CN103877662A - Hepatic artery medicine box retention catheter system - Google Patents
Hepatic artery medicine box retention catheter system Download PDFInfo
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- CN103877662A CN103877662A CN201410152089.3A CN201410152089A CN103877662A CN 103877662 A CN103877662 A CN 103877662A CN 201410152089 A CN201410152089 A CN 201410152089A CN 103877662 A CN103877662 A CN 103877662A
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- conduit
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- hepatic artery
- medicine box
- side opening
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Abstract
The invention relates to a hepatic artery medicine box retention catheter system which mainly comprises an in vivo retention catheter, a 2.6 to 3 F coaxial micro catheter and a micro guiding wire. The in vivo retention catheter comprises a far segment 2.6 to 3 F catheter, a near segment 4F catheter and a 2.6 to 3 F catheter and 4 F catheter connection part. An oval side hole is formed in the 4 F catheter and the short diameter of the side hole is slightly longer than the outer diameter of a cavity of the 2.6 to 3 F catheter. The length of the far segment 2.6 to 3 F catheter is 8 to 12 cm. By the adoption of the hepatic artery medicine box retention conduit system, the far segment of the retention catheter can enter the branch stomach omentum right artery of the gastroduodenal artery more easily, the far segment catheter is conveniently fixed, and filled medicine totally flows out of the side hole and an end hole does not need to be sealed. The filled medicine can enter and exit the micro catheter and the outer side of the retention catheter is fixed. The success rate of a hepatic artery medicine box retention catheter can be obviously improved, risks of catheter displacement and hepatic artery blocking are obviously reduced and the hepatic artery medicine box retention conduit system can be clinically and widely popularized and applied.
Description
Technical field
The present invention relates to a kind of Hepatic artery medicine box inlying catheter system, relate in particular to hepatic arterial infusion chemotherapy port catheter indwelling system, particularly a kind of novel one-sided approach, far-end fix, the tremulous pulse medicine box inlying catheter system of side opening perfusion, blockage resisting, anti-displacement.
Background technology
Hepatic artery chemotherapy is the treatment technology of approving in the world, and arterial chemotherapy especially Hepatic artery chemotherapy is obviously better than system intravenous chemotherapy effect, aspect treatment colorectal cancer hepatic metastases and other liver malignancies, is being widely used.About the foundation of Hepatic artery chemotherapy route of administration, be mainly divided into two kinds, one is that surgery is opened and under abdomen, implanted Hepatic artery medicine box, one is to get involved percutaneous puncture approach to implant Hepatic artery medicine box.Surgery is opened implantation under abdomen and, because wound is large, is seldom used.Get involved percutaneous puncture approach implantation due to Wicresoft, the feature such as quick, applies more clinically.But, the percutaneous using is at present got involved approach Hepatic artery Medication box implanting method, inlying catheter far-end stomidium is positioned at target vessel (proper hepatic artery), chemotherapeutic is through the stomidium perfusion of inlying catheter, there is following shortcoming in stomidium perfusion: (1) inlying catheter section far away is free in Hepatic artery, and conductor housing is often shifted.Especially in the very short situation of patient's proper hepatic artery, slight catheter displacement causes perfusion chemotherapy failure.(2) conductor housing and Hepatic artery wall often bump, and stimulate damage Hepatic artery, and the incidence rate of hepatic artery occlusion is higher.(3) in the time that serious blood vessel makes a variation or be tortuous, what stomidium poured into stays pipe mode technique successful rate extremely low.Above shortcoming has also restricted and has got involved being widely used of percutaneous approach tremulous pulse medicine box indwelling technology.
Summary of the invention
In order to overcome above-mentioned defect, the invention provides a kind of Hepatic artery medicine box inlying catheter system, mainly comprise intracorporeal indwelling conduit, the coaxial microtubular of 2.6～3F and micro-wire, it is characterized in that, described intracorporeal indwelling conduit comprises: section far away 2.6～3F conduit, nearly section 4F conduit, and 2.6～3F and 4F conduit connecting portion, this connecting portion size transition gradually, seriality and the compliance of guarantee conduit; Far-end at 4F conduit is provided with metal marker, on 4F conduit with the spaced apart side opening that is provided with of nearside of this metal marker, the minor axis of described oval side opening is slightly larger than the overall diameter of 2.6～3F conduit, and section far away 2.6～3F catheter length is 8～12cm, and its stomidium or inner chamber are without shutoff.
