CN104414826A - Integrated feeling-balance-motion training device for rats with brain injury - Google Patents
Integrated feeling-balance-motion training device for rats with brain injury Download PDFInfo
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- CN104414826A CN104414826A CN201310413625.6A CN201310413625A CN104414826A CN 104414826 A CN104414826 A CN 104414826A CN 201310413625 A CN201310413625 A CN 201310413625A CN 104414826 A CN104414826 A CN 104414826A
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Abstract
The invention discloses an integrated feeling-balance-motion training device for rats with brain injury. The device comprises an outer frame bracket, a console and a plurality of training cages, wherein the console is connected to the outer side of the outer frame bracket; the training cages are arranged abreast in the outer frame bracket, and comprise at least one forward and backward balance training cage and at least one leftward and rightward balance training cage; a treadmill is arranged in each training cage; a forward and backward swinging regulation mechanism is arranged below the forward and backward balance training cage; a leftward and rightward swinging regulation mechanism is arranged below the leftward and backward balance training cage; the console is electrically connected with each treadmill, the forward and backward balance regulation mechanism and the leftward and rightward swinging regulation mechanism. The device can be used for simplex treadmill training and implementing a feeling-balance-motion multifunctional habilitation training mode, the experimental requirements of a researcher can be met, and an advanced animal experiment means can be provided for researches on the neural mechanism rehabilitation of brain injury diseases.
Description
Technical field
The present invention relates to a kind of medical science analogue experiment installation, particularly a kind of brain injury in rats sensation-balance-motion integrated training devices.
Background technology
Brain injury comprises apoplexy, is common clinical disease, and sickness rate is high, mortality rate is high, disability rate is high and cure rate is low, and its high disability rate causes great burden to patient, family and society.Clinical experiment confirms, the motion of sensation one balance one waits rehabilitation therapy can improve brain injury sequela patient locomotor activity, but its neuromechanism is still not clear, and this hinders the development of rehabilitation medicine to a certain extent.Human experimentation is subject to the restriction of methodology and moral aspect, has larger limitation, very it may be necessary zoopery research.Rat is similar to the gene of the mankind, rat is used to carry out the experiment of simulation physiological pathology of human body state, study the effect of various intervention or rehabilitation means and mechanism, having extremely important effect to the essence and rehabilitation being familiar with disease, is the important means promoting clinical breakthrough.
Domestic and international existing many runways laboratory animal treadmill, U.S. Exer-3/6 animal testing running platform etc., but its function singleness, can only carry out motor function training, and namely post-stroke carries out Aerobic Exercise Training is not in early days inconsistent clinical status.In clinical rehabilitation treatment, apoplexy early stage patient cannot complete active exercise, and therapist gives outside passive manipulation, also often allows the material of limbs of patient friction, touch, the different feel of impression and quality, it is trained to distinguish object ability, to promote that its sensory function is recovered.Treat that patient's muscular strength and sensory function are recovered to some extent, after independently standing, because its muscular strength still can not meet motion needs, therefore first give balance function training, comprise balance plate training etc.After patient's muscular strength recovers further, patient is just allowed to carry out active exercise training.For rehabilitation of stroke patients treatment, the theory of modern rehabilitation, not only for the improvement of motor function, also needs the improvement comprising sense of touch and static sense.Impercipience is fed back, and patient is difficult to normally regulable control motion, maintains posture and keep balance.Feel in the training process, to balance and training can not be well-separated, the concept that sensation one balances a training integration must be set up.
Therefore, research and develop a kind of novel multi-functional rat device for healing and training meeting modern rehabilitation medicine theory, the training such as sense culture, balance function training, motor function for rat or other animals is significant.Multi-functional rat device for healing and training both can carry out single treadmill training, sensation one can be implemented again balance an exercise rehabilitation training method and combine, simulate the multifunction rehabilitation training pattern feeling balance one motion clinically truly, can also experimentally require flexibly to select velocity, sway velocity, training time etc., quantize training burden, meet the experiment demand of researcher, the neuromechanism rehabilitation research that the sensation one for brain injury disease balances a motion and combination treatment thereof provides advanced zoopery means.
