CN103705224A - Arteriosclerosis measuring device - Google Patents
Arteriosclerosis measuring device Download PDFInfo
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- CN103705224A CN103705224A CN201310543836.1A CN201310543836A CN103705224A CN 103705224 A CN103705224 A CN 103705224A CN 201310543836 A CN201310543836 A CN 201310543836A CN 103705224 A CN103705224 A CN 103705224A
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Abstract
The invention provides an arteriosclerosis measuring device. A first cuff is tied to one upper limb part of a to-be-measured person. A second cuff is tied to one lower limb of the to-be-measured person. A microprocessor is used to obtain pressure signals, pulse signals or pressure signals and pulse signals in the first inflatable cuff and the second inflatable cuff through a first pressure sensor and a second pressure sensor. The pulse signal time difference is measured by the microprocessor. The arteriosclerosis measuring device has the advantages that the pulse signal transmission time difference can be measured reliably, accurately and fast, the device is simple to operate, fast in measuring and low in cost, and the reliability by using the pulse signal time difference measuring result as the judging foundation can be guaranteed.
Description
Technical field
The present invention relates to a kind of arteriosclerosis measuring device.
Background technology
Arteriosclerosis can make that ductus arteriosus wall thickens, hardening, follows the string, luminal stenosis.Arteriosclerosis is with age and the angiopathy that occurs, and its rule normally occurs at adolescence, increases the weight of period, falls ill to person in middle and old age.Male is many compared with women, and primary disease increases gradually in China in recent years, becomes one of old people's main cause of death.In recent years, due to the ossify this positive correlation of degree of pulse wave transmission speed PWV and tremulous pulse, add its measuring method simple and easy to do and there is no a wound, so, be widely used and be used as assessing an index of arteriosclerosis degree.
PWV, refers to the spread speed of pulse wave between two of Arterial system had both fixed a point, and according to Moens-Korteweg equation, PWV is directly proportional to the square root of coefficient of elasticity, and due to the attenuating of arterial elasticity, pulse wave has been accelerated in the spread speed of Arterial system.In normal situation, PWV increases along with the increase at age.Generally PWV normal value is: 45 years old following adult's <9 meter per second (m/s); 45 years old above <10m/s.PWV is higher, prompting
arteriosclerosisdegree is heavier.
In existing measuring device, due to pulse wave be subject to the impact of measurement system noise and pulse wave signal itself very faint, cause the measurement accuracy of pulse signal transmission time difference undesirable, affected the measurement result of pulse wave transmission speed as judging basic reliability.
The problems referred to above are the problems that should pay attention to and solve in the measuring process of pulse signal transmission time difference.
Summary of the invention
The object of this invention is to provide a kind of arteriosclerosis measuring device solves in existing measuring device, due to pulse wave be subject to the impact of measurement system noise and pulse wave signal itself very faint, cause the measurement accuracy of pulse signal transmission time difference undesirable, affected the measurement result of pulse wave transmission speed as the problem of judging basic reliability.
Technical solution of the present invention is:
An arteriosclerosis measuring device, comprising:
The first cuff for colligation at upper limb position;
The second cuff for colligation at lower limb position;
The first pressure transducer being connected with described the first cuff;
The second pressure transducer being connected with described the second cuff;
Be used for one or more than one air pump that described the first cuff and/or the second cuff are inflated;
The first gas bleeder valve that described the first cuff is lost heart;
The second gas bleeder valve that described the second cuff is lost heart;
Microprocessor, be used for controlling described air pump, gas bleeder valve, for the treatment of the first cuff obtaining by the first pressure transducer, the second pressure transducer respectively, pressure signal and/or the pulse signal in the second cuff, described microprocessor is carried out the arteriosclerosis measuring process comprising the following steps:
A, use the first air pump, the first pressure transducer and the first gas bleeder valve in described the first cuff, air pump or an above air pump, measure described artery of upper extremity blood pressure, and the pulse signal amplitude in first cuff of sening as an envoy to of simultaneously measuring reaches maximum cuff pressure P1A; Use the first air pump, the second pressure transducer and the second gas bleeder valve in described the second cuff, an air pump or an above air pump, measure described artery of lower extremity blood pressure, and measure and make pulse signal amplitude in the second cuff reach maximum cuff pressure P2A simultaneously;
B, by the first air pump in the above air pump of a described air pump or, described the first cuff is pressurized to a force value in P1A or the upper next given range of P1A, by the second air pump in a described air pump or an above air pump, the second cuff is pressurized to a force value in P2A or the upper next given range of P2A, then by described the first pressure transducer and the second pressure transducer, measures respectively three or three above pulse signals of described the first cuff and the second cuff simultaneously;
C, calculate the time difference between in described the second cuff three or three above pulse signals and described the first cuff three or three pulse signals above, with this, determine measured's arteriosclerosis degree.
