CN105326664A - 含选择的聚二甲基硅氧烷表面活性剂的发泡性醇组合物 - Google Patents

含选择的聚二甲基硅氧烷表面活性剂的发泡性醇组合物 Download PDF

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CN105326664A
CN105326664A CN201510760810.1A CN201510760810A CN105326664A CN 105326664 A CN105326664 A CN 105326664A CN 201510760810 A CN201510760810 A CN 201510760810A CN 105326664 A CN105326664 A CN 105326664A
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J·R·维格纳
C·A·利塔奥
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Ecolab Inc
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Abstract

公开了含选择的聚二甲基硅氧烷表面活性剂的发泡性醇组合物。该聚二甲基硅氧烷表面活性剂是PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂，尤其是PEG-10直链聚二甲基硅氧烷表面活性剂。该组合物可用作抗微生物产品，尤其是护手或护肤产品。

Description

含选择的聚二甲基硅氧烷表面活性剂的发泡性醇组合物
本申请是申请号为200980122060.8申请的分案申请。
技术领域
本发明公开了含选择的聚二甲基硅氧烷(dimethicone)表面活性剂的发泡性醇组合物。该聚二甲基硅氧烷表面活性剂是PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂，尤其是PEG-10直链聚二甲基硅氧烷表面活性剂。该组合物可用作抗微生物产品，尤其是护手或护肤产品。
背景技术
醇组合物是合乎需要的护手和护肤品。它们针对宽范围的微生物例如革兰氏阳性和革兰氏阴性细菌和真菌是有效的。并且它们能够比其它抗微生物产品更快地杀死微生物。醇抗微生物产品可作为水稀液、凝胶、乳液和气溶胶泡沫获得。可商购的气溶胶醇泡沫，例如可从EcolabInc.(St.Paul,Minnesota)商购的QUIKCARETM依靠推进剂产生泡沫。因为醇的表面张力对于大多数表面活性剂而言太低而不能产生泡沫和在大气压下维持泡沫，所以需要推进剂。但是，气溶胶产品不太合乎需要，原因在于它们固有的不能视觉上监测容器中的产品含量、附加的包装复杂性和成本的缺点。从气溶胶罐和气溶胶推进剂转到允许用户看到容器中的产品含量同时维持发泡产品的美学益处的不太复杂的包装和化学是合乎需要的。在这个背景下，作出了本发明。
发明内容
发明概要
已经令人惊奇地发现，PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂，尤其是PEG-10直链聚二甲基硅氧烷表面活性剂在透明或半透明、非气溶胶包装中在大气压下在醇产品中产生泡沫是特别有效的。PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂与具有相同PEG链长度、但是具有不同聚合物体系构造(polymerarchitecture)的聚二甲基硅氧烷表面活性剂相比更有效。
在一些实施方案中，本发明涉及含PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂、醇和水的非气溶胶抗微生物组合物，其中所述聚二甲基硅氧烷能够产生大于20mm的平均泡沫高度而无需多于5％的额外表面活性剂。在一些实施方案中，本发明涉及含PEG-10直链聚二甲基硅氧烷表面活性剂、醇和水的非气溶胶抗微生物组合物，其中所述聚二甲基硅氧烷能够产生大于20mm的平均泡沫高度而无需多于5％的额外表面活性剂。在一些实施方案中，该组合物还含有额外的材料例如皮肤调理剂、萜类化合物、螯合剂和防腐剂。
这些及其它实施方案对阅读了以下一些实施方案的详细描述之后的本领域和其它领域的技术人员来说将是显而易见的。然而，应当理解，这种概要和详细描述仅举例说明了各种实施方案的一些实施例，并且不用来限制所要求的本发明。
一些实施方案的详细描述
如上所讨论，本发明总体上涉及包括PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂，尤其是PEG-10直链聚二甲基硅氧烷表面活性剂的发泡性醇组合物。该组合物可用作抗微生物产品，尤其是护手或护肤产品。
PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂
已经令人惊奇地发现，PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂，尤其是PEG-10直链聚二甲基硅氧烷表面活性剂比具有相同PEG链长度、但是具有不同聚合物体系构造的聚二甲基硅氧烷表面活性剂在产生和稳定化醇组合物中的泡沫方面更有效。
更具体地说，已经发现，PEG与聚二甲基硅氧烷的直链嵌段共聚物(具体来说，具有INCI名称PEG-8聚二甲基硅氧烷、PEG-10聚二甲基硅氧烷和PEG-12聚二甲基硅氧烷)能够产生足够的泡沫高度以用作非气溶胶发泡性醇组合物的主发泡组分，而具有相同INCI名称、但是具有不同聚合物体系构造的共聚物不是这样。例如，具有侧挂PEG基团或其它高度支化聚合物结构的聚合物不会产生足以用作主发泡表面活性剂的泡沫。在PEG聚二甲基硅氧烷共聚物的情况下，直链嵌段共聚物是指聚乙二醇链单元与直链聚二甲基硅氧烷主链的末端连接的时候：
其中R＝CH3或CH2CH3，m＝平均4-20，y＝1-5，和n＝平均8-12。
侧挂共聚物是指具有沿着聚二甲基硅氧烷主链连接的并且可以与或可以不与聚二甲基硅氧烷的末端链端连接的PEG基团的直链聚二甲基硅氧烷聚合物。此类侧挂共聚物通常认为具有梳状或类似梳状的结构，例如：
其中R独立地＝CH3、CH2CH3或直接地与硅氧烷端基连接的乙氧基化烷基链(例如CH2CH2CH2O(CH2CH2O)nH)，a＝重复性硅氧烷基团。
可商购的PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂的一些实例包括得自MomentivePerformanceMaterials的Silsoft810(PEG-8)和Silsoft870(PEG-12)，和得自Siltech的SilsurfDI-1010(PEG-10)。在一些实施方案中，聚二甲基硅氧烷表面活性剂优选是PEG-10直链聚二甲基硅氧烷表面活性剂。
所述聚二甲基硅氧烷表面活性剂可以按大约0.5-大约10wt％，大约1.0-大约7wt％和大约2-大约5wt％存在于所述醇组合物中。
醇
除了水之外，所述组合物包括醇。醇优选是低级链醇例如C2-C4醇。适合的醇的实例包括乙醇，丙醇，例如异丙醇和正丙醇，和丁醇。醇优选是乙醇。
所述组合物可以含有一种醇，或两种或更多种醇的混合物。醇优选按大约50-大约90wt％，大约54-大约85wt％和大约60-大约80wt％的活性醇的量存在于所述组合物中。
皮肤调理剂
所述组合物可以非必要地包括至少一种皮肤调理剂，例如润肤剂、保湿剂、吸留剂或提供增湿、皮肤软化、皮肤屏障维持、抗刺激或其它皮肤健康益处的其它增湿剂。润肤剂的某些非限制性实例包括苯甲酸烷基酯，肉豆蔻酸肉豆蔻基酯，肉豆蔻酸鲸蜡酯，二油酸甘油酯，月桂酸甲酯，月桂酸PPG-9酯，lauryllacylateallantoin，棕榈酸辛酯，羊毛脂，丙二醇，丁二醇，乙二醇单丁醚，甘油，脂肪酸，天然油，例如杏仁油、矿物油、低芥酸菜子油、芝麻油、大豆油、麦芽油、玉米油、花生油和橄榄油，肉豆蔻酸异丙酯，肉豆蔻醇，芦荟，水解丝蛋白，维生素E，硬脂醇，棕榈酸异丙酯，山梨糖醇，氨基酸络合物，水解植物蛋白和聚乙二醇。保湿剂的某些非限制性实例包括羟乙基脲、琼脂糖、脲、钠PCA、精氨酸PCA、果糖、葡萄糖、谷氨酸、甘油、蜂蜜、乳糖、麦芽糖、聚乙二醇、山梨糖醇和它们的混合物。吸留剂的某些非限制性实例包括矿脂、牛油树脂、鳄梨油、香薄荷油(balmmintoil)、鱼肝油、矿物油、三肉豆蔻酸甘油酯、硬脂酸硬脂基酯、合成蜡或它们的混合物。其它增湿剂的某些非限制性实例包括乙基己基甘油，胆固醇，胱氨酸，透明质酸，角蛋白，卵磷脂，卵黄，甘氨酸，PPG-12，聚季铵盐聚合物例如聚季铵盐-11(polyquaternium-11)，benentrimoniumchloride，二羟基丙基PEG-5氯化亚油铵，油酸甘油酯，PEG-7甘油基椰油酸酯，椰油糖苷，PEG-200氢化甘油基棕榈酸酯，泛醇，视黄醇、水杨酸、植物油，甲基葡糖聚氧乙烯醚-10，甲基葡糖聚氧乙烯醚-20，皮肤调理剂例如甘油聚氧乙烯醚-26的乙氧基化衍生物和乙氧基化牛油树脂，和它们的混合物。最后，抗刺激剂的某些非限制性实例包括没药醇和泛醇。
本领域技术人员将识别不同皮肤调理剂的不同强度并相应地配制。在一些实施方案中，皮肤调理剂优选按大约0.01-大约20wt％，大约0.05-大约15wt％和大约0.1-大约10wt％的量存在于所述组合物中。
萜类化合物
所述组合物可以非必要地包括萜类化合物。萜类化合物定义为具有这样的分子结构的材料，即该分子结构含有由异戊二烯(2-甲基丁-1,3-二烯)单元组成的碳主链。异戊二烯含有五个碳原子，并因此任何萜类化合物中的碳原子的数目是五的倍数。据信，萜类化合物帮助促进抗微生物化合物和防腐剂被细菌和真菌的细胞的摄取，从而提高抗微生物化合物或防腐剂的功效。参见美国专利号6,319,958和DE19523320，它们以其全文引入作为参考。萜类化合物的某些非限制性实例包括α-萜品烯、桉叶素、柠檬醛、香茅醛、香茅醇、金合欢醇、香叶醇、柠檬烯、沉香醇、薄荷酮、橙花叔醇、萜品醇、莰烯、薄荷酮、月桂烯、橙花醇、tetrayhydrogeraniol、四氢芳樟醇、apritone和没药醇。萜类化合物优选是金合欢醇、橙花叔醇、没药醇或apritone。
所述萜类化合物优选按大约0.005-大约5wt％，大约0.05-大约2.5wt％和大约0.1-大约1.5wt％的量存在于所述组合物中。
螯合剂