Summary of the invention
Object of the present invention, is just to solve the problem, and provides a kind of brain injury in rats sensation-balance-motion integrated training devices.
The object of the present invention is achieved like this: a kind of brain injury in rats sensation-balance-motion integrated training devices, comprise outer gimbal support, control station and multiple training cage, control station is connected to the outside of outer gimbal support, multiple training cage is arranged in outer gimbal support side by side, multiple training cage comprises at least one anterior-posterior balance training cage and at least one left-right balance training cage, is respectively equipped with treadmill in each training cage: be provided with swing governor motion in the below of anterior-posterior balance training cage and can drive described treadmill swing; Being provided with in the below of left-right balance training cage the governor motion that swings can drive described treadmill to swing; Described control station and each treadmill, swing governor motion, the governor motion that swings telecom-connect and control its kinestate.
Described each training cage comprises base and case respectively; The described anterior-posterior balance training base of cage is rotatably connected with the base plate of outer gimbal support, the base plate that described swing governor motion is arranged on outer gimbal support trains the base drive of cage to be connected with anterior-posterior balance can to drive base swing: described left-right balance trains the base of cage to be rotatably connected with the two end plates of outer gimbal support, described in swing on base plate that governor motion is arranged on outer gimbal support and train the base drive of cage to be connected with left-right balance base can be driven to swing; Case and the respective seat of described anterior-posterior balance training cage are fixedly linked, and the case of described left-right balance training cage is fixedly linked by support bar and outer gimbal support; Described treadmill is arranged on the base of each training cage respectively.
Described case encloses by transparent lucite and forms, and has smooth inner surface, and be provided with air-vent above case, case two ends are respectively equipped with removable top cover.
Described treadmill is by the crawler type treadmill of driven by motor.
The crawler belt of described crawler type treadmill have the fur of different coefficients of friction, canvas, gauze or bristle with sticking double faced adhesive tape.
The case of described anterior-posterior balance training cage is square case, and respective activity top cover is flat cover; The case of described left-right balance training cage is circular arc case, respective activity top cover is circular arc lid: the base both sides of described left-right balance training cage are connected to circular arc side plate, and two circular arc side plates are sleeved in described circular arc case and also can swing along circular arc case.
The afterbody of each training cage is respectively equipped with electricity irritation mechanism, this electricity irritation mechanism comprises rear plate and multiple electricity irritation bar, rear plate is arranged on the tail end of training cage, multiple electricity irritation bar equidistant arrangement is inclined and mounted on rear plate, electricity irritation bar is horizontal U-shaped structure, and each electricity irritation mechanism is electrically connected with control station respectively and controls it by control station and use electricity condition.
Also comprise night soil-treatment mechanism, this night soil-treatment mechanism comprises drawing and pulling type feces box, hang tilting feces baffle plate and push-down feces scraper plate, drawing and pulling type feces box is horizontally installed on the below of all training cage one end through outer gimbal support and can extracts out from outer gimbal support, hang tilting feces baffle plate be arranged on the treadmill outlet below of each training cage respectively and be inclined to set, the crawler belt of its upper end and treadmill is close, lower end is connected with drawing and pulling type feces box, push-down feces scraper plate is adnexa, for regularly manual, a small amount of feces dropped on base is scraped in drawing and pulling type feces box.
Bottom described outer gimbal support, corner is separately installed with universal wheel, the equal belt lock catch fixed mechanism of each universal wheel.
Described anterior-posterior balance training cage and left-right balance training cage are respectively two, and two left-right balance training cages are arranged on the side of outer gimbal support, and two anterior-posterior balance training cages are arranged on the opposite side of outer gimbal support.
The present invention has the following advantages and feature:
(1) device comprises two training cages to different training function, can mutually compare;
(2) each runway speed independently controls, and rat self-movement in each passage, can not be interfered, and limiting factor is each other less;
(3) material of the different coefficients of friction such as Pasting fur, canvas, emery cloth or bristle on crawler belt, improve rat sense of touch and static sense, different sensory function experiment demands can be met after choice for use, meet the clinical status that post-stroke carries out early exercise;
(4) owing to being provided with swing governor motion and the governor motion that swings, by reasonable set and control all around swing amplitude and speed, balance plate training clinically can be simulated more accurately, ensure that effectiveness and the safety of training simultaneously to greatest extent.
(5) train the electricity irritation mechanism of cage end to prevent rat tail and head by card, and effectively prevent urine from causing electricity irritation short-circuit failure phenomenon.
(6) the suspension tilting feces baffle plate of in real time process and the push-down feces scraper plate of regularly process all make feces drop in drawing and pulling type feces box to focus on.
(7) treadmill have employed computer control system completely, can control the balance of runway and various parameter of moving exactly, Real-time Obtaining experimental data, improves the analysis efficiency of experimental data, meets the development trend of animal physiological function quantitative analysis.
Accompanying drawing explanation
Fig. 1 is the population structure schematic diagram of brain injury in rats of the present invention sensation-balance-motion integrated training devices;
Fig. 2 is the population structure schematic diagram of the anterior-posterior balance training cage in the present invention;
Fig. 3 is the driving mechanism schematic diagram of the anterior-posterior balance training cage in the present invention;
Fig. 4 is the population structure schematic diagram of the left-right balance training cage in the present invention;
Fig. 5 is the driving mechanism schematic diagram of the left-right balance training cage in the present invention;
Fig. 6 is the left-right balance training cage cage body internal structure schematic diagram in the present invention;
Fig. 7 is the structural representation of the electricity irritation mechanism in the present invention.
Detailed description of the invention
See Fig. 1, coordinate see Fig. 2, Fig. 4, brain injury in rats sensation-balance-motion integrated training devices of the present invention, comprise outer gimbal support 1, control station 2 and multiple training cage, control station 2 is connected to the outside of outer gimbal support 1, and multiple training cage is arranged in outer gimbal support side by side, multiple training cage comprises at least one anterior-posterior balance training cage 4 and at least one left-right balance training cage 5, is respectively equipped with treadmill 41,51 in each training cage; Be provided with swing governor motion 6 in the below of anterior-posterior balance training cage 4 and can drive treadmill 41 swing; Being provided with in the below of left-right balance training cage 5 governor motion 7 that swings can drive treadmill 51 to swing; Control station 2 and each treadmill 41,51, swing governor motion 6, the governor motion 7 that swings telecom-connect and control its kinestate.
Control station 2 can do corresponding operation as requested on panel, to reach desired result.First row knob is for controlling the rotating speed of each treadmill, and the parameters such as the rotating speed of each treadmill of centralized numerical display, accumulated running time, distance travelled number; Second row knob is for controlling electricity irritation voltage, and the parameters such as centralized numerical display electricity irritation voltage, number of shocks; 3rd row's knob is used for control and swings speed, swing speed; The speed and centralized numerical display swings, the parameters such as swing speed; By more than USB port unloading all training parameters.
Each training cage comprises base and case respectively.The anterior-posterior balance training base 42 of cage 4 is rotatably connected with the base plate 11 of outer gimbal support 1, and the base plate 11 that swing governor motion 6 is arranged on outer gimbal support trains base 42 transmission of cage to be connected with anterior-posterior balance can to drive base swing; The base 52 of left-right balance training cage 5 is rotatably connected with the two end plates of outer gimbal support 1, and the base plate 11 that the governor motion 7 that swings is arranged on outer gimbal support 1 trains base 52 transmission of cage to be connected with left-right balance base can be driven to swing; The case 43 of anterior-posterior balance training cage is fixedly linked with respective seat, and the case 53 of left-right balance training cage 5 is fixedly linked by support bar 532 and outer gimbal support; Each treadmill is arranged on the base of each training cage respectively.
Each case encloses by transparent lucite and forms, and has smooth inner surface, is provided with air-vent 431,531 above case, and case two ends are respectively equipped with removable top cover 44,54.
Treadmill in the present invention is by the crawler type treadmill of driven by motor, and the crawler belt of crawler type treadmill has the fur of different coefficients of friction, canvas, gauze or bristle with sticking double faced adhesive tape.
The case of anterior-posterior balance training cage 4 is square case, and respective activity top cover is flat cover; The case of left-right balance training cage 5 is circular arc case, and respective activity top cover is circular arc lid; Base 52 both sides of left-right balance training cage 5 are connected to circular arc side plate 521 (see Fig. 6), and two circular arc side plates 521 are sleeved in circular arc case 53 and also can swing along circular arc case.
Coordinate see Fig. 7, the afterbody of each training cage is respectively equipped with electricity irritation mechanism 8, this electricity irritation mechanism comprises rear plate 81 and multiple electricity irritation bar 82, rear plate is arranged on the tail end of training cage, multiple electricity irritation bar equidistant arrangement is inclined and mounted on rear plate, electricity irritation bar 82 is in horizontal U-shaped structure, and each electricity irritation mechanism is electrically connected with control station 1 respectively and controls it by control station and use electricity condition.
The present invention also comprises night soil-treatment mechanism 9, this night soil-treatment mechanism 9 comprises drawing and pulling type feces box 91, hang tilting feces baffle plate 92 and push-down feces scraper plate 93, drawing and pulling type feces box 91 is horizontally installed on the below of all training cage one end through outer gimbal support 1 and can extracts out from outer gimbal support, hang tilting feces baffle plate 92 be arranged on the treadmill outlet below of each training cage respectively and be inclined to set, the crawler belt of its upper end and treadmill is close, lower end is connected with drawing and pulling type feces box, push-down feces scraper plate 93 is adnexa, for regularly manual, a small amount of feces dropped on base is scraped in drawing and pulling type feces box.
Bottom outer gimbal support 1 in the present invention, corner is separately installed with universal wheel (out not shown), the equal belt lock catch fixed mechanism of each universal wheel.
The concrete structure of the anterior-posterior balance training cage in the present invention as shown in Figures 2 and 3, its case 43 is fixedly linked with base 42, base 42 is rotatably connected with the base plate 11 of outer gimbal support 1, treadmill 41 is arranged on base 42, treadmill 41 is by crawler speed-regulating mechanism controls, and this crawler speed-regulating mechanism drives large belt wheel 412 by buncher 411, drives to small pulley 414 by Timing Belt 413, small pulley 414 is connected with the axis of crawler belt rod, realizes crawler speed-regulating.Have round air-vent 431 above square case 43, removable top cover 44 is established at two ends, top cover has bar shaped air-vent 431, and keep rat can not escape at the volley has again enough air simultaneously.Be provided with swing governor motion 6 in the below of anterior-posterior balance training cage 4, the base plate 11 that swing governor motion 6 is arranged on outer gimbal support trains base 42 transmission of cage to be connected with anterior-posterior balance can to drive base swing.The implementation method of this swing governor motion 6 is: motor 61 driving pulley 62, by Timing Belt 63 transmission, Timing Belt 63 drives power transmission shaft 65 to rotate, and power transmission shaft 65 drives double eccentric wheel 64 to rotate, and drives being synchronized with the movement of double link 67 by double-eccentric shaft 66; Double link 67 is connected with double-locking mechanism 68 transmission, and tow-locking structure 68 is welded on base 42, is connected below base 42 by central shaft 69 and outer gimbal support base plate 11 circular arc, makes base 42 with central shaft 69 for center of rotation swing.The swing feature of anterior-posterior balance training cage is: adopt double eccentric wheel+double-arm linkage to be synchronized with the movement, and overcome arm of force when anterior-posterior balance swings long, the difficult point that moment is larger, makes treadmill swing very steady.Electricity irritation mechanism 8 is positioned at the end of treadmill.Hang tilting feces baffle plate 92 and in real time the feces on crawler belt 415 is fallen into drawing and pulling type feces box, the feces dropped on base 42 regularly pushes in drawing and pulling type feces box 91 by adnexa push-down feces scraper plate 93.
The concrete structure of the left-right balance training cage 5 in the present invention is as shown in Fig. 4, Fig. 5, Fig. 6, its case 53 is fixedly linked by support bar 532 and outer gimbal support, its base 52 is rotatably connected with the two end plates of outer gimbal support 1, base 52 both sides are connected to circular arc side plate 521, two circular arc side plates 521 and are sleeved in circular arc case 53 and can swing along circular arc case.The base plate 11 that the governor motion 7 that swings is arranged on outer gimbal support 1 trains base 52 transmission of cage to be connected with left-right balance base can be driven to swing.Treadmill 51 is arranged on base 52, treadmill 51 is by crawler speed-regulating mechanism controls, and this crawler speed-regulating mechanism drives large belt wheel 512 by buncher 511, drives to small pulley 514 by Timing Belt 513, small pulley 514 is connected with the axis of crawler belt rod, realizes crawler belt 515 speed governing.Because the circular arc case 53 of left-right balance training cage 5 is fixed together by the base plate 11 of support bar 532 with outer gimbal support 1, when treadmill moves, circular arc case 53 is motionless.Venthole 531 is had above circular arc case 53, two ends are equipped with the circular arc removable top cover 54 of with handles 541, catch handle 541 can mention removable top cover 54, the operation of handled easily personnel, front and back cover also has venthole, and keep rat can not escape at the volley has again enough air simultaneously.The implementation method of governor motion 7 of swinging is: be with dynamic bearing to rotate by the motor 71 be arranged on above outer gimbal support base plate 11 by synchronizing wheel drive mechanism 72, two bearings 73 and an axle 74 is utilized to be fixed eccentric 75 position, drive eccentric 75 drive link 76 of side, connecting rod 76 with fall bar 77 be flexibly connected, drive bar 77 to move, the bar 77 that falls is direct and base 52 is fixing, makes treadmill realize swinging.The swing feature of left-right balance training cage is: use single eccentric+single double connecting rod, realizes multiple degrees of freedom and changes the direction of motion, drives treadmill to realize swinging.Electricity irritation mechanism 8 is positioned at treadmill end, hangs tilting feces baffle plate 92 and in real time the feces on crawler belt 12 is fallen into drawing and pulling type feces box.Push-down feces scraper plate 93 regularly manually clears up the feces dropped down onto on base 52.
A most preferred embodiment of the present invention is, anterior-posterior balance training cage 4 and left-right balance training cage 5 are respectively two, and two left-right balance training cages 5 are arranged on the side of outer gimbal support, and two anterior-posterior balance training cages 4 are arranged on the opposite side of outer gimbal support.
The present invention can realize the running training to rat, or the combined training that electricity irritation is combined with running training.Three in training cage, by the difference of the difference of jog mode, the difference of runway crawler belt material or angle experimental rat trained and compare.In bascule, make rat while running training, also will be subject to the impact of rocking both sides, the balanced capacity of observable rat by rocking treadmill.
The present invention is a kind of novel multi-functional rat device for healing and training meeting modern rehabilitation medicine theory, for the training, balance function training, sensory function training etc. of rat or other animals, not only can quantize training burden accurately, and can multifunction be realized.Both can carry out the research of single recovery training method, and the rehabilitation training pattern feeling balance one motion clinically can have been simulated again really, reach the object for the treatment of.
Claims (10)
1. a brain injury in rats sensation-balance-motion integrated training devices, it is characterized in that: comprise outer gimbal support, control station and multiple training cage, control station is connected to the outside of outer gimbal support, multiple training cage is arranged in outer gimbal support side by side, multiple training cage comprises at least one anterior-posterior balance training cage and at least one left-right balance training cage, is respectively equipped with treadmill in each training cage; Be provided with swing governor motion in the below of anterior-posterior balance training cage and can drive described treadmill swing; Being provided with in the below of left-right balance training cage the governor motion that swings can drive described treadmill to swing; Described control station and each treadmill, swing governor motion, the governor motion that swings telecom-connect and control its kinestate.
2. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, is characterized in that: described each training cage comprises base and case respectively; The described anterior-posterior balance training base of cage is rotatably connected with the base plate of outer gimbal support, and the base plate that described swing governor motion is arranged on outer gimbal support trains the base drive of cage to be connected with anterior-posterior balance can to drive base swing; The described left-right balance training base of cage is rotatably connected with the two end plates of outer gimbal support, described in swing on base plate that governor motion is arranged on outer gimbal support and train the base drive of cage to be connected with left-right balance base can be driven to swing; Case and the respective seat of described anterior-posterior balance training cage are fixedly linked, and the case of described left-right balance training cage is fixedly linked by support bar and outer gimbal support; Described treadmill is arranged on the base of each training cage respectively.
3. brain injury in rats sensation-balance-motion integrated training devices according to claim 2, it is characterized in that: described case encloses by transparent lucite and forms, and have smooth inner surface, be provided with air-vent above case, case two ends are respectively equipped with removable top cover.
4. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, is characterized in that: described treadmill is by the crawler type treadmill of driven by motor.
5. brain injury in rats sensation-balance-motion integrated training devices according to claim 4, is characterized in that: the crawler belt of described crawler type treadmill has the fur of different coefficients of friction, canvas, gauze or bristle with sticking double faced adhesive tape.
6. the brain injury in rats sensation-balance-motion integrated training devices according to Claims 2 or 3, it is characterized in that: the case of described anterior-posterior balance training cage is square case, respective activity top cover is flat cover: the case of described left-right balance training cage is circular arc case, and respective activity top cover is circular arc lid; The base both sides of described left-right balance training cage are connected to circular arc side plate, and two circular arc side plates are sleeved in described circular arc case and also can swing along circular arc case.
7. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, it is characterized in that: the afterbody of each training cage is respectively equipped with electricity irritation mechanism, this electricity irritation mechanism comprises rear plate and multiple electricity irritation bar, rear plate is arranged on the tail end of training cage, multiple electricity irritation bar equidistant arrangement is inclined and mounted on rear plate, electricity irritation bar is horizontal U-shaped structure, and each electricity irritation mechanism is electrically connected with control station respectively and controls it by control station and use electricity condition.
8. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, it is characterized in that: also comprise night soil-treatment mechanism, this night soil-treatment mechanism comprises drawing and pulling type feces box, hang tilting feces baffle plate and push-down feces scraper plate, drawing and pulling type feces box is horizontally installed on the below of all training cage one end through outer gimbal support and can extracts out from outer gimbal support, hang tilting feces baffle plate be arranged on the treadmill outlet below of each training cage respectively and be inclined to set, the crawler belt of its upper end and treadmill is close, lower end is connected with drawing and pulling type feces box, push-down feces scraper plate is adnexa, for regularly manual, a small amount of feces dropped on base is scraped in drawing and pulling type feces box.
9. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, is characterized in that: bottom described outer gimbal support, corner is separately installed with universal wheel, the equal belt lock catch fixed mechanism of each universal wheel.
10. brain injury in rats sensation-balance-motion integrated training devices according to claim 1, it is characterized in that: described anterior-posterior balance training cage and left-right balance training cage are respectively two, two left-right balance training cages are arranged on the side of outer gimbal support, and two anterior-posterior balance training cages are arranged on the opposite side of outer gimbal support.
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Cited By (1)
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CN112957690A (en) * | 2021-02-03 | 2021-06-15 | 台州职业技术学院 | Multifunctional rehabilitation training device for rats with brain injury |
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CN201315789Y (en) * | 2008-10-20 | 2009-09-30 | 淮北正华生物仪器设备有限公司 | Multi-track animal testing running platform |
CN102440197A (en) * | 2010-10-14 | 2012-05-09 | 上海理工大学 | Stupid-rat-maze-type intelligence rehabilitation training device |
CN203279635U (en) * | 2013-05-03 | 2013-11-13 | 同济大学 | Self-induction multi-track animal experiment treadmill |
CN203507056U (en) * | 2013-09-11 | 2014-04-02 | 上海理工大学 | Device for feeling-balance-motion integration training of brain injury rats |
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US5054427A (en) * | 1989-09-21 | 1991-10-08 | Hoover Judith L | Insertable stacking pet toy maze |
US7536977B1 (en) * | 2006-09-26 | 2009-05-26 | Williams Earl M | Animal exercising apparatus |
CN201315789Y (en) * | 2008-10-20 | 2009-09-30 | 淮北正华生物仪器设备有限公司 | Multi-track animal testing running platform |
CN102440197A (en) * | 2010-10-14 | 2012-05-09 | 上海理工大学 | Stupid-rat-maze-type intelligence rehabilitation training device |
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