CN104414672B - PET imaging method, PET imaging and molybdenum target fusion imaging device and method - Google Patents
PET imaging method, PET imaging and molybdenum target fusion imaging device and method Download PDFInfo
- Publication number
- CN104414672B CN104414672B CN201310577087.4A CN201310577087A CN104414672B CN 104414672 B CN104414672 B CN 104414672B CN 201310577087 A CN201310577087 A CN 201310577087A CN 104414672 B CN104414672 B CN 104414672B
- Authority
- CN
- China
- Prior art keywords
- pet
- breast
- molybdenum target
- solid
- state
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/44—Constructional features of apparatus for radiation diagnosis
- A61B6/4417—Constructional features of apparatus for radiation diagnosis related to combined acquisition of different diagnostic modalities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computerised tomographs
- A61B6/037—Emission tomography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
- A61B6/4208—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
- A61B6/4258—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
- A61B6/4266—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a plurality of detector units
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
- G01T1/161—Applications in the field of nuclear medicine, e.g. in vivo counting
- G01T1/1611—Applications in the field of nuclear medicine, e.g. in vivo counting using both transmission and emission sources sequentially
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/29—Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
- G01T1/2914—Measurement of spatial distribution of radiation
- G01T1/2985—In depth localisation, e.g. using positron emitters; Tomographic imaging (longitudinal and transverse section imaging; apparatus for radiation diagnosis sequentially in different planes, steroscopic radiation diagnosis)
Abstract
The invention discloses a PET imaging and molybdenum target X ray fusion imaging device aiming at breast and lymph. The device comprises a molybdenum target X ray tube, a high pressure generator, an X ray detector, two groups of PET detector systems, a data acquiring module, a mechanical moving system, a control system, a data transmitting system and a data processing server, wherein the two groups of PET detector systems form a non-annular detecting structure. The invention also discloses a PET imaging and molybdenum target X ray fusion imaging method, wherein a molybdenum target scanned image is obtained by molybdenum target X ray scanning; a PET image is obtained by PET scanning; subsequently, the molybdenum target scanned image and the PET image are analyzed and processed to obtain a molybdenum target and PET fusion image. According to the method and the device disclosed by the invention, the PET detector systems which are of a non-annular detecting structure are integrated with a molybdenum target breast X ray system, so that the use of a clinical PET system which is of an annular structure is avoided, and thus the performance is improved, the cost is lowered, and promotion and application of the technology are relatively facilitated.
Description
Technical field
The present invention relates to medical imaging field is and in particular to a kind of PET for mammary gland and lymph is imaged and molybdenum target X-ray
Fusion of imaging device and method, this device and method needs PET to become with molybdenum target X-ray be applied to medical imaging with diagnostic field
As system mammary gland and lymph are scanned and fusion of imaging application scenario.
Background technology
For a long time, cancer is considered incurable disease, and people talk cancer complexion changed.Breast carcinoma is women common malignum multiplex tumor
One of, very harmful.Positron emission fault（PositronEmissionTomography, all abbreviation PET in full）As one
Plant new Image Examination, be with the difference in tumor tissues metabolism, diagnosis to be made to tumor using normal structure.Due to
It has higher sensitivity and specificity, is that the hurtless measure diagnosis of breast carcinoma provides opportunity, and can be to the treatment of breast carcinoma
Enter Mobile state to observe, the selection for therapeutic scheme provides foundation；On the other hand, PET in the follow up of breast carcinoma can and
Early find recurrence and the transfer of tumor.Clinical research proves, PET examines to breast carcinoma primary tumo(u)r and the qualitative of axillary gland
The etiologic diagnosis break, recurring and shifting and the judgement for the treatment of curative effect are all significant.But because PET cannot provide dissection
Imaging, it is impossible to carry out accurate structure positioning to tumor, limits its development.
