CN102770173A - Automatic injection device with delay mechanism including dual functioning biasing member - Google Patents

Abstract

An automatic injection apparatus including a delay mechanism for properly delivering medication prior to the needled syringe of the apparatus being retracted. In one form, the delay mechanism includes a shuttle for the syringe, a follower, a locking member, a damping compound between the follower and a supporting surface to dampen rotation of the follower relative to the shuttle, and a dual functioning biasing member acting between the shuttle and the follower. When the locking member moves to a release position during an injection, the dual functioning biasing member first provides a torsional force to force the follower to rotate relative to the shuttle from a latching position to an unlatching position, and then the dual functioning biasing member provides an axial force to force the shuttle axially relative to the follower to move the shuttle for retracting the syringe needle into the housing of the apparatus after injection.

Description

The automated injection device that has the delay device that comprises the dual-use function biasing member

Technical field

The present invention is about medication injection device, and especially about a kind of automated injection device.

Background technology

The patient who suffers from many various disease must frequent own injection medicament.Propose multiple device and be convenient to these injections.One kind of means is an automated injection device.Such device makes the syringe needle that before triggering, is arranged on the syringe in the device case insert automatically in the user body when being triggered by user, and then injects the medicine of doses automatically through this syringe needle that is inserted into.A kind of automated injection device of known type also makes automatically when administration finishes and covers the cover reach to cover syringe needle.Have structure more desirable for some application rather than having in the automated injection device of another type of covering cover of reach, this device will make syringe needle automatically retract in the housing when administration finishes.The difficulty that design has the automatic infusion appliance of needle retracted characteristic is, should guarantee that desired syringe contents is injected fully, guarantees that again the syringe needle of syringe is withdrawn in the device case after use rightly.

International publication number WO2005/115516 has explained the difficulty of this design in more detail, and has further proposed solution, and this solution is used one type of delay device that comprises the high viscosity fluid damping.Although have effect, these solutions are not have they self defective, during injecting, are used for transmitting power to syringe such as delay device.

International publication number WO2008/112472 discloses a kind of automatic injector that has delay device, and it has the ability of expectation, but it has than the desired bigger diameter of some application possibilities.In addition, the number of parts and feasible assembling of cam and the complicated operationization that have the delay device of the part that slides relative to each other.

Automatic injector is typically provided with locked plug-in unit, and this locked plug-in unit had stoped the triggering of device before user has been prepared such triggering.A kind of known mode that triggers automatic injector is the button that can manually operate; This button is used for making the spring-loaded jaw of depressing element of device to remove breech lock; Such as allowing jaw to pass through the one or more openings in the surface through outwards opening or inwardly pushing such jaw, jaw is latchable on the opening releasedly.Past has used in order to the releasing breech lock that prevents this plunger too fast various means has taken place, but such as owing to strengthened the complexity of device or increased the non-desired size of device, these means are not the defective that does not have them.

Therefore, expectation provide a kind of overcome prior art these with other defective in the automatic injection device of one or more defectives.

Summary of the invention

In a kind of form of the present invention; The invention provides a kind of delay device that is used for automatic injection device; This automatic injection device has housing, has the band needle applicator of plunger; And at least one biased element, biased element is used to make the band needle applicator in housing, to move along first direction, is used for injection so that make the syringe needle of syringe extend beyond housing and make plunger advancement come the contents of pushing syringe to pass syringe needle.Delay device comprises: be used for the round device of syringe, round device comprises first latch component; Driven member, it comprises second latch component, second latch component is used for moving to limit the round device second direction opposite with respect to driven member edge and first direction with the cooperation of first latch component; Lock Part; It can be through moving to off-position from latched position with the plug engages of syringe in housing during injecting; Lock Part prevents driven member with respect to the rotation that comes and goes device when being in latched position, Lock Part allows driven member with respect to the rotation that comes and goes device when being in the off-position; Damping paint (damping compound), it is between driven member and the area supported, is used for respect to coming and going the rotation that device suppresses driven member; And the dual-use function biasing member, it acts on and comes and goes between device and the driven member, and this biasing member both provided and has impelled driven member with respect to the twisting resistance that comes and goes the device rotation, provided again to impel to come and go the axial force of device away from driven member; Thus; When during Lock Part is being injected, moving to the off-position; The dual-use function biasing member at first promotes driven member and rotates to the releasing position latching with respect to round device from position latching; First latch component and second latch component cooperation at the position latching place; Be disengaged at releasing position latching place's second latch component and first latch component, and the dual-use function biasing member promotes to come and go device vertically with respect to driven member then, after injection, make in the needle retracted housing of syringe so that move round device.

An advantage of the present invention is that delay device can be provided for automatic injection; This delay structure allows not to discharge or under the situation of the driving spring of the syringe that is unable to, syringe needle is withdrawn in time from the driving spring of syringe, and delay device do not relate to syringe needle basically and insert during and during injecting, be applied to the operating physical force on the syringe then.

Another advantage of the present invention is that automated injection device can be provided with elongated profile.

Another advantage of the present invention is automated injection device and such as wherein delay device, the parts that use decreased number can be provided and still have reliably carrying out of device operation simultaneously.

Description of drawings

In conjunction with the following description of accompanying drawing with reference to the embodiment of the invention, above-mentioned and other advantage and purpose of the present invention and the mode that obtains them will become more obvious, and will understand the present invention itself better, in the accompanying drawings:

Fig. 1 is the side view that has the automatic injection device of delay device of the present invention;

Fig. 2 is the longitudinal cross-section view of the automatic injection device among Fig. 1;

Fig. 3 a and Fig. 3 b are respectively perspective view and the longitudinal cross-section view that separates the main casing body of the equipment among the Fig. 1 that illustrates with the miscellaneous equipment member;

Fig. 4 a, Fig. 4 b and Fig. 4 c are respectively perspective view, bottom perspective view and the longitudinal cross-section view that separates the housing base plate of the equipment among the Fig. 1 that illustrates with the miscellaneous equipment member;

Fig. 5 a, Fig. 5 b, Fig. 5 c and Fig. 5 d are respectively perspective view, bottom perspective view, top view and the longitudinal cross-section view that separates the housing safety sleeve of the equipment among the Fig. 1 that illustrates with the miscellaneous equipment member;

