CN102626345A - Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant - Google Patents

Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant Download PDF

Info

Publication number
CN102626345A
CN102626345A CN2012101055924A CN201210105592A CN102626345A CN 102626345 A CN102626345 A CN 102626345A CN 2012101055924 A CN2012101055924 A CN 2012101055924A CN 201210105592 A CN201210105592 A CN 201210105592A CN 102626345 A CN102626345 A CN 102626345A
Authority
CN
China
Prior art keywords
titanium
artificial tooth
sintering
temperature
spiral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012101055924A
Other languages
Chinese (zh)
Inventor
王玉元
王粤凡
黄舒婉
黄日胜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanning Yueyang Science & Technology Co., Ltd.
Original Assignee
王玉元
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 王玉元 filed Critical 王玉元
Priority to CN2012101055924A priority Critical patent/CN102626345A/en
Publication of CN102626345A publication Critical patent/CN102626345A/en
Pending legal-status Critical Current

Links

Abstract

The invention discloses a method for fusing a bioactive material on the surface of an artificial tooth pure titanium spiral-shafted implant. The method comprises the following steps of: coating a layer of titanium slurry of 0.02-0.08 millimeter on the surface of the artificial tooth pure titanium spiral-shafted implant, sintering in vacuum after the titanium slurry becomes dry, and controlling the temperature at 1,000-1,500 DEG C; adding 20-30 percent of water into nano-scale artificial bone meal for bending into paste, filling titanium holes with a vacuum grouting method, and sintering at a low temperature; coating a layer of bone to form proteins, and performing freeze drying and refrigeration for later use; or before clinical use, wrapping with blood platelet-rich blood plasma. The method has the advantages of easiness, convenience, avoidance of the influence of high temperature on a material, reduction in hydroxyl denaturation and crystallinity degree, material crispness, cracking and stripping of a substrate, no need of special equipment, low cost, easiness for batch production, and the like.

Description

The method of the molten attaching organism active material in artificial tooth pure titanium spiral-shafted implant surface
Technical field
The present invention relates to a kind of method for preparing of Titanium manual tooth planting body, the method for the molten attaching organism active material in especially a kind of artificial tooth pure titanium spiral-shafted implant surface.
Background technology
Plant the tooth technology and had more than 20 year with using in Research in China; Domestic implantation body remains naked titanium and adds sandblast; China was subsidized by the Chinese Natural Science Foundation before 24 years; Former Sichuan University, former West China medical college and photoelectricity institute are studied active artificial bone hydroxyapatite (HA) and biological glass ceramic (BGC) success.And be tested and appraised in JIUYUE, 1986, reach advanced world standards, obtained Chinese Academy of Sciences's first prize, combine not firmly because of substrate at last by West China medical college veto by one vote, the inanimate object active material uses on Chinese Dental Implant more even to this day.
The surface active material processing method has in the world: (1) coating sintering method; (2) plasma spraying method; (3) laser melts and attaches method; (4) ion beam assisted depositing method; (5) electrophoretic deposition; (6) anodizing etc.All be because the fusing point of titanium more than 1550 °, wants to cement admittedly, necessary high temperature, high temperature causes chemical reaction, the hydroxyl degeneration, degree of crystallinity reduces, and perhaps material fragility increases, and the substrate be full of cracks has influenced practical function, can not get clinical sure.
Summary of the invention
The objective of the invention is to work out a kind of firm with implantation body's titanium and titanium sand sintering; Let bone conduction material activity artificial bone not receive temperatures involved again, be anchored in the titanium valve hole, add bone induction material simultaneously; Promote osteocyte and implantation body to adhere in early days, breed, thereby form synosteosis quickly.
Technical scheme of the present invention:
At surfaces coated one deck 0.02-0.08mm of titanium spiral-shafted implant titanium slurry, wait to do solid final vacuum sintering, forbid to burn molten point, make its sintering firm, there is hole to interconnect between the titanium sand.And after annealing does not become fragile material.
The water mill that adds the material of bone conduction material artificial bone hydroxyapatite and so on 20-30% becomes screened stock; Adopt vacuum grouting process to fill titanium sand hole crack, low-temperature sintering becomes solid again, perhaps the electrophoretic deposition artificial bone; It is solid in hole to let artificial bone tie, and is anchored between titanium sand to be interconnected.
Pouring into the also surface of the implantation body of low-temperature sintering artificial bone, repaste covers one deck has the bone of bone-inducing factor to induce the dawn white, and lyophilizing cold preservation is subsequent use, or before clinical use, attaches use with being rich in platelet blood plasma bag, thereby form synosteosis faster.Platelet is the natural origin of somatomedin, obtains easily.
Implantation body of the present invention titanium and titanium sand sintering are firm, and vacuum pours into the inorganic artificial bone of biologically active in this firm substrate, are anchored in the titanium sand hole crack through low-temperature sintering; Repaste attaches one deck, and to have bone formation dawn of bone inducement son white; Promote that osteocyte adheres in early days, breeds, thereby form synosteosis quickly, make interface synosteosis rate higher; Tiltedly synosteosis and gingiva close attachment are arranged the shoulder place at the flat alveolar ridge of implant neck; Can strengthen the resistance of periodontal, reduce the absorption of alveolar bone and gingiva, become aesthstic implantation body.
The inventive method is easy, has avoided the influence of high temperature to material, the hydroxyl degeneration, and degree of crystallinity reduces, and material becomes fragile and the substrate be full of cracks is peeled off etc., and this law does not need special installation, and cost is low, easy production in batch.
 