Preferably, the upper next given range of described P1A is P1A ± 10mmHg, and the upper next given range of described P2A is P2A ± 10mmHg.
Preferably, calculate a given number in eight to 16 in the pulse signal of a given number in eight to 16 in described the second cuff and described the first cuff pulse signal between time difference, with this, determine measured's arteriosclerosis degree.
Preferably, by calculating the time difference between definite described pulse signal of peaked time of correlation function between in described the second cuff three or three above pulse signals and described the first cuff three or three above pulse signals.
Preferably, described measured's arteriosclerosis degree is an index, the described index value of calculation that to be the second cuff lashing location obtain divided by the time difference between described pulse signal to the difference of the distance of heart to the distance of heart and the first cuff lashing location.
Preferably, the method of calculating the time difference between described pulse signal is: the wave function y (t) that establishes n pulse signal C2A of described the second cuff, 0≤t≤T, the wave function of the n of described the first cuff pulse signal C1A is x (t), 0≤t≤T, the correlation function R (τ) that calculates described y (t) and x (t), computing formula is
, more corresponding τ-value when calculating described correlation function R (τ) and getting maximum, establishing described τ-value is τ 0, τ 0 is exactly measured's pulse signal transmission time difference.
Preferably, the method of calculating the time difference between described pulse signal is: the pulse signal wave function of establishing n pulse signal C2A of described the second cuff is respectively q1 (t), q2 (t) ... qn (t), and 0≤t≤T, the pulse signal wave function of the n of described the first cuff pulse signal C1A is p1 (t), p2 (t) ... pn (t), and 0≤t≤T, calculate respectively the correlation function Ri (τ) of qi (t) and pi (t), 0≤i≤n and be integer wherein, computing formula is
corresponding τ-value when calculating respectively more described n correlation function R1 (τ) and getting maximum to Rn (τ), if described τ-value is respectively τ 1, τ 2... τ n, then calculate the meansigma methods that described τ 1 arrives τ n, described meansigma methods is exactly measured's pulse signal transmission time difference.
Preferably, use pressurization measurement method or decompression measurement method, for the air pressure P1 (t) and the pulse signal A1 (t) that detect described the first cuff by described the first pressure transducer, when tri-continuous pulse signal A1 (t1) constantly of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) < A1 (t2) > A1 (t3) and is related to, t2 constantly corresponding air pressure be that target is pressed P1A.
Preferably, use pressurization measurement method or decompression measurement method, for the air pressure P2 (t) and the pulse signal A2 (t) that detect described the second cuff by described the second pressure transducer, when tri-continuous pulse signal A2 (t21) constantly of t21, t22 and t23 being detected, A2 (t22), when A2 (t23) meets A2 (t21) < A2 (t22) > A2 (t23) and is related to, t22 constantly corresponding air pressure be that target is pressed P2A.
The invention has the beneficial effects as follows: a kind of arteriosclerosis measuring device of the present invention, can measure reliably, accurately and quickly pulse signal transmission time difference, have simple to operate, measure fast and the low advantage of cost, can guarantee that the measurement result of pulse signal transmission time difference is as judging basic reliability.
