CN105361944A - Ablation catheter and method using same to implement ablation - Google Patents
Ablation catheter and method using same to implement ablation Download PDFInfo
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- CN105361944A CN105361944A CN201410427855.2A CN201410427855A CN105361944A CN 105361944 A CN105361944 A CN 105361944A CN 201410427855 A CN201410427855 A CN 201410427855A CN 105361944 A CN105361944 A CN 105361944A
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- ablation
- microwave signal
- ablating electrode
- catheter
- ablation catheter
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Abstract
The invention provides an ablation catheter and a method using the same to implement ablation. The ablation catheter comprises an ablation electrode, a catheter body, an operation handle and a control processing system which are connected sequentially, the control processing system comprises a radio frequency transmitting system and a microwave signal processing system, the radio frequency transmitting system sends out an ablation radio frequency signal which is transmitted to ablation tissue through the ablation electrode, the ablation electrode receives a microwave signal from the ablation tissue and transmits the microwave signal to the microwave signal processing system, and the ablation electrode can serve as a transmitting antenna of the ablation radio frequency signal and a receiving antenna of the microwave signal, so that temperature change of the ablation tissue can be presented truly and timely without affecting controllability of the catheter. The ablation catheter is simple in machining process and low in cost, and operating safety is improved to some extent.
Description
Technical field
The present invention relates to technical field of medical instruments, be specifically related to a kind of ablation catheter and utilize this ablation catheter to implement the method melted.
Background technology
Now, utilize catheter ablation technique to treat such as arrhythmia, the diseases such as intractable hypertension become possibility.Such as radio-frequency ablation procedure is the specific part being needed through vein or arteries feeding by the ablation catheter with electrode to melt, and causes the tissue coagulation of local downright bad, reach the propagation of blocking-up aberrant electrical signals or block sympathetic nerve by release radio-frequency current.In radio-frequency ablation procedure, be the necrosis being made local organization coagulability by heat tissue, therefore, the control of tissue temperature seemed particularly important.When the temperature is too low, as being less than 50 degree, tissue is difficult to formation and effectively melts stove, and namely electric signal isolation is incomplete; When temperature is too high, as being greater than 80 degree, tissue temperature is too high, easily forms thrombosis.Therefore, in heating process, it is very necessary for monitoring the variations in temperature of ablation tissue.
At the far-end of ablation catheter, temperature sensor is housed at present, indirectly can experiences the variations in temperature from ablation tissue.Along with the development of cold brine perfusion technology, namely in ablation procedure, perfusion cooling is carried out to electrode, effectiveness and the safety of operation can be improved widely.But perfusion technique makes the effect losing monitoring ablation tissue temperature in the temperature sensor of distal end of catheter, and temperature sensor is shown as the temperature of cool brine all the time.
Therefore, in ablation procedure, if the temperature of tissue can be obtained in real time, exactly, do not affect the handling of ablation catheter again, very important effect will be played to ablation effect.
Summary of the invention
The object of the present invention is to provide a kind of method that ablation catheter and enforcement thereof are melted, the change of ablation tissue temperature can be reacted truly, in real time, and processing technique is simple, cost is low.
For achieving the above object and other relevant object, the invention provides a kind of ablation catheter: comprise the ablating electrode, catheter main body, operating grip and the control treatment system that connect successively, wherein, described control treatment system comprises RF emission system and microwave signal process system, described RF emission system sends and melts radiofrequency signal, reaches ablation tissue via described ablating electrode; Described ablating electrode receives the microwave signal from ablation tissue, and reaches described microwave signal process system
Optionally, described control treatment system also comprises the time-sharing circuit be connected with ablating electrode, controls to melt radiofrequency signal and microwave signal alternate transport.
Optionally, described microwave signal process system comprises interconnective signal amplification module and filtration module.
Optionally, also comprise the filling system being extended to ablating electrode by operating grip, perfusion cooling is carried out to described ablating electrode.
Optionally, described control treatment system also comprises display module, the variations in temperature of display ablating electrode.
Optionally, described ablating electrode is connected with microwave signal process system with RF emission system respectively by coaxial line.