Breast X-ray machine camera work, through the development of decades, is currently the only being approved by the fda in the United States for mammary gland
The inspection method of cancer examination.Particularly breast molybdenum target machine, has high level density resolution, and photographic image definition is good, instead
Difference is big, high resolution, can show structure and the disorder of each hierarchical organization of mammary gland, finds minute lesion；0.8cm can be found even more
Little tumor is simultaneously told good, pernicious, is diagnosis and most effective, the most accurate, the most reliable means finding breast carcinoma of early stage, and
And have the advantages that economy, easily and fast, patient be not subject to misery.
PET imaging technique is combined with molybdenum target breast X-ray imaging technique, can have complementary advantages, accurately obtain breast
The functional activity information at gland position and anatomical information, and realize breast carcinoma primary tumo(u)r and the qualitative of axillary gland is examined
Etiologic diagnosis that are disconnected, recurring and shift, tool is of great significance.
At present, molybdenum target breast X-ray system generally all adopts flat board detecting structure, and it is located at front, and breast is squeezed
It is imaged after pressure positioning, and PET imaging technique is limited to imaging algorithm, generally adopts annular detection structure, the PET of little ring is visited
Survey device system and cannot carry out integrated with the molybdenum target breast X-ray system of flat board, and whole mammary gland part can not be covered simultaneously, real
Existing both are imaged simultaneously, and meanwhile, little its visual field of ring-shaped P ET system cannot completely cover axillary gland, just cannot
Axillary gland is imaged.And although PET system and molybdenum target mammary gland X can be penetrated when using clinical whole body PET system
Linear system system carry out integrated, but due to PET, to detect ring diameter too big, leads to its spatial resolution and system sensitivity to deteriorate, meeting
Reduce PET system image quality, the too high cost of clinical PET, also limit its popularization and application simultaneously.
Therefore, for above-mentioned technical problem it is necessary to propose a kind of PET imaging for mammary gland and lymph of new structure
With molybdenum target X-ray fusion of imaging device and method.
Content of the invention
In view of this, it is an object of the invention to provide a kind of high-performance, low cost become with the PET of lymph for mammary gland
Picture and molybdenum target fusion of imaging devices and methods therefor.
For achieving the above object, the present invention provides following technical scheme：
A kind of PET imaging and molybdenum target fusion of imaging device, it include tube with Mo target,x-ray, high tension generator, X-ray detector,
Two groups of Solid-state pet detector system, data acquisition module, frame, mechanism system, control system, data transmission system datas
Processing server, described tube with Mo target,x-ray forms molybdenum target scanning system, described each group of Solid-state pet detector system with X-ray detector
It is made up of at least one detector module, described two groups of Solid-state pet detector system form an other than ring type detecting structure.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, by one in described every group of Solid-state pet detector system
Individual or multiple detector module compositions, arrange as regular plane or continuous curved surface or do not connect in the surface of whole detector system
Continuous flat board or discontinuous curved surface.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described every group of Solid-state pet detector system mutually it
Between the detector module number, the surface arrangement mode of detector module, the size of detector system and the detector system that comprise
Performance consistent.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described every group of Solid-state pet detector system mutually it
Between the detector module number, the surface arrangement mode of detector module, the size of detector system and the detector system that comprise
Performance all inconsistent or partly consistent.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described every group of detector system is transported by machinery
Dynamic system carries out self-movement.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, the spacing of described two groups of Solid-state pet detector system
Change is moved by mechanism system, described spacing range is 5cm-80cm.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described two groups of Solid-state pet detector system, one group of position
In the front of human chest, another group of rear being located at human body back.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described device is applied to mammary gland and lymph, institute
State the breast immobilization device that device also includes coordinating frame breast to be wrapped up and is fixed, described breast immobilization device is by density
Relatively low material composition.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described frame is vertical or horizontal, and should
Frame is fixed or packaged type.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described tube with Mo target,x-ray is molybdenum target mammary gland molybdenum
Target X-ray tube.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described molybdenum target scanning system is located at human chest
Front side, described tube with Mo target,x-ray and X-ray detector adjust spacing between the two by mechanism system.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described data transmission system adopts wire transmission
Mode or wireless transmission method.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging device, described mechanism system is to be by control
System is automatically controlled, or directly manually controls, or is controlled by automatically and manually mixing.
