CN102972309A - Improved Y-arm electronic maze experimental device - Google Patents
Improved Y-arm electronic maze experimental device Download PDFInfo
- Publication number
- CN102972309A CN102972309A CN2012105193247A CN201210519324A CN102972309A CN 102972309 A CN102972309 A CN 102972309A CN 2012105193247 A CN2012105193247 A CN 2012105193247A CN 201210519324 A CN201210519324 A CN 201210519324A CN 102972309 A CN102972309 A CN 102972309A
- Authority
- CN
- China
- Prior art keywords
- support arm
- independent support
- arm
- switch
- independent supporting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Instructional Devices (AREA)
Abstract
The invention relates to a device for testing study memory performance of rats, and belongs to the technical field of experiment tools. A maze experimental device is Y-shaped and comprises three independent supporting arms and a central triangular region which is formed by commonly connecting one end of three slot-shaped independent supporting arms, wherein a cover matched with the shape of the independent supporting arm is formed on each independent supporting arm; dense grids are paved at the slot-shaped bottom and the side wall of each independent supporting arm; the grids at the bottom and the side wall of each independent supporting arm share one power line and are independently controlled by one switch; a triangular grid is arranged at the slot-shaped bottom of the central triangular region, and the grid of the central triangular region is independently controlled by one switch; and an organic glass baffle is arranged at end ports of slot-shaped inside of the other end of each independent supporting arm, a bulb is mounted behind each organic glass baffle, and the bulbs (4a, 4b, 4c) in each independent supporting arm are controlled by one switch.
Description
Technical field
The present invention relates to a kind of for test learning and memory in rats capability device, the true apparatus technical field of testing.
Background technology
In the learning and memory pharmacology, in the research such as anti-ageing medicine a kind of jade and one pharmacological toxicology of new drug nervous system, carry out observation analysis to the variation of laboratory animal study memory or Spatial cognitive Abilities, this need to place animal experimental situation to finish certain behavior usually.At present, the experimental provision for test learning and memory in rats ability has water maze laboratory device, eight arm maze experiment devices, 16 arm maze experiment devices, traditional Y arm electronics maze experiment device etc.
Traditional Y arm maze experiment device is a kind of passing through laboratory animal (rat) hunger, make its body weight be down to about 80% of normal condition, make its study seek a kind of experiment of specific food arm by electro photoluminescence, Y arm maze experiment device is mainly used in test experiments animal working memory mistake and reference memory mistake, be widely used in learning and memory, hippocampus/outer hippocampus research, intelligence is with old and feeble, new drug development/screening/evaluation, pharmacology, toxicology, preventive medicine, Neurobiology, the fields such as the scientific research of a plurality of subjects such as Animal Psychology and behavioural biology and computer-assisted instruction, being approved widely in the world, is that medical colleges and schools carries out the especially first-selected Classic Experiments of learning and Memory research of praxiology research.
But traditional Y arm maze experiment device mainly is to be made of common Y arm lucite device, bottom surface electrical network, camera, computer, illuminating lamp and image capturing system etc., each Y arm end has the food generator, and the strategy that takes food according to analyzing animal namely enters the spatial memory capacity that the parameters such as the number of times, time, correct number of times, errors number, route of each arm can reflect laboratory animal.Existing automatically recording laboratory animal behavioral activity and related data, its price is relatively costly, and in the experimentation, rat can take variety of way to hide electro photoluminescence, causing testing the learning and memory in rats experiment can't carry out, stand with one foot to the knee, climb at Y arm sidewall along the edge walking or directly escape from from common Y arm lucite device such as: rat, these all can cause the error of experimental result or experiment stops.
Summary of the invention
Purpose of the present invention is overcoming the shortcoming of above-mentioned prior art, invents a kind of improved Y arm electronics maze experiment device, and it is simple in structure, easy to operate, from reducing to a great extent experimental period, raise the efficiency, and low price.