Fig. 6 a, Fig. 6 b, Fig. 6 c, Fig. 6 d and Fig. 6 e are respectively perspective view, side view, the first longitudinal cross-section view, bottom perspective view and the second longitudinal cross-section view that separates the button that illustrates with the miscellaneous equipment member;

Fig. 7 a, Fig. 7 b, Fig. 7 c and Fig. 7 d are respectively two perspective views, side view and top views that separate the piston element that illustrates with the miscellaneous equipment member;

Fig. 8 a, Fig. 8 b and Fig. 8 c are respectively perspective view, bottom perspective view and the top view that separates the syringe carrier that illustrates with the miscellaneous equipment member;

Fig. 8 d is carrier but the top view before coating molded syringe carrier that is similar among Fig. 8 c;

Fig. 9 a, Fig. 9 b, Fig. 9 c, Fig. 9 d and Fig. 9 e are respectively with the miscellaneous equipment member and separate perspective view, first side view, second side view, longitudinal cross-section view and the bottom perspective view that comes and goes the device part that go up that illustrates;

Figure 10 a, Figure 10 b, Figure 10 c, Figure 10 d and figure l0e are respectively perspective view, first side view, second side view, longitudinal cross-section view and the bottom view that separates the following round device part that illustrates with the miscellaneous equipment member;

Figure 11 a, Figure 11 b, Figure 11 c, Figure 11 d and Figure 11 e are respectively first perspective view, first side view, second perspective view, second side view and the longitudinal cross-section view that separates the driven member that illustrates with the miscellaneous equipment member;

Figure 12 a, Figure 12 b and Figure 12 c be respectively with the miscellaneous equipment member separate illustrate at unstress state or not perspective view, side view and the top view of the dual-use function biasing member in the condition of preload;

Figure 13 a, Figure 13 b, Figure 13 c and Figure 13 d are respectively perspective view, side view, longitudinal cross-section view and the top view that separates the grease collar that illustrates with the miscellaneous equipment member; And

Figure 14 to Figure 19 be automatic injection device among Fig. 1 in the longitudinal cross-section of the subsequent stage of its operation view.

Run through each view, corresponding reference marks is represented corresponding part.Though accompanying drawing is represented embodiments of the invention, needn't draw accompanying drawing in proportion, and some characteristic possibly exaggerated in some drawings or be omitted so that illustrate and explain the present invention better.

The specific embodiment

Referring now to Fig. 1 and 2,, wherein shows the different views of first embodiment of the automatic injection device that has delay device of the present invention respectively.

Be denoted as 20 automatic injection device on the whole and have trigger, trigger causes the band needle applicator of equipment to be driven when being touched by user downwards, makes that injection needle is outstanding to surpass the bottom of apparatus casing and thrust in the user body.Then, equipment continues through the syringe needle medicine contents in the injection injection device automatically, and after this syringe is automatically withdrawn and made injection needle return in the housing.The delay device of equipment helps to operate stage by stage, is suitably given before the withdrawal of band needle applicator to guarantee the medicine contents.

To recognize that equipment 20 aspect principle is similar to disclosed device the international publication number WO2008/112472 various, should open integral body be incorporated among this paper from following description.

Equipment 20 comprises shell body 22, and the working component of equipment operationally is arranged in the shell body 22.Security control button 25 is located at top or the far-end of housing and projection vertically from it, and security control button 25 is the part of the trigger of user operation.When the safety sleeve 26 of housing is configured to respect to 24 one-tenth suitable angular orientation of enclosure body rotatably being adjusted by user, make button 25 be unlocked, and can press the button 25 start this equipment automatic function of injection.As used herein distally and nearside are meant at equipment and are oriented to when being used for using at this position with respect to the axial location of injection site that thus, for example the near-end of housing is meant the shell ends that approaches this injection site most.

Further illustrate like Fig. 3 a and Fig. 3 b, the tubular body 24 of housing 22 extends between near-end 32 and far-end 34, and by forming such as transparent plastic materials such as ABS plastic.Near body distal end, circumferential or annular snap collar 36 is inwardly outstanding from the enclosure body inner surface.The flank that extends longitudinally 38 that is used to guide syringe to come and go device is given prominence to from body internal surface neighbouring card clasp 36.Near the intermediate length part of body 24, a pair of isolated angledly strut rail or flank 40 are formed on the inner surface of body, to be used to support grease collar or damping ring 300.The spline 42 that extends vertically that is formed on the shell inner surface of strut rail 40 tops is used for ring 300 rotatably is fixed in the housing.One group is departed from along circumferential isolated maintenance buckle or flank 44 and strut rail 40 angledly, and the distally that is positioned at strut rail is used for locating vertically driven member 250.

The housing 22 of shown equipment 20 also is included in the base plate 50 that further illustrates among Fig. 4 a, Fig. 4 b and Fig. 4 c, and the upper body 26 as safety sleeve that in Fig. 5 a, Fig. 5 b, Fig. 5 c and Fig. 5 d, further illustrates.Base plate 50 is by processing with housing body 24 identical materials; And comprise the base section 51 of trilobal substantially; Make base section 51 adaptive (fit) in the opening of the complementary shape at near-end 32 places of enclosure body 24 with key (key), base section 51 is securely fixed in opening part such as fetching through supersonic welding during manufacture.Through the tube portion 54 that distad extends from part 51 center port 52 of bottom parts 51 is circularized, the syringe needle of syringe shifts out and gets back to the housing then from housing through center port 52 during use.The inner surface 55 of tube portion 54 includes the circumferential shoulder 56 that helps syringe centering, and inner surface 55 begins to slope inwardly at the pipe far-end when its proximad extends.One group three arc notches 58 form and pass part 51, and are placed on the distal face of bottom parts 51 through buckle 59.

Syringe top cover (overcap) 320 shown in Fig. 2 is by processing such as plastics such as polypropylene SR549M, and comprises the base 322 that has chimb periphery 323.A series of or three arc cams 325 are aimed at notch 58, and comprise towards outer ratchet 326, and ratchet 326 engages with base plate buckle 59 and is used for releasable interconnection.Be suitable for engaging with syringe needle shield assemblies 330 from base 322 axial tubular rings 328, syringe needle shield assemblies 330 keeps syringe needles aseptic, and when housing 22 removes top cover, removes syringe needle shield assemblies 330 from syringe needle.