A kind of PET imaging and molybdenum target fusion of imaging method, it includes step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to one or two fixation
Breast, and can cover whole breast, provides two groups of claim 1-8 arbitrary described Solid-state pet detector system, by one group
Solid-state pet detector system is placed in the front portion of this or two fixing breast, by another set Solid-state pet detector system be placed in this one
Only or two fixing breast correspondence backs rear portion, and adjust two groups of detector systems so as to whole breast can be covered
Room；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by one
Data collecting system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and passes through a data transmission system
System is transferred to a data processing server and is processed, and obtains molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
Preferably, above-mentioned PET imaging and molybdenum target fusion of imaging method in, by a breast immobilization device to human body one
Only or two breast are fixed.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging method, system is controlled by a mechanism system or one
System or Non-follow control adjust the spacing between tube with Mo target,x-ray and X-ray detector.
Preferably, in above-mentioned PET imaging and molybdenum target fusion of imaging method, PET image is 2D or 3D rendering.
A kind of PET imaging method, it includes step：
The position of fixing human；
Two groups of any of the above-described described Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved to human body one
The front portion of lymph node near breast, another set Solid-state pet detector system is moved to this breast corresponding rear portion of lymph node nearby,
And adjust two groups of detector systems so as to this lymph node can be covered；
This lymph node is carried out concentrate PET scan, and by data collecting system, the PET scan data obtaining is adopted
Collection, data is transferred to a data processing server by a data transmission system and is processed, obtain PET image.
A kind of PET imaging method, it includes step：
The position of fixing human；
Two groups of any of the above-described described Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved to human body one
Or two breast and its front portion of neighbouring lymph node, another set Solid-state pet detector system is moved to this or two
Breast and its corresponding rear portion of neighbouring lymph node, and adjust two groups of detector systems so as to can cover this or
Two breast and its neighbouring lymph node；
PET scan is carried out to this or two breast and its neighbouring lymph node, and by data collecting system to
To PET scan data be acquired, data is transferred at a data processing server by a data transmission system
Reason, obtains PET image.
From technique scheme as can be seen that the embodiment of the present invention passes through the pet detector using other than ring type detecting structure
System and molybdenum target breast X-ray system carry out integrated, it is to avoid using the clinical PET system of loop configuration, improve performance, reduce
Cost, advantageously in the popularization and application of technology.
Brief description
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
Have technology description in required use accompanying drawing be briefly described it should be apparent that, below describe in for the present invention
Accompanying drawing is only some embodiments of the present invention, for those of ordinary skill in the art, is not paying creative work
Under the premise of, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the flow chart of PET of the present invention imaging and molybdenum target X-ray fusion of imaging method；
Fig. 2 is a kind of flow chart of the PET imaging method only lymph node being scanned of the present invention；
Fig. 3 is that the PET that present invention another kind is scanned to or two breast and its neighbouring lymph node simultaneously becomes
The flow chart of image space method；
Fig. 4 is the element architecture figure of PET of the present invention imaging and molybdenum target X-ray fusion of imaging device.
Specific embodiment
The invention discloses the PET imaging for mammary gland and lymph of a kind of high-performance, low cost and molybdenum target X-ray merge
Imaging device and method.
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is retouched in detail
State it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the present invention
In embodiment, the every other enforcement that those of ordinary skill in the art are obtained on the premise of not making creative work
Example, broadly falls into the scope of protection of the invention.