Further, described 2.6～3F catheter length is 10cm; Section far away 2.6～3F catheter design is convenient to enter smooth right gastroepiploic artery, and does not need closed inner chamber.
Further, described side opening, for being oval, is opened in 4F conduit section far away portion, and the minor axis of oval side opening is slightly larger than 2.6～3F conduit overall diameter, is convenient to medicine and flows out from side opening, is also convenient to 2.6～3F microtubular and comes in and goes out and operate through this side opening.
Further, the length of described 2.6～3F and 4F conduit connecting portion is made as 1cm.
Preferably, described metal marker adopts platinum to be embedded in tube wall, is positioned at far-end nearside 0.5～2cm place of 4F conduit, for accurately locating the position of near-end side opening.
Especially, platinum labelling is positioned at the far-end nearside 1cm place of 4F conduit.
Further, described side opening is opened the nearside 2～4mm place at 4F distal end of catheter metal marker.
Preferably, described side opening is opened the nearside 3mm place at 4F distal end of catheter metal marker.
Further, the length of described 4F conduit is 60～80cm, is preferably 70cm; The coaxial microtubular of described 2.6～3F, length is 115～145cm; Described micro-wire, diameter 0.36～0.46mm, length 180～220cm.
Preferably, the length of the coaxial microtubular of described 2.6～3F is 130cm; The length of micro-wire is 200cm.
Tremulous pulse medicine box inlying catheter system of the present invention, be used for getting involved percutaneous puncture approach chemotherapy medicine box is retained in to Hepatic artery, select the design of 2.6～3F microtubular for far away section of inlying catheter, make it more easily enter branch's right gastroepiploic artery of gastroduodenal artery, side opening is opened in far away section of 4F conduit place, when low discharge arterial perfusion, chemotherapeutic flows out through side opening completely, do not need thromboembolism sealing section far away 2.6～3F tube chamber, and by 4F conduit side opening turnover 2.6～3F microtubular, far away section of 2.6～3F conduit effectively fixed, prevented catheter displacement.This invention obviously improves the success rate of Hepatic artery medicine box inlying catheter, significantly reduces the arterial occlusive risk of catheter displacement regulating liver-QI, can clinical wide popularization and application.
Brief description of the drawings
Fig. 1 is the side hole type tremulous pulse medicine box inlying catheter system of invention;
Fig. 1 (A) is inlying catheter;
Fig. 1 (B) is coaxial microtubular;
Fig. 1 (C) is micro-wire;
Fig. 2 is side hole type Hepatic artery medicine box inlying catheter Operation ideograph of the present invention.
Wherein, 1, section far away 2.6～3F conduit; 2, connecting portion; 3, nearly section 4F conduit; 4, metal marker; 5, side opening; 6, proper hepatic artery; 7, right gastric artery; 8, left gastric artery; 9, splenic artery; 10, gastroduodenal artery; 11, right gastroepiploic artery; 12, liver left and right tremulous pulse and branch thereof; 13, turn sealing.
Detailed description of the invention
Following examples are only for technical scheme of the present invention is more clearly described, and can not limit the scope of the invention with this.Censure specific features as used some vocabulary in the middle of description and claim.Those skilled in the art should understand, and goods producer may call same parts with different nouns.This specification and claims are not used as distinguishing the mode of parts with the difference of title, but the difference in function is used as the criterion of distinguishing with parts.Description subsequent descriptions is for implementing preferred embodiments of the present invention, and right described description is to illustrate that this novel rule is object, not in order to limit scope of the present invention.Protection scope of the present invention is when being as the criterion depending on the claims person of defining.
Below in conjunction with the drawings and specific embodiments, the present invention is described in further details.
In order to overcome defect of the prior art, the invention provides a kind of tremulous pulse medicine box indwelling system
Shown in Fig. 1, the present invention relates to a kind of Novel liver tremulous pulse medicine box indwelling system, mainly comprise: intracorporeal indwelling conduit (Figure 1A), the coaxial microtubular of 2.6～3F (Figure 1B), 0.014～0.018 inch of (0.36～0.46mm) micro-wire (Fig. 1 C).
Wherein said intracorporeal indwelling conduit (Figure 1A) comprising: section far away 2.6～3F conduit 1,2.6～3F and 4F connecting portion 2, nearly section 4F conduit 3.Further, described far away section of 2.6～3F microtubular 1, length 8～12cm, be preferably 10cm, near-end is connected with 4F conduit 3 with 4F connecting portion 2 by 2.6～3F, enter gastroduodenal artery branch right gastroepiploic artery for easier selection, 2.6～3F microtubular 1 can make us needn't seal its stomidium or inner chamber, because the minor axis of the oval side opening 5 of near- end 4F conduit 3 is slightly larger than the overall diameter of 2.6～3F conduit 1, and side opening 5 is out the far-end at 4F conduit 3, instead of open on 2.6～3F conduit 1, in the situation that injection pressure is not very big, namely in the time of common low discharge Intraarterial Chemotherapy, medicine can flow out from side opening 5 completely.Adopt this design, medicine moment flows out more much easier than long and narrow stomidium outflow less through size and that length is 8～12cm through excessive side opening 5, when therefore far-end side opening does not seal, medicine also only flows out from side opening 5, this glyph interflow body dynamics has also obtained fine confirmation in the time of concrete operations.Therefore, inlying catheter system of the present invention does not need far away section of catheter port to carry out any " locked in " operation.
Described 2.6～3F and 4F conduit connecting portion 2, length 1cm, but be also not limited to this length, for connecting far away section of 2.6～3F microtubular 1 and nearly section 4F conduit 3, size is transition gradually, ensures seriality and the compliance of conduit.
Described 4F conduit 3, length 60～80cm, is preferably 70cm, comprises distal metal labelling 4(Mark) 1 of one and side opening.
Described metal M ark4, adopts platinum to be embedded in tube wall, is positioned at the far-end nearside 0.5～2cm of 4F conduit 3, is preferably 1cm place, for accurately locating the position of near-end side opening 5.
Described conduit side opening 5: be oval, open at nearside 2～4mm of 4F conduit 3 far-end Mark4, be preferably 3mm place, the minor axis of oval side opening is slightly larger than 2.6～3F conduit overall diameter, for carrying out perfusion chemotherapy through this side opening 5, also for send 2.6～3F microtubular thromboembolism sealing gastroduodenal artery (the gastroduodenal artery chamber in far-end 2.6～3F conduit outside) through this side opening 5, the offside femoral artery that do not need to puncture is sent into the far gastroduodenal artery in section outside of other microtubular thromboembolism inlying catheter.
The coaxial microtubular of described 2.6～3F (Figure 1B): length is 115～145cm, is preferably 130cm.For the coaxial microtubular operation of side opening 5 turnover row through above-mentioned 4F inlying catheter 3, the gastroduodenal artery chamber in thromboembolism inlying catheter outside, also carries out the thromboembolism of other Gan Wai branches of Hepatic artery, as right gastric artery, paragaster left artery etc. with this microtubular.
Described micro-wire (Fig. 1 C): 0.014～0.018 inch of diameter (0.36～0.46mm), length 180～220cm, be preferably 200cm, be used for selecting gastroduodenal artery, exchange to send into inlying catheter, coordinate microtubular to select the outer arterial branch of liver, inject microcoils, to implement fixing far away section of conduit.
Accompanying drawing 2 is side hole type Hepatic artery medicine box inlying catheter Operation ideograph of the present invention, inlying catheter far-end is placed in branch's right gastroepiploic artery 11 of gastroduodenal artery 10, the gastroduodenal artery 10 in conduit outside adopts turn sealing 13, inlying catheter is played to fixation, side opening is opened on the common hepatic artery place of gastroduodenal artery 10 near-ends simultaneously.Show that from hepatic arteriography Hepatic artery and branch thereof show completely, gastroduodenal artery obturation.