Optionally, described ablating electrode is connected with microwave signal process system with RF emission system respectively by two wires.
Optionally, described ablating electrode is cylindric, and material is gold, platinum or platinumiridio.
Optionally, the described ablating electrode base that comprises shell body and be connected with described shell body.
Optionally, described shell body is provided with multiple apopore, is communicated with described filling system.
Optionally, described base is provided with multiple inner cavity, places bracing wire and wire respectively.
Optionally, described base also arranges pass through aperture, for holding the intrusion pipe of described filling system.
Optionally, also comprising can the section of deflection, and the described section of deflection includes multi-lumen tube.
Optional described radiofrequency signal be spaced apart 1ms ~ 500ms, the time of melting is 1ms ~ 500ms.
Accordingly, the present invention also provides a kind of ablation catheter to implement the method melted, and adopts above-mentioned ablation catheter to implement to melt, comprising: control operation handle, ablating electrode and catheter main body is entered in human body and close to ablation tissue; Under the effect of control treatment system, RF emission system sends and melts radiofrequency signal and reach the object melted; Meanwhile, ablating electrode alternately accepts the microwave signal sent from ablation tissue, transfers to described microwave signal process system, converts microwave signal to temperature signal, thus the variations in temperature of reflection ablation tissue.
Optionally, time-sharing circuit alternately controls the transmitting of described ablating electrode and melts radiofrequency signal, and accepts described microwave signal.
Compared with prior art, the beneficial effect of ablation catheter provided by the present invention and ablation method thereof is:
1, the present invention by arranging RF emission system and microwave signal process system in the control treatment system of ablation catheter, described RF emission system sends and melts radiofrequency signal, ablation tissue is reached via described ablating electrode, described ablating electrode receives the microwave signal from ablation tissue, and reach described microwave signal process system, described ablating electrode can simultaneously as the reception antenna of the transmitting antenna and microwave signal that melt radiofrequency signal, thus truly, in time react the change of ablation tissue temperature, and the handling of conduit can not be affected; Further, ablation catheter provided by the present invention, processing technique is simple, and cost is low, the safety of the operation improved to a certain extent;
2, the present invention is provided with time-sharing circuit in control treatment system, can effectively isolate radio-frequency (RF) ablation signal and microwave signal, make radio-frequency (RF) ablation signal and microwave signal alternate transport, avoid as prior art, use the devices such as frequency division antenna diplexer, reduce difficulty of processing.
Accompanying drawing explanation
The schematic diagram of the ablation catheter that Fig. 1 provides for one embodiment of the invention.
The profile of one end of ablating electrode is included in the ablation catheter that Fig. 2 provides for another embodiment of the present invention.
The sectional view of one end of ablating electrode is included in the ablation catheter that Fig. 3 provides for another embodiment of the present invention.
The Time-sharing control schematic diagram of ablation catheter in ablation procedure that Fig. 4 provides for another embodiment of the present invention.
The device schematic diagram of time-sharing circuit in the ablation catheter that Fig. 5 provides for another embodiment of the present invention.
The device schematic diagram of time-sharing circuit in the ablation catheter that Fig. 6 provides for another embodiment of the present invention.
Detailed description of the invention
For making content of the present invention clearly understandable, below in conjunction with Figure of description, content of the present invention is described further.Certain the present invention is not limited to this specific embodiment, and the general replacement known by those skilled in the art is also encompassed in protection scope of the present invention.
Secondly, the present invention's detailed statement that utilized schematic diagram to carry out, when describing example of the present invention in detail, for convenience of explanation, schematic diagram, should to this as restriction of the present invention not according to general ratio partial enlargement.
Core concept of the present invention is: in control treatment system, arrange RF emission system and microwave signal process system, described RF emission system sends and melts radiofrequency signal, ablation tissue is reached via described ablating electrode, described ablating electrode receives the microwave signal from ablation tissue, and reach described microwave signal process system, described ablating electrode can simultaneously as the reception antenna of the transmitting antenna and microwave signal that melt radiofrequency signal, thus truly, in time react the change of ablation tissue temperature, and the handling of conduit can not be affected.
Please refer to Fig. 1, the schematic diagram of its ablation catheter provided for one embodiment of the invention.As shown in Figure 1, described ablation catheter 10 comprises the ablating electrode 11, catheter main body 13, operating grip 14 and the control treatment system 15 that connect successively, described control treatment system 15 comprises RF emission system 151 and microwave signal process system 152, described RF emission system 151 sends and melts radiofrequency signal, reaches ablation tissue via described ablating electrode 11; Described ablating electrode 11 receives the microwave signal from ablation tissue, and reaches described microwave signal process system 152.
In the present embodiment, the diameter of described ablation catheter 10 or catheter main body 13 is less than or equal to 3mm, length is 70cm ~ 200cm, the main material of described ablation catheter 10 is macromolecular material, can be block polyetheramides elastomer (PEBAX), Polyurethane Thermoplastic Elastomer (TPU), also can be the TPU with woven wire cloth.The material of described ablating electrode 11 is metal material, is preferably gold, platinum or platinumiridio.Described ablating electrode 11 is cylindrical.
As shown in Figure 2 and Figure 3, comprising in another embodiment can the section of deflection 12, and the described section of deflection 12 includes multi-lumen tube, the described section of deflection 12 is also provided with ring electrode wire 121, the profile of its ablation catheter provided for the present embodiment and sectional view.
Described control treatment system 15 also comprises filling system 153; Described RF emission system 151 sends and melts radiofrequency signal, make local organization coagulation necrosis in human body, reach the object melted, describedly melt the square wave that radiofrequency signal is frequency 500KHz, the microwave signal that described microwave signal process system 152 receiving range ablating electrode 3mm ~ 5mm place organizes self to send, the microwave signal scope accepted is 1GHz-10GHz, is preferably 4GHz; Described filling system 153 gives ablating electrode 11 and pours into, to reduce the temperature of ablation procedure ablating electrode 11.Described RF emission system 151, microwave signal process system 152 and filling system 153 all can be undertaken unifying process by processing system 154, and mutually coordinate, regulate parameters by control system 155, each is measured the parameter obtained and can show on display module 156.
The base 112 that described ablating electrode 11 comprises shell body 111 and is connected with described shell body 111.Described shell body 111 is provided with multiple apopore 1110, flows out for fluid, be communicated with filling system; The diameter of described apopore 1110 is 0.05mm ~ 0.3mm, such as 0.05mm, 0.07mm, 0.09mm, 0.1mm, 0.15mm, 0.2mm, 0.25mm, 0.3mm, is preferably 0.09mm; The quantity of described apopore 1110 is 6 ~ 100, such as 6,36,66,96,100, is preferably 66.Described base 112 is provided with multiple inner cavity, places wire 1121 and bracing wire 1122 respectively, wherein, the inner cavity placing described bracing wire 1122 is symmetrical arranged, its hollow depth is 1mm ~ 2mm, such as: 1mm, 1.2mm, 1.5mm, 1.7mm, 2mm, is preferably 1.2mm; The hollow depth placing the inner cavity of wire 1121 is 2mm ~ 3mm, such as 2mm, 2.4mm, 2.7mm, 3mm, is preferably 2.4mm.Described base 112 is also provided with a through hole, for holding the intrusion pipe 1123 of filling system, provide cool brine, cool brine enters ablating electrode 11 through described intrusion pipe 1123, sprayed by the apopore 1110 on shell body 111 again, in ablation procedure, ablating electrode 11 is lowered the temperature; Described base 112 is also provided with a boss, boss is welded with coaxial line 1124, its effect is the microwave signal that transmission ablating electrode 11 receives, another effect of described boss is the assembling coordinating catheter main body 13, described ablating electrode 11 can be gluing with the connected mode of catheter main body 13, also can use ratio-frequency welding, and the shell body 111 of described ablating electrode 11 and base 112 can be fetched by electric resistance welding and be connected, also ratio-frequency welding can be passed through, or gluing mode.
Described RF emission system 151 and microwave signal process system 152 can be adopted in two ways with the connection of described ablating electrode 11, one is that described ablating electrode 11 connects coaxial line 1124, described in the tail end of described operating grip 14, coaxial line 1124 accesses described RF emission system 151 and microwave signal process system 152 respectively, described coaxial line 1124 had both transmitted and had melted radiofrequency signal, also transmitted microwave signal; Another kind of: described ablating electrode 11 is connected described RF emission system 151 and microwave signal process system 152 respectively by coaxial line 1124 with wire 1121, described coaxial line 1124 connects described microwave signal process system 152, described wire 1121 connects described RF emission system 151, described coaxial line 1124 carries out the transmission of microwave signal, and described wire 1121 carries out the transmission of melting radiofrequency signal.Therefore, described ablating electrode 11 can melt radiofrequency signal as transmission antennas transmit, also can as the microwave signal accepting antenna and accept ablation tissue self radiation.
In described operating grip 13, be provided with microwave signal process chip, the microwave signal that can receive ablating electrode carries out filter and amplification.Described microwave signal process chip includes one or more signal amplification module and filtration module; The priority position of described signal amplification module and filtration module can change, also can how several groups, such as, can amplify post filtering, or amplify after first filtering, or first filtering, then amplifies, then filtering.
In order to avoid in the process implementing to melt at described ablation catheter 10, melt radiofrequency signal and microwave signal is mutually disturbed on described ablating electrode 11, in described control treatment system 15, time-sharing circuit is set, as shown in Figure 4, melt radiofrequency signal (1) and microwave signal (2) hockets, what melt radiofrequency signal (1) is spaced apart 1ms ~ 500ms, is preferably 5ms ~ 30ms, the time of melting is 1ms ~ 500ms, is preferably 10ms ~ 30ms.
Please refer to Fig. 5 and Fig. 6, described time-sharing circuit includes time controller 50, is connected by described time controller 50 and ablating electrode 11 and RF emission system 151, microwave signal process system 152; Microwave signal with melt radiofrequency signal and transmitted by a coaxial line 1124, controlled by clock switch controller 50, access described RF emission system 151 or microwave signal process system 152 in the different time respectively; As shown in Figure 6, microwave signal with melt radiofrequency signal and transmitted by coaxial line 1124 and wire 1121 respectively, controlled by clock switch controller 60, access described RF emission system 151 or microwave signal process system 152 in the different time.By the setting of time-sharing circuit, distinguish and melt radiofrequency signal and microwave signal, avoid the method using frequency division antenna diplexer in prior art, reduce difficulty of processing.It should be noted that, the setting of time-sharing circuit is not limited to above-mentioned two kinds of modes, and the circuit that can realize timesharing effect well known by persons skilled in the art arranges and is all applicable to this patent.
Accordingly, the present invention also provides a kind of ablation catheter to implement the method melted, adopt above-mentioned ablation catheter to implement to melt, described method comprises: by control operation handle 14, makes ablating electrode 11, can the section of deflection 12 and catheter main body 13 to enter in human body and close to ablation tissue; Under the effect of control treatment system 15, RF emission system 151 sends and melts radiofrequency signal and reach the object melted, simultaneously, ablating electrode 11 alternately accepts the microwave signal that ablation tissue sends, transfer to described microwave signal process system 152, convert microwave signal to temperature signal, thus the variations in temperature of reflection ablation tissue.Further, time-sharing circuit alternately controls the transmitting of described ablating electrode 11 and melts radiofrequency signal, and accepts described microwave signal, makes radio-frequency (RF) ablation signal and microwave signal alternate transport.
