CN103462733A - Blood vessel support - Google Patents
Blood vessel support Download PDFInfo
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- CN103462733A CN103462733A CN2013104631484A CN201310463148A CN103462733A CN 103462733 A CN103462733 A CN 103462733A CN 2013104631484 A CN2013104631484 A CN 2013104631484A CN 201310463148 A CN201310463148 A CN 201310463148A CN 103462733 A CN103462733 A CN 103462733A
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- support
- circular cone
- blood vessel
- intravascular stent
- silk material
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Abstract
The invention discloses a blood vessel support, which is made of stainless steel, Ni-Ti alloy, platinum, gold, a degradable biological material, multiple layers of composite materials and the like; the machining mode comprises the steps of weaving, cutting, carving, natural molding, second machining molding and the like. The invention overcomes multiple defects of the existing blood vessel support products in the market, and provides a blood vessel support capable of solving the problem that the tissue of the blood vessel wall is damaged due to two telescopic ends of the blood vessel support (forced by expanding and shrinking of the blood vessel), the problem of relative displacement between the blood vessel support and the blood vessel and the problem that the axial and radial forces of the blood vessel support can not be set according to the needs of the blood vessel. The blood vessel support realizes the low production cost, simple production process, absolute quality guarantee, simple operation of medical staff and ensured functions.
Description
Technical field
The present invention relates to a kind of cardiovascular disease interventional therapy device, the design organization that is specifically related to intravascular stent can be that transition is fitted and is difficult for injured blood vessel with difficult circular cone and the blood vessel that relative positioning, support two-port occur of blood vessel in blood vessel, belongs to technical field of medical instruments.
Background technology
At present, the common disease of cardiovascular and cerebrovascular vessel mainly contains stricture of artery, aneurysm etc., if these diseases treat not in time and may cause blood vessel blockage, tumor body to break, by the serious harm mankind's life security.For aneurysmal treatment, the early stage main surgical operation such as adopt excision or folder to close.
The support interventional procedure is one of Main Means of Cardiovarscular at present, and widely used intravascular stent mainly contains bare metal stent and bracket for eluting medicament clinically.Bare metal stent has been obtained the curative effect attracted people's attention after entering clinical treatment, but the application through more than ten years also exposes some shortcomings and disadvantage gradually, as easy hyperamization bolt forms, restenosis rate is high, cause vascular damaged etc., clinical research to show that bare metal stent implants latter 6 months in-stent restenosis incidence rates up to 20%～30%.The application of drug-eluting stent, make restenosis rate in postoperative 1 year drop to below 10%, but clinical research shows, the bracket for eluting medicament late result is not good, easily forms thrombosis, and case fatality rate or the heart infarction incidence rate higher.The in-stent restenosis problem has had a strong impact on patient's quality of life and life and health, is technical barrier urgently to be resolved hurrily.
It is one of basic reason of bringing out in-stent restenosis that expansion when support is implanted causes the local vascular damage.Expansion when existing bare metal stent, bracket for eluting medicament, Biodegradable scaffold are implanted all can cause blood vessel injury in various degree.Find by prior art documents, China Patent No.: 200620057977.8, this patent discloses a kind of intravascular stent, its structure is: the support support body adopts nitinol alloy wire to make, there is the multi-layer corrugated circulus metal master of arranging vertically, adjacent two layers metallic supports interlaced arrangement.And for example: China Patent No.: 200910199194.1, this patent discloses a kind of intravascular stent, and its structure is: have the cast vessel-like, the support outer wall surface is with thin film, but this support has good mechanical performance transporting and antiseep.And for example: China Patent No.: 201210111453.2, this patent discloses the support matrix consisted of marmem and the mechanical impedance system formed by Biodegradable material, wherein, the braiding of support matrix adopting shape-memory alloy wire is welded after forming or adopt the cutting of marmem thin plate, through axially stretching, make its axial elongation, radially shorten, then carry out compoundly with Biodegradable material, form integrated composite construction.And for example: China Patent No.: 201110446841.1, this braided support is formed by the braiding of multi-filament material, it is characterized in that, according to the silk material radical of this braided support, the silk material of the end of this braided support is divided into some strands, and wherein each rhizoid material in per share silk material is fixed together.China Patent No.: 201020659169.5, relate to a kind of Intracranial temporary bracket, described support is the TRS formed by the memory alloy wire braiding, the mid portion of described support is columniform flat segments, the two ends of described support are conical cone sections, described cone section seamlessly transits with the joint of described flat segments, is fixed together the top that forms described conical cone section at the end of the described memory alloy wire of described support one end.
