CN103519882A - Multi-electrode renal artery ablation catheter - Google Patents

Multi-electrode renal artery ablation catheter Download PDF

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Publication number
CN103519882A
CN103519882A CN201210233475.6A CN201210233475A CN103519882A CN 103519882 A CN103519882 A CN 103519882A CN 201210233475 A CN201210233475 A CN 201210233475A CN 103519882 A CN103519882 A CN 103519882A
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ablation
ablation catheter
skeleton
renal artery
catheter
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CN103519882B (en
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李莉
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Abstract

Disclosed is a multi-electrode renal artery ablation catheter. The multi-electrode renal artery ablation catheter is used for renal artery sympathetic nerve ablation in the high blood pressure interventional therapy, and comprises an adjustable curved catheter sheath, an adjustable-diameter ablation catheter body and a functional handle, wherein the head end of the adjustable curved catheter sheath can be curved, and the ablation catheter body can conveniently enter a renal artery. The diameter of a skeleton of the adjustable-diameter ablation catheter body is adjustable. The multi-electrode renal artery ablation catheter is provided with a plurality of electrodes. Each electrode is provided with a temperature sensor. According to the multi-electrode renal artery ablation catheter, a plurality of points can be ablated in a one-off mode, the ablation points are not continuous, the temperature is controllable, when the high blood pressure is treated by removing renal artery sympathetic nerves, the risk caused by excessive ablation and narrow renal artery blood vessels is avoided, meanwhile due to the one-time ablation, the operation time and the usage of X rays can be greatly reduced, and the accuracy of the ablation is improved.

