CN103170024A - Normovolemic dilution autoblood collection and reinfusion system and normovolemic dilution autoblood collection and reinfusion device - Google Patents
Normovolemic dilution autoblood collection and reinfusion system and normovolemic dilution autoblood collection and reinfusion device Download PDFInfo
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Abstract
The invention discloses a normovolemic dilution autoblood collection and reinfusion system and a normovolemic dilution autoblood collection and reinfusion device. The system is composed of a pipeline system, a dynamic system, a monitoring and alarming system, a blood-storage system and a computer control platform. When the system works, autoblood evenly blended with anticoagulation is stored in a blood-storage bag, at the same time diluent is infused in a blood vessel, and thus the purposes of blood sampling and hemodilution are achieved; when needed, the stored autoblood is infused back to a patient, and thus the purpose of reducing loss of hemoglobin is achieved. The system is controlled and operated by a computer, the monitoring and alarming system is arranged in the system, and thus safe operation is guaranteed. The dynamic system in the system can be controlled independently to conduct liquid infusion, and a pressure monitoring device can supply pressure data. The normovolemic dilution autoblood collection and reinfusion device is divided into a main engine and a control panel and is composed of a pump component, a mentoring component, a pipeline control card component, a control panel and a table. By means of the normovolemic dilution autoblood collection and reinfusion system and the normovolemic dilution autoblood collection and reinfusion device, normovolemic dilution autoblood collection and reinfusion can be performed automatically and safely, the workload of doctors is reduced, efficiency is improved, risk is avoided, and further the normovolemic dilution autoblood collection and reinfusion system and the normovolemic dilution autoblood collection and reinfusion device can be used as a infusion control platform and for pressure monitoring.
Description
Technical field
The present invention relates to a kind ofly hold dilution process by grade and complete system and the relevant apparatus that gathers and feed back from body blood, and can utilize simultaneously this system to build and carry out the peri-operative central venous infusion management and control.
Background technology
Blood used in clinic relates generally to from body blood and allosome blood two aspects.Infusion allosome blood may bring a lot of problems to the patient, and as allergy, heating, disease propagation etc., no matter be doctor or patient, family members wish to avoid or reduce infusion allosome blood as far as possible, this is the important clinical problem of medical circle discussion and research for a long time.Simultaneously, amount of bleeding and allogeneic transfusion amount are one of major criterions of estimating medical level, and less application allosome blood indicates better medical skill and medical integrated management usually.In addition, allosome blood is a kind of non-renewable medical resource, and it gathers, preserves and use the mechanism by specialty to complete, and need to employ a large amount of social resources, also needs a large amount of volunteer doner of bloods' support energetically simultaneously.Allosome blood is the important leverage resource that curative activity is carried out smoothly; in case be subject to the situation impacts such as blood donor's minimizing, blood used in clinic increase, emergency burst; clinical position will be subject to severe jamming; time-out or the necessary curative activity of termination happen occasionally because of " blood is waste ", and this gives needs the patient who inputs allosome blood redemption health and lives to bring serious threat.Rationally using and reducing use is to alleviate allosome blood key problem in short supply.This shows, it is not only medical problem that allosome blood uses, and is also social problem, and economic problems concern medical safety, have been subject to the extensive concern of the whole society.
In surgical procedures; autotransfusion, reduce hemorrhage and intraoperative hemorrhage to reclaim be the important technique measure of blood samples of patients protection; everybody recognizes; rationally the above many kinds of measures of integrated application can reduce the use of even avoiding allosome blood; the development of correlative technology field will produce positive impact to the blood used in clinic problem, and the integral body that promotes medical level improves.
Autotransfusion is paid close attention to by everybody very early, just began to adopt before 170 years, but because the worry of post-transfusion hepatitis is promoted the use of gradually, the research of association area also deepens continuously, and wishes that it becomes the effective means that reduces the blood transfusion of allosome blood after 1970.At present, autotransfusion mainly contains dual mode, and a kind of is to preserve from body blood before art, and another kind is that acute before the operation beginning waited and hold dilution and transfuse blood from body blood.Front a kind of mode was once widely used at western developed country the eighties, but, medical treatment complicated due to flow process drops into more, the multiple unfavorable reasons such as cost performance is not high, blood waste, use obviously and reduce, only account at present 2.5% of U.S.'s blood drawing total amount, therefore, everybody the dilution autotransfusion mode of holding such as places on to hope.