所述组合物可以非必要地包括螯合剂。螯合剂的实例包括膦酸和膦酸酯、磷酸酯、氨基羧酸酯和它们的衍生物、焦磷酸酯、亚乙基二胺和亚乙基三胺衍生物、醇酸和单、二和三羧酸盐和它们相应的酸。其它螯合剂包括nitroloacetates和它们的衍生物，和它们的混合物。氨基羧酸酯的实例包括氨基乙酸酯和其盐。适合的氨基乙酸酯包括：N-羟基乙基氨基二乙酸；羟基亚乙基二胺四乙酸，次氨基三乙酸(NTA)；亚乙基二胺四乙酸(EDTA)；N-羟乙基-亚乙基二胺三乙酸(HEDTA)；亚乙基二胺四乙酸四钠(EDTA)；二亚乙基三胺五乙酸(DTPA)；和丙氨酸-N,N-二乙酸等；n-羟基乙基亚氨基二乙酸；它们的碱金属盐及它们的混合物。适合的氨基磷酸酯包括氮川三亚甲基磷酸酯及其它具有含少于8个碳原子的烷基或碱性基团的氨基磷酸酯。示例性的聚羧酸酯亚氨基二琥珀酸(IDS)、聚丙烯酸钠、柠檬酸、葡萄糖酸、草酸、其盐、其混合物等。附加的聚羧酸酯包括柠檬酸或柠檬酸酯型螯合剂、聚合物聚羧酸酯和丙烯酸或聚丙烯酸型螯合剂。其它螯合剂包括聚天冬氨酸或天冬氨酸与其它氨基酸的共缩合物、C4-C25-单或-二羧酸和C4-C25-单或-二胺。示例性的聚合物聚羧酸酯包括聚丙烯酸、马来酸类/烯烃共聚物、丙烯酸类/马来酸类共聚物、聚甲基丙烯酸、丙烯酸-甲基丙烯酸共聚物、水解聚丙烯酰胺、水解聚甲基丙烯酰胺、水解聚酰胺-甲基丙烯酰胺共聚物、水解聚丙烯腈、水解聚甲基丙烯腈、水解丙烯腈-甲基丙烯腈共聚物等。
所述螯合剂可以按大约0.01-大约5wt％，大约0.05-大约3wt％和大约0.1-大约1.5wt％的量存在于所述组合物中。
防腐剂
所述组合物可以非必要地包括防腐剂。一般而言，防腐剂符合特定的类别，包括酚类化合物、卤素化合物、季铵化合物、金属衍生物、胺、烷醇胺、硝基衍生物、双胍、analides、有机硫和硫-氮化合物、对羟基苯甲酸烷基酯和其它化合物。酚类化合物抗微生物剂的某些非限制性实例包括五氯苯酚、邻苯基苯酚、氯二甲苯酚、对氯间甲酚、对氯苯酚、氯代百里酚、间甲酚、邻甲酚、对甲酚、异丙基甲酚、混合甲酚、苯氧基乙醇、苯氧基乙基对羟基苯甲酸酯、苯氧基异丙醇、对羟基苯甲酸苯酯、间苯二酚和它们的衍生物。卤素化合物的某些非限制性实例包括三氯羟基二苯醚(三氯生)、三氯异氰脲酸钠、二氯异氰酸钠、碘－聚(乙烯基吡咯烷酮)络合物和溴化合物，例如2-溴-2-硝基丙烷-1,3-二醇，和它们的衍生物。季铵化合物的某些非限制性实例包括氯化苄烷铵、氯化苄乙胺、氯化山嵛基三甲基铵、氯化十六烷基三甲铵和它们的衍生物。胺和含硝基化合物的某些非限制性实例包括六氢-1,3,5-三(2-羟乙基)-s-三嗪、二硫代氨基甲酸盐例如二甲基二硫代氨基甲酸钠和它们的衍生物。双胍的某些非限制性实例包括聚氨基丙基双胍和葡萄糖酸氯己定。对羟基苯甲酸烷基酯的某些非限制性实例包括对羟基苯甲酸甲基、乙基、丙基和丁基酯。
所述防腐剂优选按大约0-大约3wt％，大约0.1-大约2wt％和大约0.2-大约1wt％的量存在于所述组合物中。
增稠剂
所述组合物可以非必要地包括增稠剂。示例性的增稠剂包括(1)纤维素增稠剂和它们的衍生物，(2)天然胶质(gum)，(3)淀粉，(4)硬脂酸酯和(5)脂肪酸醇。纤维素增稠剂的某些非限制性实例包括羧甲基羟乙基纤维素、纤维素、羟丁基甲基纤维素、羟乙基纤维素、羟丙基纤维素、羟丙基甲基纤维素、甲基纤维素、微晶纤维素、纤维素硫酸钠等。天然胶质的某些非限制性实例包括阿拉伯胶、角叉菜胶钙、瓜尔胶、明胶、瓜尔胶、羟丙基瓜尔胶、刺梧桐树胶、巨藻、刺槐豆胶、果胶、角叉菜胶钠、黄蓍胶、黄原胶等。淀粉的某些非限制性实例包括燕麦粉、马铃薯淀粉、小麦粉、小麦淀粉等。硬脂酸酯的某些非限制性实例包括PEG-150二硬脂酸酯、甲氧基PEG-22/十二烷基二醇共聚物等。脂肪酸醇的某些非限制性实例包括辛醇、十六/十八醇、月桂醇、油醇、棕榈仁醇等。
所述组合物中的增稠剂的量取决于组合物的所需粘度。所述组合物优选具有足够低以经由发泡器例如气喷发泡器泵送和允许发泡的粘度。
额外功能性成分
额外功能性成分可用来改进组合物的有效性。此类额外功能性成分的某些非限制性实例包括皮肤感觉改进剂、抗氧化剂、香料、染料和它们的混合物。
皮肤感觉改进剂
所述组合物可以非必要地包括皮肤感觉改进剂用于提高组合物在用户的皮肤或手上的"感觉"。例如，当施涂于用户的皮肤时或在组合物的多重施用之后，组合物具有鳞片状或砂粒质质地可能是不合需要的。皮肤感觉改进剂的某些非限制性实例包括硅氧烷共聚物例如氨基封端的聚二甲基硅氧烷，环状聚二甲基硅氧烷，双-PEG/PPG-20/20聚二甲基硅氧烷和十八烷氧基三甲基硅烷，天然存在或合成的脂肪酸酯或醚，和聚亚烷基二醇。
如果包括皮肤感觉改进剂，则优选它按大约0.001-大约5wt％，大约0.01-大约3wt％和大约0.1-大约2wt％的量存在于所述组合物中。
抗氧化剂
所述组合物可以非必要地包括抗氧化剂以便经由自由基的除去改进皮肤状况，和改进产品稳定性。抗氧化剂的某些非限制性实例包括视黄醇和视黄醇衍生物、抗坏血酸和抗坏血酸衍生物、BHA、BHT、β胡萝卜素、半胱氨酸、异抗坏血酸、氢醌、生育酚和生育酚衍生物等。
如果包括抗氧化剂，则优选它按大约0.001-大约2wt％，大约0.01-大约1wt％和大约0.05-大约0.5wt％的量存在于所述组合物中。
香料
所述组合物可以非必要地包括香料。可能的香料的实例包括天然油或天然衍生的材料，和合成香料例如烃、醇、醛、酮、酯、内酯、醚、腈和多官能化物。天然油的非限制性实例包括以下：罗勒(Ocimumbasilicum)油、bay(Pimentoacris)oil、蜜蜂花(Monardadidyma)油、香柠檬(Citrusaurantiumbergamia)油、小豆蔻(Elettariacardamomum)油、杉木(Cedrusatlantica)油、甘菊(Anthemisnobilis)油、肉桂(Cinnamomumcassia)油、枫茅(Cymbopogonnardus)油、clary(Salviasclarea)油、丁香(Eugeniacaryophyllus)油、丁香叶(Eufeniacaryophyllus)油、油莎草油、cypress(Cupressussempervirens)油、柠檬桉油、geraniummaculatum油、姜(Zingiberofficinale)油、葡萄柚(Citrusgrandis)油、榛子(Corylusavellana)胡桃油、茉莉(Jasminumofficinale)油、Juniperuscommunis油、刺柏焦油、铅笔柏油、kiwi(Actinidiachinensis)水、lavandin(Lavandulahybrida)油、熏衣草(Lavandulaangustifolia)油、熏衣草(Lavandulaangustifolia)水、柠檬(Citrusmedicalimonum)油、柠檬香草(Cymbopogonschoenanthus)油、lime(Citrusaurantifolia)油、菩提树(Tiliacordata)油、菩提树(Tiliacordata)水、蜜柑(Citrusnobilis)油、肉豆蔻(Myristicafragrans)油、橙(Citrusaurantiumdulcis)花油、橙(Citrusaurantiumdulcis)油、橙(Citrusaurantiumdulcis)水、广藿香(Pogostemoncablin)油、薄荷(Menthepiperita)油、薄荷(Menthepeperita)水、迷迭香(Rosmarinusofficinalis)油、玫瑰油、玫瑰(Rosadamascena)提取物、玫瑰(Rosamultiflora)提取物、红木(Anibarosaeodora)提取物、红根草(Salviaofficinalis)油、檀香木(Santalumalbum)油、绿薄荷(Mentheviridis)油、茶树(Melaleucaalternifolia)油和衣兰树(Canangaodorata)油。合成烃香料的某些非限制性实例包括石竹烯、β-法呢烯、柠檬烯、α-蒎烯和β-蒎烯。合成醇香料的某些非限制性实例包括白檀醇、香茅醇、沉香醇、苯乙醇和α-萜品醇(R＝H)。合成醛香料的某些非限制性实例包括2-甲基十一醛、柠檬醛、己基肉桂醛、isocycolcitral、铃兰醛和10-十一烯醛。合成酮香料的某些非限制性实例包括cashmeran、α-紫罗酮、isocyclemoneE、koavone、麝香酮和tonalide。合成酯香料的某些非限制性实例包括乙酸苄酯、乙酸4-叔丁基环己酯(顺式和反式)、乙酸柏木酯、cyclacet、乙酸异冰片酯和乙酸α-萜品酯(R＝乙酰基)。合成内酯香料的某些非限制性实例包括香豆素、茉莉内酯、muskalactone和桃醛。合成醚香料的某些非限制性实例包括ambroxan、花药和galaxolide。合成腈香料的某些非限制性实例包括肉桂腈和gernonitrile。最后，合成多功能性香料的某些非限制性实例包括水杨酸戊酯、异丁子香酚、二氢茉莉酮酸甲酯、洋茉莉醛、lyral和香草醛。
所述组合物可以包括香料的混合物，包括天然和合成香料的混合物。香料可以按至多大约5wt％，优选大约0.01-大约3wt％，大约0.05-大约1wt％，大约0.1-大约0.2wt％的量存在于所述组合物中。
染料
所述组合物可以非必要地包括染料。染料的实例包括任何水溶性或产品可溶性染料，任何FD&C或D&C批准的染料。染料可以按至多大约0.5wt％，优选大约0.00001-大约0.1wt％，大约0.0001-大约0.01wt％，大约0.0001-大约0.0005wt％的量存在。
组合物
所述非气溶胶醇组合物特别可用作护手和护肤所述组合物用于减少目标表面上的微生物。
在一些实施方案中，所述组合物包括少于大约10％，少于大约5％或少于大约1％的任何额外表面活性剂。额外表面活性剂的使用可以受限制，因为选择的聚二甲基硅氧烷表面活性剂能够产生和维持泡沫，而无需额外表面活性剂的帮助。
在一些实施方案中，所述组合物除PEG-8、PEG-10或PEG-12直链聚二甲基硅氧烷表面活性剂之外还包括少于大约10％，少于大约5％或少于大约1％的任何额外硅氧烷材料。
在一些实施方案中，所述组合物包括少于大约10％，少于大约5％或少于大约1％的任何泡沫稳定剂。
在一些实施方案中，所述组合物可以不含或基本上不含额外表面活性剂、额外硅氧烷材料或泡沫稳定剂。在一些实施方案中，所述组合物可以不含或基本上不含含氟表面活性剂。
