CN105380626A - Continuous non-invasive blood pressure detection system - Google Patents
Continuous non-invasive blood pressure detection system Download PDFInfo
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- CN105380626A CN105380626A CN201510987037.2A CN201510987037A CN105380626A CN 105380626 A CN105380626 A CN 105380626A CN 201510987037 A CN201510987037 A CN 201510987037A CN 105380626 A CN105380626 A CN 105380626A
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- Prior art keywords
- blood pressure
- circuit
- processing circuit
- computer
- filtering
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/06—Accessories for medical measuring apparatus
Abstract
The invention discloses a continuous non-invasive blood pressure detection system which comprises a sensor circuit, a filtering and amplifying circuit, a data collecting and processing circuit and a computer. The continuous non-invasive blood pressure detection system is characterized in that the sensor circuit, the filtering and amplifying circuit, the data collecting and processing circuit and the computer are sequentially connected in order; the filtering and amplifying circuit adopts an AD620 amplifier of an Analog company as a first-stage amplifier; a serial port protocol adopted by the sensor circuit, the filtering and amplifying circuit, the data collecting and processing circuit and the computer is set by the RS232, the Baud rate is set as 9600, 88 data bits are set, one stop bit is set, and no parity check bit is selected; the data collecting and processing circuit adopts an MSP430 single chip microcomputer as a control chip. According to the continuous non-invasive blood pressure detection system, by adopting the low-power dissipation MSP430 single chip microcomputer as the control chip, the power dissipation of the system is lowered while the processing speed of the system is increased; the influences of various factors such as physical condition, environmental conditions and biorhythms on blood pressure measurement are reduced by adopting a continuous measuring method.
Description
Technical field
what the present invention relates to is a kind of embedded detection system, particularly a kind of continuous non-invasive blood pressure detecting system.
Background technology
blood pressure is exactly that blood vessel wall is subject to blood flow and impacts and the pressure that produces, can detect physiological situation as a very important mark.Along with the emotion changes of people, physiological conditions change and the change of the interior external world all can have an impact, and the index for aspects such as Index for diagnosis all has great significance.Blood pressure measuring method is divided into two kinds, the direct method of measurement and the indirect method of measurement.The method of direct measurement is the most also internationally recognized, but it has wound, and the requirement of technological layer is higher, compares the Real-Time Monitoring being suitable for patient with severe symptoms.Non-invasive measurement method is exactly the another kind of saying of indirect inspection, this fairly simple, so clinical monitoring is commonly used.Because blood pressure is along with the emotion changes of people, physiological conditions change and the change of the interior external world, so discontinuity measures the concrete condition that can not obtain human body well, continuous measurement just seems more important to clinical practice for the consecutive variations measurement of each pulse cycle.
the research of noinvasive continuous measurement has very important significance, include following some.The first, this measuring method has very important meaning for hypertensive treatment and diagnosis.Hypertension is the important risk factor of cardiovascular disease.Hypertensive real-time detection tool has very important significance, and is the important step of prevention cardiovascular acute disease for the timely use of medicine hyperpietic.Blood pressure lowering makes human body get back to normotensive value can the complication of effective prophylaxis of hypertension, and an important ring of this process is exactly the real-time grasp to pressure value, guarantees the blood pressure lowering of patient at period in a medicine continued smooth.Continuous measurement is carried out on blood pressure and can disclose the real-time change that medicine affects blood pressure, and more reasonably arrange drug administration by its affecting laws.
second, the continuous measurement of blood pressure can detect the cycle that pressure value changes, and know that this mechanical periodicity can be just hypertensive patient's service better, human body is when blood pressure can raise, and when blood pressure can reduce all can provide guidance foundation medicine time to hyperpietic.Change and the normal saliva of these blood pressures. the change of the sympathetic activity that the awake cycle parallels is relevant.For the blood pressure most meaning of every morning cardiovascular patient.By continuous print monitoring of blood pressure, can this symptom of Timeliness coverage, for the prediction of PD plays a very important role.The feature of fluctuation of blood pressure is that Amplitude Comparison is large, and the cycle is within 30S, can not obtain blood pressure information accurately by the single blood pressure measurement of routine.And continuous BP measurement can provide corresponding blood pressure transition information, to deduction and the sleep quality of sleep info, provide important evidence with the diagnosis of sleep disorder by stages.