The specific embodiment
Embodiment 1
Mix (ratio of titanium valve and dextrin 1 to 1) with 30 μ m-40 μ m titanium valves and dextrin, evenly be sprayed in the titanium helical form implantation body, THICKNESS CONTROL is between 0.02-0.05mm; Move in the Zirconium oxide sintering stove that dentistry is used always negative 2 atmospheric pressure, vacuum-sintering after waiting to do admittedly; Temperature is controlled between 1000-1200 ℃, annealing in process thereafter, the multiple original toughness of titanium ash that lets the sintering hardening become fragile; Detect and whether bond firmly; Whether hole conforms to requirement (hole 2-15 μ m, the hole of 1-3 layer phase intercommunication), otherwise reburns once by last method repaste.
Artificial bone is a trade name, and wherein hydroxyapatite is the most frequently used.Buy the nano-grade hydroxy apatite powder and get final product, add 20% water furnishing slurry; Oneself mill requires granularity at 1-3 μ m, and priming by vacuum is in the firm sand hole of the titanium layer by layer crack of bonding.Artificial bone is selected hydroxyapatite (HA) for use, and market is on sale.After implant surface sintering titanium valve, put into the hydroxyapatite mortar, air is arranged in the pore between the titanium valve; Formed bubble, the artificial bone mortar is impenetrable, must be together with mortar and implantation body's evacuation; Take bubble away, negative two atmospheric pressure lean on atmospheric pressure to compress into mortar.In the low-temperature sintering anchoring, temperature is controlled at 200 ℃ to 250 ℃ again.Avoid artificial bone chemically reactive at high temperature, the hydroxyl degeneration, degree of crystallinity worker reduces or substrate separates or the like.
Artificial bone material implant surface repaste covers one deck bone formation dawn white (BMP) irritating well, and lyophilizing cold preservation is subsequent use.
Can promote that like this osteocyte adheres in early days, breeds; Quickly and synosteosis; Make bone interface combination rate higher, synosteosis also arranged at the oblique shoulder place of the flat alveolar ridge of the cervical region of implantation body, gingiva to bone just adhere to closely can prevention of bacterial erosion; Strengthen periodontal resistance and the absorption that reduces alveolar bone and gingiva, become aesthstic implantation body.
Embodiment 2
Mix (ratio of titanium valve and dextrin 1 to 1) with 30 μ m-40 μ m titanium valves and dextrin, evenly be sprayed in the titanium helical form implantation body, THICKNESS CONTROL is between 0.05-0.08mm; Move in the Zirconium oxide sintering stove that dentistry is used always negative 2 atmospheric pressure, vacuum-sintering after waiting to do admittedly; Temperature is controlled between 1400-1500 ℃, annealing in process thereafter, the multiple original toughness of titanium ash that lets the sintering hardening become fragile; Detect and whether bond firmly; Whether hole conforms to requirement (hole 2-15 μ m, the hole of 1-3 layer phase intercommunication), otherwise reburns once by last method repaste.
Artificial bone is selected biological glass ceramic (BGC) for use, and market is on sale, adds 30% water furnishing slurry.After implant surface sintering titanium valve, put into mortar, air is arranged in the pore between the titanium valve; Formed bubble, the artificial bone mortar is impenetrable, must be together with mortar and implantation body's evacuation; Take bubble away, negative two atmospheric pressure lean on atmospheric pressure to compress into mortar.In the low-temperature sintering anchoring, temperature is controlled at 400 ℃ to 500 ℃, or the electrophoretic deposition artificial bone again.Avoid artificial bone chemically reactive at high temperature, the hydroxyl degeneration, degree of crystallinity worker reduces or substrate separates or the like.
Artificial bone material implant surface repaste covers one deck bone formation dawn white (BMP) irritating well, is rich in platelet blood plasma with the centrifuge preparation before using clinically and uses at once.(PRP) platelet is the natural origin of somatomedin, produces easily.
Embodiment 3
Mix (ratio of titanium valve and dextrin 1 to 1) with 30 μ m-40 μ m titanium valves and dextrin, evenly be sprayed in the titanium helical form implantation body, THICKNESS CONTROL is between 0.02-0.08mm; Move in the Zirconium oxide sintering stove that dentistry is used always negative 2 atmospheric pressure, vacuum-sintering after waiting to do admittedly; Temperature is controlled between 1200-1300 ℃, annealing in process thereafter, the multiple original toughness of titanium ash that lets the sintering hardening become fragile; Detect and whether bond firmly; Whether hole conforms to requirement (hole 2-15 μ m, the hole of 1-3 layer phase intercommunication), otherwise reburns once by last method repaste.
Artificial bone selects for use calcium triphosphate (TCP) market on sale, adds 25% water furnishing slurry.After implant surface sintering titanium valve, put into mortar, air is arranged in the pore between the titanium valve; Formed bubble, the artificial bone mortar is impenetrable, must be together with mortar and implantation body's evacuation; Take bubble away, negative two atmospheric pressure lean on atmospheric pressure to compress into mortar.In the low-temperature sintering anchoring, temperature is controlled at 300 ℃ to 350 ℃, or the electrophoretic deposition artificial bone again.
Artificial bone material implant surface repaste covers one deck bone formation dawn white (BMP) irritating well, and lyophilizing cold preservation is subsequent use.

Claims (3)

1. the method for the molten attaching organism active material in an artificial tooth pure titanium spiral-shafted implant surface, it is characterized in that: at surfaces coated one deck 0.02-0.08mm of artificial tooth's titanium spiral-shafted implant titanium slurry, wait to do solid final vacuum sintering, temperature is controlled between 1000-1500 ℃; The water that adds 20-30% to the artificial bone meal of nanoscale is again transferred and is mixed slurry, adopts vacuum grouting process to fill the titanium hole, again low-temperature sintering; And then coating one deck bone formation dawn is white, and lyophilizing cold preservation is subsequent use; Or before clinical use, attaches use with being rich in platelet blood plasma bag.
2. the molten method of attaching active material in the pure titanium spiral-shafted implant of artificial tooth according to claim 1 surface is characterized in that the inorganic artificial bone of said biological activity is meant: any one of hydroxyapatite, biological glass ceramic, calcium triphosphate, biphasic calcium phosphate or coral hydroxyapatite.
3. the method for the molten attached active material in artificial tooth according to claim 1 pure titanium spiral-shafted implant surface, it is characterized in that: said low-temperature sintering is that temperature is controlled at 200 ℃ to 500 ℃.
CN2012101055924A 2012-04-12 2012-04-12 Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant Pending CN102626345A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012101055924A CN102626345A (en) 2012-04-12 2012-04-12 Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2012101055924A CN102626345A (en) 2012-04-12 2012-04-12 Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant

Publications (1)

Publication Number Publication Date
CN102626345A true CN102626345A (en) 2012-08-08

Family

ID=46584856

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012101055924A Pending CN102626345A (en) 2012-04-12 2012-04-12 Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant

Country Status (1)

Country Link
CN (1) CN102626345A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015158098A1 (en) * 2014-04-18 2015-10-22 南宁越洋科技有限公司 Dental implant made of zirconia ceramic-fused-bioactive glass ceramic artificial bone dust
CN108785742A (en) * 2018-09-04 2018-11-13 南宁越洋科技有限公司 A kind of preparation method of the artificial tooth with good skeletonization efficiency

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071434A (en) * 1990-04-20 1991-12-10 Ngk Spark Plug Co., Ltd. Biologically active surface ceramic and process for producing the same
JPH05154191A (en) * 1991-12-03 1993-06-22 Tdk Corp Bioactive implant and production thereof
CN2179115Y (en) * 1993-12-18 1994-10-12 王玉元 Dual mini-hole artificial tooth planting body
US6248344B1 (en) * 1997-04-21 2001-06-19 Heimo Ylänen Composite and its use
CN101304771A (en) * 2005-11-02 2008-11-12 施乐辉骨科用品股份公司 Open-cell biocompatible coating for an implant, method for the production thereof, and use thereof
CN101518467A (en) * 2009-03-06 2009-09-02 中南大学 Medicinal porous titanium implant and method for preparing same
CN102145192A (en) * 2010-02-05 2011-08-10 财团法人金属工业研究发展中心 Metal implant and surface treatment method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071434A (en) * 1990-04-20 1991-12-10 Ngk Spark Plug Co., Ltd. Biologically active surface ceramic and process for producing the same
JPH05154191A (en) * 1991-12-03 1993-06-22 Tdk Corp Bioactive implant and production thereof
CN2179115Y (en) * 1993-12-18 1994-10-12 王玉元 Dual mini-hole artificial tooth planting body
US6248344B1 (en) * 1997-04-21 2001-06-19 Heimo Ylänen Composite and its use
CN101304771A (en) * 2005-11-02 2008-11-12 施乐辉骨科用品股份公司 Open-cell biocompatible coating for an implant, method for the production thereof, and use thereof
CN101518467A (en) * 2009-03-06 2009-09-02 中南大学 Medicinal porous titanium implant and method for preparing same
CN102145192A (en) * 2010-02-05 2011-08-10 财团法人金属工业研究发展中心 Metal implant and surface treatment method thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
付俊: "钛种植体表面HA涂层技术的研究进展", 《国外医学.口腔医学分册》 *
储成林等: "致密羟基磷灰石(HA)生物陶瓷烧结行为和力学性能", 《功能材料》 *
张学鹏: "多孔NiTi合金种植材料生物相容性研究", 《中国优秀博硕士学位论文全文数据库(硕士) 医药卫生科技辑》 *
许国栋等: "《钛材生产加工与应用》", 30 November 2011 *
谢永林等: "钛及钛合金种植体表面涂层处理的研究进展", 《川北医学院学报》 *
陈鹭滨: "粉末烧结多孔钛的组织与性能研究", 《中国优秀硕士学位论文全文数据库 工程科技I辑》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015158098A1 (en) * 2014-04-18 2015-10-22 南宁越洋科技有限公司 Dental implant made of zirconia ceramic-fused-bioactive glass ceramic artificial bone dust
CN108785742A (en) * 2018-09-04 2018-11-13 南宁越洋科技有限公司 A kind of preparation method of the artificial tooth with good skeletonization efficiency
CN108785742B (en) * 2018-09-04 2021-06-22 南宁越洋科技有限公司 Preparation method of artificial tooth with good osteogenesis effect

Similar Documents

Publication Publication Date Title
US5125971A (en) Living hard tissue replacement, its preparation
US10322001B2 (en) Implant having a multilayered coating and a process for preparing thereof
CN102978677B (en) Preparation method and applications of wear resistance and antibacterial bioactivity ceramic membrane for surface of titanium or titanium alloy
KR100809574B1 (en) Bio-affinity implant
Hahn et al. Preparation and in vitro characterization of aerosol-deposited hydroxyapatite coatings with different surface roughnesses
WO1992014422A1 (en) Composite bio-implant and production method therefor
EP2189132A3 (en) Surface treated polycrystalline ceramic orthodontic bracket and method of making same
CN103539485A (en) Method for carrying out surface modification on ceramic material through liquid permeation
CN106725945B (en) A kind of preparation method of the GF and PEEK composite material artificial tooth of novel B GC coating
JP2005519194A (en) Method for covering a device with a ceramic layer, ceramic surface layer and coated device
Ke et al. Enhancing the bioactivity of yttria-stabilized tetragonal zirconia ceramics via grain-boundary activation
Shtansky et al. Recent progress in the field of multicomponent bioactive nanostructured films
CN104803673B (en) A kind of hydroxyapatite/Ti acid sodium composite boilogical ceramic and preparation method thereof
CN102821793A (en) Process for preparing an osteointegrative surface on a ceramic body
CN102626345A (en) Method for fusing bioactive material on surface of artificial tooth pure titanium spiral-shafted implant
CN101229100A (en) Dentistry zirconia and leucite compound porcelain powder and preparing method thereof
Li et al. Fabrication and characterization of bioactive zirconia-based nanocrystalline glass-ceramics for dental abutment
Ko et al. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces
CN101653384B (en) Dental implant of surface nano-structure and manufacturing method thereof
CN1830894A (en) Bioactivity, porous nanometer titanium oxide ceramic used for sclerous tissues restoration and its prepn. method
JP3401552B2 (en) Plastic ceramics and method for producing the same
CN101219894A (en) Process for manufacturing zirconium oxide/lanthanum phosphoric acid full porcelain oral cavity body material which can be cut
CN111035814A (en) Preparation method of titanium alloy hard tissue implant material
Zhang et al. Fabrication and in vitro biological evaluation of zirconia ceramics with 58S bioglass via vacuum pressure infiltration for dental implant
CN107604415A (en) A kind of method for preparing the biological coating containing strontium on titanium-based metal surface

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: NANNING YUEYANG SCIENCE AND TECHNOLOGY CO., LTD.

Free format text: FORMER OWNER: WANG YUYUAN

Effective date: 20121018

C41 Transfer of patent application or patent right or utility model
COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: 530022 NANNING, GUANGXI ZHUANG AUTONOMOUS REGION TO: 530007 NANNING, GUANGXI ZHUANG AUTONOMOUS REGION

TA01 Transfer of patent application right

Effective date of registration: 20121018

Address after: 530007 the Guangxi Zhuang Autonomous Region XiXiangTang Nanning Branch Park Avenue Branch Park Building 5 Room 502

Applicant after: Nanning Yueyang Science & Technology Co., Ltd.

Address before: The mayor of Nanning Lake Road 530022 the Guangxi Zhuang Autonomous Region Nanhu International Plaza, two floor Meijie dental clinic 2A06

Applicant before: Wang Yuyuan

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120808