The present invention relates generally to etc. and to hold system, technology and the device that dilution is preserved and fed back from body blood, and based on peri-operative central venous infusion management, the control system of this system.at the anesthesia initial stage Deng holding the dilution method collection from body blood, before the operation beginning, drain is set the autoblood of unit in the special blood storage bag that is filled with anticoagulant, give simultaneously crystal or the colloidal solution of the suitable volume of patient's infusion, to guarantee the stable of the stable and life state of blood volume in patient body, the patient blood hemoglobin concentration dilution is to the setting level, if hemorrhagely after operation beginning cause hemoglobin concentration to descend reaching when estimating to feed back concentration starting intraoperative autologous blood transfusion, if reaching all the time, hemoglobin concentration do not estimate to feed back concentration, will be before operation finishes with intraoperative autologous blood transfusion to the patient, reach the minimizing operative hemorrhage, promote the therapeutic goal of postoperative hemoglobin concentration.A large amount of clinical experiments is verified; the appearance dilution process such as employing are completed from the collection of body blood; owing to having made the blood Macrodilution before the operation beginning; reduced the concentration of hemoglobin in unit volume blood; reduced the hemoglobin loss that intraoperative hemorrhage causes; reach the purpose of blood conservation, reduce infusion rate or the infusion amount of allosome blood, help to avoid or reduce the various risks of using allosome blood to bring.
Along with holding the further investigation of diluting rear body compensation about waiting, find that body can tolerate to a great extent acute the grade by multiple self-regulation mode and hold dilution, operating process is that safety is controlled, even if be also the same for elderly patient and cardiovascular patient.Research is also found; cause the body compensatory mechanisms such as heart stroke increases, blood viscosity descends, the hemoglobin oxygen dissociation curve moves to right after hemodilution; the body microcirculating state improves; the perfused tissue amount increases; help the protection of the important organs such as Rhizoma Atractylodis Macrocephalae midbrain, lung, heart, but blood coagulation system is not caused harmful effect.Therefore, wait to hold to dilute not only can reach the purpose of blood conservation, or a kind of effective means of the many Organoprotectives of perioperative.Therefore, wait in view of acute the safety of holding dilution process, and the effectiveness aspect blood conservation, Organoprotective, this method is written in the autotransfusion guide.
Although be worthy to be popularized Deng holding dilution autotransfusion mode, the clinical practice situation is undesirable, and main cause is the risk that the inconvenience in practical operation, the impact that anesthesia management is caused and misoperation cause.At present, owing to lacking higher dilution, the blood sampling apparatus of automatization's degree of being controlled to, implementation process relies on manually-operated fully, and blood sampling, blood transfusion path also are not quite similar, and efficient is very low.At present, blood sampling mainly depends on the gravity drainage mode, if adopt the Vein Tube blood sampling tube, 2 unit whole bloods of every collection approximately need 15 minutes, and efficient is not high, has extended anesthesia duration, has waited for operating time, and amount of dilution is larger, and time expand is more; If adopt the arterial intubation blood sampling tube, though blood sampling speed is improved, the Arterial system rapid, high volume is lost blood, from vein rapid, high volume infusion fluid, easily cause hemodynamics sharply to change, impact anesthesia is steady, and relevant organ functional lesion appears in the patient who easily brings out pulmonary insufficiency.Simultaneously, because blood need to there is no anticoagulant therebetween and sneak into, easily cause thrombosis by long and narrow pipeline drainage to the blood storage bag near ground level, cause blood waste and blood transfusion risk.In addition, because blood collection procedure must be completed by the anaesthetist, the anaesthetist is when controlling blood sampling, transfusion speed coupling, want the continual blood storage bag of rocking, guarantee the abundant mixing of blood and anticoagulant, meanwhile also will drop into energy and be used for anesthesia management and anesthesia monitoring, work load rolls up, energy disperses, and easily causes the work careless omission, causes risk.For example, if observe untimelyly, drainage volume surpasses the standard of blood storage bag, will cause the anticoagulant relative deficiency, brings out thrombosis in storage blood bag.And for example, because blood sampling efficient is low, length consuming time, when a variety of causes requires operation to begin as early as possible, blood sampling work will have to stop, and not reach predetermined dilution rate, affect therapeutic effect.
In order to improve from body blood acquisition mode, improve collecting efficiency, must abandon traditional gravity drainage mode, rely on automation equipment, accurately control amount and speed from the collection of body blood, diluent infusion, raise the efficiency, reduce the impact on patient's recurrent state and organ function, and fully the anaesthetist is freed from loaded down with trivial details operation, avoid the human error.At present, the U.S. has the inventor to design the simple mechanical type negative pressure device that improves blood sampling efficient, only relates to the change of drainage way, and is very limited to the improvement that integral body is controlled.
