CN103892933A - Multifunctional head fixation instrument for murine head and neck operations - Google Patents

Multifunctional head fixation instrument for murine head and neck operations Download PDF

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Publication number
CN103892933A
CN103892933A CN201410115557.XA CN201410115557A CN103892933A CN 103892933 A CN103892933 A CN 103892933A CN 201410115557 A CN201410115557 A CN 201410115557A CN 103892933 A CN103892933 A CN 103892933A
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China
Prior art keywords
vertical shaft
column
cross bar
slide block
fixed
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CN201410115557.XA
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CN103892933B (en
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蒋恩社
靳永萍
范媛媛
皮令阁
冯志芬
于东明
王蕊
田波
李丽
桂影
孟雁平
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Henan University
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Henan University
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Abstract

A multifunctional head fixation instrument for murine head and neck operations is characterized by comprising a base, a column, a slider, a cross rod, a press rod, a vertical shaft and a temperature control system. The column is fixed in the middle of the left end of the upper surface of the base vertically, a rectangular groove is formed on the right side of the column, a rectangular through hole which extends along left and right and corresponds to the rectangular groove is formed in the lower half portion of the column, and a rectangular groove corresponding to the rectangular groove is arranged at the left end of the slider. The multifunctional head fixation instrument is easy and convenient to operate, low in manufacturing cost and small in space occupation and capable of fixing rat heads by cooperation of the cross rod and the press rod; all-side rotation of the rat heads is achieved by rotating the cross rod so that the instrument has full-side operational angle; body temperature of rats in anesthetic states is maintained by means of the temperature control system so that long-time operation can be achieved; operational visual field can be enlarged by a view enlarging system so that operational precision can be improved; components of the instrument are convenient to change due to the bolt connection structures arranged at multiple positions.