This intravascular stent still can't overcome the vascular wall tissue damage problem caused due to support two ends flexible (blood vessel self swells and shrinks and is forced to), support neither one design organization in blood vessel comes fine assurance support and blood vessel relative displacement can not occur, and intravascular stent is axial, radial force can not need to change according to blood vessel.
Summary of the invention
Adopt the design of breakthrough Traditional Thinking in order to overcome the above problems the present invention, the present invention seeks to have overcome on market existing intravascular stent product much not enough, a kind of novel problem that can overcome the vascular wall tissue damage caused due to intravascular stent two ends flexible (blood vessel self swells and shrinks and is forced to) is provided, the problem of intravascular stent intravascular stent and blood vessel generation relative displacement in blood vessel, intravascular stent axially, the radial force problem that can not need to arrange according to blood vessel.The present invention has realized that production cost is low, production technology is simple, quality definitely guarantees, medical personnel are simple to operate, function can guarantee.
The present invention can realize in the following manner:
A kind of intravascular stent is comprised of support circular cone one, support cylinder one, bracket tab ring, support cylinder two, support circular cone two, its material is: rustless steel, Nitinol, platinum, gold, degradable biomaterial, multilayer materials etc., and its processing mode is: braiding, cutting, engraving, natural molding, secondary operations molding etc.; Can reduce the vascular wall tissue damage, support and blood vessel can keep relative displacement.It is characterized in that: support circular cone one is positioned at an end of intravascular stent, support cylinder one is between support circular cone one and bracket tab ring, the bracket tab ring is between support cylinder one and support cylinder two, support cylinder two is between bracket tab ring and support circular cone two, and support circular cone two is positioned at the other end of intravascular stent; Support circular cone one is similar with support circular cone two and is taper shape, less the closer to its diameter of support port, bracket end silk material head end is (arc transition is arranged) that acute angle or obtuse angle have been processed, bracket end silk material head end is free state, from support circular cone one end face, to the whole rack bore of support circular cone biend, connects; Support cylinder one and support cylinder two are similar and for cylindrical, can be considered one one or more bracket tab rings that just superposeed thereon; The bracket tab ring is ring-type, and its convex cross section is circular arc or polygon or circular arc and polygonal in conjunction with shape.
According to intravascular stent of the present invention, it is characterized in that: support has very strong elastic memory, under certain external influence power, elastic deformation can occur, under free state, the diameter dimension pass is bracket end mouth diameter<support cylinder one diameter<frame protruding ring diameter, as Fig. 1.
According to intravascular stent of the present invention, it is characterized in that: the silk material interlocks each other, and its staggered angle is transformable (helix pitch that is taenidium material 10 is transformable), and the reticulated cell of its formation also changes, but the support axial stretching.
Fig. 5, Fig. 6 are the structures be derived on Fig. 1 basis, appearance profile two ends port is less than normal, there is (one or more) projection centre, under free state, diameter dimension closes and is: G<H<I, it connects, and excessively place is for smooth excessive, and the appearance profile line 20 of axis direction is that circular curve or various curve connect.
Scheme of the invention two:
Intravascular stent of the present invention is comprised of support circular cone, the bracket tab ring at two ends, the support cylinder at two ends.According to the present invention, provide a kind of intravascular stent can reduce the vascular wall tissue damage, support and blood vessel can keep relative displacement.It is characterized in that: the support circular cone is positioned at the two ends of intravascular stent, and protruding ring is between support circular cone and support cylinder, and protruding ring is positioned at the two ends of support cylinder; The support circular cone is conical, less the closer to its diameter of support port, bracket end silk material head end is (being arc transition) that acute angle or obtuse angle have been processed, bracket end silk material head end is free state, and the whole rack bore of port from a port of support circular cone to other end support circular cone connects.
According to intravascular stent of the present invention, it is characterized in that: intravascular stent has very strong elastic memory, under certain external influence power, elastic deformation can occur, under free state, diameter dimension closes and is: bracket end silk material head end diameter<protruding ring diameter, support body diameter<protruding ring diameter, (Fig. 7).
