of conducting and cut-off of described stimulation apparatus, described switch is suitable for the subcutaneous implantation to patient, so that manual operation from patient body.

31. apparatuses according to claim 29, wherein said control appliance comprises the exercisable manual wireless remote-cotnrolled device of patient, to switch conducting and the cut-off of described stimulation apparatus.

32. apparatuses according to claim 28, wherein said control appliance is with stimulation apparatus described in wireless mode control.

33. apparatuses according to claim 13, stimulation apparatus is intermittent and stimulate individually the zones of different of wall portion described in wherein said control appliance control, thereby at different time points, at least two described regions is stimulated.

34. apparatuses according to claim 33, described in wherein said control appliance control, stimulation apparatus intermittently stimulates the each region in the zones of different of described wall portion within period in succession, each period is enough short, to keep in time blood circulation satisfied in this region, until finish this period.

35. apparatuses according to claim 33, described in wherein said control appliance control, stimulation apparatus intermittently stimulates the region of described wall portion, thereby the blood circulation of normal, before stimulation apparatus stimulates this region again, is recovered if having time in the current unprovoked region of described wall portion.

36. apparatuses according to claim 13, stimulation apparatus once stimulates one or more regions of described wall portion described in wherein said control appliance control.

37. apparatuses according to claim 36, stimulation apparatus stimulates the zones of different of described wall portion in turn described in wherein said control appliance control.

38. apparatuses according to claim 36, stimulation apparatus moves on to another region from a region in time by stimulation described in wherein said control appliance control.

39. apparatuses according to claim 36, described in wherein said control appliance control stimulation apparatus with mobile phase in patient's deferent duct with or contrary direction on, will be to the stimulation that circulates of these regions along described wall portion.

40. apparatuses according to claim 36, stimulation apparatus, according to predetermined stimulation mode, launches to stimulate to these regions described in wherein said control appliance control.

41. apparatuses according to claim 13, stimulation apparatus is to change the stimulus intensity of described wall portion described in wherein said control appliance control.

42. according to the apparatus described in claim 41, and stimulation apparatus changes the stimulus intensity to described wall portion in a looping fashion described in wherein said control appliance control.

43. apparatuses according to claim 13, described in wherein said control appliance control stimulation apparatus by pulse interval the zones of different of described wall portion is stimulated.

44. according to the apparatus described in claim 43, and stimulation apparatus is with by pulse interval and individually these regions are stimulated described in wherein said control appliance control.

45. according to the apparatus described in claim 43, wherein said pulse shaping pulse train.

46. according to the apparatus described in claim 45, at least first area and second area in the region of wherein said wall portion carry out repetitive stimulation with the first pulse train and the second pulse train, and described the first pulse train and the second pulse train are relative to each other switched in time.

47. according to the apparatus described in claim 46, and wherein said first area stimulates with described the first pulse train, and described second area does not stimulate with described the second pulse train, and vice versa.

48. according to the apparatus described in claim 47, and wherein said the first pulse train and described the second pulse train are relative to each other switched, and described the first pulse train and described the second pulse train are overlapped each other at least in part.

49. according to the apparatus described in claim 45, and stimulation apparatus changes the amplitude of the pulse of pulse train described in wherein said control appliance control.

50. according to the apparatus described in claim 45, and stimulation apparatus is to change the idle period between the individual pulse of each pulse train described in wherein said control appliance control.

51. according to the apparatus described in claim 45, and stimulation apparatus is to change the width of each pulse of pulse train described in wherein said control appliance control.

52. according to the apparatus described in claim 45, and stimulation apparatus is to change the frequency of pulse of pulse train described in wherein said control appliance control.

53. according to the apparatus described in claim 45, and stimulation apparatus is to change the idle period between pulse train described in wherein said control appliance control.

54. according to the apparatus described in claim 53, described in wherein said control appliance control, stimulation apparatus will remain long enough the each idle period between pulse train, when not stimulated in the phase at one's leisure in described region, recover the blood circulation of normal in each region.

55. according to the apparatus described in claim 45, and stimulation apparatus is to change the length of each pulse train described in wherein said control appliance control.

