CN103705224B - Arteriosclerosis measuring device - Google Patents

Arteriosclerosis measuring device Download PDF

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Publication number
CN103705224B
CN103705224B CN201310543836.1A CN201310543836A CN103705224B CN 103705224 B CN103705224 B CN 103705224B CN 201310543836 A CN201310543836 A CN 201310543836A CN 103705224 B CN103705224 B CN 103705224B
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cuff
pulse signal
pressure
time difference
pressure transducer
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CN103705224A (en
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陈云权
周萌
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Yasunao Medical Technology (danyang) Co Ltd
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Yasunao Medical Technology (danyang) Co Ltd
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Abstract

The invention provides a kind of arteriosclerosis measuring device, by the first cuff colligation at measured one upper limb position, by the second cuff colligation at measured one lower extremity; Use microprocessor, process by pressure signal, pulse signal or the pressure signal in first and second inflatable cufves of first and second pressure transducer acquisition and pulse signal, drawn by microprocessor and measure pulse signal time difference: this kind of arteriosclerosis measuring device, reliably, accurately and quickly can measure pulse signal transmission time difference, there is simple to operate, that measurement is quick and cost is low advantage, can ensure that the measurement result of pulse signal transmission time difference is as the reliability judging basis.

Description

Arteriosclerosis measuring device
Technical field
The present invention relates to a kind of arteriosclerosis measuring device.
Background technology
Arteriosclerosis can make ductus arteriosus wall thicken, hardening, to follow the string, luminal stenosis.Arteriosclerosis be with age and occur angiopathy, its rule normally adolescence occur, increase the weight of period to person in middle and old age, fall ill.Male is many compared with women, and primary disease increases gradually in China in recent years, becomes one of old people's main cause of death.In recent years, due to this positive correlation of pulse wave transmission speed PWV and tremulous pulse degree of ossifing, it is simple and easy to do and do not have wound to add its measuring method, so, be widely used and be used as assessing an index of Degree of arteriosclerosis.
PWV, refer to the spread speed of pulse wave between two of Arterial system had both fixed a point, according to Moens-Korteweg equation, PWV is directly proportional to the square root of coefficient of elasticity, and due to the attenuating of arterial elasticity, pulse wave accelerates in the spread speed of Arterial system.In normal situation, PWV increases along with the increase at age.Generally PWV normal value is: less than 45 years old adult <9 meter per second (m/s); More than 45 years old <10m/s.PWV is higher, prompting arteriosclerosisdegree is heavier.
In existing measuring device, due to pulse wave by the impact of measurement system noise and pulse wave signal itself very faint, cause the measurement accuracy of pulse signal transmission time difference undesirable, have impact on the measurement result of pulse wave transmission speed as the reliability judging basis.
The problems referred to above should be paid attention in the measuring process of pulse signal transmission time difference and the problem solved.
Summary of the invention
The object of this invention is to provide a kind of arteriosclerosis measuring device solves in existing measuring device, due to pulse wave by the impact of measurement system noise and pulse wave signal itself very faint, cause the measurement accuracy of pulse signal transmission time difference undesirable, have impact on the measurement result of pulse wave transmission speed as the problem judging basic reliability.
Technical solution of the present invention is:
A kind of arteriosclerosis measuring device, comprising:
For first cuff of colligation at upper limb position;
For second cuff of colligation at lower extremity;
The first pressure transducer be connected with described first cuff;
The second pressure transducer be connected with described second cuff;
The more than one air pump inflated is carried out for described first cuff and/or the second cuff;
To the first gas bleeder valve that described first cuff loses heart;
To the second gas bleeder valve that described second cuff loses heart;
Microprocessor, for controlling described air pump, gas bleeder valve, for the treatment of the pressure signal in the first cuff obtained respectively by the first pressure transducer, the second pressure transducer, the second cuff and/or pulse signal, described microprocessor performs the arteriosclerosis measuring process comprised the following steps:
A, use described first cuff, air pump, the first pressure transducer and the first gas bleeder valve, measure described artery of upper extremity blood pressure, and pulse signal amplitude in the first cuff of sening as an envoy to of simultaneously measuring reaches maximum cuff pressure P1A; Use described second cuff, air pump, the second pressure transducer and the second gas bleeder valve, measure described artery of lower extremity blood pressure, and measurement makes pulse signal amplitude in the second cuff reach maximum cuff pressure P2A simultaneously;
B, by described air pump, a force value on P1A or P1A in next given range is pressurized to described first cuff, by described air pump, a force value on P2A or P2A in next given range is pressurized to the second cuff, is then measured the pulse signal of more than three of described first cuff and the second cuff by described first pressure transducer and the second pressure transducer simultaneously respectively;
C, calculate time difference between the pulse signal of more than three in described second cuff and the pulse signal of more than three in described first cuff, determine measured's Degree of arteriosclerosis with this.