Description

Multi-functional muroid head neck operation head fixer
Technical field
The present invention relates to a kind of Mus fixture, relate in particular to a kind of multi-functional muroid head neck operation head fixer.
Background technology
In Neuroscience Research field, in order better to study the function and efficacy of various nerve nucleus in rat or mouse brain, scientific research personnel need to very firmly be fixed up the head of rat or mice, longitudinally cut the skin of head along median line, rely on sutura mark bregma, posterior and the median line of skull to carry out the location of Cerebrum nucleus, then open cranium at anchor point, electrode is placed in to the method injection core group that records neuron electric discharge or micro-medicine is passed through to Cerebrum nucleus micro-injection in core group.Such experimental technique just need to firmly be fixed up the snout of rat and mice and ear both sides, so research worker has just been invented rat and mouse brain stereotaxic instrument, such as, the SR-6R(rat both arms that famous Japanese Cheng Mao (Narishige Group) company produces) type brain solid positioner.Rat brain stereotaxic instrument is by a pair of ear bar, nose and front tooth is clamping determine rat head, and two ear bars are fixed on the U-shaped base of brain solid positioner, and such instrument is very useful and fit closely for the function of studying rat Cerebrum nucleus.Due to the adapter of fixing head can rotate a certain angle (such as,-35 ° ~+35 °) such rat head fixer also can implement some operations of rat buccal portion and cervical region, but owing to there being the obstacle of the ear bar of rat ear both sides and two arms of U-shaped base, the moving range of arm and operating theater instruments while having hindered operation.The operation that utilizes such head fixer to implement buccal portion and cervical region is very inconvenient, nor can implement the operation of ear.For some operations of rat buccal portion, ear and cervical region, the excision of picture cervical region nervus sublingualis, nervus glossopharyngeus cut-out and cervical region body of gland, fixedly not requiring of rat head is very firmly fixing, and very high to the otch of operation area requirement around, the clog-free movement of arm when open scope is convenient to perform a surgical operation.
Existing rat brain stereotaxic instrument is owing to being mainly fixedly securing of head for carrying out some experiments of Cerebrum nucleus, and need other muroid head neck operations of operative incision circle-of-sight visibility broadness for not needing to fixedly secure, existing rat brain stereotaxic instrument has a lot of technical problems and inconvenience for such operation, and existing brain solid positioner is expensive, mostly all more than 20,000 yuan.
Summary of the invention
The defect existing for prior art, the invention provides a kind of multi-functional muroid head neck operation head fixer easy to use and lower-cost.
Concrete technical scheme is: multi-functional muroid head neck operation head fixer, comprise pedestal, column, slide block, cross bar, depression bar, vertical shaft and temperature control system, column is vertically fixed on the centre position of pedestal upper surface left end, column right flank is provided with rectangular recess, column the latter half is provided with the rectangular through-hole of the left and right directions corresponding with rectangular recess, slide block left end is provided with the rectangle projection corresponding with rectangular recess, the rectangle projection of slide block be arranged in rectangular recess and slide block by being fixed on column right flank through the bolt of rectangular through-hole, slide block right side is provided with blind hole, cross bar left end is provided with cylindrical bar, cross bar is inserted in blind hole and by bolt vertical with blind hole on slide block and is fixed by cylindrical bar, vertical shaft is positioned at cylindrical bar right side and vertical shaft lower end vertically through cross bar, vertical shaft lower end is fixed by the bolt perpendicular to vertical shaft on cross bar, cross bar right-hand member is provided with T connector, the position that is positioned at T connector left side on cross bar is provided with manhole, vertical shaft upper end is fixed by the bolt perpendicular to vertical shaft on depression bar through depression bar left end and vertical shaft upper end, depression bar right-hand member is provided with extension item straight down, extend an end and be provided with circular groove, temperature control system is connected to form by heating cushion and temperature controller, heating cushion is arranged at pedestal below.
On described pedestal, be provided with visual field amplification system, comprise base, support and magnifier, base is positioned at pedestal upper surface, and base upper surface is provided with groove, and support is vertically fixed on base, and magnifier is fixed on support upper end.
Described pedestal lower surface is provided with height adjusting support foot.
The present invention is simple to operation, takes up room little, and cost is low, can be fixed Mus head by the cooperation of cross bar and depression bar; Can make a Mus multi-directional rotation by rotary bar, omnibearing work angle is provided; Can make rat under narcotism, still keep body temperature by temperature control system, carry out long hands art; Can amplify surgical field of view by visual field amplification system, improve operation technique precision; The bolt fastening structure of many places makes each part replacement convenient.
Brief description of the drawings
Fig. 1 is structural representation of the present invention;
Fig. 2 is pillar construction schematic diagram of the present invention;
Fig. 3 is Fig. 2 top view;
Fig. 4 is slide block structure schematic diagram of the present invention;
Fig. 5 is Fig. 4 right view;
Fig. 6 is bar structure schematic diagram of the present invention;
Fig. 7 is pressure rod structure schematic diagram of the present invention;
Fig. 8 is Fig. 7 right view;
Fig. 9 is understructure schematic diagram of the present invention.
Detailed description of the invention
As shown in Figure 1, multi-functional muroid head neck operation head fixer, comprise pedestal 1, column 2, slide block 3, cross bar 4, depression bar 5, vertical shaft 6 and temperature control system 7, column 2 is vertically fixed on the centre position of pedestal 1 upper surface left end, as shown in Figures 2 and 3, column 2 right flanks are provided with rectangular recess 8, column the latter half is provided with the rectangular through-hole 9 of the left and right directions corresponding with rectangular recess 8, as shown in Figure 4 and Figure 5, slide block 3 left ends are provided with the rectangle projection 10 corresponding with rectangular recess 8, the rectangle projection 10 of slide block 3 is arranged in rectangular recess 8 and slide block 3 is fixed on column 2 right flanks by the bolt 11 through rectangular through-hole 9, slide block 3 right sides are provided with blind hole 12, as shown in Figure 6, cross bar 4 left ends are provided with cylindrical bar 13, cross bar 4 is inserted in blind hole 12 and by bolt vertical with blind hole 12 on slide block 3 14 and is fixed by cylindrical bar 13, vertical shaft 6 is positioned at cylindrical bar 13 right sides and vertical shaft 6 lower ends vertically through cross bar 4, vertical shaft 6 lower ends are fixing by the bolt 15 perpendicular to vertical shaft 6 on cross bar 4, cross bar 4 right-hand members are provided with T connector 16, the position that is positioned at T connector 16 left sides on cross bar 4 is provided with manhole 17, vertical shaft 6 upper ends are fixing by the bolt 18 perpendicular to vertical shaft 6 on depression bar 5 through depression bar 5 left ends and vertical shaft 6 upper ends, as shown in Figure 7 and Figure 8, depression bar 5 right-hand members are provided with extension item 19 straight down, extend 19 end and be provided with circular groove 20, temperature control system 7 is connected to form by heating cushion 21 and temperature controller 22, heating cushion 21 is arranged at pedestal 1 below.
In the time of operation, first unclamp bolt 11, adjusting slider 3 height, then T connector 16 is inserted in the mouse mouth that needs operation, select the manhole 17 of correct position according to the size of Mus head, the front tooth of mouse is put into manhole 17, unclamp bolt 18, regulate the position of depression bar 5 on vertical shaft 6, make circular groove 20 push down mouse nose, then tight a bolt 18 by fixing depression bar 5, in the time needing to adjust the Mus brilliance in operation process and spend, unclamp bolt 14, obtain different Mus head operation angles by the rotation of cylindrical bar 13, coordinate and can realize Mus 360 ° of rotations by the altitude mixture control of slide block 3 and the rotation of cylindrical bar 13, longer when operating time, for guaranteeing the body temperature of mouse, open temperature control system 7, control heating cushion 21 by temperature controller 22 and generate heat, through the heat transmission of pedestal 1, keep the body temperature of mouse,
Because rat and mice build differ greatly, select the depression bar 5 of different size and corresponding cross bar 4 according to practical situation.
On pedestal 1, be provided with visual field amplification system, comprise base 23, support 24 and magnifier 25, base 23 is positioned at pedestal 1 upper surface, as shown in Figure 9, base 23 upper surfaces are provided with groove 26, can deposit the required instrument of operation, support 24 is vertically fixed on base, magnifier 25 is fixed on support 24 upper ends, and the position by movable base 23 on pedestal 1 utilizes magnifier 25 or obtains surgical field of view more clearly.
Pedestal 1 lower surface is provided with height adjusting support foot 27, can make pedestal 1 held stationary by height adjusting support foot 27.