At present, the automatization's management and control field that still there is no clinically the appearance dilution autotransfusion methods such as ripe system, technology, device are used for.Central vein catheter is the transfusion path of big-and-middle-sized operation necessity, associative operation is the important step of anesthesia management, the present invention design wait appearances to dilute from the collection of body blood, the special two-chamber central vein catheter of feedback system's dependence to carry out blood collection and feedback, on the basis that does not increase anesthesia doctor operation bidirectional, help to adopt control and the automatization of blood transfusion process, the transfusion power-equipment that provides by this system and control appliance can also be completed the control to infusion flow and the flow velocity of multiple medicine, also can be used for the monitoring of central venous pressure.This invention designed system can promote clinical expansion and the use of this autotransfusion mode, is applied to simultaneously perioperative fluid infusion management and central venous pressure monitoring, can be built into the management and control platform of Autoblood collection, blood transfusion and peri-operative central venous infusion.
Summary of the invention
Adopt the gravity drainage mode of poor efficiency in view of at present clinical first-class appearance dilution, rely on manually-operated and control fully, multiple unfavorable factor affects popularization and the safety applications of the method, for this reason, main purpose of the present invention is to provide the system of the appearance dilution Autoblood collections such as automatization completes, blood transfusion, and the device that matches, comprise pipe-line system, dynamical system, monitor and alarm system, blood stocking system and computer control platform.
Blood collection of the present invention and diluent infusion rely on the Double-laparoscope central venous catheter of inserting patient's central vein, a relatively thick tube chamber can draw blood or feed back by the side conduction hole of conduit, and a relatively thin tube chamber can inject central vein with diluent or medicine by the stomidium of catheter tip.Thicker tube chamber can guarantee to provide desirable blood drainage amount under lower tube chamber negative pressure state, and higher blood sampling efficient and blood cell protection fully are provided.
The supporting pipeline of Double-laparoscope central venous catheter and main frame is connected.The pipeline that blood is drawn or fed back is called transducer potector, and far-end is connected with blood storage bag, and the centre is connected with two secondary duct by side opening, and the secondary duct far-end connects anticoagulant syringe and transfusion bag; Corresponding, the pipeline that diluent injects is called liquid line, and far-end is connected with the diluent reservoir bag, and the centre is connected with secondary duct by side opening, and the secondary duct far-end connects the paramedicines syringe.
In pipeline, the driving of liquid relies on the dynamical system that is made of 4 pump installations to complete, and each two of occlusion pump and standardize solution infusion pump adopt known technology and parts, and the flow velocity of every pump, flow or the flow direction are by the computer system control of controlling platform.
The traveling zone of pipeline in main frame is provided with many places mechanicalness control card, and control card is closed resistance stopped pipe road, stops liquid flowing in pipeline, and the keying of control card is controlled according to different operation modes and monitoring, alarming situation by controlling platform.In pipeline traveling process, pressure and gas controlling device are set, the monitoring device data are sent to the control platform, control platform according to the keying of data cases feedback control many places pipeline control card, to guarantee the safety of blood sampling and blood transfusion process.
Gathering blood mixes with anticoagulant in transducer potector, mixing in occlusion pump extrusion process, finally be stored in blood storage bag, blood storage bag is placed in the storage blood storehouse of laying shaking table, shaking table is controlled by controlling platform, uninterruptedly rock to the terminal procedure of transfusing blood in the blood sampling beginning, promote anticoagulant and blood mixing, thrombosis in preclude blood.
Control panel consists of by setting adjusting parts, display screen and computer.By regulating the button on control panel, the doctor can set the concrete numerical value such as total blood sampling volume, blood sampling speed, diluent infusion total amount, diluent flow velocity according to the blood sampling prediction scheme, and pressure alarm can also be set.The different working modes that the doctor presets in can selection equipment, as blood sampling pattern, blood transfusion pattern, infusion mode etc., under different mode, occlusion pump turns to, the pipeline control card opens and closes and set in advance, and can conveniently start relevant action.Display is used for showing parameters, alarm condition and the equipment running status that needs are observed or adjusted.Computer system is completed data input, computing, output according to program prepared in advance, controls the running of whole equipment.