Scheme of the invention three:
It is characterized in that: local silk material is interrupted, the silk material interrupted forms silk material warpage fracture 21, the head end of silk material warpage fracture 21 is interrupted rear formation bulb-type, silk material warpage fracture 21 outside warpages, the included angle A that itself and intravascular stent axially form<90 °, silk material warpage fracture 21 penetrates blood vessel and plays the intravascular stent axial location in blood vessel.
Scheme of the invention four:
It is characterized in that: local silk material is interrupted, the silk material interrupted forms silk material fracture 23, interrupted local silk material and be removed a part, form close section 22 and rare section 24 of intravascular stent, the head end of silk material fracture 23 is interrupted rear formation bulb-type, and close section 22 of intravascular stent and rare section 24 have obvious variation (>=10%) aspect axial, radial force.
A kind of intravascular stent of the present invention, its material is: rustless steel, Nitinol, platinum, gold, degradable biomaterial, multilayer materials etc., its processing mode is: braiding, cutting, engraving, natural molding, secondary operations molding etc.The present invention seeks to have overcome on market existing intravascular stent product much not enough, a kind of novel problem that can overcome the vascular wall tissue damage caused due to intravascular stent two ends flexible (blood vessel self swells and shrinks and is forced to) is provided, the problem of intravascular stent intravascular stent and blood vessel generation relative displacement in blood vessel, intravascular stent axially, the radial force problem that can not need to arrange according to blood vessel.The present invention has realized that production cost is low, production technology is simple, quality definitely guarantees, medical personnel are simple to operate, function can guarantee.
The invention has the advantages that: a kind of novel intravascular stent is provided, can overcome the problem of the vascular wall tissue damage caused due to intravascular stent two ends flexible (blood vessel self swells and shrinks and is forced to), the problem of intravascular stent intravascular stent and blood vessel generation relative displacement in blood vessel, intravascular stent axially, the radial force problem that can not need to arrange according to blood vessel.The present invention has realized that production cost is low, production technology is simple, quality definitely guarantees, medical personnel are simple to operate, function can guarantee.
The accompanying drawing explanation
Fig. 1: be the present invention program's one intravascular stent free state structural representation
Fig. 2: be the present invention program's one intravascular stent generalized section while supporting in blood vessel
Fig. 3: be the present invention program's one intravascular stent free state 3 D stereo schematic diagram
Fig. 4: the enlarged diagram that is the I place
Fig. 5: be the present invention program's one intravascular stent free state structural representation
Fig. 6: be the present invention program's one intravascular stent free state structural representation
Fig. 7: be the present invention program's two intravascular stent free state structural representations
Fig. 8: be the present invention program's two intravascular stent free state 3 D stereo schematic diagrams
Fig. 9: be the present invention program's two intravascular stents generalized sections while supporting in blood vessel
Figure 10: be the present invention program's three intravascular stent free state structural representations
Figure 11: be the present invention program's four intravascular stent free state structural representations
Figure 12: be the present invention program's four intravascular stent free state structural representations
in figure:01, support circular cone one, 02, support cylinder one, 03, bracket tab ring, 04, support cylinder two, 05, support circular cone two, 06, blood vessel, 07, support port, 08, blood vessel projection, 10, the silk material, 11, bracket end silk material head end, 12, support circular cone, 13, bracket tab ring, 14, the support cylinder, 15, the support port, 16, blood vessel projection, 17, bracket end silk material head end, 18, blood vessel, 20, contour line, 21, silk material warpage fracture, 22, rare section, 23, silk material fracture, 24, close section.
the specific embodiment:
Below in conjunction with accompanying drawing 1-12, the present invention is described in detail, and the technical scheme in the embodiment of the present invention is clearly and completely described, and obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making under the creative work prerequisite the every other embodiment obtained, belong to the scope of protection of the invention.