The technical scheme that the improved Y arm of the present invention electronics maze experiment device adopts is: the whole Y-shaped shape of maze experiment device, by three independent support arms with by the independent support arm (1a of three groove shapes, 1b, 1c) the central gore territory that jointly is connected to form of an end forms, each independent support arm (1a, 1b, a lid (5a who is complementary with independent support arm configurations is respectively arranged 1c), 5b, 5c), each independent support arm (1a, 1b, groove shape bottom surface 1c) and sidewall are covered with an intensive electrical network (2a separately, 2b, 2c), each independent support arm (1a, 1b, 1c) bottom surface and sidewall electrical network share a power line and separately respectively by a switch (7e, 7f, 7g) separately control; Triangle electrical network (9) also is equipped with in the groove shape bottom surface in middle triangle zone, and the electrical network in middle triangle zone is controlled with a switch (7d) separately; A machine glass partition (3a, 3b, 3c) respectively is equipped with in the inboard termination of the groove shape of each independent support arm (1a, 1b, 1c) the other end, a bulb (4a, 4b, 4c) is equipped with in every machine glass partition (3a, 3b, 3c) back, and each controls (7a, 7b, 7c) with a switch bulb (4a, 4b, 4c) in each independent support arm.
Have fence on each lid (5a, 5b, 5c).
The independent support arm of three groove shapes (1a, 1b, 1c) trisection radiant type, three mutual angles of independent support arm are 120 °.
Operation principle is: all spread intensive electrical network on the bottom surface of each independent support arm of experimental provision of the present invention and sidewall, electrical network on each independent support arm connects with same wire, and with the control of same switch, rat stands with one foot to the knee and climbs problem on experimental provision in can avoiding to a great extent testing like this, again the electrical network in middle triangle zone is controlled with a switch, the bulb of each independent support arm is controlled with a switch, seven switches altogether, switch is arranged on the about 2 meters distant places of independent support arm arm, be unlikely to during experiment to think and affect rat, also save computer and camera, thereby reduced greatly cost.And on three independent support arms of experimental provision of the present invention a lid is set all, makes it each the independent support arm of experimental provision of the present invention that links closely, thereby avoid testing the problem that rat runs away out when carrying out from experimental provision independence support arm of the present invention.
Beneficial effect of the present invention: device not only can be saved cost, solve expensive problem, but also can solve to a great extent that rat stands with one foot to the knee in the experimentation, climb in sidewall or the problem of directly from common Y arm lucite device, runing away out, and operation is very easy, from reducing to a great extent experimental period, increase work efficiency.
Description of drawings
Below in conjunction with the accompanying drawing illustrated embodiment, structure is described further, but protection domain of the present invention is not limited to this embodiment.
Fig. 1 is circuit theory diagrams of the present invention.
Fig. 2 is structural representation of the present invention.
Among the figure: 1a, 1b, 1c---independent support arm; 2a, 2b, 2c---intensive electrical network 3a, 3b, 3c---machine glass partition; 4a, 4b, 4c---bulb; 5a, 5b, 5c---lid; 6---transformer; 7e, 7f, 7g---switch; 8---power line; 9---the triangle electrical network.
Embodiment
As shown in Figure 1, three electrical networks (2a), (2b), (2c) are connected in parallel, and use respectively three switches (7e), (7f), (7g) independently to control separately electric current, three bulbs (4a), (4b), (4c) are connected in parallel, and use respectively switch (7a), (7b), (7c) independently to control separately electric current, triangle electrical network 9 usefulness switches (7d) are controlled separately electric current, and (4 a), (4b), (4c) and triangle electrical network (9) three are relation in parallel with three electrical networks (2a), (2b), (2c) and three bulbs again.For guaranteeing the safety of laboratory animal, the Control of Voltage of electrical network (2a), (2b), (2c) and triangle electrical network (9) is at 50V～70V DC voltage, and bulb (4) is controlled to be normal 220V voltage.
As shown in Figure 2, (2 a), (2b), (2c) are individually fixed on the bottom surface and sidewall of three independent support arms of experimental provision of the present invention, and with electric wire (8) connection transformer (6), use power line (8) that transformer (6) is connected power supply again with electrical network; Bulb (4) is fixed in the far-end of three arms of this usefulness Novel experiment device, and connects power supply with power line (8); Transparency glass plate (3) is placed in apart from (1) three arm far-end 10cm of independent support arm place; When experiment is carried out, lid (5) is placed in the top of independent support arm (1).
When experiment is carried out, switch (7) is placed apart from (1) 2 meter distant place of experimental provision independence support arm of the present invention, experimental animal rat is positioned in the independent support arm (1), will cover on independent support arm (1) with the lid (5) that independent support arm is complementary.
