CN103447104B - Pipettor - Google Patents
Pipettor Download PDFInfo
- Publication number
- CN103447104B CN103447104B CN201310139484.3A CN201310139484A CN103447104B CN 103447104 B CN103447104 B CN 103447104B CN 201310139484 A CN201310139484 A CN 201310139484A CN 103447104 B CN103447104 B CN 103447104B
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- China
- Prior art keywords
- dismounting
- spring
- backstop
- disconnected
- pipettor
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
- B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/023—Adapting objects or devices to another adapted for different sizes of tubes, tips or container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
Abstract
The present invention relates to a kind of pipettor, it has :-comprising the pressure unit of shaft-like outer casing underpart part, this pressure unit has: with the pressure chamber of limiting mechanism; The contact element being connected with limiting mechanism; The driver element of-driving limiting mechanism; Drive unit; With the coefficient executive component of drive unit and with the coefficient driving element of drive unit;-releasably the device of connection;-provision for disengagement, this provision for disengagement has dismounting guiding valve; Provision for disengagement also has dismounting extension;-terminal backstop and terminal stop element;-disconnected coupling device between drive unit and driving element; With-the bottom backstop that can be coupled with drive unit, the operative end that this bottom backstop is encountered dismounting extension at driving element and drive unit during by the disconnected connection of described disconnected coupling device, so that in the time that described executive component continues to move along direction of operating, dismounting extension makes to dismantle guiding valve and moves down.
Description
Technical field
The present invention relates to a kind of pipettor, this pipettor band is useful on the provision for disengagement at pipettor tip.
Background technology
Pipettor especially in laboratory for the dosage of liquid. For this reason, pipettor tip is clipped in and moves liquid with upper openingOn the running-on of device. Liquid is drawn and is discharged at pipettor tip by lower openings. Air-cushion type pipettor comprises the pressure for airArranging device, this clamping device is connected with pipettor tip communicatively by running-on. Make air-cushion moving by described clamping device, fromAnd liquid is sucked, pipettor is most advanced and sophisticated also therefrom discharges. Described clamping device is in most cases with therein movablyThe cylinder of piston.
Pipettor is most advanced and sophisticated with crossing afterwards from running-on disengagement and with changing at new pipettor tip. Can connect thusWhile getting off dosage, avoid polluting. The most advanced and sophisticated cost of disposable pipettor lowland can be used plastics.
For releasably keep the running-on at pipettor tip be about the taper of the shell of pipettor or cylindricality prominentGo out portion, pipettor tip can be clipped on this running-on with the upper opening mating with this running-on. This can not contact pipettor tip,By being pressed into be in the upper opening that keeps the pipettor tip in seat with running-on, pipettor just can complete.
For fear of pollution, known pipettor has the provision for disengagement with drive unit. By operation dismounting device button,Make to dismantle guiding valve by removal rod so mobile, that is, this dismounting guiding valve makes pipettor tip throw off from running-on, and user needn'tContact these pipettor tips. These pipettors have metering button for operating clamping device and for operation dismounting deviceIndependent stripping attachment button, thereby must operation two buttons.
Known a kind of Manual liquid transfering device with one push button operation device from DE2549477C3. This hand-driven moving liquidUtensil has shell, stretches out antagonistic spring effect and the executive component that can be pressed into from this shell upper, and this executive component is by promotingBar is connected with movable piston in cylinder. In the time of the described executive component of operation, piston is implemented adjustable driving stroke. ForRemaining liquid is discharged from pipettor tip, piston can be implemented super stroke. For this reason, at executive component and piston-gasBetween cylinder unit, have separable magnet arrangement unit, this magnet arrangement unit shows driving stroke by resistance to userFinish, overcome described resistance and implement afterwards super stroke. In addition, be provided with the dismounting stroke for dismantling pipettor tip. For this reason,Piston rod has stop element, and this stop element can make pulling off sleeves move in operative end, thereby this pulling off sleeves canWith dismounting end, pipettor tip is promoted from running-on at edge place thereon. By acting on the resistance of the spring on pulling off sleevesIndicate the beginning of dismounting stroke to user. In dismounting stroke procedure, piston moves together, therefore in cylinder, needs freedomSpace. This free space forms dead volume (Totvolumen), this dead volume infringement dosage precision.
DE19708151A1 has described the another kind of pipettor with one push button operation device, and this pipettor hasLittle dead volume. This pipettor has telecontrol equipment; Movable in cylinder by this telecontrol equipment, for mobile airPiston; For the fixing running-on at fixing pipettor tip, this fixing running-on has the opening being connected with cylinder; With when air courtThe opening of fixing running-on limits the backstop of piston movement while movement. This backstop is the end face of cylinder, when air is towards fixed coverDescribed in when the opening of mouth moves, piston is met this end face. In addition, this pipettor also has provision for disengagement, and this provision for disengagement has tears openWhen the section of unloading is moved for dismantling in provision for disengagement, pipettor tip is separated from fixing running-on; With lever piece for generation of tearing openUnload motion. In addition have disconnected coupling device, in the time arriving backstop, this disconnected coupling device makes piston and the disconnected connection of telecontrol equipment. Described disconnectedDevice by thering is the magnet arrangement cell formation of magnet and magnetizable counterpart, overcoming confining force after described magnet andDescribed counterpart is disconnected from each other. In the time of the disconnected connection of piston, the drivening piece being coupled with telecontrol equipment acts on lever piece, wherein, and bandMoving part forces provision for disengagement to dismantle motion by the motion of telecontrol equipment. In this pipettor, after driving strokeIf desired after the discharge stroke for discharging remaining liq by the motion of described backstop limited piston. Then, disconnected connectionDevice makes piston from the disconnected connection of telecontrol equipment. In the time continuing in the same direction operational movement device, piston does not continue motion, stillThe drivening piece motion being coupled mutually with described telecontrol equipment, this drivening piece acts on the lever piece of provision for disengagement and forces to carry outDismounting motion. Do not have the dismounting campaign of the continuation campaign of piston to reduce dead volume and improve dosage precision.
In known pipettor, piston is loaded in the time encountering cylinder distolateral, and therefore, piston must design enoughStable. In the physical dimension of the dosage volume for little, this wastes very much. When mounted, comprise disconnected coupling device and piston outsideTogether with shell upper-part must be screwed in the outer casing underpart part that comprises cylinder. When manufacture has the difference for different dosage scopesWhen the pipettor of physical dimension, shell upper part must be equipped different disconnected coupling device and cylinder, and then separately with correspondingOuter casing underpart part fit together.
DE102004003434B4 has described one and has comprised clamping device and be releasably connected with this clamping deviceThe pipettor of drive unit. Described clamping device have pressure chamber with limiting mechanism movably, for pipettor pointHold connected running-on and the interface channel between pressure chamber and the free end of running-on. For driving the removable of clamping deviceThe drive unit of limiting mechanism there is driving element, this driving element has and the work of throwing off of limiting mechanism movablyWith connecting (Wirkverbindung). Between described clamping device and described drive unit, have rotating connection of inserting, this is inserted and revolvesFormula connects can be by being formed on that driving element is connected to form with the effect between limiting mechanism movably and by taking offOpening driving element is connected and can throws off with the effect between limiting mechanism movably. This pipettor has for making pipettorMost advanced and sophisticated independent provision for disengagement of throwing off with running-on, this provision for disengagement has the dismounting being arranged on separately on drive unit and drives dressPut; Be arranged on stripping attachment on clamping device and between dismounting drive unit and provision for disengagement, along inserting rotating jockeyAxial grip jockey longitudinal axis orientation, that can throw off.