Preferably, on described P1A, next given range is P1A ± 10mmHg, and on described P2A, next given range is P2A ± 10mmHg.
Preferably, calculate a given number in eight to ten six in the pulse signal of a given number in eight to ten six in described second cuff and described first cuff pulse signal between time difference, determine measured's Degree of arteriosclerosis with this.
Preferably, the time by calculating correlation function maximum between the pulse signal of more than three in described second cuff and the pulse signal of more than three in described first cuff determines the time difference between described pulse signal.
Preferably, described measured's Degree of arteriosclerosis is an index, the described index value of calculation that to be the second cuff lashing location obtain divided by the time difference between described pulse signal to the distance of heart and the first cuff lashing location to the difference of the distance of heart.
Preferably, the method calculating the time difference between described pulse signal is: wave function y (t) establishing n pulse signal C2A of described second cuff, 0≤t≤T, the wave function of n pulse signal C1A of described first cuff is x (t), 0≤t≤T, calculate the correlation function R (τ) of described y (t) and x (t), computing formula is calculate τ-value corresponding when described correlation function R (τ) gets maximum again, if described τ-value is τ 0, then τ 0 is exactly the pulse signal transmission time difference of measured.
Preferably, the method calculating the time difference between described pulse signal is: establish the pulse signal wave function of n pulse signal C2A of described second cuff to be respectively q1 (t), q2 (t) ... qn (t), and 0≤t≤T, the pulse signal wave function of n pulse signal C1A of described first cuff is p1 (t), p2 (t) ... pn (t), and 0≤t≤T, calculate the correlation function Ri (τ) of qi (t) and pi (t) respectively, wherein 0≤i≤n and be integer, computing formula is calculate τ-value corresponding when described n correlation function R1 (τ) gets maximum to Rn (τ) more respectively, if described τ-value is respectively τ 1, τ 2... τ n, calculate the meansigma methods of described τ 1 to τ n again, described meansigma methods is exactly the pulse signal transmission time difference of measured.
Preferably, use pressurization measurement method or decompression measurement method, for air pressure P1 (t) and pulse signal A1 (t) that are detected described first cuff by described first pressure transducer, when the pulse signal A1 (t1) in tri-continuous moment of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) <A1 (t2) >A1 (t3) relation, then the air pressure that the t2 moment is corresponding is target pressure P1A.
Preferably, use pressurization measurement method or decompression measurement method, for air pressure P2 (t) and pulse signal A2 (t) that are detected described second cuff by described second pressure transducer, when the pulse signal A2 (t21) in tri-continuous moment of t21, t22 and t23 being detected, A2 (t22), when A2 (t23) meets A2 (t21) <A2 (t22) >A2 (t23) relation, then the air pressure that the t22 moment is corresponding is target pressure P2A.
The invention has the beneficial effects as follows: a kind of arteriosclerosis measuring device of the present invention, reliably, accurately and quickly can measure pulse signal transmission time difference, there is simple to operate, that measurement is quick and cost is low advantage, can ensure that the measurement result of pulse signal transmission time difference is as the reliability judging basis.
Accompanying drawing explanation
Fig. 1 is that the structure of the embodiment of the present invention one illustrates block diagram;
Fig. 2 is that the structure of the embodiment of the present invention two illustrates block diagram;
Fig. 3 is that the structure of the embodiment of the present invention three illustrates block diagram;
Fig. 4 is the structural representation of the embodiment of the present invention;
Fig. 5 is that decompression measurement method first cuff and the second cuff add, reduce pressure and pulse signal sequential chart;
Fig. 6 is pulse signal enlarged diagram in Fig. 5;
Fig. 7 is that pressurization measurement method first cuff and the second cuff add, reduce pressure and pulse signal sequential chart;
Fig. 8 is pulse signal enlarged diagram in Fig. 7.