所述组合物可以作为水稀液、结构化液体或乳液提供。所述组合物优选作为即用型(readytouse)组合物提供，这是指所述组合物按可以在不需要首先稀释它的情况下施用的方式提供。
包装和分配器
所述组合物可以按各种包装尺寸提供。包装尺寸的实例包括1.5oz、500ml和1升瓶子。选择的包装优选具有泵压头发泡器。可商购的泵压头发泡器的实例包括得自RexamPLC(London,England,以前是Airspray)的F2发泡器，和得自RiekeCorporation(Auburn,Indiana)的RF-17Palm发泡器。
定义
对于下面限定的术语，应该应用这些定义，除非在权利要求或本说明书中的其它地方中给出了不同的定义。
所有数值在此认为由术语"大约"修饰，不论是否明确地指出。术语"大约"通常指本领域技术人员将认为与列举的值等效的数值范围(即，具有相同的作用或结果)。在许多情况下，术语"大约"可以包括四舍五入到最接近的有效数字的数值。
重量百分率，按重量计的百分率，％按重量计，wt％等是同义词，是指按物质的重量除以组合物的重量并乘以100计算出的物质浓度。
通过终点列举的数值范围包括该范围涵盖的所有数值(例如1到5包括1、1.5、2、2.75、3、3.80、4和5)。
当用于本说明书和所附权利要求书时，单数形式"a"、"an"、和"the"包括复数指示，除非内容明显指示相反。因此，例如，所谓的含"化合物"的组合物包括两种或更多种化合物的混合物。当用于本说明书和所附权利要求书时，术语"或"通常按其包括"和/或"的意义使用，除非上下文明显指示相反。
为了更完全理解本发明，给出以下实施例举例说明某些实施方案。这些实施例和实验应理解为是说明性而非限制性的。所有份数按重量计，除非当相反指示时。
实施例
实施例1-硅氧烷表面活性剂筛选
实施例1显示各种硅氧烷表面活性剂和它们产生稳定泡沫的能力。使用以下泡沫高度筛选程序评价硅氧烷表面活性剂的发泡能力。
原料溶液制备：制备由75.6％乙醇SDA40B(190proof，99.5％活性)和24.4％水组成的溶液。
样品制备：向20mL小瓶中称量大约0.35g硅氧烷表面活性剂和9.65g原料溶液。然后混合该溶液直到获得均匀溶液。
泡沫高度筛选：为了筛选每种溶液的泡沫高度，将该制备溶液的小部分(～1mL)投入具有气喷发泡泵压头的2oz瓶子，冲洗周围，并摈弃。在瓶子冲洗之后，然后将样品制剂的残留内容物转移到具有气喷发泡泵压头的2oz瓶子中。起动加注该发泡泵压头直到液体或泡沫经由该发泡器头产生。进行至多三次附加的泵送以确保已经经由该泵抽空初始溶液。在起动加注该泵之后，进行三次附加的泵送，将材料引导至20mL玻璃小瓶中。立即使用尺子测量液相线上方的泡沫的高度(毫米)。再重复该过程一次并将两个泡沫高度测量值平均。结果示于表1中。
表1-硅氧烷表面活性剂筛选
表1显示仅直链聚二甲基硅氧烷能够产生大于20mm的泡沫高度。表1中的具有大于20mm的泡沫高度的示例性聚二甲基硅氧烷表面活性剂包括得自Siltech的SilsurfDI-1010、得自GESilicone的Silsoft810和得自Momentive的Silsoft870。
实施例2-泡沫高度相比硅氧烷表面活性剂浓度
实施例2测定聚二甲基硅氧烷表面活性剂浓度对泡沫高度的影响。对于这一实施例，使用以下试验测量泡沫高度：
原料溶液制备：用以下配方制备溶液：
原料溶液 (g)
乙醇SDA 40B(190Proof,99.5％活性) 811.11
法呢醇(Farnesol) 2.78
没药醇 1.11
乙基己基甘油 3.33
水 181.67
将如下量添加到60mL罐中。所使用的硅氧烷表面活性剂是SilsurfDI-1010、Silsoft810和Silsoft870。
样品制备：向60mL罐中，
样品 1 2 3 4 5 6 7
原料溶液(g) 22.500 45.00 45.00 45.00 45.00 45.00 45.00
硅氧烷表面活性剂(g) 0.125 0.50 1.00 1.50 1.75 2.50 5.00
硅氧烷表面活性剂(wt％) 0.5 1 2 3 3.5 5 10
水(g) 2.375 4.50 4.00 3.50 1.25 2.50 0.00
泡沫高度筛选：为了筛选每种溶液的泡沫高度，使用该制备溶液的小部分(～1mL)冲洗具有气喷发泡泵压头的2oz瓶子并摈弃。在冲洗瓶子之后，然后将样品制剂的残留内容物转移到具有气喷发泡泵压头的2oz瓶子中。起动加注该发泡泵压头直到液体或泡沫经由该发泡器头产生。进行至多三次附加的泵送以确保已经经由该泵抽空冲洗液。在起动加注该泵之后，进行三次附加的泵送，将材料引导至20mL玻璃小瓶中。立即使用尺子测量液相线上方的泡沫的高度(毫米)。再重复该过程并将两个泡沫高度测量值平均。结果示于表2中。
表2-泡沫高度(mm)
样品 1 2 3 4 5 6 7
Silsoft 810 12 11.5 20 24 25.5 26 26
Silsurf DI-1010 14.5 22.5 23.5 24 25 26 26.5
Silsoft 870 13 17 23.5 25.5 26 26 27
表2显示为了产生20mm泡沫，优选0.5-1克硅氧烷表面活性剂(样品2和3)。
上述概要、详细描述和实施例提供理解本发明和本发明的一些具体实施例实施方案的重要基础。因为本发明可以包括各种实施方案，所以上述信息不是用来限制的。本发明归属于权利要求。

Claims (19)

1.非气溶胶发泡性抗微生物组合物，包含：
a)包括PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂的具有大于20mm的平均泡沫高度的发泡剂；
b)大约50-大约90wt％的C2-C4醇；和
c)水
其中存在少于大约5wt％的额外表面活性剂，
且其中所述组合物不含泡沫稳定剂。
2.权利要求1的抗微生物组合物，还包含大约0.01-大约20wt％的皮肤调理剂。
3.权利要求2的抗微生物组合物，其中所述皮肤调理剂选自乙基己基甘油、羟乙基脲、脲、泛醇、甘油、肉豆蔻酸异丙酯、丙二醇、生育酚乙酸酯、聚季铵盐-11和它们的混合物。
4.权利要求1的抗微生物组合物，还包含选自皮肤感觉改进剂、抗氧化剂、香料、染料和它们的混合物的额外成分。
5.权利要求1的抗微生物组合物，其中所述发泡剂是PEG-10直链聚二甲基硅氧烷表面活性剂。
6.权利要求1的抗微生物组合物，其中所述组合物不含额外表面活性剂。
7.发泡性抗微生物组合物，包含：
a)包含PEG-10直链硅氧烷表面活性剂的具有大于20mm的平均泡沫高度的发泡剂；
b)大约50-大约90wt％的C2-C4醇；和
c)水
其中存在少于大约5wt％的额外表面活性剂，
且其中所述组合物不含泡沫稳定剂。
8.权利要求7的抗微生物组合物，还包含大约0.005-大约5wt％的萜类化合物。
9.权利要求7的抗微生物组合物，还包含选自皮肤感觉改进剂、抗氧化剂、香料、染料和它们的混合物的额外成分。
10.权利要求7的抗微生物组合物，其中所述组合物基本上不含额外硅氧烷材料。
11.权利要求7的抗微生物组合物，还包含选自乙基己基甘油、羟乙基脲、脲、泛醇、甘油、肉豆蔻酸异丙酯、丙二醇、生育酚乙酸酯、聚季铵盐-11和它们的混合物的皮肤调理剂。
12.发泡性抗微生物组合物，包含：
a)包括PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂的具有大于20mm的平均泡沫高度的发泡剂；
b)大约60-大约80wt％的C2-C4醇；
c)大约0.1-大约10wt％的选自甘油、乙基己基甘油、羟乙基脲、脲、泛醇和它们的混合物的皮肤调理剂；和
d)水，
其中所述组合物不含泡沫稳定剂。
13.权利要求12的抗微生物组合物，还包含大约0.005-大约5wt％的萜类化合物。
14.权利要求12的抗微生物组合物，还包含选自皮肤感觉改进剂、抗氧化剂、香料、染料和它们的混合物的额外成分。
15.权利要求12的抗微生物组合物，其中所述组合物基本上不含额外硅氧烷材料。
16.权利要求12的抗微生物组合物，其中所述发泡剂是PEG-10直链聚二甲基硅氧烷。
17.发泡性抗微生物组合物，其基本上由以下组分组成：
a)包括PEG-8至PEG-12直链聚二甲基硅氧烷表面活性剂的具有大于20mm的平均泡沫高度的发泡剂；
b)大约54-大约85wt％的至少两种C2-C4醇；
c)大约0.01-大约20wt％的螯合剂；
d)大约0.01-大约20wt％的选自甘油、肉豆蔻酸异丙酯、丙二醇、生育酚乙酸酯、聚季铵盐-11和它们的混合物的皮肤调理剂；
f)大约0-大约3wt％的对羟基苯甲酸酯；和
g)水。
18.权利要求17的抗微生物组合物，还包含选自皮肤感觉改进剂、抗氧化剂、香料、染料和它们的混合物的额外成分。
19.权利要求17的抗微生物组合物，其中所述发泡剂是PEG-10直链聚二甲基硅氧烷表面活性剂。
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Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060113907A (ko) 2003-09-29 2006-11-03 에테나 헬스케어 인코포레이티드 높은 알코올 함량의 겔-유사 및 포옴 조성물
DE102004062775A1 (de) 2004-12-21 2006-06-29 Stockhausen Gmbh Alkoholischer Pumpschaum
AU2006222502B2 (en) 2005-03-07 2010-02-11 Deb Ip Limited High alcohol content foaming compositions with silicone-based surfactants
US20070148101A1 (en) * 2005-12-28 2007-06-28 Marcia Snyder Foamable alcoholic composition
US8119115B2 (en) 2006-02-09 2012-02-21 Gojo Industries, Inc. Antiviral method
US8450378B2 (en) * 2006-02-09 2013-05-28 Gojo Industries, Inc. Antiviral method