Scheme of the invention one:
The present invention can overcome the vascular wall tissue damage problem caused due to intravascular stent two ends flexible (blood vessel self swells and shrinks and is forced to), and intravascular stent is intravascular stent and blood vessel generation relative displacement problem in blood vessel.The present invention is designed with one or more bracket tab rings 03 on support cylinder 1 and support cylinder 2 04, bracket tab ring 03 is projection in blood vessel, make vascularization blood vessel projection 08, bracket tab ring 03 is set in the groove of blood vessel projection 08, and intravascular stent intravascular stent and blood vessel in blood vessel relative displacement can not occur, support circular cone 1 and support circular cone 2 05 are conical, less the closer to support port 07 its diameter, bracket end silk material head end 11 (arc transition is arranged) for going to acute angle or obtuse angle to process, this processing can reduce the damage of support to blood vessel, support circular cone 1 and support circular cone 2 05 are the transition laminatings with blood vessel, bracket end silk material head end 11 is free state, support two-port 07, support circular cone 1, support circular cone 2 05 can free-extension in blood vessel, bracket end silk material head end 11 can not penetrate easily blood vessel 06(and be difficult for injured blood vessel), from support circular cone one 01 end faces to the support circular cone, the whole intravascular stent inner chamber of 2 05 end face connects, and guarantees that blood connects in blood vessel and in the intravascular stent inner chamber.Intravascular stent of the present invention is to send into blood vessel by carrier, and this intravascular stent is compressive state in carrier, is similar to cylindrical.
Scheme of the invention two:
The present invention can overcome the vascular wall tissue damage problem caused due to intravascular stent two ends flexible (blood vessel self swells and shrinks and is forced to), and intravascular stent is intravascular stent and blood vessel generation relative displacement problem in blood vessel.Bracket tab ring 13 of the present invention is projection in blood vessel, makes vascularization blood vessel projection 16, and bracket tab ring 13 is set in the groove of blood vessel projection 16, and intravascular stent intravascular stent and blood vessel in blood vessel relative displacement can not occur; Support circular cone 12 is conical, less the closer to support port 15 its diameters, bracket end silk material head end 17 (arc transition is arranged) for going to acute angle or obtuse angle to process, this processing can reduce the damage of support to blood vessel, support circular cone 12 is the transition laminating with blood vessel, bracket end silk material head end 17 is free state, and support two-port 15, support circular cone 12 can free-extensions in blood vessel, and bracket end silk material head end 17 can not penetrate easily blood vessel 18(and be difficult for injured blood vessel).Intravascular stent of the present invention is to send into blood vessel by carrier, and this intravascular stent is compressive state in carrier, is similar to cylindrical.
Scheme of the invention three:
Intravascular stent of the present invention is that a local silk material is interrupted on the present invention program one basis, and it is cutting mode that a local silk material is interrupted the mode interrupted, and a silk material is chosen one section from support network outwards allows its warpage.Silk material warpage fracture 21 penetrates blood vessel and plays the intravascular stent axial location in blood vessel.
Scheme of the invention four:
Intravascular stent of the present invention is that local silk material is interrupted on the present invention program one basis, it is cutting mode that local silk material is interrupted the mode interrupted, the silk material is taken out one section (reduce the density of a material, regulate axial, the radial force of intravascular stent) from support network.A kind of axial, radial force of intravascular stent need to arrange a material density according to blood vessel.The pitch (PPI value) axial, that radial force can also change a material of intravascular stent is regulated.
But the combination of the inventive features local feature in several scheme of the invention of the present invention or combined crosswise, just do not doing concrete the introduction here, but the combination of inventive features also belongs to the present invention.
To the above-mentioned explanation of the disclosed embodiments, make professional and technical personnel in the field can realize or use the present invention.Multiple modification to these embodiment will be apparent for those skilled in the art, and General Principle as defined herein can be in the situation that do not break away from the spirit or scope of the present invention, realization in other embodiments.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (7)
1. an intravascular stent, is characterized in that: support circular cone one (01), support cylinder one (02), bracket tab ring (03), support cylinder two (04), support circular cone two (05), consist of; Described support circular cone one (01) is positioned at an end of intravascular stent, support cylinder one (02) is positioned between support circular cone one (01) and bracket tab ring (03), bracket tab ring (03) is positioned between support cylinder one (02) and support cylinder two (04), support cylinder two (04) is positioned between bracket tab ring (03) and support circular cone two (05), and support circular cone two (05) is positioned at the other end of intravascular stent; Support circular cone one (01) and support circular cone two (05) are to be taper shape, less the closer to its diameter of support port (07), bracket end silk material head end (11) is arc transition, from support circular cone one (01) end face, to the whole rack bore of support circular cone two (05) end face, connects; Support cylinder one (02) and support cylinder two (04) are cylindrical, and bracket tab ring (03) is ring-type, and its convex cross section is circular arc or polygon or circular arc and polygonal in conjunction with shape.