Wherein: 1-first cuff, 2-second cuff, 3-main frame, 4-first trachea, 5-second trachea; C1-first cuff inflation or disappointing time pressure signal or pulse signal curve, C2-second cuff inflation or disappointing time pressure signal or pulse signal curve.
Detailed description of the invention
The preferred embodiments of the present invention are described in detail below in conjunction with accompanying drawing.
As shown in Figure 1, Figure 2 or shown in Fig. 3, a kind of arteriosclerosis measuring device, comprises main frame 3, and the first cuff 1 and the second cuff 2 be connected with main frame 3 respectively.First cuff 1 is a upper arm cuff, for being bundled in a tested upper limb, can block the blood flow of tested artery of upper extremity after inflation completely, and is connected with the upper limb balloon interface of main frame 3 by the first trachea 4.Second cuff 2 is ankle cufves, for being bundled in tested lower limb, can block the blood flow of tested artery of lower extremity after inflation completely, and is connected with the lower limb balloon interface of main frame 3 by the second trachea 5.First pressure transducer and the second pressure transducer are connected with the first cuff 1 and the second cuff 2 respectively by gas connection part, described first pressure transducer and the second pressure transducer detect force value in the first cuff 1 and the second cuff 2 and/or pulse signal simultaneously respectively, according to the pulse signal in described first cuff 1 and the second cuff 2 and atmospheric pressure value, determine systolic pressure and the diastolic pressure of tested artery of upper extremity, and the systolic pressure of artery of lower extremity and diastolic pressure.According to the systolic pressure of described artery of upper extremity, diastolic pressure and pulse signal, and the systolic pressure of described artery of lower extremity, diastolic pressure and pulse signal, determine the pulse signal transmission time difference of measured.
Described main frame 3 comprises microprocessor, the human-computer interaction interface be connected with microprocessor respectively, the first pressure transducer, the second pressure transducer, gas charging system, system of losing heart, and the upper limb balloon interface be connected with the first cuff 1 and the second cuff 2 respectively and lower limb balloon interface.Human-computer interaction interface is the human-computer interaction interface comprising keyboard, display.Gas charging system comprises more than one air pump.Disappointing system comprises more than one gas bleeder valve.
Gas connection part is made up of one or more parts in trachea, joint, switch valve, three-way air valve.
Embodiment one
For Fig. 1, there are following two kinds of steps successively:
The first step, for Fig. 5, has following steps:
1) the first cuff 1 and the second cuff 2 are bundled on a tested upper limb and tested lower limb respectively, and are connected with the upper limb balloon interface on main frame 3 and lower limb balloon interface respectively with the second trachea 5 by the first trachea 4;
2) press the start key of main frame 3 keyboard, the first and second gas bleeder valves cut out, and the first and second air pumps are inflated respectively to the first cuff 1 and the second cuff 2, and the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close the first and second air pumps, stop inflation;
4) the first and second gas bleeder valves are controlled, respectively the first cuff 1 and the second cuff 2 are slowly lost heart, in the process that the first cuff 1 and the second cuff 2 slowly lose heart, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine the systolic pressure of tested artery of upper extremity and tested artery of lower extremity respectively;
5) continue slowly to lose heart to the first cuff 1 and the second cuff 2, in the process that the first cuff 1 and the second cuff 2 slowly lose heart, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, determine target pressure P1A and P2A of tested artery of upper extremity and tested artery of lower extremity respectively, determine the method following 5-1 respectively of this target pressure P1A and P2A) and 5-2):
5-1) for the air pressure and the pulse signal that are detected the first cuff 1 by the first pressure transducer, waveform is as shown in the P1 (t) of Fig. 5 He A1 (t), when the pulse signal A1 (t1) in tri-continuous moment of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) <A1 (t2) >A1 (t3) relation, then the air pressure that the t2 moment is corresponding is target pressure P1A;
5-2) for the air pressure and the pulse signal that are detected the second cuff 2 by the second pressure transducer, waveform is as shown in the P2 (t) of Fig. 5 He A2 (t), when the pulse signal A2 (t21) in tri-continuous moment of t21, t22 and t23 being detected, A2 (t22), when A21 (t23) meets A2 (t21) <A2 (t22) >A2 (t23) relation, then the air pressure that the t22 moment is corresponding is target pressure P2A;