By above part consist of wait to hold dilution from body blood gather, the feedback system, can complete setting, enforcement, monitoring and the management and control of adopting the blood transfusion process, the operation and the energy that farthest reduce the doctor disperse, complete accurate data setting and scheme implementation, and give Real-Time Monitoring, send danger warning and stop running, give wait appearances dilution from body adopt blood transfusion operate provide convenience, safe guarantee.
Simultaneously, in blood sampling, time beyond the blood transfusion process, system can control separately four pump installations, foundation transfusion speed is set, complete the quantitative infusion of traditional fluid infusion and special medicine, consist of peri-operative central venous infusion management and control platform.Gas enters owing to providing, pressure alarm, and it is safer that infusion process will become.The pressure sensor device that arranges in system not only can provide pressure monitoring and the warning in blood collection procedure, and the central venous pressure force data can also be provided, and carries out the hemodynamic monitoring in anaesthesia process.
Beneficial effect of the present invention is.
1, invention design etc. hold dilution from body blood gather, the feedback system, can hold the dilution prediction scheme and set blood sampling flow rate and dilution flow rate flow according to waiting, accurately control dilution, reduce operation to hemodynamic impact.
2, system according to setting, completes accurately automatically controlling of blood sampling and blood transfusion process, and the operation and the energy that reduce the Anesthetist disperse, and ensure operation and Anesthetic safety.
3, it is available that there is multiple predetermined registration operation pattern in system, facilitates doctor's adjusting device quickly.
4, pressure, the gas warning system of system's setting by computer system automatic open close pipeline control card, guarantee the processing safety under different mode.
5, the Double-laparoscope central venous catheter of system's employing can be used for conventional peri-operative central venous infusion management, does not additionally increase to anaesthetize to put to manage to operate.Owing to can four infusion pump be controlled separately, system also can take into account and consist of medium-sized vein transfusion management and control center, facilitates anesthesia management.
6, system provides the central venous pressure force data, carries out the hemodynamic monitoring in anaesthesia process.
Description of drawings
Accompanying drawing described herein is used to provide a further understanding of the present invention, consists of the application's a part, and illustrative examples of the present invention and explanation thereof are used for explaining the present invention, do not consist of improper restriction of the present invention.
The two-chamber central vein catheter structure chart that Fig. 1 the present invention adopts and insert schematic diagram.
Fig. 2 host structure chart of the present invention.
Fig. 3 control panel structure chart.
Fig. 4 system works ideograph.
Work schematic diagram under Fig. 5 main frame dilution blood sampling mode state.
The work schematic diagram under state is kept in the protection of Fig. 6 main frame pipeline.
Work schematic diagram under Fig. 7 main frame infusion mode state.
Work schematic diagram under Fig. 8 main frame blood recovery mode state.
Fig. 9 occlusion pump safety monitoring warning system hierarchical schema figure.
Negative pressure, high pressure, air inlet under Figure 10 main frame dilution blood sampling mode state are reported to the police and are shut down schematic diagram.
High pressure under Figure 11 main frame infusion mode state, air inlet are reported to the police and are shut down schematic diagram.
High pressure, air inlet under Figure 12 main frame blood transfusion mode state are reported to the police and are shut down schematic diagram.
Figure 13 computer control schematic flow sheet
101-central venous catheter in figure, the 102-stomidium, the 103-side opening, the 104-fixed-wing, 105-transducer potector branch, 106-liquid line branch, the 107-transducer potector, the 108-liquid line, the 109-pipe joint, 110-standardize solution pump branch line A, 111-standardize solution pump branch line B, 112-infusion connecting tube road A, 113-infusion connecting tube road B, 114-blood storage bag connecting line, the 115-blood storage bag, 116-diluent bag, the 117-transfusion bag, 118-anticoagulant syringe, 119-paramedicines syringe, 201-occlusion pump A, 202-occlusion pump B, 203-standardize solution infusion pump A, 204-standardize solution infusion pump B, 205-pressure monitoring device A1, 206-pressure monitoring device A2, 207-pressure monitoring device B, 208-pipeline control card A1, 209-pipeline control card A2, 210-pipeline control card B, the 211-shaking table, 301-occlusion pump A flow velocity display screen, 302-occlusion pump B flow velocity display screen, 303-standardize solution infusion pump A flow velocity set and display screen, 304-standardize solution infusion pump B flow velocity set and display screen, 305-blood sampling total amount set and display screen, 306-dilution total amount set and display screen, 307-alarm indicator screen, 308-pattern set and display screen, 309-numerical value adjusting knob, the 310-trim button, the 311-fast forward button, 312-master's ACK button, 313-start stop button, 314-gas controlling device A, 315-gas controlling device B, 316-transfusion bag support, 317-screen ACK button.