3rd, arteriotony is as the responder of cardiovascular status, and cannot be measured the spacefarer of pressure value for a long time by cuff measuring method for Aero-Space etc., it is necessary for being monitored its blood pressure by pulse wave velocity method.Blood pressure detecting is for quiet and the normally eligible lower heart of function and blood circulation function criterion entire change rule, and a series of researchs that long duration space flight causes, and has important meaning.
Summary of the invention
the object of this invention is to provide a kind of blood pressure detecting system that can be used for continuous non-invasive blood pressure measurement, realize Measure blood pressure in each cardiac cycle process.
the object of the present invention is achieved like this:
a kind of continuous non-invasive blood pressure detecting system, comprises sensor circuit; Filter amplification circuit; Data acquisition processing circuit, computer; It is characterized in that: described sensor circuit; Filter amplification circuit; Data acquisition processing circuit, between computer, order connects successively; Described filter amplification circuit uses Analog company AD620 amplification to amplify as the first order; Described sensor circuit; Filter amplification circuit; Data acquisition processing circuit, the serial port protocol adopted between computer uses RS232 to arrange, and baud rate is set as 9600, and data bit is set as 88, and position of rest is set as 1, and no parity position is selected; Described data acquisition processing circuit adopts MSP430 single-chip microcomputer as control chip.
whole data acquisition and transmission system comprise following three parts: sensor circuit; Filter amplification circuit; Data acquisition process part.Choice for use Analog company AD620 amplifies and amplifies as the first order, and second level amplifying circuit needs signal gain to be brought up to general 400 times, and OP07 that applicable medical science aspect uses can be selected here as amplification.The access voltage output integrated of second level amplifying circuit after consideration and in conjunction with follow-up single-chip microcomputer is considered, circuit gain is promoted 51 times, overall gain reaches 388 times.After high-pass filtering, obviously can reduce the baseline drift of below 0.03HZ.The effect of low pass filter weakens high-frequency signal in a large number, and low frequency signal is passed through.Medical research shows, due to electrocardiosignal frequency mainly between, all the other signals all can be considered interfering signal.We select 100Hz as filtering node.
the collection pulse wave signal device that the present invention adopts is that blood oxygen refers to folder, realizes the measurement of blood oxygen saturation thus obtain pulse wave signal by reflection to red light.For reducing garbage signal to the interference of HONGGUANG, present invention employs light modulation techniques to reach the effect eliminating interference.Light modulation techniques just refers to by the signal madulation of a carry information on light wave, and makes the change of light intensity of wave or its series of parameters.Can well be rejected compared to the irregular background miscellaneous light of milli.System uses a photocell to receive transillumination, improves its degree of accuracy while this mode reduces power consumption.System realizes by MSP430F449 single-chip microcomputer 16 bit timing device module Timer_A that frequency is 50HZ, dutycycle is the sequence circuit of 50%.
the serial port protocol that system adopts uses RS232 to arrange.Baud rate is set as 9600, and data bit is set as 88, and position of rest is set as 1, and no parity position is selected.LabVIEW software is used to carry out the programming of software section.This part mainly completes the analysis and treament etc. of Design of Serial Communication, electrocardiosignal and pulse wave signal, realizes process and the display of electrocardiosignal and pulse wave signal thus.Here serial communication is realized by VISA, is called that the system of Virture Instrumentation Software Architecture is the concentric agreement of serial ports as communications with this of LabVIEW, by I/O port A
0
and A
1
.
advantage of the present invention is: the present invention adopts the MSP430 single-chip microcomputer of low-power consumption as control chip, reduces the power consumption of system while improve the processing speed of system.Method for continuous measuring is adopted to reduce the impact of the factors such as health, environmental condition, the physiology rhythm for blood pressure measurement.
Accompanying drawing explanation
fig. 1 is system principle structure chart of the present invention.
fig. 2 is main program flow chart of the present invention.