As shown in figure 4, PET imaging disclosed by the invention and molybdenum target fusion of imaging device are applied to mammary gland and lymph, its bag
Include tube with Mo target,x-ray, high tension generator, X-ray detector, two groups of Solid-state pet detector system, data acquisition module, frame, machinery fortune
Dynamic system, control system, breast immobilization device, data transmission system data processing server, described tube with Mo target,x-ray and X penetrate
Line detector forms molybdenum target scanning system, and described each group of Solid-state pet detector system is made up of at least one detector module.Described
Two groups of Solid-state pet detector system form an other than ring type detecting structure.The present invention passes through the detecting structure using other than ring type, it is to avoid make
With the clinical PET system of loop configuration, improve performance, reduce cost.
Described Solid-state pet detector system one of which is located at the front of human chest, another group of rear being located at human body back.
Described molybdenum target scanning system is located on front side of human chest, and described tube with Mo target,x-ray and X-ray detector are adjusted by mechanism system
Section spacing between the two.Described breast immobilization device is included by the relatively low material composition of density, materials of low density：Polyethylene,
Polypropylene, polrvinyl chloride, polyether-ether-ketone etc..Described breast immobilization device can coordinate frame, breast is wrapped up and is fixed,
Ensure in scanning process, breast will not be subjected to displacement and deformation.
It is made up of one or more detector modules in described every group of Solid-state pet detector system, the table of whole detector system
Arrange as regular plane or continuous curved surface or discontinuous flat board or discontinuous curved surface in face.
The detector module number that described every group of Solid-state pet detector system comprises each other, the surface of detector module are arranged
Mode for cloth, the size of detector system are consistent with the performance of detector system.Certainly, described every group of Solid-state pet detector system is mutual
Between the detector module number, the surface arrangement mode of detector module, the size of detector system and the detector system that comprise
The performance of system is all inconsistent or partly consistent.
The temporal resolution of Solid-state pet detector system of the present invention is 50ps-50ns.
Described every group of detector system carries out self-movement by mechanism system.
The spacing of described two groups of Solid-state pet detector system moves change by mechanism system, described spacing range
For 5cm-80cm.
Described frame is vertical or horizontal, and this frame is fixed or packaged type.
Described tube with Mo target,x-ray is molybdenum target mammary gland tube with Mo target,x-ray.
Described data transmission system can adopt wire transmission mode, and such as Ethernet, USB, serial communication etc. is it is also possible to adopt
With wireless transmission method, such as 802.11a, bluetooth, Zigbee etc..
Described mechanism system can be to be automatically controlled it is also possible to be controlled manually by control system,
Can automatically and manually mix and be controlled.
As shown in figure 1, PET imaging disclosed by the invention and molybdenum target fusion of imaging method, it includes step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to one or two fixation
Breast, and can cover whole breast, provides two groups of claim 1-8 arbitrary described Solid-state pet detector system, by one group
Solid-state pet detector system is placed in the front portion of this or two fixing breast, by another set Solid-state pet detector system be placed in this one
Only or two fixing breast correspondence backs rear portion, and adjust two groups of detector systems so as to whole breast can be covered
Room；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by one
Data collecting system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and passes through a data transmission system
System is transferred to a data processing server and is processed, and obtains molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
From above technical scheme, the method for the present invention can be scanned imaging it is also possible to simultaneously to a breast
Two breast are scanned be imaged.
In said method technical scheme, the two groups of Solid-state pet detector system providing have above-mentioned PET imaging and molybdenum target X-ray
All Solid-state pet detector system features of narration in fusion of imaging device.
Knowable to technique scheme, molybdenum target X-ray scanning and PET scan can be carried out simultaneously, also can separately carry out, tool
The embodiment of body is expressed as follows.