Summary of the invention
Set out thus, the object of the invention is to: a kind of pipettor is provided, and this pipettor reduces for different knots is providedThe expense of structure size and easy operating.
This object is achieved by the following pipettor of tool. The favourable project organization of this pipettor is in following contentIn provide.
Pipettor according to the present invention has:
-comprise the pressure unit of shaft-like outer casing underpart part, this pressure unit have set within it, with movingThe pressure chamber of moving limiting mechanism; With this movably limiting mechanism be connected, open at the upper case on shell lower component topThe contact element at mouth place; For at the most advanced and sophisticated running-on being connected of shell lower component bottom and pipettor with oneself of pressure chamber and running-onBy the interface channel between end;
-for driving the driver element of movably limiting mechanism of pressure unit, this driver element have shaft-like outsideShell upper-part; Be arranged on drive unit wherein; On described shell upper part, with the coefficient behaviour of described drive unitDo element and the lower case opening part of shell upper-part bottom, with the coefficient driving element of described drive unit,This driving element can move down by operating described executive component along direction of operating, to implement movably to limit machineThe dosage stroke of structure;
-for releasably connect device, these device in a construction unit by described shell upper part and instituteState outer casing underpart part and be releasably connected to each other to shaft-like shell, in described construction unit, the driving element contact element that reclinesPart;
-provision for disengagement, this provision for disengagement has the dismounting guiding valve being arranged on movably on outer casing underpart part, this dismountingGuiding valve has dismounting end for pipettor tip is thrown off from running-on in bottom, and in addition, described provision for disengagement also hasBe arranged on movably the dismounting extension on shell upper part, this dismounting extension is the upper end phase with dismounting guiding valve in bottomConnect;
-be arranged on terminal backstop in described shell upper part, that be fixedly connected with this shell upper part and drive with describedTerminal stop element that moving element is fixedly connected with, that move downward for limiting this driving element;
-disconnected coupling device between described drive unit and described driving element, this disconnected coupling device is at terminal stop elementThe terminal that reclines backstop and executive component continue while movement, driving element and drive unit to be broken along direction of operating and join; With
-bottom the backstop that can be coupled with drive unit, this bottom backstop at driving element and drive unit by disconnectedThe operative end of encountering dismounting extension when the disconnected connection of coupling device, to make dismounting in the time that executive component is mobile along direction of operating continuationExtension and dismounting guiding valve move down.
Pipettor according to the present invention has pressure unit and driver element, and this pressure unit and driver element are by taking offThe connection of opening and each other releasably connect. This connection that can throw off can be designed as inserts rotating connection, as at DE102004Described in 003434B4. In this respect with reference to DE102004003434B4 and US2005/155438A1, because ofThis, their content is also included in this application. Described pressure unit is arranged in outer casing underpart part. This pressure unit comprises pressureRow chamber and movably limiting mechanism. Preferably this pressure unit is cylinder and the piston that arranges movably therein. In assemblingWhen pressure unit and driver element, will piston or other movably limiting mechanism be installed in pressure unit. Work as shellWhen upper-part is connected with outer casing underpart part, the driver element contact element that reclines. The drive unit of driver element and movably limitBeing coupled by following manner of mechanism processed completes, that is, and and the contact element of the driving element contact pressure unit of driver element. Like thisContact can by between described pressure unit and driver element combination and form can throw off be connected and simply form.In addition, pipettor has terminal backstop, and the terminal stop element being fixedly connected with described driving element is encountered described terminal backstop,So that limiting described driving element moves down. Different from DE19708151A1, terminal backstop is not the lower end of cylinderFace. Or rather, this terminal backstop is arranged in shell upper part and with this shell upper part and is fixedly connected with, and described inDriving element has terminal stop element. Therefore, piston does not bear load owing to colliding in terminal backstop. Answering especiallyThis is applied in the driver element of pipettor series of the pipettor with different structure size without change, terminal backstop and endEnd stop element can so be constructed, that is, they sustain maximum expection power. Also can apply pressure unit, this pressure listUnit is designed in order to make piston encounter the end face of cylinder when the downward mobile end. In the time of incoming terminal backstop, pistonBe preferably placed at before the lower surface of cylinder not far local or be just positioned on the lower surface of this cylinder, to protect as small as possibleHold dead volume and keep as small as possible thus thing followed dosage error. In addition, described driver element is driving unitBetween part and driving mechanism, there is disconnected coupling device. In the time that executive component continues to move along direction of operating, when terminal stop element pastesDuring by terminal backstop, described disconnected coupling device makes driving element and the disconnected connection of drive unit. Therefore, drive unit as before along phaseSame direction continues motion. Drive unit is connected with bottom backstop, and this bottom backstop is at driving element and drive unitWhen disconnected connection, encounter the operative end of dismounting extension. Therefore, along direction of operating continuation is mobile, dismounting is prolonged by executive componentLength portion and dismantle in addition guiding valve move down together with this dismounting extension. Thus pipettor tip is pushed open from running-on. RootCan realize thus according to pipettor of the present invention that a unique executive component is controlled dosage and dismounting moves liquid by only operatingDevice tip. In the time that dismounting pipettor is most advanced and sophisticated, pressure chamber and movably limiting mechanism do not have adversely bearing load. AvoidLarge dead volume and the dosage error thereupon occurring. The basic structure that comprises the pipettor of pressure unit and driver element makes peaceInstallation and dismantling are unloaded and are become simple. In addition can apply described pressure unit and driver element, to assemble different pipettor types.Can adopt especially pressure unit-these pressure unit with driver element is not to be designed to for only by one at firstIndividual executive component is implemented control to dosage process and unloading process-to be configured for the pipettor of one push button operation. ThisSame driver element can be fitted together from different pressure unit outward, so that formation has different dosage scopesPipettor.
By direct or indirect mechanical connection, executive component and drive unit acting in conjunction. By direct or indirectMechanical connection, driving element and drive unit acting in conjunction. The preferred linearity of the direction of operating ground of executive component extends. This operationPreferably extending longitudinally along shaft-like shell of direction. Alternatively, direction of operating and described be longitudinally angle (for example 45 ° or90 °) extend. The scheme alternative according to other, direction of operating for example, along bending curve, extend on rail at circle. At straight lineIn the situation of the direction of operating of property, preferably button of executive component, and in the case of bending direction of operating, executive component is excellentChoosing is pivotable lever.
According to the preferred project organization of one, pressure unit is cylinder and piston movably therein. Alternatively, pressRow unit be pressure chamber with and interior movably flexible wall or diaphragm.
According to the preferred project organization of one, drive unit is lifting arm. According to another kind of project organization, lifting arm is postShape lifting arm. According to another kind of project organization, lifting arm is by metal or be made of plastics.
According to the preferred project organization of one, contact element is in the piston plate of the upper end of piston or upper with pistonThe piston plate of the upper end of the connected piston rod in end. This piston plate preferred water level land orientation. According to a kind of alternative design knotStructure, contact element is the upper end of the upper end of piston or the piston rod that is connected with piston.