The specific embodiment
Hereinafter with reference to accompanying drawing, embodiments of the invention are described in detail, only for the present invention is described, rather than in order to limit protection scope of the present invention.
Double-laparoscope central venous catheter and pipeline are prepared to select in patient's neck, under clavicle or femoral vein is inserted Double-laparoscope central venous catheter in the puncture mode, as an example of the internal jugular vein indwelling pipe example (Fig. 1), the conduction hole of side (103) draws blood or feed back by thicker tube chamber, most advanced and sophisticated stomidium (102) enters vein by thinner tube chamber with diluent or liquid medicine injection, with suture, fixed-wing (104) is fixed on patient skin, keeps catheter position.Supporting pipeline and monitoring, alarming accessory need be placed in respectively main frame (Fig. 2) and control panel (Fig. 3).With pipe joint (109), the transducer potector branch (105) of Double-laparoscope central venous catheter is connected 106 with liquid line branch) be connected 107 with transducer potector respectively) be connected 108 with liquid line) connect.Transducer potector and liquid line and attached standardize solution transfusion branch line thereof, infusion connecting tube road, pressure monitoring device are all packed in main frame shown in Figure 2 according to mode shown in Figure 4.Each pipeline far-end connects respectively anticoagulant syringe (118), paramedicines syringe (119), blood storage bag (115), diluent bag (116) and transfusion bag (117).Pipeline trunk (106,107) embeds in the squeezing groove of occlusion pump, and (112,113,114 embed in the associated pipe control card according to Fig. 4 its Main Branches.Will be with gas in liquid emptying pipeline after pipeline installs.Hold dilution from body blood gather, setting completed for the feedback system, standby.
The formation of control panel and setup control panel surface mainly consist of by setting adjusting button and display screen, and the surface placement of control panel as shown in Figure 3.Press the other confirmation button of display screen, the flicker of display screen displaying contents, related setting is in state of activation, at this moment can set and regulate by the button on control panel.Regulating button (309), trim button (310) by left rotation and right rotation numerical value can the regulating system operating parameters, after setting completed, presses main ACK button (312) and completes setting.After pressing startup stop button (313), will start each mechanical part of main frame according to the duty that arranges and pattern, again pressing turns round when starting stop button (313) stops.After activating standardize solution transfusion display screen, press simultaneously fast forward button (311) and ACK button (312), can start standardize solution infusion pump (303,304) and advance fast the interior liquid of syringe.Alarm indicator can display alarm type and position with (307), and corresponding carrying out activated screen by the confirmation button (317) on sub-screen side after adjusting.Press again main ACK button (312) and can eliminate warning.After pattern set and display screen (308) activates screen by screen ACK button (317), regulate button (309) by rotation numerical, can the selective system mode of operation, press start stop button (313) can start the mode of operation of setting, again press and suspend existing mode of operation.
The purpose of blood conservation mode system works is autohemic drain, storage and feedback, and blood conservation is extremely important.The anticoagulant of filling line is in occlusion pump (201) extrusion process and the abundant mixing of pipeline inner blood, inflow is placed in the blood storage bag on shaking table, and after the blood sampling beginning, shaking table is under the state of vacillating now to the left, now to the right all the time, until the explanation of blood transfusion process, by preventing thrombosis with upper type.Because erythrocyte excessively can break in lower pressure environment, cause haemolysis, pressure monitoring device (205) is with the negative pressure state in main line in the Real-Time Monitoring blood collection procedure, during lower than the safe condition of-10mmHg, to trigger low pressure alarming, stop blood collection procedure, restart blood sampling after need readjusting, arranging.
The connection of standby host state pipeline, aerofluxus, duty and pattern are set after, can be in the standby host state by initialization system, at this moment, 4 pumps of main frame all stop fortune dress, 3 pipeline control cards are all closed, shaking table is static, in pipeline, liquid all remains static.
calculate predetermined blood sampling volume Deng packed cell volume or the hemoglobin concentration of holding dilution Autoblood collection duty and prepare before according to operation in patients dilution, at control panel (Fig. 3) adjusted blood sampling total amount (305) and occlusion pump A flow velocity (301) to predetermined value, regulate dilution total amount (306) and occlusion pump B flow velocity (302) to predetermined value, computer will be according to the flow velocity of occlusion pump A (201) velocity of blood flow automatic setting standardize solution infusion pump A (203), press start stop button (313), Deng appearance dilution Autoblood collection system's entry into service (Fig. 5).