6) continue slowly to lose heart to the first cuff 1 and the second cuff 2, in the process that the first cuff 1 and the second cuff 2 slowly lose heart, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine the diastolic pressure of tested artery of upper extremity and tested artery of lower extremity respectively;
7) be increased to respectively within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg by the air pressure of the first cuff 1 and the second cuff 2, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first and second gas bleeder valves, open the first and second air pumps, respectively the first cuff 1 and the second cuff 2 are pressurizeed, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close the first and second air pumps, stop pressurization;
7-2) open the first and second gas bleeder valves, exit to respectively the first cuff 1 and the second cuff 2, until discharge, then wait for a period of time, close the first and second gas bleeder valves again, open the first and second air pumps, respectively the first cuff 1 and the second cuff 2 are pressurizeed, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close the first and second air pumps, stop pressurization;
8) pulse signal of in the first cuff 1 and the second cuff 2 more than three is detected respectively by the first pressure transducer and the second pressure transducer, according to the pulse signal of described first cuff 1 and the second cuff 2, determine the pulse signal transmission time difference of measured.Determine that the method for the pulse signal transmission time difference of measured has two kinds, respectively following 8-1) and 8-2):
The pulse signal of a given number in eight to ten six 8-1) is detected in the first cuff 1 and the second cuff 2 respectively by the first pressure transducer and the second pressure transducer, calculate the described given number in the pulse signal of the described given number in the second cuff 2 and the first cuff 1 pulse signal between time difference, such as given number is 12, its waveform is as shown in C2A and C1A in Fig. 6, first calculate d1=t26-t6, d2=t27-t7, d3=t28-t8, d4=t29-t9, d5=t30-t10, d6=t31-t11, d7=t32-t12, d8=t33-t13, d9=t34-t14, d10=t35-t15, d11=t36-t16, d12=t37-t17, calculate the meansigma methods of d1 ~ d12 again, described meansigma methods is exactly the pulse signal transmission time difference of measured,
The pulse signal of in the first cuff 1 and the second cuff 2 more than three 8-2) is detected respectively by the first pressure transducer and the second pressure transducer, the time calculating correlation function maximum between pulse signal described in pulse signal described in the second cuff 2 and the first cuff 1 determines the time difference between described pulse signal, such as given number is 12, its waveform is as shown in C2A and C1A in Fig. 6, account form has two kinds, respectively following 8-2-1) and 8-2-2):
8-2-1) establish wave function y (t) of 12 pulse signal C2A of the second cuff 2,0≤t≤T, the wave function of 12 pulse signal C1A of the first cuff 1 is x (t), 0≤t≤T, calculate the correlation function R (τ) of y (t) and x (t), computing formula is calculate τ-value corresponding when described correlation function R (τ) gets maximum again, if described τ-value is τ 0, then τ 0 is exactly the pulse signal transmission time difference of measured;
The pulse signal wave function of 12 pulse signal C2A of the second cuff 2 8-2-2) is established to be respectively q1 (t), q2 (t), q3 (t), q4 (t), q5 (t), q6 (t), q7 (t), q8 (t), q9 (t), q10 (t), q11 (t), q12 (t), and 0≤t≤T, the pulse signal wave function of 12 pulse signal C1A of the first cuff 1 is p1 (t), p2 (t), p3 (t), p4 (t), p5 (t), p6 (t), p7 (t), p8 (t), p9 (t), p10 (t), p11 (t), p12 (t), and 0≤t≤T, calculate the correlation function Ri (τ) of qi (t) and pi (t) respectively, wherein 0≤i≤T and be integer, computing formula is calculate τ-value corresponding when 12 correlation function R1 (τ) get maximum to R12 (τ) more respectively, if described τ-value is respectively τ 1, τ 2, τ 3, τ 4, τ 5, τ 6, τ 7, τ 8, τ 9, τ 10, τ 11 and τ 12, calculate the meansigma methods of τ 1 to τ 12 again, described meansigma methods is exactly the pulse signal transmission time difference of measured,
9) open the first and second gas bleeder valves, lose heart to the first cuff 1 and the second cuff 2.
10) calculate an index of measured Degree of arteriosclerosis, described index is the second cuff lashing location to the distance of heart and the first cuff lashing location to the difference of the distance of heart divided by the value of calculation that the pulse signal transmission time difference of described measured obtains.
The second step, for Fig. 7, has following steps:
1) the first cuff 1 and the second cuff 2 are bundled on a tested upper limb and tested lower limb respectively, and are connected with the upper limb balloon interface on main frame 3 and lower limb balloon interface respectively with the second trachea 5 by the first trachea 4;
2) press the start key of main frame 3 keyboard, the first and second gas bleeder valves cut out, and the first and second air pumps are inflated respectively to the first cuff 1 and the second cuff 2, and the air pressure of the first cuff 1 and the second cuff 2 slowly increases from zero;
3) in the process that the first cuff 1 and the second cuff 2 are slowly pressurizeed, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine the diastolic pressure of tested artery of upper extremity and tested artery of lower extremity respectively;
4) continue slowly to pressurize to the first cuff 1 and the second cuff 2, in the process that the first cuff 1 and the second cuff 2 slowly pressurize, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, determine target pressure P1A and P2A of tested artery of upper extremity and tested artery of lower extremity respectively, determine the method following 4-1 respectively of this target pressure P1A and P2A) and 4-2):
4-1) for the air pressure and the pulse signal that are detected the first cuff 1 by the first pressure transducer, waveform is as shown in the P1 (t) of Fig. 6 He A1 (t), when the pulse signal A1 (t41) in tri-continuous moment of t41, t42 and t43 being detected, A1 (t42), when A1 (t43) meets A1 (t41) <A1 (t42) >A1 (t43) relation, then the air pressure that the t42 moment is corresponding is target pressure P1A;
4-2) for the air pressure and the pulse signal that are detected the second cuff 2 by the second pressure transducer, waveform is as shown in the P2 (t) of Fig. 6 He A2 (t), when the pulse signal A2 (t61) in tri-continuous moment of t61, t62 and t63 being detected, A2 (t62), A2 (t63) meets A2 (t61) <A2 (t62) >A2 (t63), then the air pressure that the t62 moment is corresponding is target pressure P2A;
5) continue slowly to pressurize to the first cuff 1 and the second cuff 2, in the process that the first cuff 1 and the second cuff 2 slowly pressurize, air pressure and the pulse signal of constantly change in the first cuff 1 and the second cuff 2 is detected respectively by the first pressure transducer and the second pressure transducer, according to described pulse signal and atmospheric pressure value, utilize oscillographic method principle, determine the systolic pressure of tested artery of upper extremity and tested artery of lower extremity respectively;
6) air pressure of the first cuff 1 and the second cuff 2 is reduced respectively or is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg, this step has two kinds of embodiments, respectively following 6-1) and 6-2):
6-1) open the first gas bleeder valve and the second gas bleeder valve, respectively the first cuff 1 and the second cuff 2 are lost heart, the air pressure of the first cuff 1 and the second cuff 2 is reduced within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is reduced to target pressure P1A and P2A respectively, close the first gas bleeder valve and the second gas bleeder valve, stop losing heart;
6-2) open the first gas bleeder valve and the second gas bleeder valve, exit to respectively the first cuff 1 and the second cuff 2, until discharge, then wait for a period of time, close the first gas bleeder valve and the second gas bleeder valve again, open the first air pump and the second air pump, respectively the first cuff 1 and the second cuff 2 are pressurizeed, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close the first air pump and the second air pump, stop pressurization,
7) pulse signal of in the first cuff 1 and the second cuff 2 more than three is detected respectively by the first pressure transducer and the second pressure transducer, according to the pulse signal of described first cuff 1 and the second cuff 2, determine the pulse signal transmission time difference of measured.Determine that the method for the pulse signal transmission time difference of measured has two kinds, respectively following 7-1) and 7-2):