The sleeve that the upper body 26 of housing is served as reasons and processed such as opaque Lustran ABS 348 plastic materials such as grade.Manually the main part 62 of grasping transits to the part 64 that diameter reduces, and the part 64 that diameter reduces fits in the top part of housing body 24.At the device assembly process, the circumferential recess 66 storage case snap collar 36 in the Outer cylindrical periphery of sleeve part 64 so that allow to rotatablely move, but prevent the axially-movable between upper body 26 and the main body 24.Relative breach 68 is formed in the proximal of sleeve part 64.A breach 68 has held the far-end of housing key 38, so that the scope of restriction locking bushing rotation.The opening 70 that passes sleeve part 64 is formed for coming and going the locking strut rail 71 of device lock-bit.Be formed on the indicator 73 that exceeds on the periphery of body part 62 and together with lock icon and the unlock icon shown in 76 among Fig. 1 the visual notice function be provided, lock icon and the unlock icon are located on housing body 24 adherent labels 75.Through with the adjacency of the key 38 of the sleeve stop part that limits breach 68, allow when sleeve 26 is arranged on the end angular position with being rotated indicator 73 to aim at icon 76.

The inner surface 78 of housing upper body 26 comprises that three of a group of being used for engaging with device button 25 equate into that angular spacing is opened and inwardly outstanding buckle collision block 80.The outstanding flank 82 that extends vertically that is formed on the surface 78 fits in the notch of button.

Button 25 is by firm but have and suitably elasticly process such as Lustran ABS 348 materials such as grade, and in Fig. 6 a, Fig. 6 b, Fig. 6 c, Fig. 6 d and Fig. 6 e, further illustrated.Button 25 comprises the end plate 88 that has skirt section 90, and extend from its periphery proximad in skirt section 90.End plate 88 has distal face, can directly on distal face, apply power by user, so that press push button is come trigger equipment selectively.The breach 92 that in skirt section 90, forms extends and forms notch vertically in its proximal end, and the flank 82 of notch storage case body 26 is so that rotatably be connected to button 25 and body 26 together.One group three equate into the base position that resilient finger 94 (each is provided with ratchet collision block 95 on its radially inner) that angular spacing opens is located at skirt section 90.Each finger 94 is adjacent to three equate in the finger 97 that angular spacing opens one, and inwardly becomes the stop part 98 at angle also to be located in the skirt section 90.The finger 94 that has a collision block 95 and the device on the round device are cooperated with helping button 25 rotatably is positioned at and are come and gone on the device; And the finger 97 that has a stop part 98 and the device on the round device are cooperated button 25 is attached to and are come and gone on the device, and help device operation stage by stage.

The active element 100 of button is from coiling the suspend height of proximal extremity top of finger 94 and 97 of 88 downside, and active element 100 is substantially tubular.Make the inner surface of button member 100 become the inclined-plane to form cam surface 102 in its proximal end.A pair of in the near-end of element 100 along the opposed breach of diameter 104 as the gap notch.

Skirt section 90 forms and has the opening that passes therebetween, and these openings define great number of elastic buckle or latch piece 106, and buckle or latch piece 106 are used for after press push button, making button 25 fixing with respect to the upper body 26 of housing.Show the latch piece 106 that three this kind one-tenth angular spacings are opened.The ratchet 107 that in the periphery in the skirt section 90 of the nearside of each latch piece 106, forms is convenient to make assembly.

As shown in Figure 2, being denoted as 110 medicine filled syringe on the whole is installed in the equipment 20.Syringe 110 is shown the tube 112 that comprises that the material that is fit to such as glass or other is processed; Wherein injection needle 114 is installed in a proximal end; Injection needle 114 is that fluid is communicated with the medicine contents of syringe cylinder, and injection needle 114 is covered by syringe needle shield assemblies 330 at first.The plunger mechanism of syringe forms two parts by the elastomeric seal member or the piston 118 that are denoted as the medicine in 116 piston element and the sealing drum 112 on the whole.Shown tube 112, syringe needle 114, syringe needle shield assemblies 330 and piston 118 be conventional design, but can be still to provide suitable functional the different structure whiles.For example, when equipment is done suitable change, use flexible syringe needle covering but not perhaps rigidity syringe needle covering is possible, such as engaging of top cover and flexible covering is provided through top cover.

Piston element 116 is by light weight but firm and molded the forming of the competent material of elasticity, such as the Delrin 311DP that comes from Dupont Engineering Polymers.Shown in further among Fig. 7 a, Fig. 7 b, Fig. 7 c and Fig. 7 d; Piston element 116 comprises proximal region 120; Proximal region 120 have at one end dish type leg 121 and in the disk-shaped flange 123 at other end place, leg 121 is used for during plunger advancement operationally against packed-piston 118.Comprise recess or the otch 125 that extends vertically in the mesozone 124 of upwardly extending piston element vertically from flange 123, breach or otch 125 have further exposed the upper surface 126 as the flange 123 of syringe carrier strut rail.The upper end of disk-shaped flange 128 in plunger mesozone 124 that has than flange 123 larger diameters forms.On the outer radial periphery of flange 128, formed suspend bar or crotch 130, its direct engaging lock limiting-members during injecting makes the driven member release of equipment delay device.Trip lever 130 with plunger mesozone 124 concern at interval from flange 128 vertically and proximad extend.