In the transducer potector traveling, pipeline control card (208) opening, (209) are closed, occlusion pump A (201) is running counterclockwise, with the active ways of negative pressure drainage with the side opening introduction pipeline of central vein blood from central venous catheter, standardize solution infusion pump A (203) sneaks into anticoagulant in blood in proportion, abundant mixing in occlusion pump A (201) extrusion process, by anticoagulant in the final drain of body blood enters to be placed in blood storage bag (115) on shaking table (211).Shaking table i.e. startup after blood collection procedure begins waves antithrombotic, automatically stops until the blood recovery process all finishes the rear.
Pipeline control card (210) in the liquid line traveling is open, and occlusion pump B (202) is running counterclockwise, and the diluent in diluent bag (116) will inject patient's central vein by the stomidium of central vein pipe.
After reaching predetermined blood sampling volume, wait to hold to dilute to stop from body blood gatherer process, system automatically enters the pipeline protection and keeps state (Fig. 6) running.
(Fig. 6) under state kept in the protection of pipeline protection maintenance work state pipeline; pipeline control card (208) is closed; pipeline control card (209,210) is open; occlusion pump (201) running clockwise, (202) running counterclockwise; all with the flow velocity of 10ml/ hour, the liquid low speed in diluent bag and transfusion bag is pumped into central vein pipe and dark vein; to avoid thrombosis in pipeline and central vein tube chamber, guarantee the lasting unobstructed of system pass.At this moment, two standardize solution infusion pump (203,204) are in the state of shutting down.
The transfusion duty is when system uses as peri-operative central venous infusion management and control platform (Fig. 7), pipeline control card (208) is closed, pipeline control card (209,210) is open, two occlusion pumps (201,202) and two standardize solution infusion pump (203,204) can independent coutroi velocities, but in order to guarantee the lasting unobstructed of pipeline, occlusion pump (201,202) is set flow velocity and is not allowed lower than 10ml/ hour.Occlusion pump (201,202) is generally as conventional liq, and as the infusion of Glucose Liquid, normal saline or plasma substitute goods, flow is in the upper setting of control panel (301 or 302).Anticoagulant syringe (118) can be changed to paramedicines syringe (119), standardize solution infusion pump (203,204) is used as the liquid input of concentration configuration in accordance with regulations such as vasoactive drug, anesthetic and sedative drugs product, flow can be set at control panel (303,304), and can pass through trim button (310) fine setting flow setting value, minimum flow is regulated unit can be to 0.1ml/ hour, and can advance fast syringe by fast forward button (311), liquid will enter central vein fast.
The blood recovery duty when needs of patients feed back to gather from body blood the time, set interface (308) by the pattern of control panel and select blood recovery pattern (Fig. 8), liquid line is kept former operating condition under this pattern, in transducer potector, pipeline control card (208) is open, pipeline control card (209) is closed, occlusion pump A (201) starts running clockwise, to be fed back to patient's central vein from body blood in blood storage bag, transfusion speed and total amount need to set by (301,305) on control panel.Blood recovery is after reaching predetermined value, and pipeline control card (208) is closed, and pipeline control card (209) is open, and occlusion pump A (201) reduced flow velocity to 10ml/ minute, and transducer potector enters pipeline protection maintenance work state automatically.
In safety monitoring warning system and termination of pumping status system operation process, three place's pressure monitoring devices (205,206,207) are set (Fig. 2) in pipeline traveling circuit, implement monitoring pipeline inner pressure situation of change, hypertonia or too low over after setting safety value, to start sound and screen flicker and report to the police, relevant infusion pump shuts down automatically.Two place's gas controlling devices (314,315) are set (Fig. 3) on control panel, if gas entrance starts sound and screen flicker and reports to the police, relevant infusion pump also will shut down automatically, avoid gas input human body.Two standardize solution infusion pump inside arrange alarm for high voltage, can start sound and screen flicker and report to the police.Safety monitoring warning system level as shown in Figure 8, concrete alarm content will show control panel alarm indicator screen (307) is upper.In case warning termination of pumping event occurs, and operator are check system carefully, removes risk factor, then the restarting systems running.Under different mode, the termination of pumping state that different warning classifications cause is different, is described below respectively.
Under appearance dilution blood sampling mode state, no matter low pressure alarming occurs in pressure monitoring device (205), alarm for high voltage occurs in (206 and or 207), or air inlet occurs and reports to the police in gas controlling device (314,315), except the shaking table external system that still keeps turning round will quit work (Figure 10) comprehensively, alarm content is in control panel (307) upper concrete demonstration.At this moment, pipeline control card (208,210) will be closed from open automatically transferring to, and in system, 4 infusion pump all shut down, and blood sampling and dilution operation stop.After hazard detection, eliminating, restart, system will preferentially give tacit consent to former dilution blood sampling entry into service will be set, and also can reset rear running.
Report to the police under the infusion mode state, 4 infusion pump are not related each other, will cause relevant infusion pump termination of pumping according to concrete alarm content, and the infusion pump that is under normal condition works on, and alarm content is in the upper concrete demonstration of control panel (307).For example, infusion mode state downforce monitoring device B (207) occur alarm for high voltage and or gas-monitoring B (315) air inlet occurs reports to the police, occlusion pump B (202) meeting termination of pumping, pipeline control card (210) will be closed from open automatically transferring to, (202) transfusion controlled of pump will stop, other infusion pump do not quit work (Figure 11).Two standardize solution infusion pump generation alarm for high voltage, relevant infusion pump will quit work, and other infusion pump and pipeline control card duty are unaffected.
Report to the police under the blood transfusion mode state, as pressure monitoring device A1 (205) occur alarm for high voltage and or gas-monitoring A (314) air inlet occurs reports to the police, only occlusion pump A (201) meeting termination of pumping, pipeline control card (208) will be closed from open automatically transferring to, (201) blood transfusion controlled of pump will stop, not stopping infusion work of other infusion pump (Figure 12).
The computer control flow process
Computer in main frame has the general framework in this area, comprises processor, memorizer, input part (knob, button) and efferent (display screen).Computer control system is accepted the setting of artificial input and is regulated information, through Computing, to the plant equipment on main frame, as pump, pipeline control card, shaking table, controls.After monitoring system is sent warning message, relevant information will be inputted computer automatically, and computer will be controlled machinery automatically according to the flow process that sets, until artificial the adjustment starts mechanical system running (Figure 13) after elimination is reported to the police again again.Computer system can realize automatically controlling by software, and those skilled in the art use prior art according to the systemic-function needs, the establishment predetermined software programs, and in the device production phase is stored in the memorizer of computer-internal, for operation after processor.Software can start operation automatically after input part arranges, also can automatically move after the warning message input, and control system and device enter safe condition.Pump, pipeline control card and shaking table are the machinerys of final performance effect in control flow.
Central venous pressure monitoring is due to pipeline and central vein UNICOM, and the pressure monitoring device (205,207) that is in pipeline can be used for continuing or the discontinuous measurement central venous pressure, and this is the important hemodynamic index in anesthesia management.
The above is only exemplary embodiments of the present invention, can or delete corresponding handling process based on enforcement interpolation of the present invention.For a person skilled in the art, the present invention can have various changes and variation.All any modifications of doing based on exemplary embodiments of the present invention, be equal to displacement, improvement etc., within protection scope of the present invention all should be included in.
In addition, those skilled in the art should be understood that, above-mentioned the present invention is comprised of the pipe-line system that comprises central vein catheter, dynamical system, monitor and alarm system, blood stocking system and computer control platform 5 parts, and related material, device and mechanical system all can realize with general design.The input that the computer control platform relates to, calculating and output can be realized by the executable program code of accountant, perhaps be made into respectively each integrated circuit modules and realize.Like this, the present invention is not restricted to the combination of any specific hardware and software.
The above is only the preferred embodiments of the present invention, is not limited to the designed system of the present invention, and for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (11)
1. one kind is waited the appearance dilution from the system of the collection of body blood, feedback, automatically complete dilution, collection, anticoagulant and the storage of blood under computer control, feed back to the patient when clinical the needs, this system can also be as peri-operative central venous infusion management and control platform and central venous pressure monitoring, and this system comprises:
The computer control platform, control platform and be made of input setup control panel and computer, computer is accepted the information of control panel and warning system, by internal processor control system operating condition, and relevant information is shown, monitor adjustment for operator;
Dynamical system, associated pump device are arranged in pipeline traveling path, promote pipeline during the pump running and syringe inner blood, diluent and medicinal liquid flow, and operating condition is controlled by the computer control platform;
Monitor and alarm system is for guaranteeing the whole system safe handling, to gas, pressure index Real-Time Monitoring in pipeline, in case the generation danger warning, the computer control platform is with automatic motivation of adjustment working state of system, and the primer liner control device, resistance stops liquid flow, guarantees safety;
The blood stocking system, the blood of collection adds anticoagulant, stores in blood storage bag;
Pipe-line system, be the path of blood, diluent and medicine traveling, patient's vein, drug injector, transfusion bag and blood storage bag are coupled together, in pipeline, liquid flow is driven by dynamical system, state in pipeline is monitored by monitor and alarm system, and the control device that can hinder the stopped pipe road is set.