The pulse signal of a given number in eight to ten six 7-1) is detected in the first cuff 1 and the second cuff 2 respectively by the first pressure transducer and the second pressure transducer, calculate the described given number in the pulse signal of the described given number in the second cuff 2 and the first cuff 1 pulse signal between time difference, such as given number is 12, its waveform is as shown in C2A and C1A in Fig. 8, first calculate d21=t66-t46, d22=t67-t47, d23=t68-t48, d24=t69-t49, d25=t70-t50, d26=t71-t51, d27=t72-t52, d28=t73-t53, d29=t74-t54, d30=t75-t55, d31=t76-t56, d32=t77-t57, calculate the meansigma methods of d21 ~ d32 again, described meansigma methods is exactly the pulse signal transmission time difference of measured,
The pulse signal of in the first cuff 1 and the second cuff 2 more than three 7-2) is detected respectively by the first pressure transducer and the second pressure transducer, the time calculating correlation function maximum between pulse signal described in pulse signal described in the second cuff 2 and the first cuff 1 determines the time difference between described pulse signal, such as given number is 12, its waveform is as shown in C2A and C1A in Fig. 8, account form has two kinds, respectively following 7-2-1) and 7-2-2):
7-2-1) establish wave function y (t) of 12 pulse signal C2A of the second cuff 2,0≤t≤T, the wave function of 12 pulse signal C1A of the first cuff 1 is x (t), 0≤t≤T, calculate the correlation function R (τ) of y (t) and x (t), computing formula is calculate τ-value corresponding when described correlation function R (τ) gets maximum again, if described τ-value is τ 0, then τ 0 is exactly the pulse signal transmission time difference of measured;
The pulse signal wave function of 12 pulse signal C2A of the second cuff 2 7-2-2) is established to be respectively q1 (t), q2 (t), q3 (t), q4 (t), q5 (t), q6 (t), q7 (t), q8 (t), q9 (t), q10 (t), q11 (t), q12 (t), and 0≤t≤T, the pulse signal wave function of 12 pulse signal C1A of the first cuff 1 is p1 (t), p2 (t), p3 (t), p4 (t), p5 (t), p6 (t), p7 (t), p8 (t), p9 (t), p10 (t), p11 (t), p12 (t), and 0≤t≤T, calculate the correlation function Ri (τ) of qi (t) and pi (t) respectively, wherein 0≤i≤12 and be integer, computing formula is calculate τ-value corresponding when 12 correlation function R1 (τ) get maximum to R12 (τ) more respectively, if described τ-value is respectively τ 1, τ 2, τ 3, τ 4, τ 5, τ 6, τ 7, τ 8, τ 9, τ 10, τ 11 and τ 12, calculate the meansigma methods of τ 1 to τ 12 again, described meansigma methods is exactly the pulse signal transmission time of measured,
8) open gas bleeder valve 1 and gas bleeder valve 2, lose heart to the first cuff 1 and the second cuff 2.
9) calculate an index of measured Degree of arteriosclerosis, described index is the second cuff lashing location to the distance of heart and the first cuff lashing location to the difference of the distance of heart divided by the value of calculation that the pulse signal transmission time difference of described measured obtains.
Embodiment two
As shown in Figure 2, following a kind of step is had:
For Fig. 5, only need to use the first step of Fig. 1, and by the step 2 in described step), 3) and 7) use following steps 2 respectively), 3) and 7) replace:
2) start key of main frame 3 keyboard is pressed, first gas bleeder valve and the second gas bleeder valve are closed, timesharing opens the first switch valve, close second switch valve, open air pump inflates and opens second switch valve to the first cuff 1, closes the first switch valve, opens air pump and inflate to the second cuff 2, and the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close air pump, stop inflation;
7) be increased to respectively within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg by the air pressure of the first cuff 1 and the second cuff 2, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first gas bleeder valve and the second gas bleeder valve, timesharing opens the first switch valve, close second switch valve, open air pump inflates and opens second switch valve to the first cuff 1, closes the first switch valve, opens air pump and inflate to the second cuff 2, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close air pump, stop pressurization;
7-2) open the first gas bleeder valve and the second gas bleeder valve, exit to respectively the first cuff 1 and the second cuff 2, until discharge, then wait for a period of time, close the first gas bleeder valve and the second gas bleeder valve again, the first switch valve is opened in timesharing, close second switch valve, open air pump and inflate and open second switch valve to the first cuff 1, close the first switch valve, open air pump to inflate to the second cuff 2, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close air pump, stop pressurization.