The experimental implementation step: rat is put into experimental provision of the present invention, allow rat adapt to 3～5min after, give suitably to shock by electricity may all explore and enter each independent support arm to rat till.When testing beginning, take rat place independence support arm as the independent support arm of safety, to rat place independence support arm and another independent support arm energising, the Delta Region also switches on, and animal runs away under shocking by electricity and keeps l0s or 30s once to test to the light district again.Then the 3rd the independent support arm in animal place tested for the original position of test next time next time.Run away to directly from the starting area after rat is shocked by electricity after place of safety or the energising that the disposable place of safety of running to is " correct response " in the 10s, if run away to any another the independent support arm without light, then be designated as wrong reaction.Carry out 20 training tests each experiment day, have in 20 experiments wherein that (greater than 90%) correct response then is designated as successfully more than 18 times.If success does not then continue test, until success then stops experiment, thereby estimate the rat learning ability by statistical method.Again rat is being tested after the 2nd day and 1 week after the success, write down after the rat success rate by statistical comparison to estimate the memory capability of rat.
Claims (3)
1. improved Y arm electronics maze experiment device, it is characterized in that the whole Y-shaped shape of maze experiment device, by three independent support arms with by the independent support arm (1a of three groove shapes, 1b, 1c) the central gore territory that jointly is connected to form of an end forms, each independent support arm (1a, 1b, a lid (5a who is complementary with independent support arm configurations is respectively arranged 1c), 5b, 5c), each independent support arm (1a, 1b, groove shape bottom surface 1c) and sidewall are covered with an intensive electrical network (2a separately, 2b, 2c), each independent support arm (1a, 1b, 1c) bottom surface and sidewall electrical network share a power line and separately respectively by a switch (7e, 7f, 7g) separately control; Triangle electrical network (9) also is equipped with in the groove shape bottom surface in middle triangle zone, and the electrical network in middle triangle zone is controlled with a switch (7d) separately; A machine glass partition (3a, 3b, 3c) respectively is equipped with in the inboard termination of the groove shape of each independent support arm (1a, 1b, 1c) the other end, a bulb (4a, 4b, 4c) is equipped with in every machine glass partition (3a, 3b, 3c) back, and each controls (7a, 7b, 7c) with a switch bulb (4a, 4b, 4c) in each independent support arm.
2. improved Y arm electronics maze experiment device according to claim 1 is characterized in that having fence on each lid (5a, 5b, 5c).
3. improved Y arm electronics maze experiment device according to claim 1 is characterized in that independent support arm (1a, 1b, 1c) the trisection radiant type of three groove shapes, and three mutual angles of independent support arm are 120 °.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105193247A CN102972309A (en) | 2012-08-15 | 2012-12-06 | Improved Y-arm electronic maze experimental device |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210290032 | 2012-08-15 | ||
| CN201210290032.0 | 2012-08-15 | ||
| CN2012105193247A CN102972309A (en) | 2012-08-15 | 2012-12-06 | Improved Y-arm electronic maze experimental device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102972309A true CN102972309A (en) | 2013-03-20 |
Family
ID=47846885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012105193247A Pending CN102972309A (en) | 2012-08-15 | 2012-12-06 | Improved Y-arm electronic maze experimental device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102972309A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103461166A (en) * | 2013-09-18 | 2013-12-25 | 浙江大学 | Three-arm maze device oriented to animal robot control training, and training method |
| CN104067956A (en) * | 2014-06-27 | 2014-10-01 | 山西医科大学 | Full-automatic rat feeding device applicable to behavior of rats and mice |
| CN105230520A (en) * | 2015-07-25 | 2016-01-13 | 南昌航空大学 | Full-automatic rat maze behavior training system |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5054427A (en) * | 1989-09-21 | 1991-10-08 | Hoover Judith L | Insertable stacking pet toy maze |
| US5868102A (en) * | 1997-10-31 | 1999-02-09 | Petty; Gregory | Construction for a pet cat with variable internal ambient light levels |
| US20030024482A1 (en) * | 2001-08-06 | 2003-02-06 | Vijay Gondhalekar | Programmable electronic maze for use in the assessment of animal behavior |
| CN1817325A (en) * | 2006-02-21 | 2006-08-16 | 沈阳医学院 | Mouse hearing and vision memory model and intelligent action inspecting system |
| US20100206241A1 (en) * | 2009-02-06 | 2010-08-19 | J.W. Pet Company, Inc. | Small animal entertainment, exercise and interaction structure |
| CN101884306A (en) * | 2010-07-15 | 2010-11-17 | 李建民 | Animal behavior memory test maze device |
-
2012
- 2012-12-06 CN CN2012105193247A patent/CN102972309A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5054427A (en) * | 1989-09-21 | 1991-10-08 | Hoover Judith L | Insertable stacking pet toy maze |
| US5868102A (en) * | 1997-10-31 | 1999-02-09 | Petty; Gregory | Construction for a pet cat with variable internal ambient light levels |
| US20030024482A1 (en) * | 2001-08-06 | 2003-02-06 | Vijay Gondhalekar | Programmable electronic maze for use in the assessment of animal behavior |
| CN1817325A (en) * | 2006-02-21 | 2006-08-16 | 沈阳医学院 | Mouse hearing and vision memory model and intelligent action inspecting system |
| US20100206241A1 (en) * | 2009-02-06 | 2010-08-19 | J.W. Pet Company, Inc. | Small animal entertainment, exercise and interaction structure |
| CN101884306A (en) * | 2010-07-15 | 2010-11-17 | 李建民 | Animal behavior memory test maze device |
Non-Patent Citations (5)
| Title |
|---|
| 丁杰等: "慢性束缚应激大鼠Y迷宫实验变化及逍遥散对其的调节", 《第二次全国中西医结合诊断学术研讨会论文集》 * |
| 江刚等: "学习记忆过程中磷酸化的CREB在大鼠脑纹状体内的表达", 《中国临床康复》 * |
| 江刚等: "脑纹状体边缘区注射MK-801对大鼠逃避性长期记忆的影响", 《中国行为医学科学》 * |
| 王跃春等: "动物学习记忆能力的Y-型迷宫测试法(综述)", 《暨南大学学报(自然科学与医学版)》 * |
| 陈旭红等: "pERK1/2在大鼠脑内的分布及Y迷宫训练后的时程变化", 《中国行为医学科学》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103461166A (en) * | 2013-09-18 | 2013-12-25 | 浙江大学 | Three-arm maze device oriented to animal robot control training, and training method |
| CN104067956A (en) * | 2014-06-27 | 2014-10-01 | 山西医科大学 | Full-automatic rat feeding device applicable to behavior of rats and mice |
| CN104067956B (en) * | 2014-06-27 | 2015-12-30 | 山西医科大学 | One is applicable to the ethological full-automation of large mouse and throws mouse device |
| CN105230520A (en) * | 2015-07-25 | 2016-01-13 | 南昌航空大学 | Full-automatic rat maze behavior training system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203167789U (en) | Improved Y arm electronic maze experimental device | |
| CN102972309A (en) | Improved Y-arm electronic maze experimental device | |
| CN202649448U (en) | Large user information collection terminal detection apparatus completely simulating scene | |
| Volkov et al. | Circadian variations in biologically closed electrochemical circuits in Aloe vera and Mimosa pudica | |
| Volkov et al. | Anisotropy and nonlinear properties of electrochemical circuits in leaves of Aloe vera L. | |
| WO2024025266A1 (en) | Smartphone storage and charging device | |
| CN106526385A (en) | Semi-active laser seeker performance test method and apparatus thereof | |
| CN102868314B (en) | Multi-waveform impact current generator | |
| CN103996338B (en) | Intelligent open type multifunctional Power Electronic Experimentation device | |
| CN207626791U (en) | A kind of multifunctional electric practice teaching table | |
| CN102818950B (en) | Multi-waveform switching module for lightning stroke surge current testing system | |
| CN204742179U (en) | Detect social avoidance behavior's of rodent device | |
| Gater et al. | Connecting spiking neurons to a spiking memristor network changes the memristor dynamics | |
| CN109691396A (en) | Improve Y arm electronics labyrinthine system | |
| CN209543629U (en) | A kind of connection box of electric energy meter actual training device | |
| CN102005150A (en) | Power supply teaching experimental system | |
| CN205230432U (en) | Medical treatment electronic engineering experimental box | |
| CN210925004U (en) | Electric automobile fault diagnosis teaching equipment | |
| CN105702141A (en) | Live trimming body feeling system | |
| CN106710394A (en) | Portable Internet of Things simulation power station | |
| CN203552547U (en) | Solar photovoltaic generating experiment system | |
| CN205121969U (en) | Real standard platform of intelligent substation secondary system test | |
| CN202617984U (en) | Multipath mouse jumping platform shuttle video comprehensive analytical system | |
| CN109932532B (en) | Platform and method for line induction electric test | |
| CN105280056B (en) | A kind of traffic simulation experiment external member |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130320 |