CN102395330A - A heart valve - Google Patents
A heart valve Download PDFInfo
- Publication number
- CN102395330A CN102395330A CN2010800097454A CN201080009745A CN102395330A CN 102395330 A CN102395330 A CN 102395330A CN 2010800097454 A CN2010800097454 A CN 2010800097454A CN 201080009745 A CN201080009745 A CN 201080009745A CN 102395330 A CN102395330 A CN 102395330A
- Authority
- CN
- China
- Prior art keywords
- support
- cardiac valve
- valve
- sleeve
- stent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0482—Needle or suture guides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0483—Hand-held instruments for holding sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
Abstract
A heart valve (1 ) is provided in which a valve member including a plurality of valve leaflets (12) secured together is secured within a stent (2). The leaflets are made of a biologic material that has a maximum thickness of 0.3 mm. Suitably treated kangaroo tissue such as that treated using the ADAPTTM technology is considered appropriate. Each leaflet preferably has an arcuate shaped side (18) for attachment to the stent. The resultant crimped stent may have a maximum diameter of about 7.5 or even 7.0 mm. Preferably, a sleeve (6) made of a porous, biocompatible material extends about the outer surface of the stent, along at least a part, and typically all of its length. Preferably, the stent is configured to initially expand at both ends (8, 9), this being conveniently achieved by using a stent in the form of a mesh defined by interconnected struts with the struts in a central region being stronger than the struts in the end regions.
Description
Technical field
The present invention relates to a kind of artificial heart replacement valve.
Background technology
It is well-known substituting cardiac valve with the artificial valve.A kind of cardiac valve of form comprises the valve that is positioned at collapsible webmaster or support.Support provides with folded state, and is inserted in the body through blood vessel or tremulous pulse usually.In case support is in place, just utilize inflatable balloon to expand.Valve is through the frictional force fix in position between autologous tissue and the support.After several weeks, valve becomes more fixing through ingrown tissue.Yet before tissue ingrowth, initial valve implantation is the problem that the valve of these types is paid close attention to.Cardiac valve is fixed in the heart valve annulus in the body valve usually.In this case, they keep opening and avoid removing the needs from the body valve from the body valve.
Use this cardiac valve usually a problem of experience be, before valve is by balloon expandable, exist limited space to be used to be in the introducing of the valve of folding or rolled state.
In addition; Valve member generally includes three flexible flaps leaves (perhaps for certain applications; They are called as cusp sometimes, but under the situation of not considering application facet, are referred to as the lobe leaf in this article), these three flexible flaps leaves connect to form triangle along their sidepiece.The structure of these lobe leaves is always best, and habitual material do not show the required characteristic of extensive use, such as wearability and anticalcium voltinism.
Owing to there is not direct visual position, therefore the accurate location of this valve also is difficult, and this has to utilize fluorescence imaging to realize indirectly usually.
And, in the seepage that blood can take place between support and the heart valve annulus or between support and tremulous pulse or the blood vessel surface.
Goal of the invention
The objective of the invention is to make a kind of cardiac valve, this cardiac valve will be alleviated one or more in the problems referred to above at least in part.
Summary of the invention
According to the present invention, a kind of cardiac valve is provided, this cardiac valve comprises the valve member that is fixed in the support, valve member comprises a plurality of lobe leaves that are fixed together, valvular being characterised in that, the lobe leaf is that the biomaterial of 0.3mm is processed by maximum ga(u)ge.
Additional features of the present invention is that biomaterial has the maximum ga(u)ge of 0.25mm; Each lobe leaf has arciform sidepiece, is preferably to be roughly parabola shaped sidepiece, to be attached on the support; Support has the maximum gauge of 7.5mm under its state that curls, and preferably has the maximum gauge of about 7mm; Biomaterial is the kangaroo tissue of suitably handling (kangaroo tissue); And this kangaroo tissue is the ADAPT of the Celxcel company limited (BioMD company limited) (Celxcel Pty Limited (BioMD Limited) of Perth, Western Australia) that utilizes Perth city, Western Australia
TMThe tissue of technical finesse.
The present invention also provides the sleeve of being processed by porous biocompatible material, and said sleeve extends along the length of support around the outer surface of support at least in part.Telescopic material preferably is selected from porous polyester and expanded ptfe (PTFE), preferably ultra-thin porous polyester.Sleeve can extend on the length of support, and sleeve has the thickness of 0.1mm to 0.5mm usually, preferably has the thickness of 0.2mm.Sleeve can be fixed on the support through the common suture that extends along its each end.
The present invention also provides a kind of cardiac valve; This cardiac valve comprises the valve member that is fixed in the expandable stent; This support has two ends and central area; Valve member comprises a plurality of lobe leaves that are fixed together, valvular being characterised in that, and support is configured at first expand at its place, two ends.
Other of this aspect of the present invention are characterised in that the form of support is the net that is limited on interconnective pillar; Particularly firmer than the pillar of end regions through the pillar that makes the central area, usually the cross section of the pillar through making the central area is more bigger, makes the material of support be reinforced in the central area; Support is processed by cochrome (MP25N).
The present invention also provides a kind of being used for that valve member is sewn into the instrument on the support, and this instrument comprises a pair of microscler clamp, and each clamp has the slit that extends along the part of the length of clamp.
Additional features of the present invention is to have the arc notch of array of spaced at least one side of each slit.
In order to understand above-mentioned and other characteristics of the present invention more fully, will describe one embodiment of the present of invention with reference to accompanying drawing now.
Description of drawings
In the accompanying drawings:
Fig. 1 is valvular axonometric chart;
Fig. 2 is the valvular side view among Fig. 1;
Fig. 3 is the axonometric chart that is used for the valvular support of Fig. 1;
Fig. 4 is the axonometric chart that is used for the valvular valve member of Fig. 1;
Fig. 5 is the side view that is used for the lobe leaf of the valve member shown in Fig. 4; And
Fig. 6 is the side view that is used for second embodiment of valvular support.
The specific embodiment
Cardiac valve (1) has been shown among Fig. 1 and Fig. 2, and cardiac valve (1) comprises tubular bracket (2), is fixed on tubular bracket (2) inner valve member (4) and outer sleeve (6).With reference to figure 3, support (2) forms for cylindrical shape and through a plurality of concentric diamond holes of length cut along cochrome (MP35N) pipe.Support (2) therefore has rhombus net outward appearance, and the end of support (2) (8,9) are zigzag.
Support (2) under the expansion state is shown, its medium-height trestle (2) have 20mm to the length between the 22mm and 23mm to the diameter between the 26mm.Yet, in the manufacturing of support (2), used the cobalt chromium alloy tube of diameter as 10mm.After cutting, this pipe is expanded, and valve member (4) and sleeve (6) are fixed on this pipe.The cardiac valve (1) of assembling then is crimped on the foley's tube (not shown) in a conventional manner.
Especially, with reference to figure 4 and Fig. 5, valve member is by three leaf one-tenth of lobe, and each lobe leaf is from using the ADAPT of Celxcel company limited
TMA slice kangaroo tissue of technical finesse downcuts.Each lobe leaf (12) has straight outlet sidepiece (14), has extension sidepiece (16) usually at the place, each end of straight outlet sidepiece (14), and each length of extending sidepiece (16) is about 1/3rd of the length of outlet sidepiece (14).Arc inlet sidepiece (18) extends between sidepiece (16) and is relative with outlet sidepiece (14).In this embodiment, inlet sidepiece (18) is parabola shaped.
Lobe leaf (12) is fixed together to form triangle through row's suture (20) along its sidepiece (16), and wherein, row's suture (20) a little inwardly is tapered towards outlet sidepiece (14) from inlet sidepiece (18) beginning of adjacency.
Subsequently, valve member (4) through along sidepiece (16,18) as in Fig. 5, being fixed in the support (2) by the shown suture of round dot (22).Should be understood that, the parabola shaped shape of the inlet sidepiece (18) of each lobe leaf (12) corresponding to the rake that passes support (2), wherein each lobe leaf (12) is fixed on the support (2) along this rake.
The use of the kangaroo tissue of having handled has many advantages.The first, this tissue is flexibility and wear-resistant.The second, therefore this tissue calcification can keep its flexibility over a long time.The 3rd, this tissue is tough and tensile relatively, therefore can be thinner than the many other materials that use in using at this.In this embodiment, each lobe leaf has the maximum ga(u)ge of 0.22mm.This characteristic of the kangaroo tissue of having handled is a particular importance; Because this characteristic can make whole cardiac valve be in its rolled state; In this rolled state; Cardiac valve has been ready to be introduced into human body, and valvular diameter is slightly less than other valvular diameters of present use.The use of kangaroo tissue can make curling cardiac valve have the diameter of 6.7mm [20French], and traditional of the prior art curling cardiac valve has the diameter of 8.0mm [24French].This has had significantly dimensionally and has reduced, and conceivable be that it will be convenient to the valvular initial placement of curling biglyyer.
The other key character of cardiac valve (1) is around the sleeve (6) of the outer surface setting of support (2).Sleeve is processed by porous biomaterial, is that the ultra-thin porous polyester of 0.2mm is processed by thickness in this embodiment.The end of sleeve (6) is consistent with the end of support (2) (8,9), along the suture (24,26) of each end (8,9) sleeve (6) is fixed on the support (2).Sleeve (6) is through being fixed to valve member (4) the further fix in position of suture on the support, and suture extends along the appropriate section of support and sleeve (6).
Sleeve (6) has two major functions.First function is for ingrown tissue provides porous surface, and after cardiac valve (1) was implanted, porous surface was assisted cardiac valve (1) fix in position.Second function is the resistance that increase is provided between cardiac valve and arterial wall, thereby holdout device moves after cardiac valve is implanted.Crucial is that sleeve also assists to prevent the blood leakage between cardiac valve (1) and the arterial wall.This has improved valvular effect greatly.
Yet, should be understood that, there are valvular many other the embodiment fall in the scope of the present invention.For example, any suitable material that comprises expansion PTFE may be used to sleeve.In this embodiment, all used the Corex suture, but can use other suitable materials arbitrarily for all sutures.Valve member also can have any suitable shapes.Support also can be processed by any suitable material, and can have any suitable shapes.
With reference to figure 6, support can be made such that the material of locating end (8,9) is thinner than the material that central authorities (30) locate.This will cause end regions in expansion process, at first to be expanded, so that support appears as by the waist shape shape shown in the dotted line.This shape will guarantee that cardiac valve becomes and in valve annulus, concentrate on the valve annulus centre easily that cardiac valve can further be fixed to the intra-annular appropriate location of valve before the inflation at air bag, to give support cylindrical shape more uniformly.This can come easily to realize than the pillar thick 10% of end through making the pillar that limits cancellated central zone.
As shown in Figure 7, the instrument of assisting valve member is sewn to the appropriate location on the support also is provided.Instrument (40) comprises each since a pair of narrow microscler clamp (42) that handle (44) extends, and handle at one end (46) is located to be fixed together.Clamp (42) and handle (44) are processed by rustless steel, and are configured as in the end (46) and locate biasing ground separately.Free end (50) beginning of slot corresponding (48) along each clamp (42) from clamp (42) medially extended, and in slit (48), respectively has the arc notch of array of spaced (52).Notch (52) is configured as can ccontaining suture needle.
In use, the connection sidepiece (16) of lobe leaf (12) is through keeping propping up the sidepiece of support between clamp (42), subsequently they sewed up in place, wherein notch (52) as template to guarantee concordance.
This instrument manufactures suitable simple, and the convenient widely manufacturing of support, because this instrument allows valve member to be held in place and to allow when so keeping, fixed through suture.Should be understood that, have other embodiment fall into the instrument in the scope of the present invention, particularly about the embodiment of the shape of the slit in clamp and the clamp.
Claims (13)
1. a cardiac valve (1); Said cardiac valve (1) comprises the valve member that is fixed in the support (2); Said valve member comprises a plurality of lobe leaves (12) that are fixed together, said valvular being characterised in that, and said lobe leaf is that the biomaterial of 0.3mm is processed by maximum ga(u)ge.
2. cardiac valve according to claim 1, wherein, the maximum ga(u)ge of said biomaterial is 0.25mm.
3. according to described cardiac valve in claim 1 or 2, wherein, each lobe leaf has the sidepiece (18) of bowed shape, and the sidepiece of said bowed shape (18) is used to be attached to said support.
4. according to each described cardiac valve in the aforementioned claim, wherein, said support has the maximum gauge of about 7.5mm under its state that curls.
5. cardiac valve according to claim 4, wherein, said support has the maximum gauge of about 7.0mm under its state that curls.
6. according to each described cardiac valve in the aforementioned claim, wherein, said biomaterial is the kangaroo tissue of suitably handling.
7. cardiac valve according to claim 6, wherein, said kangaroo tissue is the ADAPT of the Celxcel company limited (BioMD company limited) that utilizes Perth city, Western Australia
TMThe tissue of technical finesse.
8. according to each described cardiac valve in the aforementioned claim, wherein, the sleeve of being processed by porous biocompatible material (6) extends along the length of said support around the outer surface of said support at least in part.
9. cardiac valve according to claim 8, wherein, said telescopic material is selected from porous polyester and expanded ptfe (PTFE).
10. according to Claim 8 or 9 described cardiac valve, wherein, said sleeve extends on the whole length of said support.
11. each described cardiac valve in 10 according to Claim 8, wherein, said sleeve is fixed on the said support through suture (22), and said suture (22) extends along said telescopic each end usually.
12. according to each described cardiac valve in the aforementioned claim, wherein, said Framework construction becomes at first to locate to expand in two ends (8,9).
13. cardiac valve according to claim 12; Wherein, The form of said support is the net that is limited on interconnective pillar, through making the pillar in the central area firmer than the pillar in the end regions, makes the material of said support in said central area, be reinforced.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA200809338 | 2009-02-28 | ||
ZA2008/09338 | 2009-02-28 | ||
PCT/IB2010/000398 WO2010097694A1 (en) | 2009-02-28 | 2010-02-26 | A heart valve |
Publications (1)
Publication Number | Publication Date |
---|---|
CN102395330A true CN102395330A (en) | 2012-03-28 |
Family
ID=42665051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800097454A Pending CN102395330A (en) | 2009-02-28 | 2010-02-26 | A heart valve |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN102395330A (en) |
AU (1) | AU2010217291B2 (en) |
WO (1) | WO2010097694A1 (en) |
ZA (1) | ZA201106839B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104799975A (en) * | 2015-04-20 | 2015-07-29 | 杭州嘉和众邦生物科技有限公司 | Artificial bioprosthetic heart valve and production method thereof |
CN105473105A (en) * | 2013-03-15 | 2016-04-06 | 心脏结构导航公司 | Catheter-guided replacement valves apparatus and methods |
CN110731836A (en) * | 2018-07-20 | 2020-01-31 | 先健科技(深圳)有限公司 | Heart valve |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0143246B1 (en) * | 1983-09-23 | 1991-11-27 | Peter Kennedy Pty. Ltd. | Heart valve prosthesis |
US5489297A (en) * | 1992-01-27 | 1996-02-06 | Duran; Carlos M. G. | Bioprosthetic heart valve with absorbable stent |
US5562729A (en) * | 1994-11-01 | 1996-10-08 | Biocontrol Technology, Inc. | Heart valve |
US20030212454A1 (en) * | 2002-05-08 | 2003-11-13 | Scott Michael J. | Compressed tissue for heart valve leaflets |
US20040148018A1 (en) * | 1999-01-26 | 2004-07-29 | Carpentier Alain F. | Flexible heart valve and associated connecting band |
US20070239369A1 (en) * | 2006-03-31 | 2007-10-11 | Tokyo Electron, Ltd. | Creating a virtual profile library |
US20090111241A1 (en) * | 2003-06-24 | 2009-04-30 | Sang-Yun Lee | Wafer bonding method |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070239269A1 (en) * | 2006-04-07 | 2007-10-11 | Medtronic Vascular, Inc. | Stented Valve Having Dull Struts |
EP2247264A4 (en) * | 2008-02-29 | 2011-08-31 | Florida Int Univ Board Trustees | Catheter deliverable artificial multi-leaflet heart valve prosthesis and intravascular delivery system for a catheter deliverable heart valve prosthesis |
-
2010
- 2010-02-26 CN CN2010800097454A patent/CN102395330A/en active Pending
- 2010-02-26 AU AU2010217291A patent/AU2010217291B2/en active Active
- 2010-02-26 WO PCT/IB2010/000398 patent/WO2010097694A1/en active Application Filing
-
2011
- 2011-09-20 ZA ZA2011/06839A patent/ZA201106839B/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0143246B1 (en) * | 1983-09-23 | 1991-11-27 | Peter Kennedy Pty. Ltd. | Heart valve prosthesis |
US5489297A (en) * | 1992-01-27 | 1996-02-06 | Duran; Carlos M. G. | Bioprosthetic heart valve with absorbable stent |
US5562729A (en) * | 1994-11-01 | 1996-10-08 | Biocontrol Technology, Inc. | Heart valve |
US20040148018A1 (en) * | 1999-01-26 | 2004-07-29 | Carpentier Alain F. | Flexible heart valve and associated connecting band |
US20030212454A1 (en) * | 2002-05-08 | 2003-11-13 | Scott Michael J. | Compressed tissue for heart valve leaflets |
US20090111241A1 (en) * | 2003-06-24 | 2009-04-30 | Sang-Yun Lee | Wafer bonding method |
US20070239369A1 (en) * | 2006-03-31 | 2007-10-11 | Tokyo Electron, Ltd. | Creating a virtual profile library |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105473105A (en) * | 2013-03-15 | 2016-04-06 | 心脏结构导航公司 | Catheter-guided replacement valves apparatus and methods |
CN104799975A (en) * | 2015-04-20 | 2015-07-29 | 杭州嘉和众邦生物科技有限公司 | Artificial bioprosthetic heart valve and production method thereof |
CN104799975B (en) * | 2015-04-20 | 2017-05-24 | 杭州嘉和众邦生物科技有限公司 | Artificial bioprosthetic heart valve and production method thereof |
CN110731836A (en) * | 2018-07-20 | 2020-01-31 | 先健科技(深圳)有限公司 | Heart valve |
CN110731836B (en) * | 2018-07-20 | 2021-10-12 | 先健科技(深圳)有限公司 | Heart valve |
Also Published As
Publication number | Publication date |
---|---|
ZA201106839B (en) | 2012-07-25 |
AU2010217291B2 (en) | 2015-03-26 |
AU2010217291A1 (en) | 2011-10-20 |
WO2010097694A1 (en) | 2010-09-02 |
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