Embodiment three
As shown in Figure 3, following a kind of step is had:
For Fig. 5, only need to use the first step of Fig. 1, and by the step 2 in described step), 3) and 7) use following steps 2 respectively), 3) and 7) replace:
2) start key of main frame 3 keyboard is pressed, first gas bleeder valve and the second gas bleeder valve are closed, three-way air valve connected air pump and the first cuff 1 by timesharing, open air pump inflates and is connected by three-way air valve air pump and the second cuff 2, opens air pump and inflate to the second cuff 2 to the first cuff 1, the air pressure of the first cuff 1 and the second cuff 2 increases from zero;
3) when the air pressure in the first cuff 1 and the second cuff 2 is greater than systolic pressure respectively, close air pump, stop inflation;
7) be increased to respectively within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg by the air pressure of the first cuff 1 and the second cuff 2, this step has two kinds of embodiments, respectively following 7-1) and 7-2):
7-1) close the first gas bleeder valve and the second gas bleeder valve, three-way air valve connected air pump and the first cuff 1 by timesharing, open air pump inflates and is connected by three-way air valve air pump and the second cuff 2, opens air pump and inflate to the second cuff 2 to the first cuff 1, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close air pump, stop pressurization;
7-2) open the first gas bleeder valve and the second gas bleeder valve, exit to respectively the first cuff 1 and the second cuff 2, until discharge, then wait for a period of time, close the first gas bleeder valve and the second gas bleeder valve again, three-way air valve is connected air pump and the first cuff 1 by timesharing, open air pump and inflate and connected by three-way air valve air pump and the second cuff 2 to the first cuff 1, open air pump to inflate to the second cuff 2, the air pressure of the first cuff 1 and the second cuff 2 is increased within the scope of target pressure P1A or P1A ± 10mmHg and within the scope of P2A or P2A ± 10mmHg respectively, such as the air pressure of the first cuff 1 and the second cuff 2 is increased to target pressure P1A and P2A respectively, close air pump, stop pressurization.
Above content converts bright further in detail in conjunction with concrete preferred implementation is made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention; make some equivalent alternative or obvious modification without departing from the inventive concept of the premise; and performance or purposes identical, all should be considered as belonging to patent protection model that the present invention determines by submitted to claims with.

Claims (7)

1. an arteriosclerosis measuring device, is characterized in that, comprising:
For first cuff of colligation at upper limb position;
For second cuff of colligation at lower extremity;
The first pressure transducer be connected with described first cuff;
The second pressure transducer be connected with described second cuff;
For the more than one air pump inflated described first cuff and/or the second cuff;
To the first gas bleeder valve that described first cuff loses heart;
To the second gas bleeder valve that described second cuff loses heart;
Microprocessor, for controlling described air pump, gas bleeder valve, for the treatment of the pressure signal in the first cuff obtained respectively by the first pressure transducer, the second pressure transducer, the second cuff and/or pulse signal, described microprocessor performs the arteriosclerosis measuring process comprised the following steps:
A, use the first cuff, air pump, the first pressure transducer and the first gas bleeder valve, measure described artery of upper extremity blood pressure, and pulse signal amplitude in the first cuff of sening as an envoy to of simultaneously measuring reaches maximum cuff pressure P1A; Use the second cuff, air pump, the second pressure transducer and the second gas bleeder valve, measure described artery of lower extremity blood pressure, and measurement makes pulse signal amplitude in the second cuff reach maximum cuff pressure P2A simultaneously;
B, the force value by described air pump described first cuff is pressurized within the scope of P1A ± 10mmHg, by described air pump the second cuff is pressurized to a force value within the scope of P2A ± 10mmHg, then measured the pulse signal of more than three in described first cuff and the second cuff by described first pressure transducer and the second pressure transducer simultaneously respectively;
C, calculate time difference between the pulse signal of more than three in described second cuff and the pulse signal of more than three in described first cuff, be specially: determine the time difference between described pulse signal by the time calculating correlation function maximum between the pulse signal of more than three in described second cuff and the pulse signal of more than three in described first cuff;
Measured's Degree of arteriosclerosis is determined with this.
2. arteriosclerosis measuring device as claimed in claim 1, it is characterized in that: calculate a given number in eight to ten six in the pulse signal of a given number in eight to ten six in described second cuff and described first cuff pulse signal between time difference, determine measured's Degree of arteriosclerosis with this.
3. arteriosclerosis measuring device as claimed in claim 1 or 2, it is characterized in that: described measured's Degree of arteriosclerosis is an index, the described index value of calculation that to be the second cuff lashing location obtain divided by the time difference between described pulse signal to the distance of heart and the first cuff lashing location to the difference of the distance of heart.
4. arteriosclerosis measuring device as claimed in claim 1, it is characterized in that, the method calculating the time difference between described pulse signal is:
If wave function y (t) of n pulse signal C2A of described second cuff, 0≤t≤T, the wave function of n pulse signal C1A of described first cuff is x (t), 0≤t≤T, calculate the correlation function R (τ) of described y (t) and x (t), computing formula is, calculate τ-value corresponding when described correlation function R (τ) gets maximum again, if described τ-value is τ 0, then τ 0 is exactly the pulse signal transmission time difference of measured.
5. arteriosclerosis measuring device as claimed in claim 1, it is characterized in that, the method calculating the time difference between described pulse signal is:
If the pulse signal wave function of n pulse signal C2A of described second cuff is respectively q1 (t), q2 (t) ... qn (t), and 0≤t≤T, the pulse signal wave function of n pulse signal C1A of described first cuff is p1 (t), p2 (t) ... pn (t), and 0≤t≤T, calculate the correlation function Ri (τ) of described qi (t) and pi (t) respectively, wherein 0≤i≤n and be integer, computing formula is, calculate τ-value corresponding when described n correlation function R1 (τ) gets maximum to Rn (τ) more respectively, if described τ-value is respectively τ 1, τ 2... τ n, calculate the meansigma methods of described τ 1 to τ n again, described meansigma methods is exactly the pulse signal transmission time difference of measured.
6. arteriosclerosis measuring device as claimed in claim 1 or 2, it is characterized in that: use pressurization measurement method or decompression measurement method, for air pressure P1 (t) and pulse signal A1 (t) that are detected described first cuff by described first pressure transducer, when the pulse signal A1 (t1) in tri-continuous moment of t1, t2 and t3 being detected, A1 (t2), when A1 (t3) meets A1 (t1) <A1 (t2) >A1 (t3) relation, then the air pressure that the t2 moment is corresponding is target pressure P1A.
7. arteriosclerosis measuring device as claimed in claim 1 or 2, it is characterized in that: use pressurization measurement method or decompression measurement method, for air pressure P2 (t) and pulse signal A2 (t) that are detected described second cuff by described second pressure transducer, when the pulse signal A2 (t21) in tri-continuous moment of t21, t22 and t23 being detected, A2 (t22), when A2 (t23) meets A2 (t21) <A2 (t22) >A2 (t23) relation, then the air pressure that the t22 moment is corresponding is target pressure P2A.
CN201310543836.1A 2013-11-06 2013-11-06 Arteriosclerosis measuring device Expired - Fee Related CN103705224B (en)

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Publication number Priority date Publication date Assignee Title
US10058255B2 (en) 2014-05-29 2018-08-28 Hong Kong Applied Science And Technology Research Institute Co. Ltd. Method of determining stiffness index of an arterial network and system thereof
CN104958064A (en) * 2015-07-15 2015-10-07 四川宇峰科技发展有限公司 Wearable arteriosclerosis detector and pulse wave velocity detecting method
CN106371564B (en) * 2015-08-28 2020-06-23 北京智谷睿拓技术服务有限公司 Input information determination method and device
CN106073732A (en) * 2016-07-29 2016-11-09 刘琼 Cardiovascular arteriosclerosis detecting device
CN107411724A (en) * 2017-07-27 2017-12-01 悦享趋势科技(北京)有限责任公司 Artery sclerosis measuring instrument and artery sclerosis measuring method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4245648A (en) * 1978-09-20 1981-01-20 Trimmer Gordon A Method and apparatus for measuring blood pressure and pulse rate
CN1325285A (en) * 1998-08-24 2001-12-05 马丁·C·巴鲁克 Apparatus and method for measuring pulse transit time
EP1203558A2 (en) * 2000-11-06 2002-05-08 Colin Corporation Superior-and-inferior-limb blood-pressure index measuring apparatus
KR20090127517A (en) * 2008-06-09 2009-12-14 (주)아이베이지디쓰리 Heart monitoring system
CN102223837A (en) * 2008-11-20 2011-10-19 欧姆龙健康医疗事业株式会社 Blood pressure information measuring device for measuring pulse wave velocity as blood pressure information

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001321347A (en) * 2000-05-16 2001-11-20 Nippon Koden Corp Blood pressure monitoring device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4245648A (en) * 1978-09-20 1981-01-20 Trimmer Gordon A Method and apparatus for measuring blood pressure and pulse rate
CN1325285A (en) * 1998-08-24 2001-12-05 马丁·C·巴鲁克 Apparatus and method for measuring pulse transit time
EP1203558A2 (en) * 2000-11-06 2002-05-08 Colin Corporation Superior-and-inferior-limb blood-pressure index measuring apparatus
KR20090127517A (en) * 2008-06-09 2009-12-14 (주)아이베이지디쓰리 Heart monitoring system
CN102223837A (en) * 2008-11-20 2011-10-19 欧姆龙健康医疗事业株式会社 Blood pressure information measuring device for measuring pulse wave velocity as blood pressure information

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