In sum, the present invention by arranging RF emission system and microwave signal process system in the control treatment system of ablation catheter, described RF emission system sends and melts radiofrequency signal, ablation tissue is reached via described ablating electrode, described ablating electrode receives the microwave signal from ablation tissue, and reach described microwave signal process system, described ablating electrode can simultaneously as the reception antenna of the transmitting antenna and microwave signal that melt radiofrequency signal, thus truly, in time react the change of ablation tissue temperature, and the handling of conduit can not be affected; Further, ablation catheter provided by the present invention, processing technique is simple, and cost is low, the safety of the operation improved to a certain extent; The present invention is provided with time-sharing circuit in control treatment system, can effectively isolate radio-frequency (RF) ablation signal and microwave signal, make radio-frequency (RF) ablation signal and microwave signal alternate transport, avoid equally using the devices such as frequency division antenna diplexer to prior art, reduce difficulty of processing.
Foregoing description is only the description to present pre-ferred embodiments, any restriction not to the scope of the invention, and any change that the those of ordinary skill in field of the present invention does according to above-mentioned disclosure, modification, all belong to the protection domain of claims.
Claims (16)
1. an ablation catheter, it is characterized in that, comprise the ablating electrode, catheter main body, operating grip and the control treatment system that connect successively, wherein, described control treatment system comprises RF emission system and microwave signal process system, described RF emission system sends and melts radiofrequency signal, reaches ablation tissue via described ablating electrode; Described ablating electrode receives the microwave signal from ablation tissue, and reaches described microwave signal process system.
2. ablation catheter as claimed in claim 1, it is characterized in that, described control treatment system also comprises the time-sharing circuit be connected with ablating electrode, controls to melt radiofrequency signal and microwave signal alternate transport.
3. ablation catheter as claimed in claim 1 or 2, it is characterized in that, described microwave signal process system comprises interconnective signal amplification module and filtration module.
4. ablation catheter as claimed in claim 1 or 2, is characterized in that, also comprise the filling system being extended to ablating electrode by operating grip, carries out perfusion cooling to described ablating electrode.
5. ablation catheter as claimed in claim 1 or 2, it is characterized in that, described control treatment system also comprises display module, the variations in temperature of display ablating electrode.
6. ablation catheter as claimed in claim 1 or 2, it is characterized in that, described ablating electrode is connected with microwave signal process system with RF emission system respectively by coaxial line.
7. ablation catheter as claimed in claim 1 or 2, is characterized in that, described ablating electrode is connected with microwave signal process system with RF emission system respectively by two wires.
8. ablation catheter as claimed in claim 1 or 2, it is characterized in that, described ablating electrode is cylindric, and material is gold, platinum or platinumiridio.
9. ablation catheter as claimed in claim 4, is characterized in that, the base that described ablating electrode comprises shell body and is connected with described shell body.
10. ablation catheter as claimed in claim 9, is characterized in that, described shell body is provided with multiple apopore, be communicated with described filling system.
11. ablation catheters as claimed in claim 9, is characterized in that, described base is provided with multiple inner cavity, place bracing wire and wire respectively.
12. ablation catheters as claimed in claim 9, is characterized in that, described base also arranges pass through aperture, for holding the intrusion pipe of described filling system.
13. ablation catheters as claimed in claim 1, is characterized in that, also comprising can the section of deflection, and the described section of deflection includes multi-lumen tube.
14. ablation catheters as claimed in claim 1 or 2, it is characterized in that, the transmission of described radiofrequency signal is spaced apart 1ms ~ 500ms, and the time of melting is 1ms ~ 500ms.
The method that 15. 1 kinds of ablation catheters are implemented to melt, is characterized in that, adopts ablation catheter according to claim 1 to implement to melt, comprising: control operation handle, ablating electrode and catheter main body is entered in human body and close to ablation tissue; Under the effect of control treatment system, RF emission system sends and melts radiofrequency signal and reach the object melted; Meanwhile, the microwave signal that ablating electrode alternating receipts sends from ablation tissue, transfers to described microwave signal process system, converts microwave signal to temperature signal, thus the variations in temperature of reflection ablation tissue.
16. ablation methods as claimed in claim 15, is characterized in that, time-sharing circuit alternately controls the transmitting of described ablating electrode and melts radiofrequency signal, and receives described microwave signal.
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| CN201410427855.2A CN105361944A (en) | 2014-08-27 | 2014-08-27 | Ablation catheter and method using same to implement ablation |
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| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
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