2. system according to claim 1, is characterized in that, pipe-line system is comprised of conduit, main line, branch line, connecting line, it is the path of blood, diluent or the traveling of medicine body, preserve in blood storage bag from body blood, and be placed on shaking table, blood is in flow regime; Blood collection and diluent infusion rely on the conduit of inserting the patient vessel, and blood is drawn or fed back, and diluent is inputted blood vessel; Dynamical system is made of pump installation, for blood drainage and blood transfusion and infusion provide power, also provides power for injecting anticoagulant and medicine.
3. system according to claim 1, it is characterized in that, monitor and alarm system is made of pressure monitoring device, gas controlling device and pipe controller, automatically adjust the keying of associated pipe control device by the computer control platform, during resistance stopped pipe road, the interior liquid flow of pipeline stops, and reaches the purpose of monitoring, warning, security control.
4. system according to claim 1, is characterized in that, a plurality of pump installations of setting can independently be controlled, as venous transfusion management and control platform; If conduit is connected with central vein, can be used for the central venous pressure monitoring.
5. system according to claim 1, is characterized in that, the computer control platform is made of input setup control panel and computer, by control panel initialization system operating condition, and real-time display system operating condition, alarm condition; Computer is accepted the information of control panel and warning system, turns round by computer-internal processor control system; The workflow of control system is: computer accepts to set the input message of adjusting parts and the monitoring information of monitoring component, according to program prepared in advance, carry out computing by computer, judge, output order, mechanical part on control device, the i.e. drive manner of pump installation, pipe controller, shaking table.
6. one kind is waited the appearance dilution from the device that body blood gathers, feeds back, and can be divided into main frame and control panel two large divisions, is comprised of pump parts, monitoring component, pipeline control card parts, control panel, shaking table;
The pump parts are power resources, are comprised of occlusion pump and standardize solution infusion pump, adopt known technology and parts;
Monitoring component and pipe controller synergism are for system and equipment operation provide safety guarantee;
Control panel regulates parts by display unit, setting and computer processor forms;
Shaking table adopts known technology and parts, waves the blood that makes in blood storage bag and is in flow regime.
7. device according to claim 6, it is characterized in that, device is take electric power as the energy, pump parts, pressure monitoring parts, pipeline control card parts are arranged on the host platform surface, shaking table is arranged in the cabin of main frame inside, the gas-monitoring parts are arranged on the control panel of main frame top, and there are adjusting knob, button and display screen in the control panel surface, and there is computer control panel inside.
8. device according to claim 6, is characterized in that, the pump parts are power resources, adopts known technology and parts, and the running of pump changes pipeline inner pressure, for liquid drain or infusion provide power; The running of pump parts is set by control panel, and computer instruction is controlled.
9. device according to claim 6, is characterized in that, pressure monitoring device, gas controlling device are in pipeline traveling path, and be connected with it, during trigger alarm, computer automatic command control system, making pump and pipe controller make action, is the vitals that guarantees security of system.
10. device according to claim 6, it is characterized in that, control panel by display unit, set to regulate parts and computer processor forms, display unit can display device operation information and warning message, regulate button by setting, can setting device mode of operation and parameter; Computer processor is according to program prepared in advance operation according to flow control device.
11. device according to claim 6 is characterized in that, shaking table adopts known technology and parts, provides power by the machinery of bottom, constantly tilts to wave, and makes the blood in the blood storage bag of horizontal on it be in flow regime.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210396281.8A CN103170024B (en) | 2012-10-18 | 2012-10-18 | Normovolemic dilution autoblood collection and reinfusion system, and normovolemic dilution autoblood collection and reinfusion device |
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| CN201210396281.8A CN103170024B (en) | 2012-10-18 | 2012-10-18 | Normovolemic dilution autoblood collection and reinfusion system, and normovolemic dilution autoblood collection and reinfusion device |
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| CN103170024A true CN103170024A (en) | 2013-06-26 |
| CN103170024B CN103170024B (en) | 2015-06-03 |
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