In addition, be connected to the implanted subcutaneous repeated multiple times administration of being convenient to of Hepatic artery chemotherapy medicine box of inlying catheter near-end, because this part is not emphasis of the present invention, do not repeat them here.
One-sided percutaneous approach side hole type tremulous pulse medicine box inlying catheter system of the present invention has following advantage:
1, select 2.6～3F microtubular, make it more easily enter branch's right gastroepiploic artery of gastroduodenal artery for far away section of inlying catheter.
2, the thin chamber of 2.6～3F of inlying catheter section far away, with the modular design of the larger oval side opening of 4F conduit, while making the arterial perfusion of low discharge, chemotherapeutic flows out through side opening completely, and therefore section far away 2.6～3F tube chamber does not need the sealing of row thromboembolism again, save treatment cost, simplify surgical operation step.
3, the design of the oval side opening of inlying catheter, can complete the coaxial microtubular turnover operation through side opening, fixes to do not need again row offside femoral artery puncture to send into sealing and the conduit of gastroduodenal artery outside the capable 2.6～3F conduit of other conduit.
4, far away section of inlying catheter fixing, side opening perfusion design can effectively prevent catheter displacement and arterial occlusion.Section partial fixing far away, in gastroduodenal artery, prevents catheter displacement; Side opening perfusion causes that compared with stomidium perfusion chemotherapy the risk of vascular occlusion reduces, because stomidium reperfusion mode conductor housing is touched blood vessel sidewall more, stimulate damage to cause that the risk of target vessel obturation obviously increases, and side opening reperfusion mode, side opening majority is free in Endovascular, stimulation to vascular wall and damage obviously alleviate, and the risk of secondary vascular occlusion obviously reduces.
5, when this invention obviously makes a variation (in the blood vessel variation situation that proper hepatic artery lacks or proper hepatic artery is very short) for Hepatic artery and Hepatic artery is tortuous, still can ensure the technique successful rate of very high Hepatic artery Medication box implanting, and conventional inlying catheter system majority can not complete in this case.
It should be noted that; the foregoing is only preferred embodiment of the present invention; not thereby limit scope of patent protection of the present invention, the present invention can also carry out to the structure of above-mentioned various parts the improvement of material and structure, or adopts technical equivalents thing to replace.Therefore the equivalent structure that all utilizations description of the present invention and diagramatic content are done changes, or directly or indirectly apply to other correlative technology fields and be all in like manner all contained in the scope that the present invention contains.
Claims (10)
1. a Hepatic artery medicine box inlying catheter system, mainly comprise intracorporeal indwelling conduit, the coaxial microtubular of 2.6～3F and micro-wire, it is characterized in that, described intracorporeal indwelling conduit comprises: section far away 2.6～3F conduit, nearly section 4F conduit, and 2.6～3F and 4F conduit connecting portion, this connecting portion size transition gradually, seriality and the compliance of guarantee conduit; Far-end at 4F conduit is provided with metal marker, on 4F conduit with the spaced apart oval side opening that is provided with of nearside of this metal marker, the minor axis of described oval side opening is slightly larger than the overall diameter of 2.6～3F conduit, and section far away 2.6～3F catheter length is 8～12cm, and its stomidium or inner chamber are without shutoff.
2. Hepatic artery medicine box inlying catheter system according to claim 1, is characterized in that, described 2.6～3F catheter length is 10cm; Section far away 2.6～3F conduit is convenient to enter smoothly right gastroepiploic artery, and does not need closed inner chamber.
3. Hepatic artery medicine box inlying catheter system according to claim 1, it is characterized in that, described side opening is for being oval, and the minor axis of oval side opening is slightly larger than the overall diameter of 2.6～3F conduit, be convenient to medicine and flow out from side opening, be also convenient to the microtubular operation through side opening turnover 2.6～3F.
4. Hepatic artery medicine box inlying catheter system according to claim 1, is characterized in that, the length of described 2.6～3F and 4F conduit connecting portion is made as 1cm.
5. Hepatic artery medicine box inlying catheter system according to claim 1, is characterized in that, described metal marker adopts platinum to be embedded in tube wall, is positioned at far-end nearside 0.5～2cm place of 4F conduit, for accurately locating the position of near-end side opening.
6. Hepatic artery medicine box inlying catheter system according to claim 5, is characterized in that, platinum labelling is positioned at the far-end nearside 1cm place of 4F conduit.
7. Hepatic artery medicine box inlying catheter system according to claim 1, is characterized in that, described side opening is opened the nearside 2～4mm place at 4F distal end of catheter metal marker.
8. Hepatic artery medicine box inlying catheter system according to claim 7, is characterized in that, described side opening is opened the nearside 3mm place at 4F distal end of catheter metal marker.
9. Hepatic artery medicine box inlying catheter system according to claim 1, is characterized in that, the length of described 4F conduit is 60～80cm, is preferably 70cm; The coaxial microtubular of described 2.6～3F, length is 115～145cm; Described micro-wire, diameter 0.36～0.46mm, length 180～220cm.
10. Hepatic artery medicine box inlying catheter system according to claim 9, is characterized in that, the length of the coaxial microtubular of described 2.6～3F is 130cm; The length of micro-wire is 200cm.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410152089.3A CN103877662B (en) | 2014-04-15 | 2014-04-15 | A kind of Hepatic artery medicine box inlying catheter system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410152089.3A CN103877662B (en) | 2014-04-15 | 2014-04-15 | A kind of Hepatic artery medicine box inlying catheter system |
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| CN103877662A true CN103877662A (en) | 2014-06-25 |
| CN103877662B CN103877662B (en) | 2016-03-02 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139361A (en) * | 2016-07-29 | 2016-11-23 | 武汉大学 | A kind of blood vessel guiding catheter and fixing means thereof |
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| US4772266A (en) * | 1987-05-04 | 1988-09-20 | Catheter Technology Corp. | Catheter dilator/sheath assembly and method |
| CN2411014Y (en) * | 1999-12-25 | 2000-12-20 | 徐州医学院肿瘤防治研究所 | Hepatic artery retaining saccule catheter |
| CN2415777Y (en) * | 2000-04-10 | 2001-01-24 | 黄金华 | Multi-side hole introducing chemical therapeutical medicinal box catheter |
| JP2005323813A (en) * | 2004-05-14 | 2005-11-24 | Piolax Medical Device:Kk | Catheter for injecting liquid medicine |
| US20120157854A1 (en) * | 2010-12-15 | 2012-06-21 | Cook Incorporated | System and method for gaining percutaneous access to a body lumen |
| CN203816038U (en) * | 2014-04-15 | 2014-09-10 | 北京市肿瘤防治研究所 | Hepatic artery pillbox indwelling catheter system |
-
2014
- 2014-04-15 CN CN201410152089.3A patent/CN103877662B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772266A (en) * | 1987-05-04 | 1988-09-20 | Catheter Technology Corp. | Catheter dilator/sheath assembly and method |
| CN2411014Y (en) * | 1999-12-25 | 2000-12-20 | 徐州医学院肿瘤防治研究所 | Hepatic artery retaining saccule catheter |
| CN2415777Y (en) * | 2000-04-10 | 2001-01-24 | 黄金华 | Multi-side hole introducing chemical therapeutical medicinal box catheter |
| JP2005323813A (en) * | 2004-05-14 | 2005-11-24 | Piolax Medical Device:Kk | Catheter for injecting liquid medicine |
| US20120157854A1 (en) * | 2010-12-15 | 2012-06-21 | Cook Incorporated | System and method for gaining percutaneous access to a body lumen |
| CN203816038U (en) * | 2014-04-15 | 2014-09-10 | 北京市肿瘤防治研究所 | Hepatic artery pillbox indwelling catheter system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139361A (en) * | 2016-07-29 | 2016-11-23 | 武汉大学 | A kind of blood vessel guiding catheter and fixing means thereof |
| CN106139361B (en) * | 2016-07-29 | 2022-07-19 | 武汉大学 | Blood vessel guiding catheter and fixing method thereof |
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| CN103877662B (en) | 2016-03-02 |
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