Accompanying drawing explanation
Fig. 1 is the structure explanation block diagram of the embodiment of the present invention one;
Fig. 2 is the structure explanation block diagram of the embodiment of the present invention two;
Fig. 3 is the structure explanation block diagram of the embodiment of the present invention three;
Fig. 4 is the structural representation of the embodiment of the present invention;
Fig. 5 is decompression measurement method the first cuff and the second cuff adds, decompression and pulse signal sequential chart;
Fig. 6 is pulse signal enlarged diagram in Fig. 5;
Fig. 7 is pressurization measurement method the first cuff and the second cuff adds, decompression and pulse signal sequential chart;
Fig. 8 is pulse signal enlarged diagram in Fig. 7.
Wherein: 1-the first cuff, 2-the second cuff, 3-main frame, 4-the first trachea, 5-the second trachea;
Pressure signal or pulse signal curve when C1-the first cuff is inflated or loses heart, pressure signal or pulse signal curve when C2-the second cuff is inflated or loses heart.
The specific embodiment
Below in conjunction with accompanying drawing, describe the preferred embodiments of the present invention in detail.
As shown in Figure 1, Figure 2 or shown in Fig. 3, a kind of arteriosclerosis measuring device, comprises main frame 3, and the first cuff 1 being connected with main frame 3 respectively and the second cuff 2.The first cuff 1 is a upper arm cuff, for being bundled in a tested upper limb, can block the blood flow of tested artery of upper extremity after inflation completely, and is connected with the upper limb air bag interface of main frame 3 by the first trachea 4.The second cuff 2 is ankle cufves, for being bundled in tested lower limb, can block the blood flow of tested artery of lower extremity after inflation completely, and is connected with the lower limb air bag interface of main frame 3 by the second trachea 5.The first pressure transducer and the second pressure transducer join with the first cuff 1 and the second cuff 2 respectively by gas link, described the first pressure transducer and the second pressure transducer detect respectively force value and/or the pulse signal in the first cuff 1 and the second cuff 2 simultaneously, according to pulse signal and the atmospheric pressure value in described the first cuff 1 and the second cuff 2, determine systolic pressure and the diastolic pressure of tested artery of upper extremity, and the systolic pressure of artery of lower extremity and diastolic pressure.According to the systolic pressure of described artery of upper extremity, diastolic pressure and pulse signal, and the systolic pressure of described artery of lower extremity, diastolic pressure and pulse signal, determine measured's pulse signal transmission time difference.
Described main frame 3 comprises microprocessor, the human-computer interaction interface being connected with microprocessor respectively, the first pressure transducer, the second pressure transducer, gas charging system, the system of losing heart, and the upper limb air bag interface and the lower limb air bag interface that are connected with the second cuff 2 with the first cuff 1 respectively.Human-computer interaction interface is the human-computer interaction interface that comprises keyboard, display.Gas charging system comprises one or more than one air pump.Disappointing system comprises one or more than one gas bleeder valve.
Gas link is that one or more parts in trachea, joint, switch valve, three-way air valve form.
Embodiment mono-
For Fig. 1, there are successively following two kinds of steps:
The first step, for Fig. 5, has following steps:
1) the first cuff 1 and the second cuff 2 are bundled in respectively on a tested upper limb and tested lower limb, and are connected with lower limb air bag interface with the upper limb air bag interface on main frame 3 respectively with the second trachea 5 by the first trachea 4;
2) press the start key of main frame 3 keyboards, the first and second gas bleeder valves cut out, and the first and second air pumps are respectively to the first cuff 1 and the second cuff 2 inflations, and the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close the first and second air pumps, stop inflation;
4) control the first and second gas bleeder valves, respectively the first cuff 1 and the second cuff 2 are slowly lost heart, in the first cuff 1 and the slow disappointing process of the second cuff 2, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine respectively the systolic pressure of tested artery of upper extremity and tested artery of lower extremity;
5) continue the first cuff 1 and the second cuff 2 slowly to lose heart, in the first cuff 1 and the slow disappointing process of the second cuff 2, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, a target of definite tested artery of upper extremity and tested artery of lower extremity is pressed P1A and P2A respectively, determines the following 5-1 of method difference of this target pressure P1A and P2A) and 5-2):