Detailed description of the invention
below in conjunction with accompanying drawing citing, the present invention is described in more detail:
embodiment 1
composition graphs 1, Fig. 1 is system principle structure chart of the present invention.Whole data acquisition and transmission system comprise following three parts: sensor circuit; Filter amplification circuit; Data acquisition process part.Choice for use Analog company AD620 amplifies and amplifies as the first order, and second level amplifying circuit needs signal gain to be brought up to general 400 times, and OP07 that applicable medical science aspect uses can be selected here as amplification.The access voltage output integrated of second level amplifying circuit after consideration and in conjunction with follow-up single-chip microcomputer is considered, circuit gain is promoted 51 times, overall gain reaches 388 times.After high-pass filtering, obviously can reduce the baseline drift of below 0.03HZ.The effect of low pass filter weakens high-frequency signal in a large number, and low frequency signal is passed through.Medical research shows, due to electrocardiosignal frequency mainly between, all the other signals all can be considered interfering signal.We select 100Hz as filtering node.
embodiment 2
composition graphs 2, the flow process of system is such:
(1) self-inspection is initialized;
(2) select sampling channel, (3) (4) are two passages;
(3) ecg signal acquiring, carries out the detection of R crest after extracting ecg wave form;
(4) pulse signal collection, submits pulse collection waveform to, and pulse characteristics point is monitored;
(5) pulse wave speed and characteristic point parameter is extracted;
(6) pressure value is calculated;
(7)
terminate.
Claims (1)
1. a continuous non-invasive blood pressure detecting system, comprises sensor circuit; Filter amplification circuit; Data acquisition processing circuit, computer; It is characterized in that: described sensor circuit; Filter amplification circuit; Data acquisition processing circuit, between computer, order connects successively; Described filter amplification circuit uses Analog company AD620 amplification to amplify as the first order; Described sensor circuit; Filter amplification circuit; Data acquisition processing circuit, the serial port protocol adopted between computer uses RS232 to arrange, and baud rate is set as 9600, and data bit is set as 88, and position of rest is set as 1, and no parity position is selected; Described data acquisition processing circuit adopts MSP430 single-chip microcomputer as control chip.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510987037.2A CN105380626A (en) | 2015-12-27 | 2015-12-27 | Continuous non-invasive blood pressure detection system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510987037.2A CN105380626A (en) | 2015-12-27 | 2015-12-27 | Continuous non-invasive blood pressure detection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105380626A true CN105380626A (en) | 2016-03-09 |
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|---|---|---|---|
| CN201510987037.2A Pending CN105380626A (en) | 2015-12-27 | 2015-12-27 | Continuous non-invasive blood pressure detection system |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040039254A1 (en) * | 2002-08-22 | 2004-02-26 | Stivoric John M. | Apparatus for detecting human physiological and contextual information |
| US20080190202A1 (en) * | 2006-03-03 | 2008-08-14 | Garmin Ltd. | Method and apparatus for determining the attachment position of a motion sensing apparatus |
| CN101791214A (en) * | 2010-01-19 | 2010-08-04 | 天津工程师范学院 | Community health-oriented portable monitoring system |
| CN104644145A (en) * | 2013-11-25 | 2015-05-27 | 哈尔滨智晟天诚科技开发有限公司 | Continuous non-invasive blood pressure measuring system |
-
2015
- 2015-12-27 CN CN201510987037.2A patent/CN105380626A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040039254A1 (en) * | 2002-08-22 | 2004-02-26 | Stivoric John M. | Apparatus for detecting human physiological and contextual information |
| US20080190202A1 (en) * | 2006-03-03 | 2008-08-14 | Garmin Ltd. | Method and apparatus for determining the attachment position of a motion sensing apparatus |
| CN101791214A (en) * | 2010-01-19 | 2010-08-04 | 天津工程师范学院 | Community health-oriented portable monitoring system |
| CN104644145A (en) * | 2013-11-25 | 2015-05-27 | 哈尔滨智晟天诚科技开发有限公司 | Continuous non-invasive blood pressure measuring system |
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Application publication date: 20160309 |