56. according to the apparatus described in claim 45, and stimulation apparatus is to change the frequency of pulse train described in wherein said control appliance control.

57. according to the apparatus described in claim 45, and stimulation apparatus is to change the umber of pulse of each pulse train described in wherein said control appliance control.

58. apparatuses according to claim 13, wherein said stimulation apparatus intermittence and the independently zones of different of the wall portion to patient are carried out electricity irritation.

59. according to the apparatus described in claim 58, and wherein said stimulation apparatus stimulates patient's territory, wainscot wall area with electric pulse.

60. according to the apparatus described in claim 58, and wherein said wall portion comprises meat fiber, and described stimulation apparatus stimulates the wall portion that comprises meat fiber with electric pulse, to cause the contraction of meat fiber, thereby described wall portion is shunk.

61. according to the apparatus described in claim 58, and wherein said stimulation apparatus comprises at least one electric device, for engaging with described wall portion and for described wall portion being stimulated with electric pulse.

62. according to the apparatus described in claim 61, and wherein said stimulation apparatus comprises multiple electric devices.

63. according to the apparatus described in claim 62, and wherein said electric device is relative to each other placed with the orientation of fixing.

64. according to the apparatus described in claim 63, and wherein said stimulation apparatus comprises the structure of holding described electric device with described fixing orientation.

65. according to the apparatus described in claim 64, wherein said electric device forms the electric device of elongated pattern, and described structure can be used on patient's deferent duct, on the flow direction of the electric device that makes elongated pattern in deferent duct, extend along deferential wall portion, and described element is in abutting connection with the corresponding region of described wall portion.

66. according to the apparatus described in claim 61, and stimulation apparatus carries out electric excitation to described electric device described in wherein said control appliance control.

67. according to the apparatus described in claim 66, and stimulation apparatus is to encourage each electric device in a looping fashion by electric pulse described in wherein said control appliance control.

68. according to the apparatus described in claim 66, and stimulation apparatus encourages described electric device described in wherein said control appliance control, makes simultaneously multiple or organize electric device more and encourage.

69. according to the apparatus described in claim 66, and stimulation apparatus encourages described electric device described in wherein said control appliance control, make sequentially once to encourage an electric device, or randomly or according to predetermined way, actuated in sequence is organized electric device more.

70. according to the apparatus described in claim 66, wherein said electric device forms the electric device of elongated pattern, and described electric device can be used in patient's deferential wall portion, on the flow direction of the electric device that makes elongated pattern in deferent duct, along deferential wall portion longitudinal extension, and electric device is in abutting connection with the corresponding region of deferential wall portion.

71. according to the apparatus described in claim 70, and stimulation apparatus longitudinally encourages electric device in succession along the electric device of elongated pattern described in wherein said control appliance control.

72. according to the apparatus described in claim 71, wherein in the time that described stimulation apparatus is used on patient's deferent duct, stimulation apparatus encourages described electric device in the direction contrary or identical with flow direction in deferent duct in succession along the electric device of elongated pattern described in described control appliance control.

73. according to the apparatus described in claim 71, wherein in the time that described stimulation apparatus is used on patient's deferent duct, stimulation apparatus encourages described electric device towards the two ends of the electric device of elongated pattern from the position that is substantially positioned at compressing Bi Bu center in succession along the electric device of elongated pattern described in described control appliance control.

74. according to the apparatus described in claim 71, and stimulation apparatus encourages electric device described in wherein said control appliance control, makes the current electric device being energized form at least one group of adjacent electric device being energized.

75. according to the apparatus described in claim 74, and the electric device in the group of the electric device being wherein energized forms the path of the electric device being energized.

76. according to the apparatus described in claim 75, and wherein, in the time that described stimulation apparatus is used on deferent duct, extend around patient's deferent duct at least in part in the path of the electric device being energized.

77. according to the apparatus described in claim 75, and wherein, in the time that described stimulation apparatus is used on deferent duct, extend around patient's deferent duct completely in the path of the electric device being energized.

78. according to the apparatus described in claim 75, and wherein, in the time that described stimulation apparatus is used on patient's deferent duct, the electric device in the group of the electric device being energized forms two paths of the electric device being energized, and described two paths extend relative to one another.

79. according to the apparatus described in claim 78, wherein in the time that described stimulation apparatus is used on deferent duct, described two paths of the described electric device being energized extend in the deferential common side of patient, and at least basic transverse to the flow direction in patient's deferent duct.

80. according to the apparatus described in claim 66, and wherein in the time that described stimulation apparatus is used on deferent duct, described electric device forms multicomponent part, and these groups are formed on a series of groups that on the flow direction in patient's deferent duct, extend along patient's deferent duct.

81. apparatuses described in 0 according to Claim 8, wherein in the time that described stimulation apparatus is used on patient's deferent duct, stimulation apparatus described in described control appliance control, the many groups electric device in the direction contrary or identical with flow direction in deferent duct in to described a series of group encourages in succession.

82. apparatuses described in 0 according to Claim 8, wherein in the time that described stimulation apparatus is used on patient's deferent duct, stimulation apparatus described in described control appliance control, from being substantially positioned at the position at compressing Bi Bu center, the many groups electric device in the direction contrary and identical with flow direction in deferent duct in to described a series of group encourages in succession.

83. apparatuses described in 0 according to Claim 8, wherein, in the time that described stimulation apparatus is used on deferent duct, the electric device in every group of electric device forms the path of electric device, and extend around patient's deferent duct at least in part in described path.

84. apparatuses described in 3 according to Claim 8, wherein, in the time that described stimulation apparatus is used on deferent duct, extend around patient's deferent duct completely in the described path of the electric device in every group of electric device.

85. apparatuses described in 3 according to Claim 8, wherein, in the time that described stimulation apparatus is used on deferent duct, the electric device in every group of electric device forms two paths of electric device, in the deferential common side of patient, extends.

86. apparatuses described in 5 according to Claim 8, wherein, in the time that described stimulation apparatus is used on patient's deferent duct, described two paths of the electric device in every group of electric device extend transverse to the flow direction in deferent duct at least substantially.

87. apparatuses according to claim 13, wherein said stimulation apparatus carries out thermostimulation to described wall portion.

88. apparatuses described in 7 according to Claim 8, stimulation apparatus described in wherein said control appliance control, cooling so that the wall portion of compressing is carried out, thus cause the contraction of described wall portion.

89. apparatuses described in 8 according to Claim 8, stimulation apparatus described in wherein said control appliance control, cooling so that the wall portion of compressing is carried out, thus cause the contraction of described wall portion, make to retrain flowing in deferent duct.

90. apparatuses described in 8 according to Claim 8, stimulation apparatus described in wherein said control appliance control, cooling so that wall portion is carried out, thus cause the contraction of described wall portion, make constraint but do not stop flowing in deferent duct.

91. apparatuses described in 8 according to Claim 8, stimulation apparatus described in wherein said control appliance control, cooling so that wall portion is carried out, thus cause the contraction of described wall portion, make to stop flowing in deferent duct.

92. apparatuses described in 7 according to Claim 8, when stimulation apparatus is oppressed and is shunk in wall portion described in wherein said control appliance control to the heating of described wall portion, to cause the expansion of wall portion.

93. according to the apparatus described in claim 92, and wherein said wall portion comprises blood vessel, and described in described control appliance control, the cooling blood vessel of stimulation apparatus is so that it shrinks, or heating blood vessel is so that its expansion.

94. apparatuses described in 7 according to Claim 8, wherein said control appliance is controlled described stimulation apparatus from patient body.

95. according to the apparatus described in claim 94, and wherein said control appliance comprises the internal control unit in implantable patient body, and described internal control unit is used for controlling described stimulation apparatus.

96. according to the apparatus described in claim 95, and wherein said internal control unit is programmable.

97. according to the apparatus described in claim 95, and wherein said control appliance comprises the external control unit of design outside patient body, and described external control unit is used for controlling described compressing equipment and/or stimulation apparatus.

98. according to the apparatus described in claim 97, can be programmed by described external control unit in wherein said internal control unit.

99. according to the apparatus described in claim 98, and wherein said internal control unit is programmable, for controlling in time described compressing equipment and/or stimulation apparatus.

100. according to the apparatus described in claim 99, and described compressing equipment, according to activity scheduling program, is controlled in time in wherein said internal control unit.

101. according to the apparatus described in claim 99, and wherein said internal control unit comprises microprocessor.

102. apparatuses according to claim 13, further comprise at least one implantable sensor, and wherein said control appliance or described stimulation apparatus are in response to the signal from described sensor.

103. according to the apparatus described in claim 102, and wherein said sensor detects at least one physiological parameter of patient directly or indirectly.

104. according to the apparatus described in claim 102, and wherein said sensor comprises pressure transducer, detects as physiological parameter for the pressure in patient body.

105. according to the apparatus described in claim 104, and compressing equipment and/or stimulation apparatus described in wherein said control appliance control, to change the compressing to patient's wall portion in response to described pressure transducer detects predetermined measured pressure value.

106. according to the apparatus described in claim 102, and wherein said control appliance comprises implantable internal control unit, and in response to the signal from described sensor, described compressing equipment and/or stimulation apparatus are directly controlled in described internal control unit.

107. according to the apparatus described in claim 102, and wherein said control appliance comprises the external control unit outside patient body, and in response to the signal from described sensor, described external control unit is used for controlling described compressing equipment and/or stimulation apparatus.

108. according to the apparatus described in claim 102, and wherein said control appliance produces instruction in response to the signal from described sensor.

109. according to the apparatus described in claim 108, and wherein said instruction comprises the information of acoustical signal or demonstration.

110. apparatuses according to claim 11, wherein said reverse servo comprises at least two implantable containers, described container comprises hydraulic fluid.

111. according to the apparatus described in claim 110, wherein said reverse servo comprise can subcutaneous implantation first regulate container.

112. according to the apparatus described in claim 111, and wherein said reverse servo further comprises implantable the second servo container.

113. according to the apparatus described in claim 112, and wherein said servo container is connected with described adjusting fluid container.

114. according to the apparatus described in claim 112, and wherein said servo container is directly controlled expansion and/or the contraction of described compressing equipment.

115. according to the apparatus described in claim 112, wherein said servo container is controlled expansion and/or the contraction of described compressing equipment indirectly, wherein said reverse servo further comprises the 3rd container, described the 3rd container is suitable for implanting abdominal part or retroperitoneum or pelvis area, and be operatively connected with described servo container, for the hydraulic fluid of mobile described the 3rd container, thereby to compressing operate.

116. according to the apparatus described in claim 115, and wherein said the 3rd container has than the larger volume of described the first container.

117. according to the apparatus described in claim 115, and wherein said the 3rd container is communicated with described compressing equipment fluid.

118. according to the apparatus described in claim 115, and wherein said servo container is with the 3rd container described in mechanical connection control.

119. one kinds for obtaining the provisional sterile system of boar individuality, comprises apparatus according to claim 1.

120. according to the system described in claim 119, further comprises the switch at least one implantable patient body, controls described apparatus for manual and non-intervention.

121. according to the system described in claim 119, further comprise hydraulic test, described hydraulic test has implantable hydraulic container, described hydraulic container is connected with hydraulic way with described apparatus, wherein said apparatus is suitable for regulating by pressing described hydraulic container non-interventionly, to operate described compressing equipment.

122. according to the system described in claim 119, further comprises wireless remote controller, controls described apparatus for non-intervention.

123. according to the system described in claim 122, wherein said wireless remote controller comprises at least one external signal emitter and/or receptor, further comprise internal signal receptor and/or emitter in implantable patient body, for receiving the signal of described external signal emitter transmitting, or transmit to described external signal receptor.

124. according to the system described in claim 122, and wherein said wireless remote controller is launched at least one for controlling the wireless control signal of described apparatus.

125. according to the system described in claim 124, and wherein said wireless control signal comprises frequency modulation, amplitude modulation or phase-modulated signal or their combination.

126. according to the system described in claim 124, and wherein said wireless remote controller transmitting electromagnetic carrier wave signal, for carrying described control signal.

127. according to the system described in claim 119, further comprises wireless energy transmitter, the implantable energy expenditure member of described apparatus is encouraged with wireless energy for non-intervention.

128. according to the system described in claim 127, wherein said wireless energy comprises ripple signal, and described ripple signal is selected from: acoustic signals, ultrasonic signal, infrared signal, visible light signal, ultraviolet signal, laser signal, microwave signal, radio wave signal, x x radiation x signal and gamma radiation signal.

129. according to the system described in claim 127, and wherein said wireless energy comprises one of following content: the Electric and magnetic fields of electric field, magnetic field, combination.

130. according to the system described in claim 124, and wherein said control signal comprises one of following content: the Electric and magnetic fields of electric field, magnetic field, combination.

131. according to the system described in claim 128, and wherein said signal comprises the combination of analogue signal, digital signal or analog and digital signal.

132. according to the system described in claim 119, further comprises implantable internal energy source, encourages for the implantable energy expenditure member to described apparatus.

133. according to the system described in claim 132, further comprises exterior source of energy, and for wireless mode transmission of power, can be charged with wireless mode by the energy of described transmission in wherein said internal energy source.

134. according to the system described in claim 133, further comprise sensor and feedback device, described sensor measuring ability parameter, described functional parameter is to relevant for the power transfer of being charged in described internal energy source, described feedback device for from patient body to external transmission feedback information, described feedback information is relevant with the functional parameter of described sensor detection.

135. according to the system described in claim 119, further comprises feedback device, in patient body to external transmission feedback information, described feedback information and at least one physiological parameter of patient and relevant functional parameter is relevant with described apparatus.

136. according to the system described in claim 119, further comprise sensor and implantable internal control unit, for control described apparatus in response to information, the patient's that described information detects with described sensor physiological parameter and the detection of described sensor relevant about at least one in the functional parameter of described apparatus.

137. according to the system described in claim 136, and wherein said physiological parameter is pressure or motion.

138. according to the system described in claim 119, further comprise external data communication device and the implantable internal data communicator of communicating by letter with described external data communication device, wherein said internal data communicator is fed to the data relevant to described apparatus or patient to described external data communication device, and/or described external data communication device is to described internal data communicator data feed.

139. according to the system described in claim 119, further comprises motor or pump, for operating the restraint device of described apparatus.

140. according to the system described in claim 119, further comprises Hydraulically Operated Equipment, for operating the restraint device of described apparatus.

141. according to the system described in claim 119, further comprise operating equipment, for operating the restraint device of described apparatus, wherein said operating equipment comprises servo control mechanism, described servomechanism design is to reduce the required power of described operating equipment to operate described apparatus, make on the contrary the longer stroke of described operating equipment effect, increase the time for definite action.

142. according to the system described in claim 127, further comprise operating equipment, be used for operating described apparatus, wherein in the time that described wireless energy is just launched by described energy transmitter, described wireless energy uses in its wireless status, with operating equipment described in direct-drive, thereby produce the kinetic energy for the operation of described apparatus.

143. according to the system described in claim 127, further comprises energy conversion, for the energy that is the second form from the first formal transformation by the wireless energy of described energy transmitter transmitting.

144. according to the system described in claim 143, wherein, in the time of energy that described energy conversion is the second form by the power conversion of the first form of described energy transmitter transmitting, described energy conversion directly carries out energy supply with the energy of the second form to the implantable energy expenditure member of described apparatus.

145. according to the system described in claim 143, the energy of wherein said the second form comprise unidirectional current and alternating current at least one of them.

146. according to the system described in claim 143, further comprises implantable accumulator, and the energy of wherein said the second form is at least in part for to described charge in batteries.

147. according to the system described in claim 143, and the energy of wherein said the first form or the second form comprises one of them kind of following energy: magnetic energy, kinetic energy, acoustic energy, chemical energy, electromagnetic energy, luminous energy, nuclear energy, heat energy.

148. according to the system described in claim 119, further comprises implantable electric components, and described electric components comprises at least one voltage level limiter and/or at least one constant current limiter.

149. according to the system described in claim 143, further comprise the second control appliance and implantable internal energy receptor, described the second control appliance is for controlling the transmitting from the wireless energy of described energy transmitter, described internal energy receptor is for receiving the wireless energy of transmitting, described internal energy receptor is connected with the implantable energy expenditure member of described apparatus, for the energy receiving to described implantable energy expenditure member supply directly or indirectly, described system further comprises definite equipment, described definite equipment is suitable for determining the energy balance between the energy of described internal energy receptor reception and the energy of the implantable energy expenditure member use of described apparatus, wherein based on the definite energy balance of described definite equipment, described the second control appliance control is from the transmitting of the wireless energy of external energy transmitter.

150. according to the system described in claim 149, and wherein said definite equipment is suitable for surveying the change in the described energy balance, and described the second control appliance changes based on the energy balance detecting, and controls the transmitting of wireless energy.

151. according to the system described in claim 149, wherein said definite equipment is suitable for surveying energy that described internal energy receptor receives and for the difference between the energy of the implantable energy expenditure member of described apparatus, and the energy difference of described the second control appliance based on detecting controlled the transmitting of wireless energy.

152. according to the system described in claim 127, wherein said energy transmitter comprises the coil being placed on outside human body, further comprise the implantable energy receiver that will be placed in human body and the electronic circuit of connection, described electronic circuit encourages outside coil with electric pulse, with transmitting wireless energy, described electric pulse has forward position and tailing edge, described electronic circuit is suitable for changing the second interval between very first time interval and/or electric pulse tailing edge and the forward position in succession between electric pulse forward position and tailing edge in succession, to change the power of the wireless energy of launching, described energy receiver receives the wireless energy of transmitting, described wireless energy has the power of change.

153. according to the system described in claim 152, and wherein said electronic circuit is adapted to transmit described electric pulse, so that described electric pulse remains unchanged except changing very first time interval and/or the second interval.

154. according to the system described in claim 152, wherein said electronic circuit has time constant, and described electronic circuit is suitable for only in the scope of very first time constant, changing very first time interval and the second interval, thereby in the time that the length of very first time interval and/or the second interval changes, the power of launching by coil is changed.

155. according to the system described in claim 135, further comprise implantable internal energy receptor for receiving wireless energy and for launching the external energy emitter of wireless energy, described energy receiver has inner the first coil and the first electronic circuit being connected with described the first coil, described energy emitter has outside the second coil and the second electronic circuit being connected with described the second coil, the outside second coil transmitting wireless energy of wherein said energy emitter, described wireless energy is received by the first coil of described energy receiver, described system further comprises for switching inner the first coil and the conducting being connected of the first electronic circuit and the on and off switch of cut-off, make in the time that described on and off switch switches the conducting being connected of inner the first coil and the first electronic circuit and cut-off, the feedback information relevant to the charging of the first coil is by external energy transmitter receipt, reception form is that the load impedance of outside the second coil changes.

156. according to the system described in claim 135, further comprise implantable internal energy receptor for receiving wireless energy and for launching the external energy emitter of wireless energy, described energy receiver has inner the first coil and the first electronic circuit being connected with described the first coil, described energy emitter has outside the second coil and the second electronic circuit being connected with described the second coil, the outside second coil transmitting wireless energy of wherein said energy emitter, described wireless energy is received by the first coil of energy receiver, described system further comprises the feedback device for outwards transmitting the energy quantities received of the first coil as feedback information, and wherein the second electronic circuit comprises definite equipment, be used for receiving described feedback information, and for power transfer amount and the feedback information of the second coil are compared, to obtain the degree of coupling between the first coil and the second coil, described feedback information is relevant to the energy quantities received of the first coil.

157. according to the system described in claim 156, and wherein said energy emitter, in response to the degree of coupling obtaining, regulates the energy of transmitting.

158. according to the system described in claim 156, and the second coil of its peripheral is suitable for moving with respect to the first coil of inside, and to set up the optimal location of the second coil, in this position, the degree of coupling is maximized.

159. according to the system described in claim 158, and the second coil of wherein said outside is suitable for calibrating the transmission quantity of energy, to obtained the feedback information in described definite equipment before the degree of coupling is maximized.

160. according to the system described in any one in claim 119 to 159, and wherein said apparatus is according to the apparatus described in any one in claim 110 to 118.