First carry out molybdenum target X-ray scanning, then carry out the concrete grammar step of PET scan be：
S1：The position of one of fixing human or two breast；
S2：Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to this or two
Fixing breast, and whole breast can be covered；
S3：Molybdenum target X-ray scanning is carried out to the breast of this one or two fixation, its data passes through a data acquisition system
System is acquired, and is transferred to data processing server by a data transmission system and is processed, and obtains the scanning of molybdenum target system
Image；
S4：Tube with Mo target,x-ray and X-ray detector are removed；
S5：Two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved to one or two breast
Front portion, another set Solid-state pet detector system is moved to the rear portion at this or two breast correspondence back, and adjusts two
Group detector system is so as to this breast can be covered；
S6：PET scan is carried out to this or two breast, and by data collecting system to the PET scan obtaining
Data is acquired, and data is transferred to data processing server by data transmission system is processed, and obtains PET figure
Picture；
S7：Two groups of Solid-state pet detector system are removed；
S8：Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
First carry out PET scan, then carry out the concrete grammar step of molybdenum target X-ray scanning be：
S1：The position of one of fixing human or two breast；
S2：Two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved to one or two fixation
The front portion of breast, another set Solid-state pet detector system is moved to the rear portion at this or two breast correspondence back, and
Adjust two groups of detector systems so as to whole breast can be covered；
S3：PET scan is carried out to this or two breast, and by data collecting system to the PET scan obtaining
Data is acquired, and data is transferred to a data processing server by a data transmission system and is processed, and obtains PET figure
Picture；
S4：Two groups of Solid-state pet detector system are removed；
S5：Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to this or two
Fixing breast, and whole breast can be covered；
S6：Molybdenum target X-ray scanning is carried out to the breast of this one or two fixation, its data passes through data collecting system
It is acquired, and is transferred to data processing server by data transmission system being processed, obtain molybdenum target system scanogram；
S7：Tube with Mo target,x-ray and X-ray detector are removed；
S8：Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
Carry out molybdenum target X-ray scanning simultaneously and the concrete grammar step of PET scan is：
S1：The position of one of fixing human or two breast；
S2：Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both solid close proximity to one or two
Fixed breast, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved
To the front portion of the breast of this one or two fixation, another set Solid-state pet detector system is moved to this or two
The rear portion at the corresponding back of breast, and adjust two groups of detector systems so as to this or two breast can be covered；
S3：Molybdenum target X-ray scanning and PET scan are carried out to this or two breast simultaneously, and pass through data acquisition
System is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and the data obtaining is passed through a data biography
Defeated system transfers are processed to a data processing server, obtain molybdenum target system scanogram and PET image；
S4：Tube with Mo target,x-ray and X-ray detector are removed, two groups of Solid-state pet detector system are removed；
S8：Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
In said method step, if remove tube with Mo target,x-ray, X-ray detector and two groups of Solid-state pet detector system according to reality
Depending on the situation of border, in practical operation, it is of course also possible to not remove tube with Mo target,x-ray, X-ray detector and two groups of pet detector
System, the description of above-mentioned steps can not limit protection scope of the present invention, and any obvious conversion is all the present invention's
Within protection domain.
In said method step, particular by a breast immobilization device, one of human body or two breast are carried out solid
Fixed.
In said method step, visit particular by a control system or Non-follow control adjustment tube with Mo target,x-ray and X-ray
Survey the spacing between device.Spacing between the two can also be adjusted by above-mentioned mechanism system.
In said method step, the PET image obtaining is 2D or 3D rendering.
Two groups of Solid-state pet detector system mentioned by the present invention can also be scanned to the lymph node near breast being imaged,
Concrete imaging method has three kinds, and a kind of situation is that the lymph being individually moved side carries out being concentrated into picture, and a kind of situation is simultaneously
Cover a breast and the lymph of side is imaged, a kind of situation is to cover two breast to be become with the lymph of both sides simultaneously
Picture.Ginseng is following in detail for concrete grammar description.