2. intravascular stent according to claim 1 is characterized in that: under free state, diameter dimension closes and is: support port (07) diameter<support cylinder one (02) diameter<frame protruding ring (03) diameter.
3. intravascular stent according to claim 1, it is characterized in that: described support circular cone one (01), support cylinder one (02), bracket tab ring (03), support cylinder two (04), support circular cone two (05) are by interlaced formation of silk material (10), and intravascular stent can axial stretching.
4. an intravascular stent, it is characterized in that: support circular cone (12), the bracket tab ring (13) at two ends, support cylinder (14) by two ends form, described support circular cone (12) is positioned at the two ends of intravascular stent, protruding ring (13) is positioned between support circular cone (12) and support cylinder (14), and protruding ring (13) is positioned at the two ends of support cylinder (14); Support circular cone (14) is conical, less the closer to its diameter of support port (15), bracket end silk material head end (17) is arc transition, bracket end silk material head end (17) is free state, and the whole rack bore of port from a port of support circular cone to other end support circular cone connects.
5. intravascular stent according to claim 4, it is characterized in that: described intravascular stent has very strong elastic memory, and under free state, diameter dimension closes and is: bracket end silk material head end (17) diameter<protruding ring (13) diameter, support cylinder (14) diameter<protruding ring (13) diameter.
6. an intravascular stent, it is characterized in that: by support circular cone one (01), support cylinder one (02), support cylinder two (04), support circular cone two (05), formed, from support circular cone one (01) end face, to the whole rack bore of support circular cone two (05) end face, connect, a silk material is chosen one section from support network outwards allows its warpage; Local silk material is interrupted, the silk material interrupted forms silk material warpage fracture (21), the head end of silk material warpage fracture (21) is interrupted rear formation bulb-type, silk material warpage fracture (21) is warpage outwards, the included angle A that itself and intravascular stent axially form<90 °, silk material warpage fracture (21) penetrates blood vessel and plays the intravascular stent axial location in blood vessel.
7. an intravascular stent, it is characterized in that: by support circular cone one (01), support cylinder one (02), support cylinder two (04), support circular cone two (05), formed, from support circular cone one (01) end face, to the whole rack bore of support circular cone two (05) end face, connect, local silk material is interrupted, and the silk material is taken out one section from support network; The silk material interrupted forms silk material fracture (23), is interrupted local silk material and is removed a part, forms close section (22) and rare section (24) of intravascular stent, and the head end of silk material fracture 23 is interrupted rear formation bulb-type.
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| CN201310463148.4A CN103462733B (en) | 2013-10-08 | 2013-10-08 | Intravascular stent |
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| CN201310463148.4A CN103462733B (en) | 2013-10-08 | 2013-10-08 | Intravascular stent |
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| CN103462733B CN103462733B (en) | 2016-02-03 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105559945A (en) * | 2016-02-29 | 2016-05-11 | 微创心脉医疗科技（上海）有限公司 | Covered stent and manufacturing method thereof |
| CN107106286A (en) * | 2014-12-31 | 2017-08-29 | C·R·巴德公司 | Expandable stent with constrained end |
| CN110731834A (en) * | 2019-10-25 | 2020-01-31 | 郑州美港高科生物科技有限公司 | Iron-base alloy renal artery stent |
| CN113288579A (en) * | 2021-06-21 | 2021-08-24 | 卢国华 | Novel artificial lacrimal duct |
| WO2023104103A1 (en) * | 2021-12-10 | 2023-06-15 | 聚辉医疗科技(深圳)有限公司 | Flow diverter stent and system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107106286A (en) * | 2014-12-31 | 2017-08-29 | C·R·巴德公司 | Expandable stent with constrained end |
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| CN113288579A (en) * | 2021-06-21 | 2021-08-24 | 卢国华 | Novel artificial lacrimal duct |
| CN113288579B (en) * | 2021-06-21 | 2022-07-12 | 卢国华 | Novel artificial lacrimal duct |
| WO2023104103A1 (en) * | 2021-12-10 | 2023-06-15 | 聚辉医疗科技(深圳)有限公司 | Flow diverter stent and system |
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| CN103462733B (en) | 2016-02-03 |
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