According to the preferred project organization of one, bottom backstop is that the effect of the super stroke spring of opposing movably stops downwardsBlock body, in the time that a dosage stroke finishes, the stop element of drive unit is encountered described backstop. When driving element continues downwardsWhen mobile, implement super stroke, and described backstop is resisted the effect of super stroke spring and moves down. In the time moving down,Bottom backstop encounter dismounting extension and by this dismounting extension along direction of operating to pressing down.
According to a kind of project organization, pipettor is Manual liquid transfering device, that is, user can only keep with a hand in the time moving liquidAnd manipulation.
According to another kind of project organization, drive unit has stop element and top backstop and bottom backstop, backstopElement is removable between described top backstop and described bottom backstop, to implement dosage stroke, wherein, bottom backstopBody by super stroke spring supporting in shell upper-part so that after enforcement dosage stroke by executive component along operationThe continuation of direction is moved the elastic force of the super stroke spring of opposing until incoming terminal backstop and implement super punching by terminal stop elementJourney. In dosage stroke, stop element moves between top backstop and bottom backstop, wherein, this stop element forLiquid is sucked to be sleeved on pipettor on running-on most advanced and sophisticated and move from bottom backstop to top backstop and for by skyGas or liquid move to bottom backstop from top backstop from most advanced and sophisticated discharge of pipettor. User feels stop elementCollision, this is because bottom backstop passes through super stroke spring supporting in shell upper-part. In the time of imbitition, ensure thusAccurately implement the dosage stroke of expection. In the time discharging liquid, user can implement super stroke extraly, so that raffinateBody is discharged from pipettor is most advanced and sophisticated. By apply the power of raising on executive component, user can overcome the bullet of super stroke springPower also surpasses stroke, until driving element stops by terminal backstop. After surpassing stroke, user can with retouchedThe mode of stating is controlled the dismounting at pipettor tip as follows, that is, he makes disconnected multi pack by apply corresponding power on operating mechanismPut disconnected connection.
When super stroke finishes or executive component start to continue when mobile along direction of operating, bottom backstop is with its outward flangeBe placed in the operative end of dismounting extension, move down to make to dismantle extension as drivening piece. Thus, bottom backstopBody has been realized the function of restriction dosage stroke with favourable and the mode that reduces construction expenditure, that is, can realize super stroke andControl the dismounting at pipettor tip. In addition, this project organization can be realized: dismounting extension can be from side guiding through superStroke device, driving element and disconnected coupling device. In addition, thus also under super stroke device for dismounting spring provide space forMake provision for disengagement be returned to initial position, in this initial position, pipettor tip can be overlapped and install on running-on.
According to another kind of project organization, top backstop is removable in shell upper-part, and this shell upper part toolThere is the adjusting device being coupled mutually with top backstop for regulating position and definite dosage stroke of top backstop. By describedThe adjustable amount of liquid that needs dosage of adjusting device. According to another kind of project organization, top backstop is leading screw, on this leading screw hasThe passage of portion, the lifting arm guiding of drive unit is through the passage on described top. Described leading screw is being arranged on by adjusting deviceIn feed screw nut in shell upper part and that be fixedly connected with this shell upper part, can reverse and can move axially thus.The backstop for stop element is served as in the lower surface of described leading screw. The position of described lower surface is conclusive to dosage stroke.
According to a kind of project organization, stop element is the flange on lifting arm periphery, and lifting arm extends throughThe passage of the bottom of the passage on the top of portion's backstop and bottom backstop, and described flange be arranged on top backstop with underBetween portion's backstop.
According to another kind of project organization, disconnected coupling device has two disconnected connection elements, and one of them breaks and joins element and drive dressPut and be connected and another disconnected connection element is connected with driving element, wherein, these break and join elements on a definite link positionReleasably combination, and can away from each other and can be moved back in holding position after overcoming definite confining force. DisconnectedCoupling device can be incorporated between drive unit and driving element simply. When being applied to disconnected multi pack by operating operation elementWhen the power being set up exceedes confining force, disconnected coupling device is disconnected connection. Thus in the time that liquid finishes from the discharge at pipettor tip, userFeel resistance. This can make user easily first pipettor be aimed to container, to implement dosage, and then will moveLiquid device is aimed at for the waste material container at pipettor tip, to dismantle pipettor tip with the operating physical force improving. Confining force is preferredBe 25 newton to the maximum, be preferably in addition 22 newton to the maximum. The preferred minimum of confining force is 10 newton, and preferably minimum is 16 newton. ExcellentSelecting confining force is 19 newton.
According to a kind of project organization, each disconnected element comprise two magnet or magnet and ferromagnetic counterpart and/Or pawl device and/or spring assembly, described device releasably remains on each disconnected element in link position. Preferably,Disconnected connection element has magnet arrangement unit, and this magnet arrangement unit comprises two magnet or a magnet and a ferromagnetic cooperationPart. Magnet is permanent magnet preferably.
Described disconnected coupling device especially can be as constructed described at DE19708151A. Reference in this respectDE19708151A, therefore its content includes in this application.
According to another kind of project organization, driving element is sleeve, and its bottom is placed on contact element; Disconnected coupling device bagDraw together the disconnected connection of top disconnected connection element and the bottom element of the through hole with top, described top disconnected connection element be arranged in sleeve andBe fixedly connected with this sleeve, described bottom disconnected connection element is arranged on movably in sleeve and is fixed on the bottom of lifting armUpper, this lifting arm extends into sleeve and the through hole through described top from top; And sleeve extends through terminal backstopAnother through hole and there is another flange radially outward stretching out, this another flange is by being placed in terminal backstopOn upside, limiting driving element moves downward. In this project organization, disconnected coupling device is saved to be integrated in spatially and is driven unitIn part. Disconnected coupling device can be arranged on the lifting arm of drive unit by driving element. Terminal stop element passes through simplyAnother flange of sleeve is realized.
According to another kind of project organization, in sleeve, under the disconnected connection element of bottom, be provided with disconnected connection spring, disconnected connection elementBy described disconnected spring supporting in sleeve. After executive component unloads, the connection spring that breaks breaks bottom disconnected connection element to join to topElement pushes back, to this disconnected connection component tape is got back to link position.
According to another kind of project organization, sleeve has lower sleeve portion section and upper sleeve section, wherein, and described lower sleeve portion sectionThe diameter having is less than the diameter of described upper sleeve section, and this lower sleeve portion section extends through the upper case of outer casing underpart partOpening and being placed on contact element with its bottom, and disconnected connection element is arranged in upper sleeve section. Thus for settlingDisconnected connection element provides enough structure spaces and can realize sleeve the upper case with minor diameter that stretches into clamping deviceOpening.
According to another kind of project organization, the super stroke spring that super stroke spring is supported on annular in shell upper-part props upOn bearing apparatus; Sleeve steering is by the through hole of super stroke supporting device of the spring; And super stroke supporting device of the spring is for coverThe terminal backstop of the flange of cylinder. Thus the function with terminal backstop of super stroke supporting device of the spring is combined and fallenLow construction expenditure.
According to another kind of project organization, dismounting extension by being arranged on super stroke spring-loaded dress in shell upper-partDismounting spring under putting and being supported in shell upper part.
According to another kind of project organization, dismounting spring is being dismantled the super stroke spring that is arranged on extension in upper supportOn top under supporting arrangement dismounting supporting device of the spring and be fixed together with shell in lower support(gehaeusefest) on bottom dismounting supporting device of the spring.
According to another kind of project organization, dismounting guiding valve is pulling off sleeves, and this pulling off sleeves is by all at outer casing underpart in itOn part, guide. The sleeved form of pulling off sleeves tool. According to another kind of project organization, dismounting extension has multiple parallelBar, these bars are connected with each other by the top dismounting supporting device of the spring of annular in the certain distance of dismounting guiding valve.Dismounting slide-valve design becomes sleeve to realize to be easily arranged on pressure unit. If desired, can in order to clean, to safeguard or keeping in repairDismantle simply and install described dismounting guiding valve. Being designed with of multiple parallel bars that have of dismounting extension is beneficial to saving spaceGround guides in shell upper-part. Each bar is fixed on upper area and is prevented by the dismounting supporting device of the spring of annularUnexpectedly from shell upper part, pull out.
According to another kind of project organization, dismounting guiding valve is connected by least one buckle and interconnection mutually with dismounting extensionConnect. Buckle connection makes to dismantle guiding valve and the installation of dismounting extension and dismounting if desired and becomes simple.
According to another kind of project organization, dismounting extension be connected with stripping ring by the first buckle connecting device and described in tear openUnloading ring is connected with dismounting guiding valve by the second buckle connecting device. This be conducive to anti-lost lost territory will dismantle from top extension andBe arranged on shell upper part from below by dismounting guiding valve; Be conducive to dividually dismounting guiding valve is arranged on to outer casing underpart part with itAbove be connected with outer casing underpart part with by shell upper part and stripping ring be connected with dismounting guiding valve simultaneously.
According to another kind of project organization, super stroke spring and/or disconnected connection spring and/or piston spring and/or dismounting springHelical spring and/or volute spring. Helical spring or volute spring can advantageously be placed in shaft-like shell andSuitable spring hardness can be provided.
Brief description of the drawings
Further set forth the present invention by the accompanying drawing of embodiment below. In accompanying drawing:
Fig. 1 is according to the longitudinal section of pipettor of the present invention;
The longitudinal section of the amplification on the top of the same pipettor of Fig. 2;
Fig. 3 is along the cutaway view of the amplification of III-III line in Fig. 2;
The details of the amplification of the IV of Fig. 4 Fig. 2;
The longitudinal section of the amplification of the bottom of the same pipettor of Fig. 5;
The longitudinal section of the amplification of the bottom of the same pipettor of Fig. 6 in the situation that there is no lifting body;
Fig. 7 a-d illustrate respectively same pipettor before operating operation element (Fig. 7 a), implement dosage fullyAfter stroke and before implementing super stroke (Fig. 7 b), implement super stroke afterwards and before dismantling pipettor tip, (Fig. 7 c) and tear openThe part longitudinal section of (7d) after unloading pipettor tip;
Fig. 8 according to pipettor of the present invention (dotted line) and traditional pipettor (solid line) at dosage stroke, super stroke with tear openPower-displacement diagram while unloading stroke.
Detailed description of the invention
In this application, "up" and "down", " ... on " and " ... under " and the saying of " level " and " vertical "Bright is the orientation in the time that shell is directed with running-on verticallydownwardly about pipettor. In this orientation, be placed in moving on running-onThe container being positioned under this pipettor tip can be aimed in liquid device tip, to draw or discharge liquid.
According to Fig. 1 and 2, pipettor 1 has shell 1 shaft-like, that be shaped to handle, and this shell has shell upper part 2With outer casing underpart part 3. Shell upper part 2 and whole contained parts form driver element, and outer casing underpart part 3 and all containedParts form pressure unit. The executive component 4 of the button form of cylindricality stretches out from shell upper part 2 on top. OperandPart 4 is axially movable and can be rotated to support in shell upper part 2.
Executive component 4 is fixedly screwed on the lifting arm 6 of cylindricality with the screw thread in cover plate 5. Lifting arm 6 is at shell upper-partIn 2, pass the passage 7 on the top of leading screw 8. Leading screw 8 screws in the internal thread of feed screw nut 9, and this feed screw nut is at shell upper-part 2In remain on the position of restriction.
Feed screw nut 9 is fixedly connected with the lifting body 10 being fixed in shell upper part 2. Lifting body 10 is cylindricality substantiallyAnd for feed screw nut 9, screw in this feed screw nut lifting arm 6 leading screw 8 and that guide at this leading screwSupport body. Installing when pipettor, by these and other member pre-installation on lifting body 10 and will be equipped with these membersLifting body 10 be arranged in shell upper part 2, this lifting body is remained in shell upper part 2 regularly. For this reason, promoteBody 10 and shell upper part 2 kaysers. Also pre-installation can be directly installed on shell by the member on lifting body 10 in principleIn parts 2. For this reason, can be configured the inside of shell upper 2 according to lifting body 10.
Leading screw 8 has on top and its leading screw drivening piece 11 that (drehfest) is connected not in relative rotation. This leading screw bandMoving part 11 has the hexagon 12 with centre bore 13 on periphery. This hexagon 12 is rabbeted the interior hexagon 14 at executive component 4In.
Executive component 4 is provided with two radially protuberances 15,16 of diametrically contraposition each other in bottom, these radially protuberance toOuter outstanding. Preferably have 4 radially protuberances 15,16. These radially protuberance 15,16 be scarfed to the transferring elements in hollow cylindricalIn axially extended groove 17,18 on 19 inner side, described transferring elements can be rotated to support in shell upper part 2. TransmitParts 19 have ring gear 20 in periphery on top, this ring gear is meshed with the gear of counter transmission device 21, and this counter passesMultiple counter wheels 22 that are arranged side by side on a horizontal axis of moving device actuation counter 23. Described counter 23 is fixingOn shell upper-part. Each counter wheel 22 has respectively numeral 0 to 9. About Fig. 1 in the end the counter wheel 22 on limit by countingDevice transmission device 21 drives. In the time being arranged on the counter wheel of back and being transitioned into 0 from 9, be arranged on counter wheel 22 phases on sideAnswer and be further rotated a numeral.
On counter 23, shell upper part 2 has the cover plate of outer casing 24 with form, can read meter through described formThe numeral of number device wheel 22.
Under leading screw 8, on lifting arm 6, be provided with the flange 25 of protuberance form as stop element. Lifting arm 6 toOn the recline lower end side 26 of leading screw 8 of flange 25 that moves through limited, the top that this lower end side is configured for flange 25 is onlyBlock body.
Under feed screw nut 9, in lifting body 10, be provided with the bottom backstop 27 of plate-like substantially. This bottom backstopBody 27 has the recess of cup-shaped, is provided with the passage 28 of bottom at the center of this recess. In addition, bottom backstop 27 has threeThe protuberance 29 radially outward stretching out, these protuberances are evenly distributed on the periphery of this bottom backstop.
Described bottom backstop 27 is guiding in axially extended each guide slit 30 of lifting body 10 on each protuberance 29,This is also shown in Figure 3. Can the move up upper end of until each protuberance 29 reclines each guide slit 30 of described bottom backstopPortion.
Under bottom backstop 27, in lifting body 10, be provided with and be configured to helical spring super stroke spring 31. ShouldRecline on the top downside of described bottom backstop 27 of super stroke spring. Described super stroke spring 31 is being arranged in lower supportOn super stroke supporting device of the spring 32 wherein and that be fixedly connected with it.
Super stroke supporting device of the spring 32 is made up of the ring with L shaped cross section, and wherein, the horizontal flange of L shaped profile is lived(umrandet) central through hole 33 of super stroke supporting device of the spring 32. Super stroke spring 31 is supported on the horizontal sides of L shaped profileGo up and surrounded by vertical edge at side. Super stroke spring 31 makes bottom backstop 27 press to each protuberance 29 by pretightning forceThe upper end of each guide slit 30.
Under bottom backstop 27, in lifting body 10, there is the driving with the coaxial directed form of sleeve of lifting arm 6Element 34. This driving element 34 has upper sleeve section 35 and lower sleeve portion section 36, and wherein, 35 of described upper sleeve sections haveInternal diameter and external diameter be greater than internal diameter and the external diameter of described lower sleeve portion section 36. Described lower sleeve portion section 36 has truncated cone shape in bottomTip 37.
The upper edge of upper sleeve section 35 have radially outward stretch out, around other flange 38. Top coverThe external diameter of cylinder section 35 is less than the internal diameter of the through hole 33 of super stroke supporting device of the spring 32, therefore, and upper sleeve section 35 and bottom coverCylinder section 36 can be inserted in through hole 33. The external diameter of described other flange 38 exceedes the internal diameter of through hole 33, therefore, and driving element 34Can not pass completely through through hole 33. Super stroke supporting device of the spring 32 forms terminal backstop and other flange 38 forms terminal backstopElement, their restriction driving elements 34 move down.
In upper sleeve section 35, be provided with the armature 39 of the hollow cylindrical being formed by ferromagnetic material on top. In this rankUnder iron, in upper sleeve section 35, be provided with the magnet 40 of hollow cylindrical. It under this magnet, is the tank that holds this magnet 40Shape device 41. Described armature 39 has pressing base in upper sleeve section 35. Lifting arm 6 extend through movably armature 39 inHeart hole. Under armature, lifting arm 6 has the aciculiform section 42 that diameter reduces. Magnet 40 and tank shape device 41 are placed in aciculiform sectionOn 42. Preferably, magnet 40 and tank shape device 41 are fixed in aciculiform section 42, for example, have there pressing base by themRealize. In addition, magnet 40 is in upper support on the boss at lifting arm, and aciculiform section 44 is from this boss.
Under annular disk 41, be configured to helical spring disconnected spring 43 and guide in aciculiform section 42, described disconnected bulletSpring is in lower support on the bottom 43 in lower sleeve portion section 36. Armature 39, magnet 40 and disconnected connection spring 43 are disconnected coupling devices 44Member.
According to Fig. 1,2,5 and 6, shell upper part 2 is gone back except being provided with on interior week lower case opening 45 in bottomBe provided with further do not set forth, for releasably connecting with the other device for being releasably connected of outer casing underpart part 3The device 46 connecing.
Outer casing underpart part 3 has hollow cylindrical section 47 on top, be connected with in the bottom of this hollow cylindrical section shorter, haveThe top conical hollow section 48 of large cone angle, be connected with again in the bottom of this top conical hollow section long, there is small-angleLower hollow conical section 49, the running-on 50 that this lower hollow conical section forms taper with its bottom is for clamping pipettor tip51. Clamped pipettor tip 51 is equally substantially tapered, and it has upper shed 52, and for cover, to install to running-on 50 upper and lowerOpening 53 is for passing through liquid. Upper shed 52 is greater than under shed 53 substantially, and pipettor tip 51 is downward from upper shedOpening is tapered.
The hollow cylindrical section 47 of outer casing underpart part 3 be provided with in periphery on top further do not set forth, for throwing offThe other device 54 that ground connects, device 46 phases for being releasably connected of these other devices and shell upper part 2Coupling, to be releasably connected shell upper part 2 with outer casing underpart part 3. In DE102004003434B4, describeThe suitable device 46,54 for shell upper part 2 is releasably connected with outer casing underpart part 3. Reference in this respectDE102004003434B4 and US2005/155438A1, therefore their content is included in this application.
Lower hollow conical section 49 has the convex shoulder that stretches out top conical hollow section 48 in shell lower component 3 on top55。
Lower hollow conical section 49 has interface channel 56, and this interface channel is by under the upper surface of convex shoulder 55 and running-on 50End face is connected.
In shell lower component 3, be provided with and comprise cylinder 57 and the structure list of piston 58 movably in this cylinderUnit. Described cylinder 57 is with lower area insertion interface channel 56 and by pushing or being adhesively fixed therein. In bottom, cylinder57 seal by O shape ring 59 relative interface channels 56.
Piston 58 has piston seal 60 on periphery, and this piston seal is at inner sealing cylinder 57. Close at pistonUnder sealing 60, piston 58 has aciculiform convex shoulder 61, and this aciculiform convex shoulder can insert the through hole 62 in cylinder 57 bottoms and can insertEnter interface channel 56, to reduce dead volume. Cylinder 57 and piston 58 are vertically-oriented. On top, piston 58 support levels are fixedTo piston plate 63, this piston plate has vertically-oriented tapered recess 64 for holding the tip of driving mechanism 34 at center37。
Outer casing underpart part 3 has tank shape seal bootr 65 on top, this tank shape seal bootr has shell face cylindricality or taper.The bottom of seal bootr 65 is arranged on piston plate 63 and has the upper case opening 67 at center, opens by this upper caseMouth can be from top contact piston dish 63. Seal bootr 65 has outwardly directed protuberance 68 on the edge of its shell face, theseProtuberance is buckled in the corresponding recess 69 of hollow cylindrical section 47 of outer casing underpart part 3.
The bottom limited piston 58 of seal bootr 65 moves up. Be configured to helical spring, lower support on convex shoulder 55And the piston spring 70 of upper support on the downside of piston plate 63 by piston 58 the downside pretension towards seal bootr 65.
In addition, pipettor 1 also has provision for disengagement 71. This provision for disengagement 71 comprises and is arranged on tearing open on outer casing underpart part 3Unload guiding valve 72. This dismounting guiding valve 72 have with hollow cylindrical section 47, top conical hollow section 48 with lower hollow conical sectionThe profile that 48 profile matches. Described dismounting guiding valve has the dismounting end 73 of annular in bottom. This dismounting end 73 existsThe position of the dismounting guiding valve 72 shown in Fig. 1 is upwards shifted onto on outer casing underpart part 3 as far as possible far, makes for being set with pipettorMost advanced and sophisticated 51 running-on 50 exposes.
Dismounting guiding valve 72 is connected with dismounting extension 74 on top. This dismounting extension comprises three vertical removal rods75, these removal rods are connected with the top edge of dismounting guiding valve 72. Each removal rod 75 is evenly distributed in the top of dismounting guiding valve 72On edge. Each removal rod 75 is connected with stripping ring 76 by the first buckle connecting device in bottom, and this stripping ring is by the second buckleJockey is connected with the top edge of dismounting guiding valve 72. Each removal rod 75 on top in the certain distance of stripping ring 76,Their interior week above interconnects by annular top dismounting supporting device of the spring 77. Described top dismounting supporting device of the spring77 have L shaped cross section, and wherein, the through hole 33 under the horizontal sides of described cross section and super stroke supporting device of the spring 32 adjoinsAdjacent. The vertical circumferential edge of top dismounting supporting device of the spring 77 is pointed to below.