5-1) for detect air pressure and the pulse signal of the first cuff 1 by the first pressure transducer, waveform is as shown in the P1 of Fig. 5 (t) and A1 (t), when tri-continuous pulse signal A1 (t1) constantly of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) < A1 (t2) > A1 (t3) and is related to, t2 constantly corresponding air pressure be that target is pressed P1A;
5-2) for detect air pressure and the pulse signal of the second cuff 2 by the second pressure transducer, waveform is as shown in the P2 of Fig. 5 (t) and A2 (t), when tri-continuous pulse signal A2 (t21) constantly of t21, t22 and t23 being detected, A2 (t22), when A21 (t23) meets A2 (t21) < A2 (t22) > A2 (t23) and is related to, t22 constantly corresponding air pressure be that target is pressed P2A;
6) continue the first cuff 1 and the second cuff 2 slowly to lose heart, in the first cuff 1 and the slow disappointing process of the second cuff 2, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine respectively the diastolic pressure of tested artery of upper extremity and tested artery of lower extremity;
7) air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first and second gas bleeder valves, open the first and second air pumps, respectively to the first cuff 1 and the second cuff 2 pressurizations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close the first and second air pumps, stop pressurization;
7-2) open the first and second gas bleeder valves, give respectively the first cuff 1 and the second cuff 2 venting, until discharge, then wait for a period of time, close again the first and second gas bleeder valves, open the first and second air pumps, respectively to the first cuff 1 and the second cuff 2 pressurizations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close the first and second air pumps, stop pressurization;
8) by the first pressure transducer and the second pressure transducer, detect respectively three or three above pulse signals in the first cuff 1 and the second cuff 2, according to the pulse signal of described the first cuff 1 and the second cuff 2, determine measured's pulse signal transmission time difference.The method of determining measured's pulse signal transmission time difference has two kinds, respectively following 8-1) and 8-2):
8-1) by the first pressure transducer and the second pressure transducer, detect respectively in the first cuff 1 and the second cuff 2 pulse signal of a given number in eight to 16, calculate the pulse signal of the described given number in the second cuff 2 and the described given number in the first cuff 1 pulse signal between time difference, for example given number is 12, its waveform is as shown in C2A and C1A in Fig. 6, first calculate d1=t26-t6, d2=t27-t7, d3=t28-t8, d4=t29-t9, d5=t30-t10, d6=t31-t11, d7=t32-t12, d8=t33-t13, d9=t34-t14, d10=t35-t15, d11=t36-t16, d12=t37-t17, calculate again the meansigma methods of d1 ~ d12, described meansigma methods is exactly measured's pulse signal transmission time difference,
8-2) by the first pressure transducer and the second pressure transducer, detect respectively three or three above pulse signals in the first cuff 1 and the second cuff 2, the peaked time of correlation function between pulse signal of calculating described in pulse signal described in the second cuff 2 and the first cuff 1 is determined the time difference between described pulse signal, for example given number is 12, its waveform is as shown in C2A and C1A in Fig. 6, account form has two kinds, respectively following 8-2-1) and 8-2-2):
8-2-1) establish the wave function y (t) of 12 pulse signal C2A of the second cuff 2,0≤t≤T, the wave function of 12 pulse signal C1A of the first cuff 1 is x (t), 0≤t≤T, the correlation function R (τ) that calculates y (t) and x (t), computing formula is
, more corresponding τ-value when calculating described correlation function R (τ) and getting maximum, establishing described τ-value is τ 0, τ 0 is exactly measured's pulse signal transmission time difference;
The pulse signal wave function of 8-2-2) establishing 12 pulse signal C2A of the second cuff 2 is respectively q1 (t), q2 (t), q3 (t), q4 (t), q5 (t), q6 (t), q7 (t), q8 (t), q9 (t), q10 (t), q11 (t), q12 (t), and 0≤t≤T, the pulse signal wave function of 12 pulse signal C1A of the first cuff 1 is p1 (t), p2 (t), p3 (t), p4 (t), p5 (t), p6 (t), p7 (t), p8 (t), p9 (t), p10 (t), p11 (t), p12 (t), and 0≤t≤T, calculate respectively the correlation function Ri (τ) of qi (t) and pi (t), 0≤i≤T and be integer wherein, computing formula is
corresponding τ-value when calculating respectively again 12 correlation function R1 (τ) and getting maximum to R12 (τ), if described τ-value is respectively τ 1, τ 2, τ 3, τ 4, τ 5, τ 6, τ 7, τ 8, τ 9, τ 10, τ 11 and τ 12, the meansigma methods of calculating again τ 1 to τ 12, described meansigma methods is exactly measured's pulse signal transmission time difference,
9) open the first and second gas bleeder valves, lose heart to the first cuff 1 and the second cuff 2.