Claims (3)

1. multi-functional muroid head neck operation head fixer, it is characterized in that: comprise pedestal, column, slide block, cross bar, depression bar, vertical shaft and temperature control system, column is vertically fixed on the centre position of pedestal upper surface left end, column right flank is provided with rectangular recess, column the latter half is provided with the rectangular through-hole of the left and right directions corresponding with rectangular recess, slide block left end is provided with the rectangle projection corresponding with rectangular recess, the rectangle projection of slide block be arranged in rectangular recess and slide block by being fixed on column right flank through the bolt of rectangular through-hole, slide block right side is provided with blind hole, cross bar left end is provided with cylindrical bar, cross bar is inserted in blind hole and by bolt vertical with blind hole on slide block and is fixed by cylindrical bar, vertical shaft is positioned at cylindrical bar right side and vertical shaft lower end vertically through cross bar, vertical shaft lower end is fixed by the bolt perpendicular to vertical shaft on cross bar, cross bar right-hand member is provided with T connector, the position that is positioned at T connector left side on cross bar is provided with manhole, vertical shaft upper end is fixed by the bolt perpendicular to vertical shaft on depression bar through depression bar left end and vertical shaft upper end, depression bar right-hand member is provided with extension item straight down, extend an end and be provided with circular groove, temperature control system is connected to form by heating cushion and temperature controller, heating cushion is arranged at pedestal below.
2. multi-functional muroid head neck operation head fixer as claimed in claim 1, it is characterized in that: on described pedestal, be provided with visual field amplification system, comprise base, support and magnifier, base is positioned at pedestal upper surface, base upper surface is provided with groove, support is vertically fixed on base, and magnifier is fixed on support upper end.
3. multi-functional muroid head neck operation head fixer as claimed in claim 1, is characterized in that: described pedestal lower surface is provided with height adjusting support foot.
CN201410115557.XA 2014-03-26 2014-03-26 Multi-functional muroid head neck operation head fixer Active CN103892933B (en)

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Application Number Priority Date Filing Date Title
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CN103892933B CN103892933B (en) 2015-11-18

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104323869A (en) * 2014-11-22 2015-02-04 浙江中医药大学 Constant-temperature operating table accessory applicable to encephalic implantation rat
CN106017846A (en) * 2016-07-27 2016-10-12 浙江吉利控股集团有限公司 Height measurement assisting tool used for dummy head falling calibration test
CN107468370A (en) * 2017-08-16 2017-12-15 上海药明康德新药开发有限公司 Fixator for continuous acquisition cerebrospinal fluid of rats under narcosis
CN108542539A (en) * 2018-04-23 2018-09-18 佛山市博知盾识科技有限公司 A kind of animal and veterinary surgical console

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040016057A1 (en) * 2000-12-19 2004-01-29 James Traut Head immobilizer
US6698045B1 (en) * 2001-11-02 2004-03-02 Anholt Technologies, Inc. Angling head immobilization device
CN2707296Y (en) * 2004-05-25 2005-07-06 无锡市第四人民医院 Fixer for head radiotherapy
CN201055438Y (en) * 2007-06-28 2008-05-07 北京生命科学研究所 Animal head fixing device with two-dimension regulation function
CN203763289U (en) * 2014-03-26 2014-08-13 河南大学 Multifunctional head fixing apparatus for operations on heads and necks of mice

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040016057A1 (en) * 2000-12-19 2004-01-29 James Traut Head immobilizer
US6698045B1 (en) * 2001-11-02 2004-03-02 Anholt Technologies, Inc. Angling head immobilization device
CN2707296Y (en) * 2004-05-25 2005-07-06 无锡市第四人民医院 Fixer for head radiotherapy
CN201055438Y (en) * 2007-06-28 2008-05-07 北京生命科学研究所 Animal head fixing device with two-dimension regulation function
CN203763289U (en) * 2014-03-26 2014-08-13 河南大学 Multifunctional head fixing apparatus for operations on heads and necks of mice

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104323869A (en) * 2014-11-22 2015-02-04 浙江中医药大学 Constant-temperature operating table accessory applicable to encephalic implantation rat
CN104323869B (en) * 2014-11-22 2016-03-23 浙江中医药大学 Be applicable to the constant operation table accessory that intracranial implants rat
CN106017846A (en) * 2016-07-27 2016-10-12 浙江吉利控股集团有限公司 Height measurement assisting tool used for dummy head falling calibration test
CN107468370A (en) * 2017-08-16 2017-12-15 上海药明康德新药开发有限公司 Fixator for continuous acquisition cerebrospinal fluid of rats under narcosis
CN108542539A (en) * 2018-04-23 2018-09-18 佛山市博知盾识科技有限公司 A kind of animal and veterinary surgical console

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