US9629361B2 (en) * 2006-02-09 2017-04-25 Gojo Industries, Inc. Composition and method for pre-surgical skin disinfection
US20070185216A1 (en) * 2006-02-09 2007-08-09 Marcia Snyder Antiviral method
US7842725B2 (en) 2008-07-24 2010-11-30 Ecolab USA, Inc. Foaming alcohol compositions with selected dimethicone surfactants
US9156215B2 (en) 2010-12-06 2015-10-13 Novartis Ag Method for making silicone hydrogel contact lenses
US9089129B2 (en) 2011-10-07 2015-07-28 American Sterilizer Company Non-aerosol foaming alcohol hand sanitizer
US8304375B1 (en) 2011-10-13 2012-11-06 Kimberly-Clark Worldwide, Inc. Foaming formulations including silicone polyesters
US8865195B2 (en) * 2011-10-13 2014-10-21 Kimberly-Clark Worldwide, Inc. Foaming formulations and cleansing products including silicone polyesters
KR101852487B1 (ko) 2011-11-28 2018-04-27 (주)아모레퍼시픽 방부력이 우수한 피부 외용제 조성물
AU2013222251B2 (en) * 2012-02-24 2016-07-28 Gojo Industries, Inc. Antimicrobial and foamable alcoholic compositions
US9439841B2 (en) 2013-06-06 2016-09-13 Ecolab Usa Inc. Alcohol based sanitizer with improved dermal compatibility and feel
DE102013213252A1 (de) * 2013-07-05 2015-01-08 Schülke & Mayr GmbH Verwendung eines Isopropanol enthaltenden Mittels zur Bekämpfung von Caliciviridae
JP2016534028A (ja) * 2013-10-23 2016-11-04 ゴジョ・インダストリーズ・インコーポレイテッド 分枝状の起泡性界面活性剤を含有する発泡性のアルコール組成物
JP6734781B2 (ja) 2014-03-14 2020-08-05 ゴジョ・インダストリーズ・インコーポレイテッド 手指衛生ガイドラインの順守を奨励するために改善された審美性及び皮膚コンディショニングを有する手指消毒剤
TW201538181A (zh) * 2014-03-19 2015-10-16 Pures Biotech Co Ltd 用於潤滑保濕消毒滅菌之半流體組成物及其使用方法
AU2015297024A1 (en) 2014-07-31 2017-03-02 Kimberly-Clark Worldwide, Inc. Anti-adherent alcohol-based composition
US9969885B2 (en) 2014-07-31 2018-05-15 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
US10238107B2 (en) 2014-07-31 2019-03-26 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
US10758387B2 (en) * 2014-10-16 2020-09-01 Cook Medical Technologies Llc Endovascular stent graft assembly and delivery device
WO2016085906A1 (en) 2014-11-25 2016-06-02 Gojo Industries, Inc. Foamable alcoholic sanitizing compositions with branched polyethoxylated dimethicone foaming surfactants and isopropanol
AU2015390078B2 (en) 2015-04-01 2020-11-26 Kimberly-Clark Worldwide, Inc. Fibrous substrate for capture of Gram negative bacteria
JP7114474B2 (ja) 2016-02-11 2022-08-08 ゴジョ・インダストリーズ・インコーポレイテッド 高品質の非エアロゾル手除菌用泡
DE102016003804A1 (de) * 2016-03-25 2017-09-28 Laverana Gmbh & Co. Kg Naturkosmetische Zubereitung zur Pflege der Haut des schlafenden Menschen
EP3436156A1 (en) 2016-03-31 2019-02-06 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
WO2017173241A1 (en) 2016-03-31 2017-10-05 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
CA3021325A1 (en) 2016-04-20 2017-10-26 S.C. Johnson & Son, Inc. Foaming antimicrobial compositions
GB2565511B (en) 2016-05-26 2022-04-13 Kimberly Clark Co Anti-adherent compositions and methods of inhibiting the adherence of microbes to a surface
US9511105B1 (en) * 2016-07-25 2016-12-06 Mohamed Jihath Mohammad Jamal Al Attar Piles treatment
AU2017365019A1 (en) 2016-11-23 2019-07-11 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US20180140545A1 (en) * 2016-11-23 2018-05-24 Gojo Industries, Inc. Antimicrobial peptide stimulating sanitizing composition
CN110191916B (zh) * 2016-11-28 2022-06-03 陶氏东丽株式会社 海绵形成性液状有机硅橡胶组合物及有机硅橡胶海绵
EP3606343A1 (en) 2017-04-04 2020-02-12 Gojo Industries Inc Methods and compounds for increasing virucidal efficacy in hydroalcoholic systems
DE102018200732A1 (de) 2018-01-17 2019-07-18 B. Braun Melsungen Ag Zusammensetzung zur Desinfektion von Haut und/oder Händen
WO2019215679A1 (en) 2018-05-10 2019-11-14 Protair-X Health Solutions, Inc. Foam sanitizer composition
EP3636733B1 (en) 2018-10-12 2022-09-21 Wacker Metroark Chemicals Pvt. Ltd. Silicone composition and its application as an additive in detergent composition to enhance foamability and cleaning effect
US20220354756A1 (en) 2019-07-24 2022-11-10 Shiseido Company, Ltd. A water-in-oil emulsion with emollient and methods of using the same
CN110664623A (zh) * 2019-11-18 2020-01-10 浙江绿岛科技有限公司 一种气雾型无酒精免洗抗菌洗手液及其制备方法
JP2023510473A (ja) 2020-01-22 2023-03-14 株式会社 資生堂 化粧料組成物
CA3107420A1 (en) 2020-02-07 2021-08-07 Op-Hygiene Ip Gmbh Ozone foam for treating dermatitis
JP2023529289A (ja) * 2020-05-14 2023-07-10 クェーカー・ケミカル・コーポレーション 水溶性シリコーン系離型剤
WO2021260141A1 (en) 2020-06-26 2021-12-30 Ineos Services Belgium Sa Composition
WO2023121662A1 (en) * 2021-12-22 2023-06-29 Janis Isabel Carreras A skin protectant