As shown in Fig. 2 the invention also discloses a kind of PET imaging method, the method can be to certain breast of human body near
Lymph node carry out concentrate scanning, finally obtain image.Concretely comprise the following steps：
S1：The position of fixing human；
S2：Two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system are moved to and drenches near one breast of human body
The front portion fawned on, another set Solid-state pet detector system is moved to this breast corresponding rear portion of lymph node nearby, and adjusts two
Group detector system is so as to this lymph node can be covered；
S3：This lymph node is carried out concentrate PET scan, and by data collecting system, the PET scan data obtaining is entered
Row collection, data is transferred to a data processing server by a data transmission system and is processed, obtain PET image.
As shown in figure 3, the invention also discloses a kind of PET imaging method, the method can to certain breast of human body and its
Neighbouring lymph node is scanned, and finally obtains image；Can also be simultaneously to the lymph node near two breast and each breast
It is scanned, finally obtain image.Concrete grammar step is：
The position of fixing human；
Two groups of any of the above-described described Solid-state pet detector system are provided, one group of Solid-state pet detector system is moved to human body one
Or two breast and its front portion of neighbouring lymph node, another set Solid-state pet detector system is moved to this or two
Breast and its corresponding rear portion of neighbouring lymph node, and adjust two groups of detector systems so as to can cover this or
Two breast and its neighbouring lymph node；
PET scan is carried out to this or two breast and its neighbouring lymph node, and by data collecting system to
To PET scan data be acquired, data is transferred at a data processing server by a data transmission system
Reason, obtains PET image.
In said method technical scheme, the two groups of Solid-state pet detector system providing have above-mentioned PET imaging and molybdenum target X-ray
All Solid-state pet detector system features of narration in fusion of imaging device.
From technique scheme as can be seen that the embodiment of the present invention PET imaging and molybdenum target X-ray fusion of imaging device and
Method is integrated by being carried out using the Solid-state pet detector system of other than ring type detecting structure and molybdenum target breast X-ray system, it is to avoid use
The clinical PET system of loop configuration, improves performance, reduces cost, advantageously in the popularization and application of technology.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.Any reference in claim should not be considered as limiting involved claim.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment only wraps
Containing an independent technical scheme, only for clarity, those skilled in the art should for this narrating mode of description
Using description as an entirety, the technical scheme in each embodiment can also form those skilled in the art through appropriately combined
Understandable other embodiment.
Claims (10)
1. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, and Solid-state pet detector system described in two groups forms an other than ring type detecting structure；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
2. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, and Solid-state pet detector system described in two groups forms an other than ring type detecting structure, whole
Arrange as regular plane or continuous curved surface or discontinuous flat board or discontinuous curved surface in the surface of individual detector system；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
3. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, and Solid-state pet detector system described in two groups forms an other than ring type detecting structure, often
Detector module number that Solid-state pet detector system described in one group comprises each other, the surface arrangement mode of detector module,
The size of Solid-state pet detector system is consistent with the performance of Solid-state pet detector system；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
4. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, and Solid-state pet detector system described in two groups forms an other than ring type detecting structure, often
Detector module number that Solid-state pet detector system described in one group comprises each other, the surface arrangement mode of detector module,
The size of Solid-state pet detector system is all inconsistent with the performance of Solid-state pet detector system or partly consistent；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
5. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, and Solid-state pet detector system described in two groups forms an other than ring type detecting structure, often
Described in one group, Solid-state pet detector system carries out self-movement by mechanism system；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
6. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, one other than ring type detecting structure of Solid-state pet detector system composition described in two groups, and two
The spacing organizing described Solid-state pet detector system moves change by mechanism system, and described spacing range is 5cm-80cm；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
7. a kind of PET imaging and molybdenum target fusion of imaging method it is characterised in that：Including step：
The position of one of fixing human or two breast；
Spacing between adjustment tube with Mo target,x-ray and X-ray detector, makes both close proximity to the breast of one or two fixation
Room, and whole breast can be covered, two groups of Solid-state pet detector system are provided, one group of Solid-state pet detector system is placed in this
Or the front portion of two fixing breast, another set Solid-state pet detector system is placed in this or two fixing breast and corresponds to
The rear portion at back, and adjust two groups of Solid-state pet detector system so as to whole breast can be covered；PET described in each group detects
Device system is made up of at least one detector module, one other than ring type detecting structure of Solid-state pet detector system composition described in two groups, and two
Organize described Solid-state pet detector system, one group of front being located at human chest, another group of rear being located at human body back；
Molybdenum target X-ray scanning and PET scan are carried out to the breast of this one or two fixation simultaneously or successively, by a data
Acquisition system is acquired to the molybdenum target X-ray scanning data obtaining and PET scan data, and is passed by a data transmission system
Defeated processed to a data processing server, obtain molybdenum target system scanogram and PET image；
Molybdenum target scanogram and PET image are analyzed and process, obtain the fusion image of molybdenum target and PET.