10) calculate an index of measured's arteriosclerosis degree, the described index value of calculation that to be the second cuff lashing location to the distance of heart and the first cuff lashing location obtain divided by described measured's pulse signal transmission time difference to the difference of the distance of heart.
The second step, for Fig. 7, has following steps:
1) the first cuff 1 and the second cuff 2 are bundled in respectively on a tested upper limb and tested lower limb, and are connected with lower limb air bag interface with the upper limb air bag interface on main frame 3 respectively with the second trachea 5 by the first trachea 4;
2) press the start key of main frame 3 keyboards, the first and second gas bleeder valves cut out, and the first and second air pumps are respectively to the first cuff 1 and the second cuff 2 inflations, and the air pressure of the first cuff 1 and the second cuff 2 slowly increases from zero;
3) in to the process of the first cuff 1 and the second cuff 2 slow pressurizations, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine respectively the diastolic pressure of tested artery of upper extremity and tested artery of lower extremity;
4) continue the first cuff 1 and the second cuff 2 slowly to pressurize, in the process of the first cuff 1 and the second cuff 2 slow pressurizations, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, a target of definite tested artery of upper extremity and tested artery of lower extremity is pressed P1A and P2A respectively, determines the following 4-1 of method difference of this target pressure P1A and P2A) and 4-2):
4-1) for detect air pressure and the pulse signal of the first cuff 1 by the first pressure transducer, waveform is as shown in the P1 of Fig. 6 (t) and A1 (t), when tri-continuous pulse signal A1 (t41) constantly of t41, t42 and t43 being detected, A1 (t42), when A1 (t43) meets A1 (t41) < A1 (t42) > A1 (t43) and is related to, t42 constantly corresponding air pressure be that target is pressed P1A;
4-2) for detect air pressure and the pulse signal of the second cuff 2 by the second pressure transducer, waveform is as shown in the P2 of Fig. 6 (t) and A2 (t), when tri-continuous pulse signal A2 (t61) constantly of t61, t62 and t63 being detected, A2 (t62), A2 (t63) meets A2 (t61) < A2 (t62) > A2 (t63), and t62 air pressure corresponding to the moment is that target is pressed P2A;
5) continue the first cuff 1 and the second cuff 2 slowly to pressurize, in the process of the first cuff 1 and the second cuff 2 slow pressurizations, by the first pressure transducer and the second pressure transducer, detect respectively air pressure and the pulse signal constantly changing in the first cuff 1 and the second cuff 2, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine respectively the systolic pressure of tested artery of upper extremity and tested artery of lower extremity;
6) air pressure of the first cuff 1 and the second cuff 2 reduced respectively or be increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, this step has two kinds of embodiments, respectively following 6-1) and 6-2):
6-1) open the first gas bleeder valve and the second gas bleeder valve, respectively the first cuff 1 and the second cuff 2 are lost heart, the air pressure of the first cuff 1 and the second cuff 2 is reduced to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is reduced to respectively to target and press P1A and P2A, close the first gas bleeder valve and the second gas bleeder valve, stop losing heart;