Each removal rod 75 has operative end 78 on top.
Dismounting extension 74 or removal rod 75 extend into shell upper part 2 through lower case opening 45. Dismounting is prolongedLength portion 74 the recline downside of super stroke supporting device of the spring 32 of top dismounting supporting device of the spring 77 that moves through is upwards able toRestriction.
Under top dismounting supporting device of the spring 77, stretch out three contact pin 79 from the inner side of shell upper part 2, they are equalThe even space that distributes and be arranged on interior week above and pass (durchgreifen) lifting body 10. This is shown in Figure 4 especially. RespectivelyContact pin 79 forms bottom dismounting supporting device of the spring 80. Being configured to helical spring dismounting spring 81 is arranged on by pretightning forcePortion's dismounting supporting device of the spring 77 and bottom are dismantled between supporting device of the spring 80 and provision for disengagement 71 are upwards pushed, and makeThe top dismounting supporting device of the spring 77 super stroke supporting device of the spring 32 that reclines.
Outer casing underpart part 3 is directed to the lower case opening 45 of shell upper part 2 with the upper area of hollow cylindrical section 47In. Releasably connect each other for the device 46,54 that shell upper part 2 is releasably connected with outer casing underpart part 3.Driving mechanism 34 is scarfed to most advanced and sophisticated 37 the piston plate 63 that reclines in upper case opening 67 and in recess 64. This piston plate 63Described driving mechanism 34 is upwards pushed, and by disconnected coupling device 44, lifting arm 6 is pushed with flange to leading screw 8.
Can use as follows pipettor 1:
This pipettor is grabbed on shell upper-part 2. Regulate dosage stroke by rotation executive component 4, until countingDevice wheel 22 shows desired dosage volume. In rotation when executive component 4, leading screw 8 is rotated by leading screw drivening piece 10 andThis leading screw is owing to moving axially with being threaded of feed screw nut 9 being fixed in shell upper part 2. At this, leading screw drivesPart 10 slips into the interior hexagon of executive component 4. Meanwhile, by other radially protuberance 15,16, transferring elements 19 is rotated alsoAnd adjust counter 23. Therefore, can read leading screw 8 in shell upper-part 2 on the axial location sum counter 23 through overregulatingDosage volume.
In addition, pipettor tip 51 is clipped on running-on 50, preferably keep in seat by this running-on being pressed into remain onIn pipettor tip 51, be achieved.
Before imbitition by air from cylinder 57 in the following manner discharge, that is, and by executive component 4 to pressing downPiston 58, until other flange 38 is encountered bottom backstop 27. At this, lifting arm 6 makes driving element by disconnected coupling device 4434 move downward, and piston 58 is deeper pressed into cylinder 57. At this, due to the power between magnet 40 and armature 39, disconnected connectionDevice 44 is connection constantly.
Then, the bottom at pipettor tip 51 by pipettor 1 slip into liquid and by releasing operation element 4 incite somebody to actionThe amount of expecting sucks pipettor tip 51. At this, piston spring 70 is by piston 58 and thus by driving element 34 and liftingBar 6 pushes back initial position, at the leading screw 8 that reclines of flange 25 described in this initial position.
Fig. 1,2,5,6 and 7a show be exactly that pipettor 1 is in said circumstances.
Afterwards, make pipettor tip 51 point to other container with bottom by pipettor 1. By downward press operation element4 move downward lifting arm 6 and by disconnected coupling device 44, driving element 34 are moved down, and make piston 58 again at cylinderIn 57, move downward. At this, substantially discharge the dosage regulating. Fig. 7 b illustrates this situation.
Can in the following manner the residue remaining in pipettor tip 51 be discharged, that is, disappear by the power improvingConsumption continues downward press operation element 4.
At this, bottom backstop 27 is resisted the effect of super stroke spring 31 and in guide slit 30, is moved down and pass throughDisconnected coupling device 44 makes driving element 34 continue to move down, and piston 58 is deeper pushed cylinder 57 by this driving element. In super punchingIn journey process, generate another over pressure, this over pressure squeezes out the liquid sticking on the inwall at pipettor tip 51.
In the time that driving element 34 encounters with other flange 38 the super stroke supporting device of the spring 32 that forms terminal backstop, superStroke finishes. Meanwhile, each protuberance 29 arrives the operative end 78 of dismounting extension 74 or is located thereon with small distance,Fig. 7 C illustrates this situation.
Can dismantle afterwards pipettor tip 51. For this reason, continue downward press operation element 4 with the power consumption improving. Super punchingJourney supporting device of the spring 32 stops described driving element 34 to continue to move downward. Make magnet 40 de-with armature 39 by the power improvingOpen, and lifting arm 6 continues to move downward and drives bottom backstop 27. Bottom backstop 27 is operating with each protuberance 29The extension 74 of extruding dismounting downwards on end 78. Dismounting extension 74 drives dismounting guiding valve 72 downward together, described dismounting guiding valveWith dismounting end 73, pipettor tip 51 is pressed from running-on 50.
During dismounting stroke, piston 58 does not continue to move downward in cylinder 57. Therefore, in cylinder 57 in bottom notThe bottom that needs dead volume and piston 58 not to encounter cylinder 57. If magnet 40 is thrown off with armature 39, for executive component 4The power consumption that continues to move down reduces again. In the time that dismounting extension 74 is encountered the unshowned dismounting backstop in shell, tear openUnloading stroke finishes. Fig. 7 d illustrates this situation.
After releasing operation element 4, pipettor 1 automatically get back to Fig. 1,2,5,6 and 7a shown in initial position. At this, tear openUnloading spring 81 upwards pushes dismounting extension 74 and upwards pushes thus dismounting guiding valve 72. In addition, disconnected connection spring 43 upwards squeezesPress lifting arm 6 and magnet 40, until magnet 40 is fixed on armature 39 by magnetic force. In addition, super stroke spring 31 upwards squeezesDepress portion's backstop 27, until each protuberance 29 arrives the upper end of each guide slit 30. In addition upwards extrusion piston of piston spring,58, driving element 34 and upwards push lifting arm 6, the leading screw 8 until flange 25 reclines by disconnected coupling device 44.
Described shell upper part 2 can be connected with other outer casing underpart part 3 simply, in this outer casing underpart part, and gasCylinder 57 and piston 58 have different cross sections. Correspondingly, same shell upper part 2 can be for the manufacture of having different dosagesThe pipettor 1 of volume. In addition likely: in the situation that breaking down, shell upper part 2 or outer casing underpart part 3 are easily moreChange or necessary situation under be other outer casing underpart part 3 of shell upper part 2 equipment. In addition, for maintenance, repair and clean, energyEnough easily outer casing underpart part 3 is taken off from shell upper part 2.
According to Fig. 8, in pipettor 1 according to the present invention, the operating physical force applying in the time implementing dosage stroke is only faintGround rises. Dosage stroke finishes after the operation displacement of about 14 millimeters.
For super stroke subsequently, first must significantly improve the power being applied on executive component 4, about 3 newtonBe raised to about 10.5 newton. Afterwards, for super stroke need apply the operating physical force of rising, this operating physical force ratio is used for implementing dosage strokeOperating physical force ascensional range larger. Super stroke finishes after the operation displacement of about 17 millimeters.
For dismounting stroke subsequently, must apply about 19 newton's disposable dismounting power. Afterwards, in order to dismantleThe power applying roughly raises along the extendible portion of the straight line for super stroke.
According in a kind of traditional pipettor of DE2549477C3, for dosage stroke need be applied to the water of risingPower on flat. At the peak value that occurs a power in the time that dosage stroke is transitioned into super stroke. Equally, in order to remove magnet, to tearing openWhile unloading stroke transition, also needing jumping characteristic raises power. The operating physical force that need apply in when dismounting rise to higher level andThan in pipettor according to the present invention sharply.
Reference numeral table
1 pipettor
2 shell upper parts
3 outer casing underpart parts
4 executive components
The cover plate of 5 operating mechanisms
6 cylindricality lifting arms
The passage on 7 tops
8 leading screws
9 feed screw nuts
10 lifting bodies
11 leading screw drivening pieces
12 hexagons
13 holes
14 interior hexagons
15,16 protuberances radially
17,18 grooves
19 transferring elements
20 ring gears
21 counter transmission devices
22 counter wheels
23 counters
24 cover plate of outer casing
The flange of 25 protuberance forms
26 lower end side
27 bottom backstops
The passage of 28 bottoms
29 protuberances
30 guide slit
31 surpass stroke spring
32 surpass stroke supporting device of the spring
33 through holes
34 driving elements
35 upper sleeve sections
36 lower sleeve portion sections
The tip of 37 truncated cone shapes
38 other flanges
The armature of 39 hollow cylindrical
The magnet of 40 hollow cylindrical
41 tank shape devices
42 aciculiform sections
43 disconnected connection springs
44 disconnected coupling devices
45 lower case openings
46 for releasably connect device
47 hollow cylindrical sections
48 top conical hollow sections
49 lower hollow conical sections
The running-on of 50 tapers
51 pipettor tips
52 upper openings
53 lower openings
54 for releasably connect other device
56 interface channels
57 cylinders
58 pistons
59O shape ring
60 piston seals
61 aciculiform convex shoulders
62 through holes
63 piston plates
64 tapered recess
65 tank shape seal bootrs
67 upper case openings
68 protuberances
69 recesses
70 piston springs
71 provisions for disengagement
72 dismounting guiding valves
73 dismounting ends
74 dismounting extensions
75 removal rods
76 stripping rings
77 top dismounting supporting device of the spring
78 operative end
79 contact pin
80 bottom dismounting supporting device of the spring
81 dismounting springs
Claims (18)
1. pipettor, it has:
-comprise the pressure unit of shaft-like outer casing underpart part (3), this pressure unit has: set within it, be with removableThe pressure chamber (57) of limiting mechanism (58); Be connected with described movably limiting mechanism (58), at described outer casing underpart part(3) contact element (63) that the upper case opening (67) on top is located; For with described outer casing underpart part (3) bottom with move liquidThe running-on (50) that device tip (51) is connected and being connected between described pressure chamber (57) and the free end of described running-on (50)Passage (56);
-drive the driving of the movably limiting mechanism (58) of described pressure unit for shell upper part (2) shaft-likeUnit; Be arranged on the drive unit in this driver element; On described shell upper part (2), with described drive unit commonThe executive component (4) of effect and locate at the lower case opening (45) of described shell upper part (2) bottom, with described driving dressPut coefficient driving element (34), this driving element can by operate described executive component (4) along direction of operatingMove down, so that the dosage stroke of limiting mechanism (58) movably described in implementing;
-for releasably connect device (46,54), these device in a construction unit by described shell upper part(2) and described outer casing underpart part (3) be releasably connected to each other to shaft-like shell, in described construction unit, described drivingElement (34) the described contact element (63) that reclines;
-provision for disengagement (71), this provision for disengagement has the dismounting guiding valve being arranged on movably on described outer casing underpart part (3)(72), this dismounting guiding valve has dismounting end (73) for pipettor tip (1) is thrown off from described running-on (50) in bottom;And in addition, described provision for disengagement (71) also has the dismounting extension being arranged on movably on described shell upper part (2)(74), this dismounting extension is connected and has operative end on top with the upper end of described dismounting guiding valve (72) in bottom(78)；
-be arranged in described shell upper part (2), the terminal backstop that is fixedly connected with described shell upper part (2) regularly(32) with the terminal stop element being connected with described driving element (34), move down for limiting described driving element (34)(38)；
-disconnected coupling device (44) between described drive unit and described driving element (34), this disconnected coupling device is in described terminalStop element (38) reclines described in described terminal backstop (32) and described executive component (4) continue to make when mobile along direction of operatingDriving element (34) and the disconnected connection of described drive unit; With
-with the bottom backstop (27) that described drive unit can be coupled, this bottom backstop is in described driving element (34) and instituteThe operative end (78) of encountering described dismounting extension (74) while stating drive unit by the disconnected connection of described disconnected coupling device (44), so thatContinue when mobile along direction of operating at described executive component (4), described dismounting extension (74) make described dismounting guiding valve (72) toLower movement.
2. pipettor according to claim 1, wherein, described drive unit has on the lifting arm of this drive unitStop element (25), top backstop (8) and bottom backstop (27), described stop element (25) at described top backstop andRemovable between the backstop of described bottom, to implement dosage stroke, wherein, described bottom backstop (27) is by super stroke bulletSpring (31) is supported in described shell upper part (2), to grasp by described executive component (4) edge after implementing dosage strokeThe elastic force that the described super stroke spring of opposing (31) is moved in the continuation of making direction passes through institute until arrive described terminal backstop (32)Stating terminal stop element (38) implements super stroke and described dismounting extension (74) is moved down.
3. pipettor according to claim 2, wherein, described top backstop (8) can in described shell upper part (2)Mobile, and described shell upper part (2) have the adjusting device (4,9,10) that is coupled mutually with described top backstop (8) forRegulate position and the definite dosage stroke of described top backstop (8) in described shell upper part (2).
4. according to the pipettor described in claim 2 or 3, wherein, described stop element (25) is the periphery of described lifting arm (6)On flange, described lifting arm (6) extends through passage (7) and the described bottom backstop on the top of described top backstop (8)The passage (28) of body (27), and described flange is arranged between described top backstop (8) and described bottom backstop (27).
5. pipettor according to claim 2, wherein, described disconnected coupling device (44) has two disconnected connection elements, Qi ZhongyiIndividual disconnected element is connected with described drive unit and another disconnected connection element is connected with described driving element (34), wherein, and theseThe releasably combination in a definite link position of disconnected connection element, and can be each other after overcoming definite confining force fromOpen and can be moved back into described link position.
6. pipettor according to claim 5, wherein, described disconnected element comprises two magnet or magnet and oneFerromagnetic counterpart and/or pawl device and/or spring assembly, these two magnet or magnet and ferromagnetic counterpart and/Or pawl device and/or spring assembly releasably remain on described disconnected element in described link position.
7. pipettor according to claim 5, wherein, described driving element (34) is sleeve, the bottom peace of this sleevePut on described contact element (63); And one of them of the disconnected element of described disconnected coupling device (44) is arranged on described sleeveIn and be fixedly connected with and be designed to the top disconnected connection element of the through hole with top with this sleeve; And described disconnected coupling device(44) another disconnected connection element is arranged on movably in described sleeve and is designed to be fixed on the bottom of lifting arm (6)On disconnected element, described lifting arm enters described sleeve and extends through the through hole on top from top; And described sleeveExtend through the through hole (33) of described terminal backstop (32) and have the other flange (38) radially outward stretching out, this in additionFlange limit moving downward of described driving element (34) by being placed on the upside of described terminal backstop (32).
8. pipettor according to claim 7 wherein, is provided with under the disconnected connection element of described bottom in described sleeveDisconnected connection spring (43), is supported in described sleeve by bottom disconnected connection element described in this disconnected connection spring.
9. pipettor according to claim 7, wherein, described sleeve has lower sleeve portion section (36) and upper sleeve section(35), wherein, the diameter that described lower sleeve portion section (36) has is less than the diameter of described upper sleeve section (35), this lower sleeve portionSection extends through the upper case opening (67) of described outer casing underpart part (3) and is placed in described contact element with bottom(63) upper, and described disconnected element is arranged in described upper sleeve section (35).
10. pipettor according to claim 7, wherein, described super stroke spring (31) props up in described shell upper partSupport is on the super stroke supporting device of the spring (32) of annular; Described sleeve steering is by described super stroke supporting device of the spring(32) through hole (33); And described super stroke supporting device of the spring (32) be the flange (38) for described sleeve terminal onlyGear.
11. pipettors according to claim 1, wherein, in the time that super stroke finishes or in the operation of described executive component (4) edgeWhen direction starts to continue to move, the outward flange that described bottom backstop (27) extends laterally with it is placed in described dismounting extension(74) operative end (78) is upper, to described dismounting extension (74) is moved down as drivening piece.
12. pipettors according to claim 10, wherein, described dismounting extension (74) passes through at described shell upper part(2) the dismounting spring (81) being arranged under described super stroke supporting device of the spring (32) is supported on described shell upper part(2) in.
13. pipettors according to claim 12, wherein, described dismounting spring (81) prolongs in described dismounting in upper supportBeing arranged on the top dismounting supporting device of the spring (77) under described super stroke supporting device of the spring (32) in length portion (74)And be arranged on bottom in described shell upper part (2) and that be fixedly connected with this shell upper part dismounting in lower supportOn supporting device of the spring (80).
14. pipettors according to claim 13, wherein, described dismounting guiding valve (72) is pulling off sleeves, this pulling off sleevesThere are multiple parallel removal rods in outside in the upper guiding of described outer casing underpart part (3) and/or described dismounting extension (74)(75), supporting device of the spring is dismantled on these removal rods top by annular in the distance apart from described dismounting guiding valve (72)And connected with each other (77).
15. according to the pipettor described in any one of claims 1 to 3, and wherein, described dismounting guiding valve (72) and described dismounting are prolongedLength portion (74) is by least one buckle connecting device and connected with each other.
16. pipettor according to claim 15, wherein, described dismounting extension (74) is by the first buckle connecting deviceBe connected with stripping ring (76), and this stripping ring (76) is connected with described dismounting guiding valve (72) by the second buckle connecting device.
17. pipettors according to claim 8, wherein, described super stroke spring (31) and/or described disconnected spring (43)Helical spring and/or volute spring.
18. pipettors according to claim 12, wherein, described dismounting spring (81) is helical spring and/or Conical ProjectileSpring.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102012002169.0A DE102012002169B4 (en) | 2012-02-07 | 2012-02-07 | pipette |
| DE102012002169.0 | 2012-02-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103447104A CN103447104A (en) | 2013-12-18 |
| CN103447104B true CN103447104B (en) | 2016-05-18 |
Family
ID=47623907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310139484.3A Active CN103447104B (en) | 2012-02-07 | 2013-02-07 | Pipettor |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2626134B1 (en) |
| CN (1) | CN103447104B (en) |
| DE (1) | DE102012002169B4 (en) |
| PL (1) | PL2626134T3 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102014109345A1 (en) | 2014-07-04 | 2016-01-07 | Eppendorf Ag | Pipette for actuating a syringe |
| DE102016121813A1 (en) * | 2016-11-14 | 2018-05-17 | Ika-Werke Gmbh & Co. Kg | Pipette and method for adjusting a volume of a pipette to be pipetted |
| DE202017101008U1 (en) * | 2017-02-23 | 2018-05-24 | Brand Gmbh + Co Kg | Dispenser and system for receiving and dispensing fluid volumes |
| PL3680017T3 (en) * | 2019-01-08 | 2022-02-07 | Eppendorf Ag | Pipette for use with a pipette tip |
| JP7315625B2 (en) * | 2020-07-14 | 2023-07-26 | エッペンドルフ エスイー | Pipettes for use with pipette tips with integral plungers |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0181957A1 (en) * | 1984-11-20 | 1986-05-28 | HTL High-Tech Lab Herstellung und Vertrieb medizinisch technischer Erzeugnisse GmbH | Adjustable-volume pipette |
| US5012682A (en) * | 1988-10-21 | 1991-05-07 | Firma Eppendorf-Netheler-Hinz Gmbh | Pipetting device |
| US5511433A (en) * | 1990-05-04 | 1996-04-30 | Eppendorf-Netherler-Hinz Gmbh | Pipette device |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2319175A1 (en) * | 1973-04-16 | 1974-10-31 | Oxford Lab | DETAIL PISTON PIPETTE |
| DE2549477C3 (en) * | 1975-11-05 | 1982-01-07 | Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg | Pipetting device |
| DE19708151C2 (en) | 1997-02-28 | 1999-05-27 | Eppendorf Geraetebau Netheler | Pipetting device |
| DE102004003434B4 (en) | 2004-01-21 | 2006-06-08 | Eppendorf Ag | Pipetting device with a displacement device and a drive device detachably connected thereto |
| DE102005041183B3 (en) * | 2005-08-31 | 2007-01-04 | Eppendorf Ag | Two-part pipetting system for metering liquids, has lower spigot which is secured in its holder by snap hooks with catches and released by wedge system actuated by movement of unlocking ring |
-
2012
- 2012-02-07 DE DE102012002169.0A patent/DE102012002169B4/en active Active
-
2013
- 2013-01-26 EP EP13000386.6A patent/EP2626134B1/en active Active
- 2013-01-26 PL PL13000386T patent/PL2626134T3/en unknown
- 2013-02-07 CN CN201310139484.3A patent/CN103447104B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0181957A1 (en) * | 1984-11-20 | 1986-05-28 | HTL High-Tech Lab Herstellung und Vertrieb medizinisch technischer Erzeugnisse GmbH | Adjustable-volume pipette |
| US5012682A (en) * | 1988-10-21 | 1991-05-07 | Firma Eppendorf-Netheler-Hinz Gmbh | Pipetting device |
| US5511433A (en) * | 1990-05-04 | 1996-04-30 | Eppendorf-Netherler-Hinz Gmbh | Pipette device |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2626134A3 (en) | 2013-11-06 |
| DE102012002169A1 (en) | 2013-08-08 |
| DE102012002169B4 (en) | 2017-02-09 |
| PL2626134T3 (en) | 2017-08-31 |
| EP2626134B1 (en) | 2017-03-01 |
| EP2626134A2 (en) | 2013-08-14 |
| CN103447104A (en) | 2013-12-18 |
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