Description

The multipole ablation catheter of renal artery
Technical field
The present invention relates to medical instruments field, be specifically related to a kind of renal artery sympathetic nerve ablation catheter for hypertension interventional therapy.
Background technology
Intractable hypertension, refers to that the Drug therapy (comprising 3 kinds of depressor therapeutic alliances of diuretic) at maximum tolerated dose still cannot reach target pressure value.These patients are High risk groups of major cardiovascular events.
In April, 2009, Krum etc. have reported the new technique of percutaneous catheter kidney sympathetic nerve radiofrequency ablation intractable hypertension.The method is cut off kidney sympathetic nerve by radio-frequency (RF) ablation, and does not affect other abdominal paries, pelvis or lower limb nerve domination, has reached the object of avoiding severe complication in blood pressure lowering.In November, 2010, one relates to perspective, the randomized controlled trial that carry out 24 medical centers, and " Symplicity HTN-2 research " is published in lancet." Symplicity HTN-2 research " result shows, refractory hypertension patient is carried out, through conduit TSD, can obtaining remarkable and lasting efficacy of antihypertensive treatment.106 routine refractory hypertension patients are included in this test altogether in, and test group patient all adheres to carrying out multiple medicines associating antihypertensive therapy after carrying out RSD, and matched group patient only carries out multiple medicines therapeutic alliance.Test group patient's blood pressure in the time of 6th month 32/12mmHg that on average declined, matched group patient blood pressure is all without changing.And complication or the adverse events that operation is relevant do not found in research, and operation in patients metanephros function status is good.
As a new technology, the apparatus matching also relatively lacks, at present for clinical product, also there are problems, the more product of use is the Symplicity ablation system of Medtronic company clinically, because only having an electrode ablation, cause operation more complicated, the problems such as radio-frequency (RF) ablation time length.
CN102274074A discloses a kind of Multi-electrode open-type radio frequency ablation catheter, and one end of conduit is Open architecture, and what the problem that easy generation can not fit tightly with blood vessel when renal artery goes sympathetic nerve to melt and causing melted failure may.CN201469401U discloses a kind of helical form renal artery sympathetic nerve frequency ablation electrode catheter, and electrode is helical structure, and simplicity of design is difficult to operation, has equally can not fit tightly the problem of blood vessel and cause melting the risk of failure.
Summary of the invention
The renal artery sympathetic nerve ablation catheter that the object of this invention is to provide a kind of simple to operate, dependable performance.According to arteriorenal anatomical structure, the present invention can provide the electrode of ablation catheter to fit tightly renal artery blood vessel, and diameter is adjustable, and the conduit that a plurality of electrodes melt simultaneously can significantly reduce the consumption of X ray, has reduced operation easier simultaneously.
For achieving the above object, the invention provides the multipole ablation catheter of a kind of renal artery, the ablation catheter and the function handle that comprise adjustable bent catheter sheath, adjustable diameter, described adjustable bent catheter sheath one end is fixed on the crooked control piece of function handle, controls the free bend of the other end by crooked control piece; The skeleton that comprises at least two adjustable diameters of the ablation catheter of described adjustable diameter, on every skeleton straight section, fix at least one electrode, each electrode is connected with the ablation apparatus interface of function handle by wire, ablation catheter one end is fixed in described skeleton one end, the other end be fixed on can the skeleton connector with respect to ablation catheter activity on, skeleton control valve one end of described ablation catheter is connected with head end part through skeleton connector, the other end is fixed on the skeleton control piece of function handle, and described skeleton control piece can be controlled the diameter adjustment of described skeleton; One end of the ablation catheter of described adjustable diameter is fixed on the ablation catheter extension and contraction control part of function handle, and the skeleton that can realize described ablation catheter by ablation catheter extension and contraction control part passes in and out described adjustable bent catheter sheath.
The framing structure of described adjustable diameter is straight section in the middle of being, two ends are contracted to the Rugby structure of a bit.
The skeleton of described adjustable diameter is 2~8, more preferably 3~4.
The skeleton straight section length of described adjustable diameter is 10~30mm, according to arteriorenal length, more preferably 15~20mm.
On the straight section of the skeleton of described adjustable diameter, be fixed with 1~3 electrode, can be on each skeleton, to have 1 electrode, and in another plane, be not staggered, also can be 1~2 electrode that distributes on adjacent skeleton, and in another plane, be not staggered, each electrode connects a wire, and the other end is connected with the ablation apparatus interface of function handle, by radio-frequency (RF) ablation energy delivery to electrode.
The diameter of the skeleton of described adjustable diameter straight section from described adjustable bent catheter sheath discharges is 3~10mm, according to arteriorenal normal dia, more preferably 3~8mm.
Described adjustable bending pipe sheath is double lumen structure, a logical ablation catheter of tube chamber, a logical traction fiber of tube chamber, traction fiber one end in described adjustable bending pipe sheath is fixed on the end of adjustable bending pipe sheath, the other end is fixed on the traction fiber fixture of function handle, can realize by controlling the movement of traction fiber fixture the free bend of adjustable bending pipe sheath, preferred angle of bend is spent 0~90, thereby ablation catheter can be entered in renal artery easily.
On described function handle, be provided with ablation apparatus interface, each electrode is connected with described ablation apparatus interface by wire, and described ablation apparatus interface can be realized and being connected of radio-frequency (RF) ablation instrument by connecting line, by transmission of radio-frequency energy to each electrode.More preferably, can choose different electrodes according to arteriorenal architectural feature melts.
Described each electrode is connected with temperature sensor, is connected, and can realizes and being connected of radio-frequency (RF) ablation instrument by connecting line by wire with described ablation apparatus interface, and the temperature signal of each electrode is presented on radio-frequency (RF) ablation instrument.
Radio frequency ablation catheter provided by the invention, can disposablely melt a plurality of points, and ablation points is discontinuous, temperature is controlled, treat the hypertensive while removing renal artery sympathetic nerve, avoided excessively melting the risk with renal artery angiostenosis, simultaneously because once melting, can greatly reduce the use of operating time and X ray, improve the accuracy melting.
Accompanying drawing explanation
Fig. 1 is the structural representation of the multipole ablation catheter of renal artery.
Fig. 2 is the structural representation of the multipole ablation catheter skeleton income of renal artery adjustable bending pipe sheath.
Fig. 3 is the multipole ablation catheter of the renal artery schematic diagram that skeleton does not discharge in vivo.
Fig. 4 is the multipole ablation catheter of the renal artery schematic diagram of skeleton after discharging in vivo.
The explanation of Reference numeral
1, adjustable bent catheter sheath; 2, adjustable diameter ablation catheter; 3, the skeleton of adjustable diameter; 4, electrode; 5, skeleton connector; 6, skeleton control valve; 7, head end part; 8, function handle; 9, crooked control piece; 10, ablation catheter extension and contraction control part; 11, skeleton control piece; 12, traction fiber fixture; 13, ablation apparatus interface; 14, aorta; 15, renal artery; 16, kidney; RS: renal artery sympathetic nerve (Renal Sympathetic).
The specific embodiment
Below in conjunction with drawings and Examples, the specific embodiment of the invention is described further, following examples are only for technical scheme of the present invention is more clearly described, and can not limit the scope of the invention with this.
Figure 1 shows that the guide-tube structure schematic diagram that the present invention is melted for renal artery sympathetic nerve.Described ablation catheter comprises ablation catheter 2 and the function handle 8 of adjustable bent catheter sheath 1, adjustable diameter, and described adjustable bent catheter sheath 1 one end is fixed on the crooked control piece of function handle 89, controls the free bend of the other ends by crooked control piece 9, the skeleton that comprises at least two adjustable diameters 3 of the ablation catheter 2 of described adjustable diameter, on every skeleton 3 straight sections, fix at least one electrode 4, each electrode 4 is connected with the ablation apparatus interface 13 of function handle 8 by wire, ablation catheter 2 one end are fixed in described skeleton 3 one end, the other end be fixed on can the skeleton connector 5 with respect to ablation catheter activity on, skeleton control valve 6 one end of described ablation catheter are connected with head end part 7 through skeleton connector 5, the other end is fixed on the skeleton control piece 11 of function handle 8, described skeleton control piece 11 can be controlled the diameter adjustment of described skeleton 3, one end of the ablation catheter 2 of described adjustable diameter is fixed on the ablation catheter extension and contraction control part 10 of function handle 8, can realize the described adjustable bent catheter sheath 1 of skeleton 3 turnover of described ablation catheter by ablation catheter extension and contraction control part 10.
Skeleton 3 structures of adjustable diameter are straight section in the middle of being, two ends are contracted to the Rugby structure of a bit, the skin of skeleton 3 is to have elastic macromolecule tubing, in each skeleton, there is sizing Nitinol, its diameter is 0.2~0.5mm, can make skeleton 3 discharge the shape of the rear maintenance design of adjustable bent catheter sheath 1.
The skeleton 3 of adjustable diameter is 2~8, more preferably 3~4, its straight section length is 10~30mm, according to the length of renal artery 15,15~20mm more preferably, on straight section, be fixed with 1~3 electrode 4, can be on each skeleton 3, to have 1 electrode 4, and in another plane, be not staggered, also can be 1~2 electrode 4 that distributes on adjacent skeleton 3, and in another plane, not be staggered, each electrode 4 connects a wire, the other end is connected with the ablation apparatus interface 13 of function handle 8, by radio-frequency (RF) ablation energy delivery to electrode 3.Described each electrode 3 is connected with temperature sensor, is connected, and can realizes and being connected of radio-frequency (RF) ablation instrument by connecting line by wire with described ablation apparatus interface 13, and the temperature signal of each electrode is presented on radio-frequency (RF) ablation instrument.
The skeleton 3 of adjustable diameter discharges from adjustable bent catheter sheath 1 by ablation catheter extension and contraction control part 10, and through skeleton control piece 11, carry out the diameter control of skeleton 3, can between 3~10mm, regulate, according to arteriorenal normal dia, more preferably between 3~8mm, regulate.
Adjustable bending pipe sheath 1 is double lumen structure, a logical ablation catheter 2 of tube chamber, a logical traction fiber of tube chamber, traction fiber one end is fixed on the end of adjustable bending pipe sheath 1, the other end is fixed on the traction fiber fixture 12 of function handle 8, can realize by controlling the movement of traction fiber fixture 12 free bend of adjustable bending pipe sheath 1, preferred angle of bend is spent 0~90, thereby ablation catheter 2 can be entered in renal artery easily.
On function handle 8, be provided with ablation apparatus interface 13, each electrode 4 is connected with ablation apparatus interface 13 by wire, and ablation apparatus interface 13 can be realized and being connected of radio-frequency (RF) ablation instrument by connecting line, by transmission of radio-frequency energy to each electrode 4.When reality is used, can choose different electrode 4 according to the architectural feature of renal artery 15 and melt.
 
Figure 2 shows that the structural representation of the multipole ablation catheter skeleton income of renal artery of the present invention adjustable bending pipe sheath, by promoting backward the ablation catheter extension and contraction control part 10 of function handle 8, the skeleton of ablation catheter 2 can be drawn in to adjustable bent catheter sheath 1, adjust skeleton control piece 11 simultaneously and make head end part 7 draw in adjustable bent catheter sheath 1, make its laminating closely.
Figure 3 shows that the multipole ablation catheter of the renal artery of the present invention schematic diagram that skeleton does not discharge in vivo, by the multipole ablation catheter skeleton 3 income adjustable bending pipe sheaths 1 of renal artery, pass through femoral artery puncture, under X ray guiding, enter aorta 14, ablation catheter is placed near renal artery 14 entrances, control the crooked control piece 9 of function handle 8, make the crooked suitable angle of adjustable bent catheter sheath 1, aim at renal artery 15 entrances, by adjustable bent catheter sheath 1 by promoting forward the ablation catheter extension and contraction control part 10 of function handle 8, make the skeleton 3 of ablation catheter 2 release adjustable bent catheter sheath 1, enter renal artery 15.
Figure 4 shows that the multipole ablation catheter of the renal artery of the present invention schematic diagram of skeleton after discharging in vivo.When the skeleton 3 of ablation catheter 2 enters after renal artery 15, promote backward skeleton control piece 11, make head end part 7 touch skeleton connector 5, make skeleton 3 be adjacent to the blood vessel wall of renal artery 15, whether suitable by X ray assess location, as improper in position, can adjust by ablation catheter extension and contraction control part 10 and skeleton control piece 11, after the ideal of position, ablation apparatus interface 13 be connected to radiofrequency melting instrument, set parameter, melt.In ablation procedure, the temperature that melts of each electrode is presented on radiofrequency melting instrument in real time, as occurs excess Temperature, can end melting of this electrode, avoids excessively melting.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, do not departing under the early stage of the technology of the present invention principle; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (10)

1. the multipole ablation catheter of renal artery, comprises and it is characterized in that ablation catheter and the function handle of adjustable bent catheter sheath, adjustable diameter:
Described adjustable bent catheter sheath one end is fixed on the crooked control piece of function handle, controls the free bend of the other end by crooked control piece;
The skeleton that comprises at least two adjustable diameters of the ablation catheter of described adjustable diameter, on every skeleton straight section, fix at least one electrode, each electrode is connected with the ablation apparatus interface of function handle by wire, ablation catheter one end is fixed in described skeleton one end, the other end be fixed on can the skeleton connector with respect to ablation catheter activity on, skeleton control valve one end of described ablation catheter is connected with head end part through skeleton connector, the other end is fixed on the skeleton control piece of function handle, and described skeleton control piece can be controlled the diameter adjustment of described skeleton;
One end of the ablation catheter of described adjustable diameter is fixed on the ablation catheter extension and contraction control part of function handle, and the skeleton that can realize described ablation catheter by ablation catheter extension and contraction control part passes in and out described adjustable bent catheter sheath.
2. the multipole ablation catheter of renal artery as claimed in claim 1, the framing structure that it is characterized in that described adjustable diameter is straight section in the middle of being, two ends are contracted to the Rugby structure of a bit.
3. the multipole ablation catheter of renal artery as claimed in claim 2, the skeleton that it is characterized in that described adjustable diameter is 2~8.
4. the multipole ablation catheter of renal artery as claimed in claim 3, is characterized in that the skeleton straight section length of described adjustable diameter is 10~30mm.
5. the multipole ablation catheter of renal artery as claimed in claim 4, is characterized in that being fixed with 1~3 electrode on the straight section of skeleton of described adjustable diameter.
6. the multipole ablation catheter of renal artery as claimed in claim 1, is characterized in that the diameter of skeleton straight section from described adjustable bent catheter sheath discharges of described adjustable diameter is 3~10mm.
7. the multipole ablation catheter of renal artery as claimed in claim 1, is characterized in that described adjustable bending pipe sheath is double lumen structure, a logical ablation catheter of tube chamber, a logical traction fiber of tube chamber.
8. the multipole ablation catheter of renal artery as claimed in claim 7, is characterized in that the traction fiber one end in described adjustable bending pipe sheath is fixed on the end of adjustable bending pipe sheath, and the other end is fixed on the traction fiber fixture of function handle.
9. the multipole ablation catheter of renal artery as claimed in claim 1, it is characterized in that being provided with on described function handle ablation apparatus interface, each electrode is connected with described ablation apparatus interface by wire, described ablation apparatus interface can be realized and being connected of radio-frequency (RF) ablation instrument by connecting line, by transmission of radio-frequency energy to each electrode.
10. the multipole ablation catheter of renal artery as claimed in claim 1, it is characterized in that described electrode is connected with temperature sensor, by wire, be connected with described ablation apparatus interface, described ablation apparatus interface can be realized and being connected of radio-frequency (RF) ablation instrument by connecting line, and the temperature signal of each electrode is presented on radio-frequency (RF) ablation instrument.
CN201210233475.6A 2012-07-07 2012-07-07 Multi-electrode renal artery ablation catheter Active CN103519882B (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105193498A (en) * 2015-09-18 2015-12-30 先健科技(深圳)有限公司 Ablation catheter device
CN106901831A (en) * 2017-03-23 2017-06-30 深圳市惠泰医疗器械有限公司 The arteria renalis stimulates ablating electrode conduit
CN107440786A (en) * 2016-06-01 2017-12-08 四川锦江电子科技有限公司 A kind of ablation catheter and ablating device of reconfigurable section
CN108784825A (en) * 2017-05-05 2018-11-13 上海安通医疗科技有限公司 A kind of electrode adherence method of detection radio frequency ablation catheter
CN114271928A (en) * 2021-12-26 2022-04-05 上海安通医疗科技有限公司 Combined ablation catheter for radial artery
CN114424971A (en) * 2022-01-26 2022-05-03 上海鑫律通生命科技有限公司 Spline basket ablation catheter capable of being bent in two directions
CN114557767A (en) * 2022-02-10 2022-05-31 上海安通医疗科技有限公司 Ablation catheter
WO2022143988A1 (en) * 2020-12-31 2022-07-07 杭州德诺电生理医疗科技有限公司 Ablation device and ablation system

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105193498A (en) * 2015-09-18 2015-12-30 先健科技(深圳)有限公司 Ablation catheter device
CN107440786A (en) * 2016-06-01 2017-12-08 四川锦江电子科技有限公司 A kind of ablation catheter and ablating device of reconfigurable section
CN106901831A (en) * 2017-03-23 2017-06-30 深圳市惠泰医疗器械有限公司 The arteria renalis stimulates ablating electrode conduit
CN108784825A (en) * 2017-05-05 2018-11-13 上海安通医疗科技有限公司 A kind of electrode adherence method of detection radio frequency ablation catheter
WO2022143988A1 (en) * 2020-12-31 2022-07-07 杭州德诺电生理医疗科技有限公司 Ablation device and ablation system
CN114271928A (en) * 2021-12-26 2022-04-05 上海安通医疗科技有限公司 Combined ablation catheter for radial artery
CN114424971A (en) * 2022-01-26 2022-05-03 上海鑫律通生命科技有限公司 Spline basket ablation catheter capable of being bent in two directions
CN114557767A (en) * 2022-02-10 2022-05-31 上海安通医疗科技有限公司 Ablation catheter

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