6-2) open the first gas bleeder valve and the second gas bleeder valve, give respectively the first cuff 1 and the second cuff 2 venting, until discharge, then wait for a period of time, close again the first gas bleeder valve and the second gas bleeder valve, open the first air pump and the second air pump, respectively to the first cuff 1 and the second cuff 2 pressurizations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close the first air pump and the second air pump, stop pressurization,
7) by the first pressure transducer and the second pressure transducer, detect respectively three or three above pulse signals in the first cuff 1 and the second cuff 2, according to the pulse signal of described the first cuff 1 and the second cuff 2, determine measured's pulse signal transmission time difference.The method of determining measured's pulse signal transmission time difference has two kinds, respectively following 7-1) and 7-2):
7-1) by the first pressure transducer and the second pressure transducer, detect respectively in the first cuff 1 and the second cuff 2 pulse signal of a given number in eight to 16, calculate the pulse signal of the described given number in the second cuff 2 and the described given number in the first cuff 1 pulse signal between time difference, for example given number is 12, its waveform is as shown in C2A and C1A in Fig. 8, first calculate d21=t66-t46, d22=t67-t47, d23=t68-t48, d24=t69-t49, d25=t70-t50, d26=t71-t51, d27=t72-t52, d28=t73-t53, d29=t74-t54, d30=t75-t55, d31=t76-t56, d32=t77-t57, calculate again the meansigma methods of d21 ~ d32, described meansigma methods is exactly measured's pulse signal transmission time difference,
7-2) by the first pressure transducer and the second pressure transducer, detect respectively three or three above pulse signals in the first cuff 1 and the second cuff 2, the peaked time of correlation function between pulse signal of calculating described in pulse signal described in the second cuff 2 and the first cuff 1 is determined the time difference between described pulse signal, for example given number is 12, its waveform is as shown in C2A and C1A in Fig. 8, account form has two kinds, respectively following 7-2-1) and 7-2-2):
7-2-1) establish the wave function y (t) of 12 pulse signal C2A of the second cuff 2,0≤t≤T, the wave function of 12 pulse signal C1A of the first cuff 1 is x (t), 0≤t≤T, the correlation function R (τ) that calculates y (t) and x (t), computing formula is
, more corresponding τ-value when calculating described correlation function R (τ) and getting maximum, establishing described τ-value is τ 0, τ 0 is exactly measured's pulse signal transmission time difference;
The pulse signal wave function of 7-2-2) establishing 12 pulse signal C2A of the second cuff 2 is respectively q1 (t), q2 (t), q3 (t), q4 (t), q5 (t), q6 (t), q7 (t), q8 (t), q9 (t), q10 (t), q11 (t), q12 (t), and 0≤t≤T, the pulse signal wave function of 12 pulse signal C1A of the first cuff 1 is p1 (t), p2 (t), p3 (t), p4 (t), p5 (t), p6 (t), p7 (t), p8 (t), p9 (t), p10 (t), p11 (t), p12 (t), and 0≤t≤T, calculate respectively the correlation function Ri (τ) of qi (t) and pi (t), 0≤i≤12 and be integer wherein, computing formula is
corresponding τ-value when calculating respectively again 12 correlation function R1 (τ) and getting maximum to R12 (τ), if described τ-value is respectively τ 1, τ 2, τ 3, τ 4, τ 5, τ 6, τ 7, τ 8, τ 9, τ 10, τ 11 and τ 12, the meansigma methods of calculating again τ 1 to τ 12, described meansigma methods is exactly measured's the pulse signal transmission time,
8) open gas bleeder valve 1 and gas bleeder valve 2, lose heart to the first cuff 1 and the second cuff 2.
9) calculate an index of measured's arteriosclerosis degree, the described index value of calculation that to be the second cuff lashing location to the distance of heart and the first cuff lashing location obtain divided by described measured's pulse signal transmission time difference to the difference of the distance of heart.
Embodiment bis-
As shown in Figure 2, there is following a kind of step:
For Fig. 5, only need to use the first step of Fig. 1, and by the step 2 in described step), 3) and 7) use respectively following steps 2), 3) and 7) replacement:
2) press the start key of main frame 3 keyboards, the first gas bleeder valve and the second gas bleeder valve are closed, timesharing is opened the first switch valve, closes second switch valve, opens air pump to the first cuff 1 inflation and is opened second switch valve, closes the first switch valve, opens air pump to the second cuff 2 inflations, and the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close air pump, stop inflation;
7) air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first gas bleeder valve and the second gas bleeder valve, timesharing is opened the first switch valve, closes second switch valve, opens air pump to the first cuff 1 inflation and is opened second switch valve, closes the first switch valve, opens air pump to the second cuff 2 inflations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close air pump, stop pressurization;
7-2) open the first gas bleeder valve and the second gas bleeder valve, give respectively the first cuff 1 and the second cuff 2 venting, until discharge, then wait for a period of time, close again the first gas bleeder valve and the second gas bleeder valve, the first switch valve is opened in timesharing, close second switch valve, open air pump to the first cuff 1 inflation and open second switch valve, close the first switch valve, open air pump to the second cuff 2 inflations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close air pump, stop pressurization.
Embodiment tri-
As shown in Figure 3, there is following a kind of step:
For Fig. 5, only need to use the first step of Fig. 1, and by the step 2 in described step), 3) and 7) use respectively following steps 2), 3) and 7) replacement:
2) press the start key of main frame 3 keyboards, the first gas bleeder valve and the second gas bleeder valve are closed, timesharing is connected three-way air valve air pump and the first cuff 1, is opened air pump and connect air pump and the second cuff 2, open air pump to the second cuff 2 inflations to the first cuff 1 inflation with by three-way air valve, and the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close air pump, stop inflation;
7) air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first gas bleeder valve and the second gas bleeder valve, timesharing is connected three-way air valve air pump and the first cuff 1, is opened air pump and connect air pump and the second cuff 2, open air pump to the second cuff 2 inflations to the first cuff 1 inflation with by three-way air valve, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close air pump, stop pressurization;
7-2) open the first gas bleeder valve and the second gas bleeder valve, give respectively the first cuff 1 and the second cuff 2 venting, until discharge, then wait for a period of time, close again the first gas bleeder valve and the second gas bleeder valve, timesharing is connected air pump and the first cuff 1 by three-way air valve, open air pump to the first cuff 1 inflation and three-way air valve is connected to air pump and the second cuff 2, open air pump to the second cuff 2 inflations, the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target presses within the scope of P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, for example the air pressure of the first cuff 1 and the second cuff 2 is increased to respectively to target and presses P1A and P2A, close air pump, stop pressurization.
Above content is further to convert in detail brightly in conjunction with concrete preferred implementation is made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention; make without departing from the inventive concept of the premise some alternative or obvious modification that are equal to; and performance or purposes identical, all should be considered as belonging to the present invention by the definite patent protection model of submitted to claims with.
Claims (9)
1. an arteriosclerosis measuring device, is characterized in that, comprising:
The first cuff for colligation at upper limb position;
The second cuff for colligation at lower limb position;
The first pressure transducer being connected with described the first cuff;
The second pressure transducer being connected with described the second cuff;
For or the more than one air pump that described the first cuff and/or the second cuff are inflated;
The first gas bleeder valve that described the first cuff is lost heart;
The second gas bleeder valve that described the second cuff is lost heart;
Microprocessor, be used for controlling described air pump, gas bleeder valve, for the treatment of the first cuff obtaining by the first pressure transducer, the second pressure transducer respectively, pressure signal and/or the pulse signal in the second cuff, described microprocessor is carried out the arteriosclerosis measuring process comprising the following steps:
The first air pump, the first pressure transducer and the first gas bleeder valve in A, use the first cuff, an air pump or an above air pump, measure described artery of upper extremity blood pressure, and the pulse signal amplitude in first cuff of sening as an envoy to of simultaneously measuring reaches maximum cuff pressure P1A; Use the first air pump, the second pressure transducer and the second gas bleeder valve in the second cuff, an air pump or an above air pump, measure described artery of lower extremity blood pressure, and measure and make pulse signal amplitude in the second cuff reach maximum cuff pressure P2A simultaneously;
B, by the first air pump in the above air pump of a described air pump or, described the first cuff is pressurized to a force value in P1A or the upper next given range of P1A, by the second air pump in a described air pump or an above air pump, the second cuff is pressurized to a force value in P2A or the upper next given range of P2A, then by described the first pressure transducer and the second pressure transducer, measures respectively three or three above pulse signals in described the first cuff and the second cuff simultaneously;
C, calculate the time difference between in described the second cuff three or three above pulse signals and described the first cuff three or three pulse signals above, with this, determine measured's arteriosclerosis degree.
2. arteriosclerosis measuring device as claimed in claim 1, is characterized in that: the upper next given range of described P1A is P1A ± 10mmHg, and the upper next given range of described P2A is P2A ± 10mmHg.
3. arteriosclerosis measuring device as claimed in claim 1, it is characterized in that: calculate a given number in eight to 16 in the pulse signal of a given number in eight to 16 in described the second cuff and described the first cuff pulse signal between time difference, with this, determine measured's arteriosclerosis degree.
4. the arteriosclerosis measuring device as described in claim 1-3 any one, is characterized in that: by calculating the time difference between definite described pulse signal of peaked time of correlation function between in described the second cuff three or three above pulse signals and described the first cuff three or three above pulse signals.
5. the arteriosclerosis measuring device as described in claim 1-3 any one, it is characterized in that: described measured's arteriosclerosis degree is an index the described index value of calculation that to be the second cuff lashing location obtain divided by the time difference between described pulse signal to the difference of the distance of heart to the distance of heart and the first cuff lashing location.
6. the method for calculating pulse signal transmission time difference as claimed in claim 4, is characterized in that, described computational methods are specially:
If the wave function y (t) of the n of described the second cuff pulse signal C2A, 0≤t≤T, the wave function of the n of described the first cuff pulse signal C1A is x (t), 0≤t≤T, the correlation function R (τ) that calculates described y (t) and x (t), computing formula is
, more corresponding τ-value when calculating described correlation function R (τ) and getting maximum, establishing described τ-value is τ 0, τ 0 is exactly measured's pulse signal transmission time difference.
7. the method for calculating pulse signal transmission time difference as claimed in claim 4, is characterized in that, described computational methods are specially:
If the pulse signal wave function of the n of described the second cuff pulse signal C2A is respectively q1 (t), q2 (t) ... qn (t), and 0≤t≤T, the pulse signal wave function of the n of described the first cuff pulse signal C1A is p1 (t), p2 (t) ... pn (t), and 0≤t≤T, calculates respectively the correlation function Ri (τ) of described qi (t) and pi (t), 0≤i≤n and be integer wherein, computing formula is
corresponding τ-value when calculating respectively more described n correlation function R1 (τ) and getting maximum to Rn (τ), if described τ-value is respectively τ 1, τ 2... τ n, then calculate the meansigma methods that described τ 1 arrives τ n, described meansigma methods is exactly measured's pulse signal transmission time difference.
8. the measuring method of the pulse signal transmission time difference as described in claim 1-3 any one, it is characterized in that: use pressurization measurement method or decompression measurement method, for the air pressure P1 (t) and the pulse signal A1 (t) that detect described the first cuff by described the first pressure transducer, when tri-continuous pulse signal A1 (t1) constantly of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) < A1 (t2) > A1 (t3) and is related to, t2 constantly corresponding air pressure be that target is pressed P1A.
9. the measuring method of the pulse signal transmission time difference as described in claim 1-3 any one, it is characterized in that: use pressurization measurement method or decompression measurement method, for the air pressure P2 (t) and the pulse signal A2 (t) that detect described the second cuff by described the second pressure transducer, when tri-continuous pulse signal A2 (t21) constantly of t21, t22 and t23 being detected, A2 (t22), when A2 (t23) meets A2 (t21) < A2 (t22) > A2 (t23) and is related to, t22 constantly corresponding air pressure be that target is pressed P2A.
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| CN106371564A (en) * | 2015-08-28 | 2017-02-01 | 北京智谷睿拓技术服务有限公司 | Input information determination method and equipment |
| CN107411724A (en) * | 2017-07-27 | 2017-12-01 | 悦享趋势科技（北京）有限责任公司 | Artery sclerosis measuring instrument and artery sclerosis measuring method |
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