CN115594854A (zh) * 2022-10-18 2023-01-13 扬州工业职业技术学院（Cn） 一种含硅可降解型表面活性剂及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857302A (en) * 1987-02-20 1989-08-15 Decker Jr Donald F Solubilized benzoyl peroxide and cosmetic solution including solubilized benzoyl peroxide
CN1284853A (zh) * 1997-11-05 2001-02-21 宝洁公司 适于头发定型的个人护理组合物
CN101198308A (zh) * 2005-06-13 2008-06-11 3M创新有限公司 可起泡的醇组合物、体系和使用方法

Family Cites Families (224)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US638505A (en) * 1899-06-21 1899-12-05 Burt H Whiteley Car-coupling.
US638997A (en) * 1899-10-04 1899-12-12 Nicholas Stock Furniture-pad.
US2096837A (en) 1936-02-11 1937-10-26 Bertram E Baker Carton
US2198354A (en) 1937-01-09 1940-04-23 Briggs Mfg Co Motor vehicle
US2301989A (en) 1940-07-17 1942-11-17 Andrew M Zamborsky Detecting mechanism for fire alarm box
BE449000A (zh) 1942-04-04
US2410796A (en) 1942-04-11 1946-11-05 May & Baker Ltd Soluble amidine salts
US2396742A (en) 1942-12-02 1946-03-19 Milliken Humphreys Circuit breaker
US2444870A (en) 1943-05-31 1948-07-06 Wingfoot Corp Copolymers of butadienes-1, 3 and alpha aryl acrylonitriles
US2436414A (en) 1943-10-25 1948-02-24 Asea Ab Rotor for asynchronous machines
US2516816A (en) 1944-06-19 1950-07-25 Harold A Wagner Power-driven vehicle apparatus
US2596994A (en) 1944-12-09 1952-05-20 Ernest R Haberland Fluxmeter alarm
US2472564A (en) 1945-07-13 1949-06-07 Monroe Calculating Machine Actuator controlling means for calculating machines
GB620508A (en) 1945-08-24 1949-03-25 William Joseph O Brien Improvements in or relating to multiple channel radio receivers
US2523207A (en) 1946-01-14 1950-09-19 Fowler Overhead door
US2600854A (en) 1946-01-22 1952-06-17 Alvin C Cross Leveler attachment for disk harrows
US2539987A (en) 1946-09-19 1951-01-30 Lansing Bagnall Ltd Electrically operated truck and battery charging control therefor
US2533950A (en) 1947-01-17 1950-12-12 Thomas B Mccormick Individual mounting for steerable wheels
US2595025A (en) 1947-08-23 1952-04-29 James C Tripplehorn Spiraled paraffin remover for oil wells
US2487270A (en) 1947-11-05 1949-11-08 Aluminum Co Of America Producing beryllium fluoride
CH276381A (fr) 1948-02-19 1951-07-15 Butin Emile Achille Métier à tisser à changement automatique de navettes.
US2647311A (en) 1951-03-07 1953-08-04 Bard Parker Company Inc Detachable blade pocketknife
US3787566A (en) 1969-07-29 1974-01-22 Holliston Labor Inc Disinfecting aerosol compositions
GB1533119A (en) 1975-04-10 1978-11-22 Unilever Ltd Skin lightening compositions
US4258052A (en) 1976-08-17 1981-03-24 Yu Ruey J Treatment of psoriasis with nicotinamide analogues
DE2728921C3 (de) 1977-06-27 1984-07-05 Dragoco Gerberding & Co Gmbh, 3450 Holzminden Verwendung von Farnesol als Bakteriostatikum in Körperdesodorantien
US4336151A (en) 1981-07-06 1982-06-22 American Cyanamid Company Disinfectant/cleanser compositions exhibiting reduced eye irritancy potential
US4511486A (en) 1981-11-02 1985-04-16 Richardson-Vicks Inc. Method of cleaning dentures using aerated foams
EP0084907B1 (en) 1982-01-26 1986-03-12 Agfa-Gevaert N.V. Apparatus for the liquid processing of a surface of a material in the form of a sheet, a web or a plate
DE3215835A1 (de) 1982-04-28 1983-11-03 Bayer Ag, 5090 Leverkusen Neue treibmittelkombination auf basis von azodicarbonamid, deren herstellung und verwendung der verschaeumung von kunststoffen
GB8330969D0 (en) 1983-11-21 1983-12-29 Wellcome Found Promoting healing
US4758599A (en) 1986-06-04 1988-07-19 American Cyanamid Company Clear, hydroalcoholic aftershave lotion which moisturizes, conditions, and prevents irritation
US5256401A (en) 1987-01-30 1993-10-26 Colgate-Palmolive Company Antibacterial antiplaque mouthwash composition
US5047249A (en) 1988-07-22 1991-09-10 John Morris Co., Inc. Compositions and methods for treating skin conditions and promoting wound healing
FR2646080B1 (fr) 1989-04-21 1991-07-19 Oreal Composition cosmetique contenant des composes obtenus par culture de cellules, notamment de fibroblastes ou de keratinocytes
US5015228A (en) 1989-06-05 1991-05-14 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
US5560859A (en) 1989-07-26 1996-10-01 Pfizer Inc. Post foaming gel shaving composition
JP2961556B2 (ja) 1990-06-15 1999-10-12 丸石製薬株式会社 皮膚消毒用組成物
FR2668366B1 (fr) 1990-10-30 1993-01-29 Oreal Utilisation cosmetique d'une composition ayant une activite antierythemale et composition correspondante.
US5073371A (en) 1990-11-30 1991-12-17 Richardson-Vicks, Inc. Leave-on facial emulsion compositions
US5167950A (en) 1991-03-28 1992-12-01 S. C. Johnson & Son High alcohol content aerosol antimicrobial mousse
US5254331A (en) 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
USD338585S (en) 1991-10-07 1993-08-24 Gojo Industries, Inc. Dispenser
CA2093627A1 (en) 1992-04-13 1993-10-14 Angel A. Guerrero Cosmetic composition
USD343751S (en) 1992-05-04 1994-02-01 Gojo Industries, Inc. Dispenser for soap or similar viscous material
US5465877A (en) 1992-09-08 1995-11-14 Gojo Industries, Inc. Adjustable stroke pump dispenser
US5265772A (en) 1992-10-19 1993-11-30 Gojo Industries, Inc. Dispensing apparatus with tube locator
USD346332S (en) 1993-01-25 1994-04-26 Gojo Industries, Inc. Container
US5462688A (en) 1993-08-20 1995-10-31 Gojo Industries, Inc. Flowable, pumpable cleaning compositions and method for the preparation thereof
US5370267A (en) 1993-10-04 1994-12-06 Gojo Industries Inc. Method and apparatus for measuring dispenser usage
USD365509S (en) 1994-02-15 1995-12-26 Gojo Industries, Inc. Mounting bracket for a container
USD365518S (en) 1994-02-15 1995-12-26 Gojo Industries, Inc. Overcap for a dispenser
US5441178A (en) 1994-04-25 1995-08-15 Gojo Industries, Inc. Overcap for pump style dispenser
JP3568578B2 (ja) * 1994-04-25 2004-09-22 フマキラー株式会社 ヨノン骨格を有するチオシアナート化合物誘導体及びそれを用いた殺菌剤
US5587358A (en) 1994-05-09 1996-12-24 Asahi Kasei Kogyo Kabushiki Kaisha Potentiators of antimicrobial activity
US5523014A (en) 1994-05-16 1996-06-04 Gojo Industries, Inc. Flowable, pumpable cleaning compositions and method for the preparation thereof
US5449137A (en) 1994-05-16 1995-09-12 Gojo Industries, Inc. Dispensing bottle mounting bracket
WO1995031962A1 (en) 1994-05-20 1995-11-30 Gojo Industries, Inc. Antimicrobial cleaning composition containing chlorhexidine, anamphoteric and an alkylpolyglucoside
CA2151774C (en) 1994-06-27 1999-04-06 Minh Quang Hoang Skin disinfecting formulations
US5635462A (en) 1994-07-08 1997-06-03 Gojo Industries, Inc. Antimicrobial cleansing compositions
USD365755S (en) 1994-11-25 1996-01-02 Gojo Industries, Inc. Dispensing container
DE19504999A1 (de) 1995-02-15 1996-08-22 Hoechst Ag Verfahren zur Hemmung sorbatinduzierter Braunverfärbung in kosmetischen Mitteln und Lebensmitteln sowie sorbatkonservierte, farbstabilisierte Formulierungen
USD383001S (en) 1995-05-18 1997-09-02 Gojo Industries, Inc. Bottle and brush combination
USD400799S (en) 1995-05-18 1998-11-10 Gojo Industries, Inc. Combined bottle and cap
US5558453A (en) 1995-05-18 1996-09-24 Gojo Industries, Inc. Container and applicator combination
US5625659A (en) 1995-05-19 1997-04-29 Gojo Industries, Inc. Method and apparatus for electronically measuring dispenser usage
US6623744B2 (en) 1995-06-22 2003-09-23 3M Innovative Properties Company Stable hydroalcoholic compositions
CA2224798A1 (en) 1995-06-22 1997-01-09 Matthew T. Scholz Stable hydroalcoholic compositions
JP4497559B2 (ja) 1995-06-22 2010-07-07 スリーエム カンパニー 安定なヒドロアルコール組成物
DE19523320A1 (de) 1995-06-27 1997-01-02 Henkel Ecolab Gmbh & Co Ohg Terpenhaltige Desinfektionsmittel-Konzentrate und ihre Verwendung
DE19531893A1 (de) 1995-08-30 1997-03-06 Bayer Ag Juckreizmildernde, kosmetische und/oder pharmazeutische Zusammensetzungen
US5939082A (en) 1995-11-06 1999-08-17 The Procter & Gamble Company Methods of regulating skin appearance with vitamin B3 compound
US5833998A (en) 1995-11-06 1998-11-10 The Procter & Gamble Company Topical compositions for regulating the oily/shiny appearance of skin
US5759524A (en) 1996-02-09 1998-06-02 The Procter & Gamble Company Photoprotective compositions
US5718353A (en) 1996-05-08 1998-02-17 Gojo Industries, Inc. Towelette dispensing closure assembly
US5725131A (en) 1996-05-24 1998-03-10 Gojo Industries, Inc. Powder dispensing dispenser valve and dispensing assembly
JP3295596B2 (ja) 1996-05-31 2002-06-24 日東工器株式会社 油圧駆動工具制御装置
USD385795S (en) 1996-10-09 1997-11-04 Gojo Industries, Inc. Liquid container
JP2001506492A (ja) 1996-12-05 2001-05-22 ヒューマン ゲノム サイエンシズ インク． ヒトケモカインβ−１３
US6582711B1 (en) 1997-01-09 2003-06-24 3M Innovative Properties Company Hydroalcoholic compositions thickened using polymers
USD392136S (en) 1997-04-07 1998-03-17 Gojo Industries, Inc. Soap dispenser
US5997890A (en) 1997-05-23 1999-12-07 The Procter & Gamble Company Skin care compositions and method of improving skin appearance
US5968528A (en) 1997-05-23 1999-10-19 The Procter & Gamble Company Skin care compositions
EP0882446A1 (en) 1997-06-02 1998-12-09 Gojo Industries,Inc. Antimicrobial skin cleansing compositions
US5997887A (en) 1997-11-10 1999-12-07 The Procter & Gamble Company Skin care compositions and method of improving skin appearance
US20020022660A1 (en) 1998-01-20 2002-02-21 Hanuman B. Jampani Deep penetrating antimicrobial compositions
US6022551A (en) 1998-01-20 2000-02-08 Ethicon, Inc. Antimicrobial composition
US6130253A (en) 1998-01-27 2000-10-10 Ximed Group Plc Terpene based pesticide treatments for killing terrestrial arthropods including, amongst others, lice, lice eggs, mites and ants
EP1063963A1 (en) 1998-03-16 2001-01-03 The Procter & Gamble Company Method of reducing cellulite in mammalian skin
US5989523A (en) 1998-03-20 1999-11-23 Fitzjarrell; Edwin A. Topical spray for treating acne containing niacinamide and NaPCA
US6319958B1 (en) 1998-06-22 2001-11-20 Wisconsin Alumni Research Foundation Method of sensitizing microbial cells to antimicrobial compound
USD416417S (en) 1998-06-26 1999-11-16 Gojo Industries, Inc. Wall mounted dispenser for liquids
US5944227A (en) 1998-07-06 1999-08-31 Gojo Industries, Inc. Dispenser for multiple cartridges
EP2305825B1 (en) 1998-07-06 2015-01-14 DCV Inc. doing business as Bio-Technical Resourses Method of vitamin production
US8106094B2 (en) 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
USD418708S (en) 1998-07-17 2000-01-11 Gojo Industries, Inc. Container holder
USD411456S (en) 1998-08-31 1999-06-22 Gojo Industries, Inc. Bottle
US20030147925A1 (en) 1998-09-11 2003-08-07 Samuel P. Sawan Topical dermal antimicrobial compositions, methods for generating same, and monitoring methods utilizing same
US6333039B1 (en) 1998-09-25 2001-12-25 Gojo Industries, Inc. Opaque skin sanitizing composition
US5996851A (en) 1998-09-28 1999-12-07 Gojo Industries, Inc. Bladder-operated dispenser
US6149925A (en) 1998-11-05 2000-11-21 Color Access, Inc. Topical compositions for enhancing glutathione production
US6344218B1 (en) 1998-11-23 2002-02-05 The Procter & Gamble Company Skin deodorizing and santizing compositions
USD415343S (en) 1998-12-04 1999-10-19 Gojo Industries, Inc. Belt clip
US6183766B1 (en) 1999-02-12 2001-02-06 The Procter & Gamble Company Skin sanitizing compositions
US6309657B2 (en) 1999-02-12 2001-10-30 The Procter & Gamble Company Cosmetic compositions
US6423329B1 (en) 1999-02-12 2002-07-23 The Procter & Gamble Company Skin sanitizing compositions
US6224888B1 (en) 1999-02-12 2001-05-01 The Procter & Gamble Company Cosmetic compositions
US6065639A (en) 1999-02-26 2000-05-23 Gojo Industries, Inc. Multiple use wash counter and timer
USD422828S (en) 1999-06-07 2000-04-18 Gojo Industries, Inc. Container holder and wall-mounting bracket for same
US6274124B1 (en) 1999-08-20 2001-08-14 Dragoco Gerberding & Co. Ag Additive for improving the water resistance of cosmetic or dermatological formulations
US6265363B1 (en) 1999-10-27 2001-07-24 Gojo Industries, Inc. Skin cleansing composition for removing ink
US20080254150A1 (en) 2000-01-03 2008-10-16 Rheins Lawrence A Management of dermatitic symptoms of mammalian integument with emollient disinfectant formulations
KR100331219B1 (ko) 2000-02-10 2002-04-06 이상원 인터넷 과금방법 및 시스템
US6267976B1 (en) 2000-04-14 2001-07-31 Gojo Industries, Inc. Skin cleanser with photosensitive dye
US20020022040A1 (en) 2000-07-10 2002-02-21 The Proctor & Gamble Company Methods of enhancing delivery of oil-soluble skin care actives
JP3450805B2 (ja) 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
US6383505B1 (en) 2000-11-09 2002-05-07 Steris Inc Fast-acting antimicrobial lotion with enhanced efficacy
US6432430B1 (en) 2000-11-17 2002-08-13 Edwin Fitzjarrell Exfoliating scrub with niacinamide
CN1313070C (zh) 2001-01-16 2007-05-02 荷兰联合利华有限公司 口腔用组合物
KR100674423B1 (ko) 2001-01-19 2007-01-29 엘지전자 주식회사 송/수신 시스템 및 데이터 처리 방법
ES2275808T3 (es) 2001-02-06 2007-06-16 Pfizer Products Inc. Composiciones farmaceuticas para el tratamiento de trastornos del snc y otros trastornos.
WO2002067889A2 (en) 2001-02-22 2002-09-06 Unilever Plc Skin composition for reducing skin oils and grease
MXPA03008869A (es) 2001-03-29 2004-05-24 Dial Corp Composiciones antibacterianas para el cuidado de la piel.
MXPA03010860A (es) 2001-05-30 2004-02-17 Procter & Gamble COMPOSICION TOPICA QUE COMPRENDE UN AGENTE DE UNION COSMeTICO SUSTITUIDO.
CN1536984A (zh) 2001-05-30 2004-10-13 包括活化的反式结构的化妆品键合剂的局部组合物
US7007025B1 (en) 2001-06-08 2006-02-28 Xsides Corporation Method and system for maintaining secure data input and output
US6383997B1 (en) 2001-07-02 2002-05-07 Dragoco Gerberding & Co. Ag High lathering antibacterial formulation
US7166435B2 (en) 2001-08-06 2007-01-23 The Quigley Corporation Compositions and methods for reducing the transmissivity of illnesses
GB0119831D0 (en) 2001-08-14 2001-10-10 Unilever Plc Dual compartment packaged cosmetic composition
US6846846B2 (en) 2001-10-23 2005-01-25 The Trustees Of Columbia University In The City Of New York Gentle-acting skin disinfectants
US7147873B2 (en) 2002-01-16 2006-12-12 3M Innovative Properties Company Antiseptic compositions and methods
JP4015934B2 (ja) 2002-04-18 2007-11-28 株式会社東芝 動画像符号化方法及び装置
US8329758B2 (en) 2002-02-05 2012-12-11 Gojo Industries, Inc. Skin sanitizing antimicrobial alcoholic compositions
US6763875B2 (en) 2002-02-06 2004-07-20 Andersen Corporation Reduced visibility insect screen
AU2003216213B2 (en) 2002-02-07 2008-10-02 The Trustees Of Columbia University In The City Of New York Zinc salt compositions for the prevention of mucosal irritation from spermicides and microbicides
US20040001797A1 (en) 2002-06-21 2004-01-01 Abel Saud Antimicrobial compositions, products and methods employing same
US7569530B1 (en) 2003-06-20 2009-08-04 The Procter & Gamble Company Antimicrobial compositions, products and methods employing same
CN100342917C (zh) 2002-08-20 2007-10-17 Alda医药公司 一种广谱消毒剂
US20060193789A1 (en) 2002-10-25 2006-08-31 Foamix Ltd. Film forming foamable composition
US6979468B1 (en) 2002-12-06 2005-12-27 Sirius Laboratories Oral composition and method for the treatment of inflammatory cutaneous disorders
US6723689B1 (en) 2003-01-08 2004-04-20 Becton Dickinson And Company Emollient alcohol skin disinfecting formulation
CA2424003A1 (en) 2003-03-28 2004-09-28 Austin & Repatriation Medical Centre Anti-microbial topical composition comprising alcohol and chlorhexidine salt
US20050058673A1 (en) 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
CN1867251A (zh) 2003-09-09 2006-11-22 3M创新有限公司 抗菌组合物和方法
KR20060113907A (ko) 2003-09-29 2006-11-03 에테나 헬스케어 인코포레이티드 높은 알코올 함량의 겔-유사 및 포옴 조성물
US7378451B2 (en) 2003-10-17 2008-05-27 3M Innovative Properties Co Surfactant composition having stable hydrophilic character
US20050209181A1 (en) 2003-11-05 2005-09-22 Huda Akil Compositions and methods for diagnosing and treating mental disorders
US20050112084A1 (en) 2003-11-21 2005-05-26 The Gillette Company Topical cosmetic composition
US20050142079A1 (en) 2003-12-26 2005-06-30 Garrison Mark S. Oil in silicone emulsion and compositions containing same
FR2869229B1 (fr) 2004-04-26 2006-08-25 Sederma Soc Par Actions Simpli Utilisation d'un inducteur des ugt par voie topique
US20060051384A1 (en) 2004-09-07 2006-03-09 3M Innovative Properties Company Antiseptic compositions and methods of use
US20060062832A1 (en) 2004-09-20 2006-03-23 Lopes John A Sanitizing wipes with microbicidal properties cross-reference to related applications
HUE045022T2 (hu) 2004-09-27 2019-12-30 Special Water Patents B V Eljárások és kompozíciók víz kezelésére
US8620249B2 (en) 2004-10-29 2013-12-31 Broadcom Corporation Method and system for process, voltage, and temperature (PVT) measurement and calibration
US20060104919A1 (en) 2004-11-16 2006-05-18 Novak John T Foamable alcohol
US20060104911A1 (en) 2004-11-16 2006-05-18 Novak John T Foamable alcohol
WO2006062847A2 (en) 2004-12-09 2006-06-15 The Dial Corporation Compositions having a high antiviral and antibacterial efficacy
MX2007006860A (es) 2004-12-09 2008-02-15 Dial Corp Composiciones que tienen alta eficacia antiviral y antibacterial.
EP1827099A2 (en) 2004-12-09 2007-09-05 The DIal Corporation Compositions having a high antiviral and antibacterial efficacy
US20100204323A1 (en) 2004-12-09 2010-08-12 The Dial Corporation Antimicrobial compositions comprising organic acid esters and methods for reducing virus and bacterial populations using such compositions
WO2007044032A2 (en) 2004-12-09 2007-04-19 The Dial Corporation Compositions having a high antiviral and antibacterial efficacy
US20080199535A1 (en) 2004-12-09 2008-08-21 The Dial Corporation Compositions Having a High Antiviral and Antibacterial Efficacy
US20090104281A1 (en) 2004-12-09 2009-04-23 The Dial Corporation Compositions Having a High Antiviral and Antibacterial Efficacy
US20090012174A1 (en) 2004-12-09 2009-01-08 The Dial Corporation Compositions Having a High Antiviral and Antibacterial Efficacy
US7521404B2 (en) 2004-12-16 2009-04-21 Georgia-Pacific Consumer Products Lp Antimicrobial liquid hand soap composition with tactile signal comprising a phospholipid surfactant
DE102004062775A1 (de) 2004-12-21 2006-06-29 Stockhausen Gmbh Alkoholischer Pumpschaum
CA2533950C (en) 2005-01-28 2013-10-22 B. Braun Medical Ag Virucidal disinfectant
AU2006222502B2 (en) 2005-03-07 2010-02-11 Deb Ip Limited High alcohol content foaming compositions with silicone-based surfactants
KR20070113284A (ko) 2005-03-10 2007-11-28 쓰리엠 이노베이티브 프로퍼티즈 캄파니 미생물 오염의 감소방법
CA2599667C (en) 2005-03-10 2014-12-16 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxy carboxylic acids
US20060229364A1 (en) 2005-03-10 2006-10-12 3M Innovative Properties Company Antiviral compositions and methods of use
US7435055B2 (en) 2005-03-29 2008-10-14 Siemens Power Generation, Inc. Locking spacer assembly for a turbine engine
EP1707362A3 (en) 2005-03-29 2007-05-02 Toshiba TEC Kabushiki Kaisha Ink jet recording apparatus
US8725646B2 (en) 2005-04-15 2014-05-13 Microsoft Corporation Output protection levels
US7585527B2 (en) 2005-09-19 2009-09-08 Bala Venkataraman Composition and method for treating iron deficiency anemia
US7700083B2 (en) 2005-10-24 2010-04-20 Kevin Meehan Skin care composition for accelerated production of collagen proteins and method of fabricating same
GB0524962D0 (en) 2005-12-07 2006-01-18 Pharmakodex Ltd Topical pharmaceutical compositions
US11717533B2 (en) 2005-12-22 2023-08-08 Swiss-American Cdmo Llc Zinc composition and their use in anti-microbial applications
US20070148101A1 (en) * 2005-12-28 2007-06-28 Marcia Snyder Foamable alcoholic composition
US8450378B2 (en) 2006-02-09 2013-05-28 Gojo Industries, Inc. Antiviral method
US8119115B2 (en) 2006-02-09 2012-02-21 Gojo Industries, Inc. Antiviral method
US20070185216A1 (en) 2006-02-09 2007-08-09 Marcia Snyder Antiviral method
US9629361B2 (en) 2006-02-09 2017-04-25 Gojo Industries, Inc. Composition and method for pre-surgical skin disinfection
US8388992B2 (en) 2006-03-28 2013-03-05 Georgia-Pacific Consumer Products Lp Anti-microbial hand towel with time-delay chromatic transfer indicator and absorbency rate delay
RU2008151178A (ru) 2006-05-24 2010-06-27 Дзе Дайл Корпорейшн (Us) Способы и изделия, обладающие сильным противовирусным и противобактериальным действием
CA2644524A1 (en) 2006-05-25 2007-12-06 The Dial Corporation Method of enhancing the control of viruses on skin
EP2040544A2 (en) 2006-05-26 2009-04-01 The Dial Corporation Method of inhibiting the transmission of viruses
EP2040542A2 (en) 2006-05-30 2009-04-01 The Dial Corporation Compositions having a high antiviral effeicacy
JP2007320952A (ja) * 2006-05-30 2007-12-13 Yasuhara Chemical Co Ltd 抗菌剤組成物
EP2034831A2 (en) 2006-05-31 2009-03-18 The Dial Corporation Alcohol-containing antimicrobial compositions having improved efficacy
US8147877B2 (en) 2006-06-01 2012-04-03 Ohso Clean, Inc. Essential oils based disinfecting compositions having tuberculocidal and fungicidal efficacies
WO2008036134A2 (en) 2006-06-02 2008-03-27 The Dial Corporation Method of inhibiting the transmission of influenza virus
WO2007145886A2 (en) 2006-06-05 2007-12-21 The Dial Corporation Methods and articles having a high antiviral and antibacterial efficacy
AR061727A1 (es) 2006-06-30 2008-09-17 Schering Corp Sintesis de dietil [[ 5- ( 3-fluorofenil) -piridin -2il] metil] fosfonato
US20080026974A1 (en) 2006-07-27 2008-01-31 Barnhart Ronald A Antimicrobial hand wash
WO2008022186A2 (en) 2006-08-15 2008-02-21 Stack Kevin C Antimicrobial sanitizing formulations with skin protection properties
CN102614528B (zh) 2006-08-18 2014-02-26 箭头研究公司 用于体内递送多核苷酸的多缀合物
EP2091324B1 (en) 2006-10-27 2016-12-28 3M Innovative Properties Company Antimicrobial compositions
US7465697B1 (en) 2006-11-02 2008-12-16 Ohsoclean, Inc. Essential oils based cleaning and disinfecting compositions
ITMI20062253A1 (it) * 2006-11-24 2008-05-25 Nuova Pansac Spa Materiale in film con riporto igienizzante e-o assorbiodori
US9555167B2 (en) 2006-12-11 2017-01-31 3M Innovative Properties Company Biocompatible antimicrobial compositions
US20080200890A1 (en) 2006-12-11 2008-08-21 3M Innovative Properties Company Antimicrobial disposable absorbent articles
US8580860B2 (en) 2007-02-23 2013-11-12 Gojo Industries, Inc. Foamable alcoholic composition
US8333954B2 (en) 2007-04-30 2012-12-18 Kimberly-Clark Worldwide, Inc. Foamable sanitizing compositions
JP2009009234A (ja) 2007-06-26 2009-01-15 Kyocera Mita Corp 画像処理装置
US20090046116A1 (en) 2007-08-15 2009-02-19 Pitney Bowes Inc. Print architecture for driving multiple print heads
US8053399B2 (en) * 2007-08-30 2011-11-08 Kimberly-Clark Worldwide, Inc. Foamable compositions
US7973006B2 (en) 2007-09-17 2011-07-05 Purac Biochem B.V. Antibacterial agent based on fatty acid esters of hydroxy carboxylic acid acids
US8980344B2 (en) 2007-10-01 2015-03-17 Dennis F. Gross Skin care products containing multiple enhancers
ES2371416T3 (es) 2007-10-10 2012-01-02 Ep Systems Sa Sistema de control de accionador piezoeléctrico adaptativo.
ES2383253T5 (es) 2007-10-30 2015-03-06 Gojo Ind Inc Composiciones de geles hidroalcohólicos para uso con dispensadores
AU2008347253B2 (en) 2007-12-31 2012-04-19 3M Innovative Properties Company Antimicrobial compositions
US10589134B2 (en) 2008-01-30 2020-03-17 Kimberly-Clark Worldwide, Inc. Hand health and hygiene system for hand health and infection control
US20120208894A1 (en) 2008-03-17 2012-08-16 Bode Chemie Gmbh & Co. Kg Multi-purpose hand disinfectant
US8918328B2 (en) 2008-04-18 2014-12-23 Yahoo! Inc. Ranking using word overlap and correlation features
US8119698B2 (en) 2008-06-30 2012-02-21 Conopco, Inc. Sunscreen formula vanishing cream
US20090324661A1 (en) 2008-06-30 2009-12-31 Conopco, Inc., D/B/A Unilever Niacinamide containing cosmetic compositions with improved skinfeel properties
US20100003198A1 (en) 2008-07-07 2010-01-07 Patrick John Stolmeier Antimicrobial Topical and Other Preparations Containing Fluorescent or Illumination Dye and Tracer Agents or Compounds
US7842725B2 (en) * 2008-07-24 2010-11-30 Ecolab USA, Inc. Foaming alcohol compositions with selected dimethicone surfactants
US20120164087A1 (en) 2009-04-24 2012-06-28 Carter Daniel C Human Serum Albumin-Based Topical Ointment for Treatment of Acne, Psoriasis, Egfr-Induced Toxicity, Premature Skin Aging and Other Skin Conditions
TW201113091A (en) 2009-06-15 2011-04-16 Gojo Ind Inc Methods and compositions for use with gel dispensers
GB0912481D0 (en) 2009-07-17 2009-08-26 Reckitt Benckiser Healthcare I Skincare compositions
FR2948565B1 (fr) 2009-07-30 2011-10-28 Expanscience Lab Composition cosmetique pour le traitement de l'acne comprenant un extrait petidique de schizandra
JP2012018486A (ja) 2010-07-06 2012-01-26 Toshiba Corp 情報処理装置およびユーザインタフェースの表示位置制御法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857302A (en) * 1987-02-20 1989-08-15 Decker Jr Donald F Solubilized benzoyl peroxide and cosmetic solution including solubilized benzoyl peroxide
CN1284853A (zh) * 1997-11-05 2001-02-21 宝洁公司 适于头发定型的个人护理组合物
CN101198308A (zh) * 2005-06-13 2008-06-11 3M创新有限公司 可起泡的醇组合物、体系和使用方法

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