The distal region of piston element 116 is included in and is denoted as 134 a pair of elasticity jaw generally, and jaw is suitable for the round device of breech lock ground junction apparatus, till discharging through the device fires mechanism that is used for illustrated embodiment.Each jaw 134 comprises that from the distad outstanding upright supporting leg 136 of the more core of flange 128 aligned vertically space or spacing 137 are wherein arranged between supporting leg 136.At the far-end of its supporting leg 136, each jaw 134 comprises breech lock device with latch surface 138, at the outside end 139 at scope place, the outside of latch surface 138, and ramped surfaces 141.Latch surface 138 extends radially outward and towards nearside from supporting leg 136 substantially.Latch surface 138 forms and has slight ground cuts, so as from supporting leg 136 proximad slight inclination to terminal 139.Ramped surfaces 141 distad and from terminal 139 inwardly becomes angles to extend from terminal 139, is used for release as mentioned below so that be formed on the slope towards outer that jaw inwardly does to use in the cam.At near its circumferential section exterior domain and between wherein radially, each ramped surfaces 141 is interrupted by the locking projections 143 that forms with surface 141, and locking projections 143 is outstanding along the distally towards button 25.Locking projections 143 extends upward the degree identical with ramped surfaces 141, makes locking projections 143 upwards terminal be set at and the upwards terminal identical height place of ramped surfaces 141.The upwards terminal upwards terminal radial outside that is arranged on ramped surfaces 141 of locking projections 143.Radially the doing towards outer surface 146 of end that make progress of locking projections 143 is circular, so that during device assembles, insert via spring 149.

The relation that locking projections 143 and ramped surfaces 141 are opened at interval makes them limit radial space betwixt.The shape and size that radial space is formed on the V-arrangement opening 145 between the inside face of ramped surfaces 141 and locking projections 143 are confirmed as in order to take in the near-end of button member 100.

The boss 147 that extends vertically that on each supporting leg 136, forms is configured to help to make driving helical spring 149 centering shown in Fig. 2.The near-end of the spring 149 through the clamping frame on the flange 128 150 centering is located and acts on against flange 128, and the far-end of spring 149 is against round device effect.

The molded syringe carrier of coating shown in further is denoted as 155 on the whole among Fig. 8 a, Fig. 8 b, Fig. 8 c and Fig. 8 d, and is fitted on the band key flange 111 with the syringe cylinder that rotatably is fixed together 112.Syringe carrier 155 comprises the base that is formed by the rigid materials such as Merlon of filling such as DCL4036 20% carbon; This base comprises the section 157 of C shape substantially, and the supporting member 158 that has radially to the anchor clamps 159 of inner process projects upwards from C shape section 157.Projection 160 forms in the top of anchor clamps 159, and is used for being convenient to coat molding process.Complete the covering moulded parts 162 than Soft Roll and buffering is provided for the glass syringe that keeps through carriage of the supporting leg of covering base section 157 is so that reduce destructive probability.But the overmold that is fit to is processed by the thermoplastic elastomer (TPE) of injection molding.When equipment 20 is assembled fully; Syringe cylinder 112 fits in the central opening 164 tightly; Wherein make syringe flange 111 vertically lock-bit between the downside of overmold 162 and anchor clamps 159, and wherein the downside of the end region of anchor clamps 159 to the upper surface 126 that is used for the plunger flange 123 that direct supporting engages.Outwards moved from housing 22 before equipment uses through the surface syringes 110 that prevented to remain in the carriage 155 that engage with this supportings syringe carrier anchor clamps 159 126.

The delay device of equipment 20 be included in be marked as generally 170 round device, can with round device 170 driven member 250 of breech lock releasedly, and coming and going the dual-use function biasing member 290 that acts between device and the driven member.In an illustrated embodiment, coming and going device 170 is formed by round device 172 in Fig. 9 a, Fig. 9 b, Fig. 9 c, Fig. 9 d and Fig. 9 e and Figure 10 a, Figure 10 b, Figure 10 c, Figure 10 d and Figure 10 e, further illustrating respectively and following round device 174.During making assembly, round device part 172 and 174 is fixedly attached to like or other connected mode that is fit to adaptive with described buckle and comes together to be used as round device.Many structures are convenient to come and go the molded of device and assembling, and are convenient to element of installation and are assembled in the inner hollow portion 175 that comes and goes device.A kind of suitable material that is used for coming and going device part 172 is for such as transparent plastics such as EXL1992T polycarbonate alloys, and a kind of suitable material that is used for coming and going device part 174 is for such as transparent Merlon such as Makrolon2458.

The base section 176 that go up to come and go device 172 comprises that the alignment block or the key 178 of projection, alignment block or key 178 closely fit in the breach 222 in the far-end 223 of the body 220 that is formed at down round device 174.During the assembly of the round device part of making coupling, be located on the opposite side that comes and goes device 172 radially projection and partly along lip 180 snap-lock of circumferentially extending on the strut rail 225 that the window 226 that comes and goes formation in the device 174 through infra is limited.Pair of keys 182 is outstanding from the periphery of last round device 172, each key 182 above each lip 180, key 182 fit in form in the far-end 223 that comes and goes device body 220 than in the small gap 228.Adaptive and alignment block 178 the fitting in breach 222 in of key 182 in breach 228 will come and go device when being connected and rotatably be fixed together.

The base section 176 that comes and goes device 172 of going up of piece 178 tops comprises opening 184, and locking bending section 186 extends outside 184 one-tenth certain angles of opening.Bending section 186 is fixed on retracted position with locking strut rail 71 cooperations of housing after using, will come and go device.On a side of the round device 172 relative, the opening or the notch 188 that extend to the bottom that comes and goes device that hold plunger crotch 130 are provided with opening 184.Flank 189 usefulness that in the inner surface of base section 176, form act on the stop part by syringe flange 111 adjacency, so that distad move at assembly process restriction syringe 110.

Going up the top part that comes and goes device 172 is the tubular cylinder shape body 190 that has the cover 192 that dangles.The center port 194 of passing cover 192 allows the latch portion of plunger jaw 134 to pass through.From the distad outstanding a pair of clamping frame 196 of the top surface of cover 192 around aperture 194 at diametrically opposite, and help during use the active element 100 of button 25 is directed in the aperture 194.Jaw composition surface 195 between the clamping frame 196 comprises the aslope surface of making progress of contiguous aperture 194, and this surface is complementary so that provide more firm betwixt but releasable the connection with the ground cuts of latch surface 138.The ring 198 that the downside 199 from cover 192 in hollow bulb 175 suspends makes the far-end centering of spring 149, and spring 149 is directly against downside 199 effects.Two the relative excision portions 200 of ring in 198 pass through through the locking projection 143 that ramped surfaces is provided allows jaw 134, and help assembling, and ramped surfaces makes the jaw toe-in at assembly process.

The outer radial periphery of cover 192 comprises three inclined-plane sections 202 and three the platform sections 203 that become interlaced arrangement around the circumference that comes and goes device.Limit the Cheng Jiao end of each platform section 203 through groove or slot part 205.Platform section 203 is designed to have during button rotation along the ratchet 95 of the button finger 94 that platform section 203 slides.Slot part 205 and ratchet 95 cooperations; Button is remained on the position in two preferred angle positions or the position of rotation with respect to round device 170 so that help; But when button is moved between these positions, can easily overcome ratchet and connect.Sense of touch indication and audible indication that interaction between slot part 205 and the ratchet 95 also provides button rotation when to reach home.

It is outstanding from the peripheries of the round device body 190 of contiguous three lid inclined-plane sections 202 to be denoted as three backstop flanks of 204 on the whole.Each backstop flank comprises along the sections 206 that circumferentially extends, at the axial sections 208 that extends vertically at an end place of sections 206, and has the sections 210 that extends vertically that suspends at the leading-in end 211 at the one-tenth angle at the other end place of sections 206.Three backstop flanks 214 that extend vertically are set at the nearside place of three platform sections 203.

During making assembly; Through parts are moved together vertically button 25 is installed on the round device 170; Make that slide in the button finger 97 have stop part 98 and buckle fits on the inclined-plane section 202 of lid, come the distally of impedance button to remove through stop part 98 against the lip that dangles of the inclined-plane section 202 of cover 192 at this some place.When installation button 25 like this, flank sections 206 usefulness act on the axial stop part of button stop part 98, thereby so that against and stop the manual depression button of button when not being in released state.Flank sections 208 is worked with stop part 98, rotate along the opposite way round from lock-out state so that further prevent button 25, and stop part flank 214 prevents that button 25 from rotating too far during release.Flank sections 210 and backstop flank 214 call-on button during the depressing of button is advanced downwards, and longer flank sections 210 usefulness shown in Fig. 9 c act on the abutment of stop part 98, so that prevent manually locking again of sleeve 26 during the FLUID TRANSPORTATION.

Down round device 174 is substantially tubulose, has cylindrical body 220, and cylindrical body 220 progressively is contracted to the cylindrical proximal region 230 that diameter reduces via annular radially aligned flange 221 basically, and proximal region 230 fits in the driven member 250.Flange 211 interrupts through axial ribs regions 247.Flange 221 is as supporting member, and supporting member directly engages syringe carrier 155, to be used for upwards engaging effectively and carrying syringe is regained syringe after injection syringe needle.The bar 238 that distad extends from far-end 223 after injection through fitting in the breach 68 rotatably locking housing sleeve 26.In its proximal end, come and go device 174 and comprise annular lip 233, annular lip 233 radially extends internally, so that limit the opening that syringe cylinder 112 extends through.The annular notch that centers on the end setting of lip 233 outer proximal regions 230 has formed shoulder 231, and shoulder 231 makes and acts on hereinafter described biasing member 290 location and the centering that comes and goes on the device.The groove 232 storage case keys 38 that extend vertically in the following round device body 220 are so that the whole axial stroke of edge round device is wherein rotatably fixed round device 170 and housing 22.

Round device comprises at least one latch component of the driven member that is used for engaging releasedly delay device.Latch component is shown and is provided as one group of lug 234 and 236, and lug 234 and 236 is spaced apart angledly and radially outwards outstanding from proximal region 230 around proximal region 230 near its near-end.The piece shape that lug 234 and 236 is shown different size is outstanding, and outstanding the hook as breech lock engages driven member.

The directed vertically breach of radially outwards opening 240 forms and passes in lug 234 and the entering shoulder 231.Breach 240 is sized to and is configured to take in going up of biasing member and gives prominence to 294.Shown in Figure 10 e, breach 240 is included in the circumferential protuberance at its inside degree of depth place, and circumferentially protuberance causes lug 234 to provide depression 235 to be used for radially keeping going up of biasing member outstanding.

The proximal end of the following round device body 220 on its periphery becomes the bolt latching surface 242 at angle to be formed on wherein.Latch surface 242 is arranged on nearside and the angled ground adjacent openings 244 that is formed at the opening 244 in the ribs regions 247 of upper process.Opening 244 is arranged to be in line with the passage 246 that extends vertically, and passage 246 is formed on down in the inner surface of round device body 220 along its whole height.Limit the edge tilt of the ribs regions 247 of opening 244, crotch 130 is directed in the opening so that help.Passage 246 hold plunger crotch 130 in case loosely rotatably keyed jointing come and go device 170 and piston element 116; Allow piston element 116 with respect to the axially-movable that comes and goes device simultaneously, make that the proximal extremity of crotch 130 can be via the described locking mechanism of opening 244 outstanding release hereinafters.

Further show delay device driven member 250 among Figure 11 a, Figure 11 b, Figure 11 c, Figure 11 d and Figure 11 e.Driven member 250 is formed by the inflexible but competent material of elasticity, so that the Lock Part characteristic is provided integratedly.A kind of suitable material of the driven member 250 shown in being used for is Delrin 311DP.Driven member 250 comprises top part 252, and top part 252 is adaptive with one heart around coming and going device proximal region 230.Two parts form in driven member part 252 along the strut rail 254 and 256 that circumferentially extends, and as the latch component that engages with round device latch tab 234 and 236.Strut rail 254 forms via driven member part 252 through window 258, and becomes the end at angle to lead to the passage 260 that extends vertically that in the inner surface of driven member part 252, forms at one.Strut rail 256 partly leads to window 261, and becomes the place, end at angle to lead to the opening 262 in the driven member part 252 at one.Passage 260 allows lug 234 and 236 therein to move axially with opening 262, to be used to making assembly and to be used for discharging round device with respect to driven member at equipment between the operating period.Opening 262 is tapered towards notch shape part 266 at 264 places, and notch shape part 266 is suitable for closely taking in radially outstanding 296 of biasing member.

Near the base of driven member part 252, radially outwards outstanding from secondary part 252 around the flange 268 of most of circumferential extension.Flange 268 comes buckle via housing buckle 44 during device assembles.The inner surface of driven member part 252 comprises inwardly outstanding ring 270, and ring 270 is provided with three in the above and equates isolated angledly flank 272.Ring 270 is limited with opening, and syringe cylinder extends via opening and to biasing member base is provided, and makes biasing member centering through flank 272.

The sleeve shaped bottom part 274 of driven member 250 suspends and has less diameter from driven member part 252.Four notches 276 in the proximal of part 274 define four damping fins 278 of driven member.

Form with respect to the Lock Part that is used for driven member 250 and the driven member 250 that come and go device 170 rotations in order to limit it.In alternative, can use the Lock Part of constructing differently, it comprises independent part or forms with round device.Lock Part is denoted as 280 on the whole, and forms bend arm 282, and wherein upwardly extending latch piece 284 is at its place, end.Bend arm 282 extends along circumferential direction substantially from the top part 252 of driven member.Bend arm 282 occupies the annular space similar with driven member part 252; And because arm 282 is designed to cause latch piece 284 to move vertically with respect to round device in order to bending vertically; So that the release driven member is used for rotation, so the axial space 286 between the zone of the driven member of arm 282 and window 261 tops part is configured in order to adapt to the bending of arm.For example, if make the latch piece release, just do not need such space through moving radially of latch piece.

By biasing member 290 twisting resistance and axial force are provided during use and cause the dual-use function of biasing member 290, two kinds of power all directly act between driven member 250 and the round device 170.For the structure shown in the equipment 20, biasing member 290 act as twisting resistance torsionspring and compression spring, and can be manufactured to the single member of easy to handle during making assembly.Twisting resistance and axial force are caused by the twisting resistance preload of biasing member 290 and the release of axial pre-load, during the assembly of manufacturing equipment 20, have realized preload.

Biasing member 290 is shown the helical spring that the line 292 of being reeled by scroll forms.Suitable this kind spring is processed by 302 rustless steels that have 0.024 inch linear diameter.Spring 290 is chosen as in order to suitable twisting resistance and axial force to be provided in available space, and selects to depend on the operation (such as required delay) of device and the design (such as the structure of damping paint and driven member and stauffer cup) of cooperating member.Other design of biasing member (such as being configured to) in order to the metal of carrying out dual-use function or the bending section of plastics can by shown in the monometallic helical spring substitute.

The inner opening 295 of spring 290 is freely taken in down round device proximal region 230, and the external diameter of spring 290 freely fits in the top part 252 of driven member.Distal coil 293 against the line 292 that comes and goes device shoulder 231 is terminated at distad outstanding projecting end or terminal 294.Terminal 294 are arranged in the cross section of the cylindrical coil shown in Figure 12 c.Terminal 294 size and dimension is confirmed as in order to fit in to come and go to engage in the device depression 235 and is come and gone device 170.Be terminated at radially end 296 against the proximal coil 297 of the line 292 of driven member ring 270 to outer process.Terminal 296 extend beyond the cross section of cylindrical coil.Terminal 296 size and dimension is confirmed as in order to closely to fit in the opening portion 266, so that engage driven member 250.

During the assembly of manufacturing equipment 20; Its medi-spring 290 is arranged such that terminal 294 and 296 fit in respectively in the depression 235 and opening 266 of isolated driven member 250 and following round device 174; When driven member and round device bottom part being pooled together vertically and rotating so that the interaction breech lock through strut rail 254,256 and lug 234,236; And the interaction through Lock Part 280 and round device surface 242 is so in the locking then, not only vertically but also with twisting resistance mode preloaded spring 290 between driven member 250 and round device bottom part 174.

Further show among Figure 13 a, Figure 13 b, Figure 13 c and Figure 13 d and be denoted as 300 stauffer cup or grease collar on the whole.When driven member 250 rotated with respect to this area supported, cup 300 was provided for the area supported of damper fluid.In alternative, can area supported be provided with other mode, such as forming with enclosure body.Cup 300 is processed by transparent plastic material, such as the ABS TR-558A1 that comes from LG Chemical Ltd.Cup 300 comprises ring body 302, and ring body 302 has columniform substantially periphery and circular center port 303, and the adaptive center port 303 of passing of syringe cylinder is adaptive.Through strut rail 40 cup 300 is bearing in the housing 22 vertically.The keyway 305 that flank 304 limits on the periphery.Show two notches 305; Rotatably make on the spline 42 of cup 300 and housing 22 fixed housings but only need a notch to fit in, and another notch makes that the initial orientation of assembly process is more not crucial and allow assembly process on key 38, to pass through usually.Cup body 302 comprises the wall part 308 of U-shaped substantially, and wall part 308 limits annular hollow bulb or passage 307.The magnification region 309 that leads in the top of hollow bulb 307 is sized to so that hold nozzle well, and damping paint is inserted in the hollow bulb 307 through nozzle.

Damping paint or fluid 315 (such as as Nye fluorocarbon gel 880 from the available silicone grease of Nye Lubricants with the politef thickening) fill annular hollow bulb 307.Driven member fin 278 fits in the hollow bulb 307; Make coating 315 be arranged on the radially inner side and the radial outside of this fin 278; And be arranged between the adjacent fin 278; And as the film between the base of fin downside and driven member wall, when driven member fin 278 is attempted with respect to the rotation of the U-shaped inner surface of wall part 308, caused damping or carryover effects, wherein heavy-gravity damper fluid provides resistance to this rotation during operation.The delay that will provide by delay device that can select according to manufacturer by those skilled in the art and select to have other coating of different nature according to changing; The technical staff can make the others that coating and delay device are disposed in this change, such as the twisting resistance of spring generation and the size and dimension of driven member and grease collar.

To come the structure of further understanding equipment 20 according to the description of its operation.Be configured at first be under the situation in the lock-out state shown in Fig. 1 and Fig. 2 at equipment, can not trigger equipment.If user is applied to the power of depressing on the button 25, then button stop part 98 is vertically against round device flank sections 206.In addition; Wherein gap notch 104 rotatably breaks away from locking projections 143 and aims at because button active element 100 extends in V-arrangement opening 145; So protruding 143 peripheries, and prevent that jaw 134 from moving inward and be enough to be disengaged with round device with rest element 100.

User has overcome engaging of top cover ratchet 326 and buckle 59 and the top cover proximad has been pulled away from housing so that also remove syringe needle shield assemblies 330, manually removes syringe top cover 320 by user then.Through user top cover is reversed with respect to housing and be convenient to remove like this this top cover, cam 325 causes this reversing that the top cover proximad is shifted against the cam effect of plate 51.Syringe carrier anchor clamps 159 and plunger flange surface 126 engage the proximal movement that has limited syringe 110.After removing top cover, such as shown in Figure 14 advancing equipment 20.

In order to allow injection, need to prevent the locking that triggers or insure release., equipment 20 can realize such release before or after being oriented in the injection site.But user grasping locking bushing 26 also manually makes locking bushing 26 with respect to housing body 24 rotations, up to alignment markers 73 with till the unlock icon of icon 76 is aimed at, at the edge housing key 38 of icon 76 place's sleeve breach 68.This rotation of sleeve 26 makes button 25 rotations owing to sleeve 26 is connected with key between the button 25.Except that visible icon, also will indicate release aligning or released state through button finger ratchet 95, button finger ratchet 95 is snapped in the slot part 205 at the place, opposite end of platform section 203, and in Figure 14, the button ratchet is positioned at platform section 203 places at first.At this moment, button stop part 98 has been moved angledly and has broken away from and come and go device flank section 206, and gap notch 104 aims at protruding 143 now rotatably, and equipment 20 is such as shown in Figure 15 arranges and preparation is injected.

In this SBR and at equipment, be positioned under the situation of injection site, will depress or downward power is applied to 25 last times of button when user, when active element 100 engaged with jaw ramped surfaces 141, button 25 began to move in the case follower 26.When button 25 is moved further,,, jaw supporting leg 136 reduced gap 137 so curving inwardly owing to pass through the inside cam of the ramped surfaces of button member 100.Locking projections 143 is adaptive via gap notch 104, inwardly moves in order to avoid prevent this jaw.When jaw 134 has been curved inwardly when being enough to make latch surface 138 to be disengaged with round device surface 195; At this time the plunger jaw can adaptively pass that to come and go device opening 194 adaptive as shown in Figure 16; Thereby driving spring 149 comes actuation plunger element and proximad driven plunger 118 with piston element 116 direct biased downward; This driven motion makes syringe cylinder 112 proximads with respect to 22 motions that come and go device with housing and causes that the end of syringe needle 114 is outstanding to surpass the skin that the housing near-end is used to thrust user, and the medicine contents of pushing syringe is passed this syringe needle and is used for injecting then.In Figure 16; Button 25 is shown at its place, end of depressing, and at this layout place, sleeve flank 82 arrives the end of button notch 92; And push-button latch part 106 buckle below sleeve buckle collision block 80 is adaptive; So that button is remained in its depressed state with respect to housing, and wherein button end plate 88 flushes with the top of sleeve 26, but so that the use of insight indicating equipment.In Figure 16, piston element is shown and comes and goes device and removes breech lock, but is before spring 149 launches downward actuation plunger element significantly.

When piston element 116 when proximad moves during medicine injection; The crotch 130 of piston element as shown in Figure 17 slides in round tank mouth 188; And in passage 246, slide then, up to the proximal extremity of crotch 130 get into opening 244 and against and release Lock Part 280 till.Particularly; Crotch 130 is above latch piece 284; And through using bending section 282 crooked next closed spacings 286 that latch piece 284 is shifted vertically; This transfer vertically makes latch piece 284 and round device latch surface 242 remove breech lock, so that release driven member 250 is used for rotation.Release will be designed to before the nearside of plunger mechanism is advanced end, take place soon usually like this.

When Lock Part 280 releases like this or release, the driven member 250 that promotes like the twisting resistance preload through biasing member 290 rotates at housing 24 internal rotation and around rotatable fixed round device 170.Thickness damping paint 315 dampings between driven member fin 278 and the wall of cup part 308 or supply syringe needle are to the resistance of this driven member rotation; This resistance causes the time lapse before the round device releasing breech lock; During at this moment, can suitably discharge remaining medicine from syringe via syringe needle.Drive driven member 250 around the rotation that comes and goes device 170 through spring 290, up to driven member opening 262 and passage 260 respectively with till round device lug 236 and 234 is aimed at.In 20 residing should the layouts of the equipment shown in Figure 18, lug 234 and 236 does not have strut rail 254 and 256, makes that coming and going device 170 removes breech lock with driven member 250.

When round device 170 is so removed breech lock with driven member 250, as facilitating, come and go device 170 distad translation in housing 24, till the far-end 223 that comes and goes device 174 down contacts the near-end 69 of body 26 through the compressive preload of biasing member 290.When round device 170 is withdrawn, distad will be with needle applicator 110 bands through coming and going device, so that make the proximal extremity of injection needle 114 be retracted to the protective position in the housing 24.Round device remains on this retracted position through the axial force of biasing member 290, and is locked on this retracted position against the buckle of strut rail 71 is adaptive in opening 70 through coming and going device locking bending section 186.Bar 238 through being present in the breach 68 stops user to make the attempt of sleeve 26 with respect to housing 24 rotations.At this moment, equipment is the structure as among Figure 19, and user can be provided with in normal processes or handle this equipment with other mode then.

Equipment 20 is designed to is convenient to its manufacturing assembly.For example, following round device 174, spring 290, driven member 250 and the sub-component that has a damping ring 300 of damping paint 315 can be fitted in the housing sub-component of main body 24 and base plate 50 by buckle.Another assembling process can relate to syringe 100 is placed to the sub-component of last round device 172, driving spring 149, piston element 116, button 25 and sleeve 26 to be aimed at; Make syringe carrier 155 snap assembled on syringe and piston element; This whole sub-component is assembled on the following round device assembly and housing of previous assembling, label is applied on the housing, and then top cover 320 is fixed to housing base plate 50 and engages with the syringe needle shield assemblies 330 of previous assembling.

Though the present invention has been illustrated as and has been described as to have decision design, in the spirit of present disclosure and scope, can revise the present invention.For example, heteroid releasable Lock Part can be used for keeping syringe and driven member fixing rotatably, and irrelevant with the twisting resistance that applies through biasing member.In addition, come and go device and can be used for having in the equipment of other different members with the delay device that is associated, such as alternative toucher locking device, as shown in the toucher locking device can use with heteroid automatic injector travel mechanism.Further; The dual-use function biasing member can be configured in delay device (still having when the release the fluidic delay device with respect to damping due to rotation such as wherein coming and going device and driven member) heteroid member and work; But driven member and round device are not removed breech lock but under the situation about moving together vertically and when driven member changes into housing release breech lock after driven member rotation; And the dual-use function biasing member does not directly act between driven member and the round device in this delay device, but acts between driven member and the housing.Therefore, the application is intended to cover of the present invention any modification, use and the adaptive approach of using its general principle.In addition, the application is intended to cover owing to being included into and is separated from such content of the present disclosure within the as known in the art or common convention relevant with the present invention.

Claims (11)

1. in a kind of automatic injection device, said automatic injection device has: housing; The band needle applicator that has plunger; And at least one biased element; Said biased element is used to make said band needle applicator in said housing, to move along first direction, is used for injection so that the syringe needle of said syringe extends beyond said housing and make said plunger advancement come the pushing syringe contents to pass said syringe needle; Delay device, it comprises:

The round device that is used for said syringe, said round device comprises first latch component;

Driven member, it comprises second latch component, said second latch component is used for cooperating with said first latch component and limits moving of the said round device second direction opposite with said first direction with respect to said driven member edge;

Lock Part; It is through engaging with said syringe plunger during injecting and can in said housing, moving to the off-position from latched position; Said Lock Part prevents the rotation of said driven member with respect to said round device when being in said latched position, said Lock Part allows the rotation of said driven member with respect to said round device when being in said off-position;

Damping paint, it is between said driven member and area supported, so that suppress the rotation of said driven member with respect to said round device;

The dual-use function biasing member; It acts between said round device and the said driven member; Said biasing member both provided and had impelled the twisting resistance of said driven member with respect to said round device rotation, and also provided and impel the axial force of said round device away from said driven member;

When during said Lock Part is being injected, moving to said off-position thus; Said dual-use function biasing member at first promotes said driven member and rotates to the releasing position latching with respect to said round device from position latching; State the cooperation of first latch component and said second latch component in said position latching place; State second latch component and said first latch component breaks away from said releasing position latching place; And said then dual-use function biasing member promotes said round device vertically with respect to said driven member, is used for making syringe needle after injection, to be withdrawn into said housing so that move said round device.

2. delay device according to claim 1, wherein, said dual-use function biasing member comprises helical spring, said helical spring has respectively first end and second end that directly engages with said driven member and said round device.

3. delay device according to claim 2, wherein, said helical spring first end comprises the end that extends radially outward, said end fits in the recess through the formed complementary shape of opening of the body that passes said driven member.

4. delay device according to claim 2, wherein, said helical spring second end comprises the end that extends vertically, said end fits in the recess of the complementary shape that forms in the said round device.

5. delay device according to claim 4, wherein, the said recess that in said round device, forms forms in radially outstanding lug, and said lug comprises said first latch component.

6. delay device according to claim 1, wherein, said area supported comprises the surface of ring, said ring is fixing by revolvably with respect to apparatus casing.

7. delay device according to claim 1; Wherein, Said Lock Part comprises at least one bending section; Said bending section and said driven member form, and through during injecting with the crotch of syringe plunger engage can move to the off-position vertically from latched position with respect to said round device.

8. delay device according to claim 1; Wherein, Said round device comprises supporting member; Said biased element is against said supporting member effect, and said biased element makes said band needle applicator move and make said plunger advancement along said first direction, is used to make the bias voltage of the said round device of said needle retracted not receive the impedance of the said biased element that makes said plunger advancement thus.

9. automatic injection device, it comprises: housing, it comprises main body; The band needle applicator that has plunger, said plunger have a plurality of breech lock jaws, and said plunger jaw extends through at least one opening in the breech locked element in the housing body; Button; It can be rotated with respect to said housing body and said plunger jaw between first angle position and second angle position; Said jaw has and the releasable latch surface that engages of said breech locked element; Said jaw comprises ramped surfaces; Said button comprises at least one active element and at least one biased element, and said active element is used for engaging during with respect to the said button of said main body manual depression said ramped surfaces so that said jaw is made cam, breaks away from and the engaging of said breech locked element thereby move said jaw latch surface; So that said jaw can pass said at least one opening in the said breech locked element; Said biased element is used for when said band needle applicator is moved in said housing, so that make the syringe needle of said syringe extend beyond said housing, and said jaw passes said at least one opening in the said breech locked element; And be used to make said plunger advancement to come the pushing syringe contents to pass said syringe needle and be used for injection, improvement comprises:

Locking projections and jaw ramped surfaces form and project upwards towards said button from said ramped surfaces; The upwards terminal relation of opening at interval of the upwards terminal and said ramped surfaces of wherein said locking projections; So that limit radial spacing therebetween; Wherein when said button is in first angle position; At least one active element of said button extends in said radial spacing, thus through said locking projections with the adjacency of at least one active element of said button impedance said jaw latch surface break away from engage with said breech locked element mobile; And

Said at least one active element of said button also comprises the gap notch; Said notch extends in said radial spacing when said button is in said second angle position; Said thus locking projections fits in the notch of said gap, so that the said jaw latch surface of not impedance breaks away from moving of engaging with said breech locked element.

10. automatic injection device according to claim 9; Wherein, The said upwards terminal said upwards terminal radial outside that is set at said ramped surfaces of said locking projections; And the said upwards terminal of wherein said locking projections radially is made into circle towards outer surface, so that during device assembles, insert via said at least one biased element.

11. automatic injection device according to claim 10; Wherein, Each jaw comprises the supporting leg that has the spring spigot edge, radially the forming towards outer surface and radially extending axially towards outer surperficial upper edge at said supporting leg of said boss and said supporting leg.

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