8. according to described PET imaging arbitrary in claim 1-7 and molybdenum target fusion of imaging method it is characterised in that：By one
Breast immobilization device is fixed to one of human body or two breast.
9. according to described PET imaging arbitrary in claim 1-7 and molybdenum target fusion of imaging method it is characterised in that：By one
Mechanism system or a control system or Non-follow control adjust the spacing between tube with Mo target,x-ray and X-ray detector.
10. according to described PET imaging arbitrary in claim 1-7 and molybdenum target fusion of imaging method it is characterised in that：PET schemes
Picture is 2D or 3D rendering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310577087.4A CN104414672B (en) | 2013-08-24 | 2013-11-15 | PET imaging method, PET imaging and molybdenum target fusion imaging device and method |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310373141 | 2013-08-24 | ||
| CN2013103731413 | 2013-08-24 | ||
| CN201310577087.4A CN104414672B (en) | 2013-08-24 | 2013-11-15 | PET imaging method, PET imaging and molybdenum target fusion imaging device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104414672A CN104414672A (en) | 2015-03-18 |
| CN104414672B true CN104414672B (en) | 2017-02-08 |
Family
ID=52585466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310577087.4A Active CN104414672B (en) | 2013-08-24 | 2013-11-15 | PET imaging method, PET imaging and molybdenum target fusion imaging device and method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN104414672B (en) |
| WO (1) | WO2015027568A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113064363B (en) * | 2020-01-02 | 2022-06-24 | 辽宁开普医疗系统有限公司 | Method and system for realizing 2.4G/5G communication mode of portable X-ray medical equipment |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451789A (en) * | 1993-07-19 | 1995-09-19 | Board Of Regents, The University Of Texas System | High performance positron camera |
| CN102448375A (en) * | 2009-04-13 | 2012-05-09 | 霍罗吉克公司 | Integrated breast x-ray and molecular imaging system and method |
| CN103190929A (en) * | 2013-03-23 | 2013-07-10 | 明峰医疗系统股份有限公司 | PEM (Photoelectromagnetic Effect) detector device |
| CN203677113U (en) * | 2013-08-24 | 2014-07-02 | 苏州瑞派宁科技有限公司 | PET (positron emission tomography) molybdenum target X-ray fusion imaging device |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5519221A (en) * | 1992-01-22 | 1996-05-21 | Ansel M. Schwartz | Dedicated apparatus and method for emission mammography |
| US20030194050A1 (en) * | 2002-04-15 | 2003-10-16 | General Electric Company | Multi modality X-ray and nuclear medicine mammography imaging system and method |
| US20060074287A1 (en) * | 2004-09-30 | 2006-04-06 | General Electric Company | Systems, methods and apparatus for dual mammography image detection |
| EP2091434B1 (en) * | 2006-12-11 | 2019-07-17 | Mayo Foundation For Medical Education And Research | System and method for quantitative molecular breast imaging |
| JP2009183448A (en) * | 2008-02-06 | 2009-08-20 | Shimadzu Corp | Diagnostic system |
| JP5806448B2 (en) * | 2009-05-13 | 2015-11-10 | 株式会社東芝 | Nuclear medicine imaging apparatus, image processing apparatus, and image processing method |
| US9322929B2 (en) * | 2011-04-21 | 2016-04-26 | Kabushiki Kaisha Toshiba | PET imaging system including detector elements of different design and performance |
| US9445770B2 (en) * | 2011-07-28 | 2016-09-20 | Shimadzu Corporation | Nuclear medicine diagnostic apparatus |
| EP2747653B1 (en) * | 2011-10-24 | 2016-08-24 | University of Washington through its Center for Commercialization | Positron emission tomography systems for use with mammography machines and associated devices and methods |
-
2013
- 2013-11-13 WO PCT/CN2013/086998 patent/WO2015027568A1/en active Application Filing
- 2013-11-15 CN CN201310577087.4A patent/CN104414672B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451789A (en) * | 1993-07-19 | 1995-09-19 | Board Of Regents, The University Of Texas System | High performance positron camera |
| CN102448375A (en) * | 2009-04-13 | 2012-05-09 | 霍罗吉克公司 | Integrated breast x-ray and molecular imaging system and method |
| CN103190929A (en) * | 2013-03-23 | 2013-07-10 | 明峰医疗系统股份有限公司 | PEM (Photoelectromagnetic Effect) detector device |
| CN203677113U (en) * | 2013-08-24 | 2014-07-02 | 苏州瑞派宁科技有限公司 | PET (positron emission tomography) molybdenum target X-ray fusion imaging device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104414672A (en) | 2015-03-18 |
| WO2015027568A1 (en) | 2015-03-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104545976B (en) | Computer body layer photographing method and device | |
| CN100479757C (en) | Radiography apparatus and radiography method | |
| CN101884545B (en) | Nuclear medical imaging apparatus, image processing apparatus, and image processing method | |
| US20070223651A1 (en) | Dual modality mammography device | |
| US20030202629A1 (en) | Computed tomography system with integrated analogic computer | |
| US9361726B2 (en) | Medical image diagnostic apparatus, medical image processing apparatus, and methods therefor | |
| CN111566705B (en) | System and method for determining a region of interest in medical imaging | |
| JP2014138908A (en) | CT device and method based on motion compensation | |
| CN101401725B (en) | Patient treatment using a hybrid imaging system | |
| US11529108B2 (en) | Methods and apparatus for improving the image resolution and sensitivity of whole-body positron emission tomography (PET) imaging | |
| JP2007089674A (en) | Shape of appearance measuring apparatus and x-ray ct apparatus | |
| KR20140058045A (en) | Radiation imaging apparatus and control method thereof | |
| CN109480883A (en) | Medical diagnostic imaging apparatus | |
| CN102440788A (en) | Stereoscopic image displaying method and device | |
| KR102324192B1 (en) | Medical imaging apparatus and control method for the same | |
| CN104414672B (en) | PET imaging method, PET imaging and molybdenum target fusion imaging device and method | |
| TWI494086B (en) | Data processing device for medical treatment and radiation tomography device having the same | |
| CN105662354A (en) | Wide-viewing-angle optical molecular tomography navigation system and method | |
| JP2013088386A (en) | Medical data processing apparatus and radiation tomography apparatus including the same | |
| CN201591544U (en) | Prone positive electron emitting imaging equipment for diagnosing breast cancer | |
| JP2019037576A (en) | Breast imaging device, image processor and image processing method | |
| JP5541005B2 (en) | Radiation tomography equipment | |
| CN103961124A (en) | Combined diagnosis system integrating PET-CT functions | |
| CN203483445U (en) | Orthopaedic foot CBCT device | |
| WO2019108867A1 (en) | System and method for ultrasonic tissue screening |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |