CN103860160B - A kind of wireless and passive gastrointestinal stress detection system - Google Patents
A kind of wireless and passive gastrointestinal stress detection system Download PDFInfo
- Publication number
- CN103860160B CN103860160B CN201210535825.4A CN201210535825A CN103860160B CN 103860160 B CN103860160 B CN 103860160B CN 201210535825 A CN201210535825 A CN 201210535825A CN 103860160 B CN103860160 B CN 103860160B
- Authority
- CN
- China
- Prior art keywords
- capsule
- gastrointestinal
- frequency
- internal
- impedance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses the gastrointestinal stress of a kind of wireless and passive detection system, belong to medical instruments field. This system includes internal and external two parts, outer body is made up of the read coil soft ribbons being enclosed within outside trunk and portable electric impedance analyzer, internal body portion is one form the pressure transducer capsule of LC oscillation circuit by inductance and presser sensor electric capacity, and internal and outer body wirelessly realizes information transmission and detects. Sensor capsule simple in construction in this system body, volume is little, cost is low, bowel relieving, fasting is not needed before inspection, testing result can reflect the gastrointestinal pressure under physiological status and kinestate completely, additionally this capsule can carry out the detection of long-term gastrointestinal stress without energy supply, provides in real time for clinical diagnosis and treatment, data accurately.
Description
Technical field
The present invention relates to medical instruments field, particularly relate to a kind of gastrointestinal based on LC oscillation circuit and Mutual Inductance Coupling principle and press detection system.
Background technology
Functional gastrointestinal disorder disease worldwide sickness rate is higher and has day by day ascendant trend. In every-day medical works, there are about nearly 50% patient and go to a doctor because of the gastrointestinal symptom such as abdominal distention, stomachache, wherein 30~40% be finally diagnosed as gastrointestinal tract dyskinesis disease. Especially in recent years, the living standard of our people improves constantly, and dietary structure is continually changing, operating pressure abruptly increase, and gastrointestinal tract dyskinesis disease also gets more and more, and becomes one of modal digestive system disease.
Gastrointestinal tract pressure measurement it will be seen that the Pressure Variation in gastrointestinal tract, and the diagnosis of digestive tract power is had important reference value. The method of record cavity pressure medically conventional at present mainly has two kinds, a kind of for pressure transducer capillary tube hydraulic pressure perfusion in vitro, another kind is intracavity micro pressure sensor tremie method, but both approaches is invasive detection methods, need to insert the catheter into gastrointestinal tract, patient suffering is big, and compliance is poor. Patient needs bowel relieving, fasting before checking, therefore testing result can not reflect the colonic pressure under physiological status and kinestate completely, and the insertion of conduit makes detected person be in improper physiological status, it is impossible to obtains true and reliable data. In addition, from the fifties in last century, physiological parameter radio pill receives to be paid attention to widely, have become as one of current focus studied in the world, the main point both direction of its design, one is utilize battery for signal emission module energy supply, by the pressure signal modulate emission that senses to receiver module; Another is utilize power conversion circuits to collect storage electromagnetic wave energy and is transmitter module energy supply. Fig. 1 a and Fig. 1 b respectively illustrates and utilizes battery for signal emission module energy supply in prior art, by telemetry system illustraton of model to receiver module of the pressure signal modulate emission that senses and Pressure capsule module map, can be seen that this system needs special modulate emission and receives unit, and be the power module (battery or power conversion circuits) making its job demand special.
And above-mentioned physiological parameter radio pill, the first utilizes battery for signal emission module energy supply, by the pressure signal modulate emission that senses to receiver module, it major downside is that application life depends on battery life, and battery can occupy major part volume and there is leakage problem. The second utilizes power conversion circuits to collect storage electromagnetic wave energy and for transmitter module energy supply, it main disadvantage is that Circuits System complexity cost is high, and supply energy efficiency low. Overwhelming majority gastrointestinal stress radio pill is still within laboratory stage at present, and only minority radio pill has put into clinical practice. Putting into the gastrointestinal pressure radio pill of clinical practice, still mainly be limited to energy consumption and energy supply problem, the cost height testing time is short, it is impossible to meet the needs of the gastrointestinal long-time diagnosis and treatment of all-digestive tract disease.
Summary of the invention
The present invention solves that the problems referred to above propose a kind of gastrointestinal based on LC oscillation circuit and Mutual Inductance Coupling principle and press detection system, it is possible to achieve gastrointestinal stress is monitored continuously for a long time.
Gastrointestinal based on LC oscillation circuit and Mutual Inductance Coupling principle disclosed by the invention presses detection system, comprising:
Internal LC tank pressure sensor capsule, is used for sensing gastrointestinal stress change;
External read coil soft ribbons, for producing Mutual Inductance Coupling signal with the LC oscillation circuit in described internal LC tank pressure sensor capsule;
Portable electric impedance analyzer, it is worn on external, for producing swept-frequency signal so that the impedance of the described external read coil soft ribbons after reading Mutual Inductance Coupling, and after this impedance is analyzed, obtain the frequency at impedance phase minima place, set up this frequency and the relation of presser sensor electric capacity pressure in LC oscillation circuit capsule, be used for reflecting gastrointestinal stress monitoring result
The above-mentioned gastrointestinal based on LC oscillation circuit and Mutual Inductance Coupling principle disclosed in this invention presses detection system to have the advantage that
A, program application LC oscillation circuit and Mutual Inductance Coupling principle, it is not necessary to special signal emission module, simplify system structure.
B, LC tank pressure sensor capsule structure is simple, only comprises presser sensor electric capacity and inductance, Non-energy-consumption, does not need the supply modules such as battery, and cost is low, it may be achieved long-time monitoring continuously.
C, the simple volume of pressure transducer capsule structure are little, without lead-out wire, it is achieved that patient's no pain, hurtless measure, it is not necessary to monitoring to gastrointestinal pressure and kinestate under the normal physiological condition of bowel relieving and fasting.
D, read coil soft ribbons utilize Helmholtz coil principle to achieve the inductively enhancing in coil distance situation farther out in vivo and in vitro.
The simple small and exquisite easy operation of e, portable electric impedance analyzer, it is simple to wear, utilizes frequency sweep control and data processing algorithm to achieve Frequency point and finely finds, shows in real time and pressure record.
Accompanying drawing explanation
Fig. 1 a and 1b is the structural representation of battery class physiological parameter telemetry system and capsule in prior art;
Fig. 2 is the structural representation detecting system in the present invention based on the gastrointestinal stress of LC oscillation circuit and Mutual Inductance Coupling principle;
Fig. 3 is the fundamental diagram in the present invention based on LC oscillation circuit and Mutual Inductance Coupling.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly understand, below in conjunction with specific embodiment, and with reference to accompanying drawing, the present invention is described in more detail.
The present invention is that a kind of gastrointestinal stress based on LC oscillation circuit and Mutual Inductance Coupling principle detects system, as in figure 2 it is shown, this system includes being positioned at internal LC oscillation circuit capsule, external read coil soft ribbons and portable electric impedance analyzer.Wherein, internal LC tank pressure sensor capsule is used for sensing gastrointestinal stress change; External read coil soft ribbons is for LC oscillation circuit signal in Mutual Inductance Coupling body; Portable electric impedance analyzer is worn on external, produce swept-frequency signal and be used for the external read coil soft ribbons impedance after reading Mutual Inductance Coupling, portable electric impedance analyzer receives, store this impedance treated analysis after obtain the frequency at impedance phase minima place, set up this frequency and the relation of presser sensor electric capacity pressure in LC oscillation circuit capsule, be used for reflecting gastrointestinal stress monitoring result; Internal pressure transducer capsule and vitro detection part realize being wirelessly transferred of information by Mutual Inductance Coupling.
The operation principle of native system is as it is shown on figure 3, based on LC oscillation circuit and Mutual Inductance Coupling principle, the internal inductive sensor L in LC tank sensor capsuleS, presser sensor electric capacity CSA natural resonance frequency f is produced time in parallelS, wherein capsule internal resistance is RS,
When Time,
Gastrointestinal stress changes the capacitance C causing pressure sensitization capacitance in described sensor capsuleSChange, and then cause the natural resonance frequency f of LC oscillation circuitSChange. External read coil soft ribbons LRInductive sensor L with LC tank sensor capsuleSMutual Inductance Coupling occurs, and the LC oscillation circuit natural resonance frequency change of sensor capsule causes the impedance Z of external read coil soft ribbonsiChange,
Wherein f is the swept frequency of the swept-frequency signal that described portable electric impedance analyzer produces, LRIt is the own inductance of external read coil soft ribbons,Being the quality factor of LC tank sensor capsule, k is the coefficient of coup of Mutual Inductance Coupling. By formula (2) known ZiPhase place at natural resonance frequency fSThere is a minima in place, analyzes Z by portable electric impedance analyzeriPhase minimum point obtain the natural resonance frequency of vivo sensing device capsule, this natural frequency is substituted into and counter in formula (1) pushes away the capacitance C that can draw presser sensor electric capacityS, the capacitance C of presser sensor electric capacity after comparison demarcationSWith the relation of impressed pressure P, thus drawing gastrointestinal stress size.
Further, above-mentioned LC tank pressure sensor capsule structure simply only comprises presser sensor electric capacity and inductance, does not need the supply modules such as battery, Non-energy-consumption, it may be achieved monitor for a long time. Wherein presser sensor constant volume is the silicon capacitive pressure transducer that MEMS processing technique is made, and inductance is the inductance coil of the MEMS inductance processed or traditional method coiling. The application of MEMS technology makes this capsule volume little, and diameter is less than or equal to 9mm, and length is less than or equal to 20mm, and its shell is biocompatible material, can directly take, with low cost, it is simple to make disposable Orally taken product. Not needing bowel relieving, fasting before taking this capsule, therefore testing result can reflect the colonic pressure under physiological status and kinestate completely simultaneously.
Described external read coil soft ribbons is only one group of tubbiness spiral winding, material is copper cash or other low resistance metal wires, this tubbiness spiral winding receives the swept-frequency signal of portable electric impedance analyzer output, and produces at the substantially homogeneous electromagnetic fiele of gastrointestinal part for Mutual Inductance Coupling.
Described portable electric impedance analyzer includes master controller, Direct Digital Frequency Synthesizers (DDS), high-speed AD converter (ADC), read coil drive circuit and liquid crystal display. Main controller controls DDS produces swept-frequency signal, and read coil drive circuit realizes the power amplification of swept-frequency signal, and gathers feedback signal. When the resonant frequency that swept-frequency signal output frequency is LC oscillation circuit, owing to Mutual Inductance Coupling causes that external read coil soft ribbons impedance changes, and then cause the feedback signal amplitude, the phase change that collect.This signal calculates the impedance of external read coil soft ribbons after change after ADC changes by discrete Fourier transform, master controller can obtain the impedance spectrum figure of external read coil soft ribbons after completing frequency sweep, the noise in impedance spectrum is filtered by finite impulse response (FIR), determine that the position of resonant frequency, final conversion Calculation are gastrointestinal stress. The program of master controller first carries out coarse scanning and determines substantially resonance peak point, carries out close scanning afterwards and realizes being accurately positioned and make portable electric impedance analyzer can complete stomach pressure every 1s to read.
The present invention is compared with prior art, it is achieved that patient's no pain, hurtless measure, it is not necessary under the normal physiological condition of bowel relieving and fasting, gastrointestinal pressure and the continuous for a long time of kinestate are monitored. Present invention achieves the inductively enhancing in coil distance situation farther out in vivo and in vitro simultaneously, utilize frequency sweep control and data processing algorithm to achieve Frequency point and finely find and show in real time.
Particular embodiments described above; the purpose of the present invention, technical scheme and beneficial effect have been further described; it is it should be understood that; the foregoing is only specific embodiments of the invention; it is not limited to the present invention; all within the spirit and principles in the present invention, any amendment of making, equivalent replacement, improvement etc., should be included within protection scope of the present invention.
Claims (4)
1. detect a system based on the gastrointestinal stress of LC oscillation circuit and Mutual Inductance Coupling, comprising:
Internal LC tank pressure sensor capsule, is used for sensing gastrointestinal stress change;
External read coil soft ribbons, for producing Mutual Inductance Coupling signal with the LC oscillation circuit in described internal LC tank pressure sensor capsule;
Portable electric impedance analyzer, it is worn on external, for producing swept-frequency signal so that the impedance of the described external read coil soft ribbons after reading Mutual Inductance Coupling, and after this impedance is analyzed, obtain the frequency at impedance phase minima place, set up this frequency and the relation of presser sensor electric capacity pressure in LC oscillation circuit capsule, be used for reflecting gastrointestinal stress monitoring result;
Described internal LC tank pressure sensor capsule is made up of presser sensor electric capacity and inductance;
The shell of described internal LC tank pressure sensor capsule is biocompatible material, and diameter is less than or equal to 9mm, and length is less than or equal to 20mm;
Described external read coil soft ribbons is one group of tubbiness spiral winding, and material is copper cash or other low resistance metal wires, its produce in vivo the substantially homogeneous electromagnetic fiele of gastrointestinal part for Mutual Inductance Coupling;
Described portable electric impedance analyzer includes master controller, Direct Digital Frequency Synthesizers (DDS), high-speed AD converter (ADC), read coil drive circuit and LCDs; Direct Digital Frequency Synthesizers described in described main controller controls produces swept-frequency signal, described read coil drive circuit realizes the power amplification of swept-frequency signal, and gathering the Mutual Inductance Coupling signal that described external read coil soft ribbons produces with the LC oscillation circuit in described internal LC tank pressure sensor capsule, this Mutual Inductance Coupling signal calculates the impedance of external read coil soft ribbons after described high-speed AD converter is changed by discrete Fourier transform;
Presser sensor electric capacity in described internal LC tank pressure sensor capsule is the silicon capacitive pressure transducer that MEMS processing technique is made, and inductance is the inductance coil of the MEMS inductance processed or traditional method coiling.
2. gastrointestinal stress according to claim 1 detection system, it is characterised in that gastrointestinal stress changes the capacitance C causing described internal LC tank pressure sensor glue intraluminal pressure sensitization capacitanceSChange, and then cause the natural resonance frequency f of LC oscillation circuitSChanging, wherein said natural resonance frequency is calculated as below:
WhenTime,
Wherein, LSFor the faradism inductance value in internal LC tank sensor capsule, RSFor the resistance value in internal LC tank pressure sensor capsule.
3. gastrointestinal stress according to claim 2 detection system, it is characterised in that described natural resonance frequency fSChange cause the impedance Z of external read coil soft ribbonsiChanging, wherein said impedance is expressed as follows:
Wherein, f is the swept frequency of the swept-frequency signal that described portable electric impedance analyzer produces, LRIt is the own inductance of external read coil soft ribbons,Being the quality factor of described internal LC tank pressure sensor capsule, k is Mutual Inductance Coupling coefficient.
4. gastrointestinal stress according to claim 3 detection system, it is characterised in that described portable electric impedance analyzer is by analyzing ZiPhase minimum point, obtain vivo sensing device capsule natural resonance frequency fS, and according to described natural resonance frequency fSCalculate the capacitance C of described presser sensor electric capacityS, and the capacitance C according to described presser sensor electric capacitySWith the relation of impressed pressure P, and then draw gastrointestinal stress size.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210535825.4A CN103860160B (en) | 2012-12-12 | 2012-12-12 | A kind of wireless and passive gastrointestinal stress detection system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210535825.4A CN103860160B (en) | 2012-12-12 | 2012-12-12 | A kind of wireless and passive gastrointestinal stress detection system |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103860160A CN103860160A (en) | 2014-06-18 |
CN103860160B true CN103860160B (en) | 2016-06-15 |
Family
ID=50899591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210535825.4A Active CN103860160B (en) | 2012-12-12 | 2012-12-12 | A kind of wireless and passive gastrointestinal stress detection system |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103860160B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104545795B (en) * | 2015-02-09 | 2016-09-21 | 中国科学院电子学研究所 | Planar inductor and the wireless connections intraocular pressure sensor of capacitances in series |
TWI712432B (en) * | 2018-03-05 | 2020-12-11 | 鄭惇方 | Bio-energy signal capture and conversion device |
CN113405698A (en) * | 2021-05-11 | 2021-09-17 | 北京航空航天大学 | Stress measuring device and method |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6287253B1 (en) * | 1999-06-25 | 2001-09-11 | Sabolich Research & Development | Pressure ulcer condition sensing and monitoring |
CN102003973A (en) * | 2010-10-19 | 2011-04-06 | 首都医科大学 | Wireless passive measuring method and circuit |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8926524B2 (en) * | 2008-06-02 | 2015-01-06 | California Institute Of Technology | System, apparatus and method for biomedical wireless pressure sensing |
-
2012
- 2012-12-12 CN CN201210535825.4A patent/CN103860160B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6287253B1 (en) * | 1999-06-25 | 2001-09-11 | Sabolich Research & Development | Pressure ulcer condition sensing and monitoring |
CN102003973A (en) * | 2010-10-19 | 2011-04-06 | 首都医科大学 | Wireless passive measuring method and circuit |
Also Published As
Publication number | Publication date |
---|---|
CN103860160A (en) | 2014-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2012214727B2 (en) | System for detection of blood pressure using a pressure sensing guide wire | |
US20130225968A1 (en) | Integrated flexible passive sensor in a soft contact lens for iop monitoring | |
CN103860160B (en) | A kind of wireless and passive gastrointestinal stress detection system | |
JP2016518870A (en) | System including a guide wire for detecting fluid pressure | |
CN101856222A (en) | Implanted wireless electronic detection device | |
CN204428024U (en) | Implanted intracranial pressure wireless monitoring device | |
CN213430080U (en) | Implantable self-driven pressure sensor and pulmonary artery pressure wireless monitoring device | |
Cao et al. | A wireless strain sensor system for bladder volume monitoring | |
Aldaoud et al. | Design of a miniaturized wireless blood pressure sensing interface using capacitive coupling | |
CN101744620A (en) | Implantable wireless intracranial pressure automatic monitoring system | |
CN101849822B (en) | Implantable wireless intracranial pressure automatic monitoring method | |
CN102485167A (en) | Ultramicro implantation type blood pressure measuring and monitoring method and device | |
Ativanichayaphong et al. | An implantable batteryless wireless impedance sensor for gastroesophageal reflux diagnosis | |
CN105832327B (en) | A kind of passive monitoring intracranial pressure system of implantation type wireless | |
Shi et al. | In Vitro and In Vivo characterization of wireless and passive micro system enabling gastrointestinal pressure monitoring | |
CN201333032Y (en) | Implanted wireless automatic intracranial pressure monitoring system | |
Zhai et al. | Design and modelling of a passive wireless pressure sensor | |
CN108095715A (en) | A kind of passive intracranial pressure monitoring system of implantation type wireless | |
Moradi et al. | Analysis of biotelemetric interrogation of chronically implantable intracranial capacitive pressure sensor | |
CN102727199B (en) | Brain edema change measuring method based on minimum impedance frequency | |
TWI544902B (en) | Wireless detection system of physiological signals and method thereof | |
CN103829933A (en) | Method for detecting vessel stenosis based on double interventional pressure sensors | |
CN106983497A (en) | Monitoring system | |
Ativanichayaphong et al. | Development of an implanted RFID impedance sensor for detecting gastroesophageal reflux | |
CN109044382A (en) | A kind of bladder urine capacity